Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| hymenolepis nana: immunity against oncosphere challenge in mice previously given viable or non-viable oncospheres of h. nana, h. diminuta, h. microstoma and taenia taeniaeformis. | when mice, previously given oral inoculation with viable oncospheres of the heterologous cestode species (hymenolepis diminuta, h. microstoma, taenia taeniaeformis) and the homologous one (h. nana), were challenged with oncospheres of h. nana 4 days after the primary inoculation, they showed strong and complete resistance to h. nana challenge, respectively. however, the resistance was not evoked in mice given either infective eggs of toxocara canis or non-viable oncospheres of all cestode specie ... | 1991 | 1869358 |
| families, parks, gardens and toxocariasis. | toxocara canis antibody titres were measured in members of 30 families. 73/140 (52.1%) family members were seropositive for t. canis at a dilution greater than or equal to 1:50 and 11 (7.8%) had reciprocal titres greater than or equal to 800. toxocara ova were sought (a) in relation to the 30 families and (b) in the community. no toxocara ova were found in household dust samples. 38% of family gardens contained toxocara ova while 6% of soil samples from public parks and open spaces around housin ... | 1991 | 1853172 |
| parasitism of toxocara canis larvae in japanese quails by inoculation of the ascarid eggs. | the distribution of t. canis larvae and pathological changes caused by them were studied in japanese quails orally inoculated with 1,500, 4,000 or 15,000 embryonated eggs. larvae were distributed mainly in the liver and, to lesser extent, in the muscles, brain, eyes and other organs. the number of larvae varied from 7 to 3,346, and from 1 to 288 in the liver and muscles (breast and legs), respectively. a small number of larvae were also recovered from the heart, gizzard, brain and eyes. in the g ... | 1991 | 1836373 |
| helper activity for immunoglobulin synthesis of t helper type 1 (th1) and th2 human t cell clones: the help of th1 clones is limited by their cytolytic capacity. | a large number of cd4+ human t helper type 1 (th1) clones specific for purified protein derivative and of th2 clones specific for the excretory/secretory antigen of toxocara canis, derived from the same individuals, were analyzed for both cytotoxic capacity and helper function for immunoglobulin (ig) synthesis. the great majority of th1, but only a minority of th2 clones exhibited cytolytic activity. all th2 (noncytolytic) clones induced igm, igg, iga, and ige synthesis by autologous b cells in ... | 1991 | 1833502 |
| t cells, ige antibodies, cytokines and allergic inflammation. | t helper cell (th) subsets producing interleukin 4 (il-4) or gamma interferon (ifn) play a reciprocal role in the regulation of human ige synthesis. though necessary, il-4 alone was insufficient. patients with hyper-ige had significantly lower proportions of t-cells that produce ifn and tnf, but not il-2 or il-4. in patients with helminth infections or atopy production of ige and eosinophilia may result from expansion of th-2-like cells. t cell clones (tcc) specific for allergens and toxocara ca ... | 1991 | 1831617 |
| purified protein derivative of mycobacterium tuberculosis and excretory-secretory antigen(s) of toxocara canis expand in vitro human t cells with stable and opposite (type 1 t helper or type 2 t helper) profile of cytokine production. | a large series of t cell clones (tcc) specific for purified protein derivative (ppd) of mycobacterium tuberculosis (total 60) or toxocara canis excretory/secretory (tes) antigen (total 69) were established from the peripheral blood of two healthy individuals and analyzed for their profile of cytokine production in response to stimulation with either the specific antigen or the polyclonal activator phorbol myristate acetate plus anti-cd3 antibody. under both these experimental conditions, the gre ... | 1991 | 1829097 |
| larvicidal activity of actinomycete isolate against toxocara canis. | a soil isolate of actinomycete, strain s-70, revealing presence of plasmid(s) was placed in the genus streptomyces according to the wall composition and morphology. the toxicity of s-70 grown on two fermentation media, glucose-asparagine broth (gab) and malt extract-yeast extract broth (mye), against infective larvae of toxocara canis was assessed. the use of mortality test has provided a sensitive and reproducible bioassay. the results suggest high larvicidal activity of the streptomyces crude ... | 1991 | 1822469 |
| application of the western blotting procedure for the immunodiagnosis of human toxocariasis. | to improve the immunodiagnosis of human toxocaral disease, a sensitive and specific assay using the western blotting procedure (wb) with excretory-secretory antigens from toxocara canis larvae (tes) was developed and compared with the standard enzyme-linked immunosorbent assay method (tes-elisa) using the same antigens. we tested groups of sera from laboratory animals or patients presenting with toxocariasis or other helminthic diseases and a group of sera from people dwelling in an area endemic ... | 1991 | 1805214 |
| effects of heterologous helminth infections on passive transfer of immunity using a mouse monoclonal ige antibody against schistosoma japonicum. | passive transfer of immunity using a mouse monoclonal ige antibody against schistosoma japonicum was found to be enhanced by heterologous helminth infections. balb/c mice were infected with toxocara canis or nippostrongylus brasiliensis so as to induce eosinophilia prior to a challenge infection with s. japonicum. recovery of adult schistosomes decreased in a group of mice that had been infected with t. canis and challenged with cercariae at the cutaneous site of sensitization with the ige antib ... | 1991 | 1805210 |
| prevalence of endoparasites in dog faecal deposits in jordan. | of 756 dog faecal deposits collected from the road side and public places in five jordanian governorates 466 (61.6%) harboured parasite ova, oocysts and/or larvae. of these, 67.7%, 26.8%, 4.1% and 1.4% revealed one, two, three and four different types of parasite ova, oocysts or larvae in the same sample, respectively. examination of the infected samples revealed that 44.1% contained taeniid ova, 19.8% dipylidium caninum, 19% toxocara canis, 8% sarcocystis spp. oocysts, 5% hookworm larvae, 1.5% ... | 1991 | 1795094 |
| hatching of second-stage larvae of toxocara canis: a rapid method for processing large numbers of worms. | a method for hatching second-stage larvae of toxocara canis is described. whole adult worms are processed by centrifugation in the presence of hypochlorite which allows the grinding step to be eliminated. the technique is more rapid and a high yield is obtained. | 1991 | 1795093 |
| fetal response to maternal ascariasis as evidenced by anti ascaris lumbricoides igm antibodies in the cord blood. | the immune response of the fetus to maternal infection with ascaris lumbricoides was studied by estimating igg and igm antibodies, using elisa, in 28 paired samples of mother and cord blood. a. lumbricoides adult male, cuticle and unembryonated egg antigen was used. toxocara canis larva antigen was used as a specificity control. presence of igg in the cord blood does not signify fetal response, but the presence of igm antibodies does. igm antibodies to ascaris adult male antigen were present in ... | 1991 | 1785284 |
| comparison of isolates and species of toxocara and toxascaris by biosynthetic labelling of somatic and es proteins from infective larvae. | infective-stage larvae of three different isolates of toxocara canis were intrinsically ([35s]methionine) labelled in culture, to determine the presence of similarities or differences in the somatic and es antigens expressed between larvae derived from different hosts and different geographical regions. two other closely related ascaridids, toxascaris leonina which infects cats and dogs, and toxocara vitulorum (neoascaris vitulorum) which infects cattle, were also compared to t. canis larvae by ... | 1991 | 1780182 |
| immunodiagnosis of toxocarosis in humans: evaluation of a new enzyme-linked immunosorbent assay kit. | excretory/secretory (e/s) antigen derived from second-stage larvae of toxocara canis maintained in defined medium in vitro has been well established worldwide for the immunodiagnosis of human toxocarosis by enzyme-linked immunosorbent assay. such an enzyme-linked immunosorbent assay, based on the detection of human anti-t. canis (e/s antigen) serum immunoglobulin g, has recently been commercialized by biokema-affinity products (crissier-lausanne, switzerland). this commercial test kit was evalua ... | 1991 | 1774303 |
| the prevalence of toxocara canis ova in soil samples from parks and gardens in the london area. | toxocara canis is an ascarid parasite of the dog. human infection is acquired when ova of t. canis are ingested. parks and play areas contaminated with dog faeces are recognised as potential sources of infection. five hundred and twenty one soil samples were examined from fifteen parks and gardens in the greater london area to establish the prevalence of soil contamination in those facilities. samples were examined using a magnesium sulphate floatation method. t. canis ova were found in 6.3% of ... | 1991 | 1767007 |
| the effect of the initial inoculum dose and post-infection period on larval dispersal in experimental murine toxocariasis. | the distribution of toxocara canis larvae throughout the tissues of mice was studied in three groups of fourty mice each using three inocula sizes, (200/500 and 1000 eggs/mice). the results obtained revealed a significant interaction between the duration of infection, the inoculum size and the dispersal rate of larvae through the examined organs of experimented with mice. | 1991 | 1765691 |
| evaluation of a beef-based chewable formulation of pyrantel pamoate against induced and natural infections of hookworms and ascarids in dogs. | pyrantel pamoate, formulated in a beef-based chewable tablet, was evaluated for efficacy in dogs against induced and natural infections of toxocara canis, toxascaris leonina, ancylostoma caninum and uncinaria stenocephala. dose titration trials were conducted in canada, the uk and germany in dogs treated with pyrantel (as pamoate salt) at 0, 2.5, 5 or 10 mg kg-1 body weight. these studies showed that a dose rate of 2.5 mg kg-1, the efficacy of pyrantel against adult t. canis, t. leonina, u. sten ... | 1991 | 1763481 |
| toxocara canis and pregnancy in mice. | 1991 | 1755075 | |
| identification of dirofilaria immitis-infected dogs with a coagglutination assay. | the presence of dirofilaria immitis excretory-secretory (es) products was detected in the urine of infected dogs using a coagglutination assay. urine samples from 30 naturally infected dogs were positive. seventeen of them were microfilaremic, whereas 13 had become amicrofilaremic after receiving 2 courses of diethylcarbamazine. urine samples from 20 dogs infected with other parasites, dipetalonema reconditum (7), toxocara canis (5), and ancylostoma caninum (8), and urine samples from 20 healthy ... | 1992 | 1738064 |
| larval exoantigens from ascarid nematodes are potent inducers of histamine release from human blood basophils. | histamine release (hr) from washed human blood cells after challenge with the excretory-secretory antigens (es) of the parasitic nematodes toxocara canis and ascaris suum was studied, employing a recently developed microfibre-based assay combined with hyperosmolar release media for maximal sensitivity. blood samples were obtained from 30 patients suspected of parasite infection and 11 healthy volunteers serving as controls. specific antibodies of ige, igg1 and igg4 subclasses were determined by ... | 1991 | 1723345 |
| monoclonal antibodies to secreted antigens of brugia malayi define a cross-reactive non-phosphocholine determinant on helminth parasites. | the excretory-secretory (es) antigens of the filarial parasite brugia malayi adult (bma) and microfilariae (mf) were analysed for differences in their protein composition by two-dimensional gel electrophoresis. both bma and mf biosynthetically labelled with [3h]-leucine released a 200 kd molecule with pi (isoelectric point) ranging from 5.1 to 6.8. a monoclonal antibody (moab) to phosphocholine (pc) immunoprecipitated the 200 kd molecule with a pi of 5.1-5.3 from both bma and mf. immunization of ... | 1991 | 1717373 |
| characterization of monoclonal antibodies to young-adult worms of angiostrongylus cantonensis. | three igg1 and one igg2a monoclonal antibodies were obtained by fusion of ns-1 cells with spleen cells of balb/c mice immunized with young-adult worm antigen of a. cantonensis. these 4 monoclonal antibodies were specific to a. cantonensis without cross-reactivity to any antigens of toxocara canis, ascaris suum, clonorchis sinensis, dirofilaria immitis, paragonimus westermani, gnathostoma spinigerum, strongyloides stercoralis and anisakis spp. detected by elisa. the affinity constants of monoclon ... | 1990 | 1701759 |
| in vivo changes of hemopoietic progenitors and the expression of the interleukin 5 gene in eosinophilic mice infected with toxocara canis. | it has been demonstrated that purified recombinant interleukin 5 (ril-5) supports the terminal differentiation and proliferation of eosinophilic precursors in vitro and plays an important role in increasing the functional activities of eosinophils. in this study, we examined the hemopoietic changes and analyzed murine (m) il-5 mrna expression in eosinophilic mice infected with the helminth toxocara canis. in eosinophilic mice, eosinophils increased in number in both bone marrow and spleen. howev ... | 1990 | 1699772 |
| the distribution and localization of the stage-specific gp31 antigen from infective ostertagia circumcincta larvae. | the 31,000 mol. wt glycoprotein (gp31) antigen of infective third-stage (l3) ostertagia circumcincta larvae was shown, by surface labelling experiments and immunofluorescent antibody staining of whole larvae and larval sections, to be distributed internally. when transverse sections of l3 o. circumcincta, taken from the anterior pharyngeal region, were further examined by electron microscopy, after immunogold staining with rabbit anti-gp31 antiserum, the gp31 antigen was found to be specifically ... | 1990 | 1690183 |
| analysis of local antibody production in the vitreous humor of patients with severe uveitis. | we analyzed the local antibody production in vitreous humor samples collected during vitrectomy in patients with severe vision-threatening uveitis. in 24 patients, paired serum and undiluted vitreous humor samples were collected and tested for antibodies against toxoplasma gondii, herpes simplex virus, varicella-zoster virus, cytomegalovirus, epstein-barr virus, and toxocara canis. total igg and the goldmann-witmer coefficient were determined. the initial diagnosis of ocular toxoplasmosis could ... | 1991 | 1651055 |
| cross-reactions of sera from toxocara canis-infected mice with toxascaris leonina and ascaris suum antigens. | the elisa method using larval excretory-secretory (e/s) products and homogenized toxocara canis, toxascaris leonina and ascaris suum adult worm extract were used to determine possible cross-reactions in balb/c and c57bl/10 mice, inoculated with embryonated eggs or adult worm extract of t. canis in single and multiple doses. when we used sera of mice infected with embryonated eggs of t. canis against different heterologous antigens, we observed no cross-reactions in balb/c mice against a. suum e/ ... | 1992 | 1639565 |
| toxocara canis: a labile antigenic surface coat overlying the epicuticle of infective larvae. | an electron-dense coat covering the surface of toxocara canis infective-stage larvae is described. this coat readily binds to cationized ferritin and ruthenium red, indicating a net negative charge and mucopolysaccharide content, and can be visualized by immuno-electron microscopy only if cryosectioning is employed. monoclonal antibodies reactive to the surface of live larvae bind the surface coat but not the underlying cuticle in ultrathin cryosections. the surface coat is dissipated on exposur ... | 1992 | 1639165 |
| a method for the recovery of infective larvae from toxocara canis eggs for collection of larval secretory/excretory products. | 1992 | 1626874 | |
| acute eosinophilic pneumonia due to toxocariasis with bronchoalveolar lavage findings. | a previously healthy young man presented with breathlessness, diffuse pulmonary infiltrates on the chest x-ray film, and a high degree of peripheral blood eosinophilia. analysis of bronchoalveolar lavage (bal) fluid showed 64 percent eosinophils. a diagnosis of toxocariasis was eventually reached on the basis of a positive enzyme-linked immunosorbent assay (elisa) for toxocara canis. the routine performance of the elisa test for toxocara in the diagnostic approach to pulmonary infiltration with ... | 1992 | 1623771 |
| [ocular toxocara canis in a 30-year-old adult]. | pars plana vitrectomy was performed in a 30-year-old patient who presented a posterior traction detachment due to an inflammatory granuloma. the granuloma removed in toto during surgery revealed characteristic features of toxocariasis lesion (first case described in the literature). an elisa test performed on a vitreous sample was strongly positive. retinotomy around the granuloma was necessary to re-attach the retina and silicone oil was used as a tamponade for 4 months. va improved from hm to ... | 1992 | 1614145 |
| the prevalence of toxocara canis ova in soil samples from parks and gardens in the london area. | 1992 | 1609053 | |
| [myelitis caused by toxocara canis (larva migrans)]. | a young woman presented with recurrent myelitis associated with persistent eosinophilia in blood and csf. specific serological procedures in blood and csf led to the diagnosis of visceral larva migrans. the patient recovered after 21 days of treatment with diethylcarbamazine. to our knowledge, this is the second report of myelitis in the course of visceral larva migrans. | 1992 | 1604114 |
| the prevalence of toxocara canis ova in soil samples from parks and gardens in the london area. | 1992 | 1603928 | |
| efficacy of ivermectin and pyrantel pamoate combined in a chewable formulation against heartworm, hookworm, and ascarid infections in dogs. | eight trials were conducted in dogs to document the efficacy of ivermectin (6 micrograms/kg of body weight) and pyrantel pamoate (5 mg of active pyrantel/kg) in a beef-based chewable formulation against dirofilaria immitis, ancylostoma caninum, uncinaria stenocephala, toxocara canis, and toxascaris leonina. three studies involved induced infection with d immitis, and 5 studies involved induced or natural infection with hookworms and ascarids. in 3 intestinal parasite trials, the efficacy of the ... | 1992 | 1586021 |
| protein chromatographic study on adult ascaris lumbricoides, ascaris vitulorum and toxocara canis. | chromatographic analysis using sephacryl s-300 was done on protein extract of adult ascaris lumbricoides, a. vitulorum and toxocara canis worms. six fractions were separated from both ascaris species and nine from t. canis. fractions revealed a variety of molecular weights in relation to the three species of worms that ranged from 6,000-70,000 daltons. crude extract of t. canis showed cross reaction with both species of ascaris sera using double gel diffusion, while no reaction was obtained usin ... | 1992 | 1578165 |
| seroepidemiologic study of toxocariasis and strongyloidiasis in institutionalized mentally retarded adults. | serologic surveys for toxocara canis and strongyloides sp., as well as stool examinations for intestinal parasites, were conducted in a home for mentally retarded adults. evidence of parasitic infection was found in 30 (28.3%) of 106 residents; nine (8.5%) had positive toxocaral serology (enzyme-linked immunosorbent assay[elisa]), 1 (0.9%) had positive serology for stronglyoides sp. (elisa), and 21 (19.8%) had parasites in stool (including stronglyoides stercoralis in the patient with positive s ... | 1992 | 1558266 |
| a rare case of toxocara canis arachnoidea. | the authors present a case of toxocara canis arachnoidea located in the cervical zone. the rarity of the case and the extreme rarity of the position are emphasized. in fact in medical literature there exists a description of only one similar case which was also observed by one of the authors. | 1992 | 1500961 |
| renal involvement in mice experimentally infected with toxocara canis embryonated eggs. | histological examination of kidneys from mice experimentally infected with toxocara canis embryonated eggs demonstrated the presence of a segmental or diffuse mesangioproliferative glomerulonephritis. immunohistochemical studies established that renal alterations were associated with glomerular deposits of igg, igm and third component of complement (c3). these findings suggest that an immunomediated mechanism might possibly be involved in the genesis of kidney damage observed in mice infected wi ... | 1992 | 1496786 |
| visceral larva migrans in seven members of one family in trinidad. | the occurrence of the first seven cases of visceral larva migrans in trinidad and tobago is described. all cases occurred in children of the same family. the elisa test was used to confirm the clinical diagnosis. | 1992 | 1496701 |
| seroprevalence of toxocara canis antibodies among orang asli (aborigines) in peninsular malaysia. | an enzyme-linked immunosorbent assay using excretory-secretory antigens of the second stage larvae maintained in vitro was used to determine the seroprevalence of toxocara antibodies in orang asli (aborigines) of peninsular malaysia. the mean + 3 sd optical density of 30 healthy subjects was used as the cut-off point. overall prevalence was found to be 31.9%. no significant relationship was found between positive rates with sex and age groups, though children between 0 to 9 years recorded the hi ... | 1992 | 1488706 |
| efficacy of a drug combination of praziquantel, pyrantel embonate, and febantel against helminth infections in dogs. | tablets containing praziquantel, pyrantel embonate, and febantel were tested for efficacy against helminths in dogs. a single treatment with this drug combination gave 100% reductions in toxocara canis and taenia hydatigena in experimentally induced infections in dogs. in dogs with naturally acquired infections, treatment gave > 97 to 98% reductions in fecal egg counts attributable to toxascaris leonina, t canis, and uncinaria stenocephala. efficacy against trichuris vulpis was > 92%. | 1992 | 1476306 |
| seroprevalence of toxocara canis antibodies in humans in northern jordan. | sera of 699 individuals, aged between 5-24 years, from the irbid area, jordan, were tested for toxocara canis antibodies using an elisa-igg test. crude prevalence was 10.9% (76 of 699) but age-adjusted prevalence was 14.3%. the highest prevalence was observed in females aged 5-9 years, 23.3% (7 of 30), and males of 15-19 years of age, 19.5% (16 of 82). the lowest prevalence was observed in females aged 20-25 years, 5.2% (8 of 155). significant differences (p < 0.05) between the prevalences of th ... | 1992 | 1469262 |
| [the helminth fauna of the red fox (vulpes vulpes linne, 1758) in nordhessen and ostwestfalen. 2. nematodes]. | between november 1989 and june 1990 a total number of 397 foxes were examined for the presence of nematodes in the stomach and the small intestine and 403 foxes for the presence of trichinella spiralis larvae. the animals came from the districts of kassel, arnsberg and detmold. in 32.7% of the foxes infections with toxocara canis were found, in 11.1% toxascaris leonina, in 3.8% ancylostoma caninum, in 3.5% uncinaria stenocephala and in 2.3% capillaria species. in most cases the number of nematod ... | 1992 | 1459030 |
| biosynthesis and glycosylation of serine/threonine-rich secreted proteins from toxocara canis larvae. | toxocara canis infective stage larvae continually produce excretory-secretory (tes) glycoproteins in long-term in vitro culture. the kinetics of synthesis and secretion were studied by metabolic labelling with radioactive [35s]methionine, [14c]serine and [14c]threonine. maximal incorporation rates required overnight pre-incubation of parasites in medium depleted of the appropriate amino acid. larvae rapidly incorporated isotope into their somatic tissues, but there was a minimum delay of 10 h be ... | 1992 | 1454427 |
| lectin binding to secretory structures, the cuticle and the surface coat of toxocara canis infective larvae. | toxocara canis infective larvae are known to produce abundant glycosylated molecules which may be found associated with the surface or secreted into their environment. using a range of fluorescein-conjugated and gold-conjugated lectins, the localization of particular carbohydrates was defined on the surface of live parasites, and internally at the ultrastructural level. surface exposure of n-acetyl galactosamine and n-acetyl glucosamine was deduced by binding of fitc-conjugated helix pomatia (hp ... | 1992 | 1454426 |
| [visceral toxocariasis in three children]. | 1992 | 1413796 | |
| [ocular manifestations of selected zoonoses in humans]. | a report is given on the epidemiology and clinical signs of some selected zoonoses that may be of significance for ocular infections in man: brucellosis, leptospirosis, lyme borreliosis, lymphocytic choriomeningitis, newcastle disease, ornithosis (chlamydiosis), rabies, streptococcus suis infection, larva migrans ocularis by toxocara canis or baylisascaris procyonis, toxoplasmosis and tularemia. | 1992 | 1412422 |
| il-4 and ifn (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by th1 or th2 human t cell clones. | the cytolytic potential of a total number of 118 cd4+ human t cell clones specific for purified protein derivative (ppd) from mycobacterium tuberculosis, tetanus toxoid, lolium perenne group i allergen (lol p i), poa pratensis group ix allergen (poa p ix), or toxocara canis excretory/secretory antigen(s) (tes) was assessed by both a lectin (pha)-dependent and a mhc-restricted lytic assay and compared with their profile of cytokine secretion. the majority of clones with th1 or th0 cytokine profil ... | 1992 | 1401925 |
| evaluation of an immunoenzymatic assay detecting specific anti-toxocara immunoglobulin e for diagnosis and posttreatment follow-up of human toxocariasis. | in order to complete the immunodiagnosis of human toxocaral disease, an immunoenzymatic assay with excretory-secretory antigens from toxocara canis larvae was developed for the detection of specific immunoglobulin e (sige enzyme-linked immunosorbent assay [elisa]). the specificity of the assay was evaluated in patients presenting with various allergic or helminthic diseases. the sensitivity was assessed in patients exhibiting clinical and biological symptoms indicative of toxocariasis, serodiagn ... | 1992 | 1400990 |
| oxygen radical scavengers protect against eosinophil-induced injury in isolated perfused rat lungs. | the protective effect of oxygen radical scavengers on lung injury induced by activated eosinophils was examined in isolated perfused rat lungs. eosinophils were obtained by bronchoalveolar lavage from rats infected with toxocara canis and activated with phorbol myristate acetate (pma). there were no changes in pulmonary vascular (rt) and airway (raw) resistances and only minimal changes in vascular permeability assessed using the capillary filtration coefficient (kf,c) in pma control lungs and n ... | 1992 | 1399998 |
| toxocara canis: monoclonal antibodies to carbohydrate epitopes of secreted (tes) antigens localize to different secretion-related structures in infective larvae. | the major secreted glycoproteins of toxocara canis larvae appear to be derived from two specialized organs within the nematode organism. using immunogold electron microscopy, we have analyzed the binding patterns of a panel of monoclonal antibodies (tcn-1 to tcn-8) reactive with toxocara excretory-secretory (tes) antigens. we find, first, that the esophageal gland and lumen are strongly reactive with monoclonals tcn-4, tcn-5, and tcn-8, and because the posterior portion of the gut is closed, we ... | 1992 | 1379195 |
| interrelationship between schistosomiasis and concomitant diseases. | the biological literature contains many examples of mutual influences between different species of parasites, especially with respect to concomitant helminth infections. several situations are known in which the association of infection by schistosoma mansoni with other pathogens in the same host results in a type of disease which differs from the simple summation of the individual effects of each infection. the present study concerns concomitant infections involving s. mansoni and enterobacteri ... | 1992 | 1343911 |
| the significance of the "lung phase" in host-helminth relations. | many helminth infections have a "lung phase" whose significance considering the host-parasite relations has not yet been clarified. in some nematode infections larvae must pass through the lungs, in others adult worms live in the respiratory tract, and some others cause tropical pulmonary eosinophilia. some examples of these infections (nippostrongylus brasiliensis, schistosoma mansoni, trichinella spiralis and toxocara canis) are considered to clarify whether this phase of infection is a "pro-h ... | 1992 | 1339975 |
| development and characterization of a model of eosinophil-mediated cardiomyopathy in rats infected with toxocara canis. | this study begins testing the hypothesis that a causal relationship exists between hypereosinophilia and cardiac dysfunction. rats infected with the nematode toxocara canis develop marked hypereosinophilia, with peak blood eosinophil levels of approximately 3,500 eosinophils/mm3 whole blood observed approximately 14 days postinfection. corresponding to the increase in blood eosinophils of infected animals was a decrease in cardiac performance. by 14 days postinfection, cardiac work had declined ... | 1992 | 1317127 |
| standardization of dot-elisa for the serological diagnosis of toxocariasis and comparison of the assay with elisa. | the dot-enzyme-linked immunosorbent assay (dot-elisa) was standardized using somatic (s) and excretory-secretory (es) antigens of toxocara-canis for the detection of specific antibodies in 22 serum samples from children aged 1 to 15 years, with clinical signs of toxocariasis. fourteen serum samples from apparently normal individuals and 28 sera from patients with other pathologies were used as controls. all samples were used before and after absorption with ascaris suum extract. when the results ... | 1992 | 1307410 |
| [clinical course of symptomatic toxocariasis in a 10-year-old boy]. | a case is described of symptomatic toxocariasis in a boy, with massive invasion of the parasites and strong response of the organism. the course of the disease was very serious. | 1992 | 1295245 |
| nematocidal activity of long alkyl chain amides, amines, and their derivatives on dog roundworm larvae. | the nematocidal activity of amides and amines having a long alkyl chain against the second-stage larva of dog roundworm, toxocara canis, was examined. long chain acyl amides with smaller substituents on the nitrogen showed stronger activity and the activity of cyclic amine amides was stronger than that of acyclic ones. in a series of homologous amides, the activity was dependent on the alkyl chain length: it reached a maximum at an optimal chain length and decreased in both shorter and longer ho ... | 1992 | 1294326 |
| [detection of intestinal parasites from dogs in tochigi-city in 1979 and 1991]. | to clarify whether sanitary and hygienic conditions surrounding humans and pet animals have improved or not, we examined feces from dogs for intestinal parasites in tochigi in 1979 and 1991. intestinal parasites were detected from 109 of the 262 dogs (41.9%) in 1979 and 86 of the 260 dogs (32.8%) in 1991. among the parasites. ancylostoma caninum, tirchuris vulpis and toxocara canis were most commonly detected, and their detection rates were higher in 1979. on the contrary, dipylidium caninum, st ... | 1992 | 1293225 |
| the use of 35s-labelled toxocara canis to determine larval numbers in tissues. | the potential of using 35s-labelled larvae to determine the number of second-stage toxocara canis larvae present in the tissues of infected animals was assessed. infective larvae were labelled by in vitro culture with medium containing 35s-methionine. the amount of radiolabel attached to larvae decayed exponentially with time and had an in vitro mean half life of 3.54 +/- 0.65 days. the 'lost' radiolabel was incorporated into proteins which formed part of the worm's excretory/secretory products. ... | 1992 | 1293195 |
| covert toxocariasis--a cause of recurrent abdominal pain in childhood. | toxocariasis, usually caused by toxocara canis, is a zoonosis acquired by ingestion of worms which inhabit the gut of young canines. domestic pets, such as dogs, become infected from soil in public parks and playgrounds which are often heavily contaminated. although toxocariasis is often regarded as having two principal, though uncommon, manifestations--visceral larva migrans (vlm) and ocular toxocariasis (ot)--recent studies have suggested otherwise. a third, more common, condition, termed 'cov ... | 1992 | 1290741 |
| visceral larva migrans masquerading as liver secondaries. | 1992 | 1287102 | |
| two cases of disseminated toxocariasis in compromised hosts successfully treated with mebendazole. | two cases of disseminated (hepatosplenic, pulmonary and in 1 case also cerebral) toxocariasis in compromised hosts-1 with malignancy (mycosis fungoides) and 1 on chronic corticosteroid treatment due to autoimmune disease--are reported. besides fungi, also other unusual pathogens (of parasitic origin), especially in cancer, shall be considered. | 1992 | 1286579 |
| an investigation of helminth parasites in well-cared for dogs in accra. | a survey of a relative prevalence of helminth parasites in pet dogs has been conducted in the accra metropolitan area. carcass examination revealed a high incidence of ancylostoma caninum (58%), toxocara canis (40%), dipylidium caninum (24%), spirocerca lupi (18%) and a low 2% of taenia pisiformis. stool examination revealed hookworm ova in approximately 39% stools, ascarid ova in 4%, tapeworm in 1.3% and spirocerca in 0.24; a low incidence of strongloides (0.03) and trichurid ova (0.1%) were al ... | 1975 | 1241960 |
| scanning electron microscopy of toxocara canis eggs. | 1975 | 1239072 | |
| contamination of soil in two city parks with canine nematode ova including toxocara canis: a preliminary study. | 1975 | 1237238 | |
| [experimental infection of chickens with the larva of toxocara canis and ascaris suum]. | 1975 | 1216505 | |
| toxocara canis and other nematodes transmitted from dogs to man. | 1975 | 1212601 | |
| [case report on a toxocara-canis infection of the human eye (solitary granuloma) (author's transl)]. | description of one case of an intraocular toxocara-canis infection. it deals with a so-called solitary granuloma at the posterior pole of the eye. an infection with this parasit of world-wide distribution is probably more frequently than commonly supposed. the prognosis of the disease is unfavourable in most cases. the diagnoses of a larva migrans visceralis infection is possible by lamina's microprecipitation-test on the living larva. it is an immune-biological and species specific test. the tr ... | 1975 | 1202260 |
| scanning electron microscopy of the eggs of ascaris lumbricoides, a. suum, toxocara canis, and t. mystax. | eggs of ascaris lumbricoides, a. suum, toxocara canis, and t. mystax were examined by scanning electron microscopy (sem). all species under study exhibited pronounced surface ridges. the ridges formed distinctive patterns in t. canis and t. mystax. in the ascaris species, the ridges are similar except that they are more pronounced in the eggs of a. suum. operculumlike structures were observed only in ascaris. correlation of data from sem with previously reported transmission electron microscopy ... | 1975 | 1185420 |
| [comparative study of the activity and specificity of antigens of toxocara canis and ascaris suum in the indirect hemagglutination reaction]. | 1975 | 1177834 | |
| in vitro maintenance of toxocara canis larvae and a simple method for the production of toxocara es antigen for use in serodiagnostic tests for visceral larva migrans. | 1975 | 1165568 | |
| specificity and sensitivity of skin test reactions to extracts of toxocara canis and ascaris suum. i. skin tests done on infected guinea pigs. | the specificity and sensitivity of adult and larval somatic antigens, and perienteric fluid of toxocara canis and ascaris suum were investigated by using intradermal skin tests in guinea pigs. these animals were infected with low doses (0.01, 0.1 or 1.0 egg/g) of these helminths. toxocara larval antigen (tl) induced larger reactions in toxocara-infected animals than did the other antigens, suggesting a superior sensitivity for this antigen. in addition, ascaris perienteric fluid (ap) provoked sk ... | 1975 | 1155689 |
| dogs and intestinal parasites: a public health problem. | the stools of 239 stray dogs were examined for intestinal parasites. of the helminths found, toxocara canis (43.5%), tapeworms (25.5%), ascaris species (21.3%) and hookworms (12.5%) were the commonest. of the protozoans found, isospora species and entamoeba coli were the most prevalent. an unusual feature of the present study was the finding of ascaris species. the importance of the high prevalence of intestinal parasites in dogs, the close contact of humans with dogs' excreta and the possible r ... | 1975 | 1125888 |
| [tissular reactions in experimental infection of mice by toxocara canis]. | 1975 | 1124327 | |
| experimentally induced cerebrospinal nematodiasis in rabbits (oryctolagus cuniculus). | to determine if the rabbit can act as an intermediate host for ascarids from certain carnivorous animals (skunks, pigs, dogs), 12 rabbits were infected with ascaris columnaris, ascaris suum, or toxocara canis. clinical signs, microscopic lesions, and morphologic features of ascarids with naturally occurring and experimentally induced a columnaris infections were identical. of the 3 induced parasitic infections, a columnaris caused the most severe lesions in the central nervous system (cns). it a ... | 1975 | 1115433 |
| [retinal pseudotumor caused by toxocara canis]. | 1975 | 1110567 | |
| prevalence of toxocara canis and toxascaris leonina ova in dog faeces deposited on the streets of leeds. | 1976 | 1067361 | |
| hepatic and peritoneal invasion by adult ascarids (toxocara canis) in a dog. | 1975 | 1041525 | |
| uredofos: anthelmintic activity against nematodes and cestodes in dogs with naturally occurring infections. | a new broad-spectrum anthelmintic, uredofos, was tested in 146 dogs by single and multiple oral dosing. single doses of 100 and 50 (but not 25) mg/kg were totally effective in removing dipylidium caninum and taenia spp from 46 dogs with infections of tapeworms. among groups of 15 to 20 dogs, the average percentage efficacies against toxocara canis for single soese of 100, 50, and 25 mg/kg were 98, 96, and 81%, respectively. the average percentage of efficacies against hookworm (ancylostoma canin ... | 1976 | 1033721 |
| studies on the infection with the toxocara canis the dog ascarid among egyptians in dakahleia governorate. | 1976 | 1025250 | |
| toxocara canis as a cause of blindness in egyptian children. | 1976 | 1025240 | |
| incidence of toxocara canis and toxocara cati infections among stray dogs and cats in cairo and giza governorates, a.r.e. | 1976 | 1025236 | |
| [prevalence of parasitic diseases by toxocara canis in dogs, and the finding of eggs of toxocara species in the soil of public places in the urban area of londrina, state of parana, brazil]. | 1976 | 1019565 | |
| multiple infection with toxocara canis. influence of antihistamines and corticosteroids on the histopathological response. | the histopathology of the tissues of mice infected with ten doses of 100 embryonated eggs of toxocara canis and the influence of antihistamines and corticosteroids on these findings is described. the main lesions were confined to the liver and lungs. in infected but untreated control mice hepatic lesions consisted of periportal infiltrates, widespread foci of liver cell necrosis and polymorphonuclear and mononuclear accumulation and a few fibrotic granulomata. treatment with antihistamines did n ... | 1976 | 999357 |
| ascaris suum and toxocara canis: egg extract antigens in guinea pigs and the macrophage migration inhibition test. | 1976 | 987922 | |
| helminth parasites of the fox (vulpes vulpes) in new south wales. | a total of 930 foxes (vulpes vulpes) from new south wales were examined for the presence of gastro-intestinal helminth parasites. the cestodes were represented by taenia pisiformis with a prevalence of 15.7%, t. serialis (22.6%), t. taeniaeformis (0.1%), spirometra erinacei (28.7%) and dipylidium caninum (8.3%). no specimens of t. ovis, t. hydatigena or echinococcus granulosus were encountered. toxocara canis was the most prevalent nematode and occurred in 35.2% of foxes. other nematodes encount ... | 1976 | 985241 |
| [intraocular solitary granuloma of toxocara canis (author's transl)]. | 5 cases of intraocular toxocara canis solitary granuloma are demonstrated. the coincidence of two different aspects of a disease: pseudocoloboma of the macula (toxoplasmosis) in the right and a toxocara solitary granuloma in the left eye of the same patient (case 5) perhaps will furnish proof possibility of foetal infection (via placenta) by toxocara canis. | 1976 | 979050 |
| serological and haematological investigations in the course of experimental toxocara canis infections in laboratory mice. | 1976 | 963605 | |
| effect of inoculum size and length of infection on the distribution of toxocara canis larvae in the mouse. | the effect of inoculum size and time on the distribution of toxocara canis larvae in the mouse was investigated by recovering larvae from various body regions 7, 14, 28, and 56 days after administration of either 200, 600 or 1,000 infective eggs to groups of ten male mice. an analysis of variance of larval recoveries from the carcass, liver, brain and cardiopulmonary system suggests that inoculum size was a significant factor determining the proportional recovery for each of these sites. length ... | 1976 | 961975 |
| [worm-diseases]. | intestinal parasites are common among labourers from foreign countries and in immigrants. some worm-infections like ascaridiasis or enterobiasis occur in children quite often even in the cold climates. in cases of ascaridiasis only a heavy infection causes clinical symptoms. the diagnosis is made through the detection of eggs in the stools, as all the other worm-infections are diagnosed from the stool-test. piperazine-derivatives are highly effective against ascaris; another useful drug is pyran ... | 1976 | 955553 |
| toxocara canis: an estimation of the incidence of infection in puppies in an industrial town. | 1976 | 936442 | |
| transplacental migration of toxocara canis larvae in experimentally infected mice. | in experimentally infected, nonpregnant mice the larvae of toxocara canis were not found in the uterus at any time. in mice infected at 1 week, but not at 2 weeks, before gestation, larvae were found in the uterus but not in either the placenta or fetus. in mice infected during pregnancy, larvae were found in the uterus and placenta from the 9th day and in the fetus from the 11th day of pregnancy, more abundantly when infected at the middle than at the earlier stages. examination of microsection ... | 1976 | 932920 |
| the comparison of counterimmunoelectrophoresis with indirect haemagglutination test for detection of antibodies in experimentally infected guinea pigs with toxocara canis. | the humoral response of guinea pigs infected with doses of 500, 1000, and 1500 infective toxocara canis ova were measured by counterimmunoelectrophoresis and indirect haemmagglutination tests one to five weeks after infection. the antigens used in these measurements were prepared from adult t. canis. counterimmunoelectrophoresis showed lower titres than haemagglutination method, but it was performed rapidly and with ease. the possible use of these techniques for immunodiagnosis of human visceral ... | 1977 | 886181 |
| toxocara canis. | 1977 | 878238 | |
| toxocara canis and the disposal of faeces. | 1977 | 860392 | |
| a survey of patent nematode infestations in dogs. | a survey of faecal samples taken from 1000 suburban dogs revealed an infestation of 7-2 per cent toxocara canis, 2-7 per cent toxascaris leonina, 1-3 per cent trichuris vulpis and 1-3 per cent uncinaria stenocephala. the faecal material examined was obtained per rectum from well cared-for pet dogs resident in an area of north-west suburban london. the age of the dogs examined, both male and female, ranged from three weeks to 18 years. the clinical picture of the dogs affected by ascariasis and i ... | 1977 | 860384 |
| larva-specific antibodies in patients with visceral larva migrans. | seven of 10 patients with visceral larva migrans (vlm) had serum precipitating antibodies specific for larval antigens of toxocara canis as determined by double diffusion in agar. such antibodies were absent in 114 normal adults and 25 patients with collagen disease. precipitation of ascarid components by c-reactive protein resulted in false-positive reactions, but this precipitation was readily prevented by appropriate absorption of sera before testing. a more sensitive assay, the enzyme-linked ... | 1977 | 853247 |
| [acute intraocular toxocara canis infection, similar clinical picture of juxtapapillar chorioretinitis (author's transl)]. | a case report is given on acute intraocular toxocara canis infection. a complete clinical development from the beginning of infection until healing without defect is described. therapy was vibramycin (doxycyclin), durenat, prednisolon. | 1977 | 850354 |
| [solitary granuloma in ocular toxocara-canis infection (canine round worm)]. | two cases of toxocara canis infection are reported. they presented a solitary granuloma at the posterior ocular pole. the eyes affected by parasites were practically blind. in the first case the condition was discovered accidentally on a pre-employment examination; in the second case, after a change of doctor - the previous diagnosis was toxoplasmosis. the latter mistake is very common in toxocara infections. our diagnoses were confirmed by lamina's microprecipitation test. for treatment the ant ... | 1977 | 846694 |
| ascariasis and toxocariasis. ii. difficulties in the differential serological diagnosis employing a toxocara canis antigen. | 1976 | 828293 |