Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| experimental visceral larva migrans in monkeys. i. clinical, hematological, biochemical and gross pathological observations on monkeys inoculated with embryonated eggs of the dog ascarid, toxocara canis. | 1976 | 827646 | |
| toxocariasis and ascariasis: a comparison. i. description of infection, haematological response, serum proteins and skin test with toxocara canis antigen. | 1976 | 823629 | |
| prevalence of sarcocystis infection and other intestinal parasitisms in dogs from a humane shelter in ohio. | fecal specimens from 500 stray dogs in columbus, oh, were examined for evidence of intestinal parasitisms. prevalences (%) of coccidia were: sarcocystis sp, 1.8; isospora canis, 1.8; and isospora ohioensis, 3.6. prevalences (%) of helminths were: toxocara canis, 19.2; toxascaris leonina, 10.2; trichuris sp, 42.2; capillaria sp; 1.0; ancylostoma sp, 60.8; uncinaria sp, 2.4; and taenia sp, 7.4. | 1976 | 815230 |
| [comparative study of the antigenic structure of toxocara canis (werner, 1782) and ascaris suum (goez, 1782) in immunodiffusion and immunoelectrophoretic reactions]. | 1975 | 809655 | |
| [galactogenic and prenatal toxocara canis infections in dogs (beagle). (brief communication)]. | 1976 | 786582 | |
| naturally infected dog droppings from public parks and playgrounds as a possible source of infections with salmonellae and helminths. | in two periods (spring/summer and autumn/winter) investigations for salmonellae and helminths were made with 300 naturally infected dog droppings each. in the first period 10.33% of the collected fecal samples had been infected with salmonellae of 10 different serovars. eggs of taxascaris leonina were found in 3.33%, eggs of toxocara canis in 4.33%, taeniid eggs in 1.67% and ancylostomatides in 3.33% of examined droppings. the investigations in the autumn/winter period showed 9% fecal samples in ... | 1978 | 756158 |
| [research on intestinal parasitic diseases in dogs of the city of rome]. | a survey on the diffusion of intestinal parasites of dogs in the town of rome. the results of a survey on the diffusion of cestodes and nematodes in a hundred dogs in rome are reported. the dogs were subjected to fecal examinations --- using both the flottation method and the mcmaster method -- and to the post-mortem examination of the intestine. at post-mortem examination 25 dogs were found parasitized by one or more species of nematodes, 19 by one or more species of cestodes and 12 both by ces ... | 1977 | 754133 |
| examination of soil for toxocara canis eggs in different governorates of egypt. | 1978 | 752711 | |
| investigation of intravital diagnosis of toxocara canis larva migrans in experimentally infected mice. | 1978 | 752406 | |
| [3 cases of inflammatory granuloma caused by toxocara canis]. | 1978 | 747875 | |
| patent toxocara canis infection in ascarid-naive dogs. | the effect of feeding different numbers of toxocara canis eggs on patent intestinal infections was studied in 45 ascarid-naive 62--64-day-old pups and 6 adult dogs. twenty-four of 25 pups fed 10 to 1,000 eggs developed patent intestinal infections, whereas none of the 20 pups fed 10,000 eggs developed patent intestinal infection. three of 6 presumably ascarid-naive dogs, 7, 10, and 52 months old fed 100 eggs each, developed intestinal infections. | 1978 | 739294 |
| gastrointestinal helminths in dogs from a humane shelter in indiana. | between january 1975 and august 1976, the alimentary tracts of 104 euthanatized dogs from a humane shelter in tippecanoe county, indiana, were examined to determine the prevalence of gastrointestinal helminths. the survey was restricted to dogs greater than 1 year old. their average age was estimated at approximately 2 years. parasitism was detected in 86.5% of the dogs examined. ancylostoma caninum was found most often (58.7%), followed by trichuris vulpis (51.9%), taenia sp (31.7%), toxocara c ... | 1978 | 721684 |
| parasites of red foxes in new brunswick and nova scotia. | sixty-one red foxes from new brunswick and nova scotia were examined for helminths. alaria americana, a. arisaemoides, a. mustelae, cryptocotyle lingua, echinostoma revolution and metorchis conjunctus, capillaria aerophila, crenosoma vulpis, toxocara canis, uncinaria stenocephala and taenia crassiceps were found. approximately 67% of the foxes examined were clinically affected with sarcoptes scabiei mange. | 1978 | 691132 |
| homologous passive cutaneous anaphylactic reactions to toxocara canis in mice. | 1978 | 675789 | |
| prevalence of toxocara spp. and other parasites in dogs and cats in halifax, nova scotia. | several cases of visceral larva migrans syndrome in children led to an investigation of the ova of toxocara spp. and other species in stool specimens from stray dogs and cats in halifax, nova scotia. fecal samples from 474 stray dogs and 299 stray cats were examined. ova of toxocara canis or cati were present in stools from 26.6% of the dogs and 25.1% of the cats. in dogs the prevalence of toxocara canis was noticeably greater in puppies (56.1%) than in mature animals (11.9%). | 1978 | 647456 |
| survey of toxocara canis infection rate in impounded dogs in los angeles county. | 1978 | 640937 | |
| anthelmintic efficacy of thenium closylate-piperazine phosphate combination tablets against toxocara canis in pups and young dogs. | thenium closylate-piperazine phosphate combination tablets, tablets containing either thenium or piperazine, and control tablets (excipients only) were administered in 2 doses 5 to 7.5 hours apart to weaned pups and young dogs, in critical controlled trials to test efficacy against naturally acquired infections of toxocara canis. in the 1st trial, the combination tablets produced a mean clearance of 94% from 18 pups. tablets containing thenium alone showed a mean clearance of 9% from 25 pups, an ... | 1978 | 629460 |
| incidence of toxocara canis infection in stray dogs in miraj area. | 1977 | 614252 | |
| a new approach to the control of toxocara canis and other parasitic ova on concrete-floored kennel runs. | 1977 | 608084 | |
| atypical ocular toxocariasis. | the case presented emphasizes that toxocara canis can involve the anterior segment of the eye as an isolated disease process. most cases of ocular toxocara canis are not associated with the other features of the visceral larva migrans syndrome but certainly represents a spectrum of the same parasitic disease. at present, an eosinophil count and isohemagglutinin titers against a and b blood groups appear the easiest hematologic studies to perform and are fairly reliable indicators of active toxoc ... | 1977 | 604441 |
| toxocariasis. | human infection with the larvae of the dog roundworm, toxocara canis, occurs in australia, especially in children, and though usually not serious, it can cause considerable damage if the larvae get into such organs as the eye. | 1977 | 603447 |
| gastro-intestinal helminths of domestic dogs in the republic of south africa. | of the gastro-intestinal helminths found in 1 063 dogs from different parts of the country, dipylidium caninum, the most prevalent cestode, occurred in 19,7% of the animals. echinococcus granulosus was present in 10 dogs, 8 of which were from urban areas, and taenia hydatigena in 69 dogs. taemia multiceps was recovered from dogs only in the cape province and the orange free state. toxocara canis was present in 81 of the necropsies carried out on 253 dogs from the pretoria municipal area, while a ... | 1979 | 575920 |
| toxocara infection in animal hospital employees. | the recent development of a sensitive and specific test (enzyme-linked immunosorbent assay) for toxocara canis infection has made it possible to study the epidemiology of this parasite in man. antibody to toxocara was measured in veterinarians, kennel workers, nurses, laboratory technicians, and clerical personnel in an animal hospital (animal medical center, new york, ny) in order to determine the risk of infection in persons with varying degrees of occupational and home exposure to pet dogs. a ... | 1977 | 563680 |
| spontaneous lesions detected in the beagles used in toxicity studies. | four hundred and twenty beagles 1 to 4 years of age were examined for spontaneous pathological changes. in the liver were seen fine granular gallstones (87.5%), granulomas (59.9%), intranuclear hyaline inclusions (52.6%), lipofuscin deposition (50%) and eosinophilic inclusions (3.7%) in the cytoplasm of hepatocytes and parenchymal necrosis at the base of the ligaments (7.3%). intranuclear hyaline inclusions and lipofuscin deposition were more frequently seen in dogs after being subjected to test ... | 1977 | 560313 |
| artificial hatching and culture of toxocara canis second stage larvae. | 1979 | 541764 | |
| use of fenbendazole suspension (10%) against experimental infections of toxocara canis and ancylostoma caninum in beagle pups. | eleven nematode-free beagle pups were inoculated with ancylostoma caninum and toxocara canis; infection became patent 13 and 35 days later, respectively. eight pups were treated with fenbendazole oral suspension (10%) at a dosage of 50 mg/kg of body weight/day for 3 days. the remaining three animals were unmedicated controls. the drug was effective in reducing both ascarid and hookworm burdens, and there was marked improvement in the clinical condition of treated pups as compared with unmedicate ... | 1979 | 517828 |
| [pathomorphologic changes in chicks infected with toxocara canis]. | 1979 | 516398 | |
| immunopathology of toxocara canis and ascaris suum infections of the eye: the role of the eosinophil. | intravitreal infection of guinea pigs with second-stage larvae of toxocara canis and second- and fourth-stage larvae of ascaris suum induced intraocular ige antibodies and a dense eosinophil infiltration in the anterior chamber and throughout the uveal tract. the eosinophil infiltrate began within 1 day after infection and persisted for as long as 51 days. by day 12 after intravitreal infection, the injected ascarid larvae were surrounded by granulomas which consisted almost entirely of eosinoph ... | 1979 | 511459 |
| the action of benzimidazoles on the larval stage of toxocara canis in the mouse. | 1979 | 496464 | |
| effect of fenbendazole on toxocara canis larvae in tissues of infected dogs. | the effect of fenbendazole therapy was studied in six dogs fed 10,000 embryonated toxocara canis eggs. at 47 days after they were fed t canis, four dogs were given fenbendazole in two divided doses totaling 50 mg/kg of body weight each day for 14 days. two infected dogs were not given fenbendazole. all dogs were necropsied at the end of treatment and the foci were counted in the lungs; their skeletal muscles were digested in 1% trypsin for the recovery of larvae. the t canis larvae were not reco ... | 1979 | 475114 |
| epidemiological characteristics and clinical findings in patients with serologically proven toxocariasis. | the enzyme-linked immunosorbent assay (elisa) using toxocara canis larva-specific antigens was used to confirm a presumptive clinical diagnosis of visceral larva migrans in patients whose serum specimens were submitted to the center for disease control. the clinical and epidemiological characteristics of patients with diagnostic elisa titres (greater than or equal to log2 5) were compared with patients who had less or no detectable antibody. the typical patient with serologically confirmed toxoc ... | 1979 | 473320 |
| toxocara canis. | toxocara canis, commonly known as the dog ascrid, is a frequent parasite of the domestic dog. if the eggs of an adult worm are accidentally ingested by a human host, usually a child, a larval form of the worm develops that can survive for a limited period in various human tissues. the retina is one of these tissues and upon the death of this organism a granulomatous reaction occurs and a fibrotic mass is formed in the retina. this unusual ophthalmoscopic appearance is demonstrated by the present ... | 1979 | 458104 |
| a survey of gastro intestinal helminth parasites of stray dogs in zaria, nigeria. | a survey of helminth parasites in stray dogs was carried out in the zaria area. out of 180 dogs examined 65.6 per cent (118/180) were found positive for ancylostoma caninum, while toxocara canis and trichuris vulpis were detected in 41.1 per cent (74/180) and 13.9 per cent (25/180) respectively. other helminth parasites found taenia ovis 35 per cent (63/180) taenia hydatigena 67.8 per cent (122/180), echinococcus granulosus 0.006 per cent (1/180) and dipylidium caninum 97.8 per cent (176/180). | 1979 | 452351 |
| eosinophilic meningitis: a suspected case of angiostrongylosis found in shizuoka prefecture, honshu, japan. | a patient with eosinophilic meningitis in shizuoka prefecture, honshu, japan had nausea, vomiting and headache on admission; laboratory examinations revealed leukocytosis with eosinophilia. eight days later neck stiffness appeared. lumbar puncture showed an increase of the initial pressure in association with eosinophilic pleocytosis in the spinal fluid. the possibility of angiostrongylosis was considered because the patient had eaten raw slugs for 4 years as a remedy for lumbago. although the s ... | 1979 | 434313 |
| [human larva migrans visceralis infections with toxocara in the german federal republic. serological investigations (author's transl)]. | the microprecipitation test on second generation larvae of toxocara canis has proved to be highly specific for the diagnosis of human larva migrans visceralis infection caused by toxocara species. out of a total of 2864 samples examined from 1969 to 1976, 248 were found to be positive. besides a very frequently occurring eosinophilia eye affections, lung changes and involvement of the cns are prominent clinical symptoms. the investigations show that larva migrans visceralis infections also occur ... | 1977 | 412096 |
| the enzyme-linked immunosorbent assay and its application to parasitic infections. | the enzyme-linked immunosorbent assay (elisa) was used for the serodiagnosis of four parasitic infections. elisa was performed as a macromethod in polystyrene tubes and/or as a micromethod in polystyrene microplates. conventionally raised pigs were infected orally with different numbers of trichinealla spiralis larvae, and the pigs' sera were tested for antibody to t. spiralis. results were compared with those from sera of uninfected conventionally raised pigs. cynomolgus monkeys were infected o ... | 1977 | 409790 |
| immunodiagnosis of parasitic zoonoses: comparative efficacy of three immunofluorescence tests using antigens purified by affinity chromatography. | three immunofluorescent antibody assays were developed during this study: the direct (dfat) and indirect (ifat) fluorescent antibody tests using frozen worm sections, and the cyanogen bromide indirect fluorescent antibody test (cnbr-ifat) using helminth antigens purified by affinity chromatography bound on to commercially prepared cnbr-sepharose 4b beads. purified antigens used in the cnbr-ifat gave greater specificity and sensitivity than either the dfat or ifat. dirofilaria immitis, toxocara c ... | 1978 | 354114 |
| visceral larva migrans. a review and reassessment indicating two forms of clinical expression: visceral and ocular. | visceral larva migrans is a disease in which the larvae of animal parasites invade human tissues but do not complete their life cycles. the most frequent cause of this illness in children is the dog roundworm, toxocara canis. a review of the literature, as well as our clinical experience, indicates that there are two forms of clinical expression: one, visceral, and the other, ocular. in general the clinical and laboratory abnormalities (hepatomegaly, recurrent pneumonia, eosinophilia, and hyperg ... | 1978 | 350038 |
| toxocara infection in pigs. the use of indirect fluorescent antibody tests and an in vitro larval precipitate test for detecting specific antibodies. | an in vitro larval precipitate test using second-stage toxocara canis larvae and an indirect fluorescent antibody (ifa) test employing cuticles of t. canis larvae as antigen were evaluated using antisera produced in pigs experimentally infected with t. canis, t. cati, ascaris suum, toxascaris leonina and parascaris equorum. the former test was both specific and sensitive and is suggested as a reliable and simple method of detecting toxocara antibodies in pigs. the latter test was considered unsu ... | 1977 | 328560 |
| helminths of british dogs: toxocara canis--a veterinary perspective. | 1977 | 323572 | |
| anthelmintics. | this article describes the drugs used in helminthic infections and their therapeutic indications, mode of action, toxicity and other details of each of the recommended drugs, and discusses the nature and treatment of infection by helminths important in human medicine. infestation due to the roundworms enterobius vermicularis, ascaris lumbricoides and the hookworms, ancylostoma duodenale and necator americanus can all be treated effectively with pyrantel pamoate. for enterobius vermicularis, howe ... | 1977 | 319991 |
| the efficacy of amidantel, a new anthelmintic, on hookworms and ascarids in dogs. | amidantel is a new anthelmintic from a new chemical class with an interesting anthelmintic spectrum. in dogs amidantel is highly effective in a single oral dose of 25 mg/kg against both hookworm species, ancylostoma caninum and unicinaria stenocephala. in toxascaris leonina infected dogs a complete cure rate was achieved with a single oral dose of 50 mg/kg. similar results were obtained with 8 mg/kg administered three times per day. the most sensitive parasite to amidantel was found to be toxoca ... | 1979 | 295548 |
| anthelmintic efficacy of pyrantel pamoate against the roundworm, toxocara canis, and the hookworm, ancylostoma caninum, in dogs. | 1978 | 250990 | |
| [simple method for obtaining toxocara canis antigen for the indirect immunofluorescence technic]. | a simple method for the preparation of toxocara canis antigen for the indirect immunofluorescent test is described: embryonated toxocara eggs are treated for 12 hours at room temperature with a 1:1 mixture of 2% naho and sodium hypochlorite (naclo) solution with a concentration of 2% free chlorine in order to remove the outer layers of the egg shells. the larvae which are still enclosed in the lipid membrane are freed by mild ultrasonic treatment. thereafter, the suspension of larvae is washed a ... | 1975 | 239550 |
| dual infections of mice: visceral larva migrans and sublethal infection with japanese encephalitis virus. | experiments in 3 weeks old albino mice with toxocara canis and sublethal infection with je virus established a marked synergestic effect in dually infected mice. the results are discussed to indicate the possible role of visceral larva migrans in creating exploxive outbreaks of "acute encephalopathy syndrome" in individuals having simultaneous infection with a virus (es) which, alone, might produce only mild illness. the nature of the possible mechanisms involved yet remains to be understood. | 1975 | 167480 |
| [demonstration of antibodies during experimental toxocarosis using antigenic extract prepared from the adult parasit]. | the detection of antibodies in subjects with visceral larva migrans syndrome caused by toxocara canis is usually carried out with antigenic larvae, whose preparation presents some difficulties. results obtained using extracts prepared from adult parasites show that such antigens are quite suitable for the detection of antibodies present in visceral larva migrans syndrome. this phenomenon is easily understood when one considers that there are numerous antigenic points in common between the differ ... | 1976 | 134802 |
| serologic differentiation of adult toxocara and ascaris. | the antigenic analysis of toxocara canis a causative agent of visceral larva migrans and ascaris suum has been carried out. agar gel double diffusion techniques and its modifications were employed to determine whether or not crude antigens, obtained from the adult parasites: (a) contained components unique for each, (b) could be used to differentiate the parasites serologically. adult toxocara canis and ascanis suum antigens used in this study were found to contain several unique antigenic compo ... | 1979 | 121695 |
| an experimental approach to the study of intraocular toxocara canis. | an experimental study of nematode endophthalmitis due to t canis and review of the literature has been presented. six owl monkeys were infected either by nasogastric tube using embryonated t canis eggs or by carotid or intravitreal injection of second stage larvae. the clinical manifestations, especially ocular, were observed and various diagnostic tests performed. only minimal or no intraocular changes were seen after systemic infection but significant abnormalities such as retinal hemorrhages ... | 1979 | 120993 |
| evaluation of serodiagnostic tests for visceral larva migrans. | four serologic techniques for the diagnosis of visceral larva migrans caused by toxocara canis, namely indirect hemagglutination (iha), bentonite flocculation (bf), enzyme-linked immunosorbent assay (elisa), and double diffusion in agar (ouchterlony), were evaluated using sera sent to the center for disease control from patients with a presumptive diagnosis of visceral larva migrans (vlm). patients having 5-6 of the clinical or laboratory criteria for vlm were designated as cases while those wit ... | 1978 | 98065 |
| comparative evaluation of 7 helminth antigens in the enzyme-linked immunosorbent assay (e.l.i.s.a.). | 112 sera from europeans with parasitologically proven helminthiasis were tested in the enzyme-linked immunosorbent assay (e.l.i.s.a.) against 6 crude extracts of various helminths (2 of adult worms: dipetalonema viteae, fasciola hepatica; 3 of eggs: ascaris suum, toxocara canis, schistosoma mansoni; and of echinococcus granulosus scolices) and against bovine hydatid fluid. each serum was tested simultaneously at a fixed dilution of 1:160 against all antigens. extensive cross-reactions were obser ... | 1979 | 92420 |
| the specificity of nematode allergens in the diagnosis of human visceral larva migrans. | extracts of nematodes have been used as skin test antigens in the diagnosis of nematode infections for many years. ascaris lumbricoides and toxocara canis are two nematodes commonly involved in human parasitism, the latter being associated with the clinical condition of visceral larva migrans. in vitro and in vivo experiments reported in this paper confirm experimentally, as well as clinically, the existence of cross-reacting antigens between t. canis and ascaris spp., and probably between t. ca ... | 1976 | 65168 |
| experimentally induced canine toxocariasis: laboratory examinations and pathologic changes, with emphasis on the gastrointestinal tract. | eght dogs were orally superinfected for 1 month with 50,000 embryonated toxocara canis ova. results of laboratory examinations during inoculation and for 2 weeks postinoculation revealed moderate leukocytosis, marked absolute eosinophilia, hypoalbuminemia, increased concentrations of serum glutamic pyruvate transaminase, and in 2 dogs, precipitating humoral antibodies. other changes were moderate ascites, hepatomegaly, lymphadenopathy, and focal lesions (0.5 to 3.0 mm) in liver, lung, kidney, in ... | 1975 | 53022 |
| specificity and sensitivity of skin test reactions to extracts of toxocara canis and ascaris suum ii. homologous 48-hour passive cutaneous anaphylaxis tests with sera from infected guinea pigs. | the specificity and sensitivity of adult and larval somatic antigens and perienteric fluid of toxocara canis and ascaris suum were investigated by using a modified passive cutaneous anaphylaxis procedure in guinea pigs. pooled sera from animals infected with low doses (0.01, 0.1, or 1.0 egg/g) were most reactive with the homologous larval antigen preparation. however, the toxocara antisera were highly reactive with this antigen only, whereas the ascaris antisera reactions could not be interprete ... | 1975 | 50748 |
| drug inhibition of anaphylactic histamine release from peritoneal cells of rats infected with toxocara canis. | an experimental model for studying anaphylactic histamine release from rat peritoneal cells in vitro is described. rats were sensitized by feeding the infective eggs of ttoxocara canis, the antigen being prepared from the infective eggs. the characteristics of histamine release are comparable with those found for other anaphylactic systems. addition of 0.2% inactivated normal rat serum to the incubation media reduced the spontaneous histamine release from 11.5 +/- 1.9% to 3.1 +/- 1.6% (mean +/- ... | 1975 | 50289 |