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the effects of cholera enterotoxin on intestinal tissue water as measured by nuclear magnetic resonance (nmr) spectroscopy.cholera enterotoxin has been postulated to change the configuration of the intracellular protein-water system, altering the permeability of the cell to water. using nuclear magnetic resonance (nmr) spectroscopy, this protein-water relationship can be examined. small intestinal loops in the rat were injected with 0.5 ml of either schwarz/mann cholera enterotoxin (40 mug/cc saline solution) or normal saline. full thickness segments of intestine from each loop were taken and percentage water (using ...19751223921
[ecg characteristics during its recording from electroanomalous points of the skin]. 19751223350
[peridural analgesia in obstetrics. apropos of 165 cases]. 20051221888
cell-wall antigens of v. cholerae and their implication in cholera immunity. 19751219915
virulence-enhancing effect of ferric ammonium citrate on vibrio cholerae. 19751219909
bacteriology at the periphery of the cholera pandemic. 19751219904
the antibody basis of local immunity to experimental cholera infection in the rabbit ileal loop. 19751219901
interbiotype conversion of cholera vibrios by action of mutagens. 19751219900
recent studies on genetic recombination in vibrio cholerae. 19751219899
althesin and pancuronium in chronic liver disease.in 32 patients with chronic liver disease, undergoing major abdominal surgery, anaesthesia was induced with either althesin (alphaxalone and alphadolone acetate) or thiopentone, and maintained with nitrous oxide, oxygen and increments of either pethidine or fentanyl. the patients were ventilated artificially to maintain paco, values in the normal range. pancuronium bromide was used as the muscle relaxant. liver function tests at 24 hr and 5 day after surgery showed only minor changes compared wi ...19971218149
[electron microscopy of cholera vibrios from the intestinal contents of infected suckling rabbits].electron microscopic study of the cells of classic, el tor and nag-vibrios showed them to be no different by the structure type from the cells of ofter gram-negative bacteria. a characteristic peculiarity of the cholera vibrios revealed after their passage through the intestine of nursling rabbits was the presence of microcapsules and protrusions of the areas of the wall membranous apparatus.19751217357
[obstetric complications in the ehlers-danlos syndrome].after discussing the so-called ehlers-danlos syndrome in connection with pregnancy and birth, we report on a complication, turning out deadly for mother and child. futheron, we discuss the appropriate control of pregnancy and birth.19961217253
[amiloride (nilurid, m.s.d.)]. 19791216361
[skin diseases caused by cocci]. 20051214698
[salmonellosis carrier state]. 19751214656
[electron microscopic study of double infection induced by potato virus x and potato virus y in nicotiana glutinosa]. 19751214639
[formation of fatty acids by aspergillus ochraceus 15b growing on a hexadecane containing medium]. 19751214637
[antimicrobic properties of facultative anaerobes isolated from oil-bearing wells]. 19751214635
[changes in the composition of intracellular lipids and hydrocarbons in candida tropicalis in the absence of growth].the fatty acid composition of lipids and the composition of hydrocarbons were studied in candida tropicalis cultivated on a medium with propionic acid and incubated in the conditions of starvation and on a medium containing glucose-1-6-14c but no nitrogen. intracellular fatty acids with an odd number of carbon atoms were found to be easily metabolized by yeast cells. the content and composition of intracellular hydrocarbons were very labile and underwent intensive transformation caused by change ...19751214607
chest wall distortion and regional lung volume distribution in erect humans.using 133xe measured the regional distribution of frc and of boluses administered at frc in seated subjects during relaxation, lateral compression of the lower rib cage, and contraction of the inspiratory muscles so that mouth pressure was 50 cmh2o subatmospheric. lateral compression increased apex-to-base differences of volume and bolus distribution, suggesting an increase of the apex-to-base gradient of pleural surface pressure. changes in rib cage shape were measured with magnetometers and we ...19791213958
studies on bacteriology of cholera infection in varanasi. 19751213804
studies on the so-called nag vibrios. 19751213771
[comparative study of the epidemiology of cholera and sensitivity to antibiotics of strains collected during the epidemiological period in 1971 and 1972 in wilaya de constantine]. 19751213515
selective chemical changes of gonadotropic hormones by means of neuraminidase from vibrio cholerae.experiments indicate that neuraminidase from vibrio cholerae selectively cleaves sialic acid derivate from fsh, but leaves the lh sialic acid derivative. by performing a specific test for lh - the oaad test - we found that the lh activity is not influenced by the presence of neuraminidase. the fsh activity is destroyed by neuraminidase but the enzyme itself influences the ovarian weight, resulting in a weight decrease observed 48 hours after injection. before or after this "critical time" no dec ...19751212991
a salmonella california contamination of a turkey feed concentrate. 19751212606
[role of neuraminidase from cholera vibrions in the pathogenesis of experimental cholera].a study was made of a possible effect of neuraminidase of cholera vibrios on cholera pathogenesis. it was shown that in intraintestinal injection of cholera vibrios of the el tor biotype to nursling rabbits neuraminidase could be revealed in their intestine 5 to 8 hours after the infection. addition of neuraminidase to the weakly cholerogenic strain cholera vibrios intensified its cholerogenic action in infection of the animals. the antineuraminidase serum administered to the infected rabbits pr ...19751210912
[utilization of serological methods in the retrospective diagnosis of cholera and in detecting vibrion carriers].sensitivity and specificity of the three serological methods were studied comparatively: the vibriocidal test, the reaction of bacterial agglutination and of indirect hemagglutination, with the use of erythrocytes sensitized with the vibrio lyzate, cholera species o-antigen and cholerogen. investigations were conducted with the blood sera of cholera patients, vibrio carriers and contacts. vibriocidal test proved to be the most sensitive; its data correlated with the results of bacterial agglutin ...19751210898
abortifacient effects of vibrio cholerae exo-enterotoxin and endotoxin in mice.to study antifertility properties of microbial toxins, exoenterotoxin and endotoxin from vibrio cholerae were injected intravenously into mice at different times during pregnancy. the two substances induced termination of pregnancy, but the patterns of abortifacient activity were different. exotoxin terminated pregnancy in mice when administered between days 4 and 10 of gestation, but abortifacient activity was reduced in animals more than 10 days pregnant; exogenous progesterone did not protect ...19751206628
growth inhibition of vibrio cholerae by d-camphor. 19751206376
protein reagent modification of cholera toxin: characterization of effects on antigenic, receptor-binding and toxic properties.the effects of protein modification procedures on the biologically most important properties of cholera toxin, i.e. the toxic activity, the gm1 receptor-binding capacity and the antigenic (antibody-fixing) properties, have been studied quantitatively using microgram amounts or less of toxin protein. most of the 24 group-specific reagents used had either no inhibitory effect on the toxic or the combination of gm1-binding and antibody-fixing properties of cholera toxin, or they had a concomitant i ...19751206372
rapid and reliable preparation of macroaggregated albumin suitable for lung scintigraphy. 19751205665
comparison of the rate of absorption and proteolysis of [14c]choleragen and [14c]bovine serum albumin in the rat jejunum.[14c]choleragen was used to study the rate of disappearance of choleragen enterotoxin from the jejunum of rats. [14c]bovine serum albumin (bsa) was studied in a similar manner. almost one-third of the labeled toxin had disappeared from the intestine after 6 h. its rate of disappearance was the same in germfree rats as in conventional rats. the rate of proteolysis of [14c]choleragen and [14c]bsa by intestinal mucodal lysosomal enzymes was also studied. neither was significantly degraded by neutra ...19751205622
pinocytic activity in neuraminidase treated ameba. 19751205516
immunoglobulin synthesis and antibody content in the small intestine of the rabbit.the concentration of immunoglobulin and specific antibody in the serum and the intestinal fluid and the rate of synthesis of immunoglobulin in the small intestine was measured in normal and immunized rabbits. iga was found to be the predominant immunoglobulin in the intestinal fluid. iga and igg were secreted at rates of 4-3 mug/cm/hr and 1-3 mug/cm/hr respectively. specific anti-vibrio cholerae antibodies in the intestine were found mainly in the iga class after oral immunization.19751204251
comparative study of the smooth muscle contractor activity of airborne dusts and of dustiness in cotton, flax, and jute mills.a bioassay technique using isolated guinea-pig ileum was employed to compare the smooth muscle contractor activity of various dusts from mills in which the prevalence of byssinosis was known. the activity of dust from a mill spinning a coarse grade of cotton was several times greater than that in dust from a mill processing a fine grade of cotton. there was a similar order in the difference of the prevalence of byssinosis in these mills. however, the activities of fine cotton, flax, and jute dus ...19751201255
detection of haemophilia carriers. 20051201252
ultrastructural studies of the bone marrow in sickle cell anaemia. ii. the morphology of erythropoietic cells and their response to deoxygenation in vitro.electron microscopic studies of bone marrow aspirates obtained from patients with homozygous sickle cell anaemia (hbss) were fixed immediately without attempts to deoxygenate the samples. erythroblasts and normoblasts in these preparations were devoid of haemoglobin polymers or other indications of sickling. furthermore, the nucleated erythroid cells from sickle-cell patients presented an ultrastructural morphology indistinguishable from that of identically-processed erythroid cells in marrow sa ...19751201249
binding of vitamin b12--rat transcobalamin ii and free vitamin b12 to plasma membranes isolated from rat liver.when dialysed rat serum which contains a single, low molecular weight binder for vitamin b12, rat transcobalamin ii (rat tc-ii), was labelled in vitro with 57co-vitamin b12 and then incubated at 30 degrees c (ph 7-5) with vesicles of highly purified plasma membranes separated from microsomal fractions of rat liver by density gradient centrifugation, the 57co-vitamin b12-rat tc-ii complex bound to high affinity sites on the vesicles via a specific (binding after correction for 'non-specific' bind ...19751201244
pure red cell aplasia: studies on an igg serum inhibitor neutralizing erythropoietin.a new type of igg serum inhibitor in adult pure red cell aplasia (prca) has been investigated. this inhibitor is directed against circulating erythropoietin (ep) (prca type b), rather than the erythroid marrow (prca type a). thus, the igg inhibitor, after interaction with ep in solution, is precipitated together with ep by addition of goat anti-human gamma-globulins. pre-therapy prca serum, although apparently devoid of ep, shows considerable ep activity following acidification and boiling. the ...19751201224
the oxygen affinity of haemoglobin hammersmith.oxygen dissociation studies were carried out on red cells and lysates from a patient heterozygous for hb hammersmith. the oxygen affinity of the cells at ph 7.1 was decreased, partly by an increased cellular concentration of 2,3-dpg and more importantly by an intrinsic low affinity of hb hammersmity. haem-haem interactions were reduced and an abnormal bohr effect (ph 7.1-7.4) was found in the cells which would bring about an additional decrease in oxygen affinity at physiological ph. oxygen diss ...20051201210
an improved method of assessing topical corticosteroid activity.topical application of ointment bases causes varying degrees of epidermal thickening in guinea-pigs. this is reproducible and can be accurately measured. suppression of these changes was produced by addition of beta-methasone 17-valerate, fluocinolone acetonide, fluocinonide and hydrocortisone acetate. the inhibitory effect of these steroids was related to the type of corticosteriod, its concentration and the ointment base. the effect was still evident at extremely high dilutions of the steroids ...19751201192
dermo--epidermal adhesion and its effect on epidermal structure in the mouse.evidence is presented that dermo--epidermal adhesion is low in mouse ear. consequently the pressure caused by mitotic activity in the basal epidermal layer is readily relieved by cell extrusion distally and the number of basal cells per unit skin area remains low. the rule then is that the number of distal cells per unit skin area must be equally low, and the epidermis is therefore thin. conversely, dermo--epidermal adhesion is high in mouse sole-of-foot epidermis, and the mitotic pressure leads ...19751201191
treatment of advanced bronchogenic carcinoma with adriamycin and 5-fluorouracil.thirty patients with an advanced bronchogenic carcinoma were treated with a combination of adriamycin and 5-fluorouracil; in eight the size of the tumour or its metastases was reduced by over 50%, and eight further patients experienced useful relief of symptoms. this drug combination is useful in the magagement of lung cancer.20051201186
location and the primary structure around the disulfide bonds in cholera toxin. 19751201095
isolation of single cell nuclei from human epidermis for cytophotometric dna--measurements.diluted acetic acid was applied to dissociate human epidermis into its constituents. a simple procedure to gain isolated single cells for cytophometric determination of their nuclear dna content is described. the method is suited for single cell cytophotometric measurements and for cytofluorimetric flow systems likewise. the losses of feulgen--stainable nuclear dna during preparation were studied in dependence on the incubation time of the cells in acetic acid. the kinetics of extraction of nucl ...19751200706
proceedings: wilson-mikity syndrome. 20051200695
changes in plasma nephelometry after oral fat loading in children with normal and abnormal small intestinal morphology.a standardized oral fat load has been given to 66 children having duodenal or jejunal biopsy, and to 10 children presumed normal. the rise in plasma light scattering intensity (lsi) measured by nephelometry between the fasting and 2-hour postload level (0-2 hour) showed good correlation with the small intestinal morphology in patients suspected of having coeliac disease. in those who had had recurrent diarrhoea and gastroenteritis, the fat load test did not predict small intestinal morphology. s ...20041200679
[surgical treatment of pulmonary embolism in obstetrical-gynecological practice]. 20051200312
[serotonin in complex treatment of uterine and ovarian neoplasms]. 20051200305
[changes in the lungs of white mice under the action of cholera exotoxin]. 19751199577
[influence of qualitatively different diets on the reproductive capacity and function of the adrenal cortex in rats with experimental toxic hepatitis].the effect of a diet rich in protein and the group b vitamins on the function of the ovaries and adrenal cortex, as well as on the reproductive capacity of animals with experimental affection of the liver produced by administration of carbon tetrachloride was studied on 115 mongrel albino female-rats. a high-standard semisynthetic diet devised at the institute of nutrition of the ams of the ussr and three isocaloric experimental diets calorifically enriched by 20, 50 and 100 per cent and contain ...19751199012
movement aftereffects contingent on the colour or pattern of a stationary surround. 20051198934
[the role of pylorus in gastric surgery (author's transl)]. 20051197807
immunotherapy with neuraminidase-treated tumor cells after radiotherapy. 19751197655
pharmacological investigations on elaeocarpus ganitrus. 19751197422
phloroglucinol derivatives of eleven dryopteris species from japan. 20051197418
editorial: to serve all the people. 20051196171
microchemical investigation of medicinal plants. xi. identification of morphine and codeine in opium using gc/ms. 20051196153
low hyperbaric therapy in management of leg ulcers. 20051196150
a volumetric assessment of pollen levels in the air of ann arbor, michigan. 20051196148
training for tomorrow's medicine. 20051196146
synchronization of the fission yeast schizosaccharomyces pombe using heat shocks. 19751196141
[on the quantification of statistic differences in epidemiology caused by selection (author's transl)]. 20051196140
[morphology of the hemolytic-uremic syndrome]. 20051196095
[pathology of arthrosis]. 20051196092
[treatment of ulcers and necrosis]. 20051196078
finger joint replacement with silastic implant. 20051196070
what's your diagnosis? 20051196062
method for double-contrast study of the colon. 20051196057
[realization of a plan for radiation teletherapy]. 20051196049
[medical radioisotope scintigraphy (physico-technical methods and means of collection of information)]. 20051196037
biochemical aspects of the adaptation of hemoglobin-oxygen affinity of eels to hypoxia. 20051196014
comparative in vivo distribution of opiate agonists and antagonists by means of double isotope techniques. 19751196002
laryngeal structure following microcauterization.the paper supports and reaffirms the objectives of contemporary laryngology in the treatment of cancer of this organ. these objectives are, first and foremost, the eradication of the tumor, and second, the preservation of function. a relatively recent contribution to the "state of the art" has been the development of the field of microlaryngology. the introduction of the surgical microscope has provided the laryngologist with better means to judge the type, localization and extent of neoplastic ...19751195967
malignant teratoma arising within a lipomeningocele. case report.the authors report the case of an 11-year-old, neurologically normal girl, followed since birth for lipomeningocele, who developed a malignant teratoma within the lymbosacral lesion and presented with metastases to the lungs and groin. this rare occurrence is discussed from an embryological and management viewpoint.20051194945
selective inhibition of cholera toxin- and catecholamine-stimulated lipolysis by blocking agents.vibrio cholerae enterotoxin stimulates lipolysis in rat epididymal fat cell suspensions. like hormones this toxin increases adenylate cyclase activity, raising levels of cyclic adenosine 3',5'-monophosphate (camp), which activates a cellular lipase. using specific blocking agents, we studied the responses to the adrenergic lipolytic hormones epinephrine, norepinephrine, and isoproterenol, and to cholera toxin. all stimulators were used at 100 x threshold dose. propranolol (34 mum), a beta blocki ...19751193734
a concise parametric representation of electrocardiograms. 20051193621
pharmacodynamic action of antygen vi. 19751191811
microbiological examination of ship sewage for the presence of vibrio cholerae. 19751191809
[effect of chronic irradiation in low doses on age-related changes in the radiation-resistance of white mice]. 20051188055
effects of cholera toxin on adenylate cyclase. studies with guanylylimidodiphosphate.similarities exist between the properties of adenylate cyclase after stimulation by cholera toxin and after stimulation by guanylylimidodiphosphate (gpp-(nh)p). thus a strong stimulation is achieved by both agents, the stimulation is essentially irreversible, the action of certain hormones is enhanced and the enzyme can be solublized with lubrol px in the activated state. because of these similarities the interaction of cholera toxin and gpp(nh)p on adenylate cyclase was examined. it was found t ...19751184756
metabolism of [5-t]fructose by isolated liver cells.glucose formed from [5-t]fructose in rat hepatocytes contains about 10 to 30% tritium. this does not appear to be due to fructose metabolism via hexokinase since neither the initial presence of glucose, nor wide variations in the original fructose concentration, have much effect on the relative labeling of glucose versus water from [5-t]fructose. comparison of the t:14c ratios in glucose produced from [u-14c, 5-t]fructose and d-[u-14c, 2-t]glyceraldehyde indicate that there is tritium retention ...19751184583
viability of vibrio cholerae biotype el tor and of cholera phage on vegetables.different vegetables were contaminated with sewage water containing large amounts of el tor vibrios, and the viability of these vibrios was studied under defined conditions of storage. during the dry season (summer) in jerusalem, the el tor vibrios survived for up to 24 hr on parsley, 24 to 30 hr on tomatoes and carrots, 24 to 48 hr on cucumbers, peppers and okra and two to three days on lettuce, when the vegetables were stored at room temperature. the survival time was longer during the rainy s ...19751184361
the organized distribution of acrosomal proteinase within the acrosomes of rabbit spermatozoa.acrosomal proteinase was found to be present in a highly organized distribution in the acrosomes of rabbit spermatozoa, using cytochemistry. this distribution consists of at least six linear loops of evenly spaced proteinase granules, which run diagonally across the flat side of the sperm head in a criss-crossing pattern. two additional loops may be present, one encircling the tip of the spermatozoon in the region of the acrosome reaction, and the other at the posterior end of the acrosome. the ...19751183631
sinoatrial block during lithium treatment.lithium is known to produce t wave changes in the ecg, whereas effect upon the conducting system of the heart has not been described. in our patient lithium produced sinoauricular block and possibly tachycardia. the correlation between lithium treatment and tachyarrhythmias is discussed. when during lithium treatment block is found, the treatment should preferably be stopped, but if this is not possible it is important to realize that digitalis should not be used as a prophylactic drug against t ...20051183468
[direct surgical revascularization in the therapy of angina pectoris. indications and choice of patients]. 20051183349
[mild course of botulinus intoxication (author's transl)].botulinus poisoning generally ends fatally after an only short course, mild forms being rare. in four members of a family who had eaten deep-frozen grilled sausages symptoms of botulinus poisoning developed, predominantly marked by disturbances of the autonomic nervous system. the course was so mild that hospitalization was not necessary nor was specific antitoxin administration. all clinical symptoms had disappeared after nine weeks. but special clinical and neurophysiological studies (electrom ...20051183348
[letter: adverse effects of antiepileptic drugs]. 20051183340
how long should patients keep off alcohol after infectious hepatitis? 20051183319
the forgotten treatment modality in bipolar illness: psychotherapy.the author presents 31 bipolar patients treated with combined lithium prophylaxis and psychotherapy for up to 41 months. the grave prognosis of untreated bipolar illness is reviewed. the improved prognosis with lithium prophylaxis alone is reviewed. the author demonstrates an improved prognosis when lithium prophylaxis is combined with psychotherapy and discusses his findings as to why lithium prophylaxis alone still predicts a grave outcome.20051183307
[early rehabilitation following total hip replacement]. 20051183289
xeromammography at a community hospital. a year's experience. 20051183210
cholera toxin effects on cell growth accompanied by selective alterations in metabolite uptake and modification of cell surface proteins.exposure of chinese hamster ovary cells to cholera toxin at or below mug levels causes a marked morphological changes and increased adhesion and orientation of the cells. such changes are paralleled by alterations in surface proteins as indicated by the cholera toxin-mediated modifications detectable by lactoperoxidase-catalyzed radioiodination of outer proteins. mild tryptic treatment of cells prelabeled with [3h]glucosamine revealed a different kinetics of release of external glycoproteins in ...19751182696
neuropsychological deficits in 'primary' and 'secondary' non-medical drug users.an extensive neuropsychological test battery, specifically designed to investigate brain-behaviour relationships, was administered to two groups of multiple drug users. the 'primary' group consisted of subjects referred fundamentally on account of drug abuse problems. the 'secondary' group were referred principally for neurological reasons, but during history taking they reported drug use. fifty patients, in all, were examined. results showed that people who have received psychiatric care for dr ...20051182648
letter: si units or sd units or both? 20051182619
kinetic amplification of enzyme discrimination.the dependence of the accuracy of enzymatic systems on the mechanism of the catalyzed reaction is investigated, using a probabilistic approach. certain mechanisms of reaction, involving a delay in one of the steps act as kinetic amplifiers of molecular discriminations. the relationship between our scheme for a delayed reaction [1] and hopfield's scheme [i] is discussed.20051182215
metabolic actions of vasopressin, glucagon and adrenalin in the intact rat.metabolic effects of vasopressin, glucagan and adrenalin were compared, in intact rats, especially in regard to time courses of effects. hyperglycaemia was transient in response to vasopressin, prolonged following adrenalin, and, suprisingly, was not discernible after glucagon, except in response to a very large dose. vasopressin decreased and adrenalin increased, the plasma free fatty acid concentration; both hormones decreased the triacylglycerol level. muscle glycogen concentrations, measured ...19751182200
a syndrome of acute zinc loss. cerebellar dysfunction, mental changes, anorexia, and taste and smell dysfunction.oral administration of the amino acid histidine to six patients with progressive systemic sclerosis produced anorexia, taste ans smell dysfunction, changes in mentation, and cerebellar dysfunction in each patient; these changes were associated with significant decreases in serum zinc concentration and significant increases in urinary zinc excretion. administration of zinc ion, even with continued histidine administration, returned each of the signs and symptoms to or toward normal within 8 to 24 ...20051180744
scope of ophthalmic plastic and reconstructive surgery. 20051177928
comparison of the aamd heber and grossman manuals on terminology and classification in mental retardation. 19731177751
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