Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| elbow, wrist, and hand surgery. | 2007 | 2223443 | |
| elbow, wrist, and hand surgery. | 2007 | 2223443 | |
| [thrombus propagation and venous drainage disturbance in cerebral sinus-vein thrombosis--38 autopsied cerebral sinus-vein thrombosis]. | 38 autopsied cases of cerebral sinus-vein thrombosis (csvt) in our institute were studied. in this study, special attention was paid for the evolution and fate of venous thrombus. 18 cases showed hemorrhagic infarction or intracerebral hematoma (group 1; g 1). in contrast, no cerebral parenchymal changes were observed in the other 20 cases (group 2; g 2). in 13 of 18 cases of g 1, superior sagittal sinus (sss) were thrombosed. 10 of these 13 cases showed thrombosed cerebral cortical veins (cv) o ... | 2007 | 2223271 |
| [thrombus propagation and venous drainage disturbance in cerebral sinus-vein thrombosis--38 autopsied cerebral sinus-vein thrombosis]. | 38 autopsied cases of cerebral sinus-vein thrombosis (csvt) in our institute were studied. in this study, special attention was paid for the evolution and fate of venous thrombus. 18 cases showed hemorrhagic infarction or intracerebral hematoma (group 1; g 1). in contrast, no cerebral parenchymal changes were observed in the other 20 cases (group 2; g 2). in 13 of 18 cases of g 1, superior sagittal sinus (sss) were thrombosed. 10 of these 13 cases showed thrombosed cerebral cortical veins (cv) o ... | 2007 | 2223271 |
| [diagnosis and surgical treatment of traumatic damage to the sinus of valsalva following penetrating wounds of the heart]. | the authors had three patients with traumatic damage of the sinus of valsalva, caused by penetrating injury of the thorax inflicted with a knife. the patients were brought to the clinic in a grave condition with decompensation of systemic and pulmonary circulation. the anomaly called for emergency surgical correction under conditions of extracorporeal circulation. the diagnosis was based on the complaints, medical history, clinical picture, the results of functional methods of examination includ ... | 2007 | 2223226 |
| [diagnosis and surgical treatment of traumatic damage to the sinus of valsalva following penetrating wounds of the heart]. | the authors had three patients with traumatic damage of the sinus of valsalva, caused by penetrating injury of the thorax inflicted with a knife. the patients were brought to the clinic in a grave condition with decompensation of systemic and pulmonary circulation. the anomaly called for emergency surgical correction under conditions of extracorporeal circulation. the diagnosis was based on the complaints, medical history, clinical picture, the results of functional methods of examination includ ... | 2007 | 2223226 |
| [cardiomyoplasty]. | the article analyses the current state of the problem of cardiomyoplasty as a new method for the treatment of patients with myocardial cardiac insufficiency. the authors show the experimental and clinical material on the possibility and efficacy of using skeletal muscles for improving myocardial contractility and raising the cardiac index. experience gained in our country (6 operations) in cardiomyoplasty in patients with severe form of ischemic heart disease is discussed. the authors used an or ... | 1990 | 2223224 |
| [cardiomyoplasty]. | the article analyses the current state of the problem of cardiomyoplasty as a new method for the treatment of patients with myocardial cardiac insufficiency. the authors show the experimental and clinical material on the possibility and efficacy of using skeletal muscles for improving myocardial contractility and raising the cardiac index. experience gained in our country (6 operations) in cardiomyoplasty in patients with severe form of ischemic heart disease is discussed. the authors used an or ... | 1990 | 2223224 |
| [a congenital esophagotracheal fistula in an adult]. | 2007 | 2223222 | |
| [a congenital esophagotracheal fistula in an adult]. | 2007 | 2223222 | |
| [lung cancer in women in moscow (epidemiology, etiology and surgical treatment)]. | in the studied period (1973-1987) the lung carcinoma morbidity rate among females of moscow, in general intensive indices (per 100,000 females), showed a tendency to reduce (18.4 in 1973 and 15.1 in 1987). a reverse tendency is mostly encountered in other countries. more than half of patients with lung carcinoma were over 70 years of age. the ratio of males with lung carcinoma to that of females grew from 3.0:1.0 in 1973-1977 to 3.6:1.0 in 1983-1987. in the period from 1979 to 1988, 380 females ... | 2007 | 2223213 |
| [lung cancer in women in moscow (epidemiology, etiology and surgical treatment)]. | in the studied period (1973-1987) the lung carcinoma morbidity rate among females of moscow, in general intensive indices (per 100,000 females), showed a tendency to reduce (18.4 in 1973 and 15.1 in 1987). a reverse tendency is mostly encountered in other countries. more than half of patients with lung carcinoma were over 70 years of age. the ratio of males with lung carcinoma to that of females grew from 3.0:1.0 in 1973-1977 to 3.6:1.0 in 1983-1987. in the period from 1979 to 1988, 380 females ... | 2007 | 2223213 |
| the involvement of the midbrain periaqueductal grey in the cardiovascular response to injury in the conscious and anaesthetized rat. | cell bodies within the periaqueductal grey (pag) of the midbrain of the propofol-anaesthetized rat were stimulated using the excitotoxin kainic acid. this resulted in a rise in arterial blood pressure and a tachycardia, together with a reduction in the sensitivity and a rightward resetting of the baroreflex. these changes mimicked the cardiovascular effect of bilateral hindlimb ischaemia in the rat. further experiments in conscious rats indicated that electrolytic lesions in the pag prevented th ... | 1990 | 2223051 |
| endogenous heparin-binding lectin activity in human placenta: purification and developmental expression. | human placental extracts contain a herapin-inhibitable lectin activity. the lectin, which closely resembles those from chicken and rat tissues, was purified by heparin-affinity chromatography. it shares many properties with the previously reported lectins, including hapten specificity, molecular weight of monomers, and immunological cross-reactivity. sections from different stages of placental development, stained by immunohistochemistry procedures using lectin-specific antibody, showed that the ... | 1990 | 2223005 |
| [fissure sealants: clinical study]. | a total of 132 sealants are applied to 55 children, over a period of one to five years. the results show a complete retention of 76.5%, a partial loss of 12.8% and complete loss of 10.6%. | 2007 | 2222644 |
| medicare denials: should you appeal? | 2006 | 2222561 | |
| penicillin binding proteins of vibrio cholerae. | eleven penicillin binding proteins (pbps) of vibrio cholerae have been identified using [125i] labelled p-hydroxybenzyl penicillin (penx). these proteins are localised in the inner membrane and have molecular weights ranging from 97,000 to 22,000. neutral hydroxylamine released the labelled penx from the pbps and pretreatment with cold benzyl penicillin inhibited labelling completely. the pbp 4 is the most sensitive target for cephaloridine and aztreonam. cephaloridine also binds to three other ... | 1990 | 2222436 |
| determination of the affinity of a steroid for its receptor is not sufficient to measure its intrinsic hormonal activity. | 2007 | 2219201 | |
| determination of the affinity of a steroid for its receptor is not sufficient to measure its intrinsic hormonal activity. | 2007 | 2219201 | |
| no room at the trough: an epitaph for the eighties. | 2008 | 2217593 | |
| [a comparative study of the oxidation processes in the cells of typical forms and l forms of vibrio cholerae]. | a comparative study of metabolic processes in cells of typical forms and l-forms of cholera vibrios has determined a change in the intensity of oxidative processes demonstrated through a decrease in the activity of respiration enzymes (dehydrogenases and diaphorases) and through a restricted transport of electrons along the respiration chain. the facts established evidence for the transition of l-transformed cells into a physiological state with a deficit of substrates and energy as well as with ... | 1990 | 2215284 |
| [the composition of a population of cloned cultures of revertant vibrio cholerae l forms]. | the process of l-transformation and l-transformed state duration have been studied for their effect on variability of main characters of revertant cultures of choleric vibrions l-forms at the population level with the use of cloned cultures of the choleric vibrions. the study was conducted on two strains of the choleric vibrion of the eltor biovar in different periods of storage in the l-transformed state (1, 3, 6 months). it has been revealed that characters of the species and biovar remained s ... | 1990 | 2215283 |
| mucilaginous plants and their uses in medicine. | throughout the world but especially in the tropical and subtropical zones, there are succulent and non-succulent plants which harbor readily releasable mucilage in their tissues, on the surface of their seeds or in their bark. this mucilage may have diverse practical uses. among these, it functions as a healing agent, casually or in the practice of traditional-folk or conventional medicine. the mucilage of some of these plants is well known to science and has been studied by pharmacologists and ... | 2008 | 2214811 |
| gorham's syndrome (massive osteolysis): a case report. | 2004 | 2213318 | |
| developing an educational needs assessment. | nurse educators routinely are asked to assess learning needs. step-by-step guidelines for formulating and implementing an educational needs assessment are provided. the nurse educator who is familiar with conducting a needs assessment can obtain required baseline information to make decisions in various situations. | 2005 | 2213212 |
| hormonal dependency of cerebral meningiomas. part 1: female sex steroid receptors and their significance as specific markers for adjuvant medical therapy. | female sex steroid receptors were examined in 50 human cerebral meningiomas. for estrogen receptors, high-affinity binding sites (dissociation constant (kd): 0.05 to 0.2 nm) were found in the cytosolic fraction with a capacity of less than 4 fmol/mg protein in 10 meningiomas using a dextran-coated charcoal (dcc) assay. in the same cytosolic fraction, the solid-phase enzyme immunoassay revealed only one cytosol with a positive colorimetric reaction equal to 5 fmol/mg protein. however, in the nucl ... | 1990 | 2213164 |
| place coding of vowel formants for cochlear implant patients. | four multiple-channel cochlear implant patients were tested with synthesized versions of the words "hid, head, had, hud, hod, hood" containing 1, 2, or 3 formants, and with a natural 2-formant version of the same words. the formant frequencies were encoded in terms of the positions of electrical stimulation in the cochlea. loudness, duration, and fundamental frequency were kept fixed within the synthetic stimulus sets. the average recognition scores were 47%, 61%, 62%, and 79% for the synthesize ... | 1998 | 2212290 |
| factors influencing the initiation of carious lesions in specific tooth surfaces over a 4-year period in children between the ages of 11-12 years and 15-16 years. | an analysis of factors influencing the initiation of carious lesions on specific tooth surfaces over a 4-year period in children between the ages of 11-12 years and 15-16 years is presented. approximately 1000 children, resident in the county of south glamorgan, wales, were assessed for caries status and oral cleanliness in 1980 when aged 11-12 years and again in 1984 when aged 15-16 years. on both occasions, the children completed detailed questionnaires on dental health-related topics. surface ... | 1998 | 2212201 |
| platelet activating factor-induced clinical and histopathologic responses in atopic skin and their modification by the platelet activating factor antagonist bn52063. | the clinical and histopathologic responses to intradermal platelet-activating factor (paf-acether) in atopic subjects, without evidence of atopic dermatitis are documented. an immediate acute wheal and flare reaction was observed in all volunteers. histopathologically, the reaction was characterized by a predominantly neutrophilic response, which was seen at 30 minutes and was maximal at 4 hours. eosinophils were observed in the infiltrate as early as 30 minutes after injection, and were maximal ... | 1998 | 2212123 |
| sense of coherence, life stress, and psychological distress: a prospective methodological inquiry. | antonovsky (1987) has proposed the sense of coherence (soc) as a global perceptual predisposition in responding to life stress. composed of comprehensibility, manageability, and meaningfulness, this construct has been associated with more adaptive coping in previous cross-sectional studies. this prospective study (n = 95) investigated the association of soc (assessed by antonovsky's measure) with life stress and symptoms. soc was correlated negatively with life stress and symptoms and appeared t ... | 2005 | 2212043 |
| depression and organic mood disorder. | 2008 | 2211553 | |
| the effect of cefuroxime axetil on the faecal flora of healthy volunteers. | the effect on the faecal flora of cefuroxime axetil, an oral ester of cefuroxime, was examined in ten healthy volunteers following a dose of 250 mg twice a day for 41/2 days. the mean blood concentration 2 h after the ninth dose was 3.6 mg/l and the urinary excretion was approximately 40% in 6 h and 50% in 24 h. two volunteers developed mild diarrhoea and one candida vaginitis. although there was variation between volunteers in the changes found in the faecal flora, the major effects were a redu ... | 1990 | 2211457 |
| synthesis and biological activity of 3-vinylthio- and 3-vinylthiomethylcephem derivatives. | the synthesis and biological properties of some 3-vinylthio- and 3-vinylthiomethylcephem derivatives are described. both series possess potent antibacterial activity. among them, 3-[(z)-2-cyanovinylthiomethyl]cephem derivative was found to have an expanded antibacterial spectrum. | 2008 | 2211378 |
| lytic effect of vibrio cholerae elastase on gram-positive and -negative bacteria. | elastase of vibrio cholerae caused the lysis of freshly grown cells of gram-negative (pseudomonas aeruginosa, proteus vulgaris, salmonella paratyphi a and klebsiella pneumoniae) bacteria. gram-positive (staphylococcus aureus and s. epidermidis) organisms were resistant to this enzyme. heat killed and lyophilized gram-positive and -negative bacteria (except s. aureus and s. epidermidis) showed higher sensitivity to elastase. both gram-negative and -positive bacteria were lyzed maximally by elasta ... | 1990 | 2210489 |
| calculation of the cytochrome p-450 redox potential from kinetic data by the marcus treatment; feasible or not? | using calculations based on the marcus theory (or linear approximations thereof) and existing rate constant/oxidation potential data, an attempt has been made to estimate the effective standard potential and reorganization energy of the p-450/(p-450)-.couple. due to the limited data basis, the results only qualitatively indicate that p-450 either must possess an extremely high eo'fe(v)/fe(iv) value (greater than 2.5 v!) or not act as an electron transfer oxidant at all. by similar calculations, ... | 2007 | 2206708 |
| information requirements--what does the profession need? | 2007 | 2206664 | |
| 'intravenous sedation in general dental practice--why oximetry?'. | 2007 | 2206650 | |
| [experimental study on the difference of ischemic threshold between cerebral cortex and thalamus with middle latency auditory evoked potentials]. | middle latency auditory evoked potentials (ml-aeps) have not yet been established as a device of assessing neurological events because their origins have not been definitely identified. in this study, we assessed the neurological usefulness of mla-eps through experimental approach using canine models of acute ischemia localized within the cerebral cortex or thalamus. two types of localized cerebral ischemia were produced in mongrel dogs by clipping of major cerebral arteries and inducing of hypo ... | 1990 | 2206636 |
| 4-methylumbelliferyl-alpha-glycosides of partially o-acetylated n-acetylneuraminic acids as substrates of bacterial and viral sialidases. | 4-o-acetylated, 7-o-acetylated, and 9-o-acetylated 4-methylumbelliferyl-alpha-n-acetyl-neuraminic acids (neu4,5ac2-mu, neu5,7ac2-mu, neu5,9ac2-mu) were tested as substrates of sialidases of vibrio cholerae and of clostridium perfringens. both sialidases were unable to hydrolyse neu4,5ac2-mu. this compound at 1 mm concentration did not inhibit significantly the cleavage of neu5ac-mu, the best substrate tested. the 4-o-acetylated sialic acid glycoside is hydrolysed slowly by the sialidase from fow ... | 1990 | 2206459 |
| detection of vibrio cholerae o1 in the aquatic environment by fluorescent-monoclonal antibody and culture methods. | vibrio cholerae o1 in plankton samples collected from ponds and rivers between february 1987 and january 1990 in matlab, bangladesh, was detected by the fluorescent-monoclonal antibody (fa) technique. samples were collected at sites which were monitored fortnightly (fixed sites) as well as at sites that were part of a case-control study. fa results were compared with those obtained by conventional culture methods (cm). a total of 876 samples were collected; v. cholerae o1 was detected in 563 sam ... | 1990 | 2206100 |
| development of an in vitro model for study of non-o1 vibrio cholerae virulence using caco-2 cells. | non-o1 vibrio cholerae strains have been reported as a causative agent of diarrhea throughout the world. we recently reported that non-o1 v. cholerae strains cause diarrhea in human volunteers. in this study we evaluated the virulence of three strains of non-o1 v. cholerae in a caco-2 cell adherence assay by light and electron microscopy. a-5 is an environmental isolate which failed to colonized volunteers and did not cause diarrhea. it exhibited low numbers of organisms adherent to caco-2 cells ... | 1990 | 2205582 |
| vibrio cholerae hlya hemolysin is processed by proteolysis. | the leukocidal activity of the vibrio cholerae hemolysin (hlya) was utilized to detect, enrich, and clone hybridoma cells expressing neutralizing monoclonal antibody in a new survivor selection protocol. a bank of 550 hybridoma clones was obtained from a mouse immunized with hemolysin by using standard techniques. the hybridoma bank was treated with a dose of hlya hemolysin lethal to nonimmune clones. five surviving hybridoma clones (x1 through x5) which possessed anti-hlya activity were obtaine ... | 1990 | 2205579 |
| cloning and nucleotide sequence of a heat-stable enterotoxin gene from vibrio cholerae non-o1 isolated from a patient with traveler's diarrhea. | we determined the nucleotide sequence of the heat-stable enterotoxin (sta) gene of the vibrio cholerae non-o1 strain nrt36 isolated from a patient with traveler's diarrhea. the gene is chromosomally encoded and the presumed product is 78 amino acids in length, with a molecular weight of 8,814, though the genes of escherichia coli sta(s) (sth and stp) are encoded in plasmid dna and both products are 72 amino acids in length. the first 18 amino acids at the nh2 terminus were hydrophobic, suggestin ... | 1990 | 2205577 |
| a double-blind, controlled trial of bioflorin (streptococcus faecium sf68) in adults with acute diarrhea due to vibrio cholerae and enterotoxigenic escherichia coli. | the therapeutic efficacy of bioflorin (streptococcus faecium sf68; gipharmex, milan, italy) in acute watery diarrhea was evaluated in 183 bangladeshi adults. vibrio cholerae organisms were isolated from stool cultures in 114 patients, and enterotoxigenic escherichia coli organisms were isolated in 41. in addition to iv rehydration, patients were randomly assigned to receive either capsules of bioflorin containing 1 x 10(9) of live sf68 or capsules of placebo containing killed sf68 once every 8 h ... | 1990 | 2203662 |
| survival of aeromonas hydrophila and escherichia coli in aquatic environments. | survival of aeromonas hydrophila and escherichia coli in distilled water, pond water and effluents of anaerobic digesters were examined. survival capabilities of a. hydrophila in various aquatic systems were similar to e. coli except in the raw effluents of anaerobic digesters, where a. hydrophila survived significantly better than e. coli for 6 days. pathogens such as staphylococcus aureus, salmonella enteritidis and vibrio cholerae were readily killed in the raw effluents of the anaerobic dige ... | 1990 | 2203637 |
| development of vaccines against cholera and diarrhoea due to enterotoxigenic escherichia coli: memorandum from a who meeting. | this memorandum summarizes current knowledge on the epidemiology of cholera and diarrhoea due to enterotoxigenic escherichia coli (etec) and outlines the results of recent research to develop an effective oral vaccine against cholera. the meeting reviewed current research on the protective antigens of etec and made a number of recommendations with the aim of stimulating further efforts towards the development of vaccines against disease caused by etec. | 1990 | 2203550 |
| from the national institute of allergy and infectious diseases. summary of the 25th united states-japan joint conference on cholera and related diarrheal diseases. | 1990 | 2201739 | |
| [morphological changes caused by the dermonecrosis factor of the causative agents of cholera and various other intestinal infections]. | intra- or subepithelial focal purulent inflammation with necrosis of exudating leucocytes during 1-2 days is developed in consequence of intradermal injection of the living cholera vibrios, cultured on membrane agar, or their supernatants. sometimes coagulative necrosis of cover epithelium arises without preliminary purulent inflammation stage from the very beginning. intradermal injection of living cholera vibrios leads to the development of coagulative necrotic foci in derma too. the vascular ... | 1990 | 2201411 |
| screening of aquatic samples for vibrio cholerae serotype o1 by a dot-blot method and a latex agglutination test. | a dot-blot, enzyme-linked immunosorbent method and a latex agglutination test were studied for their abilities to detect vibrio cholerae serotype o1 in aquatic samples by testing artificially contaminated water as well as samples from natural potential sources. water samples were preenriched with alkaline peptone and then enriched with monsur peptone water. for the dot-blot test, enriched cultures of organisms in a small portion of the monsur peptone water were transferred to a polyvinylidene di ... | 1990 | 2200338 |
| immunochemistry and comparative insect (neuro) endocrinology. | 1995 | 2200010 | |
| isolation, characterization, and host-cell-binding properties of a cytotoxin from campylobacter jejuni. | a 68,000-molecular-weight protein was isolated by polyacrylamide gel electrophoresis from the organism-free filtrate of a fully virulent clinical strain of campylobacter jejuni. the eluted protein was heat labile, was inactivated at either ph 3.0 or 9.0, was sensitive to trypsin, and was lethal for fertile chicken eggs. it also had toxic effects on chicken embryo fibroblast, chinese hamster ovary (cho), and intestinal 407 (int407) cells. a monoclonal antibody (cetpmab4) raised to this eluted tox ... | 1990 | 2199497 |
| effects of ursodeoxycholic acid on gallbladder contraction and cholecystokinin release in gallstone patients and normal subjects. | it has been previously suggested that treatment with ursodeoxycholic acid leads to decreased gallbladder emptying. the proposed mechanism is decreased release of cholecystokinin through negative feedback control by an increased amount of intraduodenal bile acids. in the present study we examined cholecystokinin release and gallbladder contraction after oral administration of a commercial fatty meal (sorbitract; dagra, diemen, the netherlands) using ultrasonography in eight normal subjects and ei ... | 2007 | 2199291 |
| effects of ursodeoxycholic acid on gallbladder contraction and cholecystokinin release in gallstone patients and normal subjects. | it has been previously suggested that treatment with ursodeoxycholic acid leads to decreased gallbladder emptying. the proposed mechanism is decreased release of cholecystokinin through negative feedback control by an increased amount of intraduodenal bile acids. in the present study we examined cholecystokinin release and gallbladder contraction after oral administration of a commercial fatty meal (sorbitract; dagra, diemen, the netherlands) using ultrasonography in eight normal subjects and ei ... | 2007 | 2199291 |
| structural studies on the subunits of glutamate synthase from azospirillum brasilense. | the amino acid composition and the n-terminal sequences of the two dissimilar subunits of glutamate synthase from azospirillum brasilense have been determined along with the sequences of selected cnbr peptides. comparison of our data with those available for escherichia coli glutamate synthase revealed an overall good homology between the enzymes from the two sources. this is more evident for the heavy subunits where the highly conserved n-terminal sequence containing cys-1, suggests that this r ... | 1990 | 2198943 |
| the essential region for assembly and particle formation in hepatitis b virus surface antigen produced in yeast cells. | the hepatitis b virus (hbv) genome carries a hbv surface antigen (hbsag) gene that can encode a polypeptide of 226 amino acids (aa). this gene can be expressed in the yeast, saccharomyces cerevisiae, and the products can be assembled into 22-nm particles indistinguishable from those recovered from a patient's serum. we constructed a set of deletion derivatives of the hbsag gene, and examined the particle-forming ability of the resulting polypeptides by expressing the gene in yeast. elimination o ... | 1990 | 2197186 |
| expression in escherichia coli of two mutated genes encoding the cholera toxin b subunit. | to allow subsequent genetically mediated fusion of foreign antigens to cholera toxin b subunit (ctb), two mutated ctb encoding genes (ctxb) were constructed and overexpressed in escherichia coli. the signal peptide coding sequence was deleted and restriction sites were created at both ends of the modified sequence. both synthesized ctbs contain additional amino acid(s) at the n terminus (one and three). they were purified as insoluble products and refolded into the natural pentameric ctb structu ... | 1990 | 2197181 |
| randomised double blind trial of single dose doxycycline for treating cholera in adults. | to compare the efficacy of a single dose of doxycycline (200 or 300 mg) with the standard multiple doses of tetracycline in patients with cholera. | 1990 | 2196962 |
| noninvasive imaging of the superficial femoral artery using ultrasound duplex scanning. | a total of 56 lower extremities in 28 patients were evaluated by both conventional arteriography and ultrasound duplex scanning. overall sensitivity for duplex scanning compared to arteriography in detecting stenotic or occlusive disease was 91%, specificity was 94%, positive predictive value 85% and negative predictive value 97%. results for duplex scanning were better in the proximal and middle segment compared to the distal third of the superficial femoral artery. the sensitivity of segmental ... | 1997 | 2196267 |
| [the capacity to produce cholera exotoxin in natural strains of vibrio cholerae]. | the study of 27 v. cholerae strains, isolated from cholera patients and found to be hemolytically inactive, with a view to establish their capacity for the production of cholera toxin has revealed that 4 strains (v. cholerae cholerae dacca 35, v. cholerae cholerae dacca 3, v. cholerae cholerae b1307, v. cholerae cholerae j89) produce this protein. the quantitative determination of enterotoxin has been made with the use of gm1 elisa technique. strain dacca 35 has been found to be highly toxigenic ... | 1990 | 2195813 |
| ischemic stroke due to protein c deficiency. | plasma protein c exerts anticoagulatory effects by inactivating factors v and viii. hereditary protein c deficiency is transmitted as an autosomal dominant disorder. homozygous individuals usually develop purpura fulminans as newborns; heterozygous protein c-deficient individuals are at increased risk for venous thrombosis and pulmonary embolism. however, arterial thrombosis has been only rarely observed. we describe a young patient with heterozygous protein c deficiency who experienced a severe ... | 1999 | 2195715 |
| [the problem of the effectiveness of condoms against hiv infection]. | in several countries the condom is recommended as the most important protection against hiv infection, although there is no proof that the condom is effective against sexually transmitted diseases (std). prior to the hiv epidemic the condom was used to prevent pregnancy and to decrease the risk of std. to prevent a deadly infection such as that with hiv, safe ways of protection are mandatory. recent studies on hiv prevention show the assumption that condoms provide reliable protection against hi ... | 1990 | 2195654 |
| screening for neurotoxicity: complementarity of functional and morphologic techniques. | our philosophy is that screening tests should be applicable across species and emphasize complementarity to neuropathology. within this context, electrophysiological tests comparable to those in human clinical neurology are powerful screening tools. for example, while histopathologic evaluation of the cochlea for ototoxicity is difficult, evoked potential audiometry is fast and easy. in this instance, one might routinely screen for deficits in auditory function, and reserve morphologic technique ... | 1990 | 2195632 |
| benign pulmonary lesions that may be misdiagnosed as malignant. | five benign pulmonary lesions that may be misdiagnosed as malignant tumors are reviewed. in three lesions, diagnostic problems arise when a spindle cell component is dominant and obscures other characteristic histologic features. in the inflammatory pseudotumor, correct diagnosis relies on recognition of the benign cytology of the spindle cells and identifying a typical admixture of plasma cell-rich inflammatory cells. for spindle cell carcinoids, useful diagnostic features are the organoid patt ... | 2002 | 2194259 |
| localization of septation sites. | 1990 | 2194250 | |
| suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids. | autoxidation of certain polyunsaturated fatty acids (pufa) produces 4-hydroxy-2-nonenal (hne). of all of the many products produced during pufa autoxidation, hne is one of the more interesting. it is remarkably cytotoxic, and appears to play a role in certain types of pathology. this manuscript suggests, for the first time, mechanisms that rationalize the production of hne from pufa that undergo autoxidation. the mechanisms require, in agreement with the facts, an n-6 fatty acid and iron catalys ... | 2003 | 2193853 |
| double-blind, randomized, controlled clinical trial of norfloxacin for cholera. | in a double-blind, randomized clinical trial with 78 adults with acute watery diarrhea and severe dehydration, 37 subjects were positive for vibrio cholerae. in conjunction with rehydration therapy, 13 patients received norfloxacin, 12 received trimethoprim-sulfamethoxazole (tmp-smx), and 12 received a placebo. norfloxacin was superior to tmp-smx and to the placebo in reducing stool output, duration of diarrhea, fluid requirements, and vibrio excretion. tmp-smx was no better than the placebo. | 1990 | 2193628 |
| direct effect of parathyroid hormone on insulin secretion from pancreatic islets. | indirect evidence indicates that parathyroid hormone (pth) interacts with pancreatic islets and modulates their insulin secretion. this property of pth has been implicated in the genesis of impaired insulin release in chronic renal failure. we examined the direct effect of pth-(1-84) and pth-(1-34) on insulin release using in vitro static incubation and dynamic perifusion of pancreatic islets from normal rats. both moieties of the hormone stimulated in a dose-dependent manner glucose-induced ins ... | 1990 | 2193536 |
| hepatic apo b-100 lipoproteins and plasma ldl heterogeneity in african green monkeys. | the contribution of hepatic apolipoprotein (apo) b-100 lipoproteins to plasma low-density lipoprotein (ldl) metabolic heterogeneity was examined in african green monkeys. hepatic 3h-labeled very low-density lipoproteins (vldl) (d less than 1.006, where d is density in g/ml) or hepatic 131i-labeled ldl (1.030 less than d less than 1.063) were isolated from perfused livers and injected simultaneously with autologous plasma 125i-ldl into african green monkeys. serial blood samples were taken, and t ... | 1990 | 2193530 |
| hydramnios in twin pregnancy. | 2001 | 2193520 | |
| [inhibition of enteropathogens by clostridium butyricum miyairi 588]. | the inhibitory effect of clostridium butyricum miyairi 588 against various enteropathogens was investigated in mixed cultures. it was observed that c. butyricum m588 inhibited the growth of vibrio cholerae o1, v. cholerae non-o1, aeromonas hydrophila, and shigella flexneri. considering that the interaction between c. butyricum and shigella is especially important because of their proliferation site in the lower intestine, further examinations were carried out on shigella in particular. results w ... | 1990 | 2193065 |
| no acquisition of metastatic capacity of r1h rhabdomyosarcoma upon transfection with c-ha-ras oncogene. | the effect of the activated c-ha-ras oncogene on invasiveness and formation of spontaneous metastases was studied using the rhabdomyosarcoma r1h of the rat. r1h tumor cells which are able to grow in vitro and produce tumors upon subcutaneous injection in syngeneic wag/rij rats were transfected with the c-ha-ras (ej) oncogene and the neomycin gene for selection. two r1h cell lines harboring and expressing the human c-ha-ras oncogene, one cell line containing the neomycin gene only, and the parent ... | 1990 | 2192992 |
| amino-terminal sequence of the 21 kda apoprotein of a minor light-harvesting pigment-protein complex of the photosystem ii antenna (lhc iid/cp24). | the 21 kda apoprotein of lhc iid, a minor light-harvesting antenna component of photosystem ii, has been isolated and subjected to n-terminal protein sequencing. a sequence of 66 residues was obtained which contains regions of considerable homology to both those reported for lhc ii and lhc i, but which is obviously distinct from them. the proposed occurrence of an identical 21 kda lhc subunit in both photosystems i and ii is shown to be incorrect. | 1999 | 2192916 |
| advances in the treatment of dilated cardiomyopathy. | the nursing care of the patient with dilated cardiomyopathy focuses on (1) improving right and left heart function, i.e., titrating vasoactive drugs to maintain acceptable cardiac index with minimum side effects (and/or monitoring the operation of a left ventricular assist device when left heart function is refractory to vasoactive drugs), (2) reducing cardiac filling pressures with diuretics, vasodilators, and/or restriction of dietary sodium, oral and iv fluids, (3) maintaining optimum oxygena ... | 2008 | 2192756 |
| factors influencing semen quality in pigs. | 1990 | 2192031 | |
| carrier detection of the x-linked primary immunodeficiency diseases using x-chromosome inactivation analysis. | carrier detection of three of the x-linked primary immunodeficiency diseases (x-linked agammaglobulinemia, x-linked severe combined immunodeficiency disease, and the wiskott-aldrich syndrome) is possible by analyzing patterns of x-chromosome inactivation in those cells affected by the disorder. normal women have balanced patterns of x-chromosome inactivation; that is, in a given population of cells, approximately half of their active x chromosomes are of paternal origin and half of their active ... | 1995 | 2191994 |
| binding of bacteria to carbohydrates immobilized on beads to demonstrate the presence of cell-associated hemagglutinins in vibrio cholerae. | we describe a phase contrast microscopy method for direct observation of classical and el tor vibrios to agarose beads containing covalently attached l-fucose or d-mannose. binding of the vibrios to l-fucose beads was found to correlate with fucose-sensitive agglutination of human o erythrocytes, while binding of bacteria to beads with d-mannose was consistent with mannose-sensitive agglutination of chicken erythrocytes. furthermore, vibrios expressing both fucose and mannose-sensitive hemagglut ... | 1990 | 2191694 |
| vibrio cholerae serogroup o1 in northeast thailand. | strains of vibrio cholerae serogroup o1 biotype el tor that are susceptible to mukerjee cholera bacteriophage group iv (s. mukerjee, bull. w.h.o. 28:333-336, 1963) were found. cholera vibrios isolated from epidemics in northeast thailand were characterized, and 57 of 60 strains isolated in 1986 were susceptible to cholera phage iv. however, all 113 strains isolated in 1988 were not susceptible to the phage. all isolates in both epidemics revealed behaviors typical of el tor vibrios, except phage ... | 1990 | 2191009 |
| construction of a bivalent oral vaccine for prevention of typhoid fever and cholera diarrhea. | a recombinant plasmid pmm-ctb containing the gene for production of the nontoxic b subunit of vibrio cholera was transferred into a safe, effective and attenuated oral vaccine ty21a strain of salmonella typhi. the resulting ty21a (pmm-ctb) could steadily produce ct-b subunit that was secreted extracellularly and had the same antigenicity as ct-b produced by v. cholera. furthermore, the characteristics of the antigenicity, the persistance in mice and the galactose sensitivity possessed in the str ... | 1990 | 2190570 |
| diabetes mellitus, the renin-angiotensin system, and angiotensin-converting enzyme inhibition. | many traditional antihypertensive drugs are linked to various effects that may cause concern in the hypertensive diabetic patient. the favorable tolerability of angiotensin-converting enzyme (ace) inhibitors in essential hypertension makes it likely that they will be well tolerated when used in diabetic patients. data from ongoing studies support the theory that ace inhibitors lower blood pressure to the same extent in hypertensive diabetics as in patients with essential hypertension. ace inhibi ... | 1990 | 2189073 |
| a novel autoregulatory cytokine is required for the regulation of autoaggressive responses. | limiting dilution studies indicate that cells with the potential to lyse autologous target cells exist in the peripheral blood of all normal individuals. in contrast to allocytotoxic cells, autocytolytic cells are down-regulated by a second less frequent cell population. when recombinant interleukin 2 is substituted for crude lymphocyte conditioned medium in these limiting dilution experiments, autocytotoxicity develops normally. under these conditions, however, the autocytotoxic response is not ... | 1990 | 2187837 |
| high- and low-density lipoproteins enhance infection of trypanosoma cruzi in vitro. | trypanosoma cruzi exhibits a developmentally regulated neuraminidase activity that is inhibited by high-density lipoprotein (hdl). we report here that the infection of culture cells by t. cruzi trypomastigotes is enhanced by hdl in a dose-dependent manner. the enhanced infection is prevented by vibrio cholerae neuraminidase, an enzyme whose activity is not inhibited by hdl, suggesting that sialic acid is involved in t. cruzi-host interaction. similar enhancement of infection is also produced by ... | 1990 | 2183047 |
| [cholestyramine adsorbs escherichia coli and vibrio cholerae toxins by way of ion exchange mechanism]. | the use of cholestyramine in the treatment of enterocolitis is justified by its ability to fix the lt toxin of vibrio cholerae and etec, the st toxin of etec and the verotoxin of ehec at the ph of intestinal fluid. to elucidate the nature of the ion-exchange mechanism in the binding of the toxins on the resin, we try to eluate the toxins with 0.1 m to 0.9 m nacl solution at ph 7. irrespective of their presence or absence in the different fractions, the biological activity of the toxins was asses ... | 1990 | 2181919 |
| [comparative evaluation of clinical and economic effectiveness of preventive therapy of affective and schizoaffective psychoses]. | the authors provide the results of a comparative study into the action of different drug approaches to the prevention of relapses of affective and schizoaffective psychoses with the aid of multifactorial consideration of different clinical, economic and socioeconomic indicators characterizing the "benefits and losses" because of the use of carbamazepine and lithium carbonate. the comparative analysis has shown a high normothymic activity of carbamazepine and lithium carbonate in the patients exa ... | 2007 | 2176049 |
| [osmotic homeostasis and blood rheology in patients in the acute period of ischemic cerebral infarction]. | the authors describe the role of changes in osmotic homeostasis and hemorheology in the pathogenesis of ischemic brain stroke. 48 patients experiencing an acute period of ischemic brain stroke were examined. for this purpose the following methods were employed: measurements of blood, urine and csf osmolality by knauer osmometer; glucose and urea by the enzymatic assay; blood electrolytes by flame photometer; aggregation of platelets, red blood cells, blood viscosity, fibrinogen, hematocrit; the ... | 2007 | 2175076 |
| a new selective, differential agar medium for isolation of vibrio cholerae o1: pmt (polymyxin-mannose-tellurite) agar. | a new selective and differential agar medium, polymyxin-mannose-tellurite (pmt) agar was devised to differentiate easily colonies of vibrio cholerae o1 from those of v. cholerae non-o1. the differentiation between colonies of the two vibrios is based on mannose-fermentation. colonies of v. cholerae o1 on the agar are agglutinated with o1 antiserum of v. cholerae much more easily than those on thiosulfate-citrate-bile salts-sucrose (tcbs) agar. | 1990 | 2175000 |
| study population in support: patients (as defined by disease categories and mortality projections), surrogates, and physicians. | 2008 | 2174967 | |
| transcriptional regulation by iron of a vibrio cholerae virulence gene and homology of the gene to the escherichia coli fur system. | we have previously described an iron-regulated virulence determinant in vibrio cholerae. strain mbg40, which contains a tnphoa insertion mutation in the iron-regulated gene irga, has reduced virulence in a newborn mouse model and has lost the major 77-kda iron-regulated outer membrane protein. we report here the cloning of the irga'-'phoa gene fusion, the sequencing of the 5'-proximal portion of irga, and the definition of its promoter region by primer extension. the deduced amino acid sequence ... | 1990 | 2174861 |
| two-step processing for activation of the cytolysin/hemolysin of vibrio cholerae o1 biotype el tor: nucleotide sequence of the structural gene (hlya) and characterization of the processed products. | vibrio cholerae o1 biotype el tor produces and secretes a 65-kda cytolysin/hemolysin into the culture medium. we cloned the structural gene (hlya) for the cytolysin from the total dna of a v. cholerae o1 el tor strain, n86. nucleotide sequence analysis of hlya revealed an open reading frame consisting of 2,223 bp which can code for a protein of 741 amino acids with a molecular weight of 81,961. consistent with this, a 79-kda protein was identified as the product of hlya by maxicell analysis in e ... | 1990 | 2174833 |
| a nontraditional role for water in the cytochrome c oxidase reaction. | the passage of electrons through cytochrome c oxidase is directly related to the activity of water. reducing the activity in a system containing reductant, oxygen, and cytochrome oxidase blocks electron transfer between reduced cytochrome a and oxidized cytochrome a3. the extent of the block is directly related to the osmotic pressure of the system, implying that the protein shell of the oxidase acts as a semipermeable membrane that excludes osmotic perturbants but not water. it appears that app ... | 1990 | 2174258 |
| cytomegalovirus-induced pneumonitis and myocarditis in newborn mice. a model for perinatal human cytomegalovirus infection. | genetically determined resistance to the lethal effects of infection with murine cytomegalovirus (mcmv) has been reported previously in adult and newborn mice. we examined the pathogenesis of mcmv infection in resistant (cba, h-2k) and susceptible (balb/c, h-2d) mice infected intraperitoneally on the day of birth. balb/c mice developed a severe interstitial pneumonitis and myocarditis 10 days post-infection. their pulmonary and tissues contained high mcmv titres and large numbers of mcmv-antigen ... | 1990 | 2174234 |
| [percutaneous atherectomy of the pelvic and leg arteries]. | percutaneous atherectomy, using a simpson atherectomy catheter, was performed in 70 patients (43 men, 27 women) whose average age was 72 years (range 42 to 87 years). between june 1988 and july 1989 all patients with disease in suitable localisations were treated in this way. the doppler sonographic index before treatment was 0.6 (sd = 0.15), after treatment 0.89 (sd = 0.13). recurrence was 21% after six months and 29% after twelve months. atherectomy is superior to balloon dilation in the treat ... | 2002 | 2173060 |
| evidence for a role of the na+/h+ exchanger in the colony-stimulating-factor-induced ornithine decarboxylase activity and proliferation of the human cell line m-07e. | the subclone m-07e, derived from the interleukin-3 (il-3)-responsive human myeloid cell line m-07, is strictly dependent on either il-3 or granulocyte-macrophage-colony-stimulating factor (gm-csf) for its growth and survival. this cell line may be regarded as a candidate model to investigate the poorly understood events triggered by growth factors binding to human hemopoietic cells. both il-3 and gm-csf induce in m-07e cells an increase of ornithine decarboxylase (odc) activity, which reaches it ... | 1990 | 2170428 |
| osteoblasts display receptors for and responses to leukemia-inhibitory factor. | specific binding of leukemia-inhibitory factor (lif) to osteoblasts, but not multinucleated osteoclasts, was demonstrated by receptor autoradiography by using cells isolated from newborn rat long bones. the clonal rat osteogenic sarcoma cells, umr 106-06, which have several phenotypic properties of osteoblasts, expressed 300 lif receptors per cell, with an apparent kd of 60 pm. treatment of calvarial osteoblasts or umr 106-01 cells with lif resulted in a dose-dependent inhibition of plasminogen ... | 1990 | 2170427 |
| effects of a novel 21-amino steroid, u74006f, on the rat pituitary-adrenocortical axis. | the 21-amino steroid u74006f is a potent inhibitor of lipid peroxidation and has been shown to affect beneficially the acutely injured central nervous system. therapeutically, it is desirable for this compound to be devoid of steroid side-effects. we have demonstrated a significant (p less than 0.001) inhibition of basal acth secretion from cultured rat pituitary cells during a 24-h incubation at concentrations (10-100 mumols/l) previously demonstrated to inhibit lipid peroxidation in vitro. u74 ... | 1990 | 2169520 |
| photoprotective effect of superoxide-scavenging antioxidants against ultraviolet radiation-induced chronic skin damage in the hairless mouse. | albino hairless mice (skh:hr-1) exposed chronically to suberythemal doses of ultraviolet radiation develop visible skin changes, histological alterations, and tumors. topical treatment of mice with solutions of superoxide-scavenging antioxidants (such as alpha-tocopherol, ascorbic acid, propyl gallate and trolox) prior to each uvb radiation exposure reduced significantly the severity of these events. tocopherol esters and ascorbyl palmitate were not as effective as the parent compounds in provid ... | 1990 | 2169296 |
| pertussis toxin b-subunit-induced ca2(+)-fluxes in jurkat human lymphoma cells: the action of long-term pre-treatment with cholera and pertussis holotoxins. | the exotoxins of bordetella pertussis and vibrio cholera have been used to investigate signal transduction in the human t-cell lymphoma jurkat. stimulation of the cells, leading to an increase in cytoplasmic free calcium, could be achieved by the anti-t-cell receptor complex antibody okt3 and by pertussis holotoxin (ptht), or its b-subunit (ptb), but not by cholera holotoxin (ctht) or its b-subunit (ctb). both holotoxins adp-ribosylated specifically g-proteins in the plasma membrane of intact ce ... | 1990 | 2169284 |
| [the effect of glycine and gamma-aminobutyric acid on the evoked activity of the spinal cord motor neurons in the lamprey]. | the influence of bath application of glycine (10(-5)-10(-3) mol/l) and gamma-aminobutyric acid (10(-5)-10(-2) mol/l) on the monosynaptic epsps evoked in motoneurons by stimulation of a descending tract and individual müller axons was studied in spinal cord-notochord preparation of lamprey (lampetra fluviatilis). both amino acids hyperpolarized the motoneuron membrane and depressed the evoked synaptic activity. but the inhibitory effect of glycine was stronger and it was revealed at lower concent ... | 2007 | 2169033 |
| ebna size polymorphism can be used to trace epstein-barr virus spread within families. | the epstein-barr virus (ebv)-determined nuclear antigens ebna 1, 2, 3, 4, and 6, regularly expressed in ebv-transformed lymphoblastoid cell lines, vary in size among viral strains. we have used this characteristic to trace the spread of the virus within seven families by using an approach called ebnotyping. among 33 evaluable individuals, 3 were ebv seronegative, and 17 different ebv strains could be isolated from the peripheral blood or throat washes of the remaining 30. all unrelated persons c ... | 1990 | 2168960 |
| primary multifocal angiosarcoma of the breast. sonographic evaluation with pathologic correlation. | 2007 | 2168955 | |
| low-energy laser irradiation--a new measure for suppression of arachidonic acid metabolism in the optic nerve. | helium-neon low-energy laser (lel) irradiation, known for its therapeutic effects in arthritis, wound healing, and muscular strain, was applied to eyes of rats that had sustained an optic nerve crush injury. crush injury to the optic nerve resulted in a long-lasting in vitro elevation of prostaglandin e2 (pge2) production (1.8-3.9-fold above control values during the 12 day study period). lel irradiation per se had no effect in vitro on pge2 production by the optic nerve; however, lel irradiatio ... | 1990 | 2168952 |