Publications
Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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study of the relation between tissue typing and occurrence of filariasis and its complications in egypt. | 1987 | 3320221 | |
retroperitoneal cyst of filarial origin. | 1987 | 3320023 | |
[finding of a case of filariasis probably native in the state of ceará]. | 1986 | 3317558 | |
scanning electron microscopic study of third-stage larva of wuchereria bancrofti and brugia malayi in thailand. | 1987 | 3313744 | |
aedes (finlaya) togoi theobald 1907, chanthaburi strain, a laboratory vector in studies of filariasis in thailand. | 1987 | 3313743 | |
filariasis in tak province, northwest thailand: the presence of subperiodic variant wuchereria bancrofti. | the microfilariae found in carriers at tak province, northwestern thailand were morphologically and morphometrically studied. it was found that the parasites conformed to that of w. bancrofti microfilaria. the microfilarial periodicity as determined from four carriers was found to be nocturnally (early evening) subperiodic type showing a distinct peak at 1800 hours. | 1987 | 3313738 |
development of brugia malayi in mongolian gerbils previously exposed to wuchereria bancrofti. | twelve mongolian gerbils, meriones unguiculatus, were infected with 100 third-stage larvae of wuchereria bancrofti. one month later these animals, along with 4 control animals, were given 100 third-stage larvae of brugia malayi. eleven of the 12 experimental animals and the 4 controls survived, and 8 of the experimental animals and all of the controls demonstrated microfilaremia after 3 months. the animals were killed at 6-months post-infection and examined for parasites. one w. bancrofti larva ... | 1987 | 3313736 |
[filariasis caused by wuchereria bancrofti cobbold, 1877 (nematoda: filaroidea). report of a case in cuba]. | 1987 | 3313564 | |
the silvered leaf monkey (presbytis cristata) as a model for human bancroftian filariasis. | 1987 | 3312807 | |
immunosuppression in clinical filariasis. | 1987 | 3311987 | |
prevalence survey of filariasis in two villages in chingleput district of tamil nadu. | 1987 | 3311986 | |
evaluation of specific humoral immune responses in human filariasis. | using the antigens prepared from adult worms of b. malayi and d. immitis, a total of 37 malayan and 150 bancroftian serum samples were analysed for the presence of filarial specific antibodies by counterimmunoelectrophoresis and indirect enzyme linked immunosorbent assay. it was observed that microfilaraemic cases do show good specific humoral immune responses against homologous as well as heterologous antigen. of the two antigens used, b. malayi adult antigen was found to be superior to d. immi ... | 1987 | 3311932 |
in vitro cultivation of third stage larvae of wuchereria bancrofti to the fourth stage. | third stage larvae of wuchereria bancrofti obtained from laboratory-infected mosquitoes grew and molted to the fourth stage in vitro. the culture medium which supported the best growth and development consisted of a 1:1 mixture (v/v) of two commercially available cell culture media, nctc 135 and iscove's modified dulbecco's medium supplemented with 10% human serum or plasma and an antibacterial/antimycotic mixture. cultures were incubated at 37 degrees c in an atmosphere of either 5% or 8% co2 i ... | 1987 | 3310688 |
igg antibody subclasses in human filariasis. differential subclass recognition of parasite antigens correlates with different clinical manifestations of infection. | the four subclasses of igg are distinct in structure, function, and degree of participation in the antibody response to complex antigens. looking for differential responsiveness of potential pathogenetic significance, we have analyzed both quantitatively and qualitatively the filaria-specific igg subclass responses of 20 patients with lymphatic filariasis presenting either with chronic lymphatic obstructive pathology and elephantiasis (cp) or with asymptomatic microfilaremia (mf). subclass-speci ... | 1987 | 3309059 |
factor influencing acceptance and non-acceptance to dec in a bancroftian endemic area. | 1986 | 3309041 | |
effectiveness of membrane feeding method in relation to development of filarial infective larvae in culex quinquefasciatus. | 1986 | 3309040 | |
filaria specific monoclonal antibodies for diagnosis. | 1986 | 3309039 | |
epidemiological study on lymphatic filariasis in an endemic zone of orissa. | 1986 | 3309037 | |
lymphatic filariasis: lymphocyte sub-populations in wuchereria bancrofti infection. | 1986 | 3309036 | |
in vitro maintenance and development of wuchereria bancrofti microfilariae. | 1986 | 3309035 | |
a filariasis survey among the migratory labourers at alwar, rajasthan. | 1986 | 3309034 | |
control of bancroftian filariasis in rural areas through selected treatment with diethylcarbamazine. | 1986 | 3309033 | |
control of filariasis in india. | 1986 | 3309032 | |
relative impact of integrated vector control strategy vis-a-vis conventional control strategy on bancroftian filariasis in pondicherry. | 1986 | 3309031 | |
detection and diagnostic utility of in vitro and in vivo released antigens in bancroftian filariasis. | 1986 | 3309030 | |
relevance of species specific filarial antigens for diagnosis. | 1986 | 3309026 | |
filarial chyluria: an immunological and renal function study. | 1987 | 3308835 | |
[epidemiological features of residual infection foci of filariasis in controlled areas and purifying measures]. | 1987 | 3308362 | |
[estimation of some entomological parameters in relation to the transmission of bancroftian filariasis]. | 1987 | 3308162 | |
[longitudinal surveillance in areas with bancroftian filariasis virtually eradicated in guizhou]. | 1987 | 3308161 | |
filariasis of the breast. | filariasis of the breast is usually seen in endemic areas. involvement may, however, present years after leaving an endemic area and be associated with circulating microfilariae. we describe the findings in a woman who developed a breast mass three years after a visit to her native india. | 1987 | 3307689 |
a survey of bancroftian filariasis in the dominican republic. | 1987 | 3305853 | |
[determination of circulating antigens in human filariasis by means of a modified sandwich enzyme-linked immunosorbent assay (ms-elisa) using monoclonal antibodies]. | 1987 | 3304699 | |
[studies on the role of residual microfilaremia in bancroftian filariasis transmission in controlled areas]. | 1987 | 3304654 | |
the disappearance of bancroftian filariasis from charleston, south carolina. | i suggest the hypothesis that bancroftian filariasis, endemic since the early days of slavery in charleston, south carolina, disappeared around 1930 by virtue of the long-term effects of a municipal sewerage-water system begun in the 1890s or thereabouts. these public works, originally intended to abate typhoid and related diseases, helped to eliminate filariasis by reducing the availability of polluted domestic waters which are the preferred breeding sites for the urban vector, culex quinquefas ... | 1987 | 3300389 |
efficiency of papain-treated microfilariae of wuchereria bancrofti (var. pacifica) as antigen for serodiagnosis of bancroftian filariasis in french polynesia. | papain-treated microfilariae of wuchereria bancrofti have been used as antigen for indirect fluorescent assay: 0% of non-endemic sera, 8% of healthy exposed polynesians, 48% of clinical patients and 96% of microfilaraemic subjects were positive by this test. the geometric mean titres were 22, 41, 147 and 605 respectively. untreated microfilariae were unsuitable for diagnostic purposes. dirofilaria immitis adult sections showed low reactivity, giving poor discrimination between non-endemic and mi ... | 1986 | 3299894 |
chromosome aberrations in leukocytes of filaria-infected indigenous inhabitants in the philippines. | in the course of genetic population surveys of a tribal group of the philippine negritos living on mindanao island, microfilariae (wuchereria bancrofti) were incidentally found on the microscopic slides for a cytogenetic investigation. structural chromosome aberrations in the cultured leukocytes from 19 filaria-infected and 22 uninfected subjects were studied. the frequencies of chromosome type aberrations such as dicentrics and chromosome breaks in the infected subjects were significantly highe ... | 1986 | 3298746 |
a monoclonal antibody-based enzyme immunoassay for detecting parasite antigenemia in bancroftian filariasis. | we evaluated a monoclonal antibody-based enzyme immunoassay for detecting soluble parasite antigen in sera collected in an area in south india endemic for wuchereria bancrofti. filarial antigen was detected in sera from 56 of 57 microfilaremic patients, 9 of 64 aminofilaremic patients with clinical filariasis, and 11 of 70 endemic controls. antigen was not detected in sera from patients from nonendemic areas who had a variety of other filarial and nonfilarial helminth infections. parasite antige ... | 1987 | 3298458 |
acute tropical pulmonary eosinophilia. characterization of the lower respiratory tract inflammation and its response to therapy. | although acute tropical pulmonary eosinophilia (tpe) is well recognized as a manifestation of filarial infection, the processes that mediate the abnormalities of the lung in tpe are unknown. to evaluate the hypothesis that the derangements of the lower respiratory tract in this disorder are mediated by inflammatory cells in the local milieu, we utilized bronchoalveolar lavage to evaluate affected individuals before and after therapy. inflammatory cells recovered from the lower respiratory tract ... | 1987 | 3298321 |
cellular unresponsiveness in patients with soluble circulating antigens in bancroftian filariasis. | 1987 | 3298028 | |
antibody responses to human lymphatic filarial parasites. | the lymphatic filarial parasites, brugia and wuchereria, continue to present an immunological puzzle, particularly with respect to the development of natural resistance or damaging disease. we have approached this question by examining humoral responses to a few defined antigens of selected interest from these parasites, using sera from each category in the spectrum of filarial disease. many antigens, such as the major adult surface protein of mr 29,000 (29k), appear to be recognized at all stag ... | 1987 | 3297556 |
the spectrum of disease in lymphatic filariasis. | lymphatic filariasis affects predominantly the poorer sector of a community, who can least afford to have the disease. according to an estimate by the world health organization in 1984, more than 90 million people are currently infected. it is postulated that the different disease manifestations of filariasis are caused by different host immune responses. an understanding of the clinical spectrum of lymphatic filariasis is essential for the effective treatment and control of the disease, and for ... | 1987 | 3297555 |
the wellcome trust lecture. inflammatory responses to filarial connective tissue parasites. | the inflammatory responses to lymphatic filariae and to onchocerca volvulus are reviewed with particular attention to evolutionary biology; inflammatory host spectrum; non-specific components; immunoregulation; immune evasion versus immunomodulation; chronic tissue damage and scarring and disease models. basic principles of pathogenesis are emphasized, comparisons drawn with schistosome infection, and critical items of missing information are highlighted. | 1987 | 3295688 |
a study of the antigen, antibody and immunecomplex levels in wuchereria bancrofti filariasis with reference to clinical status. | circulating antigens, antibodies to somatic and sheath components of microfilariae (mf) and immune complexes were determined in parallel in different categories of wuchereia bancrofti infection using, respectively, reverse indirect haemagglutination (riha), indirect haemagglutination (iha), indirect immunofluorescent (ifa) and polyethylene glycol (peg) precipitation assays. rabbit hyperimmune anti-w. bancrofti mf serum and mf homogenates were used as reagents. appreciable levels of antigens and ... | 1987 | 3295279 |
an analysis of in vitro b cell immune responsiveness in human lymphatic filariasis. | the immunoregulatory mechanisms involved in b cell function in patients with varying clinical manifestations of bancroftian filariasis were examined by studying the ability of peripheral blood mononuclear cells (pbmc) or pbmc subpopulations from patients with elephantiasis, asymptomatic microfilaremia (mf), and acute tropical pulmonary eosinophilia (tpe) to produce polyclonal and parasite-specific antibody in vitro, both spontaneously and in response to a mitogen (pwm) and to parasite antigen. w ... | 1987 | 3295043 |
[an epidemiological survey of filarial chyluria]. | 1988 | 3289747 | |
vector competence to wuchereria bancrofti in culex pipiens collected from the nile delta. | 1988 | 3286788 | |
evaluation of elisa and ihat in immunodiagnosis of bancroftian filariasis using delipidized l. carinii antigen. | 1988 | 3286786 | |
[upper extremity lymphedema in bancroftial filariasis]. | 1988 | 3286402 | |
ivermectin for the treatment of wuchereria bancrofti filariasis. efficacy and adverse reactions. | ivermectin treatment was evaluated for efficacy and side effects in 40 patients in south india who had microfilaremia and bancroftian filariasis. ivermectin was administered once orally at four dose levels (range, 25 to 200 micrograms/kg), and at each it was found to be completely effective in clearing blood microfilariae within five to 12 days. in most patients, microfilariae reappeared by three months; by six months the levels averaged 14% to 32% of pretreatment values in the four study groups ... | 1988 | 3285045 |
analysis, characterization, and diagnostic utility of filarial antigen fractions isolated from immune complexes in bancroftian filariasis. | circulating immune complexes isolated from clinical filarial patients' sera by 3% polyethylene glycol precipitation were analyzed by sds-polyacrylamide gel electrophoresis (sds-page) on vertical slab gel. silver staining of the gel after electrophoresis revealed 20 and 30 protein bands without and with reduction of immune complexes, respectively, in the molecular weight range of 148-18k. filarial antigen in protein eluates from gel slices was detected by sandwich enzyme-linked immunosorbent assa ... | 1988 | 3282713 |
filarial antigen in circulating immune complexes from patients with wuchereria bancrofti filariasis. | detection of filarial antigen in circulating immune complexes from patient sera was performed by an enzyme immunoassay in which the immune complexes were precipitated in the cold with polyethylene glycol and then dissociated in an acid ph buffer before being added to an elisa plate. the dissociated antigen bound to the plate where it could be detected by peroxidase-labeled polyclonal rabbit antifilarial antiserum. control sera used for defining the specificity of the assay included sera with imm ... | 1988 | 3281495 |
antibodies to diethylcarbamazine cross-react with microfilariae of wuchereria bancrofti. | antibodies directed against the microfilarial sheath have been instrumental in the immune elimination of circulating microfilariae in human lymphatic filariasis. we report here that antibodies to diethylcarbamazine (dec, the most commonly used anti-filarial drug) cross-react with the sheath of wuchereria bancrofti microfilariae. antibodies with reactivity to dec were raised in rabbits by immunization with a conjugate of methylpiperazine carboxylic acid (mpca, an acid hydrolysis product of dec) c ... | 1988 | 3280479 |
lymphatic filariasis: detection of circulating and urinary antigen and differences in antibody isotypes complexed with circulating antigen between symptomatic and asymptomatic subjects. | a two-site immunoradiometric assay using a monoclonal antibody (moab) against brugia malayi microfilariae allowed the detection of parasite molecules both in the serum and the urine of patients from sri lanka infected with wuchereria bancrofti. whereas 50% of patients had no antigen in their serum, all of them excreted detectable amounts of antigen in their urine, the levels being higher in symptomatic than in asymptomatic patients. the poor detection in serum appeared to be related to the prese ... | 1988 | 3280185 |
cytologic diagnosis of bancroftian filariasis in a nonendemic area. | parasitic infections are common in the developing countries, but the cytologic diagnosis of such infections is infrequent or rare. this paper presents four cases of filariasis caused by wuchereria bancrofti diagnosed by cytologic examination and discusses some unusual observations. the finding of microfilariae in pleural fluid in the absence of the classic symptoms and signs of tropical pulmonary eosinophilia is highlighted. in two patients, nocturnal microfilaremia could not be demonstrated des ... | 1988 | 3279714 |
bancroftian filariasis in haiti: preliminary characterization of the immunological responsiveness of microfilaremic individuals. | patent infections with the lymphatic filariae, wuchereria bancrofti and brugia malayi, are associated with suppressed in vitro cellular responsiveness to filarial antigens. in studies of bancroftian filariasis in haiti, a significant number of microfilaremic individuals can be characterized as "responders" to filarial antigens. cells from 37/74 untreated microfilaremic subjects responded to b. pahangi antigen (stimulation ratio greater than 2) as detected by in vitro blastogenesis. a comparison ... | 1988 | 3277457 |
an egg surface antigen of setaria digitata (filariae) shed on development to microfilariae. | egg surface antigens of setaria digitata were investigated by an immunoperoxidase staining technique. certain antigens on the egg surface were shed when the eggs developed to microfilariae. rabbit antisera to s. digitata eggs and to the soluble egg antigen reacted (as detected by immunoperoxidase staining) with the surface antigens of s. digitata eggs and immature microfilariae, and with mature microfilariae of wuchereria bancrofti and dirofilaria repens, but not with the surface antigens of mat ... | 1988 | 3256115 |
[advances in research on the immunopathogenic mechanism of lymphatic filariasis]. | 1986 | 3103893 | |
differentiation of three developmental stages of bancroftian and malayian filariae in mosquito vectors. | 1986 | 3100178 | |
two additional morphological characteristics for differentiating adult wuchereria bancrofti and brugia malayi. | 1986 | 3100162 | |
demonstration of species-specific and cross-reactive components of taenia solium metacestode antigens. | analysis of human serum reactivities to antigenic components of soluble taenia solium metacestode proteins showed the predominant presence of determinants shared by t. solium, echinococcus multilocularis and e. granulosus. two polypeptides were demonstrated by sds-page and western blot or enzyme-linked immunoelectrotransfer blot (eitb) assay to bind serum and csf antibodies only from t. solium cysticercosis patients. these species-specific antigenic polypeptides focused between ph 4.6 and 3.9 af ... | 1986 | 3082229 |
persistence of parasite antigenemia following diethylcarbamazine therapy of bancroftian filariasis. | this study was designed to reexamine the efficacy of diethylcarbamazine for bancroftian filariasis with special reference to changes in serum parasite antigen levels and antifilarial antibody titers after treatment. patients with asymptomatic microfilaremia were treated with 6 mg/kg diethylcarbamazine daily for 12 days. microfilaria counts fell dramatically after treatment, as expected. igg antibody titers to adult and microfilarial antigens of b. malayi were increased 1 month after treatment in ... | 1988 | 3079315 |
nodules in the conjunctiva, bung-eye, and bulge-eye in africa caused by mansonella perstans. | eight patients from uganda, sudan, nigeria, and zaire presented with swelling of the eyelids, proptosis, or conjunctival granulomas. in 5 patients the cause was mansonella perstans; in 1, it was a wuchereria bancrofti-like worm; and in 2, an unidentifiable worm. the morphologic features and histopathologic changes in the conjunctiva and periorbital fat are described and illustrated. | 1988 | 3079314 |
wuchereria bancrofti larvae in naturally infected culex quinquefasciatus. | 1988 | 3076752 | |
detection of infective larval antigens in bancroftian filariasis. | 1988 | 3076164 | |
[transectional surveillance in west hubei with filariasis basically eradicated]. | 1988 | 3075527 | |
[diagnosis of filariasis by indirect fluorescent antibody test with sonicated microfilariae malayi as antigen]. | 1988 | 3075522 | |
diethylcarbamazine prophylaxis against bancroftian filariasis given by a member of the local community in kenya. | 1988 | 3075443 | |
the effect of diethylcarbamazine treatment of bancroftian filariasis on the immunological reactivity of microfilaraemic individuals. | patent filarial infection has been correlated with a profound suppression of humoral and cellular responses to filarial antigens. in the present study, the filarial antigen-specific humoral and cellular reactivity of 30 haitian subjects with patent wuchereria bancrofti infection was monitored before and after treatment with diethylcarbamazine. microfilarial density was reduced from a pre-treatment mean of 1778/ml to 9/ml, with residual microfilaraemias detectable in 10 subjects. peripheral blood ... | 1988 | 3075359 |
epidemiology of wuchereria bancrofti in leogane, haiti. | a survey for wuchereria bancrofti in leogane, haiti, revealed that 140 of 421 individuals (33%) had a patent infection, of which 40% lived in the suburban outskirts of the city. the median microfilaria density was 19.1 per 20 mm3 of blood for suburban dwellers compared with only 8.8 for those living in the city. the vector, culex quinquefasciatus (say), breeds mostly in and around numerous rum distilleries, located exclusively around the periphery of the city, and this undoubtedly accounts for t ... | 1988 | 3075358 |
lymphatic filariasis: some recent trends and advances. | 1988 | 3073871 | |
[studies on the indirect fluorescent antibody test for diagnosis and surveillance of human filariasis]. | 1988 | 3072113 | |
use of mebendazole in combination with dec in bancroftian filariasis. | 1988 | 3071522 | |
[an unusual case of mediastinal lymphatic filariasis with pulmonary artery stenosis]. | 1988 | 3068713 | |
practical and effective dose schedule of diethylcarbamazine (dec) against bancroftian filariasis for mass therapy campaigns. | 1988 | 3068306 | |
comparative densities of wuchereria bancrofti microfilaria in paired samples of capillary and venous blood. | concurrent finger-prick and venous blood samples were obtained from 43 patients infected with wuchereria bancrofti. microfilariae were counted in blood smears and on nuclepore filters. based on the numbers of microfilariae in 20-microliters finger-prick samples, an expected (theoretical) number of microfilariae in venous samples was calculated. this expected value was compared to the actual number of microfilariae present in venous blood. the actual number of microfilariae present ranged from 0. ... | 1988 | 3067320 |
uptake and development of wuchereria bancrofti in aedes aegypti and haitian culex quinquefasciatus that were fed on a monkey with low-density microfilaremia. | colonized mosquitoes of culex quinquefasciatus (haitian strain) and aedes aegypti (liverpool strain) were blood fed on a patas monkey (erythrocebus patas) that had been experimentally infected with the haitian strain of wuchereria bancrofti and harbored a consistently low microfilaremia (1-3 mf per 20 mm3). both species ingested more than twice the expected number of microfilariae (mf), i.e. 1.9 and 0.77 mf per mosquito, respectively. however, at 10-16 hours post ingestion only 4.2% of the mf ha ... | 1988 | 3057592 |
circulating antibodies and antigens in presbytis monkeys infected with the filarial parasite wuchereria bancrofti. | levels of circulating filarial antigen, and humoral antibody to other defined antigenic targets, were measured over the course of experimental infection of three presbytis cristatus monkeys with wuchereria bancrofti. circulating antigen levels, measured with an anti-phosphorylcholine monoclonal antibody, varied widely although all animals were positive for some period of the infection. circulating antigen levels tended to be inversely related to the titre of anti-phosphorylcholine antibody, and ... | 1988 | 3057591 |
[study on the role of low density microfilaremia cases in the transmission of filariasis in late stage of filariasis control]. | 1988 | 3052910 | |
factors affecting transmission of wuchereria bancrofti by anopheline mosquitoes. 2. damage to ingested microfilariae by mosquito foregut armatures and development of filarial larvae in mosquitoes. | microfilariae (mf) of wuchereria bancrofti from the midgut of 639 anopheles gambiae, 557 an. arabiensis, 117 an. melas and 9 an. funestus were examined immediately after the mosquitoes had fed on carriers with different densities of mf. the percentages of mf damaged during ingestion were 57.1-60.0 in an. gambiae, 33.3-50.6 in an. arabiensis and 38.7-55.7 in an. melas. in each species the percentage of mf damaged was independent of mf density in the human host. a further 3657 an. gambiae, 2875 an ... | 1988 | 3051543 |
factors affecting transmission of wuchereria bancrofti by anopheline mosquitoes. 1. uptake of microfilariae. | ingestion of wuchereria bancrofti microfilariae (mf) from humans by 639 anopheles gambiae, 557 an. arabiensis, 117 an. melas and 9 an. funestus was investigated. the mf densities in blood fell into 3 groups; 0-32mf/ml, 107-122 mf/ml and 421-1140 mf/ml. in an. gambiae and an. arabiensis percentage of mosquitoes ingesting mf was strongly associated with mf density in host blood; in an. melas the association was much weaker. mean number of mf ingested per mosquito was also strongly correlated to mf ... | 1988 | 3051542 |
a quantitative analysis of the diagnostic value of diethylcarbamazine provocation in endemic wuchereria bancrofti infection. | the efficiency (delta) of the day-time provocative effect of diethylcarbamazine (dec) on the circulation of microfilariae (mf) of nocturnally periodic wuchereria bancrofti compared with the night mf count was evaluated in terms of sensitivity and specificity. in one test, the mean mf count for finger-blood samples from the same person on 3 successive nights was compared with the day-time post-dec count; another test compared the mf count in one night-time finger-blood sample with the following d ... | 1988 | 3051541 |
persistence of microfilaremia in bancroftian filariasis after diethylcarbamazine citrate therapy. | of 58 patients in leogane, haiti, infected with wuchereria bancrofti and treated with diethylcarbamazine citrate (dec-c) at 6 mg/kg per day for 12 days (= 72 mg/kg), 38 (66%) of 58 continued to harbor low numbers of circulating microfilariae (median microfilariae could be demonstrated in 7 (37%) of 19 patients, with a median microfilarial density of 8 mf/ml. three patients who continued to have circulating microfilariae after two courses of dec-c were treated a third time. two (67%) of the three ... | 1988 | 3051291 |
evaluation of integrated vector control measures on filariasis transmission in pondicherry. | 1988 | 3049328 | |
bancroftian filariasis in the igwun basin, nigeria: an epidemiological, parasitological, and clinical study in relation to the transmission dynamics. | a 12-months study on bancroftian filariasis was carried out in the igwun basin, nigeria. a total of 1,418 individuals (768 males, and 650 females) were examined for microfilaremia and clinical filarial stigmata. there were 14.3% and 11.1% male and female point prevalence rates, respectively, and an overall prevalence of 12.8%. prevalence rates and microfilarial density increased with age. the highest mff density of 35 mff/20 ml blood occurred in the 40-49 year old male individuals. disease rates ... | 1988 | 3049274 |
diagnosis of bancroftian filariasis by detection of circulating antigens by counterimmunoelectrophoresis. | 1988 | 3047273 | |
filariasis in the igwun river basin, nigeria: an epidemiological and clinical study with a note on the vectors. | in a cross-sectional, epidemiological and parasitological study of human filariasis, 845 individuals were examined in settlements along the igwun basin, imo state, nigeria. four different filarial nematode species were identified. two hundred and fifty-six (30.3%) of the individuals examined were positive for onchocerca volvulus, 113 (13.4%) for mansonella perstans, 76 (9.6%) for wuchereria bancrofti and 77 (9.1%) for loa loa. microfilarial rates increased with age of individuals and showed a te ... | 1988 | 3041931 |
a study of arthritis in papua new guinea. | a study was undertaken of 182 melanesian patients with arthritis who were admitted to three major hospitals in papua new guinea between 1977 and 1982. there were 118 male and 64 female subjects, whose mean ages were 29 years and 25 years respectively. a diagnosis was made in 101 cases (55.5%) but in 81 cases, because assessment and management had been inadequate, a diagnosis could not be made. the commonest cause was infectious arthritis (44%), followed by rheumatoid arthritis (14%), gout (8%), ... | 1987 | 3039954 |
defective concanavalin a-induced suppression in bancroftian filariasis. | a concanavalin-a-induced suppressor cell assay was carried out in 10 patients with chronic filarial disease, 13 asymptomatic microfilaria carriers and 7 healthy subjects. both the chronic filarial patients and the asymptomatic microfilaria carriers showed statistically significant reduced suppression indices when compared with the control subjects. the reduction in suppression indices was greater in the microfilaria carriers than in the chronic filarial patients. | 1987 | 2956197 |
reduced lymphocyte response to mitogens in patients with bancroftian filariasis. | peripheral blood lymphocytes from patients with acute and chronic wuchereria bancrofti infections responded poorly to concanavalin a, phytohaemagglutinin and pokeweed mitogen when cultured in heat-inactivated pooled normal serum. the lymphocyte response to mitogens in carriers of microfilariae (mff) were normal. the suppression of transformation to mitogens was not reversible by the removal of plastic adherent cells. incubation with mitogens and the adult filarial worm antigen (bma) did not alte ... | 1986 | 2941905 |
filariasis programme--recife--brazil. | 1987 | 2908187 | |
quantitation of antibodies to infective larvae in wuchereria bancrofti filariasis. short communications. | 1988 | 2907266 | |
a study of bancroftian filariasis on the islands of batan and rapu rapu, philippines. | the islands of batan and rapu rapu in southeastern luzon, philippines, were surveyed for filariasis from november 1984 to may 1985. microfilariae of bancroftian filariasis were detected in 10.5% of the people over one year of age. microfilarial rates and intensity of infection were the same for males and females. the highest rates for both sexes were in the 56- to 60-year-old age group. aedes poicilius, which breeds in abaca and banana plants, was found to be very anthropophilic, comprising 96.5 ... | 1988 | 2906482 |
microfilaraemia, filarial antibody, antigen and immune complex levels in human filariasis before, during and after dec therapy. a two-year follow-up. | a study on the effect of dec therapy on microfilaraemia and the immune status in 27 patients with w. bancrofti infection was carried out for two years. persistence of microfilaraemia was observed in 4 out of 27 cases after one course of dec therapy and were treated again for one week. on further follow-up, none was microfilaraemic upto day 60. the mean filarial antibody titres of igm and igg showed a gradual decrease as assessed by enzyme linked immunosorbent assay (elisa). the mean titres of ci ... | 1988 | 2903626 |
investigations of filarial worms of man in metropolitan lagos. short communication. | 1988 | 2901210 | |
bancroftian filariasis in the igwun basin, nigeria. an epidemiological, parasitological, and clinical study in relation to the transmission dynamics. | a 12-month field and laboratory study was carried out to determine the epidemiology, clinical features, and transmission dynamics of bancroftian filariasis in the igwun basin, nigeria. a total of 1,418 individuals (768 males, and 650 females) were examined for clinical signs of filariasis. 690 day provocative blood samples (dps), and 728 night blood samples (nbs) were examined for microfilaremia. 14.3% of males and 11.1% of females were mf positive. 5.8% of dps, and 19.5% of the nbs were mf posi ... | 1988 | 2901204 |
application of biotechnology in the identification of filarial larva in mosquitoes. | current methods for detecting and identifying filariae in mosquitoes are laborious and time consuming. with today's technology, we can reasonably expect development of rapid, sensitive and specific assays for detecting and identifying filariae in naturally infected mosquito populations. progress in developing such assays is reviewed. | 1988 | 2900557 |
[lymphatic filariasis in vanuatu]. | lymphatic filariasis, in the archipelago of vanuatu, is due to wuchereria bancrofti. the vector is anopheles farauti, endophilic mosquito, which transmits also malaria. the level of endemicity was very high in the beginning of this century (microfilariae in blood: 60.9%, elephantiasis: 21%), and has dramatically decline now by detection and treatment of sick people (70 cases in 1986), mass chimioprophylaxis and protection against the vectors. but these actions must be continued to obtain the era ... | 1987 | 2894256 |
epidemiology of lymphatic filariasis. | human lymphatic filariasis is caused mainly by wuchereria bancrofti, brugia malayi and brugia timori. of the estimated 90.2 million people infected, more than 90% have bancroftian and less than 10% brugian filariasis. the distribution and transmission of the disease are closely associated with socioeconomic and behavioural factors in endemic populations. urban w. bancrofti infection, as seen in south-east asia, is related to poor urban sanitation, which leads to intense breeding of culex quiquef ... | 1987 | 2885159 |
lectin-binding characteristics of wuchereria bancrofti microfilariae. | the binding of 10 different lectins to the surface of microfilariae of wuchereria bancrofti has been investigated. wheat germ agglutinin (wga) and helix pomatia lectin (hpa) bound specifically to the sheathed microfilariae indicating the presence of n-acetyl-d-glucosamine and n-acetyl-d-galactosamine respectively on the surface. exsheathed microfilariae did not react with any of the lectins. treatment of sheathed microfilariae with proteases resulted in increased binding of wga and hpa. such tre ... | 1987 | 2884837 |