Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| ribonucleoside diphosphate reductase induced by bacteriophage t4. ii. allosteric regulation of substrate sepecificity and catalytic activity. | 1972 | 4565081 | |
| studies on the biochemical basis of spontaneous mutation. i. a comparison of the deoxyribonucleic acid polymerases of mutator, antimutator, and wild type strains of bacteriophage t4. | 1972 | 4565077 | |
| factors regulating triiodothyronine (t3) and thyroxine (t4) in blood. | 1972 | 4564709 | |
| degradation of escherichia coli chromosome after infection by bacteriophage t4: role of bacteriophage gene d2a. | mutations in the d2a gene of bacteriophage t4 have recently been shown to result in the stabilization of cytosine-containing phage deoxyribonucleic acid (dna) made after infection by phage gene 56 (deoxycytidine triphosphatase) mutants. in the experiments reported here, we investigate the role of the d2a gene in the degradation of the host chromosome. we find that if t4 endonuclease ii, a product of the phage gene dena, is active, host chromosome degradation appears normal, regardless of the pre ... | 1972 | 4564588 |
| association of replicative t4 deoxyribonucleic acid and bacterial membranes. | experiments utilizing cscl density gradient analysis and radioactive labels specific for bacteriophage t4 deoxyribonucleic acid (dna) and membranes have shown that replicative t4 dna is associated with host membranes. the association is inhibited by chloramphenicol and takes place just prior to semi-conservative replication of the phage dna. | 1972 | 4564586 |
| ribonucleotides covalently linked to deoxyribonucleic acid in t4 bacteriophage. | bacteriophage t4 was grown in the presence of labeled uridine. the deoxyribonucleic acid (dna) of the phage was shown to contain covalently attached ribonucleotides. the label appears not to be internal in the dna strands. presumably, it is at the ends of the dna strands and this may be related to dna initiation. | 1972 | 4564585 |
| on the direction of translation of the t4 deoxyribonucleic acid polymerase gene in vivo. | 1972 | 4564567 | |
| membrane protein synthesis after infection of escherichia coli b with phage t4: the riib protein. | 1972 | 4564529 | |
| an rna polymerase mutant of escherichia coli defective in the t4 viral transcription program. | 1972 | 4564523 | |
| a recombination gradient in bacteriophage t4 gene 34. | 1972 | 4564520 | |
| in vivo production of an rna-dna copolymer after infection of escherichia coli by bacteriophage t4. | an rna-dna copolymer was isolated from escherichia coli infected with bacteriophage t4. the rna and dna are covalently linked, and in the same polynucleotide strand. the dna of the copolymer hybridizes specifically to the left strand of phage t4 dna. the copolymer is produced in cells infected with amber mutants of phage t4 deficient in dna replication and is not inhibited by the addition of chloramphenicol. | 1972 | 4564205 |
| e. coli dna polymerase i and other host functions participate in t4 dna replication and recombination. | 1972 | 4564186 | |
| host cell deoxyribonucleic acid polymerase i and the support of t4 bacteriophage growth. | ultraviolet irradiation of escherichia coli pola(-) cells reduces their capacity to support the growth of t4 phage. there is no additional loss of capacity observed in pol tsa(-)reca(-) double mutants at the nonpermissive temperature. the reversion frequency of a t4 rii mutant after ultraviolet irradiation is not changed by the absence of host deoxyribonucleic acid polymerase i. | 1972 | 4563967 |
| exclusion of bacteriophages by t2 ghosts. | t2 ghosts do not exclude t4, t7, or lambda-induction in escherichia coli which survive ghost infection. latent periods are extended, probably by the temporary inhibition of protein synthesis. | 1972 | 4563601 |
| defective concatemer formation in cells infected with deoxyribonucleic acid-delay mutants of bacteriophage t4. | nonpermissive host cells infected with phage t4 mutants in genes 52, 39, and 58 through 61 are shown to form short intracellular single-stranded deoxyribonucleic acid in contrast to wild-type infected cells, which form dimers and trimers of t4 genome size. | 1972 | 4563599 |
| isolation and characterization of bacteriophage t4 base plates. | a method for isolating bacteriophage t4 base plates from lysates of escherichia coli b cells infected with the ts mutant in gene 19, ts b31 has been developed. by electrophoresis in polyacrylamide gel with sodium dodecyl sulfate the base plates have been shown to contain five to seven protein components with molecular weights of 36,000, 53,000, 66,000, 81,000, 87,000, and probably about 100,000. electron microscope studies have demonstrated that base plates may occur in two structural states: in ... | 1972 | 4563596 |
| effect of bacteriophage ghost infection on protein synthesis in escherichia coli. | the rate of protein synthesis by escherichia coli markedly decreased within 1 min after phage t4 infection, whereas a complete cessation of protein synthesis was observed within at least 25 sec after t4 ghost infection. the cellular level of amino acids and aminoacyl-transfer ribonucleic acid (trna) did not change drastically upon infection with ghosts, indicating that the inhibition of protein synthesis took place at a step(s) beyond aminoacyl-trna formation. the host messenger rna remained int ... | 1972 | 4563594 |
| a bacteriophage t4 mutant defective in protection against superinfecting phage. | 1972 | 4563589 | |
| role of genes 46 and 47 in bacteriophage t4 reproduction. ii. formation of gaps on parental dna of polynucleotide ligase defective mutants. | 1972 | 4563264 | |
| mouse thymus-independent and thymus-derived lymphoid cells. ii. ultrastructural studies. | the ultrastructural features of b-, t-, and surface ig(sig)-bearing cells have been studied on cell suspensions from lymphoid organs of mice at different stages of immunization. the cells were identified by exposure to rabbit antibodies against mouse-specific lymphocyte antigens (msla) or brain-associated theta antigen (batheta) for t cells, mouse-specific bone marrow-derived lymphocyte antigens (mbla) for b cells, and mouse ig for sig-bearing cells. the rabbit antibodies fixed on the cell surfa ... | 1972 | 4563148 |
| rna synthesis in t4 infected escherichia coli during amino acid starvation. | 1972 | 4563040 | |
| transcription in yeast: a factor that stimulates yeast rna polymerases. | yeast cells contain an rna polymerase factor, pi, which is a heat-stable protein with an apparent molecular weight of 12,000. this factor stimulates transcription of calf-thymus, salmon-sperm, yeast-nuclear, and t4-phage dna. it stimulates transcription by each of the four yeast-nuclear rna polymerases, by rat-liver rna polymerases i and ii, and by escherichia coli rna polymerase. pi-factor can cause each of the eukaryotic rna polymerases to become insensitive to rifamycin af-013, but does not s ... | 1972 | 4562741 |
| hybrid t4 r ii b cistrons created by genetic duplications. | 1972 | 4562710 | |
| transcription of bacteriophage t4 dna by escherichia coli rna polymerase in vitro: identification of some immediate-early and delayed-early genes. | 1972 | 4562318 | |
| role of the host cell in bacteriophage morphogenesis: effects of a bacterial mutation on t4 head assembly. | 1972 | 4561971 | |
| initial step of excision repair in escherichia coli: replacement of defective function of uvr mutants by t4 endonuclease v. | 1972 | 4561346 | |
| evidence that more deoxynucleotide kinase mrna is transcribed than translated during t4 infection of escherichia coli. | 1972 | 4561233 | |
| bacteriophage t4 head morphogenesis. iv. comparison of gene 16-, 17-, and 49-defective head structures. | defective heads present in extracts of bacteriophage t4 gene 16, 17, or 49 mutant-infected cells have been characterized. all appeared as empty shells when examined by negative-stain electron microscopy and showed essentially the same polypeptide pattern on sodium dodecyl sulfate-acrylamide gels. however, when analyzed by several other methods, gene 16- and 17-defective heads were shown to differ markedly from phage heads present in gene 49-defective extracts. first, the gene 16- and 17-defectiv ... | 1972 | 4561207 |
| bacteriophage t4 transfer rna. i. isolation and characterization of two-phage-coded nonsense suppressors. | 1972 | 4560761 | |
| self-association of gene-32 protein of bacteriophage t4. | the self-association of gene-32 protein has been studied by sedimentation equilibrium centrifugation and polyacrylamide gel electrophoresis, in order to better understand its role in dna replication and genetic recombination. the monomer molecular weight of gene-32 protein is 38,000 in guanidine hydrochloride and 34,000 in sodium dodecyl sulfate, in agreement with the results of alberts and coworkers. stable dimers of gene-32 protein occur under various conditions, among which are high ionic str ... | 1972 | 4560700 |
| in vitro complementation as an assay for new proteins required for bacteriophage t4 dna replication: purification of the complex specified by t4 genes 44 and 62. | we have developed an in vitro complementation assay for six t4 bacteriophage gene products believed to be components of the t4 dna replication apparatus. this assay is based upon the fact that dna synthesis in an infected cell lysate that lacks a given gene product is specifically stimulated by addition of the missing product. by the use of such an assay, two proteins that appear to be the products of t4 genes 44 and 62 have been purified to electrophoretic homogeneity as a single complex of the ... | 1972 | 4560698 |
| dna-directed synthesis in vitro of t4 phage-specific enzymes. | the synthesis of deoxynucleotide kinase (ec 2.7.4.2) in vitro by a preparation consisting of t4 bacteriophage dna and a cell-free extract of escherichia coli has been reported. a study of the role of monovalent cations in the synthesis of this enzyme as well as alpha-glucosyl transferase (ec 2.4.1.2) shows that potassium ions are required for maximal enzyme production. examination of the rna-directed system indicates that potassium ions are more effective than ammonium ion in the translation of ... | 1972 | 4560689 |
| an analysis of replication errors made by a defective t4 dna polymerase. | 1972 | 4560677 | |
| heterozygotes of three-factor crosses of bacteriophage t4. | 1972 | 4560676 | |
| ribosomes after t4-infection. | 1972 | 4560662 | |
| bacteriophage t4 transformation: an assay for mutations induced in vitro. | 1972 | 4559688 | |
| isolation and partial characterization of a mutant of escherichia coli deficient in dna polymerase ii. | a mutant of escherichia coli deficient in dna polymerase ii has been isolated from e. coli pola1 by mutagenesis with n-methyl-n'-nitro-n-nitrosoguanidine and assay of polymerase activity in extracts of survivors. the pola1 mutation was suppressed during mutagenesis by introduction of the suppressor, su7(+), into the parental strain. the mutant, hms83 pola1 polb1, contains less than 0.5% of the normal levels of dna polymerase ii. the only polymerase activity detected in the mutant is dna polymera ... | 1972 | 4559593 |
| effect of ionic strength, ph, amines and divalent cations on the lytic activity of t4 lysozyme. | 1972 | 4559097 | |
| use of immunologically modified bacteriophage t4 in detection of antibodies to nucleic acids. | 1972 | 4558243 | |
| specificity of protein synthesis by bacterial ribosomes and initiation factors: absence of change after phage t4 infection. | 1972 | 4557601 | |
| contribution of thymine dimers to the ultraviolet light inactivation of mutants of bacteriophage t4. | 1972 | 4557200 | |
| triplet-state sensitization of thymine photodimerization in bacteriophage t4. | 1972 | 4557199 | |
| mutagenic effects of thymine dimers in bacteriophage t4. | 1972 | 4557194 | |
| studies on t4 lysozyme. affinity for chitin and the use of chitin in the purification of the enzyme. | 1972 | 4556563 | |
| on the direction of reading of bacteriophage t4 gene 43 (deoxyribonucleic acid polymerase). | amber (am) mutants of the two closely linked sites, b22 and c125, in bacteriophage t4 gene 43 [deoxyribonucleic acid (dna) polymerase] synthesize in the nonpermissive (su(-)) escherichia coli host gene 43 products which are devoid of dna polymerase activity, but which retain a 3'-exonuclease activity. diethylaminoethyl-cellulose chromatographic analysis of dna polymerase and deoxyribonuclease activities from extracts of su(-) cells infected with single- and double-am mutants of t4 gene 43 showed ... | 1972 | 4556512 |
| effects of ionizing radiation on the capacity of escherichia coli to support bacteriophage t4 growth. | the loss in capacity of irradiated bacteria to support the growth of t4 phage has been studied for two strains, escherichia coli b and e. coli b(s-1). following a dose of 25 krads, the capacity is quite rapidly lost during postirradiation incubation so that after two hr of such incubation at 37 c only 12% remains in strain b and 3% in strain b(s-1). evidence that capacity is lost in an all-or-none fashion was provided by two types of experiments: (i) a single-burst analysis of those cells which ... | 1972 | 4556509 |
| a new gene of bacteriophage t4 determining immunity against superinfecting ghosts and phage in t4-infected escherichia coli. | 1972 | 4555610 | |
| the action of bacteriophage t4 ghosts on escherichia coli and the immunity to this action developed in cells preinfected with t4. | 1972 | 4555609 | |
| hydrolysis of template and newly synthesized deoxyribonucleic acid by the 3' to 5' exonuclease activity of the t4 deoxyribonucleic acid polymerase. | 1972 | 4555423 | |
| induction of a new enzyme activity to excise pyrimidine dimers in escherichia coli infected with bacteriophage t4. | 1972 | 4555248 | |
| control by bacteriophage t4 of the reduction of adenosine nucleotide to deoxyadenosine nucleotide. | 1972 | 4554915 | |
| on the exonuclease activity of phage t4 deoxyribonucleic acid polymerase. | 1972 | 4554914 | |
| infection of escherichia coli by t2 and t4 bacteriophages as seen in the electron microscope: t4 head morphogenesis. | bacteriophage t4 capsids seem to be assembled on e. coli protoplasmic membranes. this process seems to involve "lumps" of head protein, which convert to tau particles, which in turn give rise to empty heads. the empty heads leave the bacterial membrane and are then filled with dna in the central region of the cell. t4 gene 16 and 17 products appear to be necessary for head filling. | 1972 | 4554535 |
| identification of some antigenic precursors of bacteriophage t4. | 1972 | 4554113 | |
| molecular basis of a mutational hot spot in the lysozyme gene of bacteriophage t4. | 1972 | 4553645 | |
| effects of oxidized spermine and acrolein on the transforming activity of t4 dna. | 1972 | 4552901 | |
| bacteriophage lysozyme synthesis in escherichia coli k-12(lambda) infected with rii mutant of bacteriophage t4. | when escherichia coli k-12(lambda) was infected with a t4rii bacteriophage, synthesis of lysozyme appeared at the normal time but stopped 15 min after infection. the lysozyme produced was 1% of the normal level. | 1972 | 4552555 |
| inactivation of bacteriophage t4 by ethyl methanesulfonate: influence of host and viral genotypes. | inactivation of bacteriophage t4 by ethyl methanesulfonate (ems) is a complex process which depends critically upon the conditions of treatment and upon both the viral and the host genotypes. ems-inactivated particles are capable of multiplicity and cross-reactivation, indicating the need for caution in using ems in certain types of mutation studies. the pyrimidine dimer excision systems of the phage and the host do not affect the ems sensitivity of t4, but the t4x(+)y(+) system does. mutational ... | 1972 | 4552551 |
| polyamines in the synthesis of bacteriophage deoxyribonucleic acid. ii. requirement for polyamines in t4 infection of a polyamine auxotroph. | polyamine depletion produced by exogenous arginine in escherichia colik-12 cultures defective in agmatine ureohydrolase activity resulted in a marked inhibition of the rates of growth and nucleic acid synthesis. addition of putrescine or spermidine to such depleted cultures restored the control rate of growth and nucleic acid accumulation. the omission of lysine resulted in a further decrease in the rates of growth and nucleic acid synthesis in polyamine-depleted cells. the addition of exogenous ... | 1972 | 4552550 |
| polyamines in the synthesis of bacteriophage deoxyribonucleic acid. i. lack of dependence of polyamine synthesis on bacteriophage deoxyribonucleic acid synthesis. | to determine whether polyamine synthesis is dependent on deoxyribonucleic acid (dna) synthesis, polyamine levels were estimated after infection of bacterial cells with ultraviolet-irradiated t4 or t4 am n 122, a dna-negative mutant. although phage dna accumulation was restricted to various degrees in comparison to cells infected with t4d, nearly commensurate levels of putrescine and spermidine synthesis were observed after infection, regardless of the rate of phage dna synthesis. we conclude fro ... | 1972 | 4552549 |
| bacteriophage t4 head morphogenesis. ii. studies on the maturation of gene 49-defective head intermediates. | an investigation into the metabolic requirements for maturation of gene 49-defective heads indicated that adenosine triphosphate energy and continued deoxyribonucleic acid (dna) but not ribonucleic acid synthesis were needed. the fate of dna present at restrictive temperatures (41.5 c) in tsc9 (gene 49)-infected cells was also examined. after lysis of infected cells, the 12 to 32% deoxyribonuclease-resistant dna associated with isolated gene 49-defective heads was found to be attached to a deoxy ... | 1972 | 4552417 |
| translational regulation of deoxycytidylate hydroxymethylase and deoxynucleotide kinase synthesis in t4-infected escherichia coli. | 1972 | 4551997 | |
| control of pyrimidine biosynthesis by phage t4. ii. in vitro complementation between ribonucleotide reductase mutants. | 1972 | 4551996 | |
| new small polypeptides associated with dna-dependent rna polymerase of escherichia coli after infection with bacteriophage t4. | four new small polypeptides are associated with dna-dependent rna polymerase from e. coli after infection with t4 phage. the new polypeptides are easily detected in rna polymerase from e. coli cells labeled with amino acids after phage infection. their molecular weights range from 10,000 to 22,000, as detected by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. all four polypeptides are found after infection with either wild-type t4 phage or t4 early amber mutants in ... | 1972 | 4551978 |
| correlation between the reduction of phage lysozyme level and the time of lysis in escherichia coli infected by bacteriophage t4. | 1972 | 4551920 | |
| activation of a defective dna polymerase in a temperature-sensitive mutant of bacteriophage t4. | 1972 | 4550900 | |
| suppression of dna-arrested synthesis in mutants defective in gene 59 of bacteriophage t4. | 1972 | 4550789 | |
| differential synthesis of proteins by t4 phage and its head protein amber mutant. | 1972 | 4550696 | |
| t4 endonuclease iv. improved purification procedure and resolution from t4 endonuclease 3. | 1972 | 4550601 | |
| lethality and dna breakage from 32p and 33p decay in bacteriophage t4. | 1974 | 4547368 | |
| induction of lethality and dna breakage by the decay of iodine-125 in bacteriophage t4. | 1974 | 4543814 | |
| the let factor in mutagenesis by ionizing radiations. i. reversion to wild type of a bacteriophage t4 amber mutant. | 1973 | 4542986 | |
| plasmapheresis in the treatment of thyrotoxic crisis (measurement of half-concentration times for free and total t3 and t4). | 1973 | 4542105 | |
| a comparison between the "oxford t4 by column" method and the murphy-pattee method for serum thyroxine. | 1973 | 4542100 | |
| experimental thyrotoxicosis: effects of graded doses of t4 plus t3. | 1973 | 4542079 | |
| n-methyl-n'-nitro-n-nitrosoguanidine and hydroxylamine induced mutants of the rii region of phage t4. | 1974 | 4536415 | |
| the three dimensional structure of the lysozyme from bacteriophage t4. | the three dimensional structure of the lysozyme from bacteriophage t4 has been determined from a 2.5 a resolution electron density map. about 60% of the molecule is in a helical conformation and there is one region consisting of antiparallel beta-structure. the polypeptide backbone folds into two distinct lobes linked in part by a long helix. in the region between the two lobes, there is a cleft which deepens into a hole or cavity, about 6-8 a in diameter, extending from one side of the molecule ... | 1974 | 4530293 |
| chemical synthesis of a primer and its use in the sequence analysis of the lysozyme gene of bacteriophage t4. | we have developed a general approach for determining the nucleotide sequence of a gene, with the aid of a deoxyribonucleotide primer of defined sequence. the selection of the primer sequence was based on a short segment of mrna sequence of t4 phage lysozyme. a tetradecadeoxyribonucleotide primer was chemically synthesized and its sequence verified by sequence analysis. this primer was found to bind to the single-stranded region of the exonuclease iii-treated t4 dna, and specific nucleotides were ... | 1974 | 4526223 |
| direct participation of dcmp hydroxymethylase in synthesis of bacteriophage t4 dna. | in order to retain in an in situ system the control mechanisms involved in synthesis of bacteriophage t4 dna, infected cells were made permeable to nucleotides by plasmolysis with concentrated sucrose. such preparations use exogenous deoxyribonucleotides to synthesize t4 phage dna. as has been observed with in vivo studies, dna synthesis was drastically reduced in plasmolyzed preparations from cells infected by amber mutants of genes 1, 32, 41, 42, 43, 44, or 45. added 5-hydroxymethyl dctp did n ... | 1973 | 4525160 |
| adriamycin and daunorubicin inhibition of mutant t4 dna polymerases. | the anticancer drugs, adriamycin and daunorubicin, as well as two other dna reagents, ethidium bromide and 9-aminoacridine, all exert a differential inhibitory effect on nucleotide incorporation for purified dna polymerases induced by mutant and wild-type bacteriophage t4. when compared with dna polymerase of wild-type phage, antimutator enzymes are inhibited to a far greater extent and mutator enzymes to a lesser extent. in contrast, the polymerase-associated 3'-exonuclease activities of wild t ... | 1974 | 4524632 |
| structure of nascent phix174 replicative form: evidence for discontinuous dna replication. | varphix174 rf (replicative form) ii dna, labeled in vivo with [methyl-(3)h]thymidine, was isolated from escherichia coli pola (dna polymerase i-deficient) and pola(+) cells during rf replication. [(32)p]dcmp was incorporated into the gaps present in the rf ii dna with [alpha-(32)p]dctp and t4 dna polymerase. sedimentation in alkaline sucrose gradients revealed that much of the incorporated (32)p was present in a heterogeneous collection of fragments shorter than unit length. inclusion of polynuc ... | 1974 | 4522806 |
| breakdown of hela cell dna mediated by vaccinia virus. | breakdown of hela cell dna begins within 90 min after infection with vaccinia virus at a multiplicity of infection of 2-plaque-forming units per cell, and ends about 7.5 hr after infection. hela cell dna is degraded to a uniform size of 1 to 2 x 10(7) daltons, as judged by alkaline sucrose sedimentation analysis. the rate of host-cell dna degradation by vaccinia virus increased directly with the multiplicity of infection. sedimentation patterns in neutral and alkaline sucrose gradients of viral ... | 1973 | 4522298 |
| formation in vitro of infective joint molecules of lambda dna by t4 gene-32 protein. | half molecules of lambda dna that had been partially digested by lambda exonuclease to expose homologous single strands were rejoined by the action of t4 gene-32 protein at 37 degrees in the presence of mg(++). measurements of infectivity in su(-) spheroplasts and sedimentation in sucrose demonstrated the formation of sus(+) joint molecules from two preparations of sheared lambda dna that carried sus mutations at opposite ends of the genome. the biological activity of joint molecules made by ann ... | 1974 | 4521814 |
| transfer rna biosynthesis: the nucleotide sequence of a precursor to serine and proline transfer rnas. | the nucleotide sequence of a transfer rna precursor molecule coded by bacteriophage t4 has been determined. the molecule is a single polynucleotide chain which contains two transfer rna species that are destined to recognize serine and proline. the 3' -cca(oh) termini of both mature transfer rna species are absent in the precursor molecule; these termini must therefore be added enzymatically at a subsequent stage of maturation. nucleotide residues unique to the precursor are located at both ends ... | 1974 | 4521813 |
| identification of trna precursor molecules made by phage t4. | 1973 | 4519024 | |
| bacteriophage t4 head morphogenesis. isolation, partial characterization, and fate of gene 21-defective tau-particles. | a lysozyme-detergent procedure was developed for isolation of tau-particles from cells infected by gene-21 mutants of t4 bacteriophage. these particles have a sedimentation coefficient of 440 +/- 10 s. they contain less than 1% detectable nuclease-resistant dna, are smaller (650 x 850 a) than normal bacteriophage heads (800 x 1100 a), and exhibit two major bands on 7.5% na dodecyl sulfate-acrylamide gels. the more prominent band (55,000 daltons) corresponds to the uncleaved, major capsid polypep ... | 1973 | 4515924 |
| assembly core of bacteriophage t4: an intermediate in head formation. | 1973 | 4512235 | |
| bacteriophage t4 trna leu . | 1972 | 4508375 | |
| protection of t4 bacteriophage against inactivation during freezing and thawing by addition of peptides. | peptides of rabbit globin produced by tryptic digestion, were found to be highly protective against inactivation of freeze-thawed t4 phage. in concentrations of about 10(-3) m the peptides protected the phage against inactivation by both concentrated nabr in the unfrozen aqueous phase and the eutectic phase change.fractionation of the peptides by g25 sephadex showed that peptide concentration rather than peptide size was the more important factor in determining the degree of protection of the ph ... | 1972 | 4506995 |
| osmotic injury in rapidly thawed t4 bacteriophage. | osmotic injury in frozen-thawed t4 phage was caused by the sudden and large fall in the electrolyte concentration of the unfrozen aqueous phase during rapid thawing of frozen samples. in accordance with the classical interpretation of osmotic shock it was found that dna was quantitatively liberated from t4 phage inactivated by the osmotic injury of rapid thawing.the degree of inactivation of osmotically shocked t4 phage was temperature dependent, being much increased by lowering the temperature, ... | 1972 | 4506994 |
| t4 transfer rnas: codon recognition and translational properties. | t4 phage transfer rnas recognize the previously assigned codons for a given amino acid; however, they tend to prefer code words that are less well recognized by their host. the phage transfer rnas are more effective in polypeptide synthesis with t4 rather than escherichia coli messenger rnas. | 1972 | 4504324 |
| detection of polyadenylic acid sequences in viral and eukaryotic rna(polu(u)-cellulose columns-poly(u) filters-fiberglass-hela cells-bacteriophage t4). | a rapid and specific technique to detect polyriboadenylic acid sequences in rna is described. the method depends upon the ability of rnas that contain poly(a) sequences to associate specifically with poly(u) that has been immobilized on fiberglass filters by ultraviolet irradiation. a high proportion of the transcripts synthesized in vivo and in vitro from the vaccinia virus genome contain poly(a) sequences and bind to the poly(u) filters. similarly, dna-like rna from the nucleus and from the cy ... | 1972 | 4501121 |
| [proceedings: thyroid stimulating substances in man. (1). new findings concerning autoregulation of the thyroid gland of man: increases of adenyl cyclase caused by tsh administration and their inhibition by t3 and t4 in the thyroid of normal individuals and patients with basedow's disease]. | 1974 | 4480296 | |
| [proceedings: blood t3-t4 ratio in various states of thyroid function]. | 1974 | 4480291 | |
| [proceedings: relationship between changes of the serum t3 level, t4-t3 ratio and the hypothalamo-pituitary system in the newborn]. | 1974 | 4476613 | |
| [proceedings: fluctuation of serum tsh concentration caused by t3 and t4 treatment in patients with primary hypothyroidism]. | 1974 | 4476486 | |
| [proceedings: fluctuation of blood t3 and t4 levels in hyperthyroidism during therapy]. | 1974 | 4476483 | |
| [proceedings: peripheral metabolism of 125 i-t4 and 131 i-t3 and conversion of t4 to t3]. | 1974 | 4476284 | |
| [serum triiodothyronine in newborn infants and its relationship with t4 and tsh]. | 1974 | 4473288 | |
| [comparative study of mutagenesis in amber mutants of bacteriophage t4]. | 1974 | 4469514 |