Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| clinical sensitivity and specificity of a real-time pcr assay for campylobacter fetus subsp venerealis in preputial samples from bulls. | to determine clinical sensitivity and specificity of a quantitative real-time pcr (qrt-pcr) assay for campylobacter fetus subsp venerealis (cfv) in preputial samples of bulls. | 2014 | 25157889 |
| novel microbiological and spatial statistical methods to improve strength of epidemiological evidence in a community-wide waterborne outbreak. | failures in the drinking water distribution system cause gastrointestinal outbreaks with multiple pathogens. a water distribution pipe breakage caused a community-wide waterborne outbreak in vuorela, finland, july 2012. we investigated this outbreak with advanced epidemiological and microbiological methods. a total of 473/2931 inhabitants (16%) responded to a web-based questionnaire. water and patient samples were subjected to analysis of multiple microbial targets, molecular typing and microbia ... | 2014 | 25147923 |
| complete genome sequence of campylobacter iguaniorum strain 1485et, isolated from a bearded dragon (pogona vitticeps). | campylobacter iguaniorum has been isolated from reptiles. this campylobacter species is genetically related to campylobacter fetus and campylobacter hyointestinalis. here we present the first whole-genome sequence for this species. | 2014 | 25146144 |
| a quantitative prioritisation of human and domestic animal pathogens in europe. | disease or pathogen risk prioritisations aid understanding of infectious agent impact within surveillance or mitigation and biosecurity work, but take significant development. previous work has shown the h-(hirsch-)index as an alternative proxy. we present a weighted risk analysis describing infectious pathogen impact for human health (human pathogens) and well-being (domestic animal pathogens) using an objective, evidence-based, repeatable approach; the h-index. this study established the highe ... | 2014 | 25136810 |
| neurological disorders and inflammatory bowel diseases. | extraintestinal manifestations occur in about one-third of patients living with inflammatory bowel disease (ibd) and may precede the onset of gastrointestinal symptoms by many years. neurologic disorders associated with ibd are not frequent, being reported in 3% of patients, but they often represent an important cause of morbidity and a relevant diagnostic issue. in addition, the increasing use of immunosuppressant and biological therapies for ibd may also play a pivotal role in the development ... | 2014 | 25083051 |
| campylobacter fetus bacteremia in an immunocompetent traveler. | campylobacter fetus bacteremia is a rare human infection that occurs almost exclusively in the setting of advanced age, immunosuppression, human immunodeficiency virus infection, alcoholism, or recent gastrointestinal surgery. this report of c. fetus bacteremia in a 39-year-old immunocompetent traveler who ate raw beef identifies c. fetus as a potential emerging pathogen in normal hosts. | 2014 | 25071002 |
| ultrastructure and complex polar architecture of the human pathogen campylobacter jejuni. | campylobacter jejuni is one of the most successful food-borne human pathogens. here we use electron cryotomography to explore the ultrastructure of c. jejuni cells in logarithmically growing cultures. this provides the first look at this pathogen in a near-native state at macromolecular resolution (~5 nm). we find a surprisingly complex polar architecture that includes ribosome exclusion zones, polyphosphate storage granules, extensive collar-shaped chemoreceptor arrays, and elaborate flagellar ... | 2014 | 25065852 |
| detection, identification and quantification of campylobacter jejuni, coli and lari in food matrices all at once using multiplex qpcr. | thermotolerant campylobacter jejuni, coli and lari are recognized as leading food-borne pathogens causing an acute bacterial enteritis worldwide. due to narrow spectrum of their biochemical activity, it is very complicated to distinguish between individual species. for reliable risk assessment, proper incidence evaluation or swift sample analysis regarding individual species, a demand for simple and rapid method for their distinguishing is reasonable. in this study, we evaluated a reliable and s ... | 2014 | 25057300 |
| microbial typing by matrix-assisted laser desorption ionization-time of flight mass spectrometry: do we need guidance for data interpretation? | the integration of matrix-assisted laser desorption ionization-time of flight mass spectrometry (maldi-tof ms) in clinical microbiology has revolutionized species identification of bacteria, yeasts, and molds. however, beyond straightforward identification, the method has also been suggested to have the potential for subspecies-level or even type-level epidemiological analyses. this minireview explores maldi-tof ms-based typing, which has already been performed on many clinically relevant specie ... | 2014 | 25056329 |
| microbial typing by matrix-assisted laser desorption ionization-time of flight mass spectrometry: do we need guidance for data interpretation? | the integration of matrix-assisted laser desorption ionization-time of flight mass spectrometry (maldi-tof ms) in clinical microbiology has revolutionized species identification of bacteria, yeasts, and molds. however, beyond straightforward identification, the method has also been suggested to have the potential for subspecies-level or even type-level epidemiological analyses. this minireview explores maldi-tof ms-based typing, which has already been performed on many clinically relevant specie ... | 2014 | 25056329 |
| mycotic abdominal aortic aneurysm caused by campylobacter fetus: a case report and literature review. | campylobacter spp. usually cause gastrointestinal infections, but among them, campylobacter fetus is a well-known organism causing mycotic abdominal aortic aneurysm (maaa), which requires proper surgical intervention and antibiotic therapy. we report a 65-year-old man who was successfully treated by an in situ operation using a rifampicin (rfp)-bonded j-graft for c. fetus-induced maaa. we performed a review of the english literature on maaa caused by c. fetus and summarized the results of the ca ... | 2014 | 25017776 |
| occurrence, diversity, and host association of intestinal campylobacter, arcobacter, and helicobacter in reptiles. | campylobacter, arcobacter, and helicobacter species have been isolated from many vertebrate hosts, including birds, mammals, and reptiles. multiple studies have focused on the prevalence of these epsilonproteobacteria genera in avian and mammalian species. however, little focus has been given to the presence within reptiles, and their potential zoonotic and pathogenic roles. in this study, occurrence, diversity, and host association of intestinal epsilonproteobacteria were determined for a large ... | 2014 | 24988130 |
| association between proton pump inhibitor use and spontaneous bacterial peritonitis in cirrhotic patients with ascites. | there are data suggesting a link between proton pump inhibitor (ppi) use and the development of spontaneous bacterial peritonitis (sbp) in cirrhotic patients with ascites; however, these data are controversial. | 2014 | 24945188 |
| conserved evolutionary units in the heme-copper oxidase superfamily revealed by novel homologous protein families. | the heme-copper oxidase (hco) superfamily includes hcos in aerobic respiratory chains and nitric oxide reductases (nors) in the denitrification pathway. the hco/nor catalytic subunit has a core structure consisting of 12 transmembrane helices (tmhs) arranged in three-fold rotational pseudosymmetry, with six conserved histidines for heme and metal binding. using sensitive sequence similarity searches, we detected a number of novel hco/nor homologs and named them hco homology (hcoh) proteins. seve ... | 2014 | 24931479 |
| mycotic popliteal aneurysm rupture secondary to campylobacter fetus. | mycotic aneurysms of the popliteal artery are uncommon. popliteal aneurysms rarely rupture. the authors present the second reported case of popliteal artery rupture as a result of campylobacter fetus infection. this report confirms the arterial destructive potential of c. fetus infection in a peripheral artery. | 2015 | 24930978 |
| campylobacter fetus subsp. testudinum subsp. nov., isolated from humans and reptiles. | a polyphasic study was undertaken to determine the taxonomic position of 13 campylobacter fetus-like strains from humans (n = 8) and reptiles (n = 5). the results of matrix-assisted laser desorption ionization time-of-flight (maldi-tof) ms and genomic data from sap analysis, 16s rrna gene and hsp60 sequence comparison, pulsed-field gel electrophoresis, amplified fragment length polymorphism analysis, dna-dna hybridization and whole genome sequencing demonstrated that these strains are closely re ... | 2014 | 24899653 |
| campylobacter fetus bacteremia with purulent pleurisy in a young adult with primary hypogammaglobulinemia. | a 24-year-old man presented with fever and pleural effusion predominantly containing lymphocytes. cultures of the pleural effusion and blood revealed campylobacter fetus, and laboratory studies showed a low serum level of immunoglobulin. the patient was diagnosed with c. fetus pleuritis, bacteremia and primary hypogammaglobulinemia, and subsequent treatment with meropenem and immunoglobulin improved his condition. although the underlying cause of the primary hypogammaglobulinemia remains unclear ... | 2014 | 24881753 |
| annotation of protein domains reveals remarkable conservation in the functional make up of proteomes across superkingdoms. | the functional repertoire of a cell is largely embodied in its proteome, the collection of proteins encoded in the genome of an organism. the molecular functions of proteins are the direct consequence of their structure and structure can be inferred from sequence using hidden markov models of structural recognition. here we analyze the functional annotation of protein domain structures in almost a thousand sequenced genomes, exploring the functional and structural diversity of proteomes. we find ... | 2011 | 24710297 |
| a multiplex pcr/ldr assay for simultaneous detection and identification of the niaid category b bacterial food and water-borne pathogens. | enteric pathogens that cause gastroenteritis remain a major global health concern. the goal of this study was to develop a multiplex pcr/ligation detection reaction (ldr) assay for the detection of all niaid category b bacterial food and water-borne pathogens directly from stool specimens. to validate the pcr/ldr assay, clinical isolates of campylobacter spp., vibrio spp., shigella spp., salmonella spp., listeria monocytogenes, yersinia enterocolitica, and diarrheagenic escherichia coli were tes ... | 2014 | 24709368 |
| survey of infectious etiologies of bovine abortion during mid- to late gestation in dairy herds. | bovine abortion of unknown infectious etiology still remains a major economic problem. thus, we investigated whether brucella spp., listeria monocytogenes, salmonella spp., campylobacter spp. and coxiella burnetii are associated with abortion and/or stillbirth in tunisian dairy cattle. using a pan-chlamydiales pcr, we also investigated the role of chlamydiaceae, waddlia chondrophila, parachlamydia acanthamoebae and other members of the chlamydiales order in this setting. veterinary samples taken ... | 2014 | 24662769 |
| genetic diversity and antimicrobial susceptibility of campylobacter jejuni isolates associated with sheep abortion in the united states and great britain. | campylobacter infection is a leading cause of ovine abortion worldwide. historically, genetically diverse campylobacter fetus and campylobacter jejuni strains have been implicated in such infections, but since 2003 a highly pathogenic, tetracycline-resistant c. jejuni clone (named sa) has become the predominant cause of sheep abortions in the united states. whether clone sa was present in earlier u.s. abortion isolates (before 2000) and is associated with sheep abortions outside the united state ... | 2014 | 24648552 |
| subcutaneous immunization with inactivated bacterial components and purified protein of escherichia coli, fusobacterium necrophorum and trueperella pyogenes prevents puerperal metritis in holstein dairy cows. | in this study we evaluate the efficacy of five vaccine formulations containing different combinations of proteins (fimh; leukotoxin, lkt; and pyolysin, plo) and/or inactivated whole cells (escherichia coli, fusobacterium necrophorum, and trueperella pyogenes) in preventing postpartum uterine diseases. inactivated whole cells were produced using two genetically distinct strains of each bacterial species (e. coli, f. necrophorum, and t. pyogenes). fimh and plo subunits were produced using recombin ... | 2014 | 24638139 |
| campylobacter fetus infections. | campylobacter fetus infections usually occur in immunodepressed patients or patients presenting with diabetes mellitus or cancer. they rarely cause diarrhea but frequently cause bacteremia or vascular diseases. the therapeutic management is not well codified and fluoroquinolone resistance is continuously increasing. | 2014 | 24637053 |
| campylobacter bacteremia: a rare and under-reported event? | bacteria belonging to the species campylobacter are the most common cause of bacterial diarrhoea in humans. the clinical phenotype associated with campylobacter infections ranges from asymptomatic conditions to severe colitis and bacteremia. in susceptible patients, campylobacter infections are associated with significant morbidity and mortality, with both host factors and bacterial factors being involved in the pathogenesis of bacteremia. in the host, age, gender and immune-compromising conditi ... | 2012 | 24611124 |
| so close and yet so far - molecular microbiology of campylobacter fetus subspecies. | campylobacter fetus comprises two subspecies, c. fetus subsp. fetus and c. fetus subsp. venerealis, which are considered emerging pathogens in humans and animals. comparisons at the genome level have revealed modest subspecies-specific variation; nevertheless, these two subspecies show distinct host and niche preferences. c. fetus subsp. fetus is a commensal and pathogen of domesticated animals that can be transmitted to humans via contaminated food. the clinical features of human infection can ... | 2012 | 24611123 |
| putative mechanisms and biological role of coccoid form formation in campylobacter jejuni. | in certain conditions campylobacter jejuni cells are capable of changing their cell shape from a typically spiral to a coccoid form (cf). by similarity to other bacteria, the latter was initially considered to be a viable but non-culturable form capable of survival in unfavourable conditions. however, subsequent studies with c. jejuni and closely related bacteria helicobacter pylori suggested that cf represents a non-viable, degenerative form. until now, the issue on whether the cf of c. jejuni ... | 2012 | 24611120 |
| the role of crispr-cas systems in virulence of pathogenic bacteria. | clustered regularly interspaced short palindromic repeats (crispr) and crispr-associated (cas) genes are present in many bacterial and archaeal genomes. since the discovery of the typical crispr loci in the 1980s, well before their physiological role was revealed, their variable sequences have been used as a complementary typing tool in diagnostic, epidemiologic, and evolutionary analyses of prokaryotic strains. the discovery that crispr spacers are often identical to sequence fragments of mobil ... | 2014 | 24600041 |
| tweak promotes peritoneal inflammation. | peritoneal dialysis (pd) is complicated by peritonitis episodes that cause loss of mesothelium and eventually sclerosing peritonitis. an improved understanding of the molecular contributors to peritoneal injury and defense may increase the therapeutic armamentarium to optimize peritoneal defenses while minimizing peritoneal injury. there is no information on the expression and function of the cytokine tweak and its receptor fn14 during peritoneal injury. fn14 expression and soluble tweak levels ... | 2014 | 24599047 |
| a case of bacteremia caused by campylobacter fetus: an unusual presentation in an infant. | bacteremia due to campylobacter spp. is rarely reported, and campylobacter fetus is the species most commonly exhibiting vascular tropism, as occurred in this case report describing the diagnosis of c. fetus bacteremia in an infant presenting with respiratory tract infection. a 5-month-old baby, with undiagnosed failure to thrive, presented to the acute care service with a high fever and respiratory symptoms of 2 days duration. the initial clinical and laboratory diagnosis suggested bacteremia, ... | 2014 | 24596467 |
| pregnancy rates of beef cattle are not affected by campylobacter fetus subsp. venerealis real-time pcr-positive breeding sires in new zealand. | campylobacter fetus subspecies venerealis (c. fetus venerealis) is the causal agent of bovine genital campylobacteriosis, a venereal disease that is asymptomatic in bulls but responsible for reproductive wastage in female cattle. in new zealand, a commercial real-time pcr assay was introduced in 2007 to identify the dna of this pathogen in preputial scrapings; however, concerns were raised about the specificity of the test following anecdotal reports of a high number of test-positive bulls with ... | 2014 | 24580097 |
| infective endocarditis in northeastern thailand. | despite rigorous diagnostic testing, the cause of infective endocarditis was identified for just 60 (45.5%) of 132 patients admitted to hospitals in khon kaen, thailand, during january 2010-july 2012. most pathogens identified were viridans streptococci and zoonotic bacteria species, as found in other resource-limited countries where underlying rheumatic heart disease is common. | 2014 | 24572588 |
| campylobacter fetus infections in humans: exposure and disease. | campylobacter fetus can cause intestinal illness and, occasionally, severe systemic infections. infections mainly affect persons at higher risk, including elderly and immunocompromised individuals and those with occupational exposure to infected animals. outbreaks are infrequent but have provided insight into sources. source attribution of sporadic cases through case-control interviews has not been reported. the reservoirs for c. fetus are mainly cattle and sheep. products from these animals are ... | 2014 | 24550377 |
| vibrio fetus infection in sheep. | 1961 | 24546570 | |
| first closed genome sequence of campylobacter fetus subsp. venerealis bv. intermedius. | campylobacter fetus subsp. venerealis bv. intermedius is a variant of c. fetus subsp. venerealis, the causative agent of bovine genital campylobacteriosis, a venereal disease associated with abortion and infertility in cattle. we report the first closed whole-genome sequence of this biovar. | 2014 | 24503995 |
| the dynamic nature of genomes across the tree of life. | genomes are dynamic in lineages across the tree of life. among bacteria and archaea, for example, dna content varies throughout life cycles, and nonbinary cell division in diverse lineages indicates the need for coordination of the inheritance of genomes. these observations contrast with the textbook view that bacterial and archaeal genomes are monoploid (i.e., single copied) and fixed both within species and throughout an individual's lifetime. here, we synthesize information on three aspects o ... | 2014 | 24500971 |
| biological roles of the o-methyl phosphoramidate capsule modification in campylobacter jejuni. | campylobacter jejuni is a major cause of bacterial gastroenteritis worldwide, and the capsular polysaccharide (cps) of this organism is required for persistence and disease. c. jejuni produces over 47 different capsular structures, including a unique o-methyl phosphoramidate (meopn) modification present on most c. jejuni isolates. although the meopn structure is rare in nature it has structural similarity to some synthetic pesticides. in this study, we have demonstrated, by whole genome comparis ... | 2014 | 24498018 |
| s-layers: principles and applications. | monomolecular arrays of protein or glycoprotein subunits forming surface layers (s-layers) are one of the most commonly observed prokaryotic cell envelope components. s-layers are generally the most abundantly expressed proteins, have been observed in species of nearly every taxonomical group of walled bacteria, and represent an almost universal feature of archaeal envelopes. the isoporous lattices completely covering the cell surface provide organisms with various selection advantages including ... | 2014 | 24483139 |
| epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via toll-like receptors tlr2, tlr1, and tlr6. | bacteria often infect the endometrium of cattle to cause endometritis, uterine disease, and infertility. lipopeptides are commonly found among bacteria and are detected by the toll-like receptor (tlr) cell surface receptor tlr2 on immune cells. heterodimers of tlr2 with tlr1 or tlr6 activate mapk and nuclear factor-κb intracellular signaling pathways to stimulate inflammatory responses. in the endometrium, epithelial and stromal cells are the first to encounter invading bacteria, so the present ... | 2014 | 24437488 |
| identification and characterization of an invasion antigen b gene from the oral pathogen campylobacter rectus. | the oral bacterium, campylobacter rectus, is an etiological agent of periodontitis. the virulence genes of c. rectus are largely unknown. the aim of this study was to query c. rectus for the presence of an invasion antigen b (ciab) gene, which is needed for cell invasion by the related species campylobacter jejuni. pcr and pcr-walking identified a ciab from c. rectus. in silico analyses of c. rectus 314 ciab (cr-ciab) revealed an orf of 1,830 base pairs. the cr-ciab protein shared significant se ... | 2014 | 24426164 |
| identification and characterization of an invasion antigen b gene from the oral pathogen campylobacter rectus. | the oral bacterium, campylobacter rectus, is an etiological agent of periodontitis. the virulence genes of c. rectus are largely unknown. the aim of this study was to query c. rectus for the presence of an invasion antigen b (ciab) gene, which is needed for cell invasion by the related species campylobacter jejuni. pcr and pcr-walking identified a ciab from c. rectus. in silico analyses of c. rectus 314 ciab (cr-ciab) revealed an orf of 1,830 base pairs. the cr-ciab protein shared significant se ... | 2014 | 24426164 |
| infected pseudoaneurysm of the superficial femoral artery in a patient with salmonella enteritidis bacteremia. | mycotic aneurysms, defined as irreversible dilation of an artery due to destruction of the vessel wall by infection, are rare but are associated with a high risk of rupture if not treated promptly. the case of a healthy 52-year-old smoker who presented with pyrexia, rigors, night sweats and severe right leg pain with swelling is presented. he was diagnosed with a superficial femoral artery mycotic aneurysm, with salmonella enteritidis as the causative agent. he was treated with high-dose antibio ... | 2013 | 24421797 |
| comparative genome analysis of campylobacter fetus subspecies revealed horizontally acquired genetic elements important for virulence and niche specificity. | campylobacter fetus are important animal and human pathogens and the two major subspecies differ strikingly in pathogenicity. c. fetus subsp. venerealis is highly niche-adapted, mainly infecting the genital tract of cattle. c. fetus subsp. fetus has a wider host-range, colonizing the genital- and intestinal-tract of animals and humans. we report the complete genomic sequence of c. fetus subsp. venerealis 84-112 and comparisons to the genome of c. fetus subsp. fetus 82-40. functional analysis of ... | 2014 | 24416416 |
| molecular identification of clinical "difficult-to-identify" microbes from sequencing 16s ribosomal dna and internal transcribed spacer 2. | clinical microbiology laboratories have to accurately identify clinical microbes. however, some isolates are difficult to identify by the automated biochemical text platforms, which are called "difficult-to-identify" microbes in this study. therefore, the ability of 16s ribosomal dna (16s rdna) and internal transcribed spacer 2 (its2) sequencing to identify these "difficult-to-identify" bacteria and fungi was assessed in this study. | 2014 | 24383440 |
| identification of a broad family of lipid a late acyltransferases with non-canonical substrate specificity. | most gram-negative organisms produce lipopolysaccharide (lps), a complex macromolecule anchored to the bacterial membrane by the lipid a moiety. lipid a is synthesized via the raetz pathway, a conserved nine-step enzymatic process first characterized in escherichia coli. the epsilonproteobacterium helicobacter pylori uses the raetz pathway to synthesize lipid a; however, only eight of nine enzymes in the pathway have been identified in this organism. here, we identify the missing acyltransferase ... | 2014 | 24372821 |
| humans and cattle: a review of bovine zoonoses. | infectious disease prevention and control has been among the top public health objectives during the last century. however, controlling disease due to pathogens that move between animals and humans has been challenging. such zoonotic pathogens have been responsible for the majority of new human disease threats and a number of recent international epidemics. currently, our surveillance systems often lack the ability to monitor the human-animal interface for emergent pathogens. identifying and ult ... | 2014 | 24341911 |
| complete genome sequence of campylobacter fetus subsp. testudinum strain 03-427t. | campylobacter fetus subsp. testudinum has been isolated from reptiles and humans. this campylobacter subspecies is genetically distinct from other c. fetus subspecies. here, we present the first whole-genome sequence for this c. fetus subspecies. | 2013 | 24336365 |
| characterization of a campylobacter fetus-like strain isolated from the faeces of a sick leopard tortoise (stigmochelys pardalis) using matrix-assisted laser desorption/ionization time of flight as an alternative to bacterial 16s rdna phylogeny. | this article describes the isolation and characterization of a campylobacter-like isolate originating from the faeces of a sick leopard tortoise. molecular as well as matrix-assisted laser desorption/ionization time-of-flight (maldi-tof) characterization suggests that it could correspond to a new campylobacter species. | 2014 | 24313345 |
| enteric pathogens and reactive arthritis: a systematic review of campylobacter, salmonella and shigella-associated reactive arthritis. | reactive arthritis (rea) is a spondyloarthropathic disorder characterized by inflammation of the joints and tissues occurring after gastrointestinal or genitourinary infections. diagnostic criteria for rea do not exist and, therefore, it is subject to clinical opinion resulting in cases with a wide range of symptoms and definitions. using standardized diagnostic criteria, we conducted a systematic literature review to establish the global incidence of rea for each of the three most commonly-asso ... | 2013 | 24288942 |
| bacterial cell-envelope glycoconjugates. | prokaryotic glycosylation fulfills an important role in maintaining and protecting the structural integrity and function of the bacterial cell wall, as well as serving as a flexible adaption mechanism to evade environmental and host-induced pressure. the scope of bacterial and archaeal protein glycosylation has considerably expanded over the past decade(s), with numerous examples covering the glycosylation of flagella, pili, glycosylated enzymes, as well as surface-layer proteins. this article a ... | 2013 | 24274370 |
| updates on the web-based violin vaccine database and analysis system. | the integrative vaccine investigation and online information network (violin) vaccine research database and analysis system (http://www.violinet.org) curates, stores, analyses and integrates various vaccine-associated research data. since its first publication in nar in 2008, significant updates have been made. starting from 211 vaccines annotated at the end of 2007, violin now includes over 3240 vaccines for 192 infectious diseases and eight noninfectious diseases (e.g. cancers and allergies). ... | 2013 | 24259431 |
| updates on the web-based violin vaccine database and analysis system. | the integrative vaccine investigation and online information network (violin) vaccine research database and analysis system (http://www.violinet.org) curates, stores, analyses and integrates various vaccine-associated research data. since its first publication in nar in 2008, significant updates have been made. starting from 211 vaccines annotated at the end of 2007, violin now includes over 3240 vaccines for 192 infectious diseases and eight noninfectious diseases (e.g. cancers and allergies). ... | 2013 | 24259431 |
| the gut microbiotassay: a high-throughput qpcr approach combinable with next generation sequencing to study gut microbial diversity. | the intestinal microbiota is a complex and diverse ecosystem that plays a significant role in maintaining the health and well-being of the mammalian host. during the last decade focus has increased on the importance of intestinal bacteria. several molecular methods can be applied to describe the composition of the microbiota. this study used a new approach, the gut microbiotassay: an assembly of 24 primer sets targeting the main phyla and taxonomically related subgroups of the intestinal microbi ... | 2013 | 24225361 |
| the role of environmental reservoirs in human campylobacteriosis. | campylobacteriosis is infection caused by the bacteria campylobacter spp. and is considered a major public health concern. campylobacter spp. have been identified as one of the most common causative agents of bacterial gastroenteritis. they are typically considered a foodborne pathogen and have been shown to colonise the intestinal mucosa of all food-producing animals. much emphasis has been placed on controlling the foodborne pathway of exposure, particularly within the poultry industry, howeve ... | 2013 | 24217177 |
| comparison of characteristics of patients infected by campylobacter jejuni, campylobacter coli, and campylobacter fetus. | a large database of campylobacter isolates precisely identified at the species level was used to compare patients' characteristics. in a multivariate analysis, campylobacter coli was found more often in older patients and in patients having traveled abroad and less often in summertime than campylobacter jejuni. campylobacter fetus infection occurred in much older patients and in hospitalized patients with a systemic disease. | 2014 | 24197884 |
| management strategies in the treatment of neonatal and pediatric gastroenteritis. | acute gastroenteritis, characterized by the onset of diarrhea with or without vomiting, continues to be a major cause of morbidity and mortality in children in mostly resource-constrained nations. although generally a mild and self-limiting disease, gastroenteritis is one of the most common causes of hospitalization and is associated with a substantial disease burden. worldwide, up to 40% of children aged less than 5 years with diarrhea are hospitalized with rotavirus. also, some microorganisms ... | 2013 | 24194646 |
| reduction of the abortion rate due to toxoplasma in 3 goat herds following administration of sulfadimidine. | the efficacy of sulfadimidine (4 doses of 33 mg/kg body weight, im, q48h) against toxoplasma abortion was assessed in 3 dairy goat herds suffering from toxoplasma abortions during the 4th month of gestation. this protocol was very effective for the control of toxoplasma abortions (p < 0.01). | 2013 | 24179245 |
| a perspective on the impact of reproductive technologies on food production in africa. | africa for the largest part is still regarded as part of the developing world and has a history of political instability, natural disasters, floods and droughts that all had an effect on the development of livestock production systems and the potential application of biotechnologies. it is expected that the human population in sub saharan africa will experience a growth of 1.2 % per year over the next 30 years. there is therefore pressure to increase sustainable productivity of livestock. reprod ... | 2014 | 24170361 |
| a new addition to the cell plan of anammox bacteria: "candidatus kuenenia stuttgartiensis" has a protein surface layer as the outermost layer of the cell. | anammox bacteria perform anaerobic ammonium oxidation (anammox) and have a unique compartmentalized cell consisting of three membrane-bound compartments (from inside outwards): the anammoxosome, riboplasm, and paryphoplasm. the cell envelope of anammox bacteria has been proposed to deviate from typical bacterial cell envelopes by lacking both peptidoglycan and a typical outer membrane. however, the composition of the anammox cell envelope is presently unknown. here, we investigated the outermost ... | 2014 | 24142254 |
| [campylobacter fetus bacteremia complicating a dysenteric syndrome in a young epileptic]. | campylobacter fetus bacteremia is rare and occurs mainly in elderly and immunosuppressed patients. we report an original observation of c. fetus bacteremia complicating acute mucoid diarrhea in a young epileptic with no known risk factors. our observation suggests that antiepileptic treatment could increase the risk of blood-borne of c. fetus infection. | 2013 | 24113445 |
| lipooligosaccharide locus class of campylobacter jejuni: sialylation is not needed for invasive infection. | campylobacter jejuni is a highly diverse enteropathogen that is commonly detected worldwide. it can sometimes cause bacteraemia, but the bacterial characteristics facilitating bloodstream infection are not known. a total of 73 c. jejuni isolates, consecutively collected from blood-borne infections during a 10-year period all over finland and for which detailed clinical information of the patients were available, were included. we screened the isolates by pcr for the lipooligosaccharide (los) loc ... | 2014 | 24102802 |
| lipooligosaccharide locus class of campylobacter jejuni: sialylation is not needed for invasive infection. | campylobacter jejuni is a highly diverse enteropathogen that is commonly detected worldwide. it can sometimes cause bacteraemia, but the bacterial characteristics facilitating bloodstream infection are not known. a total of 73 c. jejuni isolates, consecutively collected from blood-borne infections during a 10-year period all over finland and for which detailed clinical information of the patients were available, were included. we screened the isolates by pcr for the lipooligosaccharide (los) loc ... | 2014 | 24102802 |
| [mycotic aneurysm of the abdominal aorta caused by campylobacter fetus]. | 2015 | 24094929 | |
| application of a new diagnostic approach to a bovine genital campylobacteriosis outbreak in a saskatchewan beef herd. | a new real-time quantitative polymerase chain reaction (qpcr) test was used to diagnose campylobacter fetus subsp. venerealis infection associated with dramatic reproductive losses in a commercial cow-calf herd. the results were verified with repeated culture, phenotypic characterization of the organism and dna sequencing. this case demonstrates the need for a practical field test for c. fetus subsp. venerealis and the importance of considering this organism as a potential cause of pregnancy fai ... | 2013 | 24082165 |
| temporal and farm-management-associated variation in faecal-pat prevalence of campylobacter fetus in sheep and cattle. | the faecal-pat prevalence (as estimated by culture) of campylobacter fetus from cattle and sheep on 19 farms in rural lancashire was investigated using standard campylobacter culture techniques and pcr during a 2-year longitudinal study. c. fetus was isolated from 9·48% [95% confidence interval (ci) 8·48-10·48] of cattle faecal pats and 7·29% (95% ci 6·21-9·62) of sheep faecal pats. there was evidence of significant differences in shedding prevalence between geographical regions; cows in geograp ... | 2014 | 24067441 |
| human infections with new subspecies of campylobacter fetus. | campylobacter fetus subsp. testudinum subsp. nov. is a newly proposed subspecies of c. fetus with markers of reptile origin. we summarize epidemiologic information for 9 humans infected with this bacterium. all cases were in men, most of whom were of asian origin. infection might have been related to exposure to asian foods or reptiles. | 2013 | 24050521 |
| conferring the ability to utilize inorganic polyphosphate on atp-specific nad kinase. | nad kinase (nadk) is a crucial enzyme for production of nadp⁺. atp-specific nadk prefers atp to inorganic polyphosphate [poly(p)] as a phosphoryl donor, whereas poly(p)/atp-nadk utilizes both atp and poly(p), and is employed in industrial mass production of nadp⁺. poly(p)/atp-nadks are distributed throughout gram-positive bacteria and archaea, whereas atp-specific nadks are found in gram-negative α- and γ-proteobacteria and eukaryotes. in this study, we succeeded in conferring the ability to uti ... | 2013 | 24022322 |
| identification of extracellular surface-layer associated proteins in lactobacillus acidophilus ncfm. | bacterial surface (s-) layers are crystalline arrays of self-assembling, proteinaceous subunits called s-layer proteins (slps), with molecular masses ranging from 40 to 200 kda. the s-layer-forming bacterium lactobacillus acidophilus ncfm expresses three major slps: slpa (46 kda), slpb (47 kda) and slpx (51 kda). slpa has a demonstrated role in adhesion to caco-2 intestinal epithelial cells in vitro, and has been shown to modulate dendritic cell (dc) and t-cell functionalities with murine dcs. i ... | 2013 | 24002751 |
| comparative genomics of campylobacter concisus isolates reveals genetic diversity and provides insights into disease association. | in spite of its association with gastroenteritis and inflammatory bowel diseases, the isolation of campylobacter concisus from both diseased and healthy individuals has led to controversy regarding its role as an intestinal pathogen. one proposed reason for this is the presence of high genetic diversity among the genomes of c. concisus strains. | 2013 | 23984967 |
| deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes. | proteins of unknown function belonging to cog1816 and cog0402 were characterized. sav2595 from steptomyces avermitilis ma-4680, acel0264 from acidothermus cellulolyticus 11b, nis0429 from nitratiruptor sp. sb155-2 and dr0824 from deinococcus radiodurans r1 were cloned, purified, and their substrate profiles determined. these enzymes were previously incorrectly annotated as adenosine deaminases or chlorohydrolases. it was shown here that these enzymes actually deaminate 6-aminodeoxyfutalosine. th ... | 2013 | 23972005 |
| changes in rumen bacterial community composition in steers in response to dietary nitrate. | the effect of dietary nitrate supplementation on rumen bacterial community composition was examined in beef steers fed either a nitrate-n diet or urea-n diet. an automated method of ribosomal intergenic spacer analysis was applied to solid and liquid fractions of ruminal contents to allow comparison of bacterial communities. supplemental n source affected relative population size of four amplicon lengths (als) in the liquid fraction and three als in the solid fraction. five als were more prevale ... | 2013 | 23955503 |
| comprehensive genomic characterization of campylobacter genus reveals some underlying mechanisms for its genomic diversification. | campylobacter species.are phenotypically diverse in many aspects including host habitats and pathogenicities, which demands comprehensive characterization of the entire campylobacter genus to study their underlying genetic diversification. up to now, 34 campylobacter strains have been sequenced and published in public databases, providing good opportunity to systemically analyze their genomic diversities. in this study, we first conducted genomic characterization, which includes genome-wide alig ... | 2013 | 23940551 |
| chronic subdural hematoma infected by campylobacter fetus. | 2013 | 23930907 | |
| prevalence of bovine genital campylobacteriosis and trichomonosis of bulls in northern nigeria. | a survey was conducted to determine the prevalence of campylobacteriosis and trichomonosis, and their concurrence with brucellosis, in cattle in three states of northern nigeria. | 2013 | 23927676 |
| complete genome sequence of campylobacter fetus subsp. venerealis biovar intermedius, isolated from the prepuce of a bull. | campylobacter fetus subsp. venerealis is the causative agent of bovine genital campylobacteriosis, a sexually transmitted disease distributed worldwide. campylobacter fetus subsp. venerealis biovar intermedius strains differ in their biochemical behavior and are prevalent in some countries. we report the first genome sequence for this biovar, isolated from bull prepuce. | 2013 | 23908278 |
| [campylobacter fetus endocarditis: a case report]. | campylobacter are known to be a cause of enteritidic infections but campylobacter fetus is more often a cause of systemic infections, mainly in fragilized patients. we report a c. fetus endocarditis. the prognosis seemstobe improved by a prolonged betalactam antibiotic treatment. | 2013 | 23906576 |
| isolation rates of campylobacter fetus subsp venerealis from bovine preputial samples via passive filtration on nonselective medium versus selective medium, with and without transport medium. | to compare the recovery rates of campylobacter fetus subsp venerealis (cfv) from preputial scrapings of infected bulls with passive filtration on selective medium versus nonselective medium, with and without transport medium. | 2013 | 23879843 |
| accurate identification of fastidious gram-negative rods: integration of both conventional phenotypic methods and 16s rrna gene analysis. | accurate identification of fastidious gram-negative rods (gnr) by conventional phenotypic characteristics is a challenge for diagnostic microbiology. the aim of this study was to evaluate the use of molecular methods, e.g., 16s rrna gene sequence analysis for identification of fastidious gnr in the clinical microbiology laboratory. | 2013 | 23855986 |
| evaluation of luminex xtag gastrointestinal pathogen analyte-specific reagents for high-throughput, simultaneous detection of bacteria, viruses, and parasites of clinical and public health importance. | acute diarrheal disease (add) can be caused by a range of pathogens, including bacteria, viruses, and parasites. conventional diagnostic methods, such as culture, microscopy, biochemical assays, and enzyme-linked immunosorbent assays (elisa), are laborious and time-consuming and lack sensitivity. combined, the array of tests performed on a single specimen can increase the turnaround time (tat) significantly. we validated a 19plex laboratory-developed gastrointestinal pathogen panel (gpp) using l ... | 2013 | 23850948 |
| herd-level risk factors for campylobacter fetus infection, brucella seropositivity and within-herd seroprevalence of brucellosis in cattle in northern nigeria. | brucellosis and campylobacteriosis are economically important diseases affecting bovine reproductive efficiency in nigeria. a questionnaire-based survey was conducted in 271 cattle herds in adamawa, kaduna and kano states of northern nigeria using multistage cluster sampling. serum from 4745 mature animals was tested for brucella antibodies using the rose-bengal plate test and positives were confirmed in series-testing protocol using competitive enzyme-linked immunosorbent assay. preputial scrap ... | 2013 | 23830113 |
| meningitis and endocarditis caused by campylobacter fetus after raw-liver ingestion. | we report campylobacter fetus meningitis associated with endocarditis in a 75-year-old diabetic man after he consumed raw liver. c. fetus was isolated from blood samples and cerebrospinal fluid. cure was obtained with combined intravenous imipenem-gentamicin for 4 weeks; no relapse occurred after 6 months of follow-up. | 2013 | 23824770 |
| real time pcr to detect and differentiate campylobacter fetus subspecies fetus and campylobacter fetus subspecies venerealis. | bovine venereal campylobacter infection, caused by campylobacter fetus venerealis, is of significant economic importance to the livestock industry. unfortunately, the successful detection and discrimination of c. fetus venerealis from c. fetus fetus continue to be a limitation throughout the world. there are several publications warning of the problem with biotyping methods as well as with recent molecular based assays. in this study, assessed on 1071 isolates, we report on the successful develo ... | 2013 | 23811208 |
| evaluation of molecular assays for identification campylobacter fetus species and subspecies and development of a c. fetus specific real-time pcr assay. | phenotypic differentiation between campylobacter fetus (c. fetus) subspecies fetus and c. fetus subspecies venerealis is hampered by poor reliability and reproducibility of biochemical assays. aflp (amplified fragment length polymorphism) and mlst (multilocus sequence typing) are the molecular standards for c. fetus subspecies identification, but these methods are laborious and expensive. several pcr assays for c. fetus subspecies identification have been described, but a reliable comparison of ... | 2013 | 23810970 |
| cell extract-containing medium for culture of intracellular fastidious bacteria. | the culture of fastidious microorganisms is a critical step in infectious disease studies. as a proof-of-concept experiment, we evaluated an empirical medium containing eukaryotic cell extracts for its ability to support the growth of coxiella burnetii. here, we demonstrate the exponential growth of several bacterial strains, including the c. burnetii nine mile phase i and phase ii strains, and c. burnetii isolates from humans and animals. low-oxygen-tension conditions and the presence of small ... | 2013 | 23740722 |
| bacterial spectrum and antimicrobial susceptibility pattern of bloodstream infections in children with febrile neutropenia: experience of single center in southeast of turkey. | empirical antimicrobial therapy is usually started in febrile neutropenic patients without having culture results. the aim of this study was to help determine the policies of empirical antibiotic usage in febrile neutropenic children by detecting the antimicrobial susceptibility profile in this group of patients. in this study 811 blood cultures taken from neutropenic children hospitalized at the department of oncology of gaziantep children hospital november 2007 and february 2010 were retrospec ... | 2011 | 23729883 |
| bacterial spectrum and antimicrobial susceptibility pattern of bloodstream infections in children with febrile neutropenia: experience of single center in southeast of turkey. | empirical antimicrobial therapy is usually started in febrile neutropenic patients without having culture results. the aim of this study was to help determine the policies of empirical antibiotic usage in febrile neutropenic children by detecting the antimicrobial susceptibility profile in this group of patients. in this study 811 blood cultures taken from neutropenic children hospitalized at the department of oncology of gaziantep children hospital november 2007 and february 2010 were retrospec ... | 2011 | 23729883 |
| development and application of a real-time polymerase chain reaction method for campylobacter jejuni detection. | to develop a real-time polymerase chain reaction (pcr) method to detect and quantify campylobacter jejuni (c. jejuni) from stool specimens. | 2013 | 23716989 |
| nif-type iron-sulfur cluster assembly system is duplicated and distributed in the mitochondria and cytosol of mastigamoeba balamuthi. | in most eukaryotes, the mitochondrion is the main organelle for the formation of iron-sulfur (fes) clusters. this function is mediated through the iron-sulfur cluster assembly machinery, which was inherited from the α-proteobacterial ancestor of mitochondria. in archamoebae, including pathogenic entamoeba histolytica and free-living mastigamoeba balamuthi, the complex iron-sulfur cluster machinery has been replaced by an ε-proteobacterial nitrogen fixation (nif) system consisting of two componen ... | 2013 | 23589868 |
| aerobic growth of campylobacter in media supplemented with c3-monocarboxylates and c4-dicarboxylates. | experiments were conducted to examine aerobic growth of campylobacter spp. in basal media supplemented with c4-dicarboxylates (fumarate, succinate, or malate) and c3-monocarboxylates (pyruvate or lactate). basal medium was supplemented with 30 mm fumarate, succinate, or malate and 0 to 100 mm lactate or pyruvate; inoculated with 10(6) cfu/ml of campylobacter coli, campylobacter fetus, or campylobacter jejuni; then incubated aerobically at 37 °c for 72 h. optical density (od) of cultures was meas ... | 2013 | 23575134 |
| mycotic abdominal aneurysm caused by campylobacter fetus: a case report for surgical management. | we report a rare case of mycotic abdominal aortic aneurysm associated with campylobacter fetus. a 72-year-old male admitted to the hospital because of pain in the right lower quadrant with pyrexia. the enhanced abdominal computed tomography (ct) examination showed abdominal aortic aneurysm (aaa) measuring 50 mm in maximum diameter and a high-density area of soft tissue density from the right lateral wall to the anterior wall of the aorta. however, since the patient showed no significant signs of ... | 2011 | 23555431 |
| antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world? | hosts and bacteria have coevolved over millions of years, during which pathogenic bacteria have modified their virulence mechanisms to adapt to host defense systems. although the spread of pathogens has been hindered by the discovery and widespread use of antimicrobial agents, antimicrobial resistance has increased globally. the emergence of resistant bacteria has accelerated in recent years, mainly as a result of increased selective pressure. however, although antimicrobial resistance and bacte ... | 2013 | 23554414 |
| pelvic inflammatory disease. | 2013 | 23547062 | |
| campylobacter fetus sepsis in an immunocompetent patient with haematological complication. | campylobacter fetus sepsis is rare, especially among young, immunocompetent patients. we present the case of a 43-year-old man with a history of ulcerative colitis who was diagnosed with c fetus bacteraemia with endovascular manifestation. the patient was found to have a low vitamin k level and a high international normalised ratio, and developed deep vein thrombosis. the patient was fully recovered with oral antibiotic treatment, anticoagulation and supportive therapy. clinicians should be awar ... | 2013 | 23536648 |
| spatial and temporal epidemiology of bovine trichomoniasis and bovine genital campylobacteriosis in la pampa province (argentina). | the venereal diseases bovine trichomoniasis (bt) and bovine genital campylobacteriosis (bcg) cause economic losses in endemic areas like la pampa province in argentina, where beef cattle are usually managed extensively. this study used data compiled under a provincial programme for the control and eradication of bt and bgc (pce) to determine the spatio-temporal distribution of these diseases and identify spatial clusters. the study population comprised 29,178 non-virgin bulls drawn from 3766 her ... | 2013 | 23518247 |
| occurrence and characteristics of fastidious campylobacteraceae species in porcine samples. | this study investigated the prevalence and characteristics of campylobacteraceae including a range of fastidious species in porcine samples. over a thirteen month period caecal contents (n=402) and pork carcass swabs (n=401) were collected from three pork abattoirs and pork products (n=399) were purchased at point of sale in the republic of ireland. campylobacteraceae isolates were recovered by enrichment, membrane filtration and incubation in antibiotic free media under a modified atmosphere (3 ... | 2013 | 23474652 |
| occurrence and molecular characterization of reptilian campylobacter fetus strains isolated in taiwan. | the number of people who raise reptiles as pets has increased, but information about zoonotic campylobacter carried by reptiles is limited. a survey of zoonotic campylobacter species isolated from reptiles was undertaken to understand the possibility of this zoonotic bacterial pathogen causing human infection. a total of 179 fresh reptile fecal samples were collected from human-raised, pet shop and wild reptiles to survey the campylobacter species. basic biochemical reactions and 16s rrna gene s ... | 2013 | 23466328 |
| presence of campylobacter and arcobacter species in in-line milk filters of farms authorized to produce and sell raw milk and of a water buffalo dairy farm in italy. | the objectives of this study were to investigate the presence of campylobacter spp. and arcobacter spp. in dairy herds authorized for the production and sale of raw milk and in a water buffalo dairy farm, and to test the antimicrobial susceptibility of the isolates. a total of 196 in-line milk filters were collected from 14 dairy farms (13 bovine and 1 water buffalo) for detection of campylobacter spp. and arcobacter spp. by microbiological culture. for each farm investigated, 1 isolate for each ... | 2013 | 23453517 |
| an unusual cause of spontaneous bacterial peritonitis due to campylobacter fetus with alcoholic liver cirrhosis. | a 40-year-old man with severe alcoholic liver cirrhosis with a 2-day history of fatigue and abdominal pain was admitted. he reported eating sushi and sliced raw chicken a few days previously. his abdomen was distended, with shifting dullness. based on the patient's history, physical examination and the results of abdominocentesis, he was diagnosed as having spontaneous bacterial peritonitis; blood and ascitic fluid cultures were positive for campylobacter fetus. the patient was started on treatm ... | 2013 | 23417384 |
| the surface layer of tannerella forsythia contributes to serum resistance and oral bacterial coaggregation. | tannerella forsythia is an anaerobic, gram-negative bacterium involved in the so-called "red complex," which is associated with severe and chronic periodontitis. the surface layer (s-layer) of t. forsythia is composed of cell surface glycoproteins, such as tfsa and tfsb, and is known to play a role in adhesion/invasion and suppression of proinflammatory cytokine expression. here we investigated the association of this s-layer with serum resistance and coaggregation with other oral bacteria. the ... | 2013 | 23357386 |
| bacterial protein n-glycosylation: new perspectives and applications. | protein glycosylation is widespread throughout all three domains of life. bacterial protein n-glycosylation and its application to engineering recombinant glycoproteins continue to be actively studied. here, we focus on advances made in the last 2 years, including the characterization of novel bacterial n-glycosylation pathways, examination of pathway enzymes and evolution, biological roles of protein modification in the native host, and exploitation of the n-glycosylation pathways to create nov ... | 2013 | 23329827 |
| a fatal case of klebsiella pneumoniae mycotic aneurysm. | mycotic aneurysm is a serious clinical condition with significant morbidity and mortality. staphylococcus aureus and salmonella species are the most common causative pathogens. klebsiella pneumoniae was rarely reported as a possible pathogen causing mycotic aneurysm; therefore, we describe a k. pneumoniae-related fatal bacteremia mycotic aneurysm in a patient in spite of appropriate antimicrobial agents and surgical management. | 2011 | 23326694 |