Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| contamination of metronidazole discs with penicillin. | 1979 | 104759 | |
| [a rapid test for confirmation of "n. gonorrhoeae" (author's transl)]. | 1978 | 104667 | |
| [phagocytosis in urethral discharge before and during treatment of acute gonorrhea with methacycline]. | 1978 | 104468 | |
| [determination of colony types in gonococci]. | 1978 | 104458 | |
| chlamydia trachomatis cervicitis in gynecologic outpatients. | symptoms suggestive of a lower genital tract infection (lgti) are common complaints in women who consult gynecologists. sexually transmitted microorganisms, such as chlamydia trachomatis. neisseria gonorrhoeae, and trichomonas vaginalis, are responsible for a substantial proportion of lgti. this study was performed to establish the frequency of lgti caused by c trachomatis in women attending a gynecologic outpatient clinic. of 170 women with lgti, 32.9% harbored one or more of these organisms: c ... | 1978 | 104212 |
| meningitis caused by neisseria meningitidis serogroup 135. | the first descriptions of meningitis in childhood caused by neisseria meningitidis serogroup 135 are presented. difficulties with identification of unusual serogroups of n. meningitidis are discussed. | 1978 | 103892 |
| plaque assay for measuring serum bactericidal activity against gonococci. | a new semiquantitative plaque assay was developed to measure killing of gonococci by serum. results compare well with an established quantitative method, but the plaque assay is faster, simpler, and less expensive. | 1978 | 103891 |
| [beta-lactamase producing gonococci in munich (author's transl)]. | two more penicillinase-producing gonococci strains have been isolated in munich. the source of infection could not be traced in a 20 year old prostitute. a 45 year old patient contracted the infection during a stay in bangkok. | 1978 | 103843 |
| gonococcal color and opacity variants: virulence for chicken embryos. | previous studies have noted that the prevalence of certain gonococcal colony types is influenced by the physiological state of the human host. consequently eight different gonococcal strains were passed on clear typing medium, and opaque (op) and transparent (tr) variants of heavily pilated (p++) bacteria were selected. p++op and p++tr were injected into 11-day-old chicken embryos, and the resulting mortality was determined. in every case the tr variants were more lethal to the embryos than were ... | 1978 | 103830 |
| studies on gonococcus infection. xvi. purification of neisseria gonorrhoeae immunoglobulin a1 protease. | a protease which cleaves human immunoglobulin a1 (iga1) has been purified from broth cultures of neisseria gonorrhoeae. this iga1 protease is produced by pilated and nonpilated gonococci throughout their growth cycles. a combination of ammonium sulfate precipitation, column chromatography, and either isoelectric focusing or affinity chromatography was utilized to obtain an enzyme preparation that showed approximately 3,800-fold purification and exhibited two bands (65,000 and 70,000 daltons) by ... | 1978 | 103829 |
| inhibition of beta-lactamase in neisseria gonorrhoeae by sodium clavulanate. | sodium clavulanate at subinhibitory concentrations affected the activity of penicillin g, ampicillin, or amoxicillin on beta-lactamase-positive strains of neisseria gonorrhoeae as demonstrated by marked reduction in the minimal inhibitory concentrations of the drugs for the organisms. the compound did not affect the activity of these penicillins on beta-lactamase-negative strains of n. gonorrhoeae. it also had no effect on the activity of cefoxitin against either beta-lactamase-negative or -posi ... | 1978 | 103496 |
| effects of thiamphenicol and chloramphenicol in inhibiting neisseria gonorrhoeae isolates. | thiamphenicol was compared with penicillin, tetracycline, and chloramphenicol for its ability to inhibit 530 isolates of neisseria gonorrhoeae, including 13 penicillinase-producing isolates. thiamphenicol proved to be as active as chloramphenicol in inhibiting all of the isolates. | 1978 | 103495 |
| laboratory identification of pathogenic neisseria with special regard to atypical strains: an evaluation of sugar degradation, immunofluorescence and co-agglutination tests. | sugar degradation tests (sdt) were compared with immunofluorescence (ifl) and co-agglutination (coa) tests for the diagnosis of neisseria gonorrhoeae (gc) and neisseria meningitidis (mc). somewhat more than 5% of the gc strains and 8% of the mc strains were misinterpreted by sdt. on most occasions the disagreement between sdt and serological tests was due to the inability of the mc strains (less so for gc strains) to degrade sugars correctly. because of this, three out of 15 strains (20%) from p ... | 1978 | 103365 |
| [participation of bacterial neuraminidases in the development of disease]. | 1978 | 103344 | |
| [model of meningococcal sepsis in mice]. | the authors studied a possibility of obtaining experimental meningococcus sepsis model on mice. the use of cyclophosphane, iron compounds, yolk medium produced no significant organism. when 4--5% mucine was injected intraperitoneally together with meningococcus culture mice died with sepsis phenomena. differences were revealed in the sensitivity of linear and mongrel mice to meningococcus infection--akr mice proved to be more sensitive. at the same time it was found that mongrel mice weighing fr ... | 1978 | 103342 |
| laboratory-acquired gonococcal conjunctivitis. | 1979 | 102807 | |
| the surface properties of neisseria gonorrhoeae: topographical distribution of the outer membrane protein antigens. | gonococci were labelled with 125i using the lactoperoxidase system. the amount of label incorporated was similar with all strains including those which appeared capsulated. electrophoresis on sodium dodecyl sulphate-polyacrylamide gels revealed that the major proteins labelled were those found in outer membrane preparations. comparison of variants of one strain showed that the major outer membrane protein (protein i) was always present and heavily labelled. the second major protein (protein ii) ... | 1978 | 102733 |
| the surface properties of neisseria gonorrhoeae: determinants of susceptibility to antibody complement killing. | monovalent rabbit antisera were prepared to highly purified gonococcal lipopolysaccharide (lps), to pili and to two major purified outer envelope proteins. all these antisera were free from significant specific igm antibody and were standardized to 4 microgram specific igg antibody per test, permitting accurate comparisons between the different gonococcal surface antigens as triggers of the complement-dependent bactericidal reaction. lps was the most effective antigen at inducing a bactericidal ... | 1978 | 102732 |
| a simplified approach to cultures for gonorrhea. | 1978 | 102730 | |
| changing concepts of pelvic inflammatory disease. | 1978 | 102712 | |
| circulation of n. meningitidis in a child community. | 1978 | 102690 | |
| heat-modifiable outer membrane proteins of neisseria meningitidis and their organization within the membrane. | neisseria meningitidis group b serotype 2 strain m986 contains two predominant outer membrane proteins, with apparent molecular weights of 41,000 (protein b) and 28,000 (protein e). heating of outer membrane vesicles at 56 degrees c for 20 min caused much of b** to disaggregate and denature into b (41,000 daltons). in contrast, protein e could be rapidly solubilized by sds at room temperature into its monomeric state (e*), but it was not converted to its final higher apparent molecular weight of ... | 1978 | 102633 |
| [radioimmunologic determination of antimeningococcal antibodies: technic and vaccination results]. | 1978 | 102435 | |
| comparison of the in vitro activity of bay k 4999 and piperacillin, two new antipseudomonal broad-spectrum penicillins, with other beta-lactam drugs. | bay k 4999 and piperacillin, two new substituted ampicillins, were compared with other beta-lactam antibiotics, including carbenicillin, azlocillin, mezlocillin, benzylpenicillin, ampicillin, and cefoxitin, against a wide range of gram-positive and -negative organisms. bay k 4999 and piperacillin were extremely active against pseudomonas aeruginosa (50% inhibited by 2 mug/ml), being about 16-fold more active than carbenicillin. bay k 4999 was the most active drug against escherichia coli (50% in ... | 1978 | 102245 |
| meningococcal polysaccharide vaccines: recommendation of the public health service advisory committee on immunization practices. | meningococcal disease is endemic in the united states, and sulfonamide-sensitive serogroup b strains currently cause most cases. more than two thirds of all cases occur in persons less than 20 years old. three meningococcal polysaccharide vaccines are licensed for selective use in the united states: monovalent a, monovalent c, and bivalent a-c. this recommendation describes indications for their use, with particular attention to primary immunization, and use in pregnancy and in epidemic control. | 1978 | 102231 |
| meningococcal infection in egypt: laboratory findings in meningitis patients and the prevalence of pharyngeal infection in patients and contacts. | 1978 | 102212 | |
| evaluation of the microcult-gc kit as a screening method for the detection of neisseria gonorrhoeae. | the microcult-gc kit was compared to the standard modified thayer-martin plate method for the isolation and presumptive identification of neisseria gonorrhoeae. two hundred and thirty specimens representing urethral, endocervical, rectal, and pharyngeal sites were inoculated to both media. if only genital and rectal cultures were compared, the overall agreement was 98 percent, with a false positive rate of 1/145 (0.7 percent) and a false negative rate of 2/145 (1.4 percent). however, in the phar ... | 1978 | 102193 |
| liberation of endotoxin during growth of neisseria meningitidis in a chemically-defined medium. | modified medium 199 is well suited to the growth of meningococci if rich growth is not necessary. the bacteria were very sensitive to changes in ph and needed a good buffer capacity of the medium. four strains of neisseria meningitidis were studied. after the stationary phase had been reached, the vital cell count decreased relatively slowly. however, the total cell count remained unchanged for at least 12 hours. the standardized e. coli endotoxin could be detected easily by the limulus lysate t ... | 1978 | 102109 |
| [experimental contribution to the theme of pharyngeal gonorrhea]. | experimental inoculations of the pharynx with gonococci were undertaken. in seven volunteers gonococci could be cultivated and identified from 16 hours to 8 weeks following infection. in three cases, it was tried to infect the female genital tract using positive pharyngeal smears. this was successful in one instance and the diagnosis was again confirmed by culture and sugar fermentation. | 1978 | 102091 |
| acute joint infection with neisseria meningitidis: a case of mistaken identity. | 1978 | 101903 | |
| [unspecific prostato-urethritis. basis for the microbiological diagnosis]. | 1978 | 101830 | |
| [prostatitis inhibiting fertility. gonococci superseded by other microbes]. | 1978 | 101822 | |
| penicillinase-producing gonococci. | 1978 | 101754 | |
| penicillin resistance in neisseria gonorrhoeae due to beta-lactamase production. | two isolates of neisseria gonorrhoeae from two patients who did not respond to repeated treatment with penicillin were found to contain an active beta-lactamase. this enzyme has not been previously found in other gonococci isolated in the united states. compared to other gonococci, these isolates had higher penicillin minimal inhibitory concentrations, and gave very small or no zones of inhibition in the disc agar diffusion test. the enzyme was demonstrated with three different rapid tests for b ... | 1977 | 101741 |
| multiple antibiotic resistance in gonococci. | 1978 | 101637 | |
| [a case of bacterial endocarditis due to neisseria mucosa (author's transl)]. | 1978 | 101614 | |
| a simple manganous chloride and congo red disc method for differentiating neisseria gonorrhoeae from neisseria meningitidis. | manganous chloride and congo red incorporated into blotting paper discs have been used to differentiate gonococci from meningococci. the new technique is simple and reliable; the materials for the test are inexpensive. the method will increase the efficiency of distinguishing between the pathogenic neisseria in any clinical bacteriology laboratory and especially in those in the tropical areas. | 1978 | 101555 |
| cell envelope alterations in antibiotic-sensitive and-resistant strains of neisseria gonorrhoeae. | the cell envelopes of antibiotic-resistant and -sensitive isogenic strains of neisseria gonorrhoeae were analyzed to determine whether acquisition of genetic loci for altered antibiotic sensitivity was accompanied by alterations in cell envelope composition. no differences in the composition of phospholipids and lipopolysaccharides were noted. acquisition of mtr-2, which results in low-level, nonspecific increased resistance to multiple antibiotics, dyes, and detergents, was accompanied by a sev ... | 1978 | 101519 |
| iron in neisseria meningitidis: minimum requirements, effects of limitation, and characteristics of uptake. | a simple defined medium (neisseria defined medium) was devised that does not require iron extraction to produce iron-limited growth of neisseria meningitidis (sdic). comparison of this medium to mueller-hinton broth and agar showed nearly identical growth rates and yields. the defined medium was used in batch cultures to determine the disappearance of iron from the medium and its uptake by cells. to avoid a number of problems inherent in batch culture, continuous culture, in which iron and disso ... | 1978 | 101516 |
| arginine biosynthesis in neisseria gonorrhoeae: enzymes catalyzing the formation of ornithine and citrulline. | many of the neisseria gonorrhoeae strains isolated from patients require arginine for growth in a defined medium. as a basis for genetic studies of these arg- strains, we examined two biosynthetic enzymes of arg+ (nonrequiring) gonococci. cell-free extracts contained (i) glutamate acetyltransferase, which catalyzes the formation of l-ornithine from alpha-n-acetyl-l-ornithine, and (ii) ornithine transcaramylase, which catalyzes the reaction between l-ornithine and carbamyl phosphate, yielding l-c ... | 1978 | 101509 |
| the activity of three oral cephalosporins against neisseria gonorrhoeae. | 1978 | 101504 | |
| effects of iron and culture filtrates on killing of neisseria gonorrhoeae by normal human serum. | neisseria gonorrhoeae gc9, both colony types t2 and t4, were killed by normal human serum, although populations of colony type t4 were more susceptible. ferric ammonium citrate prevented the killing of populations of both t2 and t4 colony types. other iron compounds tested showed no protective effect, nor did ammonium citrate or the divalent cations magnesium or calcium. a filtrate from cultures of an n. gonorrhoeae strain grown in a liquid defined medium showed a similar protective effect in th ... | 1978 | 101468 |
| strain-dependent cytotoxic effects of endotoxin for mouse peritoneal macrophages. | the cytotoxic effects of bacterial lipopolysaccharides (lps) on mouse leukocytes have been examined in vivo and in vitro. intraperitoneal injection of lps into c57bl/6 mice greatly reduced the recovery of mononuclear cells; lps was cytotoxic for macrophages, but had a mitogenic effect on lymphocytes. similar effects of lps on peritoneal leukocytes were observed in vitro. when monolayers of adherent peritoneal cells were studied in vitro, cytotoxicity was also observed, suggesting that the effect ... | 1978 | 101460 |
| studies on gonococcus infection. xiv. cell wall protein differences among color/opacity colony variants of neisseria gonorrhoeae. | gonococci from colonies exhibiting optical opacity and dark coloration have surface proteins that are not visualized in isogenic transparent, light-colored colony forms. these "colony opacity-associated proteins" have apparent molecular weights varying from 24,000 to 30,000 by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate; their apparent molecular weights are independent of that for their major outer membrane protein. the opacity-associated proteins are more suscep ... | 1978 | 101459 |
| [experiences with a simple test system for the determination of beta-lactamase (penicillinase) in neisseria gonorrheae]. | 1978 | 101397 | |
| which neisseria? | 1978 | 101277 | |
| in-vitro antimicrobial susceptibility of neisseria gonorrhoeae in new zealand. | four hundred and forty-two isolates of neisseria gonorrhoeae were tested by an agar dilution method for their susceptibility to penicillin, ampicillin, tetracycline, cephaloridine, and spectinomycin. of these isolates, 295 were tested for their susceptibility to sulphamethoxazole and to trimethoprim by the same method, using oxoid diagnostic sensitivity test agar plus 7.5% laked horse blood instead of proteose no. 3 agar plus 1% isovitalex and 1% haemoglobin. one hundred (22.6%) of the isolates ... | 1978 | 101276 |
| in-vitro activity of antimicrobial agents against neisseria gonorrhoeae in brussels. | the minimum inhibitory concentrations (mics) of 18 antimicrobial agents against 104 strains of neisseria gonorrhoeae isolated in the brussels area between january and october 1976 have been measured. the mics for penicillin g, ampicillin, amoxycillin, carbenicillin, and cephalexin showed a bimodal distribution. the second modus strains of cephalexin (mic = 6.25 microgram/ml) were relatively resistant to penicillin g (mic greater than or equal to 0.08 microgram/ml). about 51% of all strains were ... | 1978 | 101275 |
| patient variables associated with penicillin resistance in neisseria gonorrhoeae. | in an ongoing cooperative study of uncomplicated genital gonorrhea within the united states, 6,735 pretreatment gonococcal isolates were tested for their in vitro resistance to penicillin. by using a regression analysis technique, we examined 99 patient-associated variables which might be associated with penicillin resistance of the isolates. patients were most likely to have relatively resistant isolates if they were black, had used antimicrobial agents within 2 weeks of treatment for gonorrhea ... | 1978 | 101129 |
| [about proteinic impurities checking in a meningococcal vaccine. mannitol interference in the lowry protein determination (author's transl)]. | 1978 | 101124 | |
| a comparison of genital infections caused by chlamydia trachomatis and by neisseria gonorrhoeae. | patients with culture-proven infections with neisseria gonorrhoeae or chlamydia trachomatis, or both, seen at the olmsted county health department sexually transmitted disease clinic were evaluated for the presence of dysuria and exudate. eighty-four patients (21%) had neither symptom. n. gonorrhoeae infection alone was most frequent (47%), but c. trachomatis predominated in men. dysuria was most often detected in men infected with c. trachomatis, but exudate was most frequently found in men inf ... | 1978 | 101076 |
| induction of dna synthesis in lymphocytes in vitro by various bacteria, with special reference to neisseria gonorrhoeae, in patients with uro-arthritis (reiter's disease). | antigen-induced lymphocyte proliferation was studied by quantitation of 14c-thymidine uptake in cell cultures. the induction of dna synthesis in vitro in lymphocytes from patients with uro-arthritis after stimulation by whole cells of virulent and avirulent n. gonorrhoeae, meningococci group b, and apathogenic neisseria (n. pharyngis) was compared with the dna synthesis in lymphocytes from healthy controls after stimulation with the same neisseria antigens. the difference between patients and th ... | 1978 | 100875 |
| therapy of gonorrhea. comparison of trimethoprim-sulfamethoxazole and ampicillin. | eighty-nine men with gonococcal urethritis were randomly treated with trimethoprim-sulfamethoxazole, four tablets (trimethoprin, 320 mg, and sulfamethoxazole, 1,600 mg) twice daily for two days, or ampicillin, 3.5 g, plus probenecid, 1 g, in a single dose. forty-one (95.3%) of 43 patients who received trimethoprin-sulfamethosazole and 41 (97.6%) of 42 given ampicillin were cured. neither drug caused major side effects. all isolates of neisseria gonorrhoeae were susceptible in vitro to trimethopr ... | 1978 | 100624 |
| familial deficiency of the seventh component of complement associated with recurrent bacteremic infections due to neisseria. | the serum of a 29-year old woman with a recent episode of disseminated gonococcal infection and a history of meningococcal meningitis and arthritis as a child was found to lack serum hemolytic complement activity. the seventh component of complement (c7) was not detected by functional or immunochemical assays, whereas other components were normal by hemolytic and immunochemical assessment. her fresh serum lacked complement-mediated bactericidal activity against neisseria gonorrhoeae, but the add ... | 1978 | 100562 |
| studies on the relationships between serum bactericidal activity and uncomplicated genital infections due to neisseria gonorrhoeae. | this report concerns the relationships between patients' uncomplicated genital infections due to neisseria gonorrhoeae and the bactericidal activity of their sera against their infecting organisms. forty isolates of n. gonorrhoeae and 91 serum samples were obtained from 23 patients with their first or repeated gonococcal infections. of 32 sera obtained at the time of infection, 14 (44%) were bactericidal for the infecting strains. of convalescent-phase sera from 27 infections, 12 (44%) were bact ... | 1978 | 100561 |
| identification of neisseria gonorrhoeae from primary cultures by a slide agglutination test. | hen antigonococcal lipopolysaccharide hen serum was used in a simple slide agglutination test for the identification of neisseria gonorrhoeae from primary isolates. | 1978 | 100511 |
| effect of a staphylococcin on neisseria gonorrhoeae. | phage group 2 staphylococcal strain ut0002 contains a large 56s virulence plasmid with genes that code for both exfoliative toxin and a specific staphylococcin termed bac r(1). four penicillinase-producing strains and three penicillin-susceptible strains of neisseria gonorrhoeae were killed by bac r(1). after 30 min of growth of the penicillin-resistant tr1 strain in 62.5 arbitrary units of bac r(1) per ml, loss of viability was approximately 90%, and, after 5 h, an approximately 99.99% loss of ... | 1978 | 100049 |
| [evaluation of the sanative action of rifampicin on the meningococcal carrier state]. | the results of the epidemiological control experiment on the efficacy of rifampicin in sanation of meningococci carriers are presented. the preliminary study of rifampicin sensitivity of 41 freshly isolated nasopharyngeal meningococcal strains showed that the mic of the drug for 63 per cent of the isolates was 0.04--0.1 gamma/ml. sanation was performed for 2 days; 1.2 g of the drug was used during the treatment course. the results of examination of 91 meningococci carriers showed that 4 days aft ... | 1978 | 100048 |
| cross-reactions between neisseria meningitidis and twenty-seven other bacterial species. | cross-reactions between antigens from n. meningitidis and antigens from 27 other bacterial species from clinical isolates representing 20 different genera were studied by quantitative immunoelectrophoretic methods. a water-soluble n. meningitidis antigen preparation and a corresponding pooled rabbit antiserum regularly presenting 48 immunoprecipitates were used as reference system. antigens from 16 other bacterial genera cross-reacted with one to four n. meningitidis antigens, whereas antigens f ... | 1978 | 99974 |
| beta-lactamase producing haemophili and neisseriae. | 1978 | 99937 | |
| [antagonistic and bacteriocinogenic activity of meningococci]. | antagonistic and bacteriocinogenic activity was studied in 169 strains of meningococci of various serological groups and with different localization in the human organism at the time of isolation. bacteriocinogenic activity was revealed in all the meningococcus strains (by delayed antagonism method), and, in addition, antagonistic activity was found in 100 strains. the inhibitory activity was the greatest in meningococci isolated from the cerebrospinal fluid. the data obtained suggest an importa ... | 1978 | 99921 |
| [fluorescent antibody technique in identification of neisseria gonorrhoeae-microcolonies grown on membrane filters (author's transl)]. | filter membranes (nucleopore, no. n060, cpr 01300, pore size 0.6 mu) are inoculated with a pure suspension of n. gonorrhoeae or a urethral smear from patients suffering from gonococcal urethritis. the membranes are placed on chocolate agar and incubated for three hours. after fixation in formaldehyd, grown microcolonies of n. gonorrhoea are detected microscopically after incubation of the membranes with a fluorescein-isothiocyanate labeled gonococcal antiserum (difco, charge no. 605907) (fig. 3- ... | 1978 | 99913 |
| [allergization of the body by neisseria meningitidis. i. the problem of the occurrence of n. meningitidis in cases of bronchial asthma of bacterial etiology (author's transl)]. | the object of the authors work was the examination of nasopharyngeal swabs on the prevalence of neisseria meningitidis. a group of 222 patients suffering from asthma bronchiale of bacteriological etiology was under observation in order to be able to prepare an autovaccine. nasopharyngeal swabs were inoculated on special nutrient media. neisseria meningitidis was found in 22%, mainly from nasopharyngeal swabs, together with haemophilus sp. and streptococcus pneumoniae. in 59% of examined cases th ... | 1978 | 99912 |
| [antibiotic concentration in the serum of women with gonorrhea administered benzylpenicillin and bicillin-3]. | 1978 | 99905 | |
| [methacycline in the therapy of gonorrhea in men]. | 1978 | 99904 | |
| [study of biological properties of lyophilized gonococcal strains for the purpose of their use for vaccine production. 1]. | 1978 | 99903 | |
| [electron-microscopic study of the effect of biseptol on the gonococcus in vitro and in vivo]. | 1978 | 99902 | |
| [types of gonococci]. | 1978 | 99901 | |
| [meningococcus carriers among university hospital personnel]. | 1977 | 99793 | |
| [local, natural or artificial immunity, and its importance in the protection against meningococcal disease]. | 1978 | 99792 | |
| iga protease production as a characteristic distinguishing pathogenic from harmless neisseriaceae. | iga proteases are extracellular enzymes of bacteria that have human immunoglobulin a of the iga1 subclass as their only known substrate. the identification of this enzyme in neisseria prompted us to determine whether iga protease production correlates with pathogenicity within this genus. multiple clinical isolates of neisseria gonorrhoeae, n. meningitidis and eight species of non-pathogenic neisseria that commonly colonize the normal human nasopharynx were examined for iga protease activity. al ... | 1978 | 99655 |
| sympathetic joint effusion in septic arthritis. | 1978 | 99527 | |
| piliation and colonial morphology among laboratory strains of meningococci. | colonial morphology and piliation were studied on twelve strains from various serogroups of neisseria meningitidis. six different colony types (m1 to m6) were identified. most strains elaborated only an m1 colonial type, which is similar to gonococcus t4. several combinations of piliation and colonial morphology were observed: (i) colonial variation in which neither parent nor variant were piliated; (ii) colonial variation involving piliated and nonpiliated cells; (iii) dissociation of piliated ... | 1978 | 99453 |
| outer membrane protein antigens in an enzyme-linked immunosorbent assay for salmonella enteric fever and meningococcal meningitis. | outer membrane protein preparations were obtained from strains of salmonella and neisseria meningitidis. solubilized cell envelope (ce) fractions from s. typhi and salmonella groups a, b, c, and e had very similar electrophoretic mobilities on polyacrylamide gel, and common antigens were demonstrated by immunodiffusion. ce appeared to be a more satisfactory antigen than the more purified preparation (t/tei) in the enzyme-linked immunosorbent assay (elisa) with sera from typhoid and paratyphoid p ... | 1978 | 99452 |
| a comparison of the in vitro activity of rosamicin, erythromycin, spiramycin, penicillin and tetracycline against n. gonorrhoeae, including beta-lactamase producing isolates. | 1978 | 99424 | |
| the susceptibility of neisseria gonorrhoeae to cefoxitin sodium. | 1978 | 99417 | |
| [bacteriological diagnosis of gonorrhea]. | 1978 | 99333 | |
| differences in susceptibilities of virulent strains and avirulent strains of neisseria gonorrhoeae to antimicrobial agents. | virulent cells (t1 colony type) and avirulent cells (t4 colony type) of neisseria gonorrhoeae were grown in a defined liquid medium in the presence of different antimicrobial agents. bacteria of t1 colony type were found to be more resistant than bacteria of t4 colony type to the inhibitory effects of specific concentrations of ampicillin (0.50 mug/ml) and penicillin (0.01 mug/ml). bacteria of t4 colony type, however, were found to be more resistant to the effects of chloramphenicol (0.40 mug/ml ... | 1978 | 99084 |
| [gonococcal sensitivity to penicillin in women with gonorrhea relapse and reinfection]. | penicillin sensitivity of gonococci isolated from patients with relapses and reinfection of gonorrhea was studied. the results of the study were compared with those of the sensitivity tests in primary patients. the gonococcal strains with decreased sensitivity to penicillin were isolated from 82 per cent of the gonorrhea relapses, 47.8 per cent of the patients with reinfection and 33.2 per cent of the primary patients. the average sensitivity of the gonococcal strains isolated from the patients ... | 1978 | 99082 |
| asymptomatic gonococcal urethritis in selected males. | 1978 | 99054 | |
| the activity of cephalosporins on beta-lactamase-producing neisseria gonorrhoeae. | the antibacterial activity of cephaloridine, cephalothin, cephalexin, cephradine, cefazolin, cefamandole, cefuroxime and cefoxitin was determined for six beta-lactamase-producing gonococci isolated in great britain and the usa. cefuroxime was most active against small and large inocula, then cefoxitin, while cephaloridine was least active. cefamandole was more active than cefazolin and cephalothin, but only on small inocula, and these three antibiotics, with the slightly inferior cephalexin and ... | 1978 | 98833 |
| microbiology of the vagina in children: normal and potentially pathogenic organisms. | vaginal cultures from 100 healthy girls, 2 months to 15 years of age, were examined for the presence of normal and potentially pathogenic microorganisms. corynebacterium vaginale, yeast species, and genital mycoplasmas were isolated from vaginal cultures from 13.5 %, 28%, and 28% of the girls examined, respectively. colonization with these organisms was not associated with signs or symptoms of vaginitis. neisseria gonorrhoeae was isolated from a 4-year-old with purulent vaginitis. trichomonas va ... | 1978 | 98750 |
| the bacterial pathogenesis of acute pelvic inflammatory disease. | to study the bacterial pathogenesis of acute pelvic inflammatory disease, peritoneal fluid was obtained by culdocentesis in 133 of 344 women with this disease. in 104 of the specimens bacteria were identified both in the gram-stained smear and culture. neisseria gonorrhoeae was isolated from the lower genital tract in over half of these women, and there were 3 patterns of bacterial recovery from peritoneal fluid: n gonorrhoeae alone (22%), n gonorrhoeae and other organisms (32%), and nongonococc ... | 1978 | 98745 |
| technique for transcervical intrauterine inoculation of the mouse. | suspensions of india ink or gonococci were inoculated into the murine uterus through the cervix with a simple plastic vaginal speculum and a 23 gauge blunted needle. the inoculated suspensions were distributed throughout both uterine horns, cervix, and vagina, but did not flow into the peritoneal cavity. this method avoided surgical stress as well as being simple, fast, and reproducible. | 1978 | 98665 |
| gonorrhea detection in posthysterectomy patients. | a retrospective study of women examined at the venereal disease clinic after hysterectomy was made to determine which culture site was most likely to show anogenital neisseria gonorrhoeae infection when the cervix was absent. seventeen of 104 such patients were culture positive for n gonorrhoeae. rates of positivity for our culture sites were as follows: urethral, 17/17 (100%); vaginal, 7/17 (41%); and rectal, 2/17 (12%). | 1978 | 98647 |
| perihepatitis associated with salpingitis in adolescents. | perihepatitis, one manifestation of complicated gonorrhea, is infrequently diagnosed and reported. this study was undertaken to examine the incidence of gonococcal perihepatitis in adolescents as well as to study the effect, if any, of this condition on tests of liver function. accordingly, the records of 137 adolescents with salpingitis were evaluated. right upper quadrant tenderness or hepatic enlargement was noted in 27, while amino transferase level elevations were observed in 19 of the 59 i ... | 1978 | 98646 |
| serum bactericidal action and activation of the classic and alternate complement pathways by neisseria gonorrhoeae. | in order to more fully understand the host defense mechanisms against gonococcal infections, we decided to define the role of the classic and alternate complement pathways in gonococcal ba. sera and infecting isolates were collected from several patients with genital and disseminated gonococcal infections. sera from two never-infected subjects and a hypogammaglobulinemic patient were also collected. sera from patients with genital gonorrhea and never-infected controls demonstrated marked ba for ... | 1978 | 98602 |
| phenotypic and epidemiologic correlates of auxotype in neisseria gonorrhoeae. | previous studies from seattle, wash., suggested that strains of neisseria gonorrhoeae which require arginine, hypoxanthine, and uracil (arg-hyx-ura- auxotype) are unifomly highly susceptible to penicillin g, are relatively resistant to complement-dependent killing by heated, pooled human serum, and are associated with disseminated gonococcal infection. for further study of the epidemiology of these strains and for analysis of the susceptibility to penicillin, serum sensitivity, and the nutrition ... | 1978 | 98600 |
| quantitative determination of the serum antibody response to the capsular polysaccharide of bacteroides fragilis subspecies fragilis in women with pelvic inflammatory disease. | the antibody response to the capsular polysaccharide of bacteroides fragilis subspecies fragilis in women with acute pelvic inflammatory disease was quantitated using a sensitive radioactive antigen-binding assay. antibody detected by this technique correlated highly with antibody measured by quantitative precipitin analysis (r = 0.99). paired acute- and convalescent-phase sera obtained from women from whom b. fragilis subspecies fragilis was isolated by culdocentesis showed significantly greate ... | 1978 | 98597 |
| bacteria induce lymphokine synthesis polyclonally in human b lymphocytes. | we have studied the ability of various bacteria to stimulate human lymphocytes to produce leukocyte migration inhibitory factor (lif). mononuclear cells from adult and cord blood as well as purified t and b lymphocytes were stimulated with killed bacteria. the culture supernatants were tested for the presence of lif by the agarose migration method. all nine bacterial strains tested activated unseparated mononuclear cells and b lymphocytes but not t cells to produce lif. lif was also present in c ... | 1978 | 98583 |
| sensitivity of gonococcus strains isolated in rotterdam to epicillin, ampicillin, penicillin and tetracycline. | quantitative determinations of the sensitivity to epicillin, ampicillin, penicillin and tetracycline were carried out for 67 gonococcus strains isolated from 67 males with urogenital gonorrhoea, and 38 strains isolated from 38 females with urogenital/rectal gonorrhoea. the results of the sensitivity determinations for ampicillin, penicillin and tetracycline were compared with the findings of a previous investigation. it was found that the gonococcus strains isolated from males had become slightl ... | 1978 | 98362 |
| [attempts at use of indirect hemagglutination in the diagnosis of gonorrhea]. | 1978 | 98361 | |
| factors for poor prognosis in fulminating meningococcemia. conclusions from observations of 67 childhood cases. | 1978 | 98253 | |
| [genera of penicillin-resistant neisseria gonorrhoeae]. | 1978 | 98236 | |
| [investigations of the incidence of neisseria gonorrhoeae on the pharyngeal mucosa (author's transl)]. | 1978 | 98235 | |
| effects of various divalent cations on the survival of neisseria gonorrhoeae in liquid media. | the effect of various concentrations of divalent cations on survival of gonococci in liquid medium was studied. the growth of neisseria gonorrhoeae was inhibited by manganous chloride in concentrations above 1 x 10(-5)mol/l while the growth of control organisms such as neisseria meningitidis and escherichia coli was not inhibited by the same salt even at 1 x 10(-2)mol/l. copper sulphate, cobaltous nitrate, nickel chloride, and zinc sulphate also had deleterious effects on gonococci. magnesium ch ... | 1978 | 98204 |
| genital inoculation of male macaca fascicularis with neisseria gonorrhoeae and ureaplasma urealyticum. | inoculation of the urethra, conjunctiva, pharynx, and anal canal of six male crab-eating macaques (macaca fascicularis) with urethral exudate from male patients with urethral gonorrhoea or with laboratory gonococcal strains was unsuccessful in establishing infection or producing increased polymorphonuclear leucocytes on gram stain. intraurethral inoculation with laboratory strains of ureaplasma urealyticum resulted in transiently positive urethral cultures for u. urealyticum and was associated i ... | 1978 | 98203 |
| [study of molecular heterogeneity and chemical nature of polymeric components of the meningococcus cell wall]. | the high-molecular fraction of substances of the cell wall of meningococci, groups a and b, isolated in free volume in gel filtration through sepharose 4b and containing both group and intergroup antigens proved to be consisting of 2 subfractions in gel-filtration through bio-gel a-150m. molecular weight of the first was within the range of 100--150 million dalton, and of the second--of 3 to 100 million dalton. in dissociation in sodium deoxycholate the high molecular fraction complex compound o ... | 1978 | 97883 |
| [personal prophylaxis of venereal diseases]. | 1978 | 97875 | |
| evaluation of spiramycin as a therapeutic agent for elimination of nasopharyngeal pathogens. possible use of spiramycin for middle ear infections and for gonococcal and meningococcal nasopharyngeal carriage. | varying doses of spiramycin were administered orally to healthy volunteers, and concentrations in serum and saliva were determined. the absorption of the drug was not significantly influenced by concomitant food intake. saliva peak concentrations were 1.3--4.8 times higher than peak concentrations in serum. the elimination half life was 2--3 h in serum, and 4--8 h in saliva. accumulation of the drug was seen in saliva but not in serum. the possible effect of spiramycin in eliminating bacteria fr ... | 1978 | 97775 |