Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| transfer of ultraviolet light induced thymine dimer from parental to progeny dna in bacteriophage t1 and t4. | 1968 | 5696504 | |
| frame shift mutations near the beginning of the lysozyme gene of bacteriophage t4. | a pair of frame shift mutations in the lysozyme gene of bacteriophage t4 results in the substitution of a glutamyl-tyrosyl sequence for the asparagine residue that is the penultimate amino-terminal amino acid in the lysozyme of the wild-type strain. one of the mutations has been identified as the insertion of two bases, the other as the insertion of a single base. | 1968 | 5686221 |
| the effect of ultraviolet light on the intracellular stability of the dna of bacteriophages t2 and t4. | 1968 | 5683009 | |
| induction of mutation in phage t4 by extracellular treatment with methylene blue and visible light. | 1968 | 5683001 | |
| the mechanism of inactivation of t4 bacteriophage by tritium decay. | coliphage t4 was used as a model system to study the mechanism of biological inactivation produced by tritium decay. experimentally, tritiated precursors were incorporated into phage dna (thymidine-(3)h) or into phage protein ((3)h-amino acids). the ratio of killing efficiencies for decays originating in phage dna to those originating in phage protein was 2.6. inactivation by decays from labeled amino acids was assumed to occur exclusively from beta-particle irradiation of phage dna. if decays o ... | 1968 | 5678320 |
| the mutagenic effect of hydroxyaminopurine derivatives on phage t4. | 1968 | 5672975 | |
| viscosity study of dna. ii. the effect of simple salt concentration on the viscosity of high molecular weight dna and application of viscometry to the study of dna isolated from t4 and t5 bacteriophage mutants. | 1968 | 5663405 | |
| mutagenic treatment of double- and single-stranded dna phages t4 ans s13 with hydroxylamine. | 1968 | 5663335 | |
| genetic transformation of the bacteriophage t4. 3. | 1968 | 5661361 | |
| the extent of rii deletions in phage t4. | 1968 | 5647634 | |
| genotypic reversion by methylene blue: the orientation of guanine-hydroxymethylcytosine at mutated sites in rii mutants of phage t4. | 1968 | 5646389 | |
| indices during administration of t4 and t3 to euthyroid adults. | 1968 | 5641753 | |
| direction of translation of the lysozyme gene of bacteriophage t4 relative to the linkage map. | 1968 | 5637201 | |
| selective gene transcription in bacteriophage t4 by putrescine. | messenger ribonucleic acid (mrna) preparations from t4-infected cells formed in the presence or absence of putrescine have been characterized and compared. hybrid competition experiments indicate that these mrna molecules are derived from distinct genetic loci. the results are consistent with the hypothesis that putrescine might control differential transcription of the phage genome during morphogenesis. the data are also in accord with previously observed changes in the population of mrna forme ... | 1967 | 5623975 |
| differential effect of polyamines on t4 morphogenesis. | the 5-fluorouracil (5 fu) technique for the phenotypic reversion of amber mutants was used to demonstrate that under certain circumstances, in the presence of putrescine or spermidine, early mutants have an enhanced response to 5 fu, whereas late mutants have a delayed response. bacteria infected by t4d wild-type bacteriophage did not produce phage in the presence of high putrescine concentrations. pulse treatments with putrescine showed that the production of lysozyme depends on a putrescine-se ... | 1967 | 5623974 |
| properties of r mutants of bacteriophage t4 photodynamically induced in the presence of thiopyronin and psoralen. | about 4 x 10(-4)r mutants were induced per lethal hit, a frequency characteristic of weak mutagens. collections of mutants produced in the presence of either dye were indistinguishable in most of their properties. the rii mutants differed sharply from spontaneous mutants in their mutational spectra (fine scale map distribution) and their reversion responses to specific mutagens. few or none of the induced mutants were induced to revert with proflavine (sign mutants; reading frame shift mutants). ... | 1967 | 5623962 |
| further studies on the mutation with glucose oxime: the reaction of the oxime with t4 phage and nucleic acids. | 1967 | 5622070 | |
| molecular recombination in t4 bacteriophage deoxyribonucleic acid. i. tertiary structure of early replicative and recombining deoxyribonucleic acid. | a replicative hybrid resulting from the infection of heavy (substituted with 5-bromodeoxyuridine) bacteria with light (not substituted with 5-bromodeoxyuridine) radioactive bacteriophage was isolated from a cscl density gradient. sedimentation studies indicate that 60% of the deoxyribonucleic acid (dna) behaves as if it were in units more than four times as large as an intact reference molecule. under the electron microscope, hybrid molecules appeared tangled, showed puffs and loops, occupied a ... | 1967 | 5621474 |
| exclusion of rna bacteriophages and interference with their rna replication by bacteriophage t4. | 1967 | 5586930 | |
| damage to deoxyribose molecules and to u-gene reactivation in uv-irradiated 5-bromouracil-dna of phage t4 bor as influenced by cysteamine. | 1967 | 5586533 | |
| increased heterozygote frequency in certain regions of the t4-chromosome. | 1967 | 5586530 | |
| recombination in bacteriophage t4. | 1967 | 5582804 | |
| bacteriophage t4 head morphogenesis. on the nature of gene 49-defective heads and their role as intermediates. | 1971 | 5580436 | |
| hycanthone: a frameshift mutagen. | rapid spot-test screening of antischistosomal agents reveals that hycanthone is a potent frameshift mutagen while the closely related compound, miracil d, is nonmutagenic in salmonella. both hycanthone and miracil d are frameshift mutagens for t4 bacteriophage during growth in escherichia coli. | 1971 | 5573958 |
| morphogenesis of the tail fiber of bacteriophage t4. 3. isolation of the gene 35-product and the genes 36, 37 and 38 product. | 1971 | 5568919 | |
| controls and polarity of transcription during bacteriophage t4 development. | 1971 | 5566419 | |
| alternative pathways of tail fiber assembly in bacteriophage t4? | 1971 | 5566418 | |
| quantitation of extrathyroidal conversion of l-thyroxine to 3,5,3'-triiodo-l-thyronine in the rat. | studies of the rate of extrathyroidal conversion of thyroxine (t4) to 3,5,3'-triiodo-l-thyronine (t3) were carried out in rats. total body homogenates were prepared and extracted with ethanol 48, 72, and 96 hr after the intravenous injection of (125)i-t4. (131)i-t3 was added, and the paper chromatographic purification of t3 was effected by serial elution and rechromatography in three paper and one thin-layer cycles. the ratio of (131)i-t3 and (125)i-t3 counting rates in the final chromatograms, ... | 1971 | 5552409 |
| phospholipid hydrolysis in escherichia coli infected with rapid lysis mutants of phage t4. | 1971 | 5543840 | |
| abortive infection by phage t4 under conditions of defective host membrane lipid biosynthesis. | 1971 | 5543829 | |
| formation of rna in t4 phage-infected bacteria: transcriptional regulation of early enzyme synthesis. | 1971 | 5543828 | |
| the behavior of temperature-sensitive t4 dna polymerase mutants in temperature shift experiments. | 1971 | 5543827 | |
| enzymatic breakage and joining of deoxyribonucleic acid. 8. hybrids of ribo- and deoxyribonucleotide homopolymers as substrates for polynucleotide ligase of bacteriophage t4. | 1971 | 5543691 | |
| mutants in a nonessential gene of bacteriophage t4 which are defective in the degradation of escherichia coli deoxyribonucleic acid. | wild-type bacteriophage t4 was enriched for mutants which fail to degrade escherichia coli deoxyribonucleic acid (dna) by the following method. e. coli b was labeled in dna at high specific activity with tritiated thymidine ((3)h-dt) and infected at low multiplicity with unmutagenized t4d. at 25 min after infection, the culture was lysed and stored. wild-type t4 degrades the host dna and incorporates the (3)h-dt into the dna of progeny phage; mutants which fail to degrade the host dna make unlab ... | 1971 | 5543437 |
| inhibition of t4 bacteriophage multiplication by superinfecting ghosts and the development of tolerance after bacteriophage infection. | simultaneous addition of t4 phage and ghosts to host cells prevents infective center formation. cells which have been infected with phage for less than 2 min are also inhibited by superinfecting ghosts. after this time, a chloramphenicol-inhibitable reaction occurs which causes the phage-infected cells to become increasingly tolerant of added ghosts. | 1971 | 5543436 |
| in vitro synthesis of t4 proteins: control of transcription of gene 57. | 1971 | 5543275 | |
| in vitro synthesis of t4 proteins: the products of genes 9, 18, 19, 23, 24, and 38. | 1971 | 5543273 | |
| the thermal inactivation of t4 and lambda bacteriophage. | thermal inactivation of t(4) and lambda bacteriophage shows two components of differing sensitivity are present. these cannot be interpreted as owing to nucleic acid and protein. one protein function-the inhibition of radiation-induced dna degradation-is lost with quite different thermal kinetics. lambda heated in the presence of dnase is more rapidly inactivated; lambda is also protected by slow cooling after heat. these results suggest that the packing of the dna in the head occurs so as to pe ... | 1971 | 5539000 |
| [serum thyroxine (t4) determination]. | 1970 | 5534708 | |
| determination of gene product positions in bacteriophage t4 by specific antibody association. | 1970 | 5530395 | |
| recombination of bacteriophage t4 stimulated by 9-aminoacridine. | 1970 | 5518506 | |
| [new results on the form inheritance of phage t4]. | 1970 | 5513572 | |
| genetic alterations of the rii b cistron polypeptide of phage t4. | 1970 | 5512468 | |
| on the mechnaism of radiosensitization by 5-bromouracil. the occurrence of dna strand breaks in u.v.-irradiated phage t4 as influenced by cysteamine. | 1970 | 5498540 | |
| incorporation of deoxyribonucleic acid precursors by t4 deoxyribonucleic acid-protein complexes retained on glass fiber filters. | bacteriophage t4 deoxyribonucleic acid (dna)-protein complexes were retained preferentially on glass fiber filters. dna polymerase activity in the complex was detected through the incorporation of (3)h-labeled dna precursors. the primer-product dna hybridized with both phage and escherichia coli dna. density labeling experiments showed that about 30% of incorporated (3)h-deoxyadenosine triphosphate was found in dna which hybridized with phage dna; this dna was found to be covalently attached to ... | 1970 | 5497903 |
| determination of the mutagenic activity to bacteriophage t4 of carcinogenic and noncarcinogenic compounds. | 1970 | 5497717 | |
| morphogenesis of the tail fiber of bacteriophage t4. ii. isolation and characterization of a component (the genes 35-36-37-38 directing half fiber). | 1970 | 5497289 | |
| a semiautomated method for the determination of serum thyroxine (t4) without incineration. | 1970 | 5496579 | |
| frameshift mutation in the lysozyme gene of bacteriophage t4: demonstration of the insertion of five bases, and a summary of in vivo codons and lysozyme activities. | 1970 | 5494033 | |
| structural proteins of bacteriophage t4. | 1970 | 5493282 | |
| morphogenesis of the tail fibre of bacteriophage t4: isolation and characterization of a component (the gene 34 product). | 1970 | 5492612 | |
| polysomal distribution of late bacteriophage t4 messenger rna. | 1970 | 5492611 | |
| polynucleotide kinase mutant of bacteriophage t4. | 1970 | 5491724 | |
| initiation of the polypeptide chain in the rii b cistron of bacteriophage t4. | 1970 | 5485909 | |
| the size of the rii region of bacteriophage t4. | 1970 | 5483264 | |
| bacteriophage t4 mutants unable to exclude gene 56 of t2 from the progeny of crosses. | 1970 | 5480478 | |
| adjacent effect on suppression efficiency. ii. study on ochre and amber mutants of t4 phage lysozyme. | 1970 | 5480467 | |
| effects of 9-aminoacridine on bacteriophage t4 deoxyribonucleic acid synthesis. | 1970 | 5476916 | |
| kinetics and intermediates in the intracellular synthesis of bacteriophage t4 deoxyribonucleic acid. | 1970 | 5476915 | |
| properties of bacteriophage t4 mutants defective in dna polymerase. | 1970 | 5474826 | |
| the amino acid sequence of t4 phage lysozyme. iv. dilute acid hydrolysis and the order of tryptic peptides. | 1970 | 5470817 | |
| the amino acid sequence of t4 phage lysozyme. ii. chymotryptic digestion. | 1970 | 5470816 | |
| the amino acid sequence of t4 phage lysozyme. i. tryptic digestion. | 1970 | 5470815 | |
| in vitro induction of a primary response to the dinitrophenyl determinant. | primary antibody response against the dinitrophenyl group has been elicited in vitro after the stimulation of normal mouse spleen explants with 2,4-dinitrophenyl (dnp)-hemocyanin or alpha-dnp-poly-l-lysine (pll). antibodies were detected in the culture medium by the inactivation of dnp-t4 phage. the specificity of the reaction was manifested by the lack of the capacity of the medium to inactivate the unmodified bacteriophage and by the inhibition of the inactivation of dnp-t4 with dnp-lysine. | 1970 | 5460614 |
| replacement of all tryptophan residues in t4 bacteriophage lysozyme by tyrosine residues. | 1970 | 5460304 | |
| t4 bacteriophage gene 32: a structural protein in the replication and recombination of dna. | 1970 | 5455134 | |
| the effects of ultraviolet irradiation on the transcription of t4 dna. | 1970 | 5453524 | |
| effect of x-irradiation on gene function in bacteriophage t4. | 1970 | 5451815 | |
| form-determining function of the genes required for the assembly of the head of bacteriophage t4. | 1970 | 5450520 | |
| rates of bacteriophage t4 rna chain growth in vitro. | 1970 | 5450516 | |
| temporary arrest of maturable precursor synthesis in some temperature-sensitive mutants of phage t4. | 1970 | 5450389 | |
| conversion of thyroxine to triiodothyronine in normal human subjects. | the conversion of thyroxine to triiodothyronine, previously demonstrated in athyreotic human subjects, has been investigated in normal subjects who were given intravenous injections of purified thyroxine labeled with carbon-14 in ring a and in the alanine side chain. evidence for the conversion of t4 to t3 was provided by the finding of carbon-14 in the t3 fraction isolated from serums. it is estimated that an appreciable fraction of t4 may be transformed to t3 in normal man. | 1970 | 5449321 |
| relationship between gene 55 function, late transcription and an intermediate in the replication of bacteriophage t4 dna. | 1970 | 5447829 | |
| function of t4 gene 55. ii. rna synthesis by temperature-sensitive gene 55 mutants. | 1970 | 5447828 | |
| function of t4 gene 55. i. characterization of temperature-sensitive mutations in the "maturation" gene 55. | 1970 | 5447827 | |
| transcription during bacteriophage t4 development: a demonstration that distinct subclasses of the "early" rna appear at different times and that some are "turned off" at late times. | 1970 | 5447821 | |
| control of translation of t4 phage: altered ribosome binding at r17 initiation sites. | 1970 | 5444624 | |
| control of translation by t4 phage: altered binding of disfavoured messengers. | 1970 | 5444623 | |
| a factor required for the translation of bacteriophage f2 rna in extracts of t4-infected cells. | 1970 | 5443705 | |
| differences in primary cellular factors influencing the metabolism and distribution of 3,5,3'-l-triiodothyronine and l-thyroxine. | administration of phenobarbital, which acts exclusively on cellular sites, results in an augmentation of the liver/plasma concentration ratio of l-thyroxine (t4) in rats but no change in the liver/plasma concentration ratio of l-triiodothyronine (t3). whereas phenobarbital stimulates the fecal clearance rate both of t3 and t4, it increases the deiodinative clearance rate of t4 only. these findings suggest basic differences in the cellular metabolism of t3 and t4. further evidence pointing to cel ... | 1970 | 5441537 |
| natural occurrence of cross-linked vaccinia virus deoxyribonucleic acid. | the molecular weight of native vaccinia deoxyribonucleic acid (dna) is 1 to 1.17 times that of native t4 dna. sedimentation of denatured vaccinia dna through alkaline sucrose gradients yields an apparent molecular weight greater than twice that of denatured t4 dna, implying that the complementary strands of vaccinia dna do not separate upon denaturation. when alkali-denatured vaccinia dna is neutralized, it has the physical chemical properties of native dna when tested by sedimentation through n ... | 1970 | 5438108 |
| the lysis mechanism of phage t4: mutants affecting lysis. | 1970 | 5437792 | |
| sensitized photoinactivation of bacteriophage t4. | 1970 | 5435554 | |
| cleavage of structural proteins during the assembly of the head of bacteriophage t4. | 1970 | 5432063 | |
| disappearance of 131 i-labeled thyroxine (131 i-t4) from agar pellets implanted in the hypothalamus of rats. | 1970 | 5423321 | |
| inactivation of urea-treated phage t4 by phosphatidylglycerol. | 1970 | 5422724 | |
| phenotypic reversion by hydroxylamine. a new group of suppressible phage t4 rii mutants. | 1970 | 5422475 | |
| deficiency of double mutant recombinants in crosses of phage t4. | 1970 | 5415251 | |
| a factor preventing the major head protein of bacteriophage t4 from random aggregation. | 1970 | 5413343 | |
| requirement for cellular interaction in the antibody response to bacteriophage t4 in mice. | 1970 | 5411502 | |
| mutagenic effect of a carcinogen, 4-nitroquinoline 1-oxide, in bacteriophage t4. | 1970 | 5410806 | |
| rna polymerase and the shut-off of host rna and protein synthesis in t4 phage infection. | 1970 | 5410196 | |
| [the activity of each of the dna chains of t4 phage in genetic recombination]. | 1969 | 5398946 | |
| assembly of bacteriophage t4 tail fibers: the sequence of gene product interaction. | 1969 | 5390559 | |
| the immunogenicity of phagocytosed t4 bacteriophage: cell replacement studies with splenectomized and irradiated mice. | 1969 | 5370054 | |
| the actvity of mouse kupffer cells following intravenous injection of t4 bacteriophage. | 1969 | 5370053 | |
| genetic determinant of an internal peptide of bacteriophage t4. | 1969 | 5365956 | |
| the lysozyme of a triple frame-shift mutant strain of bacteriophage t4. | 1969 | 5365013 | |
| attachment of tail fibers in bacteriophage t4 assembly: some properties of the reaction in vitro and its genetic control. | 1969 | 5357214 | |
| bacteriophage t4 lysozyme mrna. | 1969 | 5345400 |