Publications

the hepatoprotective effects of taiwan folk medicine ham-hong-chho in rats.	bidens pilosa l. var minor (blume) sherff, b. pilosa l. and b. chilensis dc (compositae), commonly known as "ham-hong-chho" in taiwan, have been traditionally used for medicinal purposes. to clarify and compare the hepatoprotective effects of these three plants, we evaluated their potential effectiveness on ccl4- and acetaminophen-induced acute hepatic lesions in rats. the results indicated that the increase in sgot and sgpt activities caused by ccl4 (3.0 ml/kg, s.c.) and acetaminophen administr ...	1996	8982435
the protective effect of alstonia scholaris r. br. on hepatotoxin-induced acute liver damage.	the hepatoprotective effect of alstonia scholaris r. br. on liver injuries induced by carbon tetrachloride (ccl4). beta-d-galactosamine, acetaminophen and ethanol were investigated by means of serum-biochemical and histopathological examinations. post treatment of a scholaris reduced dose-dependently the elevation of serum transaminases level and histopathological changes such as cell necrosis, inflammatory cell infiltration, which were caused by the single administration of 32 microliters/kg cc ...	1996	8874672
hepatoprotective effects of taiwan folk medicine: wedelia chinensis on three hepatotoxin-induced hepatotoxicity.	the hepatoprotective effects of a taiwanese crude herb, hwang-hua-mih-tsay (wedelia chinensis (osbeck) merr.), were investigated. acute hepatitis was induced by three hepatotoxins: carbon tetrachloride and acetaminophen in mice, and d(+)-galactosamine in rats. after treatment with w. chinensis (300 mg/kg, p.o.) at 2, 6 and 10 hours, a reduction in the elevation of serum glutamate oxaloacetic transaminase (sgot) and glutamate pyruvic transaminase (sgpt) levels was observed at 24 hrs after hepatot ...	1994	7992815
hepatoprotective effects of taiwan folk medicine: ixeris chinensis (thunb.) nak. on experimental liver injuries.	the hepatoprotective effects of ixeris chinensis (thunb.) nak. were studied on acute hepatitis induced in mice by a single dose of carbon tetrachloride (31.25 microliters/kg, ip) or acetaminophen (600 mg/kg, ip), and in rats by a single dose of beta-d-galactosamine (188 mg/kg, ip). hepatoprotective activity was monitored by estimating the serum transaminases (sgot and sgpt) levels and histopathological changes in the livers of experimental animals. the ixeris chinensis (thunb.) nak. extracts sig ...	1994	7872236
[comparative studies on the roots of wild and cultured bupleurum chinense dc].		1988	3264223
the pharmacological and pathological studies on several hepatic protective crude drugs from taiwan (i).	this study is to investigate the hepatic protective effect of several taiwan crude drug extractions on the carbon tetrachloride (ccl4)-induced hepatotoxicity in rats. the pharmacological and pathological effects of bupleurum chinense, phellodendron wilsonii, clematis chinensis and hedyotis corymbosa were analyzed by liver enzyme function test and pathological studies. however, the results of amine transferase sgot and sgpt have shown a significant hepatic protective effect after treatment with b ...	1988	3245533
[comparison on saikosaponin levels in the root of bupleurum chinense of various sizes].		1985	2933158
[preliminary study of traditional chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases].	this paper reports the clinical treatment of 100 patients with minimal brain dysfunction (mbd), their age ranged from 7-14.2 years, and the average age was 10.5. patients were divided into tcm and wm group randomly. the tcm group (80 cases) were treated with the therapy of subdueing hyperactivity of the liver and invigorating the function of the spleen by using: bupleurum chinense, scutellaria baicalensis, astragalus membranaceus, codonopsis pilosula, ligustrum lucidum, lophatherum gracile and t ...	1990	2397543
the pharmacological and pathological studies on taiwan folk medicine (iv): the effects of echinops grijisii and e. latifolius.	the protective effect of "san-fang-feng" derived from the root of echinops grijsii hance on ccl4-induced hepatotoxicity has been studied. this crude drug was found to possess a marked hepatoprotective effect. a comparison of the protective effect with "lou-lu" derived from the root of e. latifolius tausch and "pei-chai-hu" original bupleurum chinense showed that e. grijisii and e. latifolius were more effective than b. chinense as reported previously. the results suggested that both e. grijisii ...	1990	2270845
the pharmacological and pathological studies on taiwan folk medicine (iii): the effects of bupleurum kaoi and cultivated bupleurum falcatum var. komarowi.	the protective effects of water extract from roots of bupleurum kaoi liu, chao et chuang and bupleurum flacatum l. var. komarowi koso-polj on ccl4-induced hepatoxicity have been investigated. both b. kaoi (p less than 0.05) and b. falcatum var. komarowi (p less than 0.01) possessed more marked anti-hepatotoxic pharmacological effects than bupleurum chinense dc., the typical strain widely used in taiwan. the pathological improvement from treatment by means of the three drugs to alleviate ccl4-ind ...	1990	2270844
the pharmacological and pathological studies on taiwan folk medicine (vi): the effects of elephantopus scaber subsp. oblanceolata, e. mollis and pseudoelephantopus spicatus.	the liver protective effect of elephantopus scaber subsp. oblanceolata, e. mollis and pseudoelephantopus spicatus on ccl4 induced hepatotoxicity has been determined by liver enzyme functional test and pathological studies. as the result indicated, the acute increase of serum transaminase (sgot and sgpt level which was caused by ccl4 administration (3.0ml/kg, s.c.) can be significantly reduced when treating with e. scaber subsp. oblanceolata (p less than 0.001), e. mollis (p less than 0.01), p. s ...	1991	1897489
[dynamic variation of saikosaponin contents].	in this paper both the cultivated and wild bupleurum chinense and b. scorzonerifolium from northeast china of different growing periods and ages were analyzed for the contents of saikosaponins a and d by hplc and total saikosaponins by spectrophotometry. the results indicated that the saikosaponin content of b. chinense was higher than that of b. scorzonerifolium, and that the saikosaponin contents of the cultivated species were higher than or almost equal to those of the wild ones. it was also ...	1991	1804165
anatomical and histological studies of bupleuri radix.	three kinds of bupleuri radix were found in taiwan. to clarify their origins, histological studies were carried out to identify their internal and external structures. it was found that bupleuri radix or "chai-hu" of taiwan is derived from roots of the following species" 1, bupleurum chinense which was imported from china, 2, bupleurum falcatum var. komarowi a cultivated production of japanese origin, and 3, bupleurum kaoi which is indigenous to taiwan. these bupleuri radix were easily assigned ...	1991	1767798
pharmacological and pathological studies on hepatic protective crude drugs from taiwan (v): the effects of bombax malabarica and scutellaria rivularis.	bombax malabarica dc and scutellaria rivularis b. were extracted in boiling water and concentrated into 1g/ml solution to investigate their hepatoprotective effect. carbon tertrachloride (ccl4) was injected into rat subcutaneously with a dose of 3.0 ml/kg to induce experimental acute hepatotoxicity in the animal. the activities of serum glumtamic-oxaloacetic transaminase (sgot) and serum glutamicpyruvic transaminase (sgpt) were measured after 72 hours of ccl4 administration. the hepatopathologic ...	1992	1471609