Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| effect of natural or vaccine-induced porcine circovirus type 2 (pcv2) immunity on fetal infection after artificial insemination with pcv2 spiked semen. | the objectives of this study were to determine if vaccination against porcine circovirus type 2 (pcv2) or previous pcv2 infection of the dam are sufficient to prevent fetal infection when dams are artificially inseminated with pcv2-spiked semen. nine sows (sus domestica) were allocated into three groups of three dams each: the pcv2 naïve negative control group 1 was artificially inseminated with extended pcv2 dna negative semen during estrus, whereas the extended semen used in the vaccinated gro ... | 2009 | 19559470 |
| natural orifice transluminal endoscopic surgery gastrotomy closure with an over-the-endoscope clip: a randomized, controlled porcine study (with videos). | secure endoscopic closure of transgastric natural orifice transluminal endoscopic surgery (notes) access is of paramount importance. the over-the-scope clip (otsc) system has previously been shown to be effective for notes gastrotomy closure. | 2009 | 19559416 |
| cell-cell adhesion in the prelaminar region of the optic nerve head: a possible target for ionic stress. | this paper aims to study the anterior surface of the optic nerve in relation to its ability to support a source of stress acting from the vitreous cavity. the intercellular junctions of the lining astrocytes mediated by cellular adhesion molecules (cams) may be the main targets for ionic stress. | 2009 | 19546602 |
| investigation of blood typing method for seoul national university miniature pig. | pig blood group antigens may be present on grafted tissue as 16 isoforms, including the major one, a substrance. seoul national university (snu) miniature pigs and domestic pigs were used in this study. polymerase chain reaction (pcr) was performed for the erythrocyte antigen a (eaa) gene, and reverse transcriptase-pcr for pig a transferase fucosyl transferase (fut) 1 and fut-2. the hemagglutination test was performed with murine monoclonal anti-a and anti-b antibodies (mab), and immunohistochem ... | 2009 | 19545757 |
| characterization of the replication-competent porcine endogenous retrovirus class b molecular clone originated from korean domestic pig. | xenotransplantation from pigs offers an opportunity to resolve the shortage of human organs. the porcine endogenous retrovirus (perv) cannot be eliminated because of its presence in the germline dna. three subgroups of the replication-competent perv (perv-a, perv-b, and perv-c) have been identified in pigs. we constructed a molecular clone of perv-b from a korean domestic pig bac clone containing perv genomes, and its replication competency was characterized in human cells. the pol region of per ... | 2009 | 19543822 |
| animal farm: pig in the middle. | 2009 | 19536212 | |
| endoscopic closure of large colonic perforations using an over-the-scope clip: a randomized controlled porcine study. | perforation of the colon is considered to be one of the most serious complications of flexible endoscopy. the over-the-scope clip system (otsc) has previously been shown to close small colonic perforations effectively. the aim of this randomized controlled porcine study was to compare acute closure strengths between the novel 11-mm over-the-scope-clip and surgical closure for large colonic perforations. | 2009 | 19533550 |
| from wild animals to domestic pets, an evolutionary view of domestication. | artificial selection is the selection of advantageous natural variation for human ends and is the mechanism by which most domestic species evolved. most domesticates have their origin in one of a few historic centers of domestication as farm animals. two notable exceptions are cats and dogs. wolf domestication was initiated late in the mesolithic when humans were nomadic hunter-gatherers. those wolves less afraid of humans scavenged nomadic hunting camps and over time developed utility, initiall ... | 2009 | 19528637 |
| a mathematical analysis of obstructed diffusion within skeletal muscle. | molecules are transported through the myofilament lattice of skeletal muscle fibers during muscle activation. the myofilaments, along with the myosin heads, sarcoplasmic reticulum, t-tubules, and mitochondria, obstruct the diffusion of molecules through the muscle fiber. in this work, we studied the process of obstructed diffusion within the myofilament lattice using monte carlo simulation, level-set and homogenization theory. we found that these intracellular obstacles significantly reduce the ... | 0 | 19527637 |
| association of intramyocardial high energy phosphate concentrations with quantitative measures of the ventricular fibrillation electrocardiogram waveform. | quantitative measures of the ventricular fibrillation (vf) electrocardiogram (ecg) have been correlated with the success of rescue shocks, making them ideal measures for guiding resuscitative interventions. correlation of intramyocardial energy stores with the change in quantitative vf ecg measures would provide mechanistic insight into their utility. we sought to investigate the relationship between intramyocardial energy stores and four quantitative ecg measures. | 2009 | 19523740 |
| toxoplasma gondii infection in wild boars (sus scrofa) bred in brazil. | domestic pigs are considered to be important sources of toxoplasma gondii infection for humans. due to the increased consumption of wild boar meat in brazil, this species may also be an important source of the parasite. the objective of the present study was to detect t. gondii infection in 306 blood samples collected from wild boars bred in the state of são paulo, brazil. samples were analyzed using the modified agglutination test (mat), and 14 (4.5%) of them yielded positive results. modern br ... | 2009 | 19515494 |
| selective versus nonselective arterial clamping during laparoscopic partial nephrectomy: impact upon renal function in the setting of a solitary kidney in a porcine model. | laparoscopic partial nephrectomy has emerged as a standard of care for small renal masses. nevertheless, there remains concern over the potential for irreversible insult to the kidney as a result of exposure to warm ischemia. we aim to investigate the utility of selective segmental arterial clamping as a means to reduce the potential for ischemic damage to a solitary kidney during laparoscopic partial nephrectomy utilizing a porcine model. | 2009 | 19514812 |
| lipid emulsion combined with epinephrine and vasopressin does not improve survival in a swine model of bupivacaine-induced cardiac arrest. | this study sought to evaluate the efficacy of lipid emulsion in reversing bupivacaine-induced cardiovascular collapse when added to a resuscitation protocol that included the use of epinephrine and vasopressin. | 2009 | 19512878 |
| first report of bvdv circulation in sheep in argentina. | pestiviruses are capable of infecting a wide range of animals within the order artyodactila. currently, the genus pestivirus includes bovine viral diarrhea virus 1 (bvdv-1) and 2 (bvdv-2), border disease virus (bdv), and classical swine fever virus (csfv). bvdv-1, bvdv-2 and bdv are able to cross species barrier to infect a wide range of hosts, whereas csfv is restricted to domestic pigs and wild boars. in argentina, 70% of cattle are seropositive to bvdv. although there were some serological st ... | 2009 | 19501923 |
| classification of worldwide bovine tuberculosis risk factors in cattle: a stratified approach. | the worldwide status of bovine tuberculosis (btb) as a zoonosis remains of great concern. this article reviews the main risk factors for btb in cattle based on a three-level classification: animal, herd and region/country level. a distinction is also made, whenever possible, between situations in developed and developing countries as the difference of context might have consequences in terms of risk of btb. recommendations are suggested to animal health professionals and scientists directly invo ... | 2009 | 19497258 |
| a comparison of kidney oxygenation profiles between partial and complete renal artery clamping during nephron sparing surgery in a porcine model. | to compare kidney oxygenation profiles between partial and complete renal artery clamping during nephron sparing surgery (nss) in a porcine model. | 2009 | 19497169 |
| enhanced external counterpulsation promotes growth cytokines-mediated myocardial angiogenesis in a porcine model of hypercholesterolemia. | enhanced external counterpulsation (eecp) improves ischemia in patients with refractory angina pectoris, but the mechanism remains unclear. to explore the mechanisms of eecp action, we detected progenitor cells presenting any of the following markers cd34(+), cd29(+), and cd106(+). | 2009 | 19493469 |
| closed-chest experimental porcine model of acute myocardial infarction-reperfusion. | progress in cardiovascular regenerative medicine research requires the availability of appropriate experimental animal models that are as close to humans as feasible. our objective was to assess the validity of a porcine endovascular model of myocardial infarction and reperfusion. | 2009 | 19490947 |
| drug delivery at the aortic valve tissues of healthy domestic pigs with a paclitaxel-eluting valvuloplasty balloon. | restenosis occurs invariably within 1 year following balloon valvulopasty in aortic valve stenosis. the mechanism of restenosis seems to involve a dynamic cellular component that could be a target for drug inhibition. we investigated the feasibility of local drug delivery at the aortic valve tissues of healthy pigs with a paclitaxel-eluting balloon. | 2009 | 19490359 |
| endothelialization of nonapposed stent struts located over the origin of a side branch: results with different carbofilm-coated stents. | to evaluate the degree of endothelialization of the nonapposed struts located at the ostia of side branches. | 2009 | 19490356 |
| chromosomal assignment of porcine pregnancy-associated glycoprotein gene family. | this study presents the chromosomal assignment of a multiple pregnancy-associated glycoprotein (pag) gene family in the domestic pig (ppag). the ppag locus was identified by physical mapping (fluorescent in situ hybridisation-fish; with various probes), and additionally confirmed by southern hybridisation of ppag amplicons using laser microdissected sus scrofa chromosome 1 (ssc1), as genomic templates. various ppag probes were produced with the use of diverse identified templates: ppag1-6, -8, - ... | 2010 | 19487088 |
| isolation and fluorescence spectrum of cardiac myosin from pig heart. | cardiac myosin is the most abundant and bioactive protein presented in heart tissue. in this work, a simple method was described for preparation of high purity cardiac myosin for further research. with the use of a domestic pig left ventricle as the starting tissue, this method yielded 4.5 mg myosin per gram of wet tissue with a specific activity of 0.293 u/mg. the purification factor was 4.9-fold with an activity recovery of 42.1%. in addition, the investigation of fluorescence spectrum shown t ... | 2009 | 19475499 |
| receptor activator of nuclear factor kappa b ligand in an experimental intervertebral disc degeneration. | this study was designed to clarify the role of the receptor activator of nuclear factor kappa b ligand (rankl) in the process of discus degeneration and spondylarthrosis. it was hypothesized that experimental discus lesion would initiate not only local bone remodelling but also increased osteoclast formation on a location remote to the injury site due to altered spinal biomechanics. it was speculated that these changes in vertebral bone remodelling could be reflected in an increased rankl expres ... | 2009 | 19473572 |
| usefulness of mri to differentiate between temporary and long-term coronary artery occlusion in a minimally invasive model of experimental myocardial infarction. | the surgical technique employed to determine an experimental ischemic damage is a major factor in the subsequent process of myocardial scar development. we set out to establish a minimally invasive porcine model of myocardial infarction using cardiac contrast-enhanced magnetic resonance imaging (ce-mri) as the basic diagnostic tool. twenty-seven domestic pigs were randomized to either temporary or permanent occlusion of the left anterior descending artery (lad). temporary occlusion was achieved ... | 2009 | 19472001 |
| trichuris suis and trichuris trichiura are different nematode species. | in this paper, a morphological and biometrical study by optical microscopy and scanning electronic microscopy (sem) of trichuris suis isolated from different hosts (sus scrofa domestica and sus scrofa scrofa) and trichuris trichiura isolated from chimpanzee, has been carried out. our results demonstrate the existence of typical pericloacal papillae in both species. biometrical parameters of t. suis and t. trichiura overlapped but males and females of t. trichiura tended to be shorter and thinner ... | 2009 | 19467214 |
| comparative analysis of solar radiation-induced cellular damage between ex vivo porcine skin organ culture and in vitro reconstructed human epidermis. | reconstructed human epidermis models (rhe) constitute an innovative alternative to study phototoxicity and photoprotection in the cosmetic industry. however, little information is currently available concerning the harmful effects of solar-simulated radiation (ssr) in these in vitro skin models. in this study, the phototoxic effects of a single acute ssr dose of 275 kj m(-2) were evaluated in a validated rhe model (from skinethic), and were compared with those obtained from an ex vivo skin organ ... | 2009 | 19467030 |
| imaging of the midpalatal suture in a porcine model: flat-panel volume computed tomography compared with multislice computed tomography. | an investigation was conducted to compare the image quality of prototype flat-panel volume computed tomography (fpvct) and multislice computed tomography (msct) of suture structures. | 2009 | 19464211 |
| meat juice as diagnostic sample for virological and serological diagnosis of classical swine fever. | the objective of this paper was to assess if meat juice is a suitable substrate for virological and serological diagnosis of classical swine fever (csf). fifty-six domestic pigs and 21 wild boars experimentally vaccinated and/or infected as well as 129 field samples from wild boars were involved in this study. meat juice from diaphragm, forequarter and hindquarter was used for investigations. csfv and viral rna were detected in meat juice between days 5 and 21 post infection (pi). animals which ... | 2009 | 19462640 |
| molecular taxonomy, phylogeny and biogeography of nematodes belonging to the trichinella genus. | studying parasites of the genus trichinella provides scientists of today many advantages. this is a group of zoonotic nematodes that circulates freely among wildlife hosts with one in particular, trichinella spiralis that is exceptionally well adapted to domestic swine. recent reports suggest that human infections from hunted animals are on the rise worldwide and numerous countries still experience problems with t. spiralis in their domestic food supplies. trichinella is a genus whose members ar ... | 2009 | 19460327 |
| prevention of vasa vasorum neovascularization attenuates early neointima formation in experimental hypercholesterolemia. | vasa vasorum (vv) neovascularization is a key feature of early atherosclerosis and adds substantial endothelial exchange-surface to the coronary vessel wall. thus, it is conceivable that vv neovascularization favors the entry of pro-inflammatory and pro-atherosclerotic blood components into the coronary vessel wall. we sought to investigate the effects of thalidomide (th), a potent anti-angiogenic drug on vasa vasorum (vv) neovascularization, vessel wall inflammation, and neointima formation in ... | 2009 | 19458984 |
| wound healing and the immune response in swine treated with a hemostatic bandage composed of salmon thrombin and fibrinogen. | we investigated the inflammatory response in pigs exposed to salmon fibrinogen/thrombin dressings. animals were exposed to the material in 3 ways: (a) thrombin and fibrinogen were injected intravenously, (b) dual full-thickness skin lesions were surgically created on the dorsal aspect of the swine and treated with the fibrinogen/thrombin bandage and a commercial bandage or (c) a fibrinogen/thrombin bandage was inserted through an abdominal incision into the peritoneal cavity. blood was collected ... | 2009 | 19449202 |
| comparison of vascularized osteoperiosteal femur flaps and nonvascularized femur grafts for reconstruction of mandibular defects: an experimental study. | the aim of this study was to compare the vascularized osteoperiosteal femur flaps (vffs) and the nonvascularized femur grafts (nvfgs) for reconstruction of the mandibular defects of pigs. | 2009 | 19446201 |
| recording diffusion responses from contralateral intercostal muscles after stimulus-triggered electromyography: refining a tool for the assessment of thoracic pedicle screw placement in an experimental porcine model. | a new stimulus-triggered electromyography (emg) test for detecting stimulus diffusion to contralateral intercostal muscles during thoracic pedicle screw placement was assessed in a porcine model. | 2009 | 19444052 |
| endemic hepatitis e in two nordic countries. | antibodies against hepatitis e virus (anti-hev) were found in 248 swedish and danish patients between 1993 and 2007. most patients were symptomatic and tested for anti-hev due to travel abroad. among patients with known country of infection, most were infected in asia, mainly on the indian subcontinent. however, 29 patients were infected in europe, nine of these had hev igm and/or hev rna in serum. in sera from 65 of 141 tested patients hev rna could be detected, and 63 strains could be typed by ... | 2009 | 19442399 |
| detection of hepatitis e virus in wild boars of rural and urban regions in germany and whole genome characterization of an endemic strain. | hepatitis e is an increasingly diagnosed human disease in central europe. besides domestic pigs, in which hepatitis e virus (hev) infection is highly prevalent, wild boars have been identified as a possible source of human infection. in order to assess the distribution of hev in the wild boar population of germany, we tested liver samples originating from different geographical regions for the presence of the hev genome and compared the detected sequences to animal and human hev strains. | 2009 | 19442307 |
| an integrated rh map of porcine chromosome 10. | whole genome radiation hybrid (wg-rh) maps serve as "scaffolds" to significantly improve the orientation of small bacterial artificial chromosome (bac) contigs, order genes within the contigs and assist assembly of a sequence-ready map for virtually any species. here, we report the construction of a porcine: human comparative map for pig (sus scrofa) chromosome 10 (ssc10) using the imnprh2(12,000-rad) porcine wg-rh panel, integrated with the imprh(7000-rad) wg-rh, genetic and bac fingerprinted c ... | 2009 | 19426492 |
| pure 'natural orifice transluminal endoscopic surgery' for transvaginal nephrectomy in the porcine model. | to determine the technical feasibility and reproducibility of pure natural orifice transluminal endoscopic surgery (notes) transvaginal nephrectomy using notes-specific instrumentation, with no transabdominal assistance. | 2009 | 19426194 |
| cadaveric volatile organic compounds released by decaying pig carcasses (sus domesticus l.) in different biotopes. | forensic entomology uses pig carcasses to surrogate human decomposition and to investigate the entomofaunal colonization. insects communicate with their environment through the use of chemical mediators, which in the case of necrophagous insects, may consist in the cadaveric volatile organic compounds (vocs) released by the corpse under decomposition. previous studies have focused on cadaveric vocs released from human corpses. nevertheless, studies on human corpses are restricted for many reason ... | 2009 | 19423246 |
| recombinant antigen targets for serodiagnosis of african swine fever. | african swine fever (asf) is an infectious and economically important disease of domestic pigs. there is no vaccine, and so reliable diagnosis is essential for control strategies. the performance of four recombinant asf virus (asfv) protein (pk205r, pb602l, p104r, and p54)-based enzyme-linked immunosorbent assays (elisas) was evaluated with european porcine field sera that had been established by office international des epizooties (oie)-approved tests to be asfv negative (n = 119) and asfv posi ... | 2009 | 19420186 |
| relaxin and maternal lactocrine programming of neonatal uterine development. | in mammals, including the pig (sus scrofa domesticus), structural patterning and functional programming of uterine tissues involve events that occur shortly after birth. porcine endometrial development between birth (postnatal day 0 [pnd 0]) and pnd 15 is estrogen receptor (er) dependent and estrogen sensitive. the endometrium is relaxin (rlx) receptor (rxfp1) positive and eralpha negative at birth. uterine expression of rxfp1 and eralpha, detectable by pnd 2, increases with age from pnd 0 to 14 ... | 2009 | 19416179 |
| pre-natal stress amplifies the immediate behavioural responses to acute pain in piglets. | pre-natal stress (pns) or undernutrition can have numerous effects on an individual's biology throughout their lifetime. some of these effects may be adaptive by allowing individuals to tailor their phenotype to environmental conditions. here we investigated, in the domestic pig sus scrofa, whether one possible consequence of a predicted adverse environment could be altered pain perception. the behavioural response of piglets to the surgical amputation ('docking') of their tail or a sham procedu ... | 2009 | 19411272 |
| porcine hypothalamic aromatase cytochrome p450: isoform characterization, sex-dependent activity, regional expression, and regulation by enzyme inhibition in neonatal boars. | domestic pigs have three cyp19 genes encoding functional paralogues of the enzyme aromatase cytochrome p450 (p450arom) that are expressed in the gonads, placenta, and preimplantation blastocyst. all catalyze estrogen synthesis, but the gonadal-type enzyme is unique in also synthesizing a nonaromatizable biopotent testosterone metabolite, 1oh-testosterone (1oh-t). p450arom is expressed in the vertebrate brain, is higher in males than females, but has not been investigated in pigs, to our knowledg ... | 2009 | 19403926 |
| influence of sex on the meiotic segregation of a t(13;17) robertsonian translocation: a case study in the pig. | comparison of male versus female meiotic segregation patterns for robertsonian translocation (rt) carriers with similar genetic background has rarely been reported in mammalian species. | 2009 | 19403564 |
| feral swine contact with domestic swine: a serologic survey and assessment of potential for disease transmission. | feral swine (sus scrofa) are present in 38 of the 50 united states, and their populations continue to expand. domestic swine are widely regarded as vulnerable to diseases harbored by feral swine. our objectives were to determine antibody prevalence for selected pathogens in texas feral swine populations and identify contact events between feral and domestic swine. overall prevalence of antibodies against brucellosis and pseudorabies virus was 11% and 30%, respectively. antibodies to porcine repr ... | 2009 | 19395751 |
| occurrence and pathways of manure-borne 17beta-estradiol in vadose zone water. | the hormone 17beta-estradiol (e2) can cause endocrine disruption in sensitive species at part per trillion concentrations. the persistence and transport pathways of manure-borne e2 in agricultural soils were determined by comparing its occurrence with the transfer of water and the transport of non-sorbing fluorobenzoic acid (fba) tracers. this comparison was done using capillary wick lysimeters installed 0.61m beneath three corn (zea mays l.) plots that receive swine (sus scrofa domesticus) manu ... | 2009 | 19394677 |
| effect of recipient breed on delivery rate of cloned miniature pig. | the miniature pig is regarded as a better organ donor breed for xenotransplantation than other pig breeds because the size of their organs is similar to that of humans. to improve efficiency of cloned miniature pig production, we analysed the effect of breed difference between donor cells and embryo recipients on pregnancy rate and delivery rate. cloned porcine embryos derived from domestic or miniature pig donor cells were transferred to domestic or miniature recipient pigs. delivery rate was s ... | 2009 | 19393119 |
| [(18)f]fluoroacetate is not a functional analogue of [(11)c]acetate in normal physiology. | [(11)c]acetate (c-ac) is a general pet tracer of cellular carbon flux and useful for clinical imaging in heart disease as well as prostate cancer and other tumours. c-ac has a high (70%) whole-body extraction fraction, proportional to blood flow in many organs. trapping is related to organ-specific enzymatic activation and formation of [(11)c]-acetyl-coa, the fate of which has been well characterized. due to the logistic challenges with c-ac, 2-[(18)f]fluoroacetate (f-ac) has been proposed as a ... | 2009 | 19387639 |
| distribution of cocaine- and amphetamine-regulated transcript in the hippocampal formation of the guinea pig and domestic pig. | this study provides a detailed description concerning the distribution of cocaineand amphetamine-regulated transcript (cart) subunits - cart(61-102) and rhcart(28-116) - in the hippocampal formation (hf) of the guinea pig and domestic pig, focussing on the dentate gyrus (dg) and hippocampus proper (hp). although in both studied species cart-immunoreactive (cart-ir) neuronal somata and processes were present generally in the same layers, some species-specific differences were still found. in the ... | 2009 | 19384826 |
| video-assisted lung resection using radiofrequency ablation in a porcine model. | the aim of this study was to assess the feasibility, efficacy, and safety of video-assisted lingula resection using radiofrequency ablation (rfa) with internally cooled electrodes in a porcine model. | 2009 | 19376530 |
| multipolar radiofrequency ablation in controlling hemorrhage from blunt liver trauma. | the aim of this study is to investigate the use of multipolar radiofrequency (rf) ablation with internally cooled electrodes to control hemorrhage percutaneously from blunt liver trauma. | 2009 | 19371528 |
| total gastrectomy causes a sustained, long-term elevation of somatostatin in plasma, independent of the mode of reconstruction in pigs. | the long-term effects of gastrectomy and various reconstructions of the gastrointestinal tract on fasting plasma levels of gastrointestinal hormones known to contribute to the control of gastrointestinal motor function were evaluated in pigs. | 2009 | 19368132 |
| jejunal pouch reconstruction but not preservation of duodenal passage after total gastrectomy reduces plasma cholecystokinin and pancreatic polypeptide long term in pigs. | the long-term effects of reconstructions of the gastrointestinal tract after gastrectomy on plasma levels of gastrointestinal hormones that contribute to food intake controls were evaluated. | 2009 | 19368131 |
| intra-abdominal pressure development after different temporary abdominal closure techniques in a porcine model. | decompressive laparotomy followed by temporary abdominal closure (tac) is an established prophylaxis and treatment for abdominal compartment syndrome. the herein presented study aimed at the comparison of volume reserve capacity and development of intra-abdominal hypertension after forced primary abdominal closure and different tac techniques in a porcine model. | 2009 | 19359923 |
| porcine cd18 mediates actinobacillus pleuropneumoniae apxiii species-specific toxicity. | actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, produces apx toxins that are recognized as major virulence factors. recently, we showed that apxiiia-cytotoxic activity specifically targets sus scrofa leukocytes. since both ltxa from aggregatibacter actinomycetem comitans (aggressive periodontitis in humans) and lkta from mannheimia haemolytica (pneumonia in ruminants) share this characteristic, respectively towards human and ruminant leukocytes, and because both ... | 2009 | 19356397 |
| modulation of porcine (sus scrofa domestica) and pheasant (phasianus colchicus) carbonyl reducing enzymes by anthelmintic therapy with flubendazole. | flubendazole (flu) is a widely administered benzimidazole anthelmintic indicated for the control of parasitic diseases in farm animals including pigs and pheasants. this study was designed to test the biotransformation of flu in control animals and animals treated with flu in recommended therapeutic doses. the activities of several pheasant and porcine hepatic and intestinal carbonyl reducing enzymes and their modulation by flu were also studied. twelve adult pheasant hens, approximately 1 year ... | 2008 | 19356067 |
| imaging sequences for intraoperative mr-guided laparoscopic liver resection in 1.0-t high field open mri. | the aim of this study was to identify suitable interactive (dynamic) magnetic resonance (mr) sequences for real-time mr-guided liver dissection in a 1.0-t high field open mri system. four dynamic sequences encompassing balanced steady state free precession (bssfp), t1w gradient echo (gre), t2w gre and t2w fast spin echo (fse) were analysed regarding the image quality, artefact susceptibility and the performance of snr and cnr. the t2w fse sequence (1.5 s/image) was considered superior because of ... | 2009 | 19350246 |
| evaluation of endoscopic-ultrasound-guided celiac ganglion irradiation with iodine-125 seeds: a pilot study in a porcine model. | implantation of iodine-125 ( (125)i) seeds under the guidance of endoscopic ultrasonography (eus) has been proved to be a safe alternative treatment option for advanced pancreatic cancer. the main purpose of this study was to evaluate the feasibility and safety of eus-guided radiation of the celiac ganglia with (125)i seeds in a porcine model. | 2009 | 19340740 |
| complex porcine model of atherosclerosis: induction of early coronary lesions after long-term hyperlipidemia without sustained hyperglycemia. | the incidence of coronary artery disease (cad) is still increasing in industrialized countries and it is even higher in diabetic patients. for experimental studies investigating the pathophysiology of cad, the use of an animal model comparable with the pathological situation in patients is crucial. | 2009 | 19340354 |
| portal vein embolization with radiolabeled polyvinyl alcohol particles in a swine model: hepatic distribution and implications for pancreatic islet cell transplantation. | the distribution of radiolabeled polyvinyl alcohol microspheres (pvams) when infused into the portal vein of domestic swine was investigated, with the purpose of assessing implications for pancreatic islet cell transplantation. pvams measuring 100-300 microm (contour se) and labeled with (99m)tc were infused into the main portal vein of 12 swine, with intermittent portal venous pressure measurements. the infusion catheter was introduced antegradely via direct or indirect cannulation of the porta ... | 2009 | 19330373 |
| normal profiles for deciduous dental eruption in domestic piglets: effect of sow, litter, and piglet characteristics. | the deciduous dentition of the domestic pig is comprised of 28 teeth (2 x incisors 3/3, canine 1/1, premolars 3/3, molars 0/0). the timing and sequence of deciduous dental eruption were determined from oral exams on 233 yorkshire piglets from 0 to 5 wk of age. eruption occurred sooner in gilts for all molariform premolars (p(3), p(4), and p(4), p < 0.01) and first incisor, i(1) (p = 0.004). birth weight influenced eruption for all teeth except i(1) (i(1), p(3), p(3), p(4), and p(4); p < 0.01), w ... | 2009 | 19329477 |
| the genome sizes of megabats (chiroptera: pteropodidae) are remarkably constrained. | it has long been recognized that bats and birds contain less dna in their genomes than their non-flying relatives. it has been suggested that this relates to the high metabolic demands of powered flight, a notion that is supported by the fact that pterosaurs also appear to have exhibited small genomes. given the long-standing interest in this question, it is surprising that almost no data have been presented regarding genome size diversity among megabats (family pteropodidae). the present study ... | 2009 | 19324635 |
| mitochondrial dna sequence variations in some italian wild boar populations. | in order to investigate the relationships between italian wild boar and major pig breeds, we studied the genetic variability of four wild boar populations in italy (arezzo, pisa, parma, bergamo) using a 533-bp fragment of the mitochondrial control region. sixty-nine wild boar samples were analysed, allowing the identification of 10 distinct haplotypes, which involve a total of 15 single nucleotide polymorphisms. phylogenetic and network analyses were performed also considering several sequences ... | 2009 | 19320773 |
| non-iterative variance component estimation in qtl analysis. | in variance component quantitative trait loci (qtl) analysis, a mixed model is used to detect the most likely chromosome position of a qtl. the putative qtl is included as a random effect and a method is needed to estimate the qtl variance. the standard estimation method used is an iterative method based on the restricted maximum likelihood (reml). in this paper, we present a novel non-iterative variance component estimation method. this method is based on henderson's method 3, but relaxes the c ... | 2009 | 19320767 |
| comparison of electrically induced flare response patterns in human and pig skin. | we compared the characteristics of neurogenic flare responses in human and pig skin to establish a translational research animal model. | 2009 | 19319479 |
| molecular magnetic resonance imaging of myocardial perfusion with ep-3600, a collagen-specific contrast agent: initial feasibility study in a swine model. | cardiac magnetic resonance (mr) perfusion imaging during the first pass after intravenous administration of extracellular contrast agents is hampered by the spatial and temporal resolution achievable and by the artifacts seen in ultrafast mr imaging. furthermore, time-consuming quantitative data analysis is often added. the use of molecular mr imaging with a target-specific contrast agent with perfusion-dependent binding to myocardium may enable prolonged visualization of perfusion defects and t ... | 2009 | 19307474 |
| mouse x pig chimeric antibodies expressed in baculovirus retain the same properties of their parent antibodies. | the development of hybridoma and recombinant dna technologies has made it possible to use antibodies against cancer, autoimmune disorders, and infectious diseases in humans. these advances in therapy, as well as immunoprophylaxis, could also make it possible to use these technologies in agricultural species of economic importance such as pigs. porcine reproductive and respiratory syndrome virus (prrsv) is an arterivirus causing very important economic losses to the industry. passive transfer of ... | 2009 | 19301248 |
| wireless video capsule enteroscopy in preclinical studies: methodical design of its applicability in experimental pigs. | the aim of this project was to develop a methodology to introduce wireless video capsule endoscopy in preclinical research. five mature female pigs (sus scrofa domestica) were selected for the study. capsule endoscopes (the endocapsule system; olympus) were introduced into the duodenum endoscopically in each of the animals. the life span of batteries (i.e., total time of endoscopy recording) was 487-540 min (median 492 min). the capsule endoscope reached the cecum during enteroscopy once (after ... | 2010 | 19294508 |
| a family of splice variants of cstf-64 expressed in vertebrate nervous systems. | alternative splicing and polyadenylation are important mechanisms for creating the proteomic diversity necessary for the nervous system to fulfill its specialized functions. the contribution of alternative splicing to proteomic diversity in the nervous system has been well documented, whereas the role of alternative polyadenylation in this process is less well understood. since the cstf-64 polyadenylation protein is known to be an important regulator of tissue-specific polyadenylation, we examin ... | 2009 | 19284619 |
| comparison of two different paclitaxel-coated balloon catheters in the porcine coronary restenosis model. | drug-eluting balloon (deb) catheters coated with paclitaxel in a water-soluble matrix have shown beneficial effects in the treatment and prevention of restenosis in the porcine coronary overstretch model and in clinical trials. adherence of paclitaxel, same dose, on another recently introduced coated percutaneous coronary intervention (pci) catheter (dior) is mediated by a roughened balloon surface. only scarce experimental and clinical data has been published on the new coating method. the aim ... | 2009 | 19280084 |
| giardia genotypes in pigs in western australia: prevalence and association with diarrhea. | little is known of the prevalence of giardia species and genotypes in pre- and post-weaned domestic pigs. in the present study, a total of 297 pig faecal samples were screened for the presence of giardia by pcr and genotyped. an overall prevalence of 31.1% (90/289) (25.8, 36.5 ci) was detected. giardia was detected in 17% (23/123) (11.8-25.6 ci) of pre-weaned piglet faecal samples and 41% (64/156) (33.3-48.7 ci) post-weaned faecal samples analysed. sequence analysis identified assemblage a and e ... | 2009 | 19271283 |
| the association between central venous pressure, pneumoperitoneum, and venous carbon dioxide embolism in laparoscopic hepatectomy. | laparoscopic hepatectomy (lh) is increasingly used. however, the safety and outcomes of lh have yet to be elucidated. the risk of venous gas embolism is increased during liver parenchymal transection. this risk may be increased with positive pressure carbon dioxide (co(2)) pneumoperitoneum (pp). this may be exacerbated further when low central venous pressure (cvp) anesthesia is used to minimize hemorrhage during liver resection. | 2009 | 19266234 |
| cysticercosis of soft tissue. | cysticercosis is a systemic illness caused by dissemination of the larval form of the pork tapeworm, taenia solium. a high prevalence has been reported from the developing countries because of the co-existence of poor sanitary conditions and domestic pig raising. human cysticercosis occurs when eggs are ingested via faecal-oral transmission from a tapeworm host. the human then becomes an accidental intermediate host, with development of cysticerci within organs. cysticercosis is a preventable fa ... | 2009 | 19260577 |
| animal evolution during domestication: the domesticated fox as a model. | we review the evolution of domestic animals, emphasizing the effect of the earliest steps of domestication on its course. using the first domesticated species, the dog (canis familiaris), for illustration, we describe the evolutionary peculiarities during the historical domestication, such as the high level and wide range of diversity. we suggest that the process of earliest domestication via unconscious and later conscious selection of human-defined behavioral traits may accelerate phenotypic v ... | 2009 | 19260016 |
| effect of betaine supplementation on power performance and fatigue. | the purpose of this study was to examine the efficacy of 15 days of betaine supplementation on muscle endurance, power performance and rate of fatigue in active college-aged men. | 2009 | 19250531 |
| effects of streptozotocin-induced diabetes in domestic pigs with focus on the amino acid metabolism. | streptozotocin (stz) given intravenously destroys pancreatic beta cells and is widely used in animal models to mimic type 1 diabetes. the effects of stz on the clinical state of health and metabolism were studied in six high health certified domestic pigs weighing 19+/-1.3 kg at the start of the experiment. a single stz dose of 150 mg/kg of body weight successfully induced hyperglycaemia and alterations in amino acid metabolism. within 9 h after stz administration, the blood glucose values fell ... | 2009 | 19246503 |
| the effects of fasting and general anesthesia on serum chemistries in kcg miniature pigs. | investigators are obligated to optimize the perioperative care of experimental animals, but little is known about the effects of anesthesia and surgery on serum chemistries in kcg pigs. the objective of this study was to examine the influence of fasting and surgery under general anesthesia on 27 serum chemistries in kcg miniature pigs to improve management. crossbred kcg minipigs were used at a mean of 12.3 mo of age (range, 8.6 to 14.9) and 33.4 kg of body weight (range, 24.0 to 40.2). serum ch ... | 2009 | 19245748 |
| isolate designation and characterization of toxoplasma gondii isolates from pigs in the united states. | pigs are considered to be the most important meat source of toxoplasma gondii for humans in the united states. in the present study, 168 t. gondii isolates (designated tgpgus15-182) from various sources were genotyped using 10 polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) markers (sag1, sag2, sag3, btub, gra6, c22-8, c29-2, l358, pk1, and apico). genotyping data from an additional 14 isolates collected from t. gondii-infected pigs in maryland were included for ana ... | 2009 | 19245283 |
| a stochastic model to quantify the risk of introduction of classical swine fever virus through import of domestic and wild boars. | classical swine fever (csf) is a disease of pigs that imposes major hardship on the industry of infected regions. the recent history of csf epidemics suggests that animal movements remain the main source of csf virus (csfv) infection for susceptible populations in europe. this study presents an assessment of the risk of introducing csfv into spain through the importation of live susceptible animals. results suggest that, if prevailing conditions persist, introduction of csfv into spain is likely ... | 2009 | 19243649 |
| phase-contrast mri-based elastography technique detects early hypertensive changes in ex vivo porcine aortic wall. | to measure the elastic properties of ex vivo porcine aortas in control and hypertensive groups using a phase contrast magnetic resonance imaging (mri)-based elastography technique. | 2009 | 19243040 |
| epinephrine reduces cerebral perfusion during cardiopulmonary resuscitation. | epinephrine has been the primary drug for cardiopulmonary resuscitation (cpr) for more than a century. the therapeutic rationale was to restore threshold levels of myocardial and cerebral blood flows by its alpha1 (alpha1) and alpha2 (alpha2)-adrenergic agonist vasopressor actions. on the basis of coincidental observations on changes in microvascular flow in the cerebral cortex, we hypothesized that epinephrine selectively decreases microvascular flow. | 2009 | 19242339 |
| percutaneous left ventricular assist in ischemic cardiac arrest. | ischemic cardiac arrest represents a challenge for optimal emergency revascularization therapy. a percutaneous left ventricular assist device (lvad) may be beneficial. | 2009 | 19242324 |
| intraindividual comparison of image quality in mr urography at 1.5 and 3 tesla in an animal model. | experimental evaluation of image quality of the upper urinary tract in mr urography (mru) at 1.5 and 3 tesla in a porcine model. | 2008 | 19238642 |
| [molecular epidemiology of hepatitis e virus in hungary: endemic, food-borne zoonosis]. | hepatitis e virus (hev) is one of a common cause of acute, fecally transmitted hepatitis in developing countries. identification of hev in indigenous human infection and in domestic pig raises the possibility that hev infection is also a zoonosis. | 2009 | 19228570 |
| characterization and zoonotic potential of endemic hepatitis e virus (hev) strains in humans and animals in hungary. | hepatitis e virus (hev) is a common cause of acute, fecally transmitted hepatitis in developing countries. identification of hev in indigenous human infection and in domestic pig raising the possibility that hev infection is also a zoonosis. objectives/study design: molecular detection and epidemiology of hev in humans (south-east hungary) with acute hepatitis and in domestic (pig, cattle) and wild (boar and roe-deer) animals (countrywide) by elisa and rt-pcr. | 2009 | 19217346 |
| african swine fever virus. | african swine fever virus (asfv) is a large, intracytoplasmically-replicating dna arbovirus and the sole member of the family asfarviridae. it is the etiologic agent of a highly lethal hemorrhagic disease of domestic swine and therefore extensively studied to elucidate the structures, genes, and mechanisms affecting viral replication in the host, virus-host interactions, and viral virulence. increasingly apparent is the complexity with which asfv replicates and interacts with the host cell durin ... | 2009 | 19216435 |
| endoscopic closure of the natural orifice transluminal endoscopic surgery (notes) access site to the peritoneal cavity by means of transmural resorbable sutures: an animal survival study. | endoscopic closure of the transgastric access site is still a critical area of active research and development into natural orifice transluminal surgery (notes). to date, no endoscopic technique has utilized resorbable transmural sutures for closure of the notes gastrostomy. | 2009 | 19214896 |
| effects of stomach inflation on haemodynamic and pulmonary function during spontaneous circulation in pigs. | stomach inflation during mask ventilation is frequent, but the effects on haemodynamic and pulmonary function are unclear. we evaluated the effects of stomach inflation on haemodynamic and pulmonary function during spontaneous circulation in a porcine model. | 2009 | 19211181 |
| expression of vascular endothelial growth factor receptors coincide with blood vessel in-growth and reactive bone remodelling in experimental intervertebral disc degeneration. | to analyze immunohistochemically the localization of the vegf receptors in experimental intervertebral disc degeneration tissues in a pig model. | 2008 | 19210865 |
| retrograde flush following warm ischemia in the non-heart-beating donor results in superior graft performance at reperfusion. | the use of non-heart-beating donors (nhbd) has been propagated as an alternative to overcome the scarcity of pulmonary grafts. the presence of postmortem thrombi, however, is a concern for the development of primary graft dysfunction. in this isolated lung reperfusion study, we looked at the need and the best route of preharvest pulmonary flush. | 2009 | 19201425 |
| initial experimental evaluation of wireless capsule endoscopes in the bladder: implications for capsule cystoscopy. | cystoscopy remains one of the most important diagnostic procedures for the lower urinary tract. wireless capsule endoscopy was introduced in the 1990s but use to date is limited to gastroenterology. | 2009 | 19201077 |
| open versus laparoscopic retroperitoneal lymph node dissection: assessing adequacy of dissection in a porcine model. | laparoscopic retroperitoneal lymph node dissection (l-rplnd) is emerging as a viable alternative to traditional open retroperitoneal lymph node dissection (o-rplnd). despite numerous reports confirming clinical oncologic equivalency between the two approaches, however, concerns still remain over the adequacy of laparoscopic dissection. we therefore sought to compare the completeness of dissection between o-rplnd and l-rplnd in a porcine model. | 2009 | 19193133 |
| population dynamics of swine influenza virus in farrow-to-finish and specialised finishing herds in the netherlands. | influenza virus infections with subtypes h1n1, h3n2 and h1n2 are very common in domestic pigs in europe. data on possible differences of population dynamics in finishing pigs in farrow-to-finish herds and in specialised finishing herds are, however, scarce. the presence of sows and weaned piglets on the same premises may, however, affect the exposure of finishing pigs to influenza viruses. in a longitudinal study on 14 farrow-to-finish herds and 15 finishing herds, groups of pigs were followed b ... | 2009 | 19181461 |
| time dependent vascular and myocardial responses of a second generation, small vessel, paclitaxel-eluting stent platform. | the purpose of this study was to evaluate the time-dependent vascular and myocardial responses to a second-generation, small vessel (< or =2.5 mm) paclitaxel-eluting stent (pes) platform. | 2009 | 19180652 |
| salmonella, escherichia coli o157:h7 and e. coli biotype 1 in a pilot survey of imported and new zealand pig meats. | a pilot survey for the pathogens salmonella and escherichia coli o157:h7, and e. coli biotype 1 was conducted on 100 new zealand-produced (domestic) pig carcasses and 110 imported pig meat samples over an 8-month period to assess the likelihood of introduction of novel pathogen strains into new zealand (nz), and as a guide for development of a domestic pork national microbiological database programme. salmonella was not isolated from domestic pig carcasses or from pig meat imported from canada a ... | 2009 | 19171260 |
| in vivo performance of selective electron beam-melted ti-6al-4v structures. | highly porous titanium structures are widely used for maxillofacial and orthopedic surgery because of their excellent mechanical properties similar to those of human bone and their facilitation of bone ingrowth. in contrast to common methods, the generation of porous titaniumproducts by selective electron beam melting (sebm), an additive manufacturing technology, overcomes difficulties concerning the extreme chemical affinity of liquid titanium to atmospheric gases which consequently leads to st ... | 2010 | 19165781 |
| a novel tgf-beta antagonist speeds reepithelialization and reduces scarring of partial thickness porcine burns. | scar formation after thermal injury is common and results in significant aesthetic and functional impairment. transforming growth factor beta (tgf-beta) plays a significant role in scar formation. we tested the hypothesis that a novel tgf-beta peptantagonist would reduce scar formation and wound contraction in partial thickness burns by using a randomized controlled experiment. the subjects include two domestic pigs (20-25 kg). forty burns were created on the animal's dorsum using an aluminum ba ... | 2009 | 19165091 |
| expanding the versatility of cardiac pet/ct: feasibility of delayed contrast enhancement ct for infarct detection in a porcine model. | it has recently been suggested that, similar to mri, ct can be used to detect infarcts at high resolution by delayed myocardial contrast enhancement. in cardiac pet/ct, this ability to detect infarcts may increase the versatility and integrative potential of pet and ct study components. we sought to determine the feasibility of delayed ct-enhancement in the pet/ct environment and compared it with pet-defined rest perfusion for the measurement of infarct size. | 2009 | 19164240 |
| measurements of subcutaneous tissue po2 reflect oxygen metabolism of the small intestinal mucosa during hemorrhage and resuscitation. an experimental study in pigs. | the first tissues to be deprived of perfusion and oxygenation in a hypovolemic situation and the last ones to be reperfused are the subcutaneous tissue and the gastrointestinal mucosa. we hypothesized that measurements of subcutaneous tissue gases and ph might reflect simultaneous changes in oxygenation of the intestinal mucosa. the aim of this study was to evaluate tissue gases and ph as measures of tissue oxygenation and tissue oxygen metabolism in subcutaneous and intestinal tissues simultane ... | 2009 | 19155629 |
| pretreatment with low-energy shock waves induces renal vasoconstriction during standard shock wave lithotripsy (swl): a treatment protocol known to reduce swl-induced renal injury. | to test the hypothesis that the pretreatment of the kidney with low-energy shock waves (sws) will induce renal vasoconstriction sooner than a standard clinical dose of high-energy sws, thus providing a potential mechanism by which the pretreatment sw lithotripsy (swl) protocol reduces tissue injury. | 2009 | 19154458 |
| development of a recombinant antigen-based elisa for the sero-detection of porcine lymphotropic herpesviruses. | xenotransplantation using pigs as donor species carries a risk for the activation of latent porcine herpesviruses and potential transmission to the human recipient. the porcine lymphotropic herpesviruses (plhv-1, -2, -3) are widespread in domestic pigs and closely related to the human gammaherpesviruses, epstein-barr virus and kaposi sarcoma herpesvirus, causing lymphoproliferative disorders. plhv-1 has been associated with a porcine post-transplantation lymphoproliferative disorder (ptld), affe ... | 2008 | 19152663 |