Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| structural and genetic characterization of the o-antigen of enterobacter cloacae c5529 related to the o-antigen of e. cloacae g3054. | on mild acid degradation of the lipopolysaccharide of enterobacter cloacae c5529, the o-polysaccharide chain was cleaved at the linkages of 5,7-diacetamido-3,5,7,9-tetradeoxy-l-glycero-l-manno-non-2-ulosonic acid (di-n-acetylpseudaminic acid, psep5ac7ac). the resultant oligosaccharide and an alkali-treated lipopolysaccharide were studied by sugar analysis along with (1)h and (13)c nmr spectroscopy, and the following structure of the tetrasaccharide repeating unit of the o-polysaccharide was esta ... | 2017 | 28342969 |
| two-year follow-up outcomes of premature infants enrolled in the phase i trial of mesenchymal stem cells transplantation for bronchopulmonary dysplasia. | to determine the long-term safety and outcomes of mesenchymal stem cells (mscs) for bronchopulmonary dysplasia in premature infants enrolled in a previous phase i clinical trial up to 2 years of corrected age (ca). | 2017 | 28341525 |
| high prevalence of non-clonal imipenem-nonsusceptible enterobacter spp. isolates in korea and their association with porin down-regulation. | we investigated the prevalence and clonal distribution of imipenem-nonsusceptible enterobacter clinical isolates from hospitals in korea and the contributions of various mechanisms to imipenem nonsusceptibility. the in vitro antimicrobial susceptibility to imipenem of 357 non-duplicated enterobacter isolates obtained from eight geographically distant tertiary care hospitals in korea was evaluated. imipenem-nonsusceptible enterobacter isolates were genotyped. additionally, β-lactamase genes were ... | 2017 | 28336135 |
| multiregional dissemination of kpc-producing klebsiella pneumoniae st258/st512 genotypes in poland, 2010-14. | in 2008-09, the kpc carbapenemase epidemiology in poland was dominated by a klebsiella pneumoniae st258 kpc-2 outbreak in warsaw and its administrative region. the aim of this study was to analyse the situation in 2010-14, with a focus on new outbreaks in other parts of the country. | 2017 | 28333331 |
| phytases from enterobacter and serratia species with desirable characteristics for food and feed applications. | phytases are enzymes of great industrial importance with wide range of applications in animal and human nutrition. these catalyze the hydrolysis of phosphomonoester bonds in phytate, thereby releasing lower forms of myo-inositol phosphates and inorganic phosphate. addition of phytase to plant-based foods can improve its nutritional value and increase mineral bioavailability by decreasing nutritional effect of phytate. in the present investigation, 43 phytase positive bacteria on psm plates were ... | 2016 | 28330134 |
| soft tissue infections from fish spike wounds: normal commensal bacteria are more common than marine pathogens. | a fish spike injury can be sustained by anyone handling fish; during fishing, meal preparation or in retail. case reports of fish spikes inoculating victims with virulent marine-specific pathogens and causing systemic illness led us to question whether empirical treatment of these injuries with amoxicillin and clavulanic acid is adequate. | 2017 | 28320052 |
| screening for fecal carriage of mcr-producing enterobacteriaceae in healthy humans and primary care patients. | the extent of the occurrence of the plasmid-encoded colistin resistance genes mcr-1 and mcr-2 among humans is currently sparsely studied in western europe. | 2017 | 28316780 |
| bacteria associated with four species of dacus (diptera: tephritidae) and their role in the nutrition of the larvae. | the bacteria associated with dacus tryoni (froggatt), dacus jarvisi (tryon), dacus neohumeralis (hardy) and dacus cacuminatus (hering) were examined. bacteria were isolated from the surface of freshly-laid eggs, from within surface sterilised pupae, from heads and abdomens of wild and laboratory-maintained flies, and from decomposed fruits in which the wild larvae were feeding. a more diverse flora was associated with d. tryoni and d. jarvisi (15 and 14 species, respectively) than with d. neohum ... | 1985 | 28311582 |
| ulcerative granuloma of the eyelid as the initial manifestation of granulomatosis with polyangiitis (wegener's granulomatosis): a case report. | a 56-year-old-man presented a 2-month history of chalazion in the eyelids without response to treatment and with an inconclusive biopsy. laboratory results confirmed the presence of enterobacter cloacae and streptococcus gordonii infection. despite appropriate intravenous antibiotic treatment, clinical worsening was observed. radical surgical excision and total tarsorrhaphy were performed. following treatment, the patient was asymptomatic for 6 weeks until he developed acute renal failure, gener ... | 2017 | 28306365 |
| in vitro activity of imipenem against carbapenemase-positive enterobacteriaceae: smart global surveillance program 2008-2014. | the study for monitoring antimicrobial resistance trends (smart) global surveillance program collected 103,960 isolates of enterobacteriaceae from 2008 to 2014. from this isolate collection all ertapenem-non-susceptible isolates (mic, ≥1 μg/ml; n = 3,428) and 9,371 isolates of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, and proteus mirabilis with an ertapenem-susceptible extended-spectrum β-lactamase (esbl)-positive phenotype were assessed for the presence of common carbapenemas ... | 2017 | 28298454 |
| simplified and representative bacterial community of maize roots. | plant-associated microbes are important for the growth and health of their hosts. as a result of numerous prior studies, we know that host genotypes and abiotic factors influence the composition of plant microbiomes. however, the high complexity of these communities challenges detailed studies to define experimentally the mechanisms underlying the dynamics of community assembly and the beneficial effects of such microbiomes on plant hosts. in this work, from the distinctive microbiota assembled ... | 2017 | 28275097 |
| does second place count? lessons from a major discrepancy between carbapenem-resistant klebsiella pneumoniae and carbapenem-resistant enterobacter cloacae in a one-year follow-up study. | 2017 | 28260534 | |
| in vitro activity of ceftaroline and comparator agents against gram-positive and gram-negative clinical isolates from cancer patients. | bacterial infections are common in cancer patients. ceftaroline (cft) is a broad-spectrum cephalosporin with activity against most gram-positive organisms (gpos) and many gram-negative organisms. in this study, the in vitro activity of cft was compared with vancomycin (van), daptomycin (dap), linezolid (lzd), trimethoprim/sulphamethoxazole (sxt) and tigecycline (tig) against bacteria (predominantly blood culture isolates) isolated from cancer patients in 2014 and 2015. cft was active against met ... | 2017 | 28257904 |
| human norovirus binding to select bacteria representative of the human gut microbiota. | recent reports describe the ability of select bacterial strains to bind human norovirus, although the specificity of such interactions is unknown. the purpose of this work was to determine if a select group of bacterial species representative of human gut microbiota bind to human norovirus, and if so, to characterize the intensity and location of that binding. the bacteria screened included naturally occurring strains isolated from human stool (klebsiella spp., citrobacter spp., bacillus spp., e ... | 2017 | 28257478 |
| analysis of microbial diversity in shenqu with different fermentation times by pcr-dgge. | shenqu is a fermented product that is widely used in traditional chinese medicine (tcm) to treat indigestion; however, the microbial strains in the fermentation process are still unknown. the aim of this study was to investigate microbial diversity in shenqu using different fermentation time periods. dgge (polymerase chain reaction-denaturing gradient gel electrophoresis) profiles indicated that a strain of pediococcus acidilactici (band 9) is the predominant bacteria during fermentation and tha ... | 2017 | 28256389 |
| new mouse model for chronic infections by gram-negative bacteria enabling the study of anti-infective efficacy and host-microbe interactions. | only a few, relatively cumbersome animal models enable long-term gram-negative bacterial infections that mimic human situations, where untreated infections can last for weeks. here, we describe a simple murine cutaneous abscess model that enables chronic or progressive infections, depending on the subcutaneously injected bacterial strain. in this model, pseudomonas aeruginosa cystic fibrosis epidemic isolate lesb58 caused localized high-density skin and soft tissue infections and necrotic skin l ... | 2017 | 28246361 |
| very high prevalence of extended-spectrum beta-lactamase-producing enterobacteriaceae in bacteriemic patients hospitalized in teaching hospitals in bamako, mali. | the worldwide dissemination of extended-spectrum beta-lactamase producing enterobacteriaceae, (esbl-e) and their subset producing carbapenemases (cpe), is alarming. limited data on the prevalence of such strains in infections from patients from sub-saharan africa are currently available. we determined, here, the prevalence of esbl-e/cpe in bacteriemic patients in two teaching hospitals from bamako (mali), which are at the top of the health care pyramid in the country. during one year, all entero ... | 2017 | 28245252 |
| aerobic and heterotrophic nitrogen removal by enterobacter cloacae cf-s27 with efficient utilization of hydroxylamine. | heterotrophic bacterium, enterobacter cloacae cf-s27 exhibited simultaneous nitrification and aerobic denitrification in presence of high concentration of hydroxylamine. with the initial nitrogen concentration of 100mgl(-1)h(-1), ammonium, nitrate and nitrite removal efficiencies were 81%, 99.9% and 92.8%, while the corresponding maximum removal rates reached as high as 11.6, 15.1 and 11.2mgl(-1)h(-1) respectively. quantitative amplification by real time pcr and enzyme assay demonstrated that hy ... | 2017 | 28242385 |
| enterobacter cloacae complex isolates harboring blanmc-a or blaimi-type class a carbapenemase genes on novel chromosomal integrative elements and plasmids. | carbapenem-resistant enterobacter cloacae complex isolates submitted to a reference laboratory from 2010 to 2015 were screened by pcr for seven common carbapenemase gene groups, namely, kpc, ndm, oxa-48, vim, imp, ges, and nmc-a/imi. nineteen of the submitted isolates (1.7%) were found to harbor ambler class a blanmc-a or blaimi-type carbapenemases. all 19 isolates were resistant to at least one carbapenem but susceptible to aminoglycosides, trimethoprim-sulfamethoxazole, tigecycline, and ciprof ... | 2017 | 28223374 |
| enumeration and identification of coliform bacteria injured by chlorine or fungicide mixed with agricultural water. | chemical sanitizers may induce no injury (bacteria survive), sublethal injury (bacteria are injured), or lethal injury (bacteria die). the proportion of coliform bacteria that were injured sublethally by chlorine and fungicide mixed with agricultural water (pond water), which was used to dilute the pesticide solution, was evaluated using the thin agar layer (tal) method. in pure cultures of enterobacter cloacae , escherichia coli , and e. coli o157:h7 (representing a human pathogen), the percent ... | 2016 | 28221856 |
| prevalence, antibiotic susceptibility and characterization of antibiotic resistant genes among carbapenem-resistant gram-negative bacilli and yeast in intestinal flora of cancer patients in north lebanon. | the emergence and spread of carbapenem-resistant bacteria are a significant clinical and public health concern. the aim of the study is to determine the prevalence of intestinal carriage of carbapenem-resistant bacteria and yeasts in cancer patients under chemotherapy. 41 stool samples collected from cancer patients in nini hospital in tripoli, north lebanon have been analyzed. after isolating yeasts and carbapenem-resistant bacteria, a biochemical identification and antimicrobial susceptibility ... | 2017 | 28216021 |
| the locus of heat resistance (lhr) mediates heat resistance in salmonella enterica, escherichia coli and enterobacter cloacae. | enterobacteriaceae comprise food spoilage organisms as well as food-borne pathogens including escherichia coli. heat resistance in e. coli was attributed to a genomic island called the locus of heat resistance (lhr). this genomic island is also present in several other genera of enterobacteriaceae, but its function in the enteric pathogens salmonella enterica and enterobacter cloacae is unknown. this study aimed to determine the frequency of the lhr in food isolates of e. coli, and its influence ... | 2017 | 28213040 |
| oxa-48-like carbapenemases in the uk: an analysis of isolates and cases from 2007 to 2014. | oxa-48-like carbapenemases have spread worldwide since 2001. we analysed patient and microbiological data for uk isolates with these enzymes as confirmed by the national reference laboratory from november 2007 to december 2014. | 2017 | 28199647 |
| antibacterial effect of sevoflurane and isoflurane. | multidrug resistant bacteria are increasing worldwide and therapeutic options are limited. some anaesthetics have shown antibacterial activity before. in this study, we have investigated the antibacterial effect of the halogenated anaesthetic agents sevoflurane and isoflurane against a range of resistant pathogens. | 2017 | 28198170 |
| the overproduction of indole-3-acetic acid (iaa) in endophytes upregulates nitrogen fixation in both bacterial cultures and inoculated rice plants. | endophytic bacteria from roots and leaves of rice plants were isolated and identified in order to select the diazotrophs and improve their nitrogen-fixing abilities. the nitrogen-fixing endophytes were identified by pcr amplification of the nifh gene fragment. for this purpose, two isolates, enterobacter cloacae rca25 and klebsiella variicola rca26, and two model bacteria (herbaspirillum seropedicae z67 and sinorhizobium fredii ngr234) were transformed to increase the biosynthesis of the main pl ... | 2017 | 28197647 |
| molecular characteristics of carbapenem-resistant enterobacter cloacae in ningxia province, china. | the emergence of carbapenem-resistant enterobacteriaceae (cre) has become a major public health concern worldwide and a new challenge in the treatment of infectious diseases. the molecular characteristics of enterobacter cloacae in ningxia china are unknown. in this study, we reported 10 carbapenem-resistant e. cloacae isolates from the general hospital of ningxia medical university, the largest university hospital in ningxia between january 2012 and december 2013. bacteria isolates were identif ... | 2017 | 28197140 |
| in vitro screening of an fda-approved library against eskape pathogens. | bacterial resistance to conventional antibiotics is an increasingly serious threat to public health worldwide that requires immediate exploration and the development of novel antimicrobial compounds. drug repurposing is an inexpensive and untapped source of new antimicrobial leads, and it holds many attractive features warranting further attention for antimicrobial drug discovery. in an effort to repurpose drugs and explore new leads in the field of antimicrobial drug discovery, we performed a w ... | 2017 | 28190396 |
| identification and whole genome sequencing of the first case of kosakonia radicincitans causing a human bloodstream infection. | the taxonomy of enterobacter species is rapidly changing. herein we report a bloodstream infection isolate originally identified as enterobacter cloacae by vitek2 methodology that we found to be kosakonia radicincitans using genetic means. comparative whole genome sequencing of our isolate and other published kosakonia genomes revealed these organisms lack the ampc β-lactamase present on the chromosome of enterobacter sp. a fimbriae operon primarily found in escherichia coli o157:h7 isolates was ... | 2017 | 28174569 |
| global molecular epidemiology of imp-producing enterobacteriaceae. | international data on the molecular epidemiology of enterobacteriaceae with imp carbapenemases are lacking. we performed short-read (illumina) whole-genome sequencing on a global collection of 38 imp-producing clinical enterobacteriaceae (2008 to 2014). imp-producing enterobacteriaceae (7 varieties within 11 class 1 integrons) were mainly present in the south pacific and asia. specific blaimp-containing integrons (in809 with blaimp-4, in722 with blaimp-6, and in687 with blaimp-14) were circulati ... | 2017 | 28167555 |
| molecular epidemiology of carbapenemase-producing enterobacteriaceae in a primary care hospital in japan, 2010-2013. | recently, carbapenemase-producing enterobacteriaceae (cpe) have been spreading worldwide and have become a threat in healthcare systems. we investigated the isolation frequency and molecular epidemiological characteristics of cpe isolated from clinical samples collected at a primary care hospital over the four years of 2010-2013 in japan. cpe were detected in 17 (0.34%) of 4875 isolates by the broth microdilution method, sodium mercaptoacetate inhibition test, and modified hodge test using merop ... | 2017 | 28161293 |
| factors associated with carriage of carbapenem-non-susceptible enterobacteriaceaein north-eastern france and outcomes of infected patients. | carbapenems are frequently used as a last resort to treat infections caused by multidrug-resistant gram-negative organisms, thus carbapenem-non-susceptible enterobacteriaceae (cnse) is an emerging health threat. | 2017 | 28158526 |
| prevalence of antibacterial resistant bacterial contaminants from mobile phones of hospital inpatients. | mobile phones contaminated with bacteria may act as fomites. antibiotic resistant bacterial contamination of mobile phones of inpatients was studied. one hundred and six samples were collected from mobile phones of patients admitted in various hospitals in jazan province of saudi arabia. eighty-nine (83.9%) out of 106 mobile phones were found to be contaminated with bacteria. fifty-two (49.0%) coagulase-negative staphylococcus, 12 (11.3%) staphylococcus aureus, 7 (6.6%) enterobacter cloacae, 3 ( ... | 2014 | 28156258 |
| potency and selectivity indices of acetone leaf extracts of nine selected south african trees against six opportunistic enterobacteriaceae isolates from commercial chicken eggs. | the rise in antimicrobial resistance in a plethora of nosocomial and opportunistic bacterial pathogens often isolated from commercial eggs, poses a serious public health concern. the existence of these contaminants may also serve as a drawback in the current efforts of improving the well-being of immunocompromised patients. the aim of this study was to determine the efficacy of plant extracts that had good activity on escherichia coli in previous word on pathogens isolated from eggs for possible ... | 2017 | 28148263 |
| enantio convergent biotransformation of o,o-dimethyl-4-oxoazetidin-2-ylphosphonate using fungal cells of penicillium minioluteum and purified enzymes. | this report presents the bioconversion of o,o-dimethyl-4-oxoazetidin-2-ylphosphonate 1 performed in two ways: with the enzymatic system of p. minioluteum and with the application of purified enzymes: penicillinase and two proteases of different origin. recorded nmr spectra allowed confirming the reaction progress and also postulating possible mechanism of conversion. the path of bioconversion was defined as enantio convergent process for both modes of applied biocatalysts. this means that kineti ... | 2017 | 28143659 |
| prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive enterobacteriaceae in patients and healthy adults from china: an epidemiological and clinical study. | the mcr-1 gene confers transferable colistin resistance. mcr-1-positive enterobacteriaceae (mcrpe) have attracted substantial medical, media, and political attention; however, so far studies have not addressed their clinical impact. herein, we report the prevalence of mcrpe in human infections and carriage, clinical associations of mcr-1-positive escherichia coli (mcrpec) infection, and risk factors for mcrpec carriage. | 2017 | 28139431 |
| prospective surveillance of healthcare associated infections in a cambodian pediatric hospital. | healthcare associated infections (hai) are the most common preventable adverse events following admission to healthcare facilities. data from low-income countries are scarce. we sought to prospectively define hai incidence at angkor hospital for children (ahc), a cambodian pediatric referral hospital. | 2017 | 28138385 |
| development of multiple cross displacement amplification label-based gold nanoparticles lateral flow biosensor for detection of listeria monocytogenes. | listeria monocytogenes, one of most problematic foodborne pathogens, is responsible for listeriosis in both humans and animals and mainly transmitted through the food chain. in this report, we propose a simple, rapid, and nearly instrument-free molecular technique using multiple cross displacement amplification (mcda) label-based gold nanoparticles lateral flow biosensor (lfb) for specific, sensitive, and visual detection of l. monocytogenes. the mcda-lfb method was carried out at a constant tem ... | 2017 | 28138243 |
| use of colistin in a neonatal intensive care unit: a cohort study of 65 patients. | background the emergence of infections related to multidrug-resistant gram-negative bacilli (mdr-gnb) reintroduced the use of colistin, an antibiotic that was previously abandoned due to adverse effects. however, because of its limited use in neonatal intensive care units, there is very little data about the effectiveness and safety of colistin in children and newborns. in this study, which will be the largest case study in the literature, we aimed to evaluate the effectiveness and safety of col ... | 2017 | 28135233 |
| the essential oil from the fruits of the brazilian spice xylopia sericea a. st.-hil. presents expressive in-vitro antibacterial and antioxidant activity. | the aims of this study were to investigate the chemical composition and the antioxidant activity and antibacterial activity of the essential oil of xylopia sericea fruits (oxs). the fruits of this species are popularly used for medicinal purposes, and as a condiment in food preparation. | 2017 | 28134988 |
| [profile of bacterial resistance in pediatric urinary tract infections in 2014]. | in pediatric units, bacteria-producing extended-spectrum-betalactamase (esbl) have an increasing prevalence among bacteria causing febrile urinary tract infections (utis). the purpose of this study was to evaluate the epidemiology of bacteria resistance patterns observed in utis, in order to assess the current antibiotic treatment protocols. this study is based upon a single-center retrospective chart review of the cytobacteriological urine cultures performed in utis between 1 january and 31 dec ... | 2017 | 28131557 |
| risk factors for relapse or persistence of bacteraemia caused by enterobacter spp.: a case-control study. | enterobacter spp. possess chromosomal ampc beta-lactamases that may be expressed at high levels. previous studies have demonstrated a risk of relapsed bacteraemia following therapy with third generation cephalosporins (3gcs). what additional factors predict microbiological failure in enterobacter bacteraemia is unclear. we aimed to determine factors associated with microbiological failure in enterobacter bacteraemia. | 2017 | 28127422 |
| global assessment of the activity of tigecycline against multidrug-resistant gram-negative pathogens between 2004 and 2014 as part of the tigecycline evaluation and surveillance trial. | multidrug-resistant (mdr) gram-negative organisms are a burden on the global health care system. the tigecycline evaluation and surveillance trial (test) is an ongoing global study designed to monitor the in vitro activities of tigecycline and a panel of marketed antimicrobials against a range of clinically significant pathogens. in this study, in vitro data are presented for mdr acinetobacter baumannii, pseudomonas aeruginosa, escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, enterob ... | 2017 | 28124025 |
| effect of preoperative biliary drainage on bacterial flora in bile of patients with periampullary cancer. | patients with obstructive jaundice due to periampullary tumours may undergo preoperative biliary drainage (pbd). the effect of pbd on the microbiome of the biliary system and on postoperative outcome remains unclear. | 2017 | 28121036 |
| optimization of enterobacter cloacae (ku923381) for diesel oil degradation using response surface methodology (rsm). | efficiency of enterobacter cloacae ku923381 isolated from petroleum hydrocarbon contaminated soil was evaluated in batch culture and bioreactor mode. the isolate were screened for biofilm formation using qualitative and quantitative assays. response surface methodology (rsm) was used to study the effect of ph, temperature, glucose concentration, and sodium chloride on diesel degradation. the predicted values for diesel oil degradation efficiency by the statistical designs are in a close agreemen ... | 2017 | 28120192 |
| whole genome sequencing reveals high-resolution epidemiological links between clinical and environmental klebsiella pneumoniae. | klebsiella pneumoniae is a gram-negative bacterial species capable of occupying a broad range of environmental and clinical habitats. known as an opportunistic pathogen, it has recently become a major causative agent of clinical infections worldwide. despite growing knowledge about the highly diverse population of k. pneumoniae, the evolution and clinical significance of environmental k. pneumoniae, as well as the relationship between clinical and environmental k. pneumoniae, are poorly defined. | 2017 | 28118859 |
| bioadsorption and biostabilization of cadmium by enterobacter cloacae tu. | biostabilization of cadmium, a hazardous chemical found widely in china, was attempted using enterobacter cloacae tu (e.cloacae tu). a cadmium (cd)-tolerant e.cloacae tu was obtained by mutagenesis using an atmosphere pressure glow discharge plasma system, and it displayed regular growth behavior in the presence of 250 mg/l cd in solution. the maximum stabilization capacity of e.cloacae tu toward cd reached 67.0 ± 3.5 mg/g dry cell weight at an initial cd concentration of 200 mg/l. the percentag ... | 2017 | 28117094 |
| comparison of 16s ribosomal rna gene sequence analysis and conventional culture in the environmental survey of a hospital. | nosocomial infection is one of the most common complications within health care facilities. certain studies have reported outbreaks resulting from contaminated hospital environments. although the identification of bacteria in the environment can readily be achieved using culturing methods, these methods detect live bacteria. sequencing of the 16s ribosomal rna (16s rrna) gene is recognized to be effective for bacterial identification. in this study, we surveyed wards where drug-resistant bacteri ... | 2017 | 28116119 |
| induced membrane technique for the treatment of chronic hematogenous tibia osteomyelitis. | chronic hematogenous osteomyelitis often results from the improper treatment of acute hematogenous osteomyelitis. at present, there is lack of uniform standards for the treatment, and the clinical features of the disease are unclear. the purpose of this study was to explore the clinical efficacy and complications of chronic hematogenous tibia osteomyelitis treated with the induced membrane technique. | 2017 | 28114929 |
| fungal periprosthetic joint infection following total elbow arthroplasty: a case report and review of the literature. | with improving surgical techniques for total elbow arthroplasty clinical outcomes have improved and its utilization continues to increase. despite these advances, complication rates remain as high as 24%. of these complications periprosthetic joint infection is one of the most common and morbid. the rheumatoid elbow remains a leading indication for total elbow arthroplasty. patients with this condition frequently require immunosuppressive therapy, which places them at higher risk of both typical ... | 2017 | 28109195 |
| in vitro susceptibility to 19 agents other than β-lactams among third-generation cephalosporin-resistant enterobacteriaceae recovered on hospital admission. | as part of the multicentre antibiotic therapy optimisation study, mic values of 19 non-β-lactam agents were determined for third-generation cephalosporin-resistant escherichia coli, klebsiella species and enterobacter species (3gcreb) isolates collected in german hospitals. | 2017 | 28108677 |
| pitfalls in interpretation of fdg pet/ct: septic pulmonary emboli mimicking metastases in a case of gastric carcinoma. | inflammatory lesions may sometimes show intense tracer uptake and mimic neoplastic lesions on (18) f-fluoro-deoxyglucose (fdg) positron emission tomography/computed tomography (pet/ct). we report one such false positive case on fdg pet/ct, where septic pulmonary emboli (spe) mimicked pulmonary metastases. a 45-year-old man with stomach cancer had an indwelling central venous catheter (cvc) in situ while on neoadjuvant chemotherapy. he underwent fdg pet/ct scan for response assessment and the ima ... | 2016 | 28104952 |
| antimicrobial activity, ame resistance, and a-site binding studies of anthraquinone-neomycin conjugates. | the antibacterial effects of aminoglycosides are based on their association with the a-site of bacterial rrna and interference with the translational process in the bacterial cell, causing cell death. the clinical use of aminoglycosides is complicated by resistance and side effects, some of which arise from their interactions with the human mitochondrial 12s rrna and its deafness-associated mutations, c1494u and a1555g. we report a rapid assay that allows screening of aminoglycoside compounds to ... | 2017 | 28103015 |
| evaluation of three sample preparation methods for the direct identification of bacteria in positive blood cultures by maldi-tof. | patient mortality is significantly reduced by rapid identification of bacteria from sterile sites. maldi-tof can identify bacteria directly from positive blood cultures and multiple sample preparation methods are available. we evaluated three sample preparation methods and two maldi-tof score cut-off values. positive blood culture bottles with organisms present in gram stains were prospectively analysed by maldi-tof. three lysis reagents (saponin, sds, and sepsityper lysis bufer) were applied to ... | 2017 | 28100271 |
| rectal carriage of extended-spectrum beta-lactamase and carbapenemase producing gram-negative bacilli in intensive care units in tunisia. | this study was conducted to evaluate the rate of fecal carriage of gram-negative bacilli (gnb) resistant to third-generation cephalosporins (third gc) in patients hospitalized in the intensive care unit (icu) of charles nicolle hospital of tunis and to identify the enzymatic mechanisms involved. from february to april 2014, rectal swabs were collected from all patients (n = 38) at admission and once weekly thereafter to identify acquisition. they were cultured on desoxycholate-lactose-agar plate ... | 2017 | 28099062 |
| emergence of blandm-7-producing enterobacteriaceae in gabon, 2016. | reports of carbapenemase-producing enterobacteriaceae in africa remain rare and assess mostly blaoxa-48-producing isolates from mediterranean countries and south africa. we identified blandm-7-producing enterobacteriaceae in gabon in 2016. the isolates contained blandm-7 incx3 plasmids that were unusual and similar to the one described in a colistin-resistant klebsiella pneumoniae sz04 isolate from china. | 2017 | 28098536 |
| multiple liver abscesses and bacteremia caused by streptococcus constellatus infection: a case report. | the streptococcus milleri group (smg) comprises commensal mucosal bacteria. pyogenic liver abscesses due to hematogenous smg infection are rare but can be observed even in healthy patients. in such cases, physicians should consider the existence of primary lesions that allow penetration of the smg. | 2016 | 28096994 |
| multiple liver abscesses and bacteremia caused by streptococcus constellatus infection: a case report. | the streptococcus milleri group (smg) comprises commensal mucosal bacteria. pyogenic liver abscesses due to hematogenous smg infection are rare but can be observed even in healthy patients. in such cases, physicians should consider the existence of primary lesions that allow penetration of the smg. | 2016 | 28096994 |
| development of an algorithm for phenotypic screening of carbapenemase-producing enterobacteriaceae in the routine laboratory. | carbapenemase-producing enterobacteriaceae (cpe) are difficult to identify among carbapenem non-susceptible enterobacteriaceae (nse). we designed phenotypic strategies giving priority to high sensitivity for screening putative cpe before further testing. | 2017 | 28095794 |
| bacterial plasmid-mediated quinolone resistance genes in aquatic environments in china. | emerging antimicrobial resistance is a major threat to human's health in the 21(st) century. understanding and combating this issue requires a full and unbiased assessment of the current status on the prevalence of antimicrobial resistance genes and their correlation with each other and bacterial groups. in aquatic environments that are known reservoirs for antimicrobial resistance genes, we were able to reach this goal on plasmid-mediated quinolone resistance (pmqr) genes that lead to resistanc ... | 2017 | 28094345 |
| antimicrobial properties of plant essential oils against human pathogens and their mode of action: an updated review. | a wide range of medicinal and aromatic plants (maps) have been explored for their essential oils in the past few decades. essential oils are complex volatile compounds, synthesized naturally in different plant parts during the process of secondary metabolism. essential oils have great potential in the field of biomedicine as they effectively destroy several bacterial, fungal, and viral pathogens. the presence of different types of aldehydes, phenolics, terpenes, and other antimicrobial compounds ... | 2016 | 28090211 |
| in vitro activity of ceftazidime/avibactam against urinary isolates from patients in a phase 3 clinical trial programme for the treatment of complicated urinary tract infections. | to evaluate the in vitro activity of ceftazidime/avibactam relative to comparator agents against gram-negative isolates from a phase 3 clinical trial programme for complicated urinary tract infections (recapture). | 2017 | 28088768 |
| intestinal bacterial colonization in the first 2 weeks of life of nigerian neonates using standard culture methods. | the pattern and timing of development of intestinal microflora in nigerian infants have been scarcely researched. this study was carried out to investigate the bacteria flora in the rectum of healthy neonates in ibadan, nigeria. | 2016 | 28083526 |
| detection of ampc β-lactamase producing bacteria isolated in neonatal sepsis. | the objective of this study was to determine the occurrence and antimicrobial profile of ampc β-lactamase producing bacteria. | 2016 | 28083055 |
| an updated review on the phytochemistry, pharmacology, and clinical trials of salacia oblonga. | salacia oblonga (s. oblonga), a perennial herb, has been used for thousands of years in ayurvedic medicine and is closely associated with prevention, treatment, and cure of various human ailments such as obesity and diabetes. a vast and wide range of chemical compounds such as polyphenols, friedelane-type triterpenes, norfriedelane-type triterpenes, eudesmane-type sesquiterpenes including various glycosides had been isolated from this plant. this review is aimed to survey the literature covering ... | 2016 | 28082793 |
| high-quality genome sequence of human pathogen enterobacter asburiae type strain 1497-78(t). | enterobacter asburiae belongs to the enterobacter cloacae complex (ecc), which comprises six heterogenic species. these bacteria can cause nosocomial infections. moreover, they are well known for antibiotic resistance features based on overproduction of ampc β-lactamases. although ecc have clinical importance, little is known about their virulence-associated properties, and very few strains from the six species have been sequenced. in this study, the type strain of e. asburiae 1497-78(t) (atcc 3 ... | 2017 | 28082144 |
| the influence of antibiotic prophylaxis on bacterial resistance in urinary tract infections in children with spina bifida. | bacterial resistance to antibiotics is an increasingly threatening consequence of antimicrobial exposure for many decades now. in urinary tract infections (utis), antibiotic prophylaxis (ap) increases bacterial resistance. we studied the resistance patterns of positive urinary cultures in spina bifida children on clean intermittent catheterization, both continuing and stopping ap. | 2017 | 28081719 |
| microrna-155 is upregulated in ascites in patients with spontaneous bacterial peritonitis. | mircorna's (mir) have been recognised as important modulators of gene expression and potential biomarkers. however, they have been rarely investigated in bio fluids apart from blood. we investigated the association of mir-125b and mir-155 with complications of cirrhosis. ascites was prospectively collected from patients with cirrhosis undergoing paracentesis at our department. mir's were determined in the supernatant using qpcr and normalized by sv-40. clinical parameters were assessed at parace ... | 2017 | 28074870 |
| proceedings of réanimation 2017, the french intensive care society international congress. | 2017 | 28074416 | |
| proceedings of réanimation 2017, the french intensive care society international congress. | 2017 | 28074415 | |
| antimicrobial activity of ceftazidime-avibactam and comparator agents when tested against bacterial isolates causing infection in cancer patients (2013-2014). | we evaluated the antimicrobial susceptibility of 623 gram-negative organisms causing infection in patients with cancer in 52 united states hospitals (2013-2014) as part of the international network for optimal resistance monitoring (inform) program. isolates were tested for susceptibility by broth microdilution method. β-lactamase encoding genes were evaluated for all escherichia coli and klebsiella spp. with an extended-spectrum β-lactamase (esbl) phenotype by microarray-based assay. esbl-pheno ... | 2017 | 28069328 |
| development of a recombinase polymerase amplification assay for detection of epidemic human noroviruses. | human norovirus is a leading cause of viral gastroenteritis worldwide. rapid detection could facilitate control, however widespread point-of-care testing is infrequently done due to the lack of robust and portable methods. recombinase polymerase amplification (rpa) is a novel isothermal method which rapidly amplifies and detects nucleic acids using a simple device in near real-time. an rt-rpa assay targeting a recent epidemic human norovirus strain (gii.4 new orleans) was developed and evaluated ... | 2017 | 28067278 |
| intestinal enterobacteriaceae that protect nematodes from the effects of benzimidazoles. | the objective of this study was to investigate an interaction between nematodes and gut enterobacteriaceae that use benzimidazoles as a carbon source. by addressing this objective, we identified an anthelmintic resistance-like mechanism for gastrointestinal nematodes. we isolated 30 gut bacteria (family enterobacteriaceae) that subsist on and putatively catabolize benzimidazole-class anthelmintics. c. elegans was protected from the effects of benzimidazoles when co-incubated with these enterobac ... | 2016 | 28066686 |
| shifted focus of bronchoalveolar lavage in patients with suspected thoracic malignancy: an analysis of 224 patients. | bronchoscopies are extensively adopted for diagnosing and staging thoracic malignancies, but studies are missing as how to keep the process streamlined and more efficient. to evaluate current role of bronchoalveolar lavage (bal) for cancer and possible infection diagnosis when practicing comprehensive bronchoscopy for patients suspected with thoracic malignancy, and provide foundation for possible practice modification. | 2016 | 28066604 |
| altered outer membrane transcriptome balance with ampc overexpression in carbapenem-resistant enterobacter cloacae. | the growing incidence of multidrug-resistant (mdr) bacteria is an emerging challenge in modern medicine. the utility of carbapenems, considered "last-line" agents in therapy of infections caused by mdr pathogens, is being diminished by the growing incidence of various resistance mechanisms. enterobacter cloacae have lately begun to emerge as an important pathogen prone to exhibiting multiple drug resistance. we aimed to investigate the molecular basis of carbapenem-resistance in 44 e. cloacae cl ... | 2016 | 28066375 |
| multiple cross displacement amplification combined with gold nanoparticle-based lateral flow biosensor for detection of vibrio parahaemolyticus. | vibrio parahaemolyticus (v. parahaemolyticus) is a marine seafood-borne pathogen causing severe illnesses in humans and aquatic animals. in the present study, multiple cross displacement amplification was combined with a lateral flow biosensor (mcda-lfb) to detect the toxr gene of v. parahaemolyticus in dna extracts from pure cultures and spiked oyster homogenates. amplification was carried out at a constant temperature (62°c) for only 30 min, and amplification products were directly applied to ... | 2016 | 28066368 |
| antibacterial activities of the methanol extract, fractions and compounds from elaeophorbia drupifera (thonn.) stapf. (euphorbiaceae). | elaeophorbia drupifera (thonn.) stapf. (euphorbiaceae) is used in cameroonian folk medicine to treat several ailments including bacterial-related diseases such as skin infections. in this study, the methanol extract from the leaves (edl), fractions (edla-d), sub-fractions edlc1-7 and edlc31-35 as well as isolated compounds were tested for their antimicrobial activities against a panel of gram-negative and gram-positive bacteria including multidrug resistant (mdr) phenotypes. | 2017 | 28061888 |
| the efficacy of noble metal alloy urinary catheters in reducing catheter-associated urinary tract infection. | catheter-associated urinary tract infection (cauti) is the most common device-related healthcare-acquired infection. cauti can be severe and lead to bacteremia, significant morbidity, prolonged hospital stay, and high antibiotic consumption. | 2016 | 28057985 |
| risk factors and characteristics of blood stream infections in patients with newly diagnosed multiple myeloma. | patients with multiple myeloma are generally immune-compromised either due to pronounced depression in primary antibody responses or because of anti-myeloma therapy. infection is a major risk factor for early deaths among these patients. the impact of blood stream infections (bsi) on newly diagnosed myeloma patients has been less studied. we aimed to study the incidence and risk factors of bsi within 3 months after diagnosis of multiple myeloma in a tertiary referral center. | 2017 | 28056867 |
| prevalence of multidrug-resistant organisms in refugee patients, medical tourists and domestic patients admitted to a german university hospital. | patients with contact to healthcare-system in high-prevalence countries (hpc) and refugee patients in hospital settings (ref) have previously been identified to be at risk of carrying multidrug-resistant organisms (mdro). comparative studies addressing the epidemiology of mdro in patients transferred from hospitals abroad (abroad) and ref are lacking but are necessary to introduce refined infection control measures. | 2017 | 28056820 |
| evaluation of aerial microbial pollutants in al-haram al-nabawi during pilgrimage of 2013. | al-madinah al-munawwarah is the second holiest site in islam. the possibility of new emerging microbes is valid due to the increased number of pilgrims. the objectives of the current study were to estimate the numbers of fungi and bacteria inside and outside al-haram al-nabawi and to find whether new bacterial and fungal species have emerged compared to previous studies. air samples were collected twice a day from 12 spots and four directions during the pilgrim year of 2013 for four consecutive ... | 2015 | 28053593 |
| evaluation of aerial microbial pollutants in al-haram al-nabawi during pilgrimage of 2013. | al-madinah al-munawwarah is the second holiest site in islam. the possibility of new emerging microbes is valid due to the increased number of pilgrims. the objectives of the current study were to estimate the numbers of fungi and bacteria inside and outside al-haram al-nabawi and to find whether new bacterial and fungal species have emerged compared to previous studies. air samples were collected twice a day from 12 spots and four directions during the pilgrim year of 2013 for four consecutive ... | 2015 | 28053593 |
| abstracts. | 2017 | 28044356 | |
| the pharmacodynamics of avibactam in combination with ceftaroline or ceftazidime against β-lactamase-producing enterobacteriaceae studied in an in vitro model of infection. | pharmacodynamics of β-lactamase inhibitors are an area of intense interest as new β-lactam/β-lactamase inhibitor combinations enter clinical development and clinical practice. avibactam, a non-β-lactam β-lactamase inhibitor, has been combined with ceftaroline or ceftazidime but these two combinations have not been directly compared. | 2017 | 28039276 |
| the clinical impact of rapid, direct maldi-tof identification of bacteria from positive blood cultures. | faster identification of bacterial isolates from blood cultures can enable earlier clinical intervention for patients with sepsis. we evaluated the clinical impact of direct identification of micro-organisms from positive blood cultures using maldi-tof. | 2016 | 28036369 |
| draft genome sequences of biosafety level 2 opportunistic pathogens isolated from the environmental surfaces of the international space station. | the draft genome sequences of 20 biosafety level 2 (bsl-2) opportunistic pathogens isolated from the environmental surfaces of the international space station (iss) were presented. these genomic sequences will help in understanding the influence of microgravity on the pathogenicity and virulence of these strains when compared with earth strains. | 2016 | 28034853 |
| management of acute hematogenous infection following total knee arthroplasty: a case series of 11 patients. | acute hematogenous infection is a devastating complication that can occur after total knee arthroplasty (tka). the best strategies for management of this infection remain controversial. two-stage revision has been well described as the gold standard for the management of chronic late infections. however, there is a paucity of information presently available on the management and outcomes of patients treated for acute hematogenous infections. the purpose of the present study was to report the out ... | 2016 | 28032700 |
| antibiofilm efficacy of green synthesized graphene oxide-silver nanocomposite using lagerstroemia speciosa floral extract: a comparative study on inhibition of gram-positive and gram-negative biofilms. | biofilm architecture provides bacteria with enhanced antibiotic resistance, thus raising the need to search for alternative therapies that can inhibit the bacterial colonization. in the present study, we synthesized graphene oxide-silver nanocomposite (go-ag) by non-toxic and eco-friendly route using a floral extract of legistromia speciosa (l.) pers. the gas chromatography-mass spectrometry (gc-ms) analysis of plant extract revealed the presence of compounds which can simultaneously act as redu ... | 2017 | 28027944 |
| a mechanism of synergistic effect of streptomycin and cefotaxime on ctx-m-15 type β-lactamase producing strain of e. cloacae: a first report. | a blactx-m-15 gene is one of the most prevalent resistant marker found in member of enterobacteriaceae. it encodes cefotaxime hydrolysing β-lactamase-15 (ctx-m-15) causing resistance against beta lactam antibiotics. since single antibiotic therapy fails to control infection caused by multidrug resistance strain, therefore combination therapy was came into practice as an effective treatment. we have first time explained the mechanism where two antibiotics of different classes work against resista ... | 2016 | 28018328 |
| [epidemiology and risk factors of patients with intra-abdominal postsurgical infection treated with tigecycline: a cohort study]. | to study a cohort of patients with intra-abdominal postsurgical infection treated with tigecycline to analyze its effectiveness and mortality related factors. | 2017 | 28010058 |
| combination therapy with vancomycin-loaded calcium sulfate and vancomycin-loaded pmma in the treatment of chronic osteomyelitis. | chronic post-traumatic and postoperative osteomyelitis is a refractory disease which results in significant morbidity and mortality. the effect of combination therapy with vancomycin-loaded calcium sulfate and vancomycin-loaded polymethyl methacrylate (pmma) was unknown. | 2016 | 28007027 |
| salvage plasmapheresis for post-hepatectomy liver failure. | in the latest decades, an important change has been registered in liver surgery related to the progress of surgical techniques, critical care, and postoperative treatment, allowing a sharp decrease in mortality and morbidity. however, management of post-hepatectomy liver failure (phlf) still remains a challenge and no supportive treatment has been found to be generally effective. the present study is a reappraisal of plasmapheresis as a potential supportive measure in patients with phlf followin ... | 2016 | 28003948 |
| neonatal bacterial conjunctivitis in korea in the 21st century. | to investigate the microbial cause and antibiotic susceptibility of neonatal bacterial conjunctivitis in korean patients in the 21st century. | 2017 | 28002109 |
| purification, characterization and comparison between two new l-asparaginases from bacillus pg03 and bacillus pg04. | l-asparaginase has been used as a chemotherapeutic agent in treatment of lymphoblastic leukemia. in the present investigation, bacillus sp. pg03 and bacillus sp. pg04 were studied. | 2016 | 27999622 |
| development and application of a synthetically-derived lead biosensor construct for use in gram-negative bacteria. | the use of lead in manufacturing has decreased significantly over the last few decades. however, previous widespread use of lead-containing products and their incorrect disposal has resulted in environmental contamination. accumulation of harmful quantities of lead pose a threat to all living organisms, through inhalation, ingestion, or direct contact, resulting in lead poisoning. this study utilized synthetic biology principles to develop plasmid-based whole-cell bacterial biosensors for detect ... | 2016 | 27999352 |
| evaluation of a commercial multiplex pcr assay for detection of pathogen dna in blood from patients with suspected sepsis. | the magicplex sepsis real-time test (mst) is a commercial multiplex pcr that can detect more than 90 different pathogens in blood, with an analysis time of six hours. the aim of the present study was to evaluate this method for the detection of bloodstream infection (bsi). an edta whole blood sample for mst was collected together with blood cultures (bc) from patients with suspected sepsis at the emergency department of a university hospital. among 696 study patients, 322 (46%) patients were pos ... | 2016 | 27997618 |
| longipin: an amyloid antimicrobial peptide from the harvestman acutisoma longipes (arachnida: opiliones) with preferential affinity for anionic vesicles. | in contrast to vertebrate immune systems, invertebrates lack an adaptive response and rely solely on innate immunity in which antimicrobial peptides (amps) play an essential role. most of them are membrane active molecules that are typically unstructured in solution and adopt secondary/tertiary structures upon binding to phospholipid bilayers. this work presents the first characterization of a constitutive amp from the hemolymph of an opiliones order animal: the harvestman acutisoma longipes. th ... | 2016 | 27997568 |
| recurrent episodes of candidemia due to candida glabrata, candida tropicalis and candida albicans with acquired echinocandin resistance. | mixed fungal infection and acquired echinocandin resistance of candida spp. remain infrequent. in this study we have reported the case of a patient hospitalized for tuberculosis who experienced multiple infections due to three common candida species (c. albicans, c. glabrata, c. tropicalis). furthermore, consecutive isolates from blood cultures and heart valve were found resistant to azoles (c. tropicalis) and to echinocandin with either novel (c. tropicalis) or previously described (c. albicans ... | 2016 | 27995055 |
| intravenous colistin use for multidrug-resistant gram-negative infections in pediatric patients. | the emergence of infections due to multidrug-resistant gram-negative bacilli (mdr-gnb) has led to the resurrection of colistin use. the data on colistin use and drug-related adverse effects in children are scarce. | 2016 | 27994915 |
| the most common detected bacteria in sputum of patients with community acquired pneumonia (cap) treated in hospital. | community acquired pneumonia (cap) is the most common infective pulmonary disease. | 2016 | 27994296 |
| corrigendum to "carbapenem susceptibility among escherichia coli, klebsiella pneumoniae, and enterobacter cloacae isolates obtained from patients in intensive care units in taiwan in 2005, 2007, and 2009" [diagn microbiol infect dis 2015;81(4):290-295]. | 2017 | 27993423 |