Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| extra-amniotic pregnancy. a trip to the extraembryonic coelom. | 2008 | 2277404 | |
| [anticancer effect of high voltage pulses combined with concentration dependent anticancer drugs on lewis lung carcinoma, in vivo]. | using high voltage pulse (initial electric field strength 3kv/cm, duration 4 msec, applied energy 14.9 joule) as a local load, and concentration dependent anticancer drugs such as peplomycin (pep) 20 mg/kg, cyclophosphamide (cpa) 100 mg/kg, mitomycin c (mmc) 3 mg/kg and cisplatin (cddp) 5 mg/kg administrated intraperitoneally, the effects on the suppression of primary lesions and on formation of pulmonary metastasis in the spontaneous pulmonary metastatic system of lewis lung carcinoma were inve ... | 2007 | 2277215 |
| [anticancer effect of high voltage pulses combined with concentration dependent anticancer drugs on lewis lung carcinoma, in vivo]. | using high voltage pulse (initial electric field strength 3kv/cm, duration 4 msec, applied energy 14.9 joule) as a local load, and concentration dependent anticancer drugs such as peplomycin (pep) 20 mg/kg, cyclophosphamide (cpa) 100 mg/kg, mitomycin c (mmc) 3 mg/kg and cisplatin (cddp) 5 mg/kg administrated intraperitoneally, the effects on the suppression of primary lesions and on formation of pulmonary metastasis in the spontaneous pulmonary metastatic system of lewis lung carcinoma were inve ... | 2007 | 2277215 |
| antenatal diagnosis of parenti-fraccaro type achondrogenesis. | 2008 | 2276781 | |
| arthritis disability, depression, and life satisfaction among black elderly people. | this study examined the correlates of arthritis disorder in a sample of black elderly people in nashville, tennessee. more specifically, both the presence of arthritis and its severity were examined with regard to level of depression and life satisfaction, particularly in the areas of family life, social support, and leisure activities. data were collected through face-to-face interviews with 600 black elderly people residing in the community. the sample had more females (70 percent) than males ... | 2008 | 2276687 |
| in vitro diffusion of lidocaine across endotracheal tube cuffs. | smooth emergence from general endotracheal anesthesia is frequently complicated by coughing induced by stimulation from an endotracheal tube. lidocaine and other local anesthetics have been shown to anesthetize important rapidly adpating stretch receptors in the dog trachea. with the aim of providing a reservoir for continuous lidocaine release to adjacent tracheal tissue, we examined the ability of clinically used concentrations of lidocaine to diffuse across a commonly used endotracheal tube c ... | 1990 | 2275911 |
| in vitro diffusion of lidocaine across endotracheal tube cuffs. | smooth emergence from general endotracheal anesthesia is frequently complicated by coughing induced by stimulation from an endotracheal tube. lidocaine and other local anesthetics have been shown to anesthetize important rapidly adpating stretch receptors in the dog trachea. with the aim of providing a reservoir for continuous lidocaine release to adjacent tracheal tissue, we examined the ability of clinically used concentrations of lidocaine to diffuse across a commonly used endotracheal tube c ... | 1990 | 2275911 |
| the effects of mandatory seat belt legislation on self-reported seat belt use among male and female college students. | the effect of seat belt legislation on self-reported seat belt use among male and female college students was investigated. questionnaires inquiring about seat belt use were administered to college students on three separate occasions: (i) two months prior to the time a mandatory seat belt law went into effect, (ii) two months after the law went into effect, and (iii) 16 months after the law went into effect. reported seat belt use increased significantly for male and female college students two ... | 2008 | 2275737 |
| comment: i.v. alcohol in prevention of delirium tremens. | 2008 | 2275246 | |
| interspecies scaling and comparisons in drug development and toxicokinetics. | 1. methods of interspecies extrapolation using physiological models and allometric scaling have been reviewed with their possible application to drug development, both for candidate drug selection and the interpretation of toxicokinetic data. 2. physiological models offer a mechanistic approach to extrapolation from one species to another, examining individual components which interrelate to produce the characteristics of the whole system. tissues of interest are arranged in anatomical order bas ... | 2008 | 2275215 |
| [thrombocyte aggregation and serum thromboxane in patients with acute myocardial infarction]. | treatment with acetylsalicylic acid reduces the mortality following acute myocardial infarction (ami). the mode of action is unknown but studies of patients with unstable angina pectoris have revealed that acetylsalicylic acid inhibits the platelet aggregating and vessel-constricting metabolite thromboxane b2. in the present investigation, we have examined ten patients with ami. platelet aggregation induced by arachidonic acid and serum thromboxane b2 were compared with findings in patients with ... | 2008 | 2275044 |
| [the structure-function relationships in alpha-interferons. a study of the antiviral activity of mutant forms of human alpha 2-interferon]. | 1990 | 2272281 | |
| platinum compounds with estrogen receptor affinity. | 1990 | 2272037 | |
| heterogeneous initiation due to slippage at the bacteriophage 82 late gene promoter in vitro. | rnas synthesized in vitro by purified escherichia coli rna polymerase from a bacteriophage 82 promoter are heterogeneous at the 5' end. we show that this heterogeneity results from variable addition of extra adenine residues, allowed by slippage of the initial oligonucleotide pppaaa-oh against its dna template sequence ttt. slippage backward by one base allows another a to be added, giving pppaaaa-oh, and this cycle can continue more than 20 times before it is ended by incorporation of ump encod ... | 1990 | 2271677 |
| resistance to receptor-mediated degradation of a murine epidermal growth factor analogue (egf-val-47) potentiates its mitogenic activity. | in most cell types two classes of epidermal growth factor (egf) receptors can be found: a major class that binds egf with relatively low affinity and a minor class that binds with very high affinity. structure-function studies have shown that mutations at amino acid 47 in the egf molecule severely reduce its affinity for the egf receptor but do not cause preferential binding to one or the other subclass of receptors. using three egf derivatives with a mutation at amino acid 47 (ser-47, leu-37-ty ... | 1996 | 2271672 |
| ribosomal protein l35: identification in spinach chloroplasts and isolation of a cdna clone encoding its cytoplasmic precursor. | we describe the isolation of spinach chloroplast ribosomal protein l35 and characterization of a cdna clone encoding its cytoplasmic precursor. this protein was only recently identified in ribosomes, but the sequences of four l35 genes have now been reported and confirm its presence in eubacteria, chloroplasts, and cyanelles. using n-terminal sequence data, oligonucleotides were designed and a cdna library was screened. the nucleotide sequence of the cdna clones shows that the spinach l35 protei ... | 1990 | 2271612 |
| synthetic peptide model of an essential region of an aminoacyl-trna synthetase. | a 40 amino acid sequence of the unsolved structure of escherichia coli alanine-trna synthetase is essential for trna binding and encodes an immunological determinant that cross-reacts with antibodies raised against a eukaryote (insect bombyx mori) alanine enzyme. the secondary structure of this sequence is predicted to be an amphiphilic alpha-helix that includes one aspartyl and eight glutamyl side chain carboxyl groups. the antibody reactivity and the conformation of a synthetic peptide model o ... | 1990 | 2271589 |
| phosphorescence and optically detected magnetic resonance studies of echinomycin-dna complexes. | echinomycin complexes with polymeric dnas and model duplex oligonucleotides have been studied by low-temperature phosphorescence and optical detection of triplet-state magnetic resonance (odmr) spectroscopy, with the quinoxaline chromophores of the drug used as intrinsic probes. although not optically resolved, plots of odmr transition frequencies versus monitored wavelength revealed heterogeneity in the phosphorescence emission of echinomycin, which was ascribed to the presence of two distinct ... | 1990 | 2271577 |
| inhibition of chymotrypsin by peptidyl trifluoromethyl ketones: determinants of slow-binding kinetics. | a series of seven peptidyl trifluoromethyl ketone (tfk) inhibitors of chymotrypsin have been prepared which differ at the p1 and p2 subsites. inhibition equilibria and kinetics of association and dissociation with chymotrypsin have been measured. the association rate of ac-phe-cf3 was measured at enzyme concentrations between 8 nm and 117 microm in order to examine the relation between the ketone/hydrate equilibrium of trifluoromethyl ketones and the "slow binding" by these inhibitors. the assoc ... | 1994 | 2271521 |
| defect in the integrity of an epidural catheter. | 1994 | 2271476 | |
| ultrasonic foetal head circumference as a means of assessing gestational age in nigerians. | in a cross-sectional study, we have established the foetal head circumference in pregnant nigerian women between the 16th to the 40th weeks of gestation. the relationship between the head circumference and gestational age is linear although there is some slight slowing of the growth rate after 32 weeks. a linear mathematical model was shown to describe the relationship between gestational age and head circumference and with the knowledge of one the other could be determined. the values obtained ... | 1996 | 2271418 |
| time of occurrence, duration, and ventricular rate of paroxysmal atrial fibrillation: the effect of digoxin. | 1995 | 2271354 | |
| acute pulmonary oedema on the ruwenzori mountain range. | a 40 year old man had an episode of severe pulmonary oedema at 4000-5000 m during the ascent of the margherita peak (5109 m) of mount stanley on the ruwenzori. he had taken acetazolamide and high dose dexamethasone to treat symptoms of acute mountain sickness. six years before he had been studied by right heart catheterisation as a healthy volunteer during hypoxic breathing at sea level. his pulmonary vascular reactivity had been within the normal range for 32 healthy subjects. this man had high ... | 1990 | 2271350 |
| [university news from tromsø. full degree study in nursing science]. | 1995 | 2271332 | |
| marrying age and services. | 1990 | 2271133 | |
| [from the parenchyma to the mucosa biopsy: significance and importance of local assays of antibiotics. a critical study]. | the authors discussed the relevance of antibiotic concentrations as measured in tissues and fluids of the respiratory tract. they analysed theoretical factors which influence tissue distribution of antibiotics as well as the results of studies carried out in animal and in human tissues. various factors may interfere with the results of antibiotic assays: but the data published by various groups were usually convergent: this confirms the significance of "tissue pharmacokinetics". new protocols ba ... | 1990 | 2270342 |
| stress, locus of control, social support, and psychological symptoms among head nurses. | this study was conducted to evaluate the relationships among work stress, nonwork stress, locus of control, social support, and head nurses' psychological symptoms. data were collected from head nurses (n = 300) representing all army hospitals in the united states; 21% of the volunteer sample were men. the results supported the hypotheses that perceived stress from both work and nonwork sources was positively related to psychological symptoms. direct effects for both internal locus of control an ... | 2008 | 2270304 |
| survey of enteropathogenic agents in children with and without diarrhoea in ghana. | a survey was carried out over 1 year in a rural area of ghana on the isolation, detection and/or identification of enteric pathogens from children under 5 years of age with and without diarrhoea. the isolation and detection rate of shigella flexneri, shigella dysenteriae, giardia lamblia and rotavirus were higher in children with diarrhoea than in controls. yersinia enterocolitica, vibrio cholerae and vibrio parahaemolyticus were not isolated during the period of this survey. the incidence of ot ... | 1990 | 2270006 |
| clearance of ceftriaxone in critical care patients with acute renal failure. | serum concentrations of ceftriaxone (rocephintm), a third generation cephalosporin, were monitored in 5 operative intensive care patients suffering from acute renal failure (arf) and compared to those of 7 patients without renal disturbance. for a period of 7 days, a fixed dose of 2 g/day was given by a 15 min infusion. pharmacokinetic parameters were calculated by fitting all serum and urine data measured over the period of treatment. ceftriaxone free fraction was measured on days 2 and 7. ther ... | 2007 | 2269714 |
| ontogeny of selective attention effects on event-related potentials in attention-deficit hyperactivity disorder and normal boys. | a longitudinal study of young attention-deficit hyperactivity disorder (adhd) boys has found clear evidence for developmental abnormalities in event-related potential (erp) waves that reflect cognitive processes associated with selective attentional tasks. boys alternated attention to auditory or visual modalities in a train of stimuli, in an attempt to detect target stimuli in the attended modality. results suggest that adhd boys' attentional difficulties are due to insufficient facilitation of ... | 2008 | 2268691 |
| false-positive diagnosis of adrenal phaeochromocytoma on metaiodobenzylguanidine (mibg) [correction of migb] scan. | 2007 | 2268520 | |
| false-positive diagnosis of adrenal phaeochromocytoma on metaiodobenzylguanidine (mibg) [correction of migb] scan. | 2007 | 2268520 | |
| comparison of oral erythromycin ethylsuccinate and ciprofloxacin in the treatment of acute respiratory tract infections. | a total of 619 patients with acute upper or lower respiratory tract infection were randomised to receive either erythromycin ethylsuccinate tablets at a dose of 1 g twice daily, or ciprofloxacin tablets 500 mg twice daily in a single-blind, multicentre study. the efficacy of each antibacterial was similar, with close to 90% of patients on each treatment being reported as either cured or improved. gastrointestinal symptoms were the most commonly reported side-effects, being similar in overall inc ... | 2008 | 2268518 |
| characterization of high molecular weight glycosylated forms of murine tumor necrosis factor. | tumor necrosis factor (tnf) is synthesized as a prohormone with an unusually long and atypical signal sequence which is absent from the mature secreted cytokine. in addition to mature 17 kda tnf, lps-stimulated murine macrophages secrete at least seven tnf-like proteins (isoforms) of differing electrophoretic mobility which appear as a "ladder" on sds-page. we here present data indicating that these isoforms derive not from sequential clipping of propiece fragments, but rather from differential ... | 2008 | 2268312 |
| human brain n-chimaerin cdna encodes a novel phorbol ester receptor. | a human brain-specific cdna encoding n-chimaerin, a protein of predicted molecular mass 34 kda, has sequence identity with two different proteins: protein kinase c (pkc) at the n-terminus and bcr protein [product of the breakpoint-cluster-region (bcr) gene, involved in philadelphia chromosome translocation] at the c-terminus [hall, monfries, smith, lim, kozma, ahmed, vannaisungham, leung & lim (1990) j. mol. biol. 211, 11-16]. the sequence identity of n-chimaerin with pkc includes the cysteine-r ... | 1990 | 2268301 |
| fate of injected glucagon taken up by rat liver in vivo. degradation of internalized ligand in the endosomal compartment. | the uptake and processing of glucagon into liver endosomes were studied in vivo by subcellular fractionation. after injection of [[125i]iodo-tyr10]glucagon and [[125i]iodo-tyr13]glucagon to rats, the uptake of radioactivity into the liver was maximum at 2 min (6% of the dose/g of tissue). on differential centrifugation, the radioactivity in the homogenate was recovered mainly in the nuclear (n), microsomal (p) and supernatant (s) fractions, with maxima at 5, 10 and 40 min, respectively; recovery ... | 1990 | 2268296 |
| alcuronium requirement in patients receiving phenytoin--a case report. | 2007 | 2268014 | |
| [school and occupational achievement of children and adolescents with epilepsy]. | 2008 | 2267818 | |
| pneumocystis carinii pneumonia in danish piglets. | 1990 | 2267715 | |
| spontaneous primary astrocytoma in the spinal cord of a mouse and a rat. | a spontaneous astrocytoma was observed as an incidental finding in the thoracic spinal cord of a control charles rivers cd-1 female mouse from a 2 yr oncogenicity study. an astrocytoma was also observed in the lumbar spinal cord of a charles rivers sprague-dawley control, female rat from a 2 yr oncogenicity study. the mouse was clinically normal and was sacrificed at the end of the 2 yr study. the rat was killed at 512 days of age because of posterior paralysis. | 1990 | 2267503 |
| [membranous glomerulonephritis. experience at the instituto nacional de la nutrición salvador zubirán]. | the purpose of this retrospective study was to study the incidence of idiopathic and secondary forms of membranous nephropathy in our institution, its clinical course and progression to chronic renal failure, and the risk factors associated with it. two hundred fourteen (16%) of the 1,287 renal biopsies obtained between 1962 and 1988 were primary glomerular diseases and 28 of this 214 (13%) were idiopathic membranous nephropathy. on the other hand 59 of 1,287 biopsies were membranous nephropathy ... | 2007 | 2267443 |
| an animal model of motor neuron disease in guinea pigs. | 1990 | 2267309 | |
| [cardiac findings in alcoholic liver disease]. | in a prospective study 53 patients with alcohol-induced liver disease (fatty liver in 27, cirrhosis in 26) were studied clinically and with non-invasive techniques (electrocardiogram, systolic time intervals, m-mode echocardiography, upright bicycle stress test) to detect a possible cardiac involvement. mean daily alcohol consumption was comparable in both groups (136 g/day over 16 years vs 124 g/day over 14 years). 15 to 41% of patients (more patients with fatty liver) complaint of angina pecto ... | 2008 | 2266911 |
| increased toxin production by vibrio cholerae o1 during survival with a green alga, rhizoclonium fontanum, in an artificial aquatic environment. | in the aquatic environment, the physiological state of vibrio cholerae can be affected by various environmental conditions (e.g., sunlight, ph, temperature, competition with other bacteria for nutrients, etc.). the effect of these factors on the toxigenicity of v. cholerae was investigated. toxin production by 5 toxigenic strains of v. cholerae incubated in laboratory microcosms containing rhizoclonium fontanum was tested at different time intervals. the microcosms were exposed to sunlight, and ... | 1990 | 2266879 |
| [experience in organizing medical care for the victims of the accident at the chernobyl atomic electric power station at a specialized hospital]. | organization of health care for victims of radiation accidents requires well-adjusted organizational activities, including an inpatient clinic with well-equipped reception, dosimetric, karyological and bacteriological laboratories, an intensive care department, a surgical (burn) department, a blood transfusion laboratory and equipment for plasmapheresis and hemosorption. therapy of such patients should be developed along the following lines: 1) prevention and therapy of infectious complications: ... | 2008 | 2266831 |
| hepatic antipyrine metabolism in athletes. | the aim of the present study was to investigate the influence of prolonged physical exercise on hepatic metabolism. an oral antipyrine loading test (15 mg/kg body weight) was carried out on 24 healthy male subjects: 8 controls, 8 sprinters (anaerobic activity), 8 long distance runners (aerobic activity). antipyrine clearance resulted to be significantly higher in athletes vs. controls, without a significant difference between the two groups of athletes. these results put forward the importance o ... | 2008 | 2266756 |
| effects of dialysis membranes on beta 2-microglobulin production and cellular expression. | we investigated the effects of different dialysis membranes on the production of beta 2-microglobulin (beta 2m) in peripheral blood mononuclear cell cultures (pbmnc) obtained from hemodialysis patients in a prospective cross-over design study. chronic dialysis with cuprophane membrane leads to an increase in beta 2m production from 129 +/- 11 ng/ml to 192 +/- 23 ng/ml (p less than 0.002). this increase is reversed by the use of a non-complement activating membrane polymethylmethacrylate. in addi ... | 2007 | 2266681 |
| effects of dialysis membranes on beta 2-microglobulin production and cellular expression. | we investigated the effects of different dialysis membranes on the production of beta 2-microglobulin (beta 2m) in peripheral blood mononuclear cell cultures (pbmnc) obtained from hemodialysis patients in a prospective cross-over design study. chronic dialysis with cuprophane membrane leads to an increase in beta 2m production from 129 +/- 11 ng/ml to 192 +/- 23 ng/ml (p less than 0.002). this increase is reversed by the use of a non-complement activating membrane polymethylmethacrylate. in addi ... | 2007 | 2266681 |
| nonagglutinable vibrio cholerae septicaemia. | 1990 | 2266091 | |
| the use of adrenal substance in the treatment of asthma. 1900. | 2007 | 2266071 | |
| the use of adrenal substance in the treatment of asthma. 1900. | 2007 | 2266071 | |
| selective inhibition of growing pigment epithelial cells by a receptor-directed immunotoxin. | an immunotoxin conjugate of a murine monoclonal antibody against human transferrin receptors and the a chain of ricin was examined for its potential to inhibit selectively the growth of retinal pigment epithelial (rpe) cells which grow in an uncontrolled manner in proliferative vitreoretinopathy. the probable efficacy of such an agent in vivo stems from the observation that actively proliferating cells possess many more transferrin receptors than normal quiescent cells. the authors showed in vit ... | 1990 | 2265991 |
| the molecular mode of brain mrna processing damage followed by the suppression of post-transcriptional poly(a) synthesis with cordycepin. | complete suppression of polyadenylation of nuclear precursors of rat brain mrna by cordycepin leads to degradation of some translatable sequences of both poly(a)(+)- and poly(a)- pre-mrna localized in 80s hnrnp-particles. this fact has been established by comparative analysis of the data of two-dimensional gel-electrophoretic mapping of translation products synthesized in reticulocytic cell-free system using the exogenous purified templates of rapidly labelling translatable 9-17s hn rna (pre-mrn ... | 1990 | 2265908 |
| age distribution of erythrocyte population in late pregnancy. | the age population distribution of erythrocytes in late pregnancy was evaluated by the volume and density distribution of cells. this approach enables an evaluation of the life span of erythrocytes in the circulation without using radioactive elements. a younger cell population was found in the circulation of women in late pregnancy as compared to nonpregnant women of similar ages, which might be indicative of shortened life span of erythrocytes. this shortened life span might be explained by th ... | 2008 | 2265799 |
| kinetic study of esterification by immobilized lipase in n-hexane. | the kinetic of the esterification of oleic acid by ethanol catalyzed by immobilized lipase of mucor miehei in n-hexane as a solvent has been completely studied. the kinetics of the reaction are suggested to agree with a ping-pong bi bi mechanism in which only inhibition by excess of ethanol has been identified. values of all apparent kinetic parameters were computed. no evidence of any significant external diffusional limitation which could account for these values has been detected. optimizatio ... | 1990 | 2265698 |
| a new sensitive fluorometric assay for the metabolism of (--)-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by human hair follicles. | a new sensitive fluorometric assay was established to measure the stereospecific formation of benzo[alpha]pyrene tetrols formed after cytochrome p450-dependent metabolism of (--)-7,8-dihydroxy-7,8- dihydrobenzo[a]pyrene by human hair follicles. this simple assay requires three human hair follicles and a low (0.5-2.0 microm) substrate concentration and has a limit of detection of approximately 0.3 fmol of tetrols. freshly isolated human hair follicles from 20 adult volunteers (10 non-smokers and ... | 1990 | 2265467 |
| [a training program after coronary surgery improves blood lipid profile]. | 2008 | 2263103 | |
| [microbiological assay method of bmy-28100 and some other cephem antibiotic in serum and tissues. development of new sample preparation with evan's blue, a high albumin binding dye]. | with a new simple sample pretreatment, microbiological assay methods for quantitative determination of bmy-28100 and some other cephem antibiotics in serum and tissues have been developed. presented sample pretreatment was founded on the extraction with evans' blue, a high serum protein binding dye, and the ultrafiltration using cellulose membrane (millipore; mw cutoff is 10,000) to which evans' blue was specifically absorbed. regardless of sample media, antibiotic contents in filtrates were det ... | 1990 | 2262961 |
| glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: the protective effect of allopurinol. | acetaminophen (500 mg/kg i.p.) induced hepatotoxicity in fasted icr mice in vivo. acetaminophen also caused a long-lasting 50% reduction of the hepatic atp content, an irreversible loss of hepatic xanthine dehydrogenase activity and a transient increase of the xanthine oxidase activity. all effects occurred before parenchymal cell damage, i.e., the release of cellular enzymes. the hepatic content of gsh and gssg was initially depleted by acetaminophen without affecting the gssg:gsh ratio (1:200) ... | 2007 | 2262912 |
| two autosomal trisomies in the horse: 64,xx,-26,+t(26q26q) and 65,xx,+30. | the phenotypic effects in a yearling arab filly of a newly described equine autosomal trisomy syndrome for chromosome 30 (65,xx,+30) consisted of small size and severe angular deviation of front legs accompanied by mild polydactyly, but no mental dullness. this case was associated with advanced maternal age. additional banding studies of a second trisomy case confirmed the assignment to chromosome 26 (64,xx,-26,+t(26q26q)) and evidence of her fertility was presented. | 1990 | 2262139 |
| asymmetric brain stem auditory evoked responses in infants treated with extracorporeal membrane oxygenation. | brain stem auditory evoked responses (baers) were obtained in 25 infants who received extracorporeal membrane oxygenation (ecmo) for severe respiratory failure. tracings were obtained by means of a nicolet ca-2000 averager, using a conventional paradigm. the presence or absence of replicated responses at 35 and 75 db nhl were recorded for each ear. interpeak latencies i-iii, iii-v, and i-v were measured and differences between right and left ears were compared, using a matched pair t-test. wave ... | 2008 | 2262085 |
| polyamine metabolism and uptake during phaseolus vulgaris lectin, pha-induced growth of rat small intestine. | kidney bean lectin, pha, stimulated the hyperplastic and hypertrophic growth of rat small intestine. this growth was preceded by a rapid accumulation of polyamines in the small intestine. however, since the lectin had little effect on in situ polyamine biosynthesis, most of the polyamines must have been of extracellular origin. to investigate the source of polyamines, both the luminal uptake and basolateral transport of polyamines by the rat small intestine were measured in vivo. luminal polyami ... | 1990 | 2262068 |
| survival of toxigenic vibrio cholerae o1 with a common duckweed, lemna minor, in artificial aquatic ecosystems. | cholera epidemics occur twice a year in bangladesh. during epidemics, vibrio cholerae o1 are isolated from patients, as well as from the surface water, but the bacteria disappear during inter-epidemic periods. their reservoirs or sites of survival and multiplication during inter-epidemic period are still unknown. the present survival study in the laboratory explored the role of an aquatic plant, lemna minor (duckweed), as a possible reservoir. l. minor was added to sea-salt solution at ph 8.5, c ... | 1990 | 2260179 |
| [organ injuries during gastrectomy in peptic ulcer]. | 2008 | 2259107 | |
| stimulus train-induced bursting in hippocampal slices: difference between ca1 and ca2/3 subfields. | we studied the relationship between ca2/3 and ca1 subfields in the generation of stimulus train-induced bursting using in vitro hippocampal slices. repeated stimulation to the stratum radiatum induced three types of epileptiform activities: afterdischarge bursts, spontaneous bursts and single stimulus-triggered bursts. in the intact slices, spontaneous bursts in ca3 preceded those in ca1, whereas afterdischarge bursts in ca3 followed those in ca1 when it was possible to distinguish differences i ... | 1990 | 2259016 |
| synthesis and cytotoxicity studies of 8-amino-6-methyl-2-beta-d-ribofuranosyl-1,2,3,5,6,7-hexaazaacenaphthyle ne (7-aza-tcn) and the corresponding 2'-deoxy- and arabinonucleoside analogues. | the tricyclic nucleoside 8-amino-6-n-methyl-2-beta-d-ribofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene was synthesized from 8-amino-6-n-methyl-4-(methylthio)-2-beta-d-ribofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene. the 2'-deoxy analogue of 5, 8-amino-6-n-methyl-2-(2-deoxy-beta-d-ribofuranosyl)-1,2,3,5,6, 7-hexaazaacenaphthylene (11), and the arabino analogue of (5), 8-amino-6-n-methyl-2-beta-d-arabinofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene (14) were synthesized from 5. nucleosides 2,3,4,5, ... | 2007 | 2258902 |
| synthesis and cytotoxicity studies of 8-amino-6-methyl-2-beta-d-ribofuranosyl-1,2,3,5,6,7-hexaazaacenaphthyle ne (7-aza-tcn) and the corresponding 2'-deoxy- and arabinonucleoside analogues. | the tricyclic nucleoside 8-amino-6-n-methyl-2-beta-d-ribofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene was synthesized from 8-amino-6-n-methyl-4-(methylthio)-2-beta-d-ribofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene. the 2'-deoxy analogue of 5, 8-amino-6-n-methyl-2-(2-deoxy-beta-d-ribofuranosyl)-1,2,3,5,6, 7-hexaazaacenaphthylene (11), and the arabino analogue of (5), 8-amino-6-n-methyl-2-beta-d-arabinofuranosyl-1,2,3,5,6, 7-hexaazaacenaphthylene (14) were synthesized from 5. nucleosides 2,3,4,5, ... | 2007 | 2258902 |
| the differential efficacy of antihypertensive agents in the elderly. | a number of controlled trials have shown that antihypertensive therapy is beneficial to the elderly (greater than or equal to 60 years of age). even so, there may be deleterious age-related effects associated with such therapy. because of physiological and pathophysiological problems peculiar to the elderly (many of which remain to be defined precisely), both benefits and untoward effects of antihypertensive drugs differ, sometimes within classes of agents themselves. none of the traditional age ... | 2008 | 2258887 |
| differences in blood pressure profile between young and elderly hypertensive patients. | we studied 40 subjects, 20 under 60 yrs old (10 normotensive and 10 hypertensive) and 20 over 60 yrs old (10 normotensive and 10 hypertensive). each patient underwent a 24-hour ambulatory blood pressure monitoring (8:00 a.m. to 8:00 a.m.), by a noninvasive method using an icr 5300 apparatus. systolic blood pressure was significantly higher on random measurement and during the daytime in the older patients. although comparison of the other parameters did not reveal significant differences, we not ... | 2008 | 2258885 |
| hypertension control and management in slovenia, yugoslavia. | data were collected from 413 questionnaires sent to general practitioners throughout slovenia, accounting for half the physicians in this discipline. bp was measured most commonly in the sitting position (72%), mostly on the left arm. most respondents (93%) used only one cuff size. correction of bp readings according to the patient's arm circumference was used by 63% of the respondents. seventy-eight percent of the general practitioners recorded phase v of the korotkoff sounds for diastolic bp. ... | 2008 | 2258857 |
| are more consultants needed for dermatology? | 2008 | 2258854 | |
| interfaces in medicine: asthma. report of a conference. | 2007 | 2258849 | |
| interfaces in medicine: asthma. report of a conference. | 2007 | 2258849 | |
| mediator and cellular mechanisms in asthma. the philip ellman lecture 1990. | 2007 | 2258848 | |
| mediator and cellular mechanisms in asthma. the philip ellman lecture 1990. | 2007 | 2258848 | |
| the use of radiotelemetry after discharge from the coronary care unit. | forty-six of 110 consecutive admissions to the coronary care unit (ccu) were monitored by telemetry after discharge from the unit. one of three patients with sudden cardiac death was resuscitated successfully and four patients developed atrial fibrillation which resulted in investigation by echocardiography and treatment with anticoagulants. significant ventricular ectopic activity was detected in four other patients. arbitrary selection of patients resulted in those with complicated courses in ... | 2008 | 2258842 |
| [clinical, bacteriological, and immunological examination and treatment of two papillon-lefevre syndrome patients]. | papillon-lefèvre syndrome (pls) is a rare disease accompanied by palmo-plantar hyperkeratosis and rapidly progressive periodontal breakdown of deciduous and permanent dentition. two unrelated female pls patients, four and seven years old, with severe periodontal destruction were examined. antibody titers against seven strains by the enzyme-linked immunosorbent assay (elisa), microbial cultures from deep periodontal pockets and mouth rinse samples and immunoblotting analysis were performed. titer ... | 1990 | 2258685 |
| [clinical, bacteriological, and immunological examination and treatment of two papillon-lefevre syndrome patients]. | papillon-lefèvre syndrome (pls) is a rare disease accompanied by palmo-plantar hyperkeratosis and rapidly progressive periodontal breakdown of deciduous and permanent dentition. two unrelated female pls patients, four and seven years old, with severe periodontal destruction were examined. antibody titers against seven strains by the enzyme-linked immunosorbent assay (elisa), microbial cultures from deep periodontal pockets and mouth rinse samples and immunoblotting analysis were performed. titer ... | 1990 | 2258685 |
| [fabrication and mechanical properties of sintered hydroxyapatite]. | 2007 | 2258680 | |
| [fabrication and mechanical properties of sintered hydroxyapatite]. | 2007 | 2258680 | |
| [early and long-term results of percutaneous transluminal coronary angioplasty in angina pectoris]. | 2007 | 2258666 | |
| [early and long-term results of percutaneous transluminal coronary angioplasty in angina pectoris]. | 2007 | 2258666 | |
| [anti-dna antibody, anti-idiotypic antibody and systemic lupus erythematosus]. | 2007 | 2258660 | |
| [anti-dna antibody, anti-idiotypic antibody and systemic lupus erythematosus]. | 2007 | 2258660 | |
| [development and testing of cholera enterotoxin gene probe for detection of toxigenic vibrio cholerae o1]. | a dna probe was developed for the genetic detection from cholera enterotoxin (ct) producing vibrio cholerae o1 and other organisms. the structural genes of ct (ctx) were cloned from chromosomal dna of ct producing v. cholerae o1 569b. we subcloned a 552-base-pair fragment encoding a part of ct a-subunit for use of the ct-probe, and made the recombinant plasmid called pskm24 which has eight copies of the ct-probe. the 32p-labeled ct-probe detected ctx in 72 isolates such as v. cholerae o1, v. cho ... | 1990 | 2258649 |
| [detection of toxigenic vibrio cholerae o1 using polymerase chain reaction for amplifying the cholera enterotoxin gene]. | a rapid and simple procedure using polymerase chain reaction (pcr) was developed for the detection of cholera enterotoxin (ct) producing character. this method is based on amplifying a 380 base pair (bp) segment of the ct gene (ctx) which controls the production of ct. two single-stranded oligonucleotides, synthetized to be complementary to the known nucleotide sequences of genes encoding the a-subunit of ctx, were used as extension primers. the oligonucleotide sequences are 5'tcaaactatattgtctgg ... | 1990 | 2258648 |
| non-aids-associated kaposi's sarcoma (classical and endemic african types): treatment with low doses of recombinant interferon-alpha. | in the treatment of the classical and endemic african forms of kaposi's sarcoma (ks), radiation therapy and chemotherapy have been widely used with varying degrees of success and morbidity. we here report our preliminary experiences with low doses of recombinant interferon alfa-2b (rifn alpha-2b) in the treatment of these types of ks, non-linked to the acquired immunodeficiency syndrome (aids). ten consecutive patients (eight patients with classical and two with endemic ks) with a median age of ... | 2008 | 2258634 |
| staphylococcus aureus infection of human endothelial cells potentiates fc receptor expression. | vasculitis, a recognized complication of staphylococcal-endovascular infections, may result in part, from the expression of fcr by staphylococcus aureus-infected endothelial cells. fcr were measured using [51]cr labeled srbc preincubated with rabbit anti-srbc igg. fcr were not detected on uninfected endothelial cells, but were demonstrated on s. aureus infected cells using igg, but not igm labeled srbc. fcr expression was dependent on the initial bacterial density (greater than or equal to 8 x 1 ... | 1990 | 2258617 |
| a reappraisal of the role of methimazole and other factors on the efficacy and outcome of radioiodine therapy of graves' hyperthyroidism. | the outcome of radioiodine therapy of graves' hyperthyroidism was retrospectively evaluated in 274 consecutive patients treated from 1975 to 1984. at 1-yr follow-up, permanent hypothyroidism occurred in 36.9% of patients and the cumulative incidence of hypothyroidism progressively increased up to 79.3% after 7-10 yr. at the end of the follow-up period, 148 patients (54%) were hypothyroid, 115 (42%) euthyroid and 11 (4%) still hyperthyroid. the prevalence of hypothyroidism was significantly highe ... | 1990 | 2258580 |
| a reappraisal of the role of methimazole and other factors on the efficacy and outcome of radioiodine therapy of graves' hyperthyroidism. | the outcome of radioiodine therapy of graves' hyperthyroidism was retrospectively evaluated in 274 consecutive patients treated from 1975 to 1984. at 1-yr follow-up, permanent hypothyroidism occurred in 36.9% of patients and the cumulative incidence of hypothyroidism progressively increased up to 79.3% after 7-10 yr. at the end of the follow-up period, 148 patients (54%) were hypothyroid, 115 (42%) euthyroid and 11 (4%) still hyperthyroid. the prevalence of hypothyroidism was significantly highe ... | 1990 | 2258580 |
| [tachistoscopy: an experimental method for studying cerebral hemispheric specialization]. | tachistoscopy is an experimental method used to study processes involved in hemispheric specialisation and the lateralisation of cerebral functions. the authors review the various findings emerging from this technique and briefly assess its methodological constraints. | 2007 | 2258554 |
| [neuro-anatomy of retinoblastoma]. | in four cases of retinoblastoma examined with the method of golgi we have only found vessels and glial elements at different stages of differentiation. moreover, in the areas containing typical rosettes, golgi method revealed some isolately impregnated elements resembling photoreceptors in evolution. within the retina abuting on the tumor were found only normal retinal nervous elements. some nervous elements were found also in areas where the tumor tissue intermingled with infiltrated neighbouri ... | 2008 | 2258552 |
| [indications and advantages of gingival flange in fixed prosthetics. a new technique]. | 2006 | 2258229 | |
| a comparative clinical trial of duodenal ulcer healing with two regimens of cimetidine: 800 mg once nightly and 400 mg twice daily. | the efficacy and safety of two dosage regimens of cimetidine were compared in a single-blind study of 50 adults with endoscopically proven duodenal ulcers. patients were randomly allocated to receive 800 mg cimetidine taken once nightly or 400 mg cimetidine taken twice daily for 4 weeks. following 4 weeks' treatment patients again underwent endoscopy and, if healing was incomplete, they received a further 4 weeks' treatment. at 4 weeks, healing occurred in 21/25 (84%) patients on the once-daily ... | 2008 | 2257964 |
| [regulation of peptide hydrolase activity in psoriasis]. | clinico-biological examination of 154 patients with psoriasis resulted in data showing high activity of endo- and exopeptidases in efflorescences of that dermatosis. this was accompanied by depressed activity of trypsin inhibitor. at the same time magnesium deficiency, polysaccharide decrease and leucocyte increase were stated to be in the focus of skin damage. that character of interrelation, which play an important role in the pathogenesis of this widespread skin disease, is demonstrated. | 2008 | 2257941 |
| tgf-alpha and tgf-beta expression during sodium-n-butyrate-induced differentiation of human keratinocytes: evidence for subpopulation-specific up-regulation of tgf-beta mrna in suprabasal cells. | sodium-n-butyrate (nab) induces terminal differentiation and cornified envelope formation in cultured human keratinocytes. in the present study we explored the question of whether nab-induced maturation could be mediated through changes in tgf-alpha and tgf-beta expression in normal keratinocytes. nab induced a four-fold increase in tgf-beta mrna transcript levels. this increase in tgf-beta mrna abundance occurred only within the nonbasal keratinocyte subpopulation which maximally responds to na ... | 1990 | 2257881 |
| tgf-alpha and tgf-beta expression during sodium-n-butyrate-induced differentiation of human keratinocytes: evidence for subpopulation-specific up-regulation of tgf-beta mrna in suprabasal cells. | sodium-n-butyrate (nab) induces terminal differentiation and cornified envelope formation in cultured human keratinocytes. in the present study we explored the question of whether nab-induced maturation could be mediated through changes in tgf-alpha and tgf-beta expression in normal keratinocytes. nab induced a four-fold increase in tgf-beta mrna transcript levels. this increase in tgf-beta mrna abundance occurred only within the nonbasal keratinocyte subpopulation which maximally responds to na ... | 1990 | 2257881 |
| mhc-restricted antibody responses to trichuris muris excretory/secretory (e/s) antigen. | two panels of h-2 recombinant mice were used in a detailed serological study to analyse the role of h-2-linked genes in the control of the antibody response to excretory/secretory (e/s) antigens of trichuris muris. an apparent h-2q (i-aq) restriction on the early development of high levels of igg1 antibody to e/s antigen was revealed by elisa. no such restriction was demonstrated for the specific igg2a response patterns. recognition of two high molecular weight antigens (90-95 kda, 105-110 kda) ... | 1990 | 2255562 |
| in vitro and in vivo anticancer activity of mitozolomide and sparsomycin in human tumor xenografts, murine tumors and human bone marrow. | the colony formation in agar of human tumor xenografts, of murine tumors and of human bone marrow was used as a test system to determine the in vitro activity of the two novel cytostatic agents, mitozolamide and sparsomycin. mitozolomide was additionally studied in vivo in nine human tumor xenografts. the comparison of in vitro/in vivo activity allows an assessment of the relevant in vitro dose based on in vivo pharmacological behavior of a compound. both compounds showed clear dose/response eff ... | 1990 | 2254373 |
| neuroendocrine measurements in steers grazed on endophyte-infected fescue. | dopamine (da), serotonin (5ht) and selected precursors and metabolites were measured in the anterior pituitary gland, hypothalamus and pineal gland, along with serum prolactin (prl) and average daily gains (adg), in steers (n = 6/group) grazing endophyte (acremonium coenophialum)-infected and noninfected fescue (festuca arundinacea schreb). paddocks (two/treatment) were designated 100f and 0f (100 and 0% infection, respectively). after 6 wk, three animals from one of the 100f paddocks were excha ... | 1990 | 2254203 |