Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| effect of cortisone and x-irradiation on the course of trypanosoma lewisi infection in the rat. | 1961 | 13713517 | |
| effect of salicylates and related compounds on ablastic response in rats infected with trypanosoma lewisi. i. isomers of salicylic acid. | 1961 | 13688445 | |
| electrophoretic and ultracentrifugal studies of antibodies to trypanosoma lewisi. | 1959 | 13665055 | |
| the effect of some metabolic inhibitors on the oxygen uptake of trypanosoma lewisi and trypanosoma equiperdium. | 1958 | 13566863 | |
| the oxygen uptake of trypanosoma lewisi and trypanosoma equiperdum, with especial reference to oxygen consumption in the presence of amino-acids. | 1958 | 13566862 | |
| some considerations relative to the nature of immunity in trypanosoma lewisi infections. | 1958 | 13539705 | |
| the ingestion of particulate fat from the blood by trypanosoma lewisi and trypanosoma equiperdum. | 1957 | 13504862 | |
| growth of trypanosoma lewisi in the heterologous mouse host. | 1958 | 13501231 | |
| immunization against trypanosoma lewisi in rats by injections of metabolic products. | 1957 | 13401232 | |
| effects of hypoxia on rats infected by trypanosoma lewisi. | 1956 | 13319771 | |
| the effect of salicylate treatment on plasma proteins in rats infected with trypanosoma lewisi. | 1956 | 13305593 | |
| [observations of trypanosoma lewisi (kent) in rats of aquila]. | 2014 | 13288924 | |
| observations on trypanosoma lewisi and grahamella sp. in the blood of rats from the hamakua district, island of hawaii. | 1954 | 13202016 | |
| the oxidative metabolism of trypanosoma lewisi from salicylate treated infected white rats. | 1954 | 13202012 | |
| effect of sodium salicylate treatment on antibody titers in rats infected with trypanosoma lewisi. | 1953 | 13120947 | |
| incidence of trypanosoma lewisi and hepatozoon muris in the norway rat. | 1952 | 12981595 | |
| activity of d-carnitine and its derivatives on trypanosoma infections in rats and mice. | little progress has been made in the treatment of african trypanosomiasis over the past decades. l-carnitine has a major role in glycolysis-based energy supply of blood trypanosomes for it stimulates constant atp production. to investigate whether administration of the isomer d-carnitine could exert a competitive inhibition on the metabolic pathway of the l-form, possibly resulting in parasite replication inhibition, several formulations of this compound were tested on trypanosoma lewisi and t. ... | 2003 | 12847922 |
| some field and laboratory studies on rattus rattus subspecies and rattus norvegicus in two egyptian governorates of different ecological characters. | both damietta and qualyobia governorates were examined for the seasonal activities of rattus species and subspecies and their natural infection with trypanosoma lewisi. the common domestic rodents identified were rattus r. alexandrinus, r. r. frugivorus and rattus norvegicus. they were common all the year round except in winter for r. norvegicus in damietta. gravid females of the three rodent species, were identified in damietta in summer, in addition to autumn for r. norvegicus only. in qualyob ... | 2002 | 12512813 |
| comparative positions of kinetoplasts in trypanosoma musculi and trypanosoma lewisi during development in vitro. | the development of trypanosoma musculi and trypanosoma lewisi were studied in vitro in the presence of adherent splenic cells. both parasites developed only when attached by their flagellar tips to adherent splenic cells. during the proliferation of t. musculi, the kinetoplast migrated towards the nucleus, and once in the vicinity of the nucleus, the nuclear division was triggered. the kinetoplast of t. lewisi did not migrate towards the nucleus, but remained at its original location. the nucleu ... | 2002 | 12269904 |
| pcr identification of trypanosoma lewisi, a common parasite of laboratory rats. | trypanosoma (herpetosoma) lewisi is a trypanosome of the sub-genus herpetosoma (stercoraria section), parasite of rats (rattus rattus and rattus norvegicus) transmitted by fleas. t. lewisi has a stringent species specificity and cannot grow in other rodents such as mice. rats are infected principally by oral route, through contamination by flea faeces or ingestion of fleas. trypanosoma lewisi infections in rat colonies can interfere with research protocols and fleas of wild rats are often the so ... | 2002 | 12234387 |
| prevalence of trypanosoma lewisi in rattus norvegicus from belo horizonte, state of minas gerais, brazil. | from april 1984 to march 1985, a trypanosoma lewisi prevalence of 21.7% was found in 429 rattus norvegicus trapped in belo horizonte, state of minas gerais, brazil. the infection rates were higher in male and young rats and could be attributed to ecological and behavioral factors. t. lewisi was observed in rats measuring between 60 and 250 mm. data about monthly t. lewisi infections throughout the year are presented for the first time in brazil, with the highest prevalences observed in the warm- ... | 2002 | 12048574 |
| infection of white rat peritoneal macrophages with toxoplasma gondii, (coccidia: sarcocystidae) after trypanosoma lewisi (kinetoplastida: trypanosomatidae) infection. | peritoneal macrophages from wistar rats, inoculated and non-inoculated with 10(6) t. lewisi trypomastigotes, were cultured and infected with 10(6) t. gondii tachyzoites. multiplication rates of this parasite were studied after 1, 24 and 48 h of infection but there were not significant differences between the number of parasites found inside of macrophages coming, either from t. lewisi infected or non infected rats. on the other hand, in vivo studies of toxoplasma multiplication inside peritoneal ... | 1999 | 10883328 |
| schistosoma japonicum in the black rat, rattus rattus mindanensis, from leyte, philippines in relation to oncomelania snail colonies with reference to other endoparasites. | this study examined the prevalence of schistosoma japonicum infections in field rats, rattus rattus mindanensis, according to different trapping locations. between october 1995 and january 1996, traps were set in the municipality of palo, leyte, philippines to determine the correlation of rats infected with schistosomiasis to the proximity of the intermediate snail host, oncomelania hupensis quadrasi, colonies. of the 22 rats that were caught within a snail colony, 21 (95.5%) were positive for s ... | 1999 | 10774707 |
| effect of trypanosoma lewisi (kinetoplastida: trypanosomatidae) on the infection of white rats with toxoplasma gondii (eucoccidia: sarcocystidae) oocysts. | white rats were inoculated with 10(6) trypomastigotes of trypanosoma lewisi, simultaneously or two days before and after inoculation with 10(5) oocysts of t. gondii. a greater number of cysts was found in the brain of the animals having concomitant inoculations, as compared with rats inoculated with either one of the two parasites. an apparent immunosuppressive effect is likely. since both organisms can be found in rats, it is possible that infections with t. lewisi, could make this rodent anoth ... | 1998 | 10751936 |
| increasing of toxoplasma gondii (coccidia, sarcocystidae) infections by trypanosoma lewisi (kinetoplastida, trypanosomatidae) in white rats. | to demonstrate that t. lewisi infection increases t. gondii multiplication in white rats, groups of five wistar or sprague dawley rats were inoculated with 10(6) t. lewisi trypomastigotes and four or seven days later infected with toxoplasma tachyzoites. host survival time was monitored, and the presence of t. gondii was confirmed in all dead rats by studying peritoneal exudate smears and lung tissue sections stained with haematoxylin-eosin. the presence of toxoplasma cysts or antibodies was che ... | 1997 | 9458990 |
| homologues of the 24-kda flagellar ca(2+)-binding protein gene of trypanosoma cruzi are present in other members of the trypanosomatidae family. | a full-length cdna encoding the 24-kda flagellar ca(2+)-binding protein (fcabp) of the dm28c clone of trypanosoma cruzi was cloned and characterized. comparison of the deduced amino acid sequence with those of the fcabps of other t. cruzi strains revealed greater than 97% sequence conservation. fcabp-like genes are found in trypanosoma conorhini, trypanosoma freitasi, trypanosoma lewisi, herpetomonas megaseliae, leptomonas seymouri, and phytomonas serpens, but not in crithidia deanei, leishmania ... | 1997 | 9225770 |
| [prevalence of protozoa infections in synanthropic rodents in valdivia city, chile]. | in order to determine the prevalence of infection by blood and intestinal protozoa in 57 synanthropic rodents from valdivia city, a study was carried out in the period march-september 1986. the group of rodents studied was constituted by 31 mus musculus, 19 rattus rattus and 7 oryzomys longicaudattus, being 42 males and 15 females. diagnostic forms of protozoa were found in 70.2% of the investigated animals. the presence of five species of enteroprotozoa and one species of hemoflagelate was dete ... | 1995 | 8762669 |
| oral transmission of trypanosomes of the subgenus herpetosoma from small mammals. | the rodents microtus agrestis, clethrionomys glareolus, apodemus sylvaticus and white bk rats were given either a single intraperitoneal (i.p.) injection, an intragastric (i.g.) inoculation or an oral (p.o.) inoculation of the culture forms, including metacyclic trypomastigotes, of trypanosoma microti, t. evotomys, t. grosi and t. lewisi, respectively. similar levels of parasitaemia were produced by each of the three routes of infection, although the prepatent period was 3-5 days shorter in the ... | 1995 | 8570586 |
| natural babesia infection sought in black and norway rats trapped in five egyptian governorates. | babesiosis is a protozoal disease caused by members of the genus babesia transmitted by the ixodid ticks. it is a parasite of various mammalian hosts as bovine (b. bovis), equine (b. equi), rodent (b. microti), canine (b. canis) and others. human cases of babesiosis have been reported from several countries including egypt. it is now well established that man may become infected (fulminating or subclinical) with several species of babesia without prior splenectomy. in this paper, a total of 398 ... | 1993 | 8376851 |
| identification of membrane-associated proteins in trypanosoma brucei encoding an internal, earlraee amino acid repeat. | differential screening of expression libraries with nonimmune and day 4-6 immune serum from naive rats infected with the protozoan trypanosoma lewisi was used to identify potential cell surface protein coding genes. several t. lewisi cdnas that resulted were partially characterized and used to clone the homologues from trypanosoma brucei. the nucleotide sequence of the cdnas encoding the tb-29 genes of the parasitic protozoan t. brucei obtained by this method (3557 nucleotides for tb-291 and 872 ... | 1994 | 8132566 |
| an unusual morphological type of trypanosoma (herpetosoma) lewisi (kent, 1880) detected in the blood of rattus norvegicus in india. | an unusual morphological type of trypanosoma (herpetosoma) lewisi (kent, 1880) which was detected in rattus norvegicus in india is reported in the present study. this type is different from known types of t. lewisi in that the kinetoplast is at a greater distance from the posterior end (p-k) than the usual type. the total length, including the free flagellum, is 35.3-39.3 microns and p-k is 11.9-15.0 as against total length of 21 to 36.5 microns in the normal form. | 1993 | 8014434 |
| trans-sialidase and sialidase activities discriminate between morphologically indistinguishable trypanosomatids. | the expression of trans-sialidase and sialidase activities in the kinetoplastid protozoa was explored as a potential marker to discriminate between the morphologically indistinguishable flagellates isolated from human, insects and vertebrate reservoir hosts. by virtue of the differences observed in the ratios of these enzyme activities, a collection of 52 species and strains comprising the major taxa of these parasites could be separated into four expression types. type-i parasites express compa ... | 1994 | 7925453 |
| immunoconglutinin and antibody against fibrinogen products in hemolytic anemia and nephritis resulting from infection with a haemobartonella-like agent. | an agent morphologically similar to haemobartonella muris was isolated from the blood of rats infected with a strain of trypanosoma lewisi kept at this department. it caused acute hemolytic anemia, splenomegaly, glomerulonephritis, and death within 5 to 8 days in mature sprague-dawley rats. the disease was less severe in weanling rats which usually recovered within 3 to 4 wk. the anemia was accompanied by phagocytosis of erythrocytes by monocytes of the spleen and bone marrow, by high titers of ... | 1981 | 7264835 |
| [trypanosome sensitivity to polyene antibiotics]. | swelling of the plasma membrane is one of the mechanisms of resistance to damages in pathogenic protozoa. polyenic antibiotics induce reconstruction of the cytoplasma membrane of unicellular eukaryotic organisms, i. e. fungi and protozoa by binding the membrane lipids. the effect of 5 heptaene polyenic antibiotics, such as amphotericin b, mycoheptin, levorin, its sodium salt and levoridone on the growth of trypanosomides of trypanosoma lewisi and crithidia oncopelti was studied. the mic and ic50 ... | 1982 | 7051969 |
| aspects of immunosuppression during plasmodium berghei infection in rats. | depression in immunological responsiveness was manifested in phase with parasitaemia in rats infected with plasmodium berghei. the spleen was the most affected organ. the response of spleen cells to phytohaemagglutinin (pha) and the number of plaque forming cells among spleen cells of rats injected with sheep red blood cells (srbc), were reduced especially at peak parasitaemia. at the onset of the disease the spleen was activated and the responses were amplified. antibody titres in the serum rev ... | 1981 | 7043823 |
| the parasites obtained and bacteria isolated from house rats (rattus rattus linnaeus, 1758) caught in human habitations in ibadan, nigeria. | a total of 169 house rats were killed in different households distributed within five localities of ibadan. a wide range of parasites were encountered. the flea, ceratophylus fasciatus was the commonest ectoparasite found. trichostrongylus columbriformis eggs were the commonest nematode and hymenolepis diminuta the only cestode. escherichia coli was the commonest bacterium found. the incidence of helminthiasis, especially h. diminuta, was generally high among rats trapped in the villages and the ... | 1981 | 7037672 |
| trypanosoma lewisi: enhanced resistance in naive lactating rats and their suckling pups. | 1982 | 7037439 | |
| the trypanosoma lewisi immunofluorescence test: a new simple technique for simultaneous determination of total antinuclear antibodies and the detection of antibodies to double-stranded dna. | an indirect immunofluorescence technique was developed for the detection of antibodies to dsdna and the simultaneous assessment of antinuclear antibodies 'in toto' (ana). this assay was based upon the use as substrate of smears of peripheral blood derived from rats infected with trypanosoma lewisi. t. lewisi possesses a giant kinetoplast posteriorly to the nucleus. enzyme digestion and absorption experiments provided strong evidence that t. lewisi kinetoplast contains dsdna uncontaminated by oth ... | 1982 | 7035570 |
| rheumatoid factor-like immunoglobulin m protects previously uninfected rat pups and dams from trypanosoma lewisi. | the serum of lactating rats that have never been infected with the protozoan parasite trypanosoma lewisi contains a rheumatoid factor-like immunoglobulin m (igm). this igm amplifies a specific immunoglobulin g (igg) response to the parasite and accounts for the unusual resistance of previously uninfected lactating rats and their suckling pups to infection with t. lewisi. a similar rheumatoid factor-like igm, which is induced late in the usual course of infection with t. lewisi in nonlactating ra ... | 1981 | 7025211 |
| the depressed response of spleen cells from rats infected by trypanosoma lewisi in producing a secondary response in vitro to sheep erythrocytes and the ability of soluble products of the trypanosome to induce this depression. | the non-pathogenic trypanosoma lewisi depresses the ability of infected rat spleen cells to respond immunologically to sheep erythrocytes. a study was made to determine whether the parasite would produce this same phenomenon in vitro in marbrook culture vessels with erythrocyte-primed spleen cells from normal rats; the antibody response of the spleen cells was measured by the plaque-forming cell assay. soluble factors from 1 x 10(7) t. lewisi depress the ability of primed cells to form a seconda ... | 1981 | 7019056 |
| [parasite-host relationship specificity in rat trypanosomiasis]. | 1981 | 7015099 | |
| the phospholipases of pathogenic and non-pathogenic trypanosoma species. | four species of trypanosome were examined for phospholipase activities using 1-[3h]palmitoyl-2-acyl-sn-glycero-3-phosphocholine and 1-acyl-2[14c]linoleoyl-sn-glycero-3-phosphocholine as substrates. the major activity in each species is a phospholipase a1 (ec 3.1.1.32) which does not require calcium. the most effective of the detergents tested for activation of the enzyme from each species, and the ph optima, are as follows: trypanosoma brucei, 0.125% triton x-100 at ph 6.0-8.5; t. congolense, 0. ... | 1981 | 7012615 |
| trypanosoma lewisi: avidity and adsorbability of ablastin, the rat antibody inhibiting parasite reproduction. | 1980 | 7000542 | |
| isolation and characterization of pellicular membranes from trypanosoma lewisi bloodstream forms. | 1980 | 6993644 | |
| trypanosoma lewisi: antibody classes which mediate precipitation, agglutination, and the inhibition of reproduction. | 1982 | 6799316 | |
| [proteolytic activity of 4 protozoan species]. | 1981 | 6786380 | |
| a semi-automated microassay method for the measurement of ablastin, a division inhibitory antibody. | division of trypanosoma lewisi in the rat is terminated by ablastin, a factor(s) in the serum of rats acquired during infection which is believed to be specific antibody. in this study a semi-automated microassay technique for the measurement of ablastin is described. the system involved the use of [3h]tdr as a marker for trypanosome division and a multiple-well cell harvester to harvest trypanosomes from wells of microtitre plates. the method is versatile, quantitative and easy to perform, perm ... | 1982 | 6759583 |
| properties of ablastin--a factor in the serum of rats infected with trypanosoma lewisi which inhibits the parasites' division. | the present study investigated the nature of ablastin, a factor present in the serum of rats infected with trypanosoma lewisi and which inhibits the parasites' division. ablastin was unstable to dialysis at ph 1x8, was not adsorbed from serum by trypanosomes and could not be induced in vivo by means other than a natural infection. attempts to purify ablastin from serum by conventional chromatographic techniques were unsuccessful. removal of over 90% of the immunoglobulins from ablastinic serum d ... | 1982 | 6753814 |
| [a new finding on trypanosoma (herpetosoma) forattinii coutinho et pattoli 1964 in the state of são paulo, brazil]. | 1982 | 6753050 | |
| lipopolysaccharide hyperreactivity of animals infected with trypanosoma lewisi or trypanosoma musculi. | rats and mice infected with trypanosoma lewisi and trypanosoma musculi, respectively, showed hyperreactivity to lipopolysaccharide (lps) from gram-negative bacteria. fatal shock could be precipitated with a dose of lps 100 to 1,000 times less in infected compared with noninfected animals. in trypanosome-infected rats and mice, extensive liver damage was evident after lps challenge. these animals showed a pronounced hypoglycemia, marked elevation of blood aspartate transaminase level, and diffuse ... | 1984 | 6500700 |
| trypanosoma lewisi: exoantigen precipitin reactions with antisera from infected and hyperimmune rats. | 1983 | 6402580 | |
| trypanosoma lewisi: in vitro oxygen uptake by parasites grown in albino and black rats. | oxygen consumption of trypanosoma lewisi grown in albino and black rats was measured by the direct method of warburg. respiration rates in buffered ringer's solution, with and without glucose and in normal serum from the respective hosts, were determined for t lewisi grown in albino and black rats. significantly higher respiratory rates were obtained for trypanosomes grown in albino hosts: 31 percent higher in buffered ringer's solution with glucose and 26 percent higher in homologous serum.in t ... | 1984 | 6392572 |
| redescription of the life cycle of trypanosoma (herpetosoma) lewisi from upper egyptian rats. | 1984 | 6392437 | |
| trypanosoma lewisi in field rats and its zoonotic importance. | 1984 | 6389340 | |
| trypanosoma lewisi: the effect of thymectomy on the production of ablastin and the termination of the parasitaemia in infected rats. | this study investigated the effect of the depletion of t lymphocytes on the production of ablastin and the termination of the parasitaemias in porton strain rats infected with trypanosoma lewisi. weanling rats were thymectomised or sham-thymectomised and then x-irradiated. after allowing 96 days for recovery from these procedures the rats were infected with t. lewisi. the rats were considered to be t lymphocyte depleted if they were unable to mount an antibody response to sheep red blood cells b ... | 1984 | 6388547 |
| polyamine oxidase-mediated trypanosome killing: the role of hydrogen peroxide and aldehydes. | trypanosoma lewisi and t. musculi were lysed when incubated with bovine serum in the presence of either spermine or spermidine. similar results were obtained when a fraction from bovine serum containing polyamine oxidase (pao) activity or a commercially available purified beef plasma pao were used in lieu of bovine serum. trypanosomes treated with cytotoxic concentrations of pao-spermine failed to establish infection in rats. these results are similar to those from our previous studies with afri ... | 1984 | 6381596 |
| trypanosoma lewisi: pyruvate and transketolase activity in normal and thiamine deficient rats. | transketolase and pyruvate changes were studied in rats infected with trypanosoma lewisi and fed complete, thiamine-deficient and pair-fed control diets. regardless of the dietary group, marked increases in pyruvate levels were observed in the infected animals. there were no significant differences in erythrocyte transketolase activity of rats given a full complement diet. significant decreases, however, were observed in the transketolase activity of pair-fed and thiamine deficient rats. the gre ... | 1984 | 6381162 |
| interaction between murine natural killer cells and trypanosomes of different species. | the involvement of natural killer (nk) cells in the immunological resistance of mice to murine-specific trypanosoma musculi was evaluated. murine nk cells were found to be unable to kill or inhibit t. musculi or to protect recipients from infection. in addition, the ability of spleen cells from normal mice and from mice on day 3 of t. musculi infection, at the time of maximum nk augmentation, to kill trypanosoma cruzi and trypanosoma lewisi was evaluated. spleen cells from normal mice displayed ... | 1984 | 6370864 |
| isolation of protective antigens from trypanosoma lewisi by using trypanostatic (ablastic) immunoglobulin g from the surface coat. | antigens were purified from extracts of trypanosoma lewisi on immunoadsorbent columns of trypanostatic immunoglobulin g eluted from parasite surface coats at 8 days postinfection. eight absorbed proteins, with molecular weights between 15,000 and 70,000, were identified. these surface coat antigens (scags) were then used to immunize rats. after immunization, sera were assayed in vitro for levels of circulating trypanostatic and trypanocidal antibodies. approximately half of the immune sera had h ... | 1984 | 6363294 |
| externally disposed membrane polypeptides of intact and protease-treated trypanosoma lewisi correlated with sensitivity to alternate complement pathway-mediated lysis. | reproducing forms of trypanosoma lewisi isolated from x-irradiated rats and adult forms from intact rats were not lysed by fresh mammalian sera. treating parasites with trypsin or chymotrypsin, but not with neuraminidase, under conditions which did not impair viability rendered the parasites sensitive to lysis by rat, mouse, rabbit, and human sera. serum from animal strains or humans genetically deficient in complement component c3, c5, or c6 did not lyse protease-treated parasites. the lytic fa ... | 1983 | 6358042 |
| anemia and thrombocytopenia from corynebacterium parvum-stimulated resistance against malaria, trypanosomiasis, and babesiosis. | nonspecific immunity (nsi) was manifested in rats injected intravenously with killed corynebacterium parvum and challenged with trypanosoma lewisi, plasmodium chabaudi, or babesia rodhaini. the nsi became evident some 5 days after infection as a suppressed parasitemia, a more rapid recovery from patent infection and as enhanced survival among rats infected with b. rodhaini. the c. parvum injections produced anemia and thrombocytopenia with splenomegaly and signs of glomerulonephritis in rats. th ... | 1983 | 6355427 |
| the glycoproteins of the complex surface coat of trypanosoma lewisi. | blood stream forms of trypanosoma lewisi from rats previously infected were labelled in vitro by galactose-oxidase oxidation followed by nab3h4 reduction and subjected to 7.5% sds-polyacrylamide gel analysis, by this procedure 8 bands were detected on sds polyacrylamide gel electrophoresis. we conclude that surface composition of trypanosoma lewisi resulted more complex than that of trypanosoma so far studied, suggesting a possible relation with induced immunity and reduced ability of the parasi ... | 1983 | 6354473 |
| rat liver glucose-6-phosphate dehydrogenase isozymes: influence of infection with trypanosoma. | glucose-6-phosphate dehydrogenase (g6pd) changes were studied in livers of rats inoculated with trypanosoma lewisi, trypanosoma rhodesiense, trypanosoma congolense and trypanosoma brucei. marked increases in g6pd were directly related to the degree of parasitemia. no essential differences in g6pd levels were seen in animals inoculated with physiological saline when compared with uninoculated controls. elevation of g6pd was observed only from day 10 to 20 in rats inoculated with t. lewisi. after ... | 1983 | 6349921 |
| the effect of splenectomy on the production of ablastin and the termination of the parasitaemia in rats infected with trypanosoma lewisi. | this study investigated the effect of splenectomy on the production of ablastin and the elimination of trypanosoma lewisi from the circulation of infected porton rats. rats were splenectomized or sham-splenectomized either before or at various stages during the infection and the course of the parasitaemia compared with untreated control animals. ablastin titres in the serum were measured by a sensitive in vitro assay and were found to be the same in all the rats, regardless of the nature or timi ... | 1983 | 6349598 |
| effect of splenectomy on trypanosoma lewisi infection in young rats. | the effect of splenectomy on animals infected with trypanosoma lewisi is unclear, and previous reports are inconclusive or conflictive. we splenectomized rats of different ages after they had been infected with t. lewisi. female sprague-dawley rats, hemobartonella-free, were assigned to four groups according to weight: 80, 108, 140, and 170 g. each group had splenectomized, sham-operated, and nonoperated control subgroups, all infected with t. lewisi (0.5 ml of 10(6) parasites per ml) 90 h befor ... | 1983 | 6343240 |
| cultivation of the rodent trypanosomes, trypanosoma lewisi and t. musculi, in chick embryos. | 1983 | 6338195 | |
| basis of the specificity of rodent trypanosomes for their natural hosts. | the strong natural insusceptibility of mice to infection with the rat-specific trypanosoma lewisi was investigated in a variety of mouse strains. parasite elimination by all strains was similar involving a lag phase of about 7 h of constant parasitemia followed by rapid clearance (half-times of 55 and 130 min in different strains). in vitro cultures were utilized to determine whether mouse cells and serum were inherently deficient in supporting t. lewisi or, alternatively, toxic for the parasite ... | 1981 | 6268542 |
| studies on glycerol kinase and its role in atp synthesis in trypanosoma brucei. | glycerol kinase of trypanosoma brucei has been shown to be capable of catalysing sn-glycerol-3-phosphate dependent adp phosphorylation for atp generation. the rate of this reaction (vr) is sufficient to account for the observed rate of glycerol production from anaerobic glucose metabolism by intact cells and to account for net atp synthesis. glycerol kinase has been purified by preparing a post-nuclear, particulate fraction and solubilizing the enzyme with 0.5% (w/v) triton x-100. this treatment ... | 1980 | 6258071 |
| molecular cloning of the "minor" component of the kinetoplast dna of trypanosoma lewisi. | kinetoplast dna was cloned in the pbr322 plasmid using the bamhi site. in situ hybridization of iodinated recombinant dna showed hybridization grains only in the kinetoplast region. the recombinant dna was analyzed with restriction enzymes and its base ratio was determined by analytical cscl density gradient. | 1980 | 6257401 |
| correlation of oligomycin-sensitive atpase activity in trypanosomes with their content of an antigen to primary biliary cirrhosis. | the amounts of an antigen to primary biliary cirrhosis (pbc) which occur in subcellular fractions of trypanosoma rhodesiense and t. lewisi correlate positively with the oligomycin-sensitive (os) atpase activity of these fractions. this result is consistent with the mitochondrial atpase association of the antigen in mammalian and other cells. higher levels of os-atpase and of pbc antigen in t. lewisi accord with a more extensive mitochondrial development in this species. | 1984 | 6239698 |
| trypanostatic activity of rat igg purified from the surface coat of trypanosoma lewisi. | host igg is a component of the surface coat of trypanosoma lewisi; it is specifically acquired during infection in the rat, concomitant with a rise in titer of trypanostatic (ablastic) activity of host serum. host igg was eluted from trypomastigotes at 7 to 9 days postinfection with a high salt-low ph buffer. surface coats and trypanosome ultrastructure were not notably altered by the elution procedure, as determined by electron microscopy. rat igg was removed and purified from the trypanosome e ... | 1982 | 6182278 |
| two identical symmetrical regions in the minicircle structure of trypanosoma lewisi kinetoplast dna. | two minicircles of trypanosoma lewisi kinetoplast dna, linearized by different restriction enzymes, have been cloned in m13 derivative vectors. their nucleotide sequences share a dna fragment which accounts for 10% of the minicircle total length. this highly conserved region (constant region) is present twice within the same minicircle in a direct orientation and in an almost symmetrical location. comparison of the t. lewisi constant region with those of t. brucei and t. equiperdum shows identic ... | 1984 | 6096711 |
| host serum malic dehydrogenase activity associated with trypanosoma lewisi infection. | 1967 | 6027419 | |
| phospholipids of trypanosoma lewisi, t. vivax, t. congolense, and t. brucei. | 1967 | 6026221 | |
| virulent trypanosoma lewisi infections in cortisone-treated rats. | 1967 | 6022387 | |
| oxygen uptake by trypanosoma lewisi complex cells. 3. c isolate. | 1966 | 5943918 | |
| a trypanosoma lewisi-like organism from the rabbit, sylvilagus floridanus, in virginia. | 1966 | 5942537 | |
| oxygen uptake by trypanosoma lewisi-complex cells. ii. r and l isolates compared. | 1966 | 5940094 | |
| serum transaminases and aldolase in rats inoculated with trypanosoma lewisi. | 1966 | 5933980 | |
| development of trypanosoma lewisi in experimental chimaeras. | 1969 | 5806200 | |
| comparative immunological studies on somatic antigens and secretion-excretion products of blood stream and culture forms of trypanosoma lewisi. i. protective immunity and the agglutinin response. | 1969 | 5795103 | |
| the attachment of trypanosoma lewisi in the rectum of its vector flea nosopsyllus fasciatus. | 1969 | 5789066 | |
| [immunological relations between trypanosoma cruzi and trypanosoma lewisi]. | 1969 | 5788822 | |
| comparative studies on blood stream and culture forms of trypanosoma lewisi. i. oxygen utilization, carbon dioxide production and glucose uptake. | 1969 | 5788607 | |
| carbohydrate transport in trypanosoma lewisi. | 1969 | 5778271 | |
| the fine-structure of the epimastigote forms of trypanosoma lewisi in the rectum of the flea, nosopsyllus fasciatus. | 1969 | 5769498 | |
| [on the host specificity of trypanosoma lewisi infection]. | 1968 | 5719578 | |
| comparison of mitochondrial enzymes between young and adult forms of trypanosoma lewisi. | 1968 | 5719060 | |
| [behavior of iron in the blood in experimental infection with trypanosoma lewisi]. | 1968 | 5715932 | |
| [behavior of serum copper in rats during experimental infection with trypanosoma lewisi]. | 1968 | 5715931 | |
| [behavior of the blood mucoproteins in rats infected with trypanosoma lewisi]. | 1968 | 5715925 | |
| the effects of pantothenic acid, pantoyltaurine, salicylate and related compounds on the in vitro and in vivo growth of trypanosoma lewisi. | 1968 | 5710274 | |
| [studies on the experimental infection with trypanosoma lewisi in mice]. | 1968 | 5707633 | |
| growth and immunologic studies on the culture forms of trypanosoma lewisi. | 1968 | 5703435 | |
| mechanical transmission of trypanosoma lewisi (kinetoplastida: trypanosomidae) by rhodnius prolixus (hemiptera: reduviidae). | 1968 | 5699976 | |
| fine structure and replication of the kinetoplast of trypanosoma lewisi. | the kinetoplastic dna of trypanosoma lewisi is described as a filamentous body lying within a mitochondrion, with the filaments oriented parallel to the long axis of the cell. the manner of fixation, the replicative state, and perhaps the physiological state of the cell, may result in slight morphological differences among such bodies. the kinetoplastic dna replicates to form "left" and "right" rather than "upper" and "lower" members, and both the kinetoplast and nucleus incorporate radiothymidi ... | 1968 | 5677967 |
| trypanosoma lewisi infections in normal rats and in rats treated with dexamethasone. | 1968 | 5643477 | |
| trypanosoma lewisi: physiologic adaptation of wild isolate to albino rats evidenced by cell populations and respiratory activity. | 1971 | 5556286 | |
| kinetoplast deoxyribonucleic acid of the hemoflagellate trypanosoma lewisi. | cesium chloride centrifugation of dna extracted from cells of blood strain trypanosoma lewisi revealed a main band, rho = 1.707, a light satellite, rho = 1.699, and a heavy satellite, rho = 1.721. culture strain t. lewisi dna comprised only a main band, rho = 1.711, and a light satellite, rho = 1.699. dna isolated from dnase-treated kinetoplast fractions of both the blood and culture strains consisted of only the light satellite dna. electron microscope examination of rotary shadowed preparation ... | 1970 | 5497546 |
| effect of holothurin on trypanosoma lewisi infections in rats. | 1970 | 5449233 |