Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [cloning and sequencing of adenovirus type 7 vaccine strain 76.5-87 mu fragment]. | adenovirus 7(ad7) vaccine strain has been used more than 30 years in us army recruits for prevention of ad7 infection and has been proven to be safe and effective. recent years more attention has been paid to exploring the possibilities of using it for gene therapy or making recombinant vaccine. in order to construct adenovirus 7 vector, ad 7 vaccine strain 76.5-87 mu fragment was cloned and sequenced. the fragment contains 3,557 bp which encodes 6 proteins of e3 region, namely 12.1 kd, 19.2 kd, ... | 1998 | 12526316 |
| [sequence analysis of ad7 vaccine strain 87 mu-97.4 mu fragment]. | adenovirus 7 vaccine strain(ad7v) possesses potentiality to be used as a vector for producing recombinant vaccine. in order to construct ad7 vector, the nucleotide sequence of a 3698 bp fragment(87 to 97.4 mu) of the virus dna was analysed. the fragment encodes three orfs namely, one orf of early region 4(e4), one orf of early region 3 and one orf of fiber protein. the predicted amino acids of three orfs(orf 8.1 kd, 42.8 kd and 10.3 kd) share 33%, 43% and 44% homology with ad2 e4 corresponding r ... | 1998 | 12515181 |
| biology of ovine adenovirus infection of nonpermissive cells. | nonhuman adenoviruses, including those of the genus atadenovirus, have the potential to serve as vectors for vaccine and gene therapy applications in humans, since they are resistant to preexisting immunity induced by human adenoviruses in the majority of the population. in this study, we elucidate the outcome of infection by ovine adenovirus type 7 isolate 287 (oadv) of several nonovine cell types. we show here that oadv infects a wide range of nonovine cells but is unable to complete its repli ... | 2002 | 12368331 |
| genetic organization and sequence analysis of pviii, fiber and early region 4 of bovine adenovirus type 7. | the dna sequence of 8,810 nucleotides at the right end of bovine adenovirus type 7 (bav7) genome was determined and compared with similar regions of other adenoviruses. this genomic region of bav7 consists of sequences encoding partial 33k, pviii, fiber, putative early region 4 (e4) proteins and other unassigned proteins. however, bav7 e3 region is not present in the expected location between pviii and fiber as bav7 intergenic region between pviii and fiber genes is only 183 nucleotides. the pre ... | 2002 | 12206309 |
| adenovirus type 7 associated with severe and fatal acute lower respiratory infections in argentine children. | adenoviruses are the second most prevalent cause of acute lower respiratory infection of viral origin in children under four years of age in buenos aires, argentina. the purpose of this study was to analyze the clinical features and outcome of acute lower respiratory infection associated with different adenovirus genotypes in children. | 2002 | 12184818 |
| evidence for the presence of half-cystine residues in the capsid of adenovirus type 7. | 1970 | 11947446 | |
| molecular epidemiology of adenovirus type 7 in the united states, 1966-2000. | genetic variation among 166 isolates of human adenovirus 7 (ad7) obtained from 1966 to 2000 from the united states and eastern ontario, canada, was determined by genome restriction analysis. most (65%) isolates were identified as ad7b. two genome types previously undocumented in north america were also identified: ad7d2 (28%), which first appeared in 1993 and was later identified throughout the midwest and northeast of the united states and in canada; and ad7h (2%), which was identified only in ... | 2002 | 11927024 |
| molecular and epidemiological analyses of human adenovirus type 7 strains isolated from the 1995 nationwide outbreak in japan. | the adenovirus type 7 (ad7) isolates from the 1995 nationwide outbreak in japan were genetically and seroepidemiologically analyzed in comparison with japanese ad7 strains isolated before 1995 to determine their genome type and to speculate on their origin and causative factors of the outbreak. twenty-six ad7 isolates from the outbreak were identified by restriction enzyme analysis as the ad7d2 genome type, while 22 ad7 strains sporadically isolated in japan before 1995 were identified as ad7d. ... | 2002 | 11773107 |
| [establishment and characterization of a cell line derived from human ovarian mucinous cystadenocarcinoma]. | to establish a cell line of human ovarian cancer, and study its characterization. | 2001 | 11718030 |
| fatal adenovirus type 7b infection in a child with smith-lemli-opitz syndrome. | adenovirus type 7 causes worldwide respiratory tract infections, mainly in children. severe systemic infections can occur, especially in immunocompromised patients and in patients with underlying chronic diseases. this report describes the first case of a fatal disseminated adenovirus type 7 infection in a child with smith-lemli-opitz syndrome, a rare autosomal recessive disorder due to a primary enzymatic defect in cholesterol metabolism. nasopharyngeal secretions and autopsy specimens includin ... | 2001 | 11505445 |
| adenovirus type 7 induces interleukin-8 production via activation of extracellular regulated kinase 1/2. | infection with adenovirus serotype 7 (ad7) frequently causes lower respiratory pneumonia and is associated with severe lung inflammation and neutrophil infiltration. earlier studies indicated release of proinflammatory cytokines, specifically interleukin-8 (il-8), by pulmonary epithelial cells following infection by ad7. however, the mechanism of il-8 induction by ad7 is unclear. we have explored the role of the ras/raf/mek/erk pathway in the ad7-associated induction of il-8 using a model system ... | 2001 | 11413312 |
| a modified rapid method of nucleic acid isolation from suspension of matured virus: applied in restriction analysis of dna from an adenovirus prototype strain and a patient isolate. | this report describes a method for the isolation of nucleic acid from a suspension of matured virus. nucleic acid (dna) was isolated from a prototype strain of adenovirus type 7 and a clinical isolate of adenovirus type 7. instead of the usual method of ultracentifugation, a filtration method was applied to concentrate the virus rapidly and nucleic acid was then isolated by a standard phenol/chloroform/isoamyl-alcohol extraction procedure. the dna was found to be sufficiently purified to generat ... | 2001 | 11393295 |
| outbreak of adenovirus genome type 7d2 infection in a pediatric chronic-care facility and tertiary-care hospital. | an outbreak of adenovirus infection that involved residents of a pediatric chronic-care facility, staff of a tertiary-care hospital, and a nosocomial hospital case was studied. in the pediatric facility, 31 (33%) of 93 residents had adenovirus infection, and 8 died. risk factors for illness were an age of < 7 years (p = .004), presence of a tracheostomy (p = .015), and residence on a particular floor (p < .001). in the tertiary-care hospital, 36 health care workers had adenovirus infection; 26 ( ... | 2001 | 11229836 |
| genome analysis of adenovirus type 7 and adenovirus type 11. | to study the epidemiology of adenovirus type 7 (ad 7) conjunctivitis and adenovirus type 11 (ad 11) conjunctivitis in the japanese population by determining the genome type and sub-genome type. | 2001 | 11163042 |
| a recent outbreak of adenovirus type 7 infection in a chronic inpatient facility for the severely handicapped. | 2000 | 11001256 | |
| adenovirus type 7 penton purification of soluble pentamers from escherichia coli and development of an integrin-dependent gene delivery system. | adenoviral gene therapy vectors suffer from the disadvantages of toxicity and immunogenicity associated with the expression of adenoviral genes from the vector backbone. we report here an alternative strategy for gene delivery that utilizes a single component of the adenoviral type 7 capsid, the penton base (ad7pb). the ad7pb gene was sequenced and its amino-acid composition was deduced from its nucleotide sequence. the penton was expressed in escherichia coli as a soluble c-terminal fusion with ... | 2000 | 10998069 |
| irreversible long-term pulmonary functional impairments after adenovirus type-7 pneumonia: assessment with xenon-133 ventilation and tc-99m maa perfusion studies. | a 3-year-old child presented with severe type-7 adenoviral pneumonia, after the resolution of diffuse pulmonary infiltrates of the pneumonia. xenon-133 ventilation and tc-99-m macroaggregated albumin (maa) perfusion studies revealed a localized airflow obstruction and matched perfusion defect, and marked air trapping in the remaining lungs, and these abnormalities were not detected and not suspected even with ct. thereafter, in a relatively short period, the child developed persistent bronchiect ... | 2000 | 10997429 |
| advances in the management of hemophagocytic lymphohistiocytosis. | hemophagocytic lymphohistiocytosis (hlh) is a prototype of the hemophagocytic syndrome and occurs most often in children. progress in cytokine research has now made it possible to show that hlh occurs as a consequence of uncontrolled, dysregulated cellular immune reactivity caused by a number of different underlying diseases. three major risk groups of hlh can be identified: (1) familial hlh (fhl), (2) epstein-barr virus-associated hlh (ebv-hlh), and (3) life-threatening infection-associated or ... | 2000 | 10979202 |
| genome analysis of adenovirus type 7 and adenovirus type 11 | purpose: to study the epidemiology of adenovirus type 7 (ad 7) conjunctivitis and adenovirus type 11 (ad 11) conjunctivitis by determining genome types and subgenomic types.materials and methods: for ad 7 i used twelve strains from patients with acute viral conjunctivitis and one strain from a patient with pneumonia. for ad 11 i used seventeen strains from patients with cystitis. for ad 7 genome typing, i used eleven dna restriction endonucleases (res) recognizing 6- or 7-base pair sequences and ... | 2000 | 10913656 |
| adenovirus type 7 outbreaks in japan in 1998. | 2000 | 10777856 | |
| [three cases with acute encephalopathy related with adenovirus type 7 infection]. | we studied the clinical and ct findings of 3 children with acute encephalopathy associated with adenovirus type 7 (ad-7) infection. seizures in all the patients developed from 8 to 10 days after the onset of pyrexia. the values of serum ast, ldh and crp elevated and those of wbc and serum protein decreased at the onset of encephalopathy. none of the patients had csf leukocytosis. ct showed mild brain atrophy in all patients. a steroid pulse therapy was effective in one patient. the pathogenesis ... | 2000 | 10655755 |
| [relationship between epidemiological data of adenovirus type 7 in kawasaki city and restriction enzyme assay pattern of the virus]. | since april 1995 increased number of type 7 were isolated in japan and also in kawasaki city. from may 1996 to march 1999, adenovirus type 7 (ad7) were isolated from 49 patients with high body temperature, and longer febrile period were observed in infants and younger children. lower respiratory tract infection occurred and a young child developed fatal pneumonia. ad7 were isolated not only in summer but in winter. they were prevalent all season. we analyzed 27 strains of ad7 genetically using r ... | 1999 | 10655683 |
| [genome analysis of adenovirus type 7 and adenovirus type 11]. | to study the epidemiology of adenovirus type 7 (ad 7) conjunctivitis and adenovirus type 11 (ad 11) conjunctivitis by determining genome types and subgenome types. | 1999 | 10589237 |
| molecular and serological characterization of adenovirus genome type 7h isolated in japan. | in 1996, three adenovirus type 7 (ad7) strains were isolated from children with fever and upper respiratory diseases in japan. restriction endonucleases (res) analysis and pcr amplification of the e3 7.7 kda orf revealed that these strains were genotype ad7h and closely related to an argentine ad7h strain, which has been reported to be highly virulent and so far predominant only in south america. these strains showed weak cross-neutralizing activity and specific haemagglutination-inhibition acti ... | 1999 | 10355793 |
| trend of adenovirus type 7 infection, an emerging disease in japan. a report of the national epidemiological surveillance of infectious agents in japan. | the program of the national epidemiological surveillance of infectious diseases under the auspices of the ministry of health and welfare started in 1981 apprehended in 1995 emergence of adenovirus type 7 in japan. we analyzed the reported data of type 7 comparing with those of type 3, both belonging to the same subgenus b, and the following results were obtained: after 1981, the main serotypes in the reports of adenovirus isolation/detection were types 3, 2, and 1 in this order. the reports of i ... | 1998 | 10211431 |
| [analysis of adenovirus type 7 hexon hypervariable region]. | the isolation of adenovirus type 7 (ad7) has been rare in japan in the past. however since april, 1995, many isolates of ad 7 have been reported. in order to find the cause of ad 7 re-emergence in japan, we investigated the genome sequences of ad 7 by analyzing the hexon hypervariable regions (hvrs). hvrs of genomes isolated before and after this prevalence showed little change and were closely related with each other. it was concluded that adenovirus hexon which contains hvrs is conserved in th ... | 1998 | 9785853 |
| outbreak of severe infection due to adenovirus type 7 in a paediatric ward in japan. | between november 1996 and january 1997, 14 patients were diagnosed as having infection caused by adenovirus type 7 in a paediatric ward of asahikawa kosei hospital. the age range of the patients was from two months to five years. their diseases and abnormal laboratory findings were pneumonia in all 14, leukocytopenia in 10, myositis in nine, gastroenteritis in eight, encephalitis in five, liver dysfunction in three, pleuritis in two, inappropriate secretion of antidiuretic hormone syndrome in tw ... | 1998 | 9699140 |
| [severe type 7 adenovirus pneumoniae in an immunocompetent adult]. | we report a case of severe adenovirus type 7 pleuropneumonia in an immunocompetent adult. the treatment required a mechanical ventilation with tracheostomy. the sequelae was a restrictive respiratory insufficiency. adenovirus is a common cause of pneumonia in children, in military recruits or in immunocompromised adults. however, it is an infrequent cause of such a severe complication in a healthy adult. | 1997 | 9686095 |
| genomic characterization of adenovirus serotype 7 isolated in brazil from acute respiratory disease patients during the period from 1980 to 1991. | forty isolates of adenovirus type 7 were analized by restriction enzyme digestion with bamhi, smai, ecori and hindiii. these isolates were obtained from acute respiratory disease patients during the years 1980 to 1991. only two genomic types were found: ad7b and ad7e, with ad7b (87.5%) being more frequent than ad7e (12.5%). the genomic type ad7e appeared in the years 1980, 1981 and 1983. ad7b appeared in 1982 and it was the only genomic type found from 1984 to 1991. both genomic types were respo ... | 1997 | 9640779 |
| molecular epidemiology of adenovirus type 7 in israel: identification of two new genome types, ad7k and ad7d2. | the molecular epidemiology of adenovirus type 7 in israel was investigated. fifty-seven adenovirus isolates identified as serotypes 7 or 7a which were recovered from patients in israel between 1968 and 1995 were analyzed by restriction enzymes digestion using bamhi for primary discrimination and identification of genome types and by six additional enzymes: bsteii, hpai, bgli, bglii, bcli, and xbai for confirmation and determination of genomic subtypes. four digestion patterns were identified wit ... | 1998 | 9557295 |
| [serosurvey for adenovirus type 3 and adenovirus type 7 infection in resident in gifu prefecture, 1996]. | 1997 | 9483890 | |
| construction of an adenovirus type 7a e1a- vector. | a strategy for constructing replication-defective adenovirus vectors from non-subgroup c viruses has been successfully demonstrated with adenovirus type 7 strain a (ad7a) as the prototype. an e1a-deleted ad7a reporter virus expressing the chloramphenicol acetyltransferase (cat) gene from the cytomegalovirus promoter enhancer was constructed with dna fragments isolated from ad7a, an ad7a recombination reporter plasmid, and the 293 cell line. the ad7a-cat virus particle transduces a549 cells as ef ... | 1997 | 9343264 |
| [analysis of genome types of adenovirus type 7 isolated in fukuoka prefecture in 1996]. | adenovirus type 7 (ad7) was rarely isolated in japan till 1994, but during april 1995 to august 1996, isolations of ad7 were reported 230 cases. we isolated ad7 in january and july 1996 in fukuoka prefecture. we analyzed its genome type by using 14 restriction endonuclease and studied seroepidemiology of ad7 infection in fukuoka prefecture. isolated ad7 strains were identical by 14 restriction endonuclease. between new ad7 isolates and prototype (gomen; ad7p), 4 restriction endonuclease patterns ... | 1997 | 9339625 |
| hydropathic characteristics of adenovirus hexons. | the complete nucleotide sequence and the predicted amino acid sequence of the adenovirus type 7 hexon gene were determined. the hydropathy of the hexon proteins from human adenovirus types 2, 3, 4, 5, 7, 12, 16, 40, 41, and 48, bovine adenovirus type 3, murine adenovirus type 1, and avian adenovirus types 1 and 10 was analysed. the presence of purines and pyrimidines in the second position of the codons was correlated to hydrophilicity and hydrophobicity, respectively. comparison of the hydrophi ... | 1997 | 9267445 |
| close phylogenetic relationship between egg drop syndrome virus, bovine adenovirus serotype 7, and ovine adenovirus strain 287. | a cloned egg drop syndrome (eds) virus genomic dna fragment containing the protease gene has been identified and the complete nucleotide sequence of the protease and partial nucleotide sequence of the hexon genes has been determined. phylogenetic analysis of the protease gene has revealed eds virus to be genetically more closely related to bovine adenovirus type 7 (bav-7) and ovine adenovirus isolate 287 (oav287) than either of these two viruses are to other members of the genus mastadenovirus o ... | 1997 | 9123875 |
| nucleotide and amino acid sequence analysis of the porcine adenovirus 23k protein. | the genomic location of the viral encoded protease (23k) of porcine adenovirus serotype 3 (pav3) was determined and the appropriate fragment cloned and sequenced. an open reading frame (orf) coding for a polypeptide of 203 amino acids and a calculated molecular weight of 23.3 kda was found. the orf was situated in a position similar to that of the human adenovirus 23k, that is, between a putative stop codon for the hexon gene and the polyadenylation signal, aataaa, for the late region 3. amino a ... | 1996 | 8912929 |
| hexon sequence of adenovirus type 7 and comparison with other serotypes of subgenus b. | the hexon gene of human adenovirus (av) type 7 (subgenus b) was sequenced. the determined nucleotide and the predicted amino acid sequences were compared to the corresponding sequences of av3 and av16. the hexons of av7 and av3 revealed an overall homology of 94.3% at the protein level, whereas the av7 and av16 hexons only showed an overall homology of 85.7%. utilizing the three-dimensional model of the av2 hexon, the structure of the av7 hexon was predicted. the major differences between the th ... | 1995 | 8834754 |
| isolation of adenovirus type 7 from the urine of children with acute hemorrhagic cystitis. | 1996 | 8823863 | |
| [a 12-year-old girl with acute respiratory disease with pneumonia caused by adenovirus type 7]. | we have encountered a 12-year-old girl with acute respiratory disease including pneumonia caused by adenovirus type 7. while being followed-up for bronchial asthma, she developed this disease with dyspnea accompanied by high fever, pharyngalgia and a dry cough subsequent to a slight fever. adenovirus type 7 was separated and identified from the pharyngeal smear. additionally, perfusion scintigraphy of the lungs presented evidence of interstitial pneumonia. with these findings and the clinical co ... | 1996 | 8699100 |
| comparative analysis of the structure and function of adenovirus virus-associated rnas. | the protein kinase dai is an important component of the interferon-induced cellular defense mechanism. in cells infected by adenovirus type 2 (ad2), activation of the kinase is prevented by the synthesis of a small, highly ordered virus-associated (va) rna, va rnai. the inhibitory function of this rna depends on its structure, which has been partially elucidated by a combination of mutagenesis and rnase sensitivity analysis. to gain further insight into the structure and function of this regulat ... | 1993 | 8411363 |
| effect of heparin on hemagglutination by pseudorabies virus. | heparin inhibited hemagglutination (ha) by pseudorabies virus (prv), but not ha by akabane virus, bovine adenovirus type 7, fukuoka virus, getah virus, japanese encephalitis virus, and parainfluenza virus type 3 belonging to the families bunyaviridae, adenoviridae, rhabdoviridae, togaviridae, flavivi-idae, and paramyxoviridae, respectively. the minimal inhibitory concentration of heparin required to inhibit 8 ha u of prv ranged from 0.005 to 0.01 u/ml. mouse erythrocytes failed to combine with t ... | 1993 | 8381261 |
| tumorigenicity of adenovirus-transformed rodent cells is influenced by at least two regions of adenovirus type 12 early region 1a. | chimeric adenovirus type 5 (ad5)/ad12 early region 1a (e1a) genes were used to transform primary baby rat kidney cells in cooperation with ad12 e1b, and the resulting cell lines were assayed for tumorigenicity in syngeneic rats. it was found that lines were nontumorigenic when transformed by hybrid e1a genes consisting of the amino-terminal 80 amino acids from ad12 including conserved region 1 (cr1), with the remaining portion from ad5. in contrast, cell lines transformed by hybrids containing a ... | 1994 | 8289391 |
| constructing chimeric type 12/type 5 adenovirus e1a genes and using them to identify an oncogenic determinant of adenovirus type 12. | the e1a gene of highly oncogenic type 12 adenovirus (ad12) possesses a segment unique to this serotype and comprising 60 base pairs contiguous with and separating conserved regions 2 and 3 in the gene. a similar but slightly longer segment is also present in the e1a gene of highly oncogenic simian adenovirus type 7 (d. kimelman, j. s. miller, d. porter, and b. e. roberts, j. virol. 53:399-409, 1985). this segment is missing entirely from the e1a gene of type 5 adenovirus, which is nononcogenic. ... | 1994 | 8289390 |
| sequence and functional analysis of the human adenovirus type 7 e3-gp19k protein from 17 clinical isolates. | the adenovirus (ad) early region 3 (e3) glycoprotein of 19k (gp19k) binds major histocompatibility (mhc) class i antigens in the endoplasmic reticulum (er), and the gp19k-class i complex is retained in the er through an er retention signal at the c-terminus of gp19k. this retention of class i antigens blocks cytolysis of gp19k-expressing cells by cytotoxic t lymphocytes (ctl). animal models infected with ad mutants lacking gp19k support a role for gp19k in counteracting a ctl response. gp19k bin ... | 1993 | 8249282 |
| isolation and characterization of adenovirus-associated va rnas of human adenovirus type 7. | two genes for virus-associated va rnas in the human adenovirus type 7 (ad7) genome are compared to ad2, ad4, ad5, simian va rnas, and pol iii transcripts of epstein-barr virus. the newly identified va rna-encoding genes of ad7 contain two relatively conserved intragenic promoter (elements a and b), the double-stranded rna-dependent protein kinase (pk) active site-binding domain and transcriptional terminators. the conserved features extend to the va rna genes of simian and avian origin. | 1994 | 8194770 |
| [the genomic variability of adenovirus serotype 7]. | genetic heterogeneity and evolutionary relationships among selected strains of adenovirus type 7 (ad7) isolated in the former ussr were examined using the restriction endonuclease cfr131 with a 4-base recognition cleavage site. the population of adenovirus type 7 showed less expressed genome polymorphism and significant structural distinctions as compared with that of adenovirus type 3. the ad7 evolution in the ussr (1976-1988) independent on that demonstrated in other countries is discussed. | 1994 | 8160439 |
| construction and characterization of adenovirus co-expressing hepatitis b virus surface antigen and interleukin-6. | coexpression of biologically active interleukin 6 (il-6), an immunoregulator, and hepatitis b virus surface antigen (hbsag), an immunogen, was obtained using an adenovirus type 7 (ad7) vector. two recombinant adenoviruses (re-ad) containing both the hbsag and il6 genes were constructed: one virus was capable of expressing il6 with its signal peptide (spil6) (ad7::spil6::hbsag), and the second virus lacked this sequence (ad7::il6::hbsag). a third recombinant contained only hbsag (ad7::hbsag). all ... | 1994 | 8125296 |
| [detection of a new genomic variation of adenovirus 7 associated to severe infections of the lower respiratory tract]. | we report a new genomic variation of adenovirus 7, associated to severe infections of the lower respiratory tract isolated during september 1990, from children under 3 years of age and living in buenos aires city. the restriction analysis with the bamhi, bgli, bglii and smai restriction endonucleases demonstrated that the new variation is highly related to the recently described adenovirus 7h. | 1993 | 8114625 |
| restriction endonuclease analysis of bovine herpesvirus type 1 isolates from calves with fatal encephalitis: comparison with vaccine virus. | meningo-encephalitis in feedlot cattle sporadically occurred in the tokachi area in northern japan. the calves had been vaccinated intranasally with a mixed live-vaccine (infectious bovine rhinotracheitis virus, bovine viral diarrhea-mucosal disease virus, and parainfluenza 3 virus) for which intramuscular inoculation was indicated. two additional live vaccines, bovine adenovirus type 7 and bovine respiratory syncytical virus, had been inoculated simultaneously. eleven isolates of bovine herpesv ... | 1995 | 7548427 |
| in vitro cell transformation screening of 4 toluene diamine isomers. | 2,4-, 2,5-, 2,6- and 3,4-toluene diamine (tda) were tested for their ability to enhance the transformation of primary hamster embryo cells (hec) by simian adenovirus 7 (sa7) when administered either prior to or after virus inoculation and for their ability to transform secondary hec. 2,4-tda was inactive when given prior to sa7, but active if given after. 2,5-tda was active in both protocols. 2,6-tda was marginally active if administered before virus and was the most active of the isomers when a ... | 1980 | 7442705 |
| the distribution of guanine-cytosine pairs in adenovirus dnas. | the distribution of guanine-cytosine (gc) pairs in the dna of the highly oncogenic simian adenovirus type 7 (sa7) and the non-oncogenic human adenovirus type 6 (ad6) has been studied by thermal denaturation and csc1 density-gradient centrifugation. the differential of the dna thermal denaturation curves shows the presence of pronounced peaks which indicates uneven distribution of gc pairs along the dna chains and the presence of regions with gc content from 30 to 74% in sa7 dna and from 40 to 68 ... | 1981 | 7288411 |
| a nonessential glycoprotein is coded by early region e3 of adenovirus type 7. | 1981 | 7257191 | |
| [peptide mapping of the hexon and internal protein of type 6 human and type 7 simian adenoviruses]. | hexons (polypeptide 11) and core proteins (polypeptide v) of human adenovirus type 6 and simian adenovirus type 7 were isolated using electrophoresis in polyacrylamide gel. tryptic peptide maps showed the similarity but not identify in the structure of proteins studied. this method seems to be the most suitable for comparison of relative viral proteins. | 1981 | 7248505 |
| a sixth species of ovine adenovirus isolated from lambs in new zealand. | two adenoviruses (wv419/75 and wv757/75), isolated from lambs in new zealand were compared using neutralisation tests with the five recognised ovine adenovirus species, nine bovine and four porcine adenoviruses. wv419/75 did not cross-react with any of the viruses tested and represents a new ovine adenovirus species (oav-6). wv757/75 cross-reacted with bovine adenovirus type 7 (bav-7) with a homologous to heterologous titre ratio of 16 in one direction only, and also showed a substantial one-way ... | 1982 | 7165512 |
| cytologic detection of virus-specific dna by in situ hybridization in syrian hamster embryo cells transformed by viral or combined chemical and viral treatment. | a series of simian adenovirus 7 (sa7)-transformed syrian hamster cell lines that had t antigen and produced tumors in neonatal hamsters were examined by radioautography in conjunction with in situ molecular hybridization to determine the extent to which the viral genome is integrated on specific chromosomes and the consequences of such integration on sister chromatid exchange (sce) frequency. no consistent cytological or chromosomal localization of viral dna in situ hybridization with viral comp ... | 1982 | 7151038 |
| restricted replication of mouse adenovirus strain fl in mouse balb/c cells transformed by simian adenovirus 7. | 1982 | 7064348 | |
| gene organization of the transforming region of weakly oncogenic adenovirus type 7: the e1a region. | the structures of adenovirus type 7 (ad7) cytoplasmic rnas transcribed from the leftmost 4.5% of the viral genome during lytic infection of kb cells have been determined. the e1a region was found to specify three differently spliced mrnas (i, ii and iii) which have common 5' and 3' termini. mrnas i and ii are transcribed between identical initiation and termination codons and code for polypeptides of 28 kd and 24 kd, whose only difference is an internal sequence of 32 amino acids present in the ... | 1980 | 6985480 |
| the influence of iododeoxyuridine pretreatment of various cell cultures on adenovirus multiplication. | treatment of cell cultures with iododeoxyuridine (iudr) before virus inoculation may enhance the subsequent virus multiplication. this effect was studied in seven kinds of cell cultures with seven human adenoviruses from six subgenera. iudr (50 micrograms/ml) was added 24 h after the seeding of cells, left for 2 days, and removed before virus inoculation. iudr had no effect on cell proliferation. viral cytopathic effect was enhanced in many instances by iudr pretreatment. however, virus multipli ... | 1983 | 6343819 |
| sequence of the dna-binding protein gene of a human subgroup b adenovirus (type 7). comparisons with subgroup c (type 5) and subgroup a (type 12). | the adenovirus type 7 (ad7) single-stranded dna-binding protein (dbp) structural gene has been sequenced and located between 66.7 and 62.3 map units. this region codes for a protein that contains 517 amino acid residues with a calculated molecular mass of 58,240 daltons. we compared the ad7 amino acid sequence with those reported for the ad5 (kruijer, w., van schaik, f.m.a., and sussenbach, j.s. (1981) nucleic acids res. 9, 4439-4457) and ad12 (kruijer, w., van schaik, f.m.a., speijer, j.g., and ... | 1984 | 6325415 |
| structural comparisons of wild-type and nuclear transport-defective simian virus 40 large tumor antigens. | para(nt) is a defective sv40-adenovirus 7 hybrid virus which contains the entire early region of the sv40 genome and codes for the synthesis of sv40 large tumor antigen (t-ag). a transport-defective variant of this hybrid, para(ct), encodes t-ag that is not transported to the nucleus, but accumulates in the cytoplasm. the structures of t-ags extracted from wild-type (wt) sv40-, para(nt)-, and para(ct)-infected cells were compared by peptide mapping. all three types of t-ag underwent considerable ... | 1984 | 6324467 |
| differential extraction of tumor-specific transplantation antigen and embryonic antigen from simian virus 40- and adenovirus 7-induced sarcoma cells of hamsters with 1-butanol and 3 m potassium chloride. | simian virus 40 (sv40)-induced sarcomas and adenovirus 7-induced sarcomas (adv-7) exhibit both specific tumor-specific transplantation antigens (tsta) and cross-protective embryonic antigens at the cell surface in the lak:lvg(syr) strain of syrian golden hamsters. specific sv40 tsta could be released from the surfaces of living hamster sarcoma cells in a 2.5% crude 1-butanol extract (cbe) and served as immunogen to protect syngeneic recipients against subsequent homologous but not heterologous t ... | 1984 | 6323810 |
| differential phosphorylation of cytoplasmic and nuclear variants of simian virus 40 large t antigen encoded by simian virus 40-adenovirus 7 hybrid viruses. | the phosphorylation patterns of cytoplasmic and nuclear forms of simian virus 40 large t antigen encoded by simian virus 40-adenovirus 7 hybrid viruses were analyzed by two-dimensional peptide mapping. the para(ct) mutant which encodes a large t antigen defective for nuclear transport was used as source for cytoplasmic large t antigen. the data suggest that the large t antigen is phosphorylated in a sequential manner at a subset of sites in the cytoplasm and at additional sites in the nucleus. | 1984 | 6323765 |
| variation of virus replication in primary bovine kidney cell cultures derived from 68 three-day-old calves. | primary kidney cell cultures were prepared from 68 three-day-old calves. complete monolayers of these cultures were infected separately with viral diarrhea, infectious bovine rhinotracheitis, parainfluenza, and adenovirus 7 viruses. the yield of virus from all infected cultures was calculated by plaque titer assay after 2 to 4 days' incubation. the variation of virus yield was substantial between individual cultures. | 1983 | 6318615 |
| haematemesis as a presentation of adenovirus type 7 infection. | 1983 | 6316891 | |
| prevalence of bovine herpesvirus-1, parainfluenza-3, bovine rotavirus, bovine viral diarrhea, bovine adenovirus-7, bovine leukemia virus and bluetongue virus antibodies in cattle in mexico. | 1983 | 6316006 | |
| extracorporeal membrane oxygenation: its role in the survival of a child with adenoviral pneumonia and myocarditis. | we report the case of a 2-year-old child with severe adenovirus type 7 pneumonia and myocarditis who survived after seven days of ecmo. our patient demonstrates the possible applications of ecmo to pediatric lung diseases and reemphasizes the importance of lung biopsy in screening possible candidates. | 1983 | 6310796 |
| viral infections of the respiratory tract in hospitalized children. a study from oslo during a 90 months' period. | a diagnosis of 979 respiratory viral infections was made in hospitalized children. respiratory syncytial virus greatly out-numbered the other viruses: it caused 58% of the total virus infections and occurred in winter epidemics. influenza a and b virus occurred during late winter and spring, rhinovirus had a seasonal distribution towards spring and autumn, whereas adenovirus types 1, 2 and 5 had no distinct seasonal distribution. whereas respiratory syncytial virus were mainly associated with br ... | 1983 | 6305106 |
| adenovirus type 7 outbreak in a pediatric chronic-care facility--pennsylvania, 1982. | 1983 | 6302468 | |
| adenovirus type 7b in a children's hospital. | between august 15 and september 15, 1980, an outbreak of infections due to adenovirus type 7b occurred at children's hospital and health center, san diego, california. during that time, four of six patients infected with adenovirus type 7b died. all patients with hospital-acquired disease had underlying respiratory compromise. cultures, adenoviral serology tests, and histories were obtained from 383 (93%) of the 410 hospital employees. all 11 people from whom adenovirus type 7 was cultured were ... | 1983 | 6302176 |
| the nucleotide sequence of the genes encoded in early region 2b of human adenovirus type 7. | the nucleotide sequence of a cloned dna segment encoding the early region 2b from the group b human adenovirus ad7 has been determined. when compared to ad2, a group c adenovirus, these sequences were found to be approx. 80% homologous within the l-strand gene-coding regions. most changes are transitions or transversions, although several deletions/insertions also occur within the n-terminal domain of one of the coding regions. the substantial nucleotide homology results in a high degree of amin ... | 1983 | 6301944 |
| comparative sequence analysis of the inverted terminal repetition in the genomes of animal and avian adenoviruses. | the nucleotide sequences at the inverted terminal repetitions from two animal adenoviruses, infectious canine hepatitis virus and equine adenovirus, and from one avian adenovirus, celo, were analyzed. dnas from infectious canine hepatitis virus and equine adenovirus contain a homologous region which is 23 nucleotides long from the terminus. the first 17 nucleotides of this region are identical to the ones in human adenovirus type 2 dna. the striking homologous sequence of 14 nucleotides, conserv ... | 1983 | 6301151 |
| acute encephalopathy in twins due to adenovirus type 7 infection. | 1983 | 6293428 | |
| the nucleotide sequence of the gene encoding protein iva2 in human adenovirus type 7. | the nucleotide sequences of cloned dna segments encoding the iva2 gene from ad7 and a portion of ad12 (group b and group a human adenoviruses, respectively) have been determined. when compared to ad5, a group c adenovirus, these sequences have been found to be 80% homologous. most changes are transitions or transversions. this high degree of nucleotide homology results in a high degree of amino acid conservation in the predicted polypeptides encoded from these genes; most nucleotide changes occu ... | 1982 | 6292051 |
| hyperlucent lung: long-term complication of adenovirus type 7 pneumonia. | 1983 | 6291737 | |
| gene organization of the transforming region of adenovirus type 7 dna. | the sequence of the leftmost 11% of the weakly oncogenic human adenovirus type 7 (ad7) dna has been determined. this part of the ad7 viral genome encompasses early region e1 which has been shown to be involved in the process of cell transformation in vitro (dijkema et al., 1979). from the nucleotide sequence and determined coordinates of the e1 mrnas, we are able to predict the primary structure of the polypeptides encoded by the transforming region of ad7. the organization of the e1 region of a ... | 1982 | 6290319 |
| physical mapping of human adenovirus type 7 dna using a simple and sensitive method of terminal labeling. | the tyrosine-containing peptide covalently attached to each 5'-terminus of adenovirus type 7 (ad 7; greider) dna was labeled with 125i. the 5'-labeled dna was subjected to digestion with several restriction endonucleases and the size of the labeled terminal fragments was determined. partial hydrolysis by these endonucleases generated a series of labeled fragments which were fused to the terminal fragments and could, therefore, be detected by autoradiography. from the sizes of the partial product ... | 1982 | 6290317 |
| [simian adenovirus genome. ii. identification of specific fragments of viral dna possessing transforming activity]. | the antigenic variant of simian adenovirus 7 (sa7) dna was cleaved by restriction endonucleases ecori, xbai, bamhi, sali. the resulted digests of viral dna were tested for transforming activity using the "calcium" technique. it was shown that bamhi. xbai and sali digests transformed primary baby rat kidney cells as well as native viral dna. the transforming activity of separated bamhi and sali fragments was tested also. the viral dna fragments with transforming activity (bamhi-b and sali-b) were ... | 1982 | 6280036 |
| integration of foreign genome fragments into cells transformed or cotransformed with fragmented adenoviral dna. | the integration of dna of highly oncogenic simian adenovirus type 7 (sa7) and non-oncogenic human adenovirus type 6 (ad6) into the genome of newborn rat kidney cells transformed by fragmented dna preparations was studied using reassociation kinetics and spot hybridization. transforming dna was fragmented with the specific endonuclease sali (sa7) and bglii (ad6). in contrast to the cell transformation by intact viral dna, transformation by fragmented dna resulted in integration into the cellular ... | 1981 | 6277738 |
| lobar pneumonia associated with adenovirus type 7. | 1981 | 6277442 | |
| molecular epidemiology of adenoviruses: alternating appearance of two different genome types of adenovirus 7 during epidemic outbreaks in europe from 1958 to 1980. | four genome types of adenovirus serotype 7 (ad7, ad7a, ad7b, and ad7c) were identified by use of dna restriction enzymes bamhi, ecori, and smai. we obtained information on the distribution of the four ad7 genome types by typing 68 ad7 isolates obtained in the netherlands from 1958 to 1979 and 36 ad7 isolates obtained in sweden from 1964 to 1980. the ad7 prototype was never detected, and only seven isolates were genome-typed ad7a. ad7b and ad7c accounted for 94% of the genome-typed isolates obtai ... | 1981 | 6273316 |
| the gene for polypeptide ix of human adenovirus type 7. | this paper describes the nucleotide sequence of subgroup b human adenovirus type 7 (ad7) between positions 3351-4010, and of cloned cdna derived from mrnas encoded by this segment. one of these (mrna vii) is shown to be unspliced, and has its 5'- and 3'-ends encoded by positions 3460 (determined by the nuclease s1 technique) and 3939, respectively. the mrna sequence contains a single open reading frame for protein biosynthesis between the first available initiation triplet aug at position 3481 t ... | 1981 | 6266923 |
| chronic lung damage caused by adenovirus type 7: a ten-year follow-up study. | twenty-seven children aged 0.6 to 7.0 (mean 2.1) years were admitted to the hospital in 1967 and 1968 with type 7 adenoviral pneumonia. all ran a prolonged course. type 7 adenovirus was isolated from 14 children, and in the other 13, the rise in the titer of complement-fixing antibodies to adenovirus was fourfold or greater. the outcome of the disease in these 27 children was reassessed in 1979, 9.6 to 12.1 (mean 10.7) years after the adenovirus type 7 pneumonia. twenty-two were examined clinica ... | 1981 | 6265156 |
| prevention of primary simian adenovirus type 7 (sa7) tumors in hamsters by adoptive transfer of lymphoid cells: role of different cell types. | 1981 | 6261538 | |
| subgenomic viral dna species synthesized in simian cells by human and simian adenoviruses. | dna synthesized after infection of simian tissue culture cells (bsc-1 or cv-1) with human adenovirus type 2 or 5 or with simian adenovirus 7 was characterized. it was demonstrated that as much as 40% of the virus-specific dna in nuclei of infected monkey cells consists of subgenomic pieces. no subgenomic viral dna species were detected in the nuclei of human (hela) cells infected with these adenovirus types. restriction analysis showed that these short viral dna molecules contain normal amounts ... | 1981 | 6261009 |
| virus infection of endothelial cells. | endothelial injury is important in the pathogenesis of thrombosis, atherosclerosis, disseminated intravascular coagulation, and vasculitis. the ability of several common human viruses to infect cultures of endothelial cells obtained from human umbilical veins or bovine thoracic aorta was demonstrated. indicators of infection included cytopathology, viral growth curves, and antigen detection by immunofluorescence. herpes simplex virus type 1, adenovirus type 7, measles virus, and parainfluenza vi ... | 1981 | 6260874 |
| properties of simian adenovirus 7 after one single passage in simian marmoset lymphoblastoid cells transformed by epstein barr virus. | simian adenovirus 7 gave an abortive infection in simian marmoset lymphoblastoid cells, b 95-8 and m 81 (transformed by epstein barr virus) whereas non transformed simian lymphocytes could not replicate this virus. electron dense incomplete particles with a lower density than standard virus in cscl gradients were isolated. virus yields were low and the percentage of cells containing viral antigen as measured by immunofluorescence was 0.01% for b 95-8 cells and still less for the m 81 cells. afte ... | 1980 | 6256015 |
| [cloning of fragments of simian adenovirus 7 dna in escherichia coli bacteria using plasmid vector pbr322]. | 1980 | 6254743 | |
| epidemic outbreaks of adenovirus 7 with special reference to the pathogenicity of adenovirus genome type 7b. | adenovirus type 7 (ad 7) is the serotype among the 36 recognized adenovirus types which most frequently has been associated with severe illness. three different epidemic patterns of ad 7 infection can be distinguished: 1) the first appears during the winter among infants with median age below two years, has characteristic symptoms of high fever and pneumonia and an outcome that may be fatal: 2) the second appears in the fall among children with median age seven years, has characteristic symptoms ... | 1980 | 6254358 |
| unique species of mrna from adenovirus type 7 early region 1 in cells transformed by adenovirus type 7 dna fragment. | adenovirus type 7 (ad7) early region 1 mrna species transcribed in rat cell lines transformed by the hindiii-i . j fragment (the left 7.8% of the viral genome) and in human kb cells infected with ad7 were mapped on the viral genome, using s1 nuclease gel and diazobenzyloxymethyl paper hybridization techniques. at the early stage of productive infection, two mrna's (950 and 840 nucleotides long) with the common 5' and 3' ends but different internal splicings were mapped from region 1a (map units ... | 1980 | 6253660 |
| biochemical characterization of nuclear and cytoplasmic forms of sv40 tumor antigens encoded by parental and transport-detective mutant sv40-adenovirus 7 hybrid viruses. | 1980 | 6252683 | |
| inhibition of nuclear migration of wild-type sv40 tumor antigen by a transport-defective mutant of sv40-adenovirus 7 hybrid virus. | 1980 | 6252682 | |
| [cloning simian adenovirus 7 dna fragments in escherichia coli bacteria using plasmid vector pbr322]. | 1980 | 6252003 | |
| the nucleotide sequence of the transforming bglii-h fragment of adenovirus type 7 dna. | the nucleotide sequence of the leftmost bglii-h fragment (0--4.5%) of weakly oncogenic human adenovirus serotype 7 (ad7) has been determined (1568 base pairs). this is the shortest ad7 dna fragment reported to transform primary rat cells into an immortal cell line (dijkema et al., 1979). the l-strand of bhlii-h was found to contain the complete information for a polypeptide of at most 28 051 daltons, followed by the putative promoter site of the next gene. comparison of the determined ad7 sequen ... | 1980 | 6247243 |
| a seroepidemiologic survey of three pronghorn (antilocapra americana) populations in southeastern idaho, 1975-1977. | sera from 104 adult and 42 fawn pronghorn antelope (antilocapra americana) from southeastern idaho were tested against selected livestock pathogens. the numbers positive/numbers tested (% positive) were as follows: bovine virus diarrhea - adults 2/102 (2), fawns 0/41 (0);; infectious bovine rhinotracheitis - adults 27/101 (27), fawns 9/42 (22); parainfluenza 3 - adults 79/104 (76), fawns 22/42 (52); bovine adenovirus 7 - adults 42/103 (41), fawns 20/48 (48); bovine adenovirus 3 - adults 11/32 (3 ... | 1980 | 6246285 |
| antiviral effects of bovine interferons on bovine respiratory tract viruses. | the antiviral effects of bovine interferons on the replication of bovine respiratory tract viruses were studied. bovine turbinate monolayer cultures were treated with bovine interferons and challenged with several bovine herpesvirus 1 strains, bovine viral diarrhea virus, parainfluenza type 3 virus, goat respiratory syncytial virus, bovine respiratory syncytial virus, bovine adenovirus type 7, or vesicular stomatitis virus. treatment with bovine interferons reduced viral yield for each of these ... | 1984 | 6201505 |
| [oligopeptide analysis of the hexons of human adenovirus types 1, 2 and 6 and simian adenovirus sa7]. | a comparative analysis of hexons of human adenovirus (hadv) types 1, 2, 6 and simian adenovirus type 7 (sa7) was carried out by peptide mapping. common and unique peptides were found in hexons from virions of human adenovirus types 2 and 6 and sa7. the similarity of hexons of hadv types 2 and 6 was shown to be more marked than hadv and sa7 hexons. similar data were obtained in the analysis of excessively synthesized (soluble) hexons of hadv types 1 and 6 and sa7. a significant homology between ... | 1981 | 6175108 |
| induction of delta 3(4) ketosteroid synthesis by interferon in mouse adrenal tumour cell cultures. | interferon, like cholera toxin, induces in mouse adrenal yi cells the production of delta 3(4) ketosteroids. in parallel, cyclic amp (camp) is activated. at high concentrations, mouse but not human interferon induces a cell rounding effect, similar to that obtained with cholera toxin. in yi cells transformed by simian adenovirus 7, production of camp is still increased by that of steroids is blocked. the role if interferon in these cellular events is discussed. | 1980 | 6161994 |
| factors predisposing to abnormal pulmonary function after adenovirus type 7 pneumonia. | adenoviruses are well known causes of respiratory illness in children. long term sequelae reported with types 3, 7, and 21 include bronchiolitis obliterans, bronchiectasis, and the hyperlucent lung or mcleod syndrome. twenty children admitted to hospital with adenovirus type 7 pneumonia between 1960 and 1978 were studied and compared with 20 controls admitted during the same period with adenovirus type 7 upper respiratory tract infections. sixty five per cent of the pneumonia group had developed ... | 1984 | 6093715 |
| restriction analysis and homology studies of the bovine adenovirus 7 genome. | we located the cleavage sites for restriction endonucleases ecori, hindiii, and bamhi on the genome of bovine adenovirus 7. cross-hybridization at reduced stringency revealed two regions of homology shared by the dna of human adenovirus 2 and bovine adenoviruses 7 and 3. these regions correspond to the hexon and the iva2 protein genes of the human adenovirus. another region of homology shared only by the human adenovirus and bovine adenovirus 7 corresponded to the penton or the polypeptide iiia ... | 1984 | 6088811 |
| construction and characterization of an sv40 mutant defective in nuclear transport of t antigen. | an sv40-adenovirus 7 hybrid virus, para(ct), has been described that is defective for the nuclear transport of sv40 large tumor antigen. an sv40(ct) mutant was constructed using sv40 early and late region dna fragments derived from para(ct) and wild-type sv40 respectively. the sv40(ct)-3 construct is defective for viral replication, but can be propagated in cos-1 cells. t antigen induced by sv40(ct)-3 is localized in the cytoplasm of infected cells. the ct mutation also inhibits the transport of ... | 1984 | 6086146 |