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establishment of orientia tsutsugamushi lc-1 (rickettsiales: rickettsiaceae) infection in icr outbred mice (rodentia: muridae) by needle challenge.orientia tsutsugamushi is a pathogen transmitted by leptotrombidium that causes scrub typhus. to develop an infection mouse model, a mite-derived isolate of o. tsutsugamushi was established from a laboratory-maintained colony of leptotrombidium chiangraiensis (o. tsutsugamushi lc-1). this lc-1 isolate was initially presented to icr (cd-1) mice by feeding an infected lc chigger on the ear of a mouse. once the lc-1 was adapted to the icr mice, quantitative real-time polymerase chain reaction was u ...201424897859
larval chigger mites collected from small mammals in 3 provinces, korea.a total of 9,281 larval chigger mites were collected from small mammals captured at hwaseong-gun, gyeonggi-do (province) (2,754 mites from 30 small mammals), asan city, chungcheongnam-do (3,358 mites from 48 mammals), and jangseong-gun, jeollanam-do (3,169 for 62 mammals) from april-november 2009 in the republic of korea (= korea) and were identified to species. leptotrombidium pallidum was the predominant species in hwaseong (95.8%) and asan (61.2%), while leptotrombidium scutellare was the pre ...201424850971
[research on the area distribution and host selection of leptotrombidium scutellare in 19 counties of yunnan province].in order to investigate the area distribution and host selection of leptotrombidium scutellare in yunnan province, a field survey was carried out during 2001 to 2009, based on different geographic location, topography, climate and ecological characteristics. a total of 16 491 l. scutellare were captured from the body surface of 9 838 small mammal hosts of 7 families, 18 genera, and 30 species in 4 orders, accounted for 17.73% (16,491/92,990) of all chigger mites collected. l. scutellare distribu ...201124830206
[geographical distribution of chigger mites on rattus flavipectus in yunnan province].to investigate species composition of chigger mites on rattus flavipectus in different zoogeographical subregion of yunnan province.201324818399
[investigation of chigger mites on small mammals in a flatland area of menghan, xishuangbanna, yunnan province].to investigate the species composition and distribution of chigger mites on small mammals in flatland area in menghan, xishuangbanna of yunnan province.201324812883
a new species of chigger mite (acari: trombiculidae) from rodents in southwest china.this paper describes a new species of chigger mite (acari: trombiculidae), gahrliepia cangshanensis n. sp., from rodents in southwest china. the specimens were collected from yunnan red-backed voles, eothenomys miletus (thomas, 1914), and a chinese white-bellied rat, niviventer confucianus (milne-edwards, 1871) in yunnan province. the new species is unique mainly in its number of dorsal setae (n=21), and it has the following features: ft (formula of palpotarsus)=4b (b=branched), fp (formula of p ...201424623884
tungiasis in haiti: a case series of 383 patients.tungiasis is endemic in poverty-stricken communities of south and central america, africa, asia, and the caribbean. this ectoparasitosis, caused by the female sand flea tunga penetrans, is associated with considerable longterm morbidity in severely affected patients, including toe deformation and limited mobility. in haiti, tungiasis is poorly documented but is known to occur. this study is the first formal investigation of tungiasis in haiti.201424601858
neotrombicula inopinata (acari: trombiculidae) - a possible causative agent of trombiculiasis in europe.for over a decade, the presence of trombiculid mites in some mountain areas of la rioja (northern spain) and their association with seasonal human dermatitis have been recognized. this work aimed to establish the species identity of the agent causing trombiculiasis in the study area.201424589214
[tungiasis, an emerging tropical disease in chile: three imported cases reports].tungiasis is a cutaneous ectoparasitosis caused by the sand flea tunga penetrans whose higher prevalence occurs in south america, the caribbean and sub-saharan africa. it is clinically characterized by a papular lesion, either single or multiple, with a whitish halo and a brown-black central core, most of them localized on the feet. the lesions can be painful and itchy with the most common complication being bacterial superinfection of the skin. we report three cases of chilean patients who pres ...201324522316
molecular epidemiology of orientia tsutsugamushi in chiggers and ticks from domestic rodents in shandong, northern china.scrub typhus is endemic to a 13,000,000-km² area of the asia-pacific region, and causes an annual incidence of 1 million people. the mortality rate of scrub typhus ranges from 6.1% to 25% in southeast asia. natural infection of orientia tsutsugamushi has been identified in domestic rodents in shandong province. however, infestation of chiggers and ticks on the domestic rodents and prevalence and genotypes of o. tsutsugamushi in these acarina remain unclear.201324499627
a new genus and two new species of chigger mites (acari: trombiculidae) from the laotian rock-rat laonastes aenigmamus jenkins, kilpatrick, robinson & timmins (rodentia: diatomyidae).a new chigger mite genus laotrombicula n. g. and two new species, laotrombicula khunboromi n. sp. (type-species) and l. fangumi n. sp., are described from the laotian rock-rat laonastes aenigmamus jenkins, kilpatrick, robinson & timmins (rodentia: diatomyidae). the new genus is most similar to trombiculindus radford, 1948 and leptotrombidium nagayo, miyagawa, mitamura & imamura, 1916 and differs from these genera by having the scutum of subhexagonal or semicircular shape vs widely rectangular; p ...201424395573
arthropod bites.the phylum arthropoda includes arachnids and insects. although their bites typically cause only local reactions, some species are venomous or transmit disease. the two medically important spiders in the united states are widow spiders (latrodectus), the bite of which causes intense muscle spasms, and the brown recluse (loxosceles), which may cause skin necrosis. widow bites usually respond to narcotics, benzodiazepines, or, when necessary, antivenom. most recluse bites resolve uneventfully witho ...201324364549
field assessment of orientia tsutsugamushi infection in small mammals and its association with the occurrence of human scrub typhus in taiwan.we conducted an extensive study in taiwan of orientia tsutsugamushi (ot) infection in small wild mammals. field trapping was carried out at six districts in eastern and western taiwan as well as various offshore islands during the period 2006-2010. a total of 1061 specimens representing 11 rodent species were captured. the presence of ot infection was assessed by indirect immunofluorescence assay and polymerase chain reaction assays of 56-kda type-specific antigen gene. the chigger infestation r ...201424361181
infestation of tunga penetrans in villages near zomba central hospital.an outbreak of tunga penetrans (jigger flea) infestation affecting a number of villages near to a central hospital in malawi is described. due to the large number of affected individuals, high parasitic load, and extended duration of infection an alternative to the recommended approach of surgical removal of the flea was required. benzyl benzoate paint and liquid paraffin had been used in local primary healthcare settings previously and topical treatment with antiparasitic agents has been advoca ...201324358427
characterization based on the 56-kda type-specific antigen gene of orientia tsutsugamushi genotypes isolated from leptotrombidium mites and the rodent host post-infection.abstract. characterization of the 56-kda type-specific antigen (tsa) genes of orientia tsutsugamushi (ot) from three naturally infected, laboratory-reared mite colonies comprising three species (leptotrombidium deliense [ld], leptotrombidium imphalum [li], and leptotrombidium chiangraiensis [lc]) has revealed the presence of single and coexisting ot genotypes found in individual chiggers. the karp genotype was found in all of the chiggers examined, whereas gilliam and ut302 genotypes were only o ...201424297814
the fate of the embedded virgin sand flea tunga penetrans: hypothesis, self-experimentation and photographic sequence.we describe the morphological development of a single penetrated female sand flea (tunga penetrans) in a medical expatriate working in madagascar. the embedded parasite developed abnormally in two aspects. first, it lived twice as long as usually. second, it did not expel a single egg during a period of two months. we explain these abnormalities by the fact that the female sand flea remained virgin after the penetration into the skin and, therefore, mature eggs did not develop. our observations ...201324225219
tungiasis - a janus-faced parasitic skin disease.tungiasis is a parasitic skin disease caused by the penetration of female sand fleas (tunga penetrans). it is acquired when people walk barefoot or rest on soil, where sand fleas have completed the off-host cycle. tungiasis is a classic poverty-associated disease which belongs to the family of neglected tropical diseases (ntd). it has a janus-face: while in travellers tungiasis usually is a benign self-limiting skin disease, inhabitants of endemic areas suffer from heavy infestations and severe, ...201324211240
ectoparasite burdens of the common mole-rat (cryptomys hottentotus hottentotus) from the cape provinces of south africa.the members of the african mole-rat family bathyergidae are widely distributed across sub-saharan africa. despite their well-studied biology and reproductive physiology, the current knowledge of their ectoparasite fauna is limited and ambiguous due to recent revisions of the bathyergid taxonomy. the common mole-rat (cryptomys hottentotus hottentotus) is 1 of the most widely distributed species of these subterranean rodents. ectoparasites were collected from 268 common mole-rats at 2 localities ( ...201424171714
are there spatial and temporal correlations in the incidence distribution of scrub typhus in korea?a hierarchical generalized linear model (hglm) was applied to estimate the transmission pattern of scrub typhus from 2001 to 2011 in the republic of korea, based on spatial and temporal correlation.201324159528
prevention of tungiasis and tungiasis-associated morbidity using the plant-based repellent zanzarin: a randomized, controlled field study in rural madagascar.tungiasis, a parasitic skin disease caused by the female sand flea tunga penetrans, is a prevalent condition in impoverished communities in the tropics. in this setting, the ectoparasitosis is associated with important morbidity. it causes disfigurement and mutilation of the feet. feasible and effective treatment is not available. so far prevention is the only means to control tungiasis-associated morbidity.201324069481
tungiasis under dermoscopy: in vivo and ex vivo examination of the cutaneous infestation due to tunga penetrans.the female flea tunga penetrans is responsible for a cutaneous parasitosis known as tungiasis. we report the clinical case of a 12 year-old caucasian boy who sought treatment in a dermatological private office due to a painful lesion in the plantar area and whose dermoscopic examination, without skin contact, allowed the visualization of parasite's movement inside the skin. the diagnosis of tungiasis is clinical, but it can be aided by in vivo and ex vivo dermoscopic examination of the lesion.201524068146
regression of severe tungiasis-associated morbidity after prevention of re-infestation: a case series from rural madagascar.tungiasis (sand flea disease) is a neglected tropical disease. heavy infestation results in mutilation of the feet and difficulty in walking. we identified eight individuals with extremely severe tungiasis in rural madagascar. to prevent reinfestation, four individuals received solid shoes and four received a daily application of an herbal repellent effective against tunga penetrans. over a period of 10 weeks the feet were examined and the severity of tungiasis-associated morbidity was measured. ...201324043689
eschar in scrub typhus: a valuable clue to the diagnosis.scrub typhus is an acute febrile illness widely prevalent in the 'tsutsugamushi triangle' region of the world. clinical features include fever, myalgia, headache, rash, and a pathognomonic eschar. an eschar is formed by the bite of chigger mite that inoculates the causative agent of scrub typhus orientia tsutsugamushi. the aim of this study is to determine the most common sites of eschars over the bodies of patients with scrub typhus.201524029193
tungiasis: a neglected epidermal parasitic skin disease of marginalized populations--a call for global science and policy.tungiasis (sand flea disease) is an ectoparasitic skin disease caused by the female sand flea/jigger flea (tunga penetrans). as poverty is the major driving force of the disease, it can be called as a poverty-associated plague. it is one of the emerging neglected diseases in latin america, caribbean, sub-saharan africa, and india. the aim of the present scrutiny was to assess the public health impact of tungiasis, associated risk factors, and emerging opportunities to prevent and control tungias ...201323949241
demodectic mange, dermatophilosis, and other parasitic and bacterial dermatologic diseases in free-ranging white-tailed deer (odocoileus virginianus) in the united states from 1975 to 2012.the white-tailed deer (odocoileus virginianus) is a common and widespread north american game species. to evaluate the incidence, clinical manifestations, demography, and pathology of bacterial and parasitic dermatologic diseases in white-tailed deer in the southeastern united states, we retrospectively evaluated white-tailed deer cases submitted to the southeastern cooperative wildlife disease study from 1975 to 2012. among 2569 deer examined, bacterial or parasitic dermatologic disease was dia ...201323912715
ectoparasitic insects and mites on yunnan red-backed voles (eothenomys miletus) from a localized area in southwest china.ectoparasitic insects and mites on yunnan red-backed voles (eothenomys miletus) in dali prefecture, yunnan province, southwest china, were studied between 2003 and 2004. in total, 34,389 individuals of 86 species of ectoparasitic insects (seven species of fleas and five species of sucking lice) and mites (23 species of gamasid mites and 51 species of chigger mites) were collected from 916 individual hosts. the diversity of ectoparasites on this single rodent species in such a small area was much ...201323907632
repellency of cassia bark, eucalyptus, and star anise oils and their major constituents to leptotrombidium pallidum (acari: trombiculidae).leptotrombidium pallidum (nagoya, miyagawa, mitamura & tamiya) is a primary vector of orientia tsutsugamushi (hyashi), the causative agent of scrub typhus. an assessment is made of the repellency to l. pallidum larvae (chiggers) of cassia bark, eucalyptus, and star anise oils and major constituents (e)-cinnamaldehyde, 1,8-cineole, and (e)-anethole of the corresponding oils. results were compared with those of conventional repellents deet (n,n-diethyl-3-methylbenzamide), ir3535 [(ethyl 3-[acetyl( ...201323802452
establishment of tunga trimamillata (siphonaptera: tungidae) in brazil.tunga trimamillata is a species of sand flea occurring in ecuador and peru parasitizing cattle, goat, sheep, swine, and man. this is the first report of this species in brazil, having been found on the hooves of cows in barretos, são paulo state, and felixlândia, minas gerais state, and previously misidentified as tunga penetrans. a previous report concerning hydrochoerus hydrochaeris from rio novo, minas gerais state, may also be attributed to that species of sand flea, a possible the primary h ...201323797275
consistency of the key genotypes of orientia tsutsugamushi in scrub typhus patients, rodents, and chiggers from a new endemic focus of northern china.scrub typhus is one of the most common infectious diseases of rural south and southeastern asia and the western pacific. it emerged in shandong province in northern china from autumn to winter of 1986. since then, the "autumn-winter type scrub typhus" has been found in many areas of northern china. however, the principle genotypes of orientia tsutsugamushi still remain unknown. this study was undertaken to identify the genotypes of o. tsutsugamushi obtained from scrub typhus patients, chigger mi ...201323760611
[geographical distribution and host selection of leptotrombidium rubellum in some parts of yunnan province].to investigate the geographical distribution and host selection of leptotrombidium rubellum among different small mammal hosts in some areas of yunnan province, china.201323751471
scrub typhus outbreak, northern thailand, 2006-2007.during a scrub typhus outbreak investigation in thailand, 4 isolates of o. tsutsugamushi were obtained and established in culture. phylogenetic analysis based on the 56-kda type-specific antigen gene demonstrated that the isolates fell into 4 genetic clusters, 3 of which had been previously reported and 1 that represents a new genotype.201323647883
acarine ectoparasites of panti forest reserve in johore, malaysia.to identify the presence of acarine ectoparasites and determine whether there is any potential public health risk in panti forest reserve, johore, malaysia.023569714
histopathological features of tungiasis in peru.tungiasis is an ectoparasitic skin disease caused by tunga penetrans and tunga trimamillata. there is a lack of histopathological studies that evaluate the recognition of this flea in tissues. we describe the ex vivo dermoscopic and the histopathological patterns of six cases and relate the findings to the developmental stage of the parasite as defined by the fortaleza classification: two were classified as fortaleza 3b, 3 as 4a, and 1 as 4b. two dermoscopic patterns were observed: a brown pigme ...201323478579
severe ulceronecrotic dermatitis associated with mite infestation in the critically endangered amargosa vole (microtus californicus scirpensis).the entire range of the critically endangered amargosa vole (microtus californicus scirpensis) consists of less than 20 km(2) of riparian habitat in the amargosa river drainage of the mojave desert in southern california. in september 2010, deformities on ears and chiggers on the ears and genitalia were detected, with some individuals so severely affected that they were missing ear pinnae altogether. follow-up trapping was performed to document the presence of mites and mite-associated disease, ...201323458565
a survey of acarine ectoparasites of bats (chiroptera) in malaysia.a comprehensive 8-yr survey of acarine ectoparasites (ticks and mites) of bats was carried out in 18 localities from 2002 to 2009. most of the surveys were conducted during 14 national biodiversity scientific expeditions throughout malaysia. the objective was to identify acarines of known public health importance from bats and thus determine whether there is any potential public health risk in malaysia. trapping of bats was conducted using harp traps and mist nets. in total, 1,579 individuals co ...201323427663
[tungiasis in bangou (west cameroon)].tungiasis is an ectoparasitosis caused by penetration into the skin of the sand or chigger flea, tunga penetrans. the epidemiology in cameroon of this disease, often associated with poverty, is unknown. accordingly, in august 2008, we conducted a study in bangou, in western cameroon, among a sample of 403 people, divided in 111 families. all data were collected and analyzed with epi-info 6.4 software. the prevalence in this population was 32.7%, with infestation more frequent in males (p = 0.013 ...201623419286
[persistent pruritus caused by tropical chiggers. trip to brazil caused a phenomenon unknown in sweden]. 201323367551
smallholder pig production: prevalence and risk factors of ectoparasites.a cross-sectional study was carried out in the mbeya region, tanzania, with the aim of describing the distribution and diversity of ectoparasites on pigs, within confinement and free-range production systems of smallholder farms. a total of 128 farms were surveyed, with 96 practising confinement and 32 practising free-range production systems. the prevalence of ectoparasites on pigs within confinement and free-range production systems was 24% and 84%, respectively. logistic regression analyses r ...201323357599
monthly occurrence of vectors and reservoir rodents of scrub typhus in an endemic area of jeollanam-do, korea.monthly surveys were conducted to investigate the occurrence of chigger mites and seroprevalence of scrub typhus among small mammals in jeollanam-do, the southwestern part of korea, from november 2006 through october 2007. fifty-eight small mammals, including 57 apodemus agrarius (98.3%) and 1 crocidura lasiura (1.7%), were captured, and a total of 4,675 chigger mites representing 4 genera and 8 species were collected from them. the chigger infestation rate among small mammals was 69.0%. the mos ...201223230330
abundances and host relationships of chigger mites in yunnan province, china.this paper reports on ectoparasitic chigger mites found on small mammals in yunnan province, southwest china. data were accumulated from 19 investigation sites (counties) between 2001 and 2009. a total of 10 222 small mammal hosts were captured and identified; these represented 62 species, 34 genera and 11 families in five orders. from the body surfaces of these 10 222 hosts, a total of 92 990 chigger mites were collected and identified microscopically. these represented 224 species, 22 genera a ...201323167491
cascading effect of economic globalization on human risks of scrub typhus and tick-borne rickettsial diseases.the increase in global travel and trade has facilitated the dissemination of disease vectors. globalization can also indirectly affect vector-borne diseases through the liberalization of cross-border trade, which has far-reaching, worldwide effects on agricultural practices and may in turn influence vectors through the modification of the ecological landscape. while the cascading effect of economic globalization on vector-borne diseases, sometimes acting synergistically with regional agricultura ...201223092017
outbreak of tungiasis following a trip to ethiopia.tungiasis is a skin disease caused by the ectoparasite sand flea tunga penetrans. although tungiasis is an important health problem in endemic areas, mainly south america and sub-saharan africa, it is reported uncommonly in travelers. we describe an outbreak of tungiasis in a group of travelers to ethiopia. following the diagnosis of tungiasis in a member of a group of 17 israeli travelers to ethiopia, other affected members were identified by photograph assisted self diagnosis. the characterist ...201223031181
a revision of the chigger mite genus paratrombicula goff & whitaker, 1984 (acari: trombiculidae), with the description of two new species.the monotypic chigger mite genus paratrombicula goff & whitaker, 1984 is expanded to include five species. two new species of chiggers, parasitising iguanid lizards in chile, paratrombicula chilensis n. sp. and p. goffi n. sp., are described, and two species, p. neuquenensis (goff & gettinger, 1995) n. comb. and paratrombicula plaumanni (brennan & jones, 1964) n. comb., are transferred to this genus from parasecia loomis, 1966 and neotrombicula hirst, 1925, respectively. a key to the species of ...201222983798
host body microcosm and ectoparasite infracommunities: arthropod ectoparasites are not spatially segregated.we studied the distribution of ectoparasite species (an ixodid tick, a chigger mite, 7 mesostigmate mites, 5 fleas and 3 lice) on bodies of 5 species of rodent hosts from the marshlands in argentina to establish whether arthropod ectoparasites are segregated across body parts of the same host individual. we asked (a) whether an individual ectoparasite species prefers certain parts of the body of its host and, if yes, whether these preferences overlap among ectoparasite species; (b) whether ectop ...201222948069
tungiasis (sand flea disease): a parasitic disease with particular challenges for public health.tungiasis (sand flea disease) is caused by the penetration of females of tunga penetrans into the skin of the feet. within 2 weeks of penetration the burrowed flea increases its volume by a factor of 2,000. this is paralleled by intense inflammation of the surrounding tissue. acute and chronic inflammation leads to the development of painful and debilitating clinical pathology. this results in impaired physical fitness and mobility. the social implications of tungiasis-associated morbidity are m ...201322941398
efficacy of plant essential oils for the repellents against chiggers (leptotrombidium imphalum) vector of scrub typhus.scrub typhus caused by the orientia tsutsugamushi. rodents, particularly rats, serve as principal reservoir hosts. infection in man is transmitted by the, chigger bite. repellents provide an effective agent of protecting individuals from chigger. in the present study 6 plant essential oils were tested for evaluation of their repellent activity against the chigger, leptotrombidium imphalum. the results showed that clove oil was significantly more effective than others with ed50 and ec50 of 0.420 ...201222934454
high prevalence of intestinal infections and ectoparasites in dogs, minas gerais state (southeast brazil).in the present study, 155 dogs euthanized by the zoonotic disease unit of uberlândia in minas gerais state (southeast brazil) were autopsied. ectoparasites were collected, and the intestinal content of dogs was systematically examined for the presence of helminthic parasites. in total, we isolated 5,155 metazoan parasites of eight species (three intestinal helminth species, five ectoparasite species). the cestode dipylidium caninum was present in 57 dogs (36.8 %), the nematodes ancylostoma canin ...201222825284
tunga penetrans and further parasites in the giant anteater (myrmecophaga tridactyla) from minas gerais, brazil.the brazilian savannah-like area, the cerrado region, covers large areas of the country and provides a habitat for a multitude of different animal species. the giant anteater (myrmecophaga tridactyla) is geographically widespread and one of the typical inhabitants of the cerrado. they are listed as vulnerable by the international union for conservation of nature and natural resources. a population loss of at least 30 % over the past 10 years has been estimated based on local extinctions, habitat ...201222814770
trombiculiasis caused by chigger mites eutrombicula (acari: trombiculidae) in peruvian alpacas.trombiculiasis is an infestation caused by larvae members of the family trombiculidae, common called chigger mites. in this study is presented the first case of trombiculiasis caused by the infestation of chigger mite eutrombicula in alpacas from peru. twenty-two alpacas of a total of 130 animals were infested by eutrombicula sp. the chigger mite location was only in the face skin folds and around the eyes. in addition, all alpacas infested had alopecia and dermatitis in the infected zone.201222770680
topographic distribution of the sand flea tunga penetrans in wistar rats and humans in two endemic areas in brazil.tungiasis is a zoonosis caused by tunga penetrans. in brazil, tungiasis is endemic in many resource-poor communities, in which various domestic and sylvatic animals act as reservoirs. eighty laboratory-raised wistar rats were exposed to t. penetrans in areas of intense transmission: a fishing village and an urban shantytown in ceará state, northeast brazil. the topographic distribution of lesions in wistar rats was compared with the distribution of lesions in humans in the same area. our results ...201222764302
life-threatening scrub typhus with hemophagocytosis and acute respiratory distress syndrome in an infant.scrub typhus is a rickettsial disease, caused by orientia tsutsugamushi, which is transmitted via the bite of a chigger. this disease is one of the most important infectious diseases in the asia-pacific area; however, a severe infant case has not yet been reported. here, we present the case of an 8-month-old boy with scrub typhus accompanied by hemophagocytic lymphohistiocytosis (hlh). his rapid course was complicated by acute respiratory distress syndrome (ards), status epilepticus and dissemin ...201322735791
dermoscopy: ex vivo visualization of fleas head and bag of eggs confirms the diagnosis of tungiasis.tungiasis, caused by the impregnated female sand flea tunga penetrans, is increasingly common in returned travellers from endemic areas. clinical suspicion is raised by the clinicodermoscopic correlation, leading to rapid treatment which involves extraction of the intact flea. ex vivo dermoscopy demonstrates the parasite's head and distended abdomen full of eggs, confirming the diagnosis.201222571560
variable clinical responses of a scrub typhus outbred mouse model to feeding by orientia tsutsugamushi infected mites.rodents are the natural hosts for leptotrombidium mites that transmit orientia tsutsugamushi, the causative agent of scrub typhus, a potentially fatal febrile human disease. utilizing mite lines that included o. tsutsugamushi infected and non-infected leptotrombidium species we investigated the varied infection response of outbred mice (icr) exposed to l. chiangraiensis (lc), l. imphalum (li) and l. deliense (ld). each of six mite lines (lc1, lc5, li3, li4, li7 and ld) was separately placed in t ...201222527840
tunga penetrans acquired while traveling in africa.three cases of tungiasis acquired in the course of travel are briefly described, and the biology of the jigger flea, tunga penetrans, is reviewed.199422451770
ectoparasites of small mammals in four localities of wildlife reserves in peninsular malaysia.field surveys of ectoparasites on rodents and scandents were conducted in four localities of wildlife reserves in peninsular malaysia from october 2008 to november 2009. a total of 16 animals comprising 5 species of hosts were caught and examined for ectoparasites. the hosts examined were maxomys rajah, maxomys whiteheadi, leopoldamys sabanus, lariscus insignis and tupaia glis. of these hosts, 9 genera, consisting of 14 species of ectoparasites were extracted. three species of ticks (ixodidae), ...201122299462
Disseminated tungiasis.Tungiasis is a zoophilic and anthropophilic infestation caused by Tunga penetrans. It is endemic in Latin America and in the Caribbean. It occurs mainly in impoverished communities that have no access to basic sanitation and in individuals that visit contaminated areas. The most common penetration site of this ectoparasite is the periungueal region of the feet. The authors present its disseminated form occurring in a patient inhabiting a rural area.201122147051
Macrocyclic Lactones in the Treatment and Control of Parasitism in Small Companion Animals.Macrocyclic lactones (MLs) have many anti-parasitic applications in small companion animal medicine. They were first developed as chemoprophylactics against heartworm (Dirofilaria immitis) infection to be applied monthly for retroactive killing of third- and fourth-stage larvae. ML-containing products formulated for oral (ivermectin, milbemycin oxime), topical (selamectin, moxidectin) or injectable sustained release (moxidectin, ivermectin) are approved for heartworm prevention in dogs or cats ...201122039798
Emergence of Schoengastiella ligula as the vector of scrub typhus outbreak in Darjeeling: has Leptotrombidium deliense been replaced?Following a suspected outbreak of scrub typhus in Kurseong, Darjeeling, the Armed Forces Medical College, Pune was requested by the National Institute of Epidemiology and the State authorities to undertake investigation of the ongoing scrub typhus outbreak and suggest containment measures.201121941043
tungiasis in a free-ranging jaguar (panthera onca) population in brazil.tungiasis is an ectoparasitic disease caused by fleas of the genus tunga. the disease is reported to occur mostly in human populations. in wildlife, however, the occurrence and impact of this disease remains uncertain. we captured and examined 12 free-ranging jaguars for the presence of tunga penetrans in the pantanal region of mato grosso do sul state, brazil. tungiasis prevalence was 100% in the population; lesions were confined to the jaguar's paws. t. penetrans was identified based on the ch ...201121863398
[tungiasis: a case report].tungiasis, is a cutaneous parasitosis, native of america caused by tunga penetrans. infestations usually presents with black papular lesions, either single or multiple, most of them localized on the feet, mainly in the subungual and periungual areas. diagnosis of tungiasis is based on the characteristic aspect of the lesions in a patient coming from an endemic area. surgical removal of the fea and application of a topical antibiotic is the standard treatment. we describe a case of a 10-years-old ...201121829863
[preliminary analysis of chigger mite community on eothenomys miletus in 19 counties of yunnan province].eothenomys miletus were captured in 19 counties of yunnan province. the distribution of species-abundance and the species-plots relationship between e. miletus and chigger mites were analyzed by using ecological statistic method. there were totally 40,052 chigger mites collected from the body surface of 1741 e. miletus. 111 species of chigger mites were identified. the species-abundance distribution showed that with the increase of mite individuals, the number of chigger mite species gradually d ...201121826908
Tungiasis in a beach volleyball player: a case report.Tungiasis is an infestation caused by penetration of the skin by the gravid female of the flea Tunga penetrans Linnaeus 1758 (Insecta, Siphonaptera: Tungidae). Tunga penetrans is currently found in Central and South America, sub-Saharan Africa, and Central Asia. Prevalence is very high in Brazil. We present a case of tungiasis in an Italian beach volleyball player who acquired the infestation in Brazil.201121817006
chiggers recently infesting spea spp. in texas, usa, were eutrombicula alfreddugesi, not hannemania sp.upon re-examination of preserved larval chiggers collected from spadefoot toads (spea bombifrons and spea multiplicata) in the southern high plains of texas, usa, and identified previously as hannemania sp., we found them to be eutrombicula alfreddugesi. a review of previous reports of eutrombicula spp. chiggers on amphibian hosts provides context for current findings. all members of the genus hannemania are specialized larval parasites of amphibians, whereas larval e. alfreddugesi are generalis ...201121719825
tungiasis: a poorly documented tropical dermatosis.tungiasis is the parasitic skin disease caused by the sand flea tunga penetrans, also called the jigger flea, found in most intertropical countries. the contamination occurs when walking barefoot in the sand: adult females actively burrow the foot epidermis leading to self-limited lesions responsible for itching or pain. the diagnosis is made on clinical observation and history of travelling to an endemic country. the simple treatment is surgical extraction of the flea.201121703785
spatial analysis of scrub typhus infection and its association with environmental and socioeconomic factors in taiwan.we analyzed the spatial distribution of human cases of scrub typhus on the main island of taiwan from 2003 to 2008 and implemented an island-wide survey of scrub typhus vectors (trombiculid chiggers) in 2007 and 2008. the standardized incidence rate 'sir' incorporating inter-district variations in population, gender and age was correlated with environmental and socioeconomic variables. higher incidence and sir rates were clustered in the less developed, mountainous regions of central and eastern ...201121703220
[preliminary survey on the distribution of leptotrombidium deliense in some areas of yunnan province.]objective: to investigate the distribution of leptotrombidium deliense among different small mammal hosts in some areas of yunnan province. methods: a field survey was carried out in some counties of yunnan province and the small mammal hosts were captured, using mouse cages and traps with baits. chigger mites on the surface of two auricles were scraped off by a bistoury, and then preserved in 70% ethanol. every specimen of the chigger mites on the slides was finally identified into species unde ...201121518533
arthropod symbiotes of laonastes aenigmamus (rodentia: diatomyidae).abstract arthropod symbiotes of the laotian rock-rat, laonastes aenigmamus (rodentia: diatomyidae), from laos are examined. this host is a member of diatomyidae previously thought to have gone extinct >10 million yr ago. permanent symbiotes are represented by 2 species, a new species of sucking louse, polyplax sp., near rhizomydis (phthiraptera: polyplacidae), and a new species of fur mite, afrolistrophorus sp., near maculatus (acariformes: listrophoridae). the temporary parasites are represente ...201121506873
isolation and characterization of orientia tsutsugamushi from rodents captured following a scrub typhus outbreak at a military training base, bothong district, chonburi province, central thailand.orientia tsutsugamushi, an obligate intracellular gram-negative bacterium, is the causative agent of scrub typhus, a vector-borne disease transmitted by infected chiggers (trombiculid mite larvae). in 2002, an outbreak of scrub typhus occurred among royal thai army troops during the annual field training at a military base in bothong district, chonburi province, central thailand. this report describes the outbreak investigation including its transmission cycle. results showed that 33.9% of 174 t ...201121460017
detection of orientia tsutsugamushi, the causative agent of scrub typhus, in a novel mite species, eushoengastia koreaensis, in korea.to identify potential vector species of scrub typhus in the republic of korea (rok), chigger mites were harvested from wild rodents captured at nine localities in october 2005. the bodies of the chigger mites were individually punctured with a fine pin, squeezed out internal contents, and examined for orientia tsutsugamushi dna by nested polymerase chain reaction. the exoskeleton of associated chiggers was mounted on glass slides with polyvinylalcohol (pva) medium for identification. among 830 i ...201121443412
genetic typing, based on the 56-kilodalton type-specific antigen gene, of orientia tsutsugamushi strains isolated from chiggers collected from wild-caught rodents in taiwan.orientia tsutsugamushi is the etiological agent of scrub typhus, a mite-borne, febrile illness that occurs in the asia-pacific region. we conducted strain characterization of o. tsutsugamushi isolates from chiggers obtained from rodents based the nucleotide sequence of the 56-kda outer membrane protein gene. with the use of pcr, a total of 68 dna sequences of 56-kda antigen genes were amplified. phylogenetic analysis revealed that there were at least six definable clusters among the 68 isolates: ...201121441323
medical microbiologyrickettsiae are small, gram-negative bacilli that have evolved in such close association with arthropod hosts that they are adapted to survive within the host cells. they represent a rather diverse collection of bacteria, and therefore listing characteristics that apply to the entire group is difficult. the common threads that hold the rickettsiae into a group are their epidemiology, their obligate intracellular life ...199621413251
surveys of rodent-borne disease in thailand with a focus on scrub typhus assessment.the epidemiology of many rodent-borne diseases in south-east asia remains ill-defined. scrub typhus and lep-tospirosis are common and medically significant, while other zoonotic diseases, such as spotted fever group rickettsiae have been identified, but their overall medical significance is unknown. rodent surveillance was conducted from june 2002 to july 2004 in 18 provinces from thailand. traps were set up for one to three nights. blood and serum samples and animal tissue samples (liver, splee ...200821396076
first reports of ectoparasites collected from wild-caught exotic reptiles in florida.we collected ectoparasites from 27 of 51 wild-caught, free-ranging exotic reptiles examined in florida from 2003 to 2008. sampled animals represented eight species, five of which yielded ectoparasites. reported new parasite distribution records for the united states include the following: the first collection of the african tick amblyomma latum (koch) from a wild-caught animal [ball python, python regius (shaw)] in the united states; the first collection of the lizard scale mite hirstiella stami ...201121337954
imported tungiasis in a japanese student returning from east africa.ectoparastiosis by tunga penetrans is becoming more common in non-tropical countries as people travel more to endemic areas. we present here a classic case of imported tungiasis including a history of visit to an endemic region and its typical presentation. diagnosis with dermoscopy, treatment and prevention are discussed.201021269317
identification of potential hosts and vectors of scrub typhus and tick-borne spotted fever group rickettsiae in eastern taiwan.scrub typhus and tick-borne spotted fever group (sfg) rickettsioses are transmitted by chiggers (larval trombiculid mites) and hard ticks, respectively. we assessed exposure to these disease vectors by extensively sampling both chiggers and ticks and their small mammal hosts in eastern taiwan during 2007 and 2008. the striped field mouse apodemus agrarius pallas (rodentia: muridae) was the most common of the small mammals (36.1% of 1393 captures) and presented the highest rate of infestation wit ...201121223345
tunga penetrans: painful lesions on the feet-the first imported case from guinea-bissau.tungiasis is an endemic disease in certain poor areas around the world. imported infestations in travelers are becoming more frequent and can lead to considerable morbidity. we report a case of a 50 year-old-man who returned from a trip to guinea-bissau with an infection caused by tunga penetrans.201021209743
control of tungiasis through intermittent application of a plant-based repellent: an intervention study in a resource-poor community in brazil.tungiasis, an ectoparasitosis caused by the female sand flea tunga penetrans, is an important health problem in many impoverished communities in the tropics. sand flea disease is associated with a broad spectrum of clinical pathology and severe sequels are frequent. treatment options are limited.201021085467
laboratory evaluation of four commercial repellents against larval leptotrombidium deliense (acari: trombiculidae).four commercial repellents were evaluated in the laboratory against leptotrombidium deliense chiggers. both in vitro and in vivo methods were used to determine repellency of the compounds. the repellents were kellis (containing citronella oil, jojoba oil and tea tree oil), kaps (containing citronella oil), bioz (containing citronella oil, geranium oil and lemon grass oil) and off (containing deet). the combination of three active ingredients: citronella oil, geranium oil, lemon grass oil gave th ...201021073028
materials as effective as benzyl benzoate for impregnating clothing against chiggers. 194621065124
tunga penetrans--egg head? 201021062608
a new genus and species of chigger, chatia setosa (trombiculidae, acarina) from northwestern united states. 194621027501
a method of rearing chigger mites (acarina, trombiculinae). 194621020344
a contribution to our knowledge of the bionomics of the common north american chigger, eutrombicula alfred-dugesi (oudemans) with a description of a rapid collecting method. 194621020343
insecticides applied to forest litter to control new guinea chiggers. 194620996710
tests against chiggers in new guinea to develop a practical field method for impregnating uniforms with dimethyl phthalate for scrub typhus prevention. 194620985365
variation within and among host species in engorgement of larval trombiculid mites.we recovered larval trombiculid mites (i.e. chiggers), vectors of scrub typhus, from small mammal hosts in taiwan, and compared the relative degree of engorgement (rde) of the dominant chigger (leptotrombidium imphalum) from different hosts. naturally occurring chiggers recovered from rattus losea and bandicota indica were 1·4x and 1·3x as engorged as those from apodemus agrarius. within each host species, rde was negatively related to chigger loads, but was mostly unrelated to gender or to body ...201020946695
[tungiasis in native amerindians in vaupés province: epidemiology, clinical aspects, treatment, and prevention].tungiasis, the skin infestation with the flea tunga penetrans, occurs in poor communities. objective. to present a study of this condition among native amerindians from vaupés (colombia).201020890569
serosurveillance of scrub typhus in small mammals collected from military training sites near the dmz, northern gyeonggi-do, korea, and analysis of the relative abundance of chiggers from mammals examined.comprehensive quarterly serosurveillance on scrub typhus in small mammals collected from military training sites located near the demilitarized zone (dmz), northern gyeonggi-do (province), rok was conducted to determine the potential rodent-borne and associated ectoparasite disease risks to military personnel. a total of 1,196 rodents and insectivores representing 8 species, apodemus agrarius (87.3%, n = 1,044), mus musculus (5.4%, n = 65), crocidura lasiura (3.3%, n = 40), microtus fortis (2.6% ...201020877503
the role of the united states military in the development of vector control products, including insect repellents, insecticides, and bed nets.arthropod-borne diseases such as malaria, dengue, scrub typhus, and leishmaniasis continue to pose a significant threat to u.s. military forces deployed in support of operational and humanitarian missions. these diseases are transmitted by a variety of arthropods, including mosquitoes, ticks, chiggers, sand flies, and biting midges. in addition to disease threats, biting arthropods can cause dermatitis, allergic reactions, and sleep loss; therefore, monitoring of vector impact and integrated use ...200920836805
phylogenetic analysis of 56-kda type-specific antigen gene of orientia tsutsugamushi isolates in taiwan.scrub typhus is a rickettsial disease transmitted to humans through the bite of chigger mites infected with orientia tsutsugamushi, and is an endemic disease in taiwan. to elucidate the molecular epidemiology of o. tsutsugamushi, the complete open reading frame of the 56-kda type-specific antigen gene sequence of strains isolated from scrub typhus patients were determined and analyzed. a total of 116 isolates of o. tsutsugamushi were successfully isolated from patients infected in diverse geogra ...201020810835
chigger mites (acari, trombiculidae) parasitizing small mammals in the eastern hindu kush and some other afghan areas.chigger mites of afghanistan were studied on the base of collections made in eastern and central hindu kush, kabul, and some other localities. fifteen chigger species parasitizing nine species of rodentia, two species of lagomorpha, and one species of soricomorpha were found, including 13 species which were not previously recorded in afghanistan. eco-geographical variability is observed in shunsennia oudemansi: individuals of this species from high-mountain localities of eastern hindu kush are c ...201020737277
a revision of chiggers of the minuta species-group (acari: trombiculidae: neotrombicula hirst, 1925) using multivariate morphometrics.we revise chiggers belonging to the minuta-species group (genus neotrombicula hirst, 1925) from the palaearctic using size-free multivariate morphometrics. this approach allowed us to resolve several diagnostic problems. we show that the widely distributed neotrombicula scrupulosa kudryashova, 1993 forms three spatially and ecologically isolated groups different from each other in size or shape (morphometric property) only: specimens from the caucasus are distinct from those from asia in shape, ...201020700698
endemic mite-transmitted dermatoses and infectious diseases in the south.mites are mostly ubiquitous, bothersome pests with few species of medical importance and, of these, most are scabies mites, trombiculid larval mites and animal and plant mites. all patients with scabies and their close household, institutional and sexual contacts should be informed that scabies is a highly transmissible ectoparasitic infestation and that several topical treatments and an effective oral treatment are readily available and highly effective at present. sexually active patients with ...201020666166
occurrence of the off-host life stages of tunga penetrans (siphonaptera) in various environments in brazil.to explore the local transmission dynamics of tunga penetrans in brazil, 134 soil samples from various environments were collected in three different endemic regions of the country and checked for the presence of the flea's larvae, pupae and adults. the samples, which came from an urban slum in the north-east, a village of xavante indians in the central-west and a community of yanomami indians living in traditional longhouses (malocas) in the north, were categorized as indoor, outdoor or indoor- ...201020659395
tungiasis: case report of a traveller to kenya.tungiasis is a neglected parasitic skin disease caused by the permanent penetration of the female sand flea tunga penetrans (also called jigger flea) into the skin of its host. growing urbanisation, improved housing and the use of appropriate footwear have presumably led to an overall reduction of the occurrence of this ectoparasitosis within the last few decades. however, it is still highly prevalent in regions where people live in extreme poverty, such as in many latin american and african cou ...200920652110
tungiasis infestation in tanzania.tungiasis is caused by the jigger flea tunga penetrans. we describe a case of severe infestation from kigoma region, western tanzania. a 19-year-old male with epilepsy and mental disability presented with ulcerated and inflamed toes. clinical examination revealed the presence of approximately 810 embedded jigger fleas on the feet, and another 60 lesions on the hands. the patient presented with fissures on the feet, hands and soles. he had difficulty walking and erythematous, oedematous, ulcerate ...201020351463
chigger repellents. 194620273618
studies on north american chiggers; the subfamilies and womersia strandtmani n.g., n.sp. 194720256992
studies on north american chiggers; the akamushi group. 194720245745
new species of chiggers (a-carina, trombiculidae) from bats of the nearctic region. 194720245743
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