Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| detection of foot and mouth disease virus by rt-pcr and microplate hydridization assay using inactivated viral antigens. | a single step rt-pcr was tested for detection of foot and mouth disease virus (fmdv) and immunoenzymatic determination of amplified products in a microplate hybridization assay. inactivated reference strains (elisa antigen) of all seven serotypes were used to optimize the test. oligonucleotide primers were selected from two different genomic regions coding for rna polymerase and vp1 protein, respectively. the rt-pcr used to amplify the polymerase gene specific rna detected fmdv strains a, c, o, ... | 2004 | 14992244 |
| molecular phylogeny of leader proteinase gene of type a of foot-and-mouth disease virus from india. | we previously demonstrated the presence of three genotypes (iv, vi and vii) of type a (subtype a22) of foot-and-mouth disease virus (fmdv) in india based on 1d gene sequence analysis. in the present study, the leader proteinase (l(pro)) gene sequences of 35 type a fmdv field isolates sampled over a period of 24 years (1977-2000) have been analyzed. maximum-likelihood (ml) phylogenetic analysis revealed four distinct genetic lineages (a-d), indicating high divergence in l gene of type a fmdv. lin ... | 2004 | 14991441 |
| stable, stoichiometric delivery of diverse protein functions. | as contemporary "genomics" steadily reveals an increasing number of novel gene sequences, the need for efficient methodologies to functionally characterize these genes in vivo increases significantly. reliable coupling of target gene expression to a variety of surrogate reporter functions is critical to properly assay novel gene function in complex cell populations. ideally, independent target and reporter proteins would be derived from a single open reading frame creating a stoichiometric relat ... | 2004 | 14980783 |
| quantitative estimates of the risk of new outbreaks of foot-and-mouth disease as a result of burning pyres. | the risk of dispersing foot-and-mouth disease virus into the atmosphere, and spreading it to susceptible holdings as a result of burning large numbers of carcases together on open pyres, has been estimated for six selected pyres burned during the 2001 outbreak in the uk. the probability of an animal or holding becoming infected was dependent on the estimated level of exposure to the virus predicted from the concentrations of virus calculated by the met office, bracknell. in general, the probabil ... | 2004 | 14979669 |
| a simulation model of intraherd transmission of foot and mouth disease with reference to disease spread before and after clinical diagnosis. | intraherd transmission of foot and mouth disease virus (fmdv) was examined using a simulation model for a hypothetical 1,000-cow dairy, assuming clinical diagnosis was made when at least 1% (10 cows) or 5% (50 cows) had clinical signs of fmd, i index case cow, and transition state distributions for the latent, subclinically infectious, and clinically infectious periods of fmd calculated from published data. estimates assumed for the number of animal-to-animal contacts (k) adequate for transmissi ... | 2004 | 14974841 |
| [receptivity of autochthonous moroccan beef to the foot-and-mouth disease virus]. | 1952 | 14956125 | |
| [experimental studies on infection with the foot and mouth disease virus]. | 1951 | 14934819 | |
| research on foot- and mouth disease; cultivation of the foot-and-mouth disease virus in explanted epithelium of the bovine tongue. iv. tissue and medium variations. | 1952 | 14924106 | |
| an investigation of the foot- and mouth disease virus by the use of electrophoresis in filter paper. | 1952 | 14924105 | |
| the determination of the sedimentation constant of a homogeneous component having the characteristics of the foot- and mouth disease virus. | 1952 | 14924104 | |
| propagation of strains of foot-and-mouth disease virus in unweaned white mice. | 1951 | 14911842 | |
| [receptivity of autochthonous moroccan cattle to foot and mouth disease virus]. | 1951 | 14896572 | |
| [massive culture of foot and mouth disease virus on fetal skin in deproteined and purified amniotic fluid]. | 1951 | 14870383 | |
| [dermotropic viruses. 7. foot and mouth disease virus]. | 1951 | 14865023 | |
| in vitro cultivation of the mexican strain (vallée a type) of foot-and-mouth disease virus. | 1951 | 14850745 | |
| combination of foot- and mouth disease virus albumen and protamine. | 1950 | 14846638 | |
| [behavior of foot and mouth disease virus in asbestos filters]. | 1951 | 14845629 | |
| [a compound of foot and mouth disease virus with serum albumin and protamine]. | 1951 | 14822561 | |
| extent of reduction of foot-and-mouth disease virus rna load in oesophageal-pharyngeal fluid after peak levels may be a critical determinant of virus persistence in infected cattle. | to investigate whether foot-and-mouth disease virus (fmdv) rna loads in oesophageal-pharyngeal fluid (op-fluid) in the early course of infection is related to the outcome of virus persistence, viral rna in op-fluid samples from cattle experimentally infected with fmdv type o was quantitatively analysed by using a quantitative real-time rt-pcr. viral rna was detected within 24 h post-infection (p.i.) in all infected animals. rapid virus replication led to peak levels of viral rna load by 30-53 h ... | 2004 | 14769899 |
| expression of a foot-and-mouth disease virus immunodominant epitope by a filamentous bacteriophage vector. | we described the construction of a recombinant filamentous phage displaying on its surface the immunodominant site of vp1 protein of foot-and-mouth disease virus (fmdv). the coding sequence was inserted at the amino-terminus of the major coat protein pviii via a spacer. the hybrid phage proved to be antigenic as it was recognized by polyclonal and monoclonal anti fmdv sera. in two experiments involving immunisation of guinea-pigs with the recombinant phage, a low antibody response was generated. ... | 2004 | 14745601 |
| evaluation of real-time reverse transcription polymerase chain reaction assays for the detection of swine vesicular disease virus. | differential detection of swine vesicular disease virus (svdv) from the other vesicular disease viruses of foot-and-mouth disease (fmd), vesicular stomatitis (vs) and vesivirus is important as the vesicular lesions produced by these viruses are indistinguishable in pigs. two independent sets of primers and probe, designed from nucleotide sequences within the 5' untranslated region (utr) of the svdv genome, were evaluated in a real-time (5' nuclease probe-based or fluorogenic) pcr format. althoug ... | 2004 | 14738984 |
| comparison of elisa for the detection of porcine serum antibodies to non-structural proteins of foot-and-mouth disease virus. | three foot-and-mouth disease virus non-structural protein antibody detection kits, chekit fmd-3abc, ubi fmd ns eia and dvivr nsp elisa, were compared in the study. the results showed that the specificity of the kits ranged from 96.7 to 100% in nai;ve pigs and from 93.6 to 98.1% in vaccinated pigs, and that the dvivr kit had the highest analytical sensitivity. the kappa statistics for the detection of 612 sera were 0.582, 0.447 and 0.658 for chekit/ubi, chekit/dvivr and ubi/dvivr, respectively. t ... | 2004 | 14738982 |
| no foot-and-mouth disease virus transmission between individually housed calves. | the foot-and-mouth disease outbreak in the netherlands in 2001 most likely started on a mixed veal-calf/dairy-goat farm. the outbreak among the 74 calves on this farm appeared to be limited to four animals, and no clinical signs of fmd were reported. also on a second veal-calf farm minor clinical signs and limited virus transmission were observed. since fmd is known to be a very contagious disease, and can cause severe lesions, these observations were disputed. therefore, we carried out two expe ... | 2004 | 14738779 |
| studies of genetically defined chimeras of a european type a virus and a south african territories type 2 virus reveal growth determinants for foot-and-mouth disease virus. | the three south african territories (sat) types of foot-and-mouth disease virus (fmdv) display great genetic and antigenic diversity, resulting from the independent evolution of these viruses in different geographical localities. for effective control of the disease in such areas, the use of custom-made vaccines is required. to circumvent the tedious process of vaccine strain selection, an alternative in the control process is being investigated. specifically, it is proposed to replace the antig ... | 2004 | 14718620 |
| serosurveillance of wild deer and wild boar after the epidemic of foot-and-mouth disease in the netherlands in 2001. | blood samples from 140 wild deer and 208 wild boar shot in the aftermath of the epidemic of foot-and-mouth disease in the netherlands in 2001 were examined for antibodies to foot-and-mouth disease virus. they were all negative. | 2003 | 14682541 |
| engineering better vaccines for foot-and-mouth disease. | although efficacious and safe, current vaccines for fmd suffer from drawbacks. among these are that the immune response to the vaccine interferes with the ability to detect vaccinated animals that have subsequently become infected and could carry and shed the virus, creating an obstacle to re-instating disease-free status to countries/regions that vaccinate to control outbreaks. multiple diagnostic tests are available to identify animals that have been infected with fmdv by detection of antibodi ... | 2003 | 14677679 |
| vaccines and foot-and-mouth disease eradication in south america. | foot-and-mouth disease (fmd) vaccines have been a component of disease control and eradication strategies in south america ever since the first national programmes were created in the 1960s. by the mid 1970s, with the aid of international loans, fmd control programmes were implemented in almost every country and control measures strengthened. livestock production forms are still a determining factor in the spread and prevalence of fmd and regional control/eradication strategies based on these fo ... | 2003 | 14677678 |
| vaccines and companion diagnostic tests for foot-and-mouth disease virus. an overview of the experience in south america. | vaccination constitutes an important control policy for foot-and-mouth disease (fmd) in affected areas with advanced eradication programmes, as well as in free regions that decide to use immunization as a control measure after a recent introduction of the disease. however, considering that vaccinated animals exposed to fmd virus can establish sub-clinical infection and eventually remain persistently infected, availability of tools to identify sub-clinical infection and its silent transmission wi ... | 2003 | 14677677 |
| emergence of a novel subgroup within the widely circulating lineage of foot-and-mouth disease virus serotype asia 1 in india. | the complete vp1 encoding (1d) gene of 54 foot-and-mouth disease (fmd) virus serotype asia1 field isolates, most of which were isolated during 2000 and 2001, was sequenced. the phylogenetic analysis identified a novel subgroup (>10% nucleotide divergence) within the widely circulating lineage of this serotype. the newly emerged viruses were responsible for disease outbreaks in both cattle and buffaloes and were present in six different states in the country. amino acid sequence comparison of the ... | 2004 | 14672859 |
| validation of a foot-and-mouth disease antibody screening solid-phase competition elisa (spce). | this paper describes the validation of a solid-phase competition enzyme-linked immunosorbent assay (spce) for the serological detection of antibody to serotype o foot-and-mouth disease (fmd) in sheep, cattle and pigs. the specificity of the spce was calculated from the results of testing known negative sera from sheep, cattle and pigs (n=3030, 1418 and 1495, respectively). the mean percentage inhibition (pi) for known negative sheep, cattle and pig sera were 19.3, 24.1 and 20.8%, respectively. t ... | 2004 | 14667530 |
| induction of an antigen-specific immune response and partial protection of cattle against challenge infection with foot-and-mouth disease virus (fmdv) after lipopeptide vaccination with fmdv-specific b-cell epitopes. | to evaluate the potential of chemically synthesized lipopeptides for vaccination against foot-and-mouth disease (fmd), seven lipopeptides containing the immunostimulating principle of bacterial lipoproteins and linear b-cell epitopes of fmdv strain o(1)kaufbeuren (o(1)k) were used to immunize cattle (n=7). animals were vaccinated once and 21 days after immunization animals were infected with the homologous virus. four animals were protected. after vaccination, as well as after challenge infectio ... | 2003 | 14645912 |
| role of nonstructural proteins 3a and 3b in host range and pathogenicity of foot-and-mouth disease virus. | the genome of foot-and-mouth disease virus (fmdv) differs from that of other picornaviruses in that it encodes a larger 3a protein (>50% longer than poliovirus 3a), as well as three copies of protein 3b (also known as vpg). previous studies have shown that a deletion of amino acids 93 to 102 of the 153-codon 3a protein is associated with an inability of a taiwanese strain of fmdv (o/taw/97) to cause disease in bovines. recently, an asian virus with a second 3a deletion (amino acids 133 to 143) h ... | 2003 | 14645558 |
| developments in diagnostic techniques for differentiating infection from vaccination in foot-and-mouth disease. | foot-and-mouth disease (fmd) is a highly contagious and economically significant disease of cattle, pigs, sheep, goats and wild ruminant species. the fmd virus genome encodes a unique polyprotein from which the different viral polypeptides are cleaved by viral proteases, including eight different non-structural proteins (nsps). both structural and non-structural antigens induce the production of antibodies in infected animals. in contrast, vaccinated animals which have not been exposed to replic ... | 2004 | 14623146 |
| molecular epidemiology of sat3-type foot-and-mouth disease. | vp1 gene nucleotide sequences of 51 sat3-type foot-and-mouth disease (fmd) viruses from seven southern and eastern african countries were used to infer a gene phylogeny. results obtained by phylogenetic analysis of the homologous 405 nt region corresponding to the c-terminal 128 amino acids of 1d and adjacent 7 amino acids of 2a indicate that there are six distinct virus lineages evolving independently in different geographical localities in accordance with the fmd topotype concept. topotypes i- ... | 2003 | 14618089 |
| immediate protection of swine from foot-and-mouth disease: a combination of adenoviruses expressing interferon alpha and a foot-and-mouth disease virus subunit vaccine. | we have previously shown that swine inoculated with recombinant, replication-defective human adenovirus type 5 containing the porcine interferon alpha gene (ad5-pifnalpha) are completely protected when challenged 1 day later with virulent foot-and-mouth disease virus (fmdv). in the current study, we examined the duration of protection afforded swine by ad5-pifnalpha and the ability of a combination of ad5-pifnalpha and a fmdv subunit vaccine delivered by ad5-a24 (an ad5 vector containing the cap ... | 2003 | 14615155 |
| conserved nucleotides within the j domain of the encephalomyocarditis virus internal ribosome entry site are required for activity and for interaction with eif4g. | the internal ribosome entry site (ires) elements of cardioviruses (e.g., encephalomyocarditis virus [emcv] and foot-and-mouth disease virus) are predicted to have very similar secondary structures. among these complex rna structures there is only rather limited complete sequence conservation. within the j domain of the emcv ires there are four highly conserved nucleotides (a704, c705, g723, and a724)., which are predicted to be unpaired and have been targeted for mutagenesis. using an ires-depen ... | 2003 | 14610168 |
| identification of foot-and-mouth disease from a captive kangaroo in a zoological garden in india. | 2003 | 14601799 | |
| construction of an infectious chimeric classical swine fever virus containing the 5'utr of bovine viral diarrhea virus, and its application as a universal internal positive control in real-time rt-pcr. | rt-pcr is used widely as a diagnostic method to detect and differentiate pestiviruses. the construction of two chimeric classical swine fever virus (csfv) recombinants based on a marker virus constructed previously [j. virol. 72 (1998) 5318-5322] is described. these viruses, termed va187cat_5utrbvd and va187cat_iresbvd, contain the entire 5' untranslated region (5'utr) or the internal ribosome entry site (ires) of bovine viral diarrhea virus (bvdv), respectively. both chimeric viruses proved to ... | 2003 | 14599682 |
| immune response in mice inoculated with plasmid dnas containing multiple-epitopes of foot-and-mouth disease virus. | this paper focuses on the development of candidate dna vaccine encoding antigenic epitopes of type o foot-and-mouth disease virus (fmdv). a series of plasmids encoding different combinations of b cell epitopes and a t cell epitope were constructed and characterized by inoculating balb/c mice. the specific antibodies were only detectable in the mice inoculated with plasmids encoding the t cell epitope and b cell epitopes from sites 5 and 1, within which site 5 includes residues 135-167 of vp1 and ... | 2003 | 14585679 |
| immunization with peptide-functionalized carbon nanotubes enhances virus-specific neutralizing antibody responses. | 2003 | 14583262 | |
| subpol: a novel sucrose-based polymer support for solid-phase peptide synthesis and affinity chromatography applications. | a novel sucrose-based polymer support (subpol) with tailored morphology suitable for the use in solid-phase peptide synthesis (spps) is described, and its application as a hydrophilic affinity matrix for the specific removal of fibrinogen from human plasma is demonstrated. after suspension polymerization of partly methacrylated 2,1':4,6-di-o-isopropylidene sucrose and subsequent removal of the protecting groups, hydrophilic spherical polymer beads were obtained. the morphology of the resulting r ... | 2003 | 14583037 |
| molecular diagnostics in an insecure world. | as of october 2001, the potential for use of infectious agents, such as anthrax, as weapons has been firmly established. it has been suggested that attacks on a nations' agriculture might be a preferred form of terrorism or economic disruption that would not have the attendant stigma of infecting and causing disease in humans. highly pathogenic avian influenza virus is on every top ten list available for potential agricultural bioweapon agents, generally following foot and mouth disease virus an ... | 2003 | 14575112 |
| structural organization of a viral ires depends on the integrity of the gnra motif. | little is known about the tertiary structure of internal ribosome entry site (ires) elements. the central domain of foot-and-mouth disease (fmdv) ires, named 3 or i, contains a conserved gnra motif, essential for ires activity. we have combined functional analysis with rna probing to define its structural organization. we have found that a uncg motif does not functionally substitute the gnra motif; moreover, binding of synthetic gnra stem-loops to domain 3 was significantly reduced in rnas beari ... | 2003 | 14561883 |
| synchronous loss of quasispecies memory in parallel viral lineages: a deterministic feature of viral quasispecies. | viral quasispecies are endowed with a memory of their past evolutionary history in the form of minority genomes of their mutant spectra. to determine the fate of memory genomes in evolving viral quasispecies, we have measured memory levels of antigenic variant of foot-and-mouth disease virus (fmdv) red, which includes an arg-glu-asp (red) at a surface antigenic loop of the viral capsid. the red reverted to the standard arg-gly-asp (rgd), and the red remained as memory in the evolving quasispecie ... | 2003 | 14556744 |
| studies of quantitative parameters of virus excretion and transmission in pigs and cattle experimentally infected with foot-and-mouth disease virus. | foot-and-mouth disease virus (fmdv) can be spread by a variety of mechanisms and the rate of spread, the incubation period and the severity of disease depend on a multitude of parameters, including the strain of virus, the dose received, the route of introduction, the animal species and the husbandry conditions. more knowledge with regard to these parameters is urgently needed to improve resource-efficient disease control. this report describes detailed studies of fmdv load, excretion and transm ... | 2003 | 14554125 |
| development of a novel quantitative real-time rt-pcr assay for the simultaneous detection of all serotypes of foot-and-mouth disease virus. | foot-and-mouth disease virus (fmdv) spreads extremely fast and the need for rapid and robust diagnostic virus detection systems was obvious during the recent european epidemic. using a novel real-time rt-pcr system based on primer-probe energy transfer (priproet) we present here an assay targeting the 3d gene of fmdv. the assay was validated for the efficacy to detect all known fmdv serotypes. the test method was linear over a range of at least 7 orders of magnitude and the detection limit was b ... | 2003 | 14551821 |
| chloride concentration discriminates between foot-and-mouth disease virus ires-dependent translation and classical scanning translation: new aspects of the picornavirus shutoff mechanism. | some picornaviruses might use the general increase of ionic strength in the host cell that occurs successively after infection to induce shutoff of host protein synthesis and to stimulate viral protein synthesis. in order to investigate this discrimination mode on a molecular level, in vitro experiments under different salt conditions comparing the foot-and-mouth disease virus (fmdv) internal ribosome entry site (ires)-dependent translation with the translation via the classical scanning mechani ... | 2003 | 14524471 |
| a stochastic-modeling evaluation of the foot-and-mouth-disease survey conducted after the outbreak in miyazaki, japan in 2000. | when foot-and-mouth-disease (fmd) was identified in miyazaki prefecture in march 2000, japan conducted an intensive serological and clinical survey in the areas surrounding the index herd. as a result of the survey during the 21 days of the movement-restriction period, two infected herds were detected and destroyed; there were no other cases in the months that followed. to evaluate the survey used for screening the disease-control area and surveillance area, we estimated the herd-level sensitivi ... | 2003 | 14516716 |
| high-pressure freezing in the study of animal pathogens. | high-pressure freezing is applicable to both morphological and immunocytochemical studies. we are investigating the morphogenesis of foot-and-mouth disease virus and african swine fever virus by the use of high-pressure freezing of infected cells. foot-and-mouth disease virus particles are not detected in sections of conventionally immersion-fixed infected cells, but when the cells are prepared by high-pressure freezing, newly formed virions are readily seen throughout the cell. we report two me ... | 2003 | 14516363 |
| recovery of infectious foot-and-mouth disease virus from suckling mice after direct inoculation with in vitro-transcribed rna. | we assayed the infectivity of naked foot-and-mouth disease virus (fmdv) rna by direct inoculation of suckling mice. our results demonstrate that transcripts generated from full-length cdna clones were infectious, as was virion-extracted rna. interestingly, infectious virus could be recovered from a mutant transcript encoding amino acid substitution l-147-->p in capsid protein vp1, known to be noninfectious for bhk-21 cells. the model described here provides a useful tool for virulence studies in ... | 2003 | 14512578 |
| adenovirus-mediated type i interferon expression delays and reduces disease signs in cattle challenged with foot-and-mouth disease virus. | foot-and-mouth disease (fmd) is an economically important disease of livestock. eliminating fmd outbreaks in previously disease-free countries often relies on restriction of animal movement and massive slaughter of infected and in-contact susceptible animals. to develop a more effective and humane fmd control strategy, we explored the possibility of using type i interferon (ifn-alpha/beta) as a novel anti-fmd agent. we have demonstrated previously that swine inoculated with replication-defective ... | 2003 | 14511462 |
| expression of foot-and-mouth disease virus epitopes in tobacco by a tobacco mosaic virus-based vector. | we expressed two immunogenic dominant epitopes of foot-and-mouth disease virus (fmdv) serotype o in tobacco plant using a vector based on a recombinant tobacco mosaic virus (tmv). the recombinant viruses tmvf11 and tmvf14 contained peptides of 11 and 14 amino acid residues, respectively, from fmdv vp 1 fused to the open reading frame of tmv coat protein (cp) gene between amino acid residues 154 and 155. tmvf11 and tmvf14 systemically infected tobacco plant and produced large quantities of stable ... | 2003 | 14505922 |
| immunogenicity of plasmids encoding t and b cell epitopes of foot-and-mouth disease virus (fmdv) in swine. | in this work, we have investigated the immune response in pigs to two recombinant plasmids containing immunodominant neutralizing antibody epitopes of foot-and-mouth disease virus structural protein (vp1) coexpressed with viral non-structural proteins as a source of t cell epitopes. the plasmid pcdna3.1/3d15 contained a sequence coding for the 3d polymerase upstream of a sequence coding for peptide fmdv15, a peptide derived from vp1, previously shown to stimulate protective immunity to foot-and- ... | 2003 | 14505908 |
| mutation in the 1d gene (vp1) of foot-and-mouth disease virus serotype asia1 during serial cytolytic infections in cell culture. | changes in the nucleotide sequence of the 1d gene of two vaccine strains (ind 63/72 and ind 491/97) of foot-and-mouth disease virus (fmdv) serotype asia1 during serial cytolytic infections in cell culture have been analyzed. sequence comparisons revealed a majority of transition mutations in ind 491/97. the mutation frequency of the 1d gene of ind 491/97 was about 4.5 to 6.0 fold higher than that of ind 63/72. at the amino acids 40-60 and 140-160 regions the mutation frequency was higher compare ... | 2003 | 14505092 |
| validation of a lightcycler-based reverse transcription polymerase chain reaction for the detection of foot-and-mouth disease virus. | a specific reverse transcription polymerase chain reaction (rt-pcr) for the detection of the polymerase gene (3d) of foot-and-mouth disease virus (fmdv) was developed and validated with an analytical sensitivity of equal to, to 1,000 times higher than that of a single passage virus isolation. the performance of the rt-pcr was determined in 180 runs. after implementation, 5.3% of the tests had to be rejected due to invalid controls (e.g. cross-contamination of negative controls). the diagnostic s ... | 2003 | 14500125 |
| substrate utilization in bovine kidney culture cells infected with foot-and-mouth disease virus. | 1962 | 14487506 | |
| acid production in normal and foot-and-mouth disease virus infected bovine kidney culture cells. | 1962 | 14487505 | |
| defined medium for growth of foot-and-mouth disease virus. | pledger, richard a. (plum island animal disease laboratory, greenport, n. y.) and jerome polatnick. defined medium for growth of foot-and-mouth disease virus. j. bacteriol. 83:579-583. 1962.-foot-and-mouth disease virus, grown in primary bovine calf-kidney cell layers with a defined medium containing glucose as the only organic substrate, produced virus titers equivalent to those obtained with complex media containing serum and lactalbumin hydrolyzate. mannose was the only other substrate examin ... | 1962 | 14487167 |
| effect of inhibitors on the metabolism of cells in tissue culture and on foot-and-mouth disease virus synthesis. | 1961 | 14487088 | |
| growth of foot-and-mouth disease virus in a fibroblastic cell line derived from hamster kidneys. | 1962 | 14476739 | |
| studies on the small particle complement-fixing antigen of foot-and-mouth disease virus. | 1960 | 14433745 | |
| effect of neutral red on plaque formation by foot-and-mouth disease virus. | 1960 | 14433464 | |
| growth of foot-and-mouth disease virus in bovine kidney cell suspensions. | 1960 | 14430952 | |
| absence, in cattle, of a phase of hypersensitivity to foot and mouth disease virus, during the development of immunity to foot and mouth disease after vaccination | 1960 | 14418656 | |
| [female mice in experimentation with foot and mouth disease virus]. | 1954 | 14379552 | |
| propagation of type c foot-and-mouth-disease virus in eggs and effects of the egg-cultivated virus on cattle. | 1955 | 14365177 | |
| further studies with foot-and-mouth-disease viruses in dayold chicks. | 1955 | 14365176 | |
| [various properties and new possibilities of tissue culture in vivo of aphthous fever virus]. | 1954 | 14352462 | |
| [separation of two antigenic constituents of aphthous virus by starch electrophoresis]. | 1954 | 14352446 | |
| long-term observations on the antibody responses of cattle vaccinated with modified strains of foot-and-mouth disease virus. i. primary responses. | 1965 | 14330933 | |
| [trial of type a european anti-aphthous vaccines against the new "middle-east" a strain developed in the laboratoire d'etlik-ankara in turkey (march 1965)]. | 1965 | 14330357 | |
| a field trial in south africa of an attenuated vaccine against foot-and-mouth disease. | 1965 | 14329718 | |
| foot-and-mouth disease virus: structural changes during reaction with cations and formaldehyde as deduced from absorbance measurements. | 1965 | 14329128 | |
| typing of the foot-and-mouth disease virus. cumulative quarterly report. | 1965 | 14325351 | |
| [investigation on the immunological relation between the aphthous fever virus and coxsackie virus]. | 1965 | 14325348 | |
| [sensitivity of a cell line of the swine kidney to sat type 1 aphthous virus of asia. strains from iran and turkey]. | 1965 | 14325347 | |
| freeze-drying of foot-and-mouth disease virus and storage stability of the infectivity of dried virus at 4 c. | foot-and-mouth disease virus, type a, strain 119, propagated in cultures of calf kidney cells and in the tongue epithelium of cattle was used. the process of freeze-drying was conducted in two cycles on unit volumes of 4 ml in pyrex ampoules, averaging 150 ampoules per run, and was studied separately from the problems of storage. ampoules containing freeze-dried virus were flame-sealed for either immediate study or storage at 4 c for later reference. tissue-culture virus dried with various addit ... | 1965 | 14325296 |
| a 65 s particle containing viral protein in cells infected with foot-and-mouth disease virus. | 1965 | 14324003 | |
| a line of polyoma-transformed bhk21 cells insusceptible to foot-and-mouth disease virus. | 1965 | 14324002 | |
| antibodies produced by guinea pigs infected with foot-and-mouth disease virus. | 1965 | 14321429 | |
| secretion of foot-and-mouth disease virus and antibody in the saliva of infected and immunized cattle. | 1965 | 14317611 | |
| a simplified method for preparing bovine kidney cells for growth on glass. | 1965 | 14316802 | |
| antibody response to the noninfectious 7 mu component of the virus of foot-and-mouth disease. | 1965 | 14297221 | |
| the influence of previously x-irradiated aqueous solutions on the infectivity of the viruses of foot-and-mouth disease and vesicular stomatitis. | 1965 | 14283042 | |
| evidence of genetic recombination in foot-and-mouth disease virus. | 1965 | 14277084 | |
| [study on the agglutination test of collodion particles sensitized with aphthous fever virus and prozone phenomenon]. | 1965 | 14276960 | |
| behavior of an attenuated strain of foot-and-mouth disease virus in culture. | 1965 | 14276293 | |
| inhibition of virus growth by a toxic factor from asbestos pad and cellulose acetate membrane filters. | 1965 | 14270733 | |
| treat lesions in heifers experimentally infected with foot-and mouth disease virus. | 1964 | 14266847 | |
| [preservation of frozen foot-and mouth disease virus]. | 1964 | 14257909 | |
| relationship of donor age to in vitro production of foot-and-mouth disease virus by mouse kidney cells. | multiplication of foot-and-mouth disease virus (fmdv) was compared in kidney cells from 7- to 35-day-old mice representing various degrees of age resistance to this virus. three types of cell preparations were used: primary monolayer cultures, suspensions of dispersed cells, and suspensions of minced tissue. virus multiplication in the two types of cell suspensions was related to the age of the donors both in regard to time when multiplication first became evident and to the amount of virus prod ... | 1965 | 14253488 |
| inhibition of multiplication of foot-and-mouth disease virus by guanidine hydrochloride. | 1964 | 14248709 | |
| virus specific ribonucleic acids in baby hamster kidney cells infected with foot-and-mouth disease virus. | 1964 | 14241236 | |
| a complement fixation technique for the quantitative measurement of antigenic differences between strains of the virus of foot-and-mouth disease. | 1964 | 14239920 | |
| observations on the duration of immunity in cattle after experimental infection with foot-and-mouth disease virus. | 1964 | 14234053 | |
| factors associated with anaphylactic reactions to chicken embryo foot-and-mouth disease vaccine and flury rabies vaccine in cattle of venezuela. | 1964 | 14227161 | |
| suppression of the inhibitory action of guanidine on virus multiplication by some amino acids. | 1964 | 14227028 | |
| further studies of the early antibody in the sea of cattle and guinea pigs infected with foot-and-mouth disease virus. | 1964 | 14218596 | |
| virulence and interferon production of strains of foot-and mouth disease virus. | 1964 | 14214392 | |
| relation of physiologic conditions to variations in susceptibility of mother mice to foot-and-mouth disease virus. | 1964 | 14210791 |