Publications

structure of the tubular variants of the head of bacteriophage t4 (polyheads). i. arrangement of subunits in some classes of polyheads.		1972	5023668
synergistic inactivation of viruses by heat and ionizing radiation.	viral inactivation by heat and/or ionizing radiation is analyzed in terms of a kinetic model. the phenomenon of synergistic viral inactivation observed when viruses are exposed to the simultaneous application of heat and ionizing radiation is interpreted within the framework provided by this three-term model. data on the inactivation of t4 bacteriophage by heat and/or ionizing radiation is presented, and the kinetic model is used to provide a description of observed dose rate and temperature dep ...	1972	5007243
the effect of phage t4 infection on phospholipid hydrolysis in escherichia coli.		1971	4999127
t4-coliphage infection of escherichia coli with defective cell envelopes.		1971	4998188
[mechanism of replication of t4 bacteriophage].		1971	4997903
sedimentation of dna released from chinese hamster cells.	under high ph and high salt conditions, chinese hamster cells lyse and release a dna-containing material of large molecular weight. with increasing lysis time, a smaller material is resolved from the large one. relative to t4 dna, the smaller is estimated to be approximately 2 x 10(8) daltons (number average). from a comparison of radiation data, the target size of the larger is about 15 times that of the smaller (probably a lower limit estimate). in addition to concentration of alkali, temperat ...	1971	4997648
transfection of escherichia coli spheroplasts. i. general facilitation of double-stranded deoxyribonucleic acid infectivity by protamine sulfate.	the addition of 25 mug of protamine sulfate per ml to lysozyme-ethylenediamine-tetraacetic acid spheroplasts of escherichia coli stimulates transfection not only for t1 phage deoxyribonucleic acid (dna; hotz and mauser, 1969) but also for the following phage dna species: lambda, 10,000-fold to an efficiency of 10(-3) infective centers per dna molecule; phix174 replicative form, 300-fold to an efficiency of 5 x 10(-2); fd replicative form, 300-fold to 10(-6); t7, 300-fold to 3 x 10(-7). three nat ...	1971	4997550
[the suppressor functions of "r" genes of t4 d bacteriophage].		1971	4995033
some factors affecting the viability of freeze-thawed t4 bacteriophage.		1969	4993555
observations on the maturation of thyroid function in early fetal life.	serum samples were obtained from 21 normal human fetuses after therapeutic abortion for psychiatric indications. fetal crown-rump length ranged from 5.2 to 22.5 cm, corresponding to the gestational age of 65-168 days.serum thyroxine, assayed by a modification of the murphy-pattee method, was identified in the second smallest fetus examined at 78 days gestation. thereafter it increased rapidly, maintaining a significant linear correlation with crown-rump length until term (r = 0.800, p < 0.001). ...	1970	4989616
mechanism of dna chain growth. iv. direction of synthesis of t4 short dna chains as revealed by exonucleolytic degradation.	t4 nascent short chains labeled at their growing ends with h(3)-thymidine and uniformly with c(14)-thymidine were prepared, separated into complementary strands, and degraded by e. coli exonuclease i in the 3' to 5' direction or by b. subtilis nuclease in the 5' to 3' direction. the kinetics of release of h(3) and c(14) labels by both enzymes was consistent with the conclusion that the h(3) label is at the 3' end of the nascent short chains of both strands and that the short chains are products ...	1969	4989398
early intracellular events in the replication of t4 bacteriophage deoxyribonucleic acid. vii. 32p suicide stabilization.	the relationship between (32)p suicide stabilization and deoxyribonucleic acid (dna) replication during infection of escherichia coli by bacteriophage t4 was reinvestigated. replication of the parental phage dna was detected at early stages of stabilization.	1970	4989103
familial thyroxine-binding globulin deficiency.	genetically determined thyroxine-binding globulin deficiency is described in two families in the united kingdom. all subjects in both pedigrees were euthyroid. transmission was by sex-linkage; males showed low serum protein bound iodine and high thyroxine (t4) resin uptake due to complete absence of serum thryroxine-binding globulin; females were less severely affected. the distinctive biochemical results disclosed the diagnosis and emphasize that serum protein bound iodine levels should be inte ...	1970	4987801
conversion of thyroxine (t4) to triiodothyronine (t3) in athyreotic human subjects.	studies of the possibility that thyroxine (t4) is converted to 3.5,3'-triiodo-l-thyronine (t3) in the extrathyroidal tissues in man have been conducted in 13 patients, all but two of whom were athyreotic or hypothyroid, and all of whom were receiving at least physiological replacement doses of synthetic sodium-l-thyroxine.t3 was found in the sera of all patients, in concentrations ranging between 243 and 680 ng/100 ml (normal range 170-270 ng/100 ml). these concentrations were far in excess of t ...	1970	4986007
template properties of complementary fractions of denatured microbial deoxyribonucleic acids.	dna preparations from seven bacterial species and from e. coli phage t4, and also the complementary l and h fractions into which these dna specimens, after denaturation, were separated by chromatography on methylated albumin-kieselguhr columns, were studied as templates in the rna polymerase system, and the nucleotide composition of the rna products was determined. the rna transcripts of the separated l and h fractions were found to be faithful copies of the respective dna fractions. this sugges ...	1970	4985881
resistance of escherichia coli to penicillins. 8. physiology of a class ii ampicillin-resistant mutant.	class ii ampicillin-resistant mutants of escherichia coli are defined as having a twofold increase in penicillinase-mediated ampicillin resistance when determined by colony formation tests on plates. in this paper, one class ii mutant has been compared to its parent strain. in liquid medium, the mutant was less resistant than the parent strain both in the absence and in the presence of r1 and r-factor mediating penicillinase activity. the penicillinase activity was found to be almost completely ...	1970	4985589
separation of thyroxine(t4)-binding proteins of human serum in polyacrylamide gel at ph 7.4. i. effect of ph on distrubution of tracer quantities of t4.		1970	4984013
[the radiological treatment of deeply infiltrating bladder cancer (t3-t4)].		1969	4982980
separation of microbial deoxyribonucleic acids into complementary strands.	dna preparations from seven bacterial species and from the e. coli phage t4 can, after denaturation with alkali, be separated chromatographically into two distinct components (l and h) through intermittent gradient elution from methylated albumin kieselguhr columns. the direct chemical analysis of the l and h fractions isolated from dna specimens of the at type shows them to exhibit a high degree of complementarity; but despite a bias in the distribution of purines and pyrimidines, either fracti ...	1969	4980029
[attachment of lambda and t4 phage deoxyribonucleic acids to an escherichia coli membrane particle fraction and functions of the complex in transcription of dna to specific messenger rna].		1969	4979265
effect of epinephrine on the peripheral metabolism of thyroxine.	10 normal young men received repository epinephrine repeatedly for 4 days during the course of a radiothyroxine (radio-t4) disappearance curve. during epinephrine administration, serum radio-t4 disappearance rate (k) slowed abruptly, fecal clearance decreased, urinary clearance was initially unchanged but later decreased slightly, volume of thyroxine distribution decreased, and external radioactivity over the liver remained unchanged. beginning on day 2 of epinephrine and persisting at least 1 d ...	1969	4977031
conservation of the rifamycin sensitivity of transcription during t4 development.		1969	4974639
evidence for a magnesium pump induced by bacteriophage t4.		1968	4972798
the instability of t4 messenger rna.		1967	4964032
folic acid, a structural component of t4 bacteriophage.		1965	4955313
localization of parental deoxyribonucleic acid from superinfecting t4 bacteriophage in escherichia coli.	high-resolution autoradiography has been employed to localize the nonsolubilized but genetically excluded deoxyribonucleic acid (dna) of t4 bacteriophage superinfecting endonuclease i-deficient escherichia coli. this dna was found to be associated with the cell envelope (this term is used here to include all cellular components peripheral to and including the cytoplasmic membrane); in contrast, t4 dna in primary infected cells, like host dna in uninfected e. coli, was found to be near the cell c ...	1971	4950703
polyamines and the delay in deoxyribonucleic acid synthesis in some bacteriophage t4 infections.	escherichia coli b infected by the dd mutant of t4, am n116, is stimulated to initiate deoxyribonucleic acid accumulation by 1 to 10 mm spermidine but not by 10 mm putrescine. the syntheses of putrescine and spermidine in cells infected by t4d and the mutant are similar, although slight differences are observed in the intracellular concentration of free spermidine. unlike r-k12 (lambda) systems, am n116-infected cells do not leak polyamine.	1971	4950691
breakdown and exclusion of superinfecting t-even bacteriophage in escherichia coli.	in bacterial strains containing the deoxyribonuclease endonuclease i (endonuclease i(+) strains), 70 to 80% of the injected superinfecting t-even phage deoxyribonucleic acid (dna) is rapidly degraded to oligonucleotides having an average chain length of 8, the same value as that obtained by endonuclease i digestion of purified t-even phage dna in vitro. in endonuclease i(-) strains, less than 5% of the injected superinfecting t-even phage dna is degraded to acid-soluble components. the superinfe ...	1971	4950690
superinfection with bacteriophage t4: inverse relationship between genetic exclusion and membrane association of deoxyribonucleic acid of secondary bacteriophage.	the majority of the deoxyribonucleic acid (dna) of superinfecting t4 bacteriophage which is injected and not hydrolyzed does not attach to host cell membrane. low levels of association of secondary phage dna with membrane appear to be related to temporal genetic exclusion.	1971	4950688
genetic transformation of the phage t4riib by dna of the phage t4r+. 13. minimal length of dna parts required for integration of the donor fragments in phage t4 transformation.		1971	4950360
interruption of the phage t4 chromosome transfer into the cell. cyclic permutations of genes, and infective activity of the fragmented genome.		1971	4949478
dna replication and phage t4 formation in infected cells of escherichia coli with preaccumulated phage dna.		1971	4949470
a reduced activity of a deoxyribonuclease requiring atp in escherichia coli infected by bacteriophage t4.		1971	4946708
stimulation of t4 bacteriophage dna polymerase by the protein product of t4 gene 32.		1971	4945535
dna synthesis in bacteriophage t4-infected escherichia coli: evidence supporting a stoichiometric role for gene 32-product.		1971	4945534
properties and mode of action of a bactericidal compound (=methylglyoxal) produced by a mutant of escherichia coli.	a lethal product (bpg) produced by a glycerol kinase mutant of escherichia coli was purified, and its mode of action on e. coli was studied. at concentrations where bpg strongly inhibits in vivo deoxyribonucleic acid, ribonucleic acid, and protein synthesis, it produces small effects on other functions: slight inhibition of respiration and small changes in intracellular pools of substrates, nucleic acids degradation, and adenosine triphosphate levels. bpg also inhibits in vitro protein synthesis ...	1971	4945198
resistance of escherichia coli to penicillins. ix. genetics and physiology of class ii ampicillin-resistant mutants that are galactose negative or sensitive to bacteriophage c21, or both.	ampicillin-resistant mutants of class ii are determined by a doubling of chromosomally and episomally mediated ampicillin resistance on agar plates. several mutants were isolated from a female as well as from an hfr strain. the mutants differed from each other in various properties such as response to colicin e2 and sodium cholate, response to the phages t4 and c21, and fermentation of galactose. by conjugation and transduction experiments, it was shown that mutations in at least four loci gave ...	1971	4945191
role of initiation factors in the control of t4-specific protein synthesis.		1971	4944933
phospholipid hydrolysis before the onset of lysis in t4-infected escherichia coli.		1971	4944865
properties of the dna-delay mutants of bacteriophage t4.		1971	4944864
regulation of rii and region d transcription in t4 bacteriophage: a sucrose gradient analysis.		1971	4944863
structure of the dna ligase-adenylate intermediate: lysine (epsilon-amino)-linked adenosine monophosphoramidate.	proteolytic degradation of the escherichia coli dna ligase-adenylate intermediate releases adenosine 5'-monophosphate linked to the epsilon-amino group of lysine by a phosphoamide bond. measurements of the rate of hydroxylaminolysis of the ligase-adenylate provide further support for a phosphoamide linkage in the native enzyme. lysine (epsilon-amino)-linked adenosine monophosphoramidate has also been isolated from the t4 phage-induced ligase-adenylate intermediate. these results indicate that an ...	1971	4944632
assembly of bacteriophage t4 tail fibers. 3. genetic control of the major tail fiber polypeptides.		1971	4944598
the role of gene 49 in dna replication and head morphogenesis in bacteriophage t4.		1971	4944597
infectious dna of bacteriophage t4.		1971	4944596
inhibition of host deoxyribonucleic acid synthesis by t4 bacteriophage in the absence of protein synthesis.	the requirement for phage protein synthesis for the inhibition of host deoxyribonucleic acid synthesis has been investigated by using a phage mutant unable to catalyze the production of any phage deoxyribonucleic acid. it has been concluded that the major pathway whereby phage inhibit host syntheses requires protein synthesis. the inhibition of host syntheses by phage ghosts is not affected by inhibitors of protein synthesis.	1971	4943684
control of gene function in bacteriophage tr. 3. preventing the shutoff of early enzyme synthesis.	synthesis of early t4 protein, which is normally shut off at 10 min after infection, continues until lysis when host cells have been preinfected with t3 sam(+). in host cells preinfected with t3 sam(-), synthesis of early enzymes is shut off as normal. thus, s-adenosylmethionine is required for the turnoff of early t4 functions (at least when host cells have been preinfected with t3).	1971	4943682
specific suppression of mutations in genes 46 and 47 by das, a new class of mutations in bacteriophage t4d.	mutants in t4 genes 46 and 47 exhibit early cessation of deoxyribonucleic acid (dna) synthesis ("dna arrest") and decreased synthesis of late proteins and phage. in addition, mutants in genes 46 and 47 fail to degrade host dna to acidsoluble products. it is shown here that this complex phenotype can be partially suppressed by mutation of a t4 gene external to genes 46 and 47 which has been named das for "dna arrest suppressor." the das mutations were discovered as third-site mutations in spontan ...	1971	4943681
structure of the replicating dna from bacteriophage t4.	at an early stage of replication, parental t4 dna shows a loop structure often displaying two 3'-ended, single-stranded "whiskers", located in trans configuration at the branching-points. several such loops have been observed within a single t4 molecule. occasionally, reinitiation occurred in the middle of a loop, which suggests that the loop was growing in both directions.	1971	4943552
t4 dna replication and viral gene expression.		1971	4943226
host dna synthesis after infection of escherichia coli with mutants of bacteriophage t4.		1971	4943194
infectious dna preparations from t2 and t4 bacteriophages.		1971	4943190
the selective inhibition of protein initiation by t4 phage-induced factors.	the phenomenon of selective translation of t4 template rna by ribosomes from t4-infected cells, or factors derived therefrom, has been extended to studies on the initiation of protein synthesis. a high-salt extract derived from t4-infected ribosomes inhibits the formation of initiation complexes of ms2 and escherichia coli template rna with uninfected ribosomes while efficiently supporting the formation of initiation complexes with t4 template rna. t4 factors also permit t5 template rna to bind ...	1970	4943180
inhibition of replication of ribonucleic acid bacteriophage f2 by superinfection with bacteriophage t4.	superinfection by phage t4 of cells infected by the ribonucleic acid (rna) phage f2 results in inhibition of further f2 production. experiments using rifampin show that the exclusion of f2 requires t4 gene function soon after t4 infection. by using a sensitive new peptide-mapping procedure to identify f2 coat protein in infected cells, we show that synthesis of the f2 coat occurs at a reduced level until 4 min after t4 superinfection and then ceases abruptly. within 4 min after t4 superinfection ...	1971	4943076
role of genes 46 and 47 in bacteriophage t4 reproduction. i. in vivo deoxyribonucleic acid replication.	functional proteins coded by genes 46 and 47 are required for (i) continuation of deoxyribonucleic acid (dna) synthesis in the late period of t4 infection and (ii) production of normal, late replicating dna which contains strands with a sedimentation coefficient in alkaline sucrose greater than that of mature dna (73s). continued dna synthesis in the late period in the absence of functional genes 46 or 47 can be achieved by inhibiting late protein synthesis either by using bacterio-phage with a ...	1971	4943075
in vitro synthesis of deoxynucleotide kinase programmed by bacteriophage "t4-rna.	rna extracted from t4 phage-infected escherichia coli cells can direct the synthesis of phage-specific deoxynucleotide kinase in a cell-free system from uninfected e. coli. the maximum messenger activity is obtained 8 min after infection at 37 degrees c and decreases there-after. the main activity of this messenger rna has a sedimentation coefficient of about 15 s on a sucrose density gradient. the conditions necessary for the appearance of enzyme activity in vitro are the same as those required ...	1971	4942183
bacteriophage t4 inhibits colicin e2-induced degradation of escherichia coli deoxyribonucleic acid. i. protein synthesis-dependent inhibition.	the deoxyribonucleic acid (dna) of escherichia coli b is converted by colicin e2 to products soluble in cold trichloroacetic acid; we show that this dna degradation (hereafter termed solubilization) is subject to inhibition by infection with bacteriophage t4. at least two modes of inhibition may be differentiated on the basis of their sensitivity to chloramphenicol. the following observations on the inhibition of e2 by phage t4 in the absence of chloramphenicol are described: (i) simultaneous ad ...	1971	4940930
biochemistry of dna-defective amber mutants of bacteriophage t4. ii. intracellular dna forms in infection by gene 44 mutants.		1969	4940919
addition of nucleotides to parental dna early in infection by bacteriophage t4.		1969	4940918
suppression of temperature sensitive mutants of bacteriophage t4 by bacterial opal suppressors.		1971	4940425
role of gene 46 in bacteriophage t4 deoxyribonucleic acid synthesis.	in an attempt to establish whether escherichia coli b infected with n130 (an amber mutant defective in gene 46) is recombination-deficient, the postinfection fate of (14)c-labeled n130 parental deoxyribonucleic acid (dna) was followed, its amount in complex with the host cell membrane being determined in sucrose gradients after mild lysis of the infected cells. the parental dna was found to undergo gradual detachment from the membrane during infection. pulse-chase experiments similarly showed th ...	1971	4940242
an in vitro transversion by a mutationally altered t4-induced dna polymerase.		1968	4939629
partial suppression of bacteriophage t4 ligase mutations by t4 endonuclease ii deficiency: role of host ligase.	endonuclease ii-deficient, ligase-deficient double mutants of phage t4 induce considerably more deoxyribonucleic acid (dna) synthesis after infection of escherichia coli b than does the ligase-deficient single mutant. furthermore, the double mutant can replicate 10 to 15% as well as wild-type t4, whereas the single mutant fails to replicate. when the e. coli host is also deficient in ligase, the double mutant resembles the single mutant. the results indicate that host ligase can substitute for p ...	1971	4939389
identity of genes coding for soluble and structural dihydrofolate reductases in bacteriophage t4.	by recombination between bacteriophage t4 wh2, a dihydrofolate reductaseless mutant, and t6, i have prepared t4 wh(t6), a t4 strain which codes for the t6-specific soluble dihydrofolate reductase. this strain has the heat sensitivity of t6, not t4, which provides direct evidence that the wh gene codes for both the soluble dihydrofolate reductase and the structural dihydrofolate reductase which is a constituent of t-even phage tail plates.	1971	4939388
reversion of frameshift mutations stimulated by lesions in early function genes of bacteriophage t4.	temperature-sensitive (ts) mutants representative of a number of genes of phage t4 were crossed with rii mutants to allow isolation of ts, rii double-mutant recombinants. the rii mutations used were characterized as frameshift mutations primarily on the basis of their revertability by proflavine. for each ts, rii double mutant, the effect of the ts mutation on spontaneous reversion of the rii mutation was determined over a range of incubation temperatures. a strong enhancement in reversion of tw ...	1971	4939385
a suppressor in the genome of phage t4 inhibiting phenotypic expression of mutations in genes 46 and 47.		1971	4939139
properties of bacteriophage t4 mutants defective in gene 30 (deoxyribonucleic acid ligase) and the rii gene.	in escherichia coli k-12 strains infected with phage t4 which is defective in gene 30 [deoxyribonucleic acid (dna) ligase] and in the rii gene (product unknown), near normal levels of dna and viable phage were produced. growth of such t4 ligase-rii double mutants was less efficient in e. coli b strains which show the "rapidlysis" phenotype of rii mutations. in pulse-chase experiments coupled with temperature shifts and with inhibition of dna synthesis, it was observed that dna synthesized by gen ...	1971	4939059
complete primary structure of phage lysozyme from escherichia coli t4.		1968	4939036
origin and direction of bacteriophage t4 dna replication. ii. a gradient of marker frequencies in partially replicated t4 dna as assayed by transformation.		1971	4938732
identification of the transcribing dna strand for the rii and endolysin genes of coliphage t4.		1968	4938565
chain growth rate of messenger rna in escherichia coli infected with bacteriophage t4.		1968	4938556
genetic distances separating adjacent base pairs in bacteriophage t4.		1971	4937995
nuclease activity in a fragment of bacteriophage t4 deoxyribonucleic acid polymerase induced by the amber mutant am b22.		1971	4937662
in vitro transcription of t4 deoxyribonucleic acid by escherichia coli ribonucleic acid polymerase. sequential transcription of immediate early and delayed early cistrons in the absence of the release factor, rho.		1971	4937660
physiological studies on the t gene defect in t4-infected escherichia coli.		1971	4937243
specific cleavage of an escherichia coli leucine transfer rna following bacteriophage t4 infection.		1971	4937193
branched dna molecules: intermediates in t4 recombination.		1971	4937189
enzymatic breakage and joining of deoxyribonucleic acid. ix. synthesis and properties of the deoxyribonucleic acid adenylate in the phage t4 ligase reaction.		1971	4937131
virus-genetic theory testing by data processing machines. 3. the intepretation of radiation genetic and partial phage experiments in t4. general remarks on the theory-testing rsults.		1971	4936897
virus-genetic theory testing by data processing machines. ii. fit of classical genetic t4 data.		1971	4936896
canavanine-induced fast-sedimenting complexes with escherichia coli dna and bacteriophage t4 dna.		1971	4936515
transcription of rna polymerase binding sites isolated from t4 phage dna.		1971	4936433
recombination in bacteriophage t4.		1970	4936424
repair of uv-induced mutations in phage t4.		1971	4936341
t4 bacteriophage-specific dihydrofolate reductase: purification to homogeneity by affinity chromatography.		1971	4936128
orientation of tail fibers in t4 z mutants and the influence of r mutations.		1971	4935678
metabolism of t4 bacteriophage ghost-infected cells: effect of bacteriophage and ghosts on the uptake of carbohydrates in escherichia coli b.	ghosts of t4 bacteriophage inhibit the uptake of thiomethyl-beta-galactoside (tmg), alpha-methylglucoside, glucose-6-phosphate, and glycerol in escherichia coli b. the transport of orthonitrophenyl-beta-galactoside (onpg) is also inhibited to a lesser degree and without alteration of the apparent k(m) of transport. these effects of ghosts parallel those of energy poisons on these systems. however, no one energy poison can produce such pronounced inhibitory effects in all these systems. the effec ...	1971	4935322
synthesis of ribonucleic acid and protein in plasmid-containing minicells of escherichia coli k-12.	unlike the deoxyribonucleic acid (dna)-deficient minicells produced by f(-) parents, minicells produced by plasmid-containing strains contain significant amounts of plasmid dna. we examined the ability of plasmid-containing minicells to synthesize ribonucleic acid (rna) and protein. in vivo, minicells produced by f(-) parents are unable to incorporate radioactive precursors into acid-insoluble rna or protein, whereas minicells produced by f', r(+), or col(+) parents are capable of such synthesis ...	1971	4935321
5-fluorouracil rescue of dcmp hydroxymethylase in escherichia coli b infected by mutant am n122 of bacteriophage t4.		1970	4934310
partial exclusion of genes of bacteriophage t2 with t4-glucosylated dna in crosses with bacteriophage t4.		1970	4934195
role of pyridine nucleotides in 5-fluorouracil-mediated reactivation of ultraviolet radiation damage.	ultraviolet irradiation (520 ergs/mm(2) at 254 nm) causes the respiration of escherichia coli b/r cells to cease after about 90 min postirradiation incubation in a minimal medium containing glycerol as the sole source of carbon. the cessation of respiration is associated with loss of pyridine nucleotides. agents which interfere with postirradiation transcription and translation prevent cessation of respiration. we have studied the effects of one of these agents, 5-fluorouracil (fu), on respirati ...	1971	4934068
the identification of complex genotypes in bacteriophage t4. i. methods.		1970	4933468
cryptic mutants of bacteriophage t4.		1970	4933467
bacteriophage t4 tail assembly: four steps in core formation.		1971	4933424
the sequence of gene product interaction in bacteriophage t4 tail core assembly.		1971	4933423
an isotopic study of dna-dependent rna polymerase of e. coli following t4 phage infection.		1970	4931930
enzymatic properties of bacteriophage t4 altered and modified rna polymerase as compared to dna-dependent rna polymerase from e. coli (ec 2.7.7.6).		1971	4931577
mutants of bacteriophage t4 defective in the induction of t4 endonuclease ii.		1971	4930062
dark repair of ultraviolet-irradiated deoxyribonucleic acid by bacteriophage t4: purification and characterization of a dimer-specific phage-induced endonuclease.	the purification and properties of an ultraviolet (uv) repair endonuclease are described. the enzyme is induced by infection of cells of escherichia coli with phage t4 and is missing from extracts of cells infected with the uv-sensitive and excision-defective mutant t4v(1). the enzyme attacks uv-irradiated deoxyribonucleic acid (dna) containing either hydroxymethylcytosine or cytosine, but does not affect native dna. the specific substrate in uv-irradiated dna appears to be pyrimidine dimer site ...	1971	4929862
the effect of bacteriophage t4 infection on an atp-dependent deoxyribonuclease in escherichia coli.		1971	4929432