Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| experimental colitis alters myenteric nerve function at inflamed and noninflamed sites in the rat. | studies in inflammatory bowel disease have shown extensive structural abnormalities in the enteric nervous system of inflamed and noninflamed gut; however, functional correlates are lacking. the aim of this study was to determine the effect of colitis on myenteric nerve function at inflamed and noninflamed sites in rat intestine. | 1995 | 7657099 |
| [epidemiology of trichinosis in chile. prevalence study by immunodiagnostic reactions]. | in the period 1983-1994 a series of seroepidemiological surveys, by using immunodiagnostic tests for trichinosis, was carried out in 138 localities and health institutions from the 13 regions of the country. thus, a total of 12,882 randomly selected persons, with different sex and age distribution, were submitted to precipitin test and indirect hemagglutination test for trichinosis. one hundred and ninety one (1.5%) persons resulted positive for trichinosis. higher rates of infection were observ ... | 1994 | 7654290 |
| [trichinosis outbreak in purranque county, x region, chile. october-november, 1992]. | an outbreak of trichinosis occurred in purranque county, x region, chile, between october and november of 1992, which involved 36 persons. the incubation period, determined by the clinical picture and laboratory assays, fluctuated between 10 and 12 days. myalgias (88.9%) and palpebral oedema (86.1%), were the most important symptoms, followed by fever (44.4%) and headache (33.3%). eosinophils count ranged from two to 42% the first week, and this value raised to 55% the second week of the outbrea ... | 1994 | 7632339 |
| a method for isolation and partial purification of trichinella spiralis nurse cells. | invasion of vertebrate muscle cells by larvae of trichinella spiralis is accompanied by redifferentiation of the host myofiber into a novel structure called the nurse cell. the nurse cell protects and nurtures the enclosed parasite during its long stay in host muscle. it is anatomically independent of the surrounding uninfected muscle cells and can be isolated from host tissue by mechanical or enzymatic means. current methods employed for this purpose have yielded only small numbers of nurse cel ... | 1995 | 7623214 |
| a study on patients with eosinophilia of suspected parasitic origin. | a study of 53 patients with eosinophilia of suspected parasitic origin was conducted. investigations done for each case included, stool and urine examinations, absolute eosinophilic count and countercurrent immunoelectrophoresis (ciep) using crude antigens of fasciola hepatica, schistosoma mansoni worms, trichinella spiralis and toxocara canis larvae, and hydatid fluid. stool examination revealed six cases with fasciola eggs, two with ascaris lumbricoides and one with s. mansoni eggs. the eosino ... | 1995 | 7602166 |
| short report: an outbreak of trichinosis in navarra, spain. | trichinosis is an infection contracted by ingestion of meat containing viable larvae of the nematode trichinella spiralis. this report concerns an outbreak of infections with this parasite in navarra, spain that was associated with home-prepared pork products. after the detection of a person with trichinosis, a study of all subjects that had ingested meat from the presumably infected pork was carried out. forty-four members of eight families were enrolled in the study. ten had symptoms suggestiv ... | 1995 | 7573704 |
| prevalence of igg antibodies to trichinella spiralis in dogs in macedonia, northern greece. | an enzyme-linked immunosorbent assay (elisa) was used to detect t. spiralis infection in dogs, using larval t. spiralis excretory-secretory (es) antigen. forty-three (4.3%) dog sera out of 1000 revealed the presence of igg t. spiralis. the positive sera were distributed in three groups; 21 (2.1%) weakly positive, 14 (1.4%) moderately positive, and eight (0.8%) strongly positive. | 1995 | 7571342 |
| antibody response to a protease secreted by trichinella spiralis muscle larvae. | in the present study we analyzed the humoral response of trichinella spiralis-infected mice to a 35-kda protease (purified from the excretory-secretory products of t. spiralis muscle larvae) by a western-blot procedure and an enzyme-linked immunosorbent assay (elisa) technique using a panel of postinfection mouse anti-trichinella sera. the results demonstrated that this response was time-dependent and that infected mice could be distinguished from controls. in addition, inhibition assays demonst ... | 1995 | 7567916 |
| suppression of transplant immunity in experimental trichinellosis. | skin allograft rejection in balb/c and c57bl/6j mice following experimental infection with 300 larvae of trichinella spiralis or trichinella pseudospiralis was studied. skin grafts from normal c57bl/6j mice were transplanted to infected balb/c mice and vice versa at days 3, 10, 20 and 30 post-infection. the clinical criteria for graft rejection, scarring and graft falling, were followed. the results indicated that t. spiralis and t. pseudospiralis infections induced a significant delay in graft ... | 1995 | 7554818 |
| progesterone modulation of anaphylactically induced ion transport in uterus and intestine. | the objective of this study was to investigate the role of progesterone in modulating electrophysiological responses to antigenic challenge that are reflective of immune functions in uterine and jejunal mucosae. in the rat-trichinella spiralis, host-parasite system, an enteric infection with a microscopic nematode sensitizes both the jejunum and uterus. electrophysiological correlates of local anaphylaxis or type i hypersensitivity were monitored in vitro throughout the estrus cycle and during p ... | 1995 | 7549500 |
| substance-p-mediated intestinal inflammation: inhibitory effects of cp 96,345 and sms 201-995. | the proinflammatory peptide substance p (sp) has been shown to be intimately involved in the local inflammatory processes of trichinella-spiralis-induced murine intestinal inflammation. significant increases in sp, increased myeloperoxidase levels coupled with local morphological deterioration of the jejunum and impaired lymphocyte responses to exogenous sp in vitro have been associated with the model. we have recently determined that the elimination of increased levels of sp via anti-sp antibod ... | 1994 | 7545531 |
| stem cell factor contributes to intestinal mucosal mast cell hyperplasia in rats infected with nippostrongylus brasiliensis or trichinella spiralis, but anti-stem cell factor treatment decreases parasite egg production during n brasiliensis infection. | we assessed the effects of the c-kit ligand, stem cell factor (scf), in the jejunal mucosal mast cell hyperplasia that occurs during infection with the intestinal nematodes, nippostrongylus brasiliensis or trichinella spiralis in rats. compared with vehicle-treated rats, rats treated with scf (25 micrograms/kg/d, intravenous [i.v.] for 14 days) during n brasiliensis infection exhibited significantly higher levels of the rat mucosal mast cell (mmc)-associated protease, rat mast cell protease ii ( ... | 1995 | 7544650 |
| altered neuropeptide content and cholinergic enzymatic activity in the inflamed guinea pig jejunum during parasitism. | we investigated the effects of an enteric infection with the parasitic nematode, trichinella spiralis, on peptidergic and cholinergic neural pathways of the guinea pig jejunum. the content of the enteric neuropeptides, substance p (sp) and vasoactive intestinal peptide (vip), and the activities of the key cholinergic enzymes, acetylcholinesterase (ache) and choline acetyltransferase (chat), were measured and compared in extracts of jejunal muscularis externa (me) obtained from uninfected jejunum ... | 1995 | 7541515 |
| molecular analysis of antigens targeted by protective antibodies in rapid expulsion of trichinella spiralis. | rapid expulsion is a protective immune mechanism which eliminates as much as 99% of a challenge infection of trichinella spiralis muscle larvae from the gastrointestinal tract of suckling rats. protective monoclonal antibodies (mabs) generated against larval excretory-secretory antigens (esa) specifically recognize a 45-kda glycoprotein, gp45, in addition to a distinct profile of other cross-reactive antigens that are also recognized by non-protective mabs. recent data indicate that protective m ... | 1994 | 7526209 |
| neuroimmune communication in the submucous plexus of guinea pig colon after infection with trichinella spiralis. | enteric neuroimmune communication in gastrointestinal hypersensitivity responses includes antigen detection by mast cells and release of chemical messages to the enteric nervous system. the aim of this study was to analyze the electrical and synaptic behavior of neurons in the colonic submucous plexus during exposure to trichinella spiralis antigen in animals infected earlier with the parasite. | 1994 | 7525397 |
| intestinal anaphylaxis: radiation-induced suppression. | the gastrointestinal tract is highly sensitive to ionizing radiation. some of the most radiosensitive cells in this system are mast cells and epithelium. this article describes experiments that test the hypothesis that irradiation suppresses mucosal immune responses in which mast cells and epithelium are involved. the hypothesis was tested by examining the impact of ionizing radiation on anaphylactically mediated cl- secretion in jejunum of rats sensitized by trichinella spiralis infection and c ... | 1994 | 7524351 |
| histochemical and morphological studies on trichinella spiralis larvae treated with high hydrostatic pressure. | histochemical and morphological observations were made on trichinella spiralis larvae treated with hydrostatic pressures of 100, 150, 200 and 300 mpa using hematoxylin-eosin (he), periodic acid-schiff (pas) and azan staining. few histochemical changes were observed in he and pas stained larvae after pressurization at 200 mpa and under. however, red staining by azan changed to blue in the anterior stichosome of larvae and skeletal muscle of mice, when the hydrostatic pressure was raised from 150 ... | 1994 | 7520888 |
| structural and molecular changes in intestinal smooth muscle induced by trichinella spiralis infection. | infection with trichinella spiralis in the rat causes altered intestinal motility and jejunal smooth muscle contractility by day 6 postinoculation. the purpose of this study was to determine structural and molecular changes in the smooth muscle that could account for the functional changes that have been reported. by day 6 postinoculation, there was an increase in thickness of both muscle layers of the jejunum. this increase in mass was accompanied by an increase in total protein content of the ... | 1994 | 7515575 |
| interleukin 1 beta-induced increase in substance p in rat myenteric plexus. | substance p (sp) is increased in the inflamed intestine of trichinella spiralis-infected rats, but the underlying mechanism is unknown. interleukin 1 beta (il-1 beta) messenger rna and protein is expressed in the longitudinal muscle-myenteric plexus (lm-mp) of this model. thus, the purpose of the study was to examine the ability of human recombinant il-1 beta (hril-1 beta) to increase sp in lm-mp preparations from the intestine of noninfected rats. | 1993 | 7504644 |
| patterns of cytokine mrna in trichinella spiralis infected rats. | 1995 | 7502935 | |
| [edema of the lower limbs revealing trichinosis identified by duodenal biopsy]. | 1995 | 7501630 | |
| [characterization of surface antigens of the nematode parasite trichinella spiralis: study of its role in protection mechanisms and their usefulness in the diagnosis of trichinosis]. | among the most important aspects in the study of trichinosis are the development of specific and sensitive diagnostic methods for the detection of the infection by the parasite as well as the characterization of antigens from trichinella spiralis that induce protection in the host. in the context, the characterization of surface stichosome and excretory secretory antigens of t. spiralis muscle larvae has been an important issue due to the high immunogenicity of such components in most hosts so f ... | 1995 | 7493736 |
| purification and preliminary characterization of a protease from the excretion-secretion products of trichinella spiralis muscle-stage larvae. | a protease from excretion-secretion products of trichinella spiralis muscle-stage larvae was purified by continuous elution electrophoresis. the state of purification was analyzed electrophoretically using one- and two-dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis. the purified enzyme was shown to be a single polypeptide with an estimated molecular mass of 35 kda and isoelectric point of 6.2. following purification, the enzyme activity was measured by hydrolysis of gelati ... | 1995 | 7483238 |
| [the synthesis and study of the acute toxicity and anthelmintic activity of new 2-methylthiobenzimidazoles]. | several derivatives of 2-methylthiobenzimidazoles were synthesized and assayed for anthelmintic activity. following these studies, 2-methylthio-5-(1-chloronaphthyloxy-2)-6-chlorobenzimidazole (g-1557) has been selected as a tichinellacide for detailed investigations. | 1995 | 7476681 |
| [the distribution of trichinella nativa, t. nelsoni and t. pseudospiralis in eurasia]. | a hundred and forty-six isolates of trichinella from various regions of eurasia have been identified by the crossbreeding method (1 male + 1 female). three independent species of trichinella: t. nativa, t. nelsoni, and t. pseudospiralis were found to parasite on the animals of this continent. the former two are dominant species of different territories. t. nativa occupies the whole continental zone to the north and the north-east of the isotherm minus 5-6 degrees c in january and t. nelsoni popu ... | 1995 | 7476675 |
| detection of trichinella spiralis muscle larvae in naturally infected horses. | human trichinellosis outbreaks related to horsemeat consumption have been reported in france and italy in recent years. in order to determine if trichinella is present in horses slaughtered at an abattoir in the state of mexico, diaphragm muscle tissue samples (22-37 g) from 80 horses were examined by artificial digestion. four of these samples had larvae that were characterized as trichinella sp. by morphological criteria and as trichinella spiralis by the polymerase chain reaction. | 1995 | 7472874 |
| effect of trichinella spiralis infection on the experimental amebic liver abscess in hamsters. | the development of experimental amebic liver abscess in hamsters was inhibited by a previous infection with the nematode parasite trichinella spiralis, such that liver abscesses were present in 26% of hamsters with t. spiralis infection and in 80% of t. spiralis-free controls. the protective effect of t. spiralis infection is believed to be exerted through a non-specific activation of cellular immunity, with macrophages as probable effector cells. | 1980 | 7469639 |
| [ultrastructural study of oogenesis in trichinella spiralis (author's transl)]. | the ultrastructural study of oogenesis in t. spiralis makes it possible to subdivide the oocytic growth into 2 phases: a first phase is characterized by an intense nucleolar activity and the transfer of nuclear material to the cytoplasm; a second phase during which the cytoplasmic mass increases and energy reserves (glycogen, lipids) appear. the oocyte does not contain any protein vitellus. | 1980 | 7469309 |
| the nonrandom, negative binomial distribution of experimental trichinellosis in rabbits. | the distribution of parasite populations in their hosts has been the subject of a number of mathematical analyses and it has been found that these distributions are generally nonrandom and overdispersed. data on the recovery of trichinella spiralis in the laboratory from 371 outbred rabbits were examined. the distribution of their parasite burden was overdispersed and best fit by a negative binomial frequency distribution. the intensity of the infections was almost totally independent of the dos ... | 1980 | 7463249 |
| concurrent infections of hymenolepis diminuta and trichinella spiralis in the rat intestine. | the intestinal distribution of trichinella spiralis and hymenolepis diminuta in rats was studied in single and concurrent infections. results showed that the location of t. spiralis was not significantly changed in concurrent infections, but higher populations of t. spiralis in single and concurrent infections resulted in a posterior shift in position. trichinella spiralis affected h. diminuta distribution significantly by causing a posterior shift in the position of scoleces and biomass and a l ... | 1980 | 7463246 |
| regional blood flow and the localization of lymphoblasts in the small intestine of the mouse. ii. the effects of a primary enteric infection with trichinella spiralis. | the localization of 125i-udr-labelled mesenteric lymph node cells in the small intestine and the fraction of the cardiac output delivered to this organ in mice has been examined. concurrent measurements of these two phenomena in normal animals showed that there was a significant correlation between the localization of lymphoblasts and the distribution of regional blood flow along the small intestine. in mice undergoing enteric infection with trichinella spiralis, however, the nature of the conne ... | 1980 | 7461718 |
| study of the kinetics of globule leucocytes in the intestinal epithelium of rats after single or double infection with trichinella spiralis. | in a previous study we suggested that intestinal globule leucocytes (gl) in the mouse represent a cell population independent of the intestinal mast cells (imc). in this paper we examined the interdependence of imc and gl in the rat and also the kinetics of gl in the intestinal epithelium. for this purpose rats received a single or double infection with the nematode trichinella spiralis. after the double infection worms were rapidly expelled. the numbers of imc and gl were related to the degree ... | 1980 | 7426383 |
| altered lysophospholipase b responsiveness in lactating mice infected with intestinal nematode parasites. | lactating and nulliparous outbred swiss (cf-1 strain) mice were infected at 12-16 weeks of age with nippostrongylus brasiliensis or trichinella spiralis. lysophospholipase b levels in the intestinal tissue and faecal pellets were greatly in infected lactating mice in contrast to infected nulliparous mice. correlated with these depressions in lysophospholipase levels were markedly reduced numbers of bone-marrow eosinophils in infected lactating mice. although the peak levels of lysophospholipase ... | 1980 | 7422360 |
| changing proteins on the surface of a parasitic nematode. | most of the organisms of the phylum nematoda are free living, but some are animal or plant parasites of major importance to man. during their life cycle all nematodes undergo a series of moults in which they shed an external cuticle, consisting of an outermost membrane-like layer of unknown composition and a series of fibrillar layers similar to collagens. because of this structure, the cuticle has been viewed as an acellular exoskeleton with rather inert molecular components. however, observati ... | 1980 | 7422005 |
| distribution of trichinella spiralis in muscles of the mouse. | 1980 | 7420250 | |
| preliminary studies on the course of a trichinella spiralis infection in athymic, nude rats. | 1980 | 7420247 | |
| concurrent infections of trichinella spiralis and toxoplasma gondii in mice. | concurrent infections with two parasites: a nematode, trichinella spiralis, and a protozoon. toxoplasma gondii, were investigated. antibody production (total immunoglobulin and igm) was similar in double and single infections. however, the number of toxoplasma cysts in the brains of mice infected with trichinella and challenged 1-6 weeks later with toxoplasma was higher than in mice infected with toxoplasma alone, while mice infected with toxoplasma and challenged 4-14 days later with trichinel ... | 1980 | 7415416 |
| rapid expulsion of trichinella spiralis: coinduction by using antigenic extracts of larvae and intestinal stimulation with an unrelated parasite. | the injection of cell-free extracts of larval trichinella spiralis with freund complete adjuvant immunized rats against a challenge infection with t. spiralis. protection was expressed by a reduction of adult worms in the intestines 8 days after a challenge infection. the quantitatively more important rapid expulsion reaction could also be produced by immunization with antigen, provided immunized rats were also given an intestinal priming infection with adult trichinella spiralis or an unrelated ... | 1980 | 7399702 |
| requirement for two discrete stimuli for induction of the intestinal rapid expulsion response against trichinella spiralis in rats. | rats subjected to a 7-day abbreviated enteral infection with trichinella spiralis subsequently reject more than 90% of a challenge infection within 24 h. this process is known as rapid expulsion. in these experiments parabiotic rats were used to examine the factors that establish rapid expulsion in the intestine. induction with low to moderate doses of worms required exposure to two separate stimuli. these initiated different responses; one was readily transferred between parabiotic rats, wherea ... | 1980 | 7399701 |
| [frequency and significance of parasitic infections in refugees from vietnam (author's transl)]. | in the course of the medical care which is provided for the refugees from southeast asia 100 persons were tested for intestinal parasites (helminths and protozoa). in addition serum samples were obtained from 72 of these and tested in several tests (cft, fat, iha and sft) using antigens of entamoeba histolytica, leishmania donovani, toxoplasma gondii, schistosoma spp., fasciola hepatica, echinococcus spp., trichinella spiralis and litomosoides carinii. in 49 persons infections with one, two or ... | 1980 | 7395245 |
| intestinal distribution of trichinella spiralis in rats. | intestinal distribution of trichinella spiralis was studied in mature and suckling sprague-dawley rats. position of trichinella along the small intestine was defined by a median value for the population. a range, 90% of total population, gave a relatively precise determination of microhabitat width. the normal position of trichinella following an oral infection is in the duodenum, but position of trichinella in mature rats is more anterior than position of trichinella in suckling rats. intestina ... | 1980 | 7391890 |
| systemic anti-inflammatory effect associated with enteric trichinellosis in the rat. | the hypothesis tested was that enteric parasites that induce local inflammation in their host suppress inflammatory reactions at distant sites. a technique was developed to demonstrate, quantitatively, such an anti-inflammatory component. the systemic antiphlogistic effect produced by the intestinal stages of trichinella spiralis was studied and compared with that caused by dexamethasone, a synthetic adrenocortical steroid. inflammation was measured (dry weight, protein content, myeloperoxidase ... | 1980 | 7391884 |
| eimeria nieschulzi and trichinella spiralis: analysis of concurrent infection in the rat. | 1980 | 7389855 | |
| phospholipase b levels in fecal pellets from mice infected with trichinella spiralis, hymenolepis nana, and schistosoma mansoni. | fecal pellets of mice infected with trichinella spiralis, hymenolepis nana, and schistosoma mansoni have been found to contain high levels of phospholipase b activity. the rise, time course and decline of the enzymatic content of the pellets correlate with the known patterns of intestinal injury and reaction due to the parasites or their eggs. treatment with drugs (thiabendazole, niclosamide, niridazole) which are effective in suppressing the infection also prevents the rise, or causes an early ... | 1980 | 7386719 |
| immunologically mediated, non-specific interactions between the intestinal phases of trichinella spiralis and nippostrongylus brasiliensis in the mouse. | interactions between infections of trichinella spiralis and nippostrongylus brasiliensis were studied in the nih strain of mouse which is known to react strongly to t. spiralis. the course of n. brasiliensis infection in this strain of mouse is described and expulsion is shown to be accelerated in immunized mice and inhibited in cortisone-treated mice. there was no evidence of inter-specific competition between the two species of worm in concurrent infections; the number and location of adults o ... | 1980 | 7383710 |
| effects of the host immune response on the longevity, fecundity and position in the intestine of trichinella spiralis in mice. | in female nih strain mice, expulsion of a primary infection of the nematode trichinella spiralis began on day 8 and was virtually complete by day 14 of infection. in secondary and tertiary infections, the number of larvae which established in the intestine was normal, but expulsion began on day 6 and was complete on day 10. in a primary infection the shedding of larvae by female worms began on day 5, reached its peak on days 6--7, began to decrease on day 8 and was minimal by day 10. in secondar ... | 1980 | 7383709 |
| hypereosinophilia in rats with trichinella spiralis infections. | 1980 | 7378271 | |
| [evaluation of helminth intradermal tests in comparison to coproovoscopic surveys]. | 1600 subjects connected with mining were divided into 6 groups and examined because of intestinal parasites. there were: surface miners underground miners, retired miners and two groups of school-children up to 14 years old and from 14-17 years old, and persons not connected with the miners' work. the one control group consisted of 150 persons with negative coproscopical investigations, the other consisted of 112 persons, who were clinically healthy. the coproscopical investigations, morphologic ... | 1980 | 7377624 |
| trichinella thrives in both oxidative and glycolytic human muscle fibres. | in a deltoid biopsy from a severe case of human trichinosis the larvae of trichinella spiralis did not exhibit any predilection for any particular fibre type. type i and type ii fibres were involved with a frequency proportionate to their distribution in the muscle sampled. | 1980 | 7373326 |
| immunity to trichinella spiralis in irradiated mice. | 1980 | 7372390 | |
| trichinella spiralis infection in animals genetically selected for high and low antibody production. studies on intestinal pathology. | specific antibody response and histopathological changes in the small intestine were studied in mice genetically selected for high and low antibody production (hl and ll, respectively) after oral infection with 50 muscle larvae of trichinella spiralis. specific antibody response, measured during the first 20 days after infection in the passive cutaneous anaphylaxis assay and the immunofluorescence test was high in hl and low in ll mice. the response of macrophages, intestinal mast cells, globule ... | 1980 | 7372360 |
| studies on in vitro larvaposition by adult trichinella spiralis. | 1980 | 7365641 | |
| chemical attraction in the genus trichinella. | chemical attraction in the genus trichinella was studied in vitro. male adult worms of trichinella spiralis, t. spiralis var. pseudospiralis, and trichinella sp. isolate (polar bear isolate) were attracted to females of their own isolates. the intensity of heterosexual chemical attraction between t. spiralis and the trichinella sp. isolate was similar, whereas t. spiralis var. pseudospiralis males were attracted less by either t. spiralis or the trichinella sp. isolate females. female worms of a ... | 1980 | 7365640 |
| surface morphology of trichinella spiralis by scanning electron microscopy. | the surface morphology of larval and adult trichinella spiralis was studied by scanning electron microsocopy (sem) of fixed, dried, and metal-coated specimens. the results are compared with those found earlier by various investigators using light and transmission electron microscopy. some morphological features reported here are revealed uniquely by sem. these include the pores of the cephalic sense organs, the character of secondary cuticular folds, variations of the hypodermal gland cell openi ... | 1980 | 7365639 |
| trichinella spiralis: comparison with an arctic isolate. | 1980 | 7364011 | |
| survival of trichinella spiralis larvae in deep-frozen wolf tissue. | 1980 | 7363256 | |
| mebendazole therapy of parenteral trichinellosis. | mebendazole was highly effective against the helminth parasite trichinella spiralis in mice subjected to a 3-day course of treatment during the invasive and encystment phases of experimental trichinellosis. when treatment began either 2 or 4 weeks after the mice were inoculated with parasites, the number of larvae developing in the host musculature was greatly reduced by twice-daily oral administration of 3.125, 6.25, or 12.5 milligrams of mebendazole per kilogram of body weight. | 1980 | 7355285 |
| host defense mechanisms against trichinella spiralis infection in the mouse: eosinophil-mediated destruction of newborn larvae in vitro. | 1980 | 7350232 | |
| intestinal mast cell response in thymectomised and normal mice infected with trichinella spiralis. | in nih mice, expulsion of trichinella spiralis from the small intestine and increase in intestinal mast cells were each dependent on the presence of t-lymphocytes. both changes were deficient in thymectomised mice but could be largely restored by reconstitution of thymectomised mice with syngenetic mesenteric lymph node cells. in both nih and balb/c mice the majority of the increased number of mast cells occurred within the intestinal epithelium. in nih mice increase in the number of intestinal ... | 1981 | 7344269 |
| evidence, nature, and implications of the constitutive resistance to trichinella spiralis in gallinaceous birds. | white leghorn chickens and mice were orally infected with trichinella spiralis larvae and their digestive tracts were examined for parasites at postinfection hours (pih) 5 and 10, and at postinfection days (pid) 1, 2, 4, 6, and 8. evacuated feces were examined at pih 5 and 10 and at pid 1, and blood was examined at pid 4, 6, and 8. with the exception of trichinae in the digestive tract (9 at pih 5 and 2 at pih 10), parasites were not recovered from chickens. all mice had abundant parasites in th ... | 1981 | 7337291 |
| [growth and fertility of trichinella spiralis developed from larvae treated with noviben and panacur in vivo]. | 1981 | 7336738 | |
| the effects of host sex on enteric response to infection with trichinella spiralis. | the effects of host sex on enteric inflammatory response to primary infection with trichinella spiralis were examined. enteritis in female mice was greater than that in male mice on days 7, 9 and 11 postinfection (pi) and similar to that in male mice by day 13 pi. male and female mice given daily injections of 33 or 66 mg/kilo of cortisone acetate exhibited significantly reduced enteritis on days 7, 9 and 11 pi below that seen in uninjected, male and female mice. on days 7, 9 and 11 pi larviposi ... | 1981 | 7328465 |
| a comparative study of trichinella spiralis (owen, 1835) and trichinella pseudospiralis (garkavi, 1972). | 1981 | 7328464 | |
| gut propulsion in mice infected with trichinella spiralis. | previous investigators have shown that trichinella spiralis increases intestinal motility and propulsion. we report here that primary infection with t. spiralis in the mouse increased gut propulsion, measured by the movement of nonabsorbable chromatography beads, on day 5 after infection but not 9 days after infection. both cortisone acetate, an anti-inflammatory agent, and lomotil, which reduced gut motility, could suppress the increase in gut propulsion seen 5 days after infection. the results ... | 1981 | 7328463 |
| trichinella spiralis in rats: in vivo effects of the bile and in vitro action of secretory iga from bile. | the biliary secretion of rats is diverted from the choledoch duct to the bladder. these rats are resuscitated by sub-cutaneous injections of a salt solution and then infected with trichinella spiralis larvae. it is shown that the number of adult worms is increased (+ 66%); as is the female larvae production (+ 51%); the females' length is also increased (+ 25%). 40 days after the infection the number of muscular larvae is considerably increased (+ 79%) in comparison with control rats. secretory ... | 1981 | 7325526 |
| characterization of surface antigens of trichinella spiralis infective larvae. | infective larvae of trichinella spiralis were surface-labelled with radioactive iodine, and the products were characterized biochemically and immunochemically. the labelled material was restricted to two basic subunits: a lentil lectin-adherent glycoprotein (gp), mol. wt 47k, and a lentil lectin-nonadherent protein fraction (p), mol. wt 55k. both of these form homologous dimers through as yet unspecified covalent bonds to yield gp90 and p105. gp is further polymerized into higher molecular weigh ... | 1981 | 7322614 |
| the effect of trichinella spiralis on the rate of clearance of 51cr-labelled sheep red blood cells and 125i-polyvinyl pyrrolidone from the bloodstream of mice. | mice infected for one to eight weeks with trichinella spiralis cleared either 51cr-labelled sheep red blood cells (srbc) or 125i-polyvinyl pyrrolidone (pvp) given intravenously. pvp was cleared more rapidly from the blood of mice infected for one week than from uninfected mice with older infections which behaved in a similar manner to the controls. srbc were consistently cleared faster from the blood of mice infected for one week than from normal mice. if the infections were older than this a mo ... | 1981 | 7310111 |
| partial purification and characterization of protection-inducing antigens from the muscle larva of trichinella spiralis by molecular sizing chromatography and preparative flatbed isoelectric focusing. | the soluble portion of a large particle fraction which was derived from the muscle larva of t. spiralis was subjected to molecular sizing column chromatography using sephacryl s-200. five major peaks of 280 nm absorbing material were obtained. analysis by immunoelectrophoresis revealed that each peak contained antigens, with the majority of them occurring in peaks 3, 4 and 5. preliminary studies indicated that peak 4(mol. wt range 20 000--10 000) contained protection-inducing antigens. crossed-i ... | 1981 | 7301410 |
| chemical attraction in the absence of worm-mediated tactile behavior in trichinella spiralis. | in vitro chemical attraction of trichinella spiralis was studied using as migrators individual male or female worms. both male and female worms exhibited a dose-dependent behavior at target doses of 20 to 80 worms, no significant differences in response at doses of 80 to 200 worms, and an inhibition of movement at doses of 200 to 400 worms. single males were attracted less to a mixture of males and females as the source of pheromone than single males to a female source. single females did not mo ... | 1981 | 7299579 |
| comparative analysis of mobility and ultrastructure of intramuscular larvae of trichinella spiralis and trichinella pseudospiralis. | the muscle phase of trichinella spiralis and trichinella pseudospiralis was studied by using scanning electron microscope techniques, closed circuit television, and video tape recording. the complete absence of any cyst structure including the pseudocapsule allows t. pseudospiralis to move freely between the muscle layers. its rate of activity, measured as distance moved between two points, was 2.83 mm/min compared to that of the encysted t. spiralis larvae which was 0.237 mm/min. there was an a ... | 1981 | 7299578 |
| immunopathological changes in the kidneys of mice experimentally infected with trichinella spiralis. | 1981 | 7299149 | |
| haematological changes evoked by trichinella spiralis as an index of the course of trichinellosis in germfree and conventional mice. | 1980 | 7272831 | |
| macrophage migration inhibition test in germfree and conventional mice infected with trichinella spiralis larvae. | 1980 | 7272830 | |
| scanning electron microscope studies in the small intestine epithelium of germfree and conventional mice after infection with trichinella spiralis. | 1980 | 7272829 | |
| reactivity of lymphocytes in germfree and conventional mice infected with trichinella spiralis. | 1980 | 7272823 | |
| lymphocytotoxicity of mouse sera in the course of experimental infection with trichinella spiralis and trichinella pseudospiralis. | 1980 | 7272822 | |
| the effects of host sex and hormones on trichinella spiralis in the mouse. | the effects of host's sex and hormones on the number of adult trichinella spiralis in the small intestine, the number of migratory larvae produced in vitro by adult female worms, and the number of muscle larvae per gram of body weight were examined in cd-1 swiss white mice. nongonadectomized (intact) male mice housed greater numbers of adult worms and a greater number of muscle larvae per gram of body weight than did intact female mice. adult female worms isolated from intact male mice deposited ... | 1981 | 7264840 |
| recovery of eosinophils from the peritoneal cavity of the guinea pig. | we studied the effects of various conditions on the recovery of eosinophils from the peritoneal cavity of guinea pigs repeatedly lavaged with saline. we compared the effects of ether and halothane on eosinophil production in guinea pigs either lavaged with saline alone or receiving an injection of polymyxin b before saline lavage. with both anesthetics polymyxin b caused a rapid and consistent increase in eosinophil production, although neutrophils were present. with halothane anesthesia, saline ... | 1981 | 7264308 |
| the reaction of mouse muscle cells during simultaneous trichinella spiralis and trichinella pseudospiralis infection. | 1980 | 7246268 | |
| trichinella spiralis: generation in the presence of rat serum of factors chemotactic for rat cells. | 1981 | 7238726 | |
| [the large island--impressions of a medical parasitological trip to madagascar]. | the course of an investigation trip through madagascar is sketched. it allowed to analyze the parasitological situation. it is explained with the sociological and economical facts and the unusual fauna of this island. the two biggest problems are malaria tropica and schistosomatosis (bilharziasis). further, ancylostoma, ascaris, taeniids, and wuchereria occur. plague is rare. fasciola gigantica has been introduced since short time only. introduction of other parasites must be feared. sleeping il ... | 1981 | 7235291 |
| an in vitro screening test for compounds active against the parenteral stages of trichinella spiralis. | a new in vitro screening test for compounds showing activity against the tissue stages of trichinella spiralis is described. in this test freshly decapsulated larvae of the parasite are exposed to low concentrations of experimental compound in a medium capable of supporting th partial development of the worms. the screen which does not require elaborate continuous flow equipment nor special gas phase detects the activity of those compounds known to be effective against the parenteral stages of t ... | 1981 | 7233549 |
| influence of routine extraction procedures in the composition of trichinella spiralis extracts. | 1981 | 7229810 | |
| the location of parasites within their hosts: factors affecting longitudinal distribution of trichinella spiralis in the small intestine of mice. | 1981 | 7228485 | |
| modulation of particle uptake in trichinella spiralis-infected mice. | mice were infected with 170 trichinella spiralis larvae, and their blood clearance of carbon particles was studied 4, 7, 13, 32, and 135 days later and compared with that of noninfected control mice. clearance in mice with a 4-day-old infection was comparable to that in the controls; clearances in mice with 7- and 13-day-old infections were increasingly accelerated and significantly different from that in the controls; clearances in mice with 32- and 135-day old infections were proportionally in ... | 1980 | 7228390 |
| changes in intestinal fluid transport and immune responses to enterotoxins due to concomitant parasitic infection. | the effect of a parasitic infection on enterotoxic diarrhea and on local and systemic formation of antibody to the toxin after immunization was studied in mice. trichinella spiralis infection was chosen as the model, since the effects of the parasite when residing in both intestinal and extraintestinal sites can be studied. it was found that during the intestinal stage of the infection, the fluid response to cholera toxin as well as dibutyryl-cyclic adenosine 3',5' -monophosphate was greatly enh ... | 1980 | 7228388 |
| a comparison of the anthelmintic effects of oxfendazole and oxibendazole on trichinella spiralis in mice. | oxfendazole was shown to be a very potent agent in killing trichinella spiralis. a single dose of 1.6 mg/kg per os killed 99% of preadults. adults were much more resistant; 25 mg/kg killed 56%, even 3,200 mg/kg only killed 94%. developing and encysted muscle larvae were also killed; 7 x 50 mg/kg killed 99% and 98%, respectively. oxibendazole was less effective. 6.25 mg/kg killed 99% of preadults, and 3,200 mg/kg killed only 69% of adults. although oxibendazole also killed developing and encysted ... | 1980 | 7218114 |
| [an ultrastructural study of spermatogenesis in trichinella spiralis owen 1835 (nématode trichuroide) (author's transl)]. | the ultrastructural study of spermatogenesis in t. spiralis demonstrated the main characteristics of the male germ cells in the class nematoda, i.e. lack of flagella, lack of reconstitution of the nuclear envelope after the meiotic divisions, and atypical structure of the centriole. the spermatozoon of t. spiralis was compared with previous classifications of the nematoda spermatozoa. | 1981 | 7210821 |
| reversibility of the effects of the host immune response on the intestinal phase of trichinella spiralis in the mouse, following transplantation to a new host. | on day 10 of a primary infection of trichinella spiralis in nih mice, when adult worms were in the process of being expelled, their fecundity was markedly depressed. upon transplantation to new host mice, the worms were able to establish successfully in their usual position in the anterior small intestine, even if originally recovered from the large intestine of mice expelling their worms, and these worms fully recovered their fecundity after 7 days in recipients. on day 5 of secondary and terti ... | 1981 | 7208103 |
| trichinella spiralis: proteins and antigens isolated from a large-particle fraction derived from the muscle larva. | 1981 | 7202634 | |
| the ultrastructure of the reproductive system, and the oogenesis of two day-old, fertilized females of trichinella spiralis and t. nativa. | the authors observed no difference in the ultrastructural topography of the female reproductive system of t. nativa and t. spiralis, and in the oogenesis. there were both dense and lucid areas produced by invaginations of the oolemma in the cytoplasm of primary oocytes. the oolemma contained fibril-covered microvilli. large granules differentiated in mature oocytes by an incorporation of smaller granules into transparent areas of the cytoplasm which became membrane-bound. the sheath covering ooc ... | 1982 | 7199505 |
| euparal as a permanent mounting medium for helminth eggs and proglottids. | the importance of euparal as a permanent mounting medium for eggs of parasites and the process of making permanent slides are analyzed and discussed in detail. studies show that helminth eggs mounted in euparal exhibit excellent optical and drying properties. euparal also can be used to identify proglottids of taenia species and to examine for the presence of trichinella spiralis in suspicious muscle biopsies. | 1980 | 7196920 |
| genetic control of immunity to parasites: adoptive transfer of immunity between inbred strains of mice characterized by rapid and slow immune expulsion of trichinella spiralis. | adoptive transfer of immunity with immune mesenteric lymph node cells (imlnc) was used to analyse the roles of immune and inflammatory events in determining the strain-characteristic time of expulsion of trichinella spiralis from mice. transfer of imlnc within and between three rapidly responding strains (nih, swr, dba1-all h-2q) resulted in accelerated worm expulsion, worm loss commencing before day 8 in each case. when nih cells were transferred to slow-responder b10 congenic mice (b10g-h-2q) ... | 1980 | 7194468 |
| [trichinosis]. | in spite of a decreased occurrence of trichinella spiralis with pigs and wild boars in the federal republic of germany raw or underdone pork is the primary source of infection for man. but as the epidemic of ebermannstadt has shown, trichinelliasis occasionally occurs nowadays. besides, there is a danger of infection when travelling to countries with insufficient meat hygiene. after initial enteritis the characteristic symptomatology appears: facial edemas, myalgia, fever, and hypereosinophilia. ... | 1980 | 7191393 |
| [recovery of pork meat infected with trichinella spiralis using gamma radiation]. | 1982 | 7187230 | |
| [survival and infective capacity of trichinella spiralis in the macroenvironment]. | 1982 | 7184094 | |
| serologic survey for certain zoonotic diseases in black bears in california. | black bears (ursus americanus) from 3 geographic areas of california were tested for antibodies against agents of 6 zoonotic diseases: toxoplasmosis (indirect hemagglutination), q fever (microagglutination), trichinosis (latex particle agglutination), botulism (passive hemagglutination), leptospirosis (plate agglutination), and plague (enzyme-linked immunosorbent assay). of 149 sera tested, 40 (27%) were positive for toxoplasma gondii antibodies and 25 (17%) had antibodies against coxiella burne ... | 1982 | 7174445 |
| parasitisms among wild swine in southeastern united states. | examination of 187 wild swine from 20 locations in 11 southeastern states revealed at least 25 species of endoparasites and 7 species of ectoparasites. three parasites of public health importance (sarcoptes scabiei, spirometra sp, and toxoplasma gondii) were disclosed by this study. the absence of trichinella spiralis indicates that wild swine in the southeast are not a reservoir for tr spiralis. | 1982 | 7174443 |
| effects of nematode larvae (trichinella spiralis and toxocara canis) on b-glucuronidase enzyme in experimentally infected mice. | 1982 | 7153552 | |
| intestinal mast cells and their relation to mesenteric lymph nodes. | the data presented in this paper support a common source for intestinal mast cells in intestinal mucosae. imc precursors and/or mastocytopoietic factors of as yet unknown origin could be transferred by immune mesenteric lymph node (imln) cells of thymus-bearing mice. the differentiated locally or induced mastocytopoiesis in trichinella spiralis infected mucosal sites, but only in animals with a normal thymus function. antigen-stimulated precursor cells either in the gut or in the mesenteric lymp ... | 1982 | 7148570 |