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medicinal plants and dementia therapy: herbal hopes for brain aging?an escalating "epidemic" of diseases like alzheimer's has not yet been met by effective symptomatic treatments or preventative strategies. among a few current prescription drugs are cholinesterase inhibitors including galantamine, originating from the snowdrop. research into ethnobotanicals for memory or cognition has burgeoned in recent years. based on a multi-faceted review of medicinal plants or phytochemicals, including traditional uses, relevant bioactivities, psychological and clinical evi ...201122070157
effect of aromatherapy on the quality of sleep in ischemic heart disease patients hospitalized in intensive care units of heart hospitals of the isfahan university of medical sciences.sleep disorder is one of the common problems patients face in icu and ccu and it is usually treated by sleeping pills. nowadays, the complementary medicine is highly considered because of its effectiveness and safety. aromatherapy is one of the holistic nursing cares which sees human beings as a biological, mental and social unit while the psychological dimension has the central role. each of these dimensions is dependent on each other and is affected by each other. therefore, it is fundamental ...201022049287
aroma-therapeutic effects of massage blended essential oils on humans.although blended essential oils are increasingly being used for the improvement of the quality of life and for the relief of various symptoms in patients, the scientific evaluation of the aroma-therapeutic effects of blended essential oils in humans is rather scarce. in this study, we hypothesized that applying blended essential oil would provide a synergistic effect that would have a chance for success in treating depression or anxiety. therefore, the main objective of this study was to investi ...201121922934
common complementary and alternative therapies with potential use in dermatologic surgery: risks and benefits.ambulatory surgery patients often use complementary and alternative medicine (cam) therapies. cam therapies may create beneficial and detrimental perioperative conditions.201321890235
an ex vivo, assessor blind, randomised, parallel group, comparative efficacy trial of the ovicidal activity of three pediculicides after a single application--melaleuca oil and lavender oil, eucalyptus oil and lemon tea tree oil, and a "suffocation" pediculicide.there are two components to the clinical efficacy of pediculicides: (i) efficacy against the crawling-stages (lousicidal efficacy); and (ii) efficacy against the eggs (ovicidal efficacy). lousicidal efficacy and ovicidal efficacy are confounded in clinical trials. here we report on a trial that was specially designed to rank the clinical ovicidal efficacy of pediculicides. eggs were collected, pre-treatment and post-treatment, from subjects with different types of hair, different coloured hair a ...201121864348
volatile chemical composition and bioactivity of six essential oils against the stored food insect sitophilus zeamais motsch. (coleoptera dryophthoridae).essential oils (eos) of achillea millefolium, myrtus communis, rosmarinus officinalis, helichrysum italicum, foeniculum vulgare and lavandula angustifolia were analysed with gc-fid and gc-ms in order to define their aromatic profiles and then their toxicity and repellent activity against sitophilus zeamais motsch. (coleoptera dryophthoridae) with specific bioassays were evaluated. results from topical applications on insects showed that all eos had variable and significant insecticidal activity. ...201121861644
the effect of lavender oil on serum testosterone levels and epididymal sperm characteristics of formaldehyde treated male rats.in this study, the harmful effects of formaldehyde (fa) on serum testosterone levels and epididymal sperm characteristics were investigated. in addition, possible protective effect of lavender oil was evaluated.201121744749
study of organic honey from the northeast portugal.concerns about traces of numerous toxic substances and authenticity have prompted consumer demand for honey that is certified as organic, based on strict ecological, natural principles and traceability. the present study aims to characterize organic honey samples (n = 73) from northeast portugal, with respect to floral nectar origin, physicochemical parameters and microbial safety. the phenols and flavonoids contents, often referred to as responsible for honey's bioactive properties, were also a ...201121709620
antioxidant capacity and total phenolic contents of oregano (origanum vulgare), lavender (lavandula angustifolia) and lemon balm (melissa officinalis) from romania.the study reported here presents a comparative screening of three medicinal plants including oregano (origanum vulgare l.), lavender (lavandula angustifolia) and lemon balm (melissa officinalis) having the same geographical origin, the southeast region of romania, and growing in the same natural conditions. the contents of total phenolics and total flavonoids for the extracts of these were determined. furthermore, the total antioxidant capacity was also evaluated. it was found that origanum vulg ...201121707233
[histo-anatomical researches of two subspecies of lavandula angustifolia mill].the structure of the inflorescences of two subspecies of lavandula angustifolia sl. angustifolia ssp. angustifolia and. l. angustifolia ssp. pyrenaica (d.c.) guinea+ú was studied to determine the range of variation in certain histo-anatomical characters.201121688584
chlordiazepoxide and lavender oil alter unconditioned anxiety-induced c-fos expression in the rat brain.lavender oil has a long history of use for treating anxiety, but only recent research has examined its effects using standard behavioural methods used to test novel drugs. the aim of this study was to investigate the effects of inhaled lavender oil on anxiety related behaviour of rats in the open field and to compare them with the effects of chlordiazepoxide (cdp), a typical anxiolytic drug. additionally c-fos immunochemistry was used to investigate whether lavender oil produced the same pattern ...201121641938
vitamin c and sugar levels as simple markers for discriminating spanish honey sources.in this work, 7 spanish honeys with different botanical origins were studied. the honey origins were rosemary, chestnut, lavender, echium, thyme, multifloral, and honeydew. the chemical compounds determined were ascorbic acid (vitamin c), hydroxymethylfurfural, and major sugar contents (glucose and fructose). the physicochemical parameters, ph, conductivity, moisture, free acidity, and color, were also measured. vitamin c is an important antioxidant in food, and the possibility to use it as disc ...201121535800
application of high-performance liquid chromatography diode array detection and mass spectrometry to the analysis of characteristic compounds in various essential oils.a high-performance liquid chromatography (hplc) method was established using an analytical reversed-phase column and gradient elution to achieve chromatographic separation of typical compounds in essential oils. for detection, a diode array detector monitoring different wavelengths simultaneously as well as a mass spectrometer (ms) were used. atmospheric pressure chemical ionization operating in the positive mode turned out to be a suitable tool to detect volatiles of different chemical classes ...201121499677
aqueous extract of lavender (lavandula angustifolia) improves the spatial performance of a rat model of alzheimer's disease.alzheimer's disease (ad) is one of the most important neurodegenerative disorders. it is characterized by dementia including deficits in learning and memory. the present study aimed to evaluate the effects of aqueous extract of lavender (lavandula angustifolia) on spatial performance of ad rats.201121441971
herbal medicines, other than st. john's wort, in the treatment of depression: a systematic review.to evaluate herbal medicines, other than st. john's wort, in the treatment of depression. data sources/search methods: a computer-based search of medline, cinahl, amed, alt health watch, psych articles, psych info, current contents databases, cochrane controlled trials register, and cochrane database of systematic reviews, was performed. researchers were contacted, and bibliographies of relevant papers and previous meta-analysis were hand searched for additional references.201121438645
substrate promiscuity of a rosmarinic acid synthase from lavender (lavandula angustifolia l.).one of the most common types of modification of secondary metabolites is the acylation of oxygen- and nitrogen-containing substrates to produce esters and amides, respectively. among the known acyltransferases, the members of the plant bahd family are capable of acylating a wide variety of substrates. two full-length acyltransferase cdnas (laat1 and 2) were isolated from lavender flowers (lavandula angustifolia l.) by reverse transcriptase-pcr using degenerate primers based on bahd sequences. re ...201121424826
patent literature on mosquito repellent inventions which contain plant essential oils--a review.bites bites of mosquitoes belonging to the genera anopheles meigen, aedes meigen, culex l. and haemagogus l. are a general nuisance and are responsible for the transmission of important tropical diseases such as malaria, hemorrhagic dengue and yellow fevers and filariasis (elephantiasis). plants are traditional sources of mosquito repelling essential oils (eos), glyceridic oils and repellent and synergistic chemicals. a chemical abstracts search on mosquito repellent inventions containing plant- ...201121328177
cloning and functional characterization of β-phellandrene synthase from lavandula angustifolia.en route to building genomics resources for lavandula, we have obtained over 14,000 ests for leaves and flowers of l. angustifolia, a major essential oil crop, and identified a number of previously uncharacterized terpene synthase (tps) genes. here we report the cloning, expression in e. coli, and functional characterization of β-phellandrene synthase, laβphls. the orf--excluding the transit peptide--for this gene encoded a 62.3 kda protein that contained all conserved motifs present in plant tp ...201021165645
[effects of aromatherapy on changes in the autonomic nervous system, aortic pulse wave velocity and aortic augmentation index in patients with essential hypertension].to investigate the effectiveness of aromatherapy on blood pressure, heart rate variability, aortic pulse wave velocity and the aortic augmentation index of essential hypertensive patients.201021157172
pleiotropic effects of pigmentation genes in horses.horses are valued for the beauty and variety of colouration and coat patterning. to date, eleven different genes have been characterized that contribute to the variation observed in the horse. unfortunately, mutations involving pigmentation often lead to deleterious effects in other systems, some of which have been described in the horse. this review focuses on six such pleiotropic effects or associations with pigmentation genes. these include neurological defects (lethal white foal syndrome and ...201021070283
antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model.the chemical composition and antibacterial activity of essential oils from 10 commonly consumed herbs: citrus aurantium, c. limon, lavandula angustifolia, matricaria chamomilla, mentha piperita, m. spicata, ocimum basilicum, origanum vulgare, thymus vulgaris and salvia officinalis have been determined. the antibacterial activity of these oils and their main components; i.e. camphor, carvacrol, 1,8-cineole, linalool, linalyl acetate, limonene, menthol, a-pinene, b-pinene, and thymol were assayed ...201021030907
skin application of urea-containing cream affected cutaneous arterial sympathetic nerve activity, blood flow, and water evaporation.we observed that olfactory stimulation with scent of grapefruit oil elevated the activities of sympathetic nerves, and increased the plasma glycerol concentration and blood pressure. in contrast, olfactory stimulation with scent of lavender oil had opposite effects in rats. these suggest that changes in autonomic activities cause physiological functions via histaminergic h1 and h3 receptor. moreover, it has been reported that somatic sensory stimulation affected autonomic neurotransmission. to e ...201120923465
volatile fraction of lavender and bitter fennel infusion extracts.the relative proportions of chemical classes (hydrocarbons, oxides, alcohols/ethers, aldehydes/ketones, acids/esters/lactones) in the essential oil of lavender (lavendula angustifolia mill., family lamiaceae) and bitter fennel (foeniculum vulgare mill. subsp. vulgare var. vulgare (mill.) thellung, family apiaceae) and in the volatile fraction of infusion extracts were examined and showed remarkable differences. the volatile compounds of infusions were isolated by hydrodistillation and solid phas ...201020923003
herbicidal activity of volatiles from coriander, winter savory, cotton lavender, and thyme isolated by hydrodistillation and supercritical fluid extraction.the volatiles from coriandrum sativum l., satureja montana l., santolina chamaecyparissus l., and thymus vulgaris l. were isolated by hydrodistillation (essential oil) and supercritical fluid extraction (volatile oil). their effect on seed germination and root and shoot growth of the surviving seedlings of four crops ( zea mays l., triticum durum l., pisum sativum l., and lactuca sativa l.) and two weeds ( portulaca oleracea l. and vicia sativa l.) was investigated and compared with those of two ...201020886818
proboscis conditioning experiments with honeybees, apis mellifera caucasica, with butyric acid and deet mixture as conditioned and unconditioned stimuli.three experiments are described investigating whether olfactory repellents deet and butyric acid can support the classical conditioning of proboscis extension in the honeybee, apis mellifera caucasica (hymenoptera: apidae). in the first experiment deet and butyric acid readily led to standard acquisition and extinction effects, which are comparable to the use of cinnamon as a conditioned stimulus. these results demonstrate that the odor of deet or butyric acid is not intrinsically repellent to h ...201020879917
evaluation of antioxidant potential of lavandula x intermedia emeric ex loisel. 'budrovka': a comparative study with l. angustifolia mill.a croatian indigenous cultivar of lavandin, lavandula x intermedia 'budrovka' (lamiaceae) was studied for the phenolic acids, flavonoids, anthocyanins, procyanidins and total tannins, as well as total polyphenols content, in the flower, inflorescence stalk and leaf ethanolic extracts. antioxidant potentials on these plant part extracts were assessed by the dpph free radical scavenging activity, iron chelating activity, reducing power, lipid peroxidation inhibition properties and total antioxidan ...201020877203
an attempt of postharvest orange fruit rot control using essential oils from mediterranean plants.twelve essential oils from mediterranean aromatic plants were tested at different doses against four fungi known as causal agents of post-harvest orange fruit rot: botrytis cinerea, penicillium italicum, phytophthora citrophthora, and rhizopus stolonifer. essential oils were obtained from hyssopus officinalis, lavandula angustifolia, majorana hortensis, melissa officinalis, ocimum basilicum, origanum vulgare, salvia officinalis, and thymus vulgaris (family lamiaceae), verbena officinalis (family ...201020874226
genotoxicity of lavender oil, linalyl acetate, and linalool on human lymphocytes in vitro.the potential genotoxicity of lavender essential oil and its major components, linalool, and linalyl acetate, was evaluated in vitro by the micronucleus test on peripheral human lymphocytes. in the range of non-toxic concentrations (0.5-100 μg/ml), linalyl acetate increased the frequency of micronuclei significantly and in concentration-dependent manner; lavender oil did so only at the highest concentration tested, whereas linalool was devoid of genotoxicity. none of the tested substances led to ...201120839219
in vitro and in vivo antifungal activities of the essential oils of various plants against tomato grey mould disease agent botrytis cinerea.the aim of this study was to find an alternative to synthetic fungicides currently used in the control of devastating fungal pathogen botrytis cinerea, the causal agent of grey mould disease of tomato. antifungal activities of essential oils obtained from aerial parts of aromatic plants, which belong to the lamiacea family such as origanum (origanum syriacum l. var. bevanii), lavender (lavandula stoechas l. var. stoechas) and rosemary (rosmarinus officinalis l.), were investigated against b. cin ...201020826038
[effects of oral care with essential oil on improvement in oral health status of hospice patients].this study was done to examine the effects of oral care with essential oil in improving the oral health status of hospice patients with terminal cancer.201020820114
a randomised, assessor blind, parallel group comparative efficacy trial of three products for the treatment of head lice in children--melaleuca oil and lavender oil, pyrethrins and piperonyl butoxide, and a "suffocation" product.there are many different types of pediculicides available otc in australia. in this study we compare the efficacy and safety of three topical pediculicides: a pediculicide containing melaleuca oil (tea tree oil) and lavender oil (tto/lo); a head lice "suffocation" product; and a product containing pyrethrins and piperonyl butoxide (p/pb).201020727129
physical properties of gum karaya-starch-essential oil patches.essential oils are used in foods, cosmetics, and pharmaceuticals. despite the recent marketing of novel essential-oil-containing patches, there is no information on their production, constituents, or physical properties. the objectives of this study were to produce essential-oil patches and characterize their physical properties. the essential oil of lavandula angustifolia (lavender) was included at concentrations of 2.5% to 10% in patches manufactured from the exudate gum karaya, propylene glyc ...201020711695
essential oil composition and larvicidal activity of six mediterranean aromatic plants against the mosquito aedes albopictus (diptera: culicidae).laboratory bioassays on insecticidal activity of essential oils (eos) extracted from six mediterranean plants (achillea millefolium, lavandula angustifolia, helichrysum italicum, foeniculum vulgare, myrtus communis, and rosmarinus officinalis) were carried out against the larvae of the culicidae mosquito aedes albopictus. the chemical composition of the six eos was also investigated. results from applications showed that all tested oils had insecticidal activity, with differences in mortality ra ...201020697909
biodegradable gelatin-chitosan films incorporated with essential oils as antimicrobial agents for fish preservation.essential oils of clove (syzygium aromaticum l.), fennel (foeniculum vulgare miller), cypress (cupressus sempervirens l.), lavender (lavandula angustifolia), thyme (thymus vulgaris l.), herb-of-the-cross (verbena officinalis l.), pine (pinus sylvestris) and rosemary (rosmarinus officinalis) were tested for their antimicrobial activity on 18 genera of bacteria, which included some important food pathogen and spoilage bacteria. clove essential oil showed the highest inhibitory effect, followed by ...201020688230
biosynthesis and therapeutic properties of lavandula essential oil constituents.lavenders and their essential oils have been used in alternative medicine for several centuries. the volatile compounds that comprise lavender essential oils, including linalool and linalyl acetate, have demonstrative therapeutic properties, and the relative abundance of these metabolites is greatly influenced by the genetics and environment of the developing plants. with the rapid progress of molecular biology and the genomic sciences, our understanding of essential oil biosynthesis has greatly ...201120665367
activities of ten essential oils towards propionibacterium acnes and pc-3, a-549 and mcf-7 cancer cells.ten essential oils, namely, mint (mentha spicata l., lamiaceae), ginger (zingiber officinale rosc., zingiberaceae), lemon (citrus limon burm.f., rutaceae), grapefruit (citrus paradisi macf., rutaceae), jasmine (jasminum grandiflora l., oleaceae), lavender (mill., lamiaceae), chamomile (matricaria chamomilla l., compositae), thyme (thymus vulgaris l., lamiaceae), rose (rosa damascena mill., rosaceae) and cinnamon (cinnamomum zeylanicum n. lauraceae) were tested for their antibacterial activities ...201020657472
phytotoxic activities of mediterranean essential oils.twelve essential oils from mediterranean aromatic plants were tested for their phytotoxic activity, at different doses, against the germination and the initial radicle growth of seeds of raphanus sativus, lactuca sativa and lepidium sativum. the essential oils were obtained from hyssopus officinalis, lavandula angustifolia, majorana hortensis, melissa officinalis, ocimum basilicum, origanum vulgare, salvia officinalis and thymus vulgaris (lamiaceae), verbena officinalis (verbenaceae), pimpinella ...201020657443
the study protocol of a blinded randomised-controlled cross-over trial of lavender oil as a treatment of behavioural symptoms in dementia.the agitated behaviours that accompany dementia (e.g. pacing, aggression, calling out) are stressful to both nursing home residents and their carers and are difficult to treat. increasingly more attention is being paid to alternative interventions that are associated with fewer risks than pharmacology. lavandula angustifolia (lavender) has been thought, for centuries, to have soothing properties, but the existing evidence is limited and shows mixed results. the aim of the current study is to tes ...201020649945
a systematic review on the anxiolytic effects of aromatherapy on rodents under experimentally induced anxiety models.we reviewed studies from 1999 to 2009 on anxiolytic effects of different essential oils toward rodents in anxiety-related behavioral models.201020614803
growth inhibition of aspergillus ochraceus zmpbf 318 and penicillium expansum zmpbf 565 by four essential oils.fungi produce a large variety of extracellular proteins, organic acids, and other metabolites and can adapt to several environmental conditions. mycotoxin-producing moulds of the genera aspergillus and penicillium are common food contaminants. one of the natural ways to protect food from mould contamination is to use essential oils. in this study, we evaluated the effect of essential oils of cinnamon, lavender, rosemary, and sage at 1 % (v/v) concentration in yeast media inoculated with spores ( ...201020587393
lavender, tea tree and lemon oils as antimicrobials in washing liquids and soft body balms.the aim of this study was to evaluate the antimicrobial activity of commercial essential oils: lavender, tea tree and lemon, antimicrobials in washing liquid and o/w soft body balm. the inhibition efficacy of essential oils in washing liquid (1% alone or in mixtures), in soft body balm (0.5% alone), as well as combined with the synthetic preservative dmdm hydantoin and 3-iodo-2-propynyl butyl carbamate mixture (0.1 and 0.3%), was tested against s. aureus atcc 6538, p. aeruginosa atcc 9027, candi ...201120572887
silexan, an orally administered lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder: a randomized, double-blind, placebo controlled trial.this study was performed to investigate the anxiolytic efficacy of silexan, a new oral lavender oil capsule preparation, in comparison to placebo in primary care. in 27 general and psychiatric practices 221 adults suffering from anxiety disorder not otherwise specified (diagnostic and statistical manual of mental disorders-iv 300.00 or international statistical classification of diseases and related health problems, tenth revision f41.9) were randomized to 80 mg/day of a defined, orally administ ...201020512042
antidepressant-like effect of salvia sclarea is explained by modulation of dopamine activities in rats.the purpose of the present study was to screen aromatic essential oils that have antidepressant effects to identify the regulatory mechanisms of selected essential oils.201020441789
lavandula angustifolia essential oil as a novel and promising natural candidate for tick (rhipicephalus (boophilus) annulatus) control.lavandula angustifolia is a well known herbal medicine with a variety of useful properties, including its acaricidal effect. this experiment was carried out to study the bioacaricidal activity of l. angustifolia essential oil (eo) against engorged rhipicephalus (boophilus) annulatus (acari; ixodidae) females. for this purpose six serial concentrations (0.5, 1.0, 2.0, 4.0, 6.0 and 8.0% w/v) of l. angustifolia eo were used. there was considerable mortality in concentrations more than 4.0% although ...201020433836
whole-genome snp association in the horse: identification of a deletion in myosin va responsible for lavender foal syndrome.lavender foal syndrome (lfs) is a lethal inherited disease of horses with a suspected autosomal recessive mode of inheritance. lfs has been primarily diagnosed in a subgroup of the arabian breed, the egyptian arabian horse. the condition is characterized by multiple neurological abnormalities and a dilute coat color. candidate genes based on comparative phenotypes in mice and humans include the ras-associated protein rab27a (rab27a) and myosin va (myo5a). here we report mapping of the locus resp ...201020419149
antibacterial activity of essential oils from palmarosa, evening primrose, lavender and tuberose.essential oils extracted from flower petals of palmarosa (cymbopogon martini), evening primrose (primula rosea), lavender (lavandula angustifolia) and tuberose (polianthus tuberosa) were tested for their antibacterial activities against gram-positive and gram-negative bacteria. different concentrations of each essential oil ranging from 10-100% were tested. both gram-positive and gram-negative bacteria were found susceptible to the studied flower essential oils. with increase in concentration of ...200920336210
chemical composition and in vitro antimicrobial activity of essential oil of melissa officinalis l. from romania.melissa officinalis l. (lemon balm) is used in traditional medicine to treat insomnia, anxiety, gastric conditions, psychiatric conditions, migraines, hypertension and bronchial conditions. natural essential oils (mixtures of fragrant chemical) obtained from various parts of plants are efficient active antimicrobial agents. the widespread use of antimicrobial agents selects resistant bacterial strains, which seriously compromise the effectiveness of antibiotic treatment. the use of herbal medici ...200820201279
serum and plasma determination of angiogenic and anti-angiogenic factors yield different results: the need for standardization in clinical practice.the importance of an anti-angiogenic state as a mechanism of disease in preeclampsia is now recognized. assays for the determination of concentrations of soluble vascular endothelial growth factor receptor (svegfr)-1, svegfr-2, placental growth factor (plgf) and soluble endoglin (seng) have been developed for research and clinical laboratories. a key question is whether these factors should be measured in plasma or serum. the purpose of this study was to determine if there are differences in the ...201020158394
comparative study of the chemical composition and antioxidant activity of six essential oils and their components.the antioxidant activities and the determined major components of six popular and commercially available herb essential oils, including lavender (lavendular angustifolia), peppermint (mentha piperita), rosemary (rosmarius officinalis), lemon (citrus limon), grapefruit (citrus paradise), and frankincense (boswellia carteri), were compared. the essential oils were analysed by gc-ms and their antioxidant activities were determined by testing free radical-scavenging capacity and lipid peroxidation i ...201020077307
a genomics resource for investigating regulation of essential oil production in lavandula angustifolia.we are developing lavandula angustifolia (lavender) as a model system for investigating molecular regulation of essential oil (a mixture of mono- and sesquiterpenes) production in plants. as an initial step toward building the necessary 'genomics toolbox' for this species, we constructed two cdna libraries from lavender leaves and flowers, and obtained sequence information for 14,213 high-quality expressed sequence tags (ests). based on homology to sequences present in genbank, our est collectio ...201020043174
essential oils in the treatment of intestinal dysbiosis: a preliminary in vitro study.dysbiosis is associated with a number of gastrointestinal and systemic disorders. there is a need for selectively acting antimicrobial agents capable of inhibiting the growth of potentially pathogenic microorganisms, or those found to be out of balance, while not negatively impacting the bulk gastrointestinal tract microflora.200920030464
differential accumulation of volatile terpene and terpene synthase mrnas during lavender (lavandula angustifolia and l. x intermedia) inflorescence development.despite the commercial importance of lavandula angustifolia mill. and l. x intermedia emeric ex loisel floral essential oils (eos), no information is currently available on potential changes in individual volatile organic compound (voc) content during inflorescence development. calyces were found to be the main sites of voc accumulation. the 20 most abundant vocs could be separated into three sub-groups according to their patterns of change in concentration the three groups of vocs sequentially ...201020002329
[a review on pharmic effect of chicory research and development].chicory (cichorium intybus l) is a bushy perennial herb with blue, lavender, or occasionally white flowers. it grows as a wild plant on roadsides in its native europe, and in north america, where it has become naturalized. common chicory is also known as blue sailors, succory, and coffeeweed. chicory contains saccharides, organic acid, alkaloid, triterpenes, sesquiterpenes, coumarins, and so on. it has a function of lowering the blood glucose and lipid, decreasing uric acid, and hepatoprotection ...200919943500
cristispira in north american shellfish. a note on a spirillum found in oysters.ten varieties of north american shellfish were examined for the occurrence of cristispira in their styles. a cristispira was found in various numbers in ostrea virginiana, venus mercenaria, and modiola modiolus, but none in ensis americana, mya arenaria, mactra solidissima, pecten irradians, mytilus edulis, fulgur canaliculatus, or nassa obsoleta. of 298 oysters, only 128 showed the crystalline styles, in which cristispiras were present in 99. active cristispiras were found in 59 styles only and ...192119868559
essential oils and anxiolytic aromatherapy.a number of essential oils are currently in use as aromatherapy agents to relieve anxiety, stress, and depression. popular anxiolytic oils include lavender (lavandula angustifolia), rose (rosa damascena), orange (citrus sinensis), bergamot (citrus aurantium), lemon (citrus limon), sandalwood (santalum album), clary sage (salvia sclarea), roman chamomile (anthemis nobilis), and rose-scented geranium (pelargonium spp.). this review discusses the chemical constituents and cns effects of these aroma ...200919831048
inhibition of quorum-sensing signals by essential oils.the role of quorum sensing (qs) is well known in microbial pathogenicity and antibiotic resistance. qs is responsible for motility, swarming, and biofilm production based on the signal molecules, e.g., acylated homoserine lactones (ahls) produced by micro-organisms above certain population density. the inhibition of qs may reduce pathogenicity, antibiotic resistance and biofilm formation in systemic and local infections. the homoserine lactones and other transmitters contribute to antibiotic res ...201019827025
acaricidal and insecticidal activity of essential oils on varroa destructor (acari: varroidae) and apis mellifera (hymenoptera: apidae).varroa destructor is an external parasitic mite that is a serious pest of honeybees and has caused severe losses of colonies worldwide. one of the feasible alternative treatments being used for their control is essential oils. the aim of this work was to evaluate the bioactivity of some essential oils on v. destructor and apis mellifera in relation with their chemical composition and physicochemical properties. lavender, lavendin and laurel essential oils showed linalool as main compound in thei ...200919795133
lavender as a source of novel plant compounds for the development of a natural herbicide.in a previous study, lavender (lavandula spp.) was found to be highly phytotoxic towards annual ryegrass (lolium rigidum, arg), a major weed of winter wheat crops in australia. this research aimed to further explore this relationship and determine the chemical(s) responsible for the observed effect. in bioassay, it was determined that the stem and leaf extract of l. x intermedia cv. grosso ranked highest and had the potential to reduce significantly the root growth of several plant species. an e ...200919787403
effect of commercially available plant-derived essential oil products on arthropod pests.plant-derived essential oil products, in general, are considered minimum-risk pesticides and are exempt from environmental protection agency registration under section 25(b) of the federal insecticide fungicide and rodenticide act. however, many of the plant-derived essential products available to consumers (homeowners) have not been judiciously evaluated for both efficacy and plant safety. in fact, numerous plant-derived essential oil products labeled for control of arthropod pests have not bee ...200919736770
mercury uptake and distribution in lavandula stoechas plants grown in soil from almadén mining district (spain).this work studies mercury root uptake by lavandula stoechas var. kew red (lavender) and the distribution of this metal through the plant under greenhouse conditions along three consecutive seasons. mercury concentration in plant tissues and in the different products obtained from lavender plants (essential oil, toilet water and in lavender tea) was assessed in order to evaluate the possible cultivation of lavender as a profitable alternative land use to mercury mining in the almadén area once th ...200919699252
effects of ultraviolet radiation on the kinetics of in vitro percutaneous absorption of lavender oil.the purpose of the present study is to investigate the influence of ultraviolet radiation on the rat skin absorption of lavender essential oil. the pure oil was extracted from lavandula angustifolia by steam distillation. the chemical composition of lavender oil showed that terpenes are major compounds. in vitro, the essential oil was applied onto the rat skin. the amount of the compounds was determined using gas chromatography. similarly, the amount of these compounds was analyzed for the skin ...200919683042
physico-chemical change and heat stability of extra virgin olive oils flavoured by selected tunisian aromatic plants.objectives of this work were studying physico-chemical change and heat stability of olive oils flavoured by selected tunisian aromatic plants. flavoured olive oils were prepared by maceration of fresh plant materials (rosemary, lavender, sage, menthe, basil, lemon and thyme) with olive oil at a 5% w/w level for 15 days. a sensorial evaluation was applied to select more appreciate flavoured olive oils by consumers. an oxidative procedure was applied to test the stability of selected flavoured oli ...200919635520
inhibition of quorum sensing regulated bacterial functions by plant essential oils with special reference to clove oil.to evaluate quorum sensing (qs) inhibitory activity of plant essential oils using strains of chromobacterium violaceum (cv12472 and cvo26) and pseudomonas aeruginosa (pao1).200919627477
intraplantar injection of bergamot essential oil into the mouse hindpaw: effects on capsaicin-induced nociceptive behaviors.despite the increasing use of aromatherapy oils, there have not been many studies exploring the biological activities of bergamot (citrus bergamia, risso) essential oil (beo). recently, we have investigated the effects of beo injected into the plantar surface of the hindpaw in the capsaicin test in mice. the intraplantar injection of capsaicin produced an intense and short-lived licking/biting response toward the injected hindpaw. the capsaicin-induced nociceptive response was reduced significan ...200919607974
effect of lavender oil on motor function and dopamine receptor expression in the olfactory bulb of mice.although treatment with the essential oil of lavender induces neuroemotional changes, there is a lack of data regarding its specific effects on neurotransduction, especially dopaminergic neurotransduction. we investigated the relationship between altered motor activity and changes in the expression of dopamine receptors (dr), particularly the receptor subtypes d2 and d3, in lavender oil-treated mice.200919560529
comparison of bacteriostatic and bactericidal activity of 13 essential oils against strains with varying sensitivity to antibiotics.to compare the bacteriostatic and bactericidal activity of 13 chemotyped essential oils (eo) on 65 bacteria with varying sensitivity to antibiotics.200819552780
antimicrobial activity of lavender, tea tree and lemon oils in cosmetic preservative systems.the aim of the study was to verify the antimicrobial activity of commercial essential oils: lavender, tea tree and lemon as the components of a preservative system in oil in water body milks.200919508298
plumage colour mutations and melanins in the feathers of the japanese quail: a first comparison.the absorbance of melanin content from dorsal feathers was compared between wild-type japanese quail and nine other quail plumage colours determined by single mutations in one of seven genes: extended brown (mc1r), yellow (asip), silver (mitf), lavender (mlph), roux (tyrp1), imperfect albinism (slc45a2) and rusty. as compared with wild-type quail, all mutations but extended brown decreased total melanins. the largest decrease was observed in quail with one of the dilution mutations at tyrp1, mlp ...200919496774
evaluation of the effect of topical application of lavender oil on autonomic nerve activity in dogs.to investigate the effect of topical application of undiluted lavender oil on sympathovagal activity in dogs.200919496667
the battle against multi-resistant strains: renaissance of antimicrobial essential oils as a promising force to fight hospital-acquired infections.hospital-acquired infections and antibiotic-resistant bacteria continue to be major health concerns worldwide. particularly problematic is methicillin-resistant staphylococcus aureus (mrsa) and its ability to cause severe soft tissue, bone or implant infections. first used by the australian aborigines, tea tree oil and eucalyptus oil (and several other essential oils) have each demonstrated promising efficacy against several bacteria and have been used clinically against multi-resistant strains. ...200919473851
anti-biofilm properties of satureja hortensis l. essential oil against periodontal pathogens.essential oils of several plants are widely used in ethnomedicine for their antimicrobial and anti-inflammatory properties. however, very limited data exist on their use in connection to periodontal diseases. the aim of the present study was to investigate the bacterial growth inhibiting and anti-biofilm effects of satureja hortensis l. (summer savory), salvia fruticosa m. (sage), lavandula stoechas l. (lavender), myrtus communis l., and juniperus communis l. (juniper) essential oils. chemical c ...200919285147
the antimicrobial activity of high-necrodane and other lavender oils on methicillin-sensitive and -resistant staphylococcus aureus (mssa and mrsa).the objective of this study was to compare the antimicrobial efficacy of several lavender oils, used singly and in combination, on methicillin-sensitive and methicillin-resistant staphylococcus aureus (mssa and mrsa).200919249919
lavandula angustifolia miller: english lavender.folk and traditional therapeutic use of the essential oil of english lavender for pain, infection, relaxation, and sedation dates back centuries. current research focusing on the inherent synergism of lavandula angustifolia miller demonstrates great potential for future applications. today's investigations may provide the key to eradicating degenerative inflammatory disease, infectious disease, and carcinogenesis.200919104276
rosmarinic acid and antioxidant enzyme activities in lavandula vera mm cell suspension culture: a comparative study.the growth and intracellular protein content of lavender (lavandula vera mm) cell suspension culture was followed along with some antioxidant defense system members-non-enzymatic (rosmarinic acid) and enzymatic [superoxide dismutase (ec 1.15.1.1) and catalase (ec 1.11.1.6)]. it was found that the media content and the cultivation mode strongly influenced the production of plant defense compounds as well as the ratio between non-enzymatic and enzymatic ones. the bioreactor culture contains about ...200919050834
pharmacological profile of essential oils derived from lavandula angustifolia and melissa officinalis with anti-agitation properties: focus on ligand-gated channels.both melissa officinalis (mo) and lavandula angustifolia (la) essential oils have putative anti-agitation properties in humans, indicating common components with a depressant action in the central nervous system. a dual radioligand binding and electrophysiological study, focusing on a range of ligand-gated ion channels, was performed with a chemically validated essential oil derived from la, which has shown clinical benefit in treating agitation. la inhibited [35s] tbps binding to the rat forebr ...200818957173
improved microwave steam distillation apparatus for isolation of essential oils. comparison with conventional steam distillation.steam distillation (sd) is routinely used by analysts for the isolation of essential oils from herbs, flowers and spices prior to gas chromatographic analysis. in this work, a new process design and operation for an improved microwave steam distillation (msd) of essential oils from aromatic natural products was developed. to demonstrate its feasibility, msd was compared with the conventional technique, sd, for the analysis of volatile compounds from dry lavender flowers (lavandula angustifolia m ...200818849039
inhaled linalool-induced sedation in mice.linalool is a monoterpene often found as a major component of essential oils obtained from aromatic plant species, many of which are used in traditional medical systems as hypno-sedatives. psychopharmacological evaluations of linalool (i.p. and i.c.v.) revealed marked sedative and anticonvulsant central effects in various mouse models. considering this profile and alleged effects of inhaled lavender essential oil, the purpose of this study was to examine the sedative effects of inhaled linalool ...200918824339
lavender oil lacks natural protection against autoxidation, forming strong contact allergens on air exposure.lavender oil is an essential oil frequently used as a fragrance ingredient and in traditional herbal medicine. we have previously studied the effect of air oxidation on the skin sensitizing potency of the monoterpenes linalyl acetate, linalool and beta-caryophyllene, the main constituents of lavender oil.200818759894
blue tits (cyanistes caeruleus) respond to an experimental change in the aromatic plant odour composition of their nest.although the use of olfaction by birds is now widely recognised, the olfactory abilities of passerine birds remain poorly explored, for historical reasons. several studies however suggest that passerines can perceive volatile compounds in several biologically relevant contexts. in corsica, recent findings suggest that cavity-nesting blue tits may use volatile compounds in the context of nest building and maintenance. although they build their nests mainly from moss, female blue tits also frequen ...200818692552
the qualitative analysis of ethanol extracts of herbal raw materials by method of high pressure liquid chromatography.the article describes the qualitative analysis of ethanol extracts from st. john's wort, cinnamon bark, rosemary leaves, lavender flowers, and ginger rhizomes, and the extract of their mixture using the method of high pressure liquid chromatography in order to identify flavonoids. the aim of the study was to identify the amounts of rutin, hyperoside, quercetin, and other flavonoids in the multi-component extract as well as in the control extracts of its compositional parts using the method of hi ...200718536158
day-night difference in thermoregulatory responses to olfactory stimulation.previously, we observed that olfactory stimulation with scent of grapefruit oil (sgfo) or scent of lavender oil (slvo) affected, elevated or lowered brown adipose tissue temperature (bat-t) in conscious mice, respectively. in the present study, to test the day-night difference in the actions of olfactory stimulations, we examined the responses of bat-t and body temperature (bt) measured as the abdominal temperature to sgfo or slvo during day-time at 14:00 and night-time at 2:00 in conscious rats ...200818514405
expression of spearmint limonene synthase in transgenic spike lavender results in an altered monoterpene composition in developing leaves.we generated transgenic spike lavender (lavandula latifolia) plants constitutively expressing the limonene synthase (ls) gene from spearmint (mentha spicata), encoding the ls enzyme that catalyzes the synthesis of limonene from geranyl diphosphate. overexpression of the ls transgene did not consistently affect monoterpene profile in pooled leaves or flowers from transgenic t(0) plants. analyses from cohorts of leaves sampled at different developmental stages showed that essential oil accumulatio ...200818514005
oral malodor reduction by a palatal mucoadhesive tablet containing herbal formulation.the aim of the present study was to test the effect of a palatal mucoadhesive tablet containing an herbal formulation on oral malodor production and volatile sulfide compound (vsc) levels, and to evaluate its antimicrobial activity.200818468761
influence of essential and fatty oils on ciliary beat frequency of human nasal epithelial cells.in alternative and complementary medicine, the use of essential and fatty oils has become more and more popular. in addition to conventional medical therapies, self-medication is showing increasing popularity, using agents with unclear compounds and poorly controlled dosages. among other disorders, these alternative treatments are used in bronchitis and rhinitis, including some topical applications. thus, the influence on ciliated epithelia should be evaluated, because a disturbance of the cilia ...200818416967
comparative chemometric analyses of geographic origins and compositions of lavandin var. grosso essential oils by mid infrared spectroscopy and gas chromatography.lavandin, a sterile hybrid of lavandula angustifolia p. mill. x lavandula latifolia (l.f.) medikus (lamiaceae) is a plant widely cultivated for essential oil production in the south of france. chemometric treatment by mid-infrared (mid-ir) spectroscopy data was assessed for the differentiation of grosso lavandin essential oils of controlled area (gleoca) and results were compared to those obtained by gas chromatography for mid-ir short time technique validation. the quantification of the main 13 ...200818374699
lack of prolonged activity of lavender essential oils as acaricides against the poultry red mite (dermanyssusgallinae) under laboratory conditions.managing the poultry red mite, dermanyssusgallinae (de geer) by conventional means (i.e., synthetic acaricides) has become increasingly problematic. as a possible alternative, research has identified several plant essential oils that are toxic to d. gallinae. however, essential oils are highly volatile and any acaricidal effect they exert could be short-lived in practice. this study investigated the short-lived toxicity of six lavender essential oils to d. gallinae. in sealed petri-dishes, mites ...200818348893
investigation of the anxiolytic effects of linalool, a lavender extract, in the male sprague-dawley rat.the purpose of our study was to investigate the anxiolytic effects of linalool and its potential interaction with the gabaa receptor in sprague-dawley rats. lavender has been used traditionally as an herbal remedy in the treatment of many medical conditions, including anxiety. linalool is a major component of the essential oil of lavender. forty-four rats were divided into 4 groups: control, linalool, midazolam (positive control), and flumazenil and linalool. the behavioral and the neurohormonal ...200818323320
the effect of essential oils on work-related stress in intensive care unit nurses.this small pilot study evaluated the effect of a topical application of the essential oils lavandula angustifolia and salvia sclaria on work-related stress of nurses in an icu setting. results demonstrated decreased perception of stress level in the intervention group during three 12-hour worked shifts.200818317288
analysis of the volatile compounds of flowers and essential oils from lavandula angustifolia cultivated in northeastern italy by headspace solid-phase microextraction coupled to gas chromatography-mass spectrometry.headspace solid-phase microextraction (hs-spme) coupled to gas chromatography and mass spectrometry using the divinyl/carboxen/polydimethylsiloxane (dvb-car-pdms) fibre was applied for the analysis of aroma profiles of lavandula angustifolia l. flowers and the corresponding essential oils. the optimal sampling time was determined by studying the equilibrium time profile of the major volatile compounds for the lavender flowers (50 min) and the essential oil (20 min). comparative analysis of l. an ...200818247262
determination of the antioxidant capacity of culinary herbs subjected to various cooking and storage processes using the abts(*+) radical cation assay.culinary herbs have the potential to be a significant source of antioxidants in the diet. however, many culinary herbs are cooked or undergo some other form of processing before they are consumed as part of a meal and such factors may affect their significance as a source of dietary antioxidants. thus, the impact of cooking (simmering, microwaving, stewing, stir frying and grilling) and storage (vinegar maceration, cold maceration and freezing) on the antioxidant capacity of common culinary herb ...200818224444
effects of olfactory stimulations with scents of grapefruit and lavender oils on renal sympathetic nerve and blood pressure in clock mutant mice.previously, we observed that in mice, olfactory stimulation with scent of grapefruit oil elevates renal sympathetic nerve activity and blood pressure. in contrast, olfactory stimulation with scent of lavender oil has opposite effects in mice. moreover, electrolytic lesions of the mouse hypothalamic suprachiasmatic nucleus eliminated changes in renal sympathetic nerve activity and blood pressure induced by either scent of grapefruit oil or scent of lavender oil. here, we show that grapefruit oil- ...200818201946
a single point-mutation within the melanophilin gene causes the lavender plumage colour dilution phenotype in the chicken.the lavender phenotype in the chicken causes the dilution of both black (eumelanin) and red/brown (phaeomelanin) pigments. defects in three genes involved in intracellular melanosomal transport, previously described in mammals, give rise to similar diluted pigmentation phenotypes as those seen in lavender chickens.200818197963
quantification of free coumarin and its liberation from glucosylated precursors by stable isotope dilution assays based on liquid chromatography-tandem mass spectrometric detection.a stable isotope dilution assay for the quantification of free coumarin and glucosylated coumarin precursors has been developed using [13c2]-coumarin as the internal standard. the doubly labeled coumarin was synthesized by reacting [13c2]-acetic anhydride with salicylic aldehyde and characterized by means of mass spectrometry and nuclear magnetic resonance (nmr) experiments. the specifity of liquid chromatography-tandem mass spectrometry enabled unequivocal determination and sensitive quantitati ...200818197622
novel lipophilic tracking dyes for monitoring cell proliferation.the advent of contemporary digital instrumentation has enhanced both the potential and the complexity of flow cytometric experiments, allowing for the detailed dissection of immune cell subsets and their functions. the use of cell tracking labels such as pkh26 and cfse has been important in observing such cellular functions, but their visible emission characteristics have limited the design of such analyses. as the demand for multiparametric flow cytometry intensifies, it will become increasingl ...200718161533
autoxidation of linalyl acetate, the main component of lavender oil, creates potent contact allergens.fragrances are among the most common causes of allergic contact dermatitis. we have in previous studies shown that linalool, present in lavender oil, autoxidizes on air exposure, forming allergenic oxidation products. oxidized linalool was found to be a frequent cause of contact allergy in a patch test study on consecutive dermatitis patients. linalyl acetate, the main component of lavender oil is commonly used as a fragrance chemical in scented products. because of structural similarities, lina ...200818154552
the influence of essential oils on the process of wound healing: a review of the current evidence.this paper reports on a literature review of evidence on the influence of essential oils on wound healing and their potential application in clinical practice. it focuses mainly on tea tree, lavender, chamomile, thyme and ocimum oils.200717722522
up-regulation of an n-terminal truncated 3-hydroxy-3-methylglutaryl coa reductase enhances production of essential oils and sterols in transgenic lavandula latifolia.spike lavender (lavandula latifolia) essential oil is widely used in the perfume, cosmetic, flavouring and pharmaceutical industries. thus, modifications of yield and composition of this essential oil by genetic engineering should have important scientific and commercial applications. we generated transgenic spike lavender plants expressing the arabidopsis thaliana hmg1 cdna, encoding the catalytic domain of 3-hydroxy-3-methylglutaryl coa reductase (hmgr1s), a key enzyme of the mevalonic acid (m ...200717714440
the effect of gender and ethnicity on children's attitudes and preferences for essential oils: a pilot study.aromatherapy is frequently recommended for children but children's preferences for specific essential oils are not well documented.201617681258
cloning and functional characterization of three terpene synthases from lavender (lavandula angustifolia).the essential oil of lavender (lavandula angustifolia) is mainly composed of mono- and sesquiterpenes. using a homology-based pcr strategy, two monoterpene synthases (lalims and lalins) and one sesquiterpene synthase (labers) were cloned from lavender leaves and flowers. lalims catalyzed the formation of (r)-(+)-limonene, terpinolene, (1r,5s)-(+)-camphene, (1r,5r)-(+)-alpha-pinene, beta-myrcene and traces of alpha-phellandrene. the proportions of these products changed significantly when mn(2+) ...200717662687
an investigation and comparison of the bioactivity of selected essential oils on human lice and house dust mites.the insecticidal potency of some essential oils suggests that they may find an application in the control of house dust mites, but current in vitro assays for mites do not appear to give consistent results. a simple, novel, mite chamber assay was therefore developed to carry out testing. different species of insects are susceptible to different essential oil components, so we compared the relative acaricidal and pediculicidal activity of three essential oils: tea tree, lavender and lemon, becaus ...200717662541
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