Publications

prolonged human cytomegalovirus viremia following bone marrow transplantation.		1984	6322392
trace nitrogenous species in urban atmospheres.	recent results concerning the identification and measurement of nitrogenous air pollutants in the california south coast air basin (cscab) are presented. in planning or evaluating studies of the human health effects of these pollutants, it is important to consider the entire range of species which may be present. we provide estimates of typical exposures to nitrogenous air pollutants during a single day oxidant event in the cscab.	1983	6317372
preventing rhesus isoimmunization. antepartum rh immune globulin prophylaxis versus a sensitive test for risk identification.	the controversial proposal to use rho (d) immune globulin (human) prophylactically in pregnancy should not detract from the most expedient approach to further reduction of rh disease; that is, to ensure that every eligible woman is given rho (d) immune globulin (human) after delivery, abortion, or ectopic pregnancy. family planning by rh-negative women at risk and limiting the number of pregnancies in women already immunized will be additional effective ways to reduce the current incidence of he ...	1983	6307052
emergence of california encephalitis as a continental epidemiological, virological, and human disease problem.		1983	6306692
adenovirus type 7b in a children's hospital.	between august 15 and september 15, 1980, an outbreak of infections due to adenovirus type 7b occurred at children's hospital and health center, san diego, california. during that time, four of six patients infected with adenovirus type 7b died. all patients with hospital-acquired disease had underlying respiratory compromise. cultures, adenoviral serology tests, and histories were obtained from 383 (93%) of the 410 hospital employees. all 11 people from whom adenovirus type 7 was cultured were ...	1983	6302176
prevalence of antibodies of selected infectious disease agents in the peninsular desert bighorn sheep (ovis canadensis cremnobates) of the santa rosa mountains, california.		1982	6285010
children during residency: it's easier if you're a man.		1981	6265534
procedure for recovery of enteroviruses from the japanese cockle tapes japonica.	the most likely shellfish to be harvested if sportfishing is reinstated in san francisco bay is the japanese cockle tapes japonica. the virus levels present in these shellfish are unknown and need to be evaluated before the shellfish beds are open. towards this end, a procedure for recovering and concentrating enteric viruses from these clams has been evaluated. effective elution of poliovirus from clam tissues was found to occur with ph 9.5 glycine-buffered saline rather than with the ph 7.5 fl ...	1981	6263186
recent advances in occupational cancer.	the contribution of occupational and environmental exposures to the etiology of cancer is a topic of considerable scientific and public interest. if an occupational environmental exposure is associated with cancer in man, then both the exposure and the disease are preventable by appropriate protection. in order to enhance the awareness and timeliness of new information concerning occupational cancer, the university of california, san francisco, school of medicine in conjunction with the northern ...	1984	6209421
isolation of lymphocytopathic retroviruses from san francisco patients with aids.	infectious retroviruses have been detected in 22 of 45 randomly selected patients with acquired immune deficiency syndrome (aids) and in other individuals from san francisco. the aids-associated retroviruses (arv) studied in detail had a type d morphology, mg2+-dependent reverse transcriptase, and cytopathic effects on lymphocytes. the viruses can be propagated in an established adult human t cell line, hut-78. they cross-react with antiserum to the lymphadenopathy-associated retrovirus isolated ...	1984	6206563
jamestown canyon virus: the etiologic agent of an emerging human disease?		1983	6191343
relevance of biochemical tumor markers and lymphadenectomy in management of non-seminomatous testis tumors: current perspective.	radioimmunoassay determinations of the biochemical tumor markers, alpha-fetoprotein or human chorionic gonadotropin, revealed elevated serum levels in 94 per cent of the patients with advanced disease. no falsely positive values have been observed. the markers are useful in monitoring the response to therapy and, when persistently elevated after therapy, indicate the presence of residual malignant tumor, usually embryonal carcinoma. however, they have a more limited role in the management and fo ...	1980	6153725
historical perspectives on california encephalitis virus in california.	cev is primarily associated with ae. melanimon as its maintenance host and vector in california. a few species of lagomorphs and rodents will develop a transient viremia when infected. infection of domestic mammals and man is frequent but rarely results in a clinical disease. extensive field and laboratory studies lead to the conclusion that cev probably is a mosquito virus that is partially adapted to a narrow range of vertebrate hosts but is not reliant on vertebrates for its continuous existe ...	1983	6135217
epidemic of acquired immunodeficiency in rhesus monkeys.	a syndrome closely resembling acquired immunodeficiency syndrome (aids) in man has been identified in a group of 64 rhesus monkeys (macaca mulatta) maintained outdoors at the california primate research center. the syndrome is characterised by generalised lymphadenopathy, severe opportunistic infections including cytomegalovirus, chronic wasting, and high mortality. in 1 animal a multifocal cutaneous fibrosarcoma developed. this syndrome in monkeys may provide an animal model for human aids.	1983	6130381
outbreak of burkitt's-like lymphoma in homosexual men.	four cases of burkitt's-like lymphoma (undifferentiated, monoclonal, b-cell tumours) in homosexual men were seen in a 9-month period in san francisco. one tumour contained both epstein-barr-virus nuclear antigen (ebna) and cytomegalovirus (cmv) antigen. another tumour contained ebna, and a third contained no viral antigen, but ebna and cmv antigens were detected in the overlying epithelium. this outbreak widens the array of neoplasms affecting immunosuppressed homosexual men and provides further ...	1982	6125777
an "ever-widening gap" between rich and poor.		1981	6119973
genetic control of the human immune response. proceedings of a conference sponsored by the kroc foundation, santa ynez valley, california, 28 january-1 february 1980.		1980	6106037
alcohol, smoking, and incidence of spontaneous abortions in the first and second trimester.	32,019 women completed a questionnaire on alcohol use at their first antenatal visit; thereafter they were followed to assess the incidence of spontaneous abortions. 51.7% reported drinking no alcohol in early pregnancy; 44.7% had less than 1 drink daily; and 2.4, 0.4, and 0.1% had an average of 1-2, 3-5, or more than 6 drinks respectively. life-table analysis showed that the age-adjusted relative risks of second-trimester losses (15-27 weeks) were 1.03 (not significant: ns), 1.98 (p < .01), and ...	1980	6105340
proceedings of a conference on pancreas transplantation: toward transplantation of the human pancreas. los angeles, california, june 8 and 9, 1979.		1980	6101563
possible heterogeneity in the phosphoglycolate phosphatase (pgp)-haptoglobin alpha (hpa) linkage.	previous investigators have reported loose linkage in both sexes for phosphoglycolate phosphatase (pgp) and haptoglobin alpha (hpa). we present results of linkage studies between pgp and hpa in two data sets, one from houston and the other an update of an earlier report from los angeles. using quadratic interpolation to estimate the male (theta m) and female (theta f) recombination values from bivariate lod tables, we found for the houston data that theta m = 0.43 and theta f = 0.03 at the maxim ...	1984	6089552
prevalence of delta agent among chinese in taiwan and los angeles.	the prevalence of delta agent among 120 chinese patients with hbsag-positive chronic active and hepatocellular carcinoma from taiwan and los angeles were studied by serological assay for antibody to delta antigen and immunoperoxidase staining for delta antigen in the liver biopsies. of 120 patients, only four with chronic active hepatitis and one with hepatocellular carcinoma from taiwan had antibody to delta antigen in their sera, while none was detected in the patients from los angeles. indire ...	1984	6086830
evaluation of pesticides which pose carcinogenicity potential in animal testing. ii. consideration of human exposure conditions for regulatory decision making.	in reaching a regulatory decision on the use of pesticides with carcinogenic potential, it is of great importance to investigate the extent of dermal exposure and absorption of a pesticide to users and field workers. by applying this information, along with the appropriate carcinogenicity categorization of a pesticide, a reasonably sound regulatory decision can be derived. seven pesticides were selected, based on adequacy of tumor data, and were taken through the tumor evaluation system as repor ...	1984	6084262
public health report.		1967	6039190
snipe flies (symphoromyia) attacking man and other animals in california.		1966	5964229
the function of the well man clinic.		1966	5936993
changes in human body burdens of gamma-radioactivities, 1960-64.		1965	5898802
evaluation of the teratogenic effect of meclizine in man.		1965	5891549
strontium-90 in human vertebrae, 1964 results.		1965	5841951
evaluation of monovalent influenza vaccine in a retirement community during the epidemic of 1965-66.		1969	5819227
protective effect of influenza immunization: the "hong kong flu" epidemic.		1969	5818804
vector and nuisance problems emanating from man-made recreational lakes.		1968	5753375
cancer in households. a human-canine retrospective study.		1968	5750120
strontium-90 in human vertebrae, 1967.		1968	5721317
strontium-90 in human vertebrae, 1967.		1968	5702094
human tear lysozyme. 3. preliminary study on lysozyme levels in subjects with smog eye irritation.		1968	5659314
efficiency and the public's health.	the governor's survey on efficiency and cost control, established by governor reagan's executive order, was a non-profit, bipartisan, privately financed management analysis of state administration conducted by private citizens, including physicians, during 1967 for the purpose of achieving improvement in administrative procedure and operating economies in state government. state employees and appointed department heads offered many valuable suggestions and cooperated fully with the survey team. ...	1968	5652763
human tooth wear, tooth function and cultural variability.		1971	5572602
cerumen genetics and human breast cancer.	international mortality and frequency rates for breast cancer seem to be associated with the frequency of the allele for wet-type cerumen. a preliminary retrospective case-control study in california indicates that phenotypically wet-type cerumen is found in japanese women with breast cancer more often than in healthy japanese women. findings support the hypothesis that the apocrine system's genetically determined variation may influence susceptibility to breast cancer.	1971	5559907
chronic oxidant exposure and epidemic influenza.		1971	5556100
studies on respiratory disease at fort ord, calif., 1957-1968.		1970	5504434
137cs levels in human adult population in california, 1960-69.		1970	5479527
ethics of ethical evaluation.		1970	5467008
emerging assets and liabilities of a committee on human welfare and experimentation.		1970	5467006
hydatid disease in the central valley of california. transmission of infection among dogs, sheep, and man in kern county.		1970	5465773
human sexuality--a program for sex education in the public school system.		1970	5435883
consultation with police on human relations training.		1970	5434624
influenza 1968--a2-hong kong-68.		1970	5430507
influenza 1968--a2-hong kong-68.		1970	5429132
dialects in elephatn seals.	threat vocalizations of male elephant seals mirounga angustirostris vary among four populations on islands off the coast of california and baja california, mexico. males at san nicolas island in southern california emit sound pulses at more than double the rate of males at aũo nuevo island, 528 kilometers north. mean pulse rates at san miguel island and isla de guadalupe (408 and 944 kilometers south of aũo nuevo, respectively) are intermediate to these two. pulse rate is homogeneous within each ...	1969	5360593
studies with inactivated influenza vaccines purified by zonal centrifugation. 2. efficacy.	high (3000 cca units) and standard low (300 cca units) doses of the monovalent purified vaccines described in an earlier paper were evaluated in a double-blind manner in 2 adult populations for protective effectiveness against illness caused by the hong kong influenza virus. epidemics in both populations occurred 4-6 weeks after single injections of vaccine were given.the attack rates among recipients of low or high doses of a2/japan vaccines in a prison were virtually identical to those among t ...	1969	5309468
a model for cesium-137 body burdens in man. la-3848-ms.		1968	5302799
the population variance of the proportion of genetic admixture in human intergroup hybrids.	for each individual in a human hybrid population there is a proportion mu(i), whose value is usually unknown, that expresses the fraction of his genes deriving from a specified parental population. the distribution of these individual proportions about the mean proportion mu is not known for any large hybrid population in man. it is of interest to know whether the population variance of individual proportions (mu(i)) can be estimated from the variation between different, independent estimates of ...	1971	5289254
kern county: annual generic pesticide input; blood dyscrasias; p,p'-dde and p,p'-ddt residues in human fat, placentas with related stillbirths and abnormalities.		1968	5243486
research program.		1970	5201746
strontium-90 in human vertebrae. results for 1968. hasl-210.		1969	5196636
group performance and control; county of los angeles health department.		1969	5196422
strontium-90 in human vertebrae--1967 results. hasl-197.		1968	5188572
strontium-90 in human vertebrae. 1966 results. hasl-182.		1967	5187197
aim-twx service at the university of virginia: a review and evaluation.	the paper reviews the highlights of a four-week trial period (november 19-december 18, 1970) during which the medical library of the university of virginia experimented with a new remote-access bibliographical control and retrieval system via its twx machine. the system, called aim-twx, was sponsored by the lister hill national center for biomedical communications and utilizes a timeshared ibm 360/67 computer in santa monica, california. citations from 109 clinically-oriented journals from 1966 ...	1971	5172472
liability from experiments.		1971	5115842
q fever in los angeles county. serological survey of human and bovine populations.	q fever is endemic and enzootic in los angeles county. a serological survey conducted in 1949 is compared with a current survey. infection in dairy herds is now almost universal, while the prevalence of positive complement fixation titers in man only increased from 1.2 percent to 2.3 percent (p <0.10). the relative stability in man is accounted for by the increase in temperature requirements for milk pasteurization, the decrease in consumption of raw milk and the decrease in the number of dairy ...	1971	5100502
enlarging human capability: the central role of the health sciences.		1972	5087139
rescheduling to save housekeeping man-hours.		1972	5084918
artificial vs breast feeding: relation to infant health in a middle class american community.	the effects of breast feeding in the early months of life on such clinical phenomena as the rate of weight gain, linear growth, frequency of office visits, phone calls and types of clinical morbidity encountered in office practice during the 1st year of the infant's life were examined. the practice was located in a suburban california residential area. this report is based on observations of 113 consecutive infants seen from birth through the 1st year each with at least 4 well-check visits inc ...	1972	5066890
nonhighway injury fatalities. ii. interaction of product and human factors.		1972	5027331
strontium-90 in human vertebrae, 1968, 1969, and 1970.		1972	5015505
vitamin a concentration in human tissues collected from five areas in the united states.		1972	5011912
human paleopathology and some diseases in living primitive societies: a review of the recent literature.		1969	4984307
human immunity to the meningococcus. i. the role of humoral antibodies.	susceptibility to systemic meningococcal disease is related to a selective deficiency of humoral antibodies to pathogenic strains of meningococci. in a study of the age-specific incidence of meningococcal meningitis in the united states, it was found that the proportion of individuals with serum bactericidal activity to meningococci of serogroups a, b, and c was reciprocally related to the incidence of disease. the prevalence of bactericidal activity was highest at birth and among adults, and lo ...	1969	4977280
use of telephone interviewing to study human reproduction.		1968	4972413
the growing importance of california arboviruses in the etiology of human disease.		1971	4950607
a two-year experience with human heart transplantation.	during the first two years of clinical cardiac transplantation 20 patients had the operation at stanford. operative techniques were successfully translated from extensive laboratory experience to clinical application. operative indications and contraindications were defined. the diagnosis and treatment of acute cardiac rejection were successful in most cases. infection, unremitting acute rejection, and chronic rejection remain the major problems in clinical cardiac transplantation. in 20 patient ...	1970	4950508
results of human heart transplantation at stanford university.		1971	4937901
human babesiosis in ireland: further observations and the medical significance of this infection.	three splenectomized persons in yugoslavia, california, and ireland have been reported to be infected by three different babesia species; two cases were fatal. in a study of the site where the fatal infection was contracted in ireland, blood samples from 36 persons who had recently been bitten by ticks were inoculated into two splenectomized calves; no response to babesia divergens was detected. field-collected ixodes ricinus ticks inoculated into another splenectomized calf resulted in fever an ...	1969	4902496
a man to match a mountain. carleton mathewson, jr. at the university of california.		1969	4898190
experiments with human subjects.		1969	4893567
the epidemiology of cancer in animals.	the principles of epidemiology are applicable to the study of the distribution and determinants of cancer in both human and animal populations. there are many examples of epidemiologic factors (host, environment, agent and time) related to cancer in animals. certain host characteristics such as age, sex and breed are related to risk of developing cancer. some environmental influences are illustrated by differences in the geographical distribution of certain types of animal cancer. aggregations o ...	1967	4865378
the epidemiology of influenza in california, 1968-1973.	influenza is one of the most common acute febrile respiratory diseases in adults. epidemics caused by influenza viruses occur every few years. when such epidemics are in progress, the medical community, the general public and the news media seek information regarding the presence, spread and severity of influenza. the methods and findings of the influenza surveillance system in california for the years 1968 through 1973 should be of interest generally. this period spans the total california expe ...	1974	4847436
antimicrobial resistance and r factors in salmonella isolated in california (1971-1972).	the antimicrobial resistance of 2,246 strains of salmonella isolated from humans in california was determined. resistance to one or more of the 12 antimicrobial agents tested was found in 32% of the isolates. salmonella typhimurium strains represented 31% of the serotypes isolated; 49% of these strains were resistant. fifty-one percent of s. heidelberg, 42.5% of s. newport, and 40% of s. saint paul strains were resistant. seventy-seven percent of all resistant serotypes were resistant to two or ...	1974	4840429
institutions in modern society: caretakers and subjects.	the problems that relate to the outermost limits of institutional care, if such limits exist, will certainly be among the most salient problems during the coming years-no matter whether such care proceeds on an inpatient or an outpatient basis. whatever course may be taken will certainly affect the lives of every citizen in urbanized and industrialized society. at present in california there is considerable shifting of individuals from one care status or category to another, in efforts to find a ...	1974	4821239
human infection with vibrio fetus.	vibrio fetus, a slowly growing, microaerophilic, gram-negative rod which causes infectious abortion in cattle, occasionally induces disease in man. since persons receiving immunosuppressive agents are among those most susceptible to this infection, recognition of the disease may become increasingly important as transplantation operations increase. vibrio infections may produce a spectrum of acute and chronic illnesses or may be asymptomatic. vibriosis may develop at any age but it seems most dev ...	1974	4816399
a new variant of galactose-1-phosphate uridyltransferase in man: the los angeles variant.		1973	4759900
informed consent, a reappraisal of patients' reactions.	in response to the november 1972 ruling of the california supreme court requiring complete, detailed disclosure of risks for procedures and treatments, a survey was made of the reactions of one hundred patients to this decision. a fictional man was described with a clinical diagnosis of brain tumor, and then the procedure for cerebral angiography and all of that procedure's potential complications were described. the majority of the patients surveyed responded that this complete disclosure of ri ...	1973	4755699
arboviruses in finland. v. serological survey of antibodies against inkoo virus (california group) in human, cow, reindeer, and wildlife sera.		1973	4729744
research on human subjects. the developing law.		1973	4714260
motor vehicle accidents: human causes and injuries sustained. an in-depth study of 35 accidents.		1973	4710838
mercury in human hair. a study of the residents of los alamos, nm, and pasadena, calif, by cold vapor atomic absorption spectrophotometry.		1973	4709110
admixture studies and the detection of selection.	three methods can be used to search for evidence of natural selection from admixture studies. these include classification of the admixture estimates into two groups; calculation of the rank correlation between estimates from more than one population; and the testing of admixture estimates for homogeneity. the use of these methods is discussed with special reference to black-white admixture in the united states. using revised estimates of african gene frequencies, derived from a consideration of ...	1973	4707061
human accountability in a community mental health center: report of an automated system.		1972	4669433
community diagnosis: an analysis of indicators of health and disease in a metropolitan area.		1972	4669184
new evidence for the antiquity of man in north america deduced from aspartic acid racemization.	ages of several californzia paleo-indlian skeletons have been deduced from the extent of aspartic acid racemization. these dates suggest that man was present in north america at least 50,000 years before the present.	1974	4595240
a case of human rabies with prolonged survival.		1973	4589643
serologic diagnosis of toxoplasmosis and prevalence of toxoplasma gondii antibodies in selected feline, canine, and human populations.		1973	4574472
[patient evaluation prior to clinical studies performed at the san francisco campus of university of california].		1974	4479972
schistosomiasis mansoni in yemeni in california: duration of infection, presence of disease, therapeutic management.	investigations of schistosomiasis mansoni in 218 yemeni agricultural workers in the san joaquin valley of california revealed a prevalence of 56%. in those infected, quantitative egg counts performed by the kato thick smear method revealed that 57% had light infections (1-100 eggs/g), 27% moderate infections (101-400 eggs/g), and 16% heavy infections (greater than 400 eggs/g; mean--918 eggs/g). the yemeni had been migrating to the usa for the past 20 years, a period in which the prevalence of sc ...	1974	4451230
hierarchical computer systems for on-line applications.		1974	4435249
strontium-90 in human vertebrae, 1972.		1974	4428002
lead concentrations in human milk.		1974	4414068
california encephalitis virus: serological evidence of human infections in alaska.		1972	4402443
genetic control mechanisms in man and other mammals.		1970	4393493