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risks of human immunodeficiency virus infection among adolescents attending three diverse clinics.this study was performed to identify specific high-risk behaviors, such as unprotected oral, anal, and vaginal intercourse and substance abuse, associated with human immunodeficiency virus infection among adolescents attending three diverse clinics located in a localized geographic area: a university-based clinic, a planned parenthood clinic, and an inner-city public health clinic (phc). six hundred seventy-one female and 207 male adolescents attending one of the three clinics completed a struct ...19938496769
the pedestrian trauma patient. perspectives from a psychiatric consultation service.the hospital course of adult pedestrians injured by automobiles and treated by a university trauma service over a 12-month period was reviewed to evaluate the prevalence, recognition, and intervention of substance use and suicidal behavior. the study showed that the pedestrian trauma patient had a dramatically high rate of substance use and a surprisingly low index of suspicion of suicide attempt by the treatment team as a cause of the accident. appropriate intervention might greatly reduce the ...19938493303
aquatic biomonitoring of reclaimed water for potable use: the san diego health effects study.highly treated reclaimed wastewater was evaluated as a possible supplement to raw water sources required to meet san diego's growing need for potable water. biomonitoring experiments employing fathead minnows (pimephales promelas) were used to compare reclaimed water with the city's current raw water supply. juvenile fish were exposed in flow-through aquaria in field laboratories located at the reclamation plant (aqua ii) and at a municipal potable water treatment facility (miramar). biomonitori ...19938492326
epidemiology of human immunodeficiency virus type 1 infection among homosexual men participating in hepatitis b vaccine trials in amsterdam, new york city, and san francisco, 1978-1990.homosexual/bisexual men from amsterdam, the netherlands, new york, new york, and san francisco, california, were entered into trials of the efficacy of hepatitis b vaccine shortly before the acquired immunodeficiency syndrome (aids) epidemic was recognized (1978-1980). the authors analyzed data, including serial blood samples tested for antibody to human immunodeficiency virus type 1 (hiv-1) as well as demographic and behavioral information, to characterize the spread of hiv-1 infection within t ...19938484382
pediatric human immunodeficiency virus infection in a low seroprevalence area.although increasing information is available regarding human immunodeficiency virus (hiv) infections of children in high seroprevalence areas, few data are available describing trends in low seroprevalence populations. in san diego county approximately 1 in 1450 live births are to women infected with hiv as identified by nonlinked heel stick testing. seventy-seven hiv-infected children were identified and followed in our clinics during the period 1983 to 1991, of whom 32 (42%) were infected peri ...19938483625
property rights and payment to patients for cell lines derived from human tissues: an economic analysis.the increasing potential for commercial applications in biotechnology has given rise to new legal and ethical questions with regard to ownership of human tissue. as the potential value of human cells and tissue has risen, so have donors' calls for a share in the profits. however, in a recent california ruling (john moore vs the regents of the university of california), the court once again held to its traditional position that individuals do not hold property rights in their own tissue and cells ...19938475423
health practices and disability: some evidence from alameda county.with greater longevity people are increasingly concerned about how to avoid disability during their longer lives. policy decisions concerning ways to extend health as well as life have become part of the nation's health agenda. opportunity to examine that issue has arisen in the alameda county human population laboratory. earlier studies there established seven health practices as risk factors for higher mortality: excessive alcohol consumption, smoking cigarettes, being obese, sleeping fewer or ...19938475014
human immunodeficiency virus type-1 antibody in 6703 institutionalized mentally retarded clients: an unlinked serosurvey at seven california developmental centers.all clients residing in seven california developmental centers were tested for human immunodeficiency virus type 1 (hiv) antibody in an unlinked serosurvey. of 6703 clients, 11 (0.16%) were found positive for hiv-1 antibody by confirmatory western blot and immunofluorescent antibody tests. universal blood and body fluid precautions should be rigorously enforced to prevent institutional spread of hiv even in this low-risk population.19938471315
hiv-1 seroprevalence among women attending sexually transmitted disease clinics in california. california family of surveys and sentinel surveillance consortia.to evaluate the distribution of the human immunodeficiency virus type 1 (hiv-1) epidemic among california women, we analyzed hiv-1 seroprevalence and risk factors among women attending sexually transmitted disease (std) clinics in 21 local health jurisdictions. using standardized protocols developed by the centers for disease control, we tested unlinked serum specimens from women attending participating std clinics in 1989. we analyzed demographic characteristics, hiv risk exposure groups, and r ...19938470383
determination of human t lymphotropic virus type by polymerase chain reaction and correlation with risk factors in northern california blood donors.to determine the relative prevalence of human t lymphotropic virus (htlv) types i and ii, type-specific polymerase chain reaction (pcr) was done on seropositive northern california blood donors. from october 1988 through march 1990, 67 (0.055%) of 122,517 blood donors had confirmed htlv antibody. seropositive donors were more likely to be middle-aged, female, and nonwhite than the overall donor base. pcr of samples from 30 htlv-seropositive donors yielded 19 (63%) with htlv-ii and 9 (30%) with h ...19938450261
a suburban focus of endemic typhus in los angeles county: association with seropositive domestic cats and opossums.thirty-three cases of locally acquired murine typhus were reported in los angeles county residents from may 1984 through february 1988. only eight cases were reported over the previous 20-year period. thirty (91%) cases resided within a suburban area encompassing approximately 50 km2 in northcentral los angeles or had contact with an animal from this area. serologic testing (complement fixation and indirect fluorescent antibody) of selected animals in close association with human cases revealed ...19938447530
prevalence of human immunodeficiency virus infection in a sample of immigrants in the united states.editor's note: years ago, experts predicted that the acquired immunodeficiency syndrome would spread to every part of the world and every part of society. the articles by studemeister and kent and calonge and co-workers(*) that follow are further evidence that this is happening. these and other articles we will publish in the next few months confirm our worst fears and challenge all of us to continue engaging in basic, applied, and behavioral research and to continue providing the very best care ...19938434465
fleas (siphonaptera) infesting giant kangaroo rats (dipodomys ingens) on the elkhorn and carrizo plains, san luis obispo county, california.the giant kangaroo rat, dipodomys ingens (merriam), has a limited distribution in the san joaquin valley, ca. because of reductions in its geographic range, largely resulting from humans, the species was listed as an endangered species in 1980 by the california fish and game commission. as part of a study of the community ecology of southern california endangered species, including d. ingens, we were able to make flea collections from the rats when they were trapped and marked for population stu ...19938433341
mycobacterium bovis infections in san diego: a clinicoepidemiologic study of 73 patients and a historical review of a forgotten pathogen.we have presented 73 patients (48 adults and 25 children) with microbiologically documented m. bovis infections identified over the 12-year period from 1980 through 1991. epidemiologic investigation of these patients revealed that the majority (80%) were of hispanic origin. the non-hispanic patients either had traveled extensively outside the united states, were born in the united states during its endemic period or in other countries with endemic bovine tuberculosis, or were exposed to a close ...19938426535
ectopic pregnancy in the united states: economic consequences and payment source trends.to estimate the annual direct and indirect costs of ectopic pregnancy in the united states and to examine trends in payment source.19938423966
hhs honors nurses on world aids day. 19938422125
outbreaks of salmonella enteritidis gastroenteritis--california, 1993.foodborne infections cause an estimated 6.5 million cases of human illness and 9000 deaths annually in the united states. salmonella is the most commonly reported cause of foodborne outbreaks, accounting for 28% of such outbreaks of known etiology and 45% of outbreak-associated cases during 1973-1987. during 1985-1992, state and territorial health departments reported 437 salmonella enteritidis (se) outbreaks (table 1), which accounted for 15,162 cases of illness, 1734 hospitalizations, and 53 d ...19938413165
duty, truth, and whole human beings. 19938407294
a unique haplotype of the apolipoprotein b-100 allele associated with familial defective apolipoprotein b-100 in a chinese man discovered during a study of the prevalence of this disorder.the prevalence of familial defective apolipoprotein (apo) b-100 (fdb) was determined by sampling 5,160 volunteer subjects from among 14,058 eligible employees of a bank in california. the sample was ethnically diverse (44.6% of the population was non-caucasian). the prevalence of fdb in the study population was 0.08% with a 90% confidence interval of 0.01-0.14%. four subjects were found to have the apob 3500 codon mutation by mutagenic polymerase chain reaction, which creates an mspi site at the ...19938371062
mouse pathogenicity studies of nocardia asteroides complex species and clinical correlation with human isolates.nocardia asteroides complex organisms derived from human specimens between 1979 and 1992 were identified to the species level. of 117 n. asteroides complex organisms, 34 (29%) were n. farcinica, 28 (24%) were n. nova, and 55 (47%) were n. asteroides sensu stricto. an analysis of the specimen sites from which the organisms were derived showed that isolates derived from blood, brain, or bone marrow were more likely to be n. farcinica than the other two species. a study of the virulence of ten stra ...19938354460
exploring norms and beliefs related to aids prevention among california hispanic men.a focus-group study gathered qualitative information from hispanic males in california regarding ethnic factors that might enhance or interfere with aids prevention efforts. a predominantly working-class convenience sample of 75 men aged 18-40 participated in seven groups of 10-12 participants each. three groups were composed of single men, three of married men and one was composed of homosexual and bisexual men. four groups included only participants born outside the united states; and spanish ...19938354375
seroprevalence of human immunodeficiency virus among family practice outpatients.because the human immunodeficiency virus (hiv) is extremely heterogeneous in its impact on various subpopulations, it is important to carry out hiv seroprevalence studies in different subpopulations using standardized techniques. the present study is the first to report seroprevalence rates of hiv in family medicine outpatient populations.19938352037
development of an integrated case management program for vulnerable children.although case management is a recognized technique to organize and coordinate human services, its use with high-risk children is relatively new. this article describes the development of a case management program for children at the center for the vulnerable child at children's hospital, oakland, california, a health care setting that brings together health, social work, and child welfare services. case management was introduced into multidisciplinary clinical programs for foster children, drug- ...19938348846
crack cocaine use and high-risk behaviors among sexually active black adolescents.the recent spread of crack cocaine use among inner-city teenagers has been accompanied by dramatic increases in juvenile delinquency and sexually transmitted diseases (stds) among teenagers. this study examined the prevalence of five factors which promote stds, including human immunodeficiency virus (hiv), among a sample of sexually active black adolescent crack users and non-users from the san francisco bay area. significant differences were observed between these groups with respect to history ...19938347641
human t-lymphotropic virus type i seroprevalence among japanese americans.the epidemiology of human t-lymphotropic virus type i (htlv-i) infection is not well defined in japanese americans. this impairs using approaches that could reduce viral transmission and monitor carriers for the disease. using enzyme-linked immunosorbent assay and p21e recombinant western blot testing, htlv-i antibody was measured in unlinked samples from japanese-american patients at 4 physicians' offices in san francisco, california. of 442 patients, 4 (0.9%; 95% confidence interval 0.25%, 2.3 ...19938342263
emergency department response to domestic violence--california, 1992.a 1993 national poll found that 34% of adults in the united states report having witnessed a man beating his wife or girlfriend and that 14% of women report that a husband or boyfriend has been violent with them (1). studies suggest that as many as 30% of women treated in emergency departments (eds) have injuries or symptoms related to physical abuse (2). a national health objective for the year 2000 is for at least 90% of hospital eds to have protocols for routinely identifying, treating, and r ...19938341235
pitfalls inherent in retrospective time-to-event studies: the example of time to pregnancy.retrospective studies of time from initiation of risk (for example, transfusion of hiv-infected blood) to the occurrence of an endpoint of interest are useful in epidemiology. one example is studies of time to pregnancy, which have evaluated exposures that may affect human fertility. one can reconstruct the non-contracepting interval required for each woman's most recent pregnancy and then treat the data as if the couples had been studied prospectively. as we illustrate, however, failure-time mo ...19938327803
hiv knowledge, communication, and risk behaviors among white, chinese-, and filipino-american adolescents in a high-prevalence aids epicenter: a comparative analysis.we conducted a comparative analysis of human immunodeficiency virus (hiv) knowledge, communication, and risk behaviors among 1272 white, chinese-, and filipino-american 10th and 11th graders in san francisco, california, a high-prevalence aids epicenter. we performed principal components analysis on an epidemiologic survey instrument, and we identified five factors: hiv prevention knowledge, sexual behavior risk index, drug use risk index, hiv misconceptions, and communication about hiv. white s ...19938324499
self-reported sexually transmitted diseases among family planning clients: ethnic differences in sexual risk behavior and hiv risk reduction.the relationship between sexually transmitted diseases (stds) and risk for human immunodeficiency virus (hiv) has been established. little is known, however, about the relationship between being infected with an std and initiating hiv risk-reduction behavior. we interviewed 267 young women who were family planning clients of the san francisco bay-area planned parenthood clinics, of whom 40% were white, 37% african american, and 23% women of other ethnic origins. fifty-three percent of the women ...19938324496
comparison of aids knowledge and hiv-related sexual risk behaviors among adolescents in low and high aids prevalence communities.data were collected from students attending high school in a rural, low acquired immunodeficiency syndrome (aids) prevalence community in northern california, and compared with students in an inner-city aids epicenter (san francisco). the findings demonstrate that rural adolescents have higher levels of human immunodeficiency virus (hiv) knowledge, especially about risk-reduction strategies. however, rural adolescents also report higher rates of hiv-related sexual risk behaviors. rural adolescen ...19938323936
factors associated with multiple sex partners among junior high school students.twenty-one percent of a sample of inner-city junior high school students were found to be sexually active (n = 403). only 31% of them reported a single lifetime sexual partner, 25% reported two partners, and 43% reported three or more partners. logistic regression analysis evaluated the influence of demographic, psychosocial, and behavioral factors on the adolescents' lifetime number of sex partners. respondents whose sexual debut occurred before age 13 years were nine times more likely to repor ...19938323931
diel oviposition periodicity of anopheline mosquitoes (diptera: culicidae) from the americas: anopheles albimanus wieldemann and anopheles freeborni aitken.the diel oviposition patterns of anopheles albimanus and an. freeborni derived from panama and california, u.s.a., respectively, were studied in the laboratory by recording the egg-laying of individuals and colonies at 2-h intervals. anopheles freeborni oviposition patterns were almost exclusively nocturnal, with 80% of eggs being laid during the scotophase. a large, well-defined peak of oviposition, comprising about 70% of eggs laid, occurred 4-6 h before sunrise. anopheles albimanus ovipositio ...19938311576
distribution and molecular analysis of lyme disease spirochetes, borrelia burgdorferi, isolated from ticks throughout california.previous studies describing the occurrence and molecular characteristics of lyme disease spirochetes, borrelia burgdorferi, from california have been restricted primarily to isolates obtained from the north coastal region of this large and ecologically diverse state. our objective was to look for and examine b. burdorferi organisms isolated from ixodes pacificus ticks collected from numerous regions spanning most parts of california where this tick is found. thirty-one isolates of b. burgdorferi ...19938308101
findings from the horizontes acquired immune deficiency syndrome education project: the impact of indigenous outreach workers as change agents for injection drug users.a human immunodeficiency virus (hiv)/acquired immune deficiency syndrome (aids) intervention using indigenous outreach workers was implemented with hispanic injection drug users (idus) and their sexual partners in three locations: laredo, texas; san diego, california; and san juan, puerto rico. a total of 2,169 subjects were contacted, given health education, hiv antibody testing, and follow-up counseling. this article reports on the 1,616 idus (75%) who completed the initial and follow-up inter ...19938307770
a meta-evaluation of nutrition education intervention research among pregnant women.inadequate nutrition during pregnancy retards human fetal growth and increases the risk of delivering a low birthweight (lbw) infant. some studies place particular emphasis on reducing lbw through improved nutrition. consensus documents have strongly recommended intense nutrition education programs for patients at risk. despite this well-defined need few methodologically rigorous studies have been conducted to evaluate the behavioral impact of nutrition education for pregnant patients. criteria ...19938307758
human rabies--texas and california, 1993.during november 1993, two persons, a resident of texas and a visitor to california, died from rabies. this report summarizes epidemiologic and clinical information about these cases.19948302264
ethics in gynecologic surgical innovation.j. marion sims' efforts in surgically curing vesicovaginal fistula are retold. the controversy surrounding his surgical innovation on black slaves is discussed in the context of the ethical principles of autonomy, beneficence, and justice. the relevance of his story to modern surgical innovation in incontinence surgery is emphasized in a discussion of the pereyra, gittes, and paravaginal procedures. a call is made to establish a gynecologic ethic to ensure that patients' rights are respected in ...19948296808
another shakeup at lbl genome center. 19948290951
supporting ethnic and cultural diversity in nursing staff.especially in california, there is a growing need to match the ethnic and cultural profiles of nurses and patients. two bay area healthcare programs pooled financial and human resources to develop long-range strategies aimed at increasing the number of minority graduate nurses. included were a work-study program, a russian immigrant nurse training program and a scholarship program for minority students. a cultural diversity enhancement committee is very active and various educational offerings h ...19948278129
serotypes of salmonella isolated from california turkey flocks and their environment in 1984-89 and comparison with human isolates.serotypes of salmonella from turkeys and their environment identified at the california veterinary diagnostic laboratory system (cvdls) between 1984 and 1989 are reported. between 1988 and 1989, salmonella serotypes from turkeys were compared from two sources: from routine submissions to the cvdls (primarily associated with the national poultry improvement plan), and from a random sample of turkey farms conducted by the national animal health monitoring system (nahms). serotype isolation frequen ...19938257361
risk assessments in the pesticide regulatory process.the risk assessment process offers regulators, registrants, public interest groups and users a means of weighing apparent health effects of pesticides and other chemicals, and measuring their safety for use. this report contains the method for developing relative measures of safety for acute toxicity and expressions of risk for chronic toxicity and assesses-human exposure under a variety of extreme scenarios. since workplace exposures usually exceed environmental exposures by two or more orders ...19938250475
educating school nurses to care for hiv-infected children in school.effects of an educational program on school nurses' knowledge and attitudes about human immunodeficiency virus (hiv) infection in children and changes in practice was investigated. participants (n = 205) attended a one-day workshop held at 11 sites in new jersey. content was clinically focused and derived from a needs assessment of a sample of school nurses throughout new jersey. an adult education format was used, with interactive and affective teaching strategies modeled on the aids training p ...19938246463
initial cross-sectional results from the orinda longitudinal study of myopia.although investigations of human refractive error development and normal ocular growth have been conducted for the last 50 years, no previous study of refractive error and the ocular components has measured all the ocular components.19938233371
chromosome 11q13 amplification in head and neck squamous cell carcinoma.to establish the frequency and clinicopathologic correlates of 11q13 amplification in head and neck squamous cell carcinoma.19938217084
hiv infection in the women's jail, orange county, california, 1985 through 1991.the incidence and prevalence of human immunodeficiency virus (hiv) infection among injection drug users, prostitutes, and other women seeking confidential testing in the orange county women's jail were assessed from 1985 to 1991. a total of 4616 voluntary tests were completed on 3051 women, and 865 women were tested repeatedly. eighty-two women tested positively, a ratio of 1.8 positives per 100 tests or 2.7% of all persons tested. cumulative hiv prevalence increased from 2.5% to 2.7% between 19 ...19938214238
are hiv-infected injection drug users taking hiv tests?knowledge of infection is essential for human immunodeficiency virus-type 1 (hiv-1) treatment initiation and epidemic control. this study evaluates infection knowledge among infected injection drug users and acceptance of confidential testing among injection drug users, particularly those infected with hiv-1.19938214230
human rabies--california, 1994.in january 1994, a 44-year-old california man died from a bat-associated strain of rabies; he had had no known animal bite or other rabies exposure. rabies was not clinically suspected nor confirmed until 1 month after his death. this report summarizes the case investigation.19948208235
potential safety benefits of intelligent cruise control systems.potential safety impact of a hypothetical intelligent cruise control system (iccs) is evaluated in terms of changes in traffic accidents and some traffic operation characteristics affecting safety. the analysis of changes in traffic accidents is accomplished by in-depth examinations of police accident reports for four major counties in california. the evaluation of changes in traffic operation characteristics affecting safety is accomplished by vehicle simulation. the accident analysis reveals t ...19948198682
neuropsychological impairment in human immunodeficiency virus-infection: implications for employment. hnrc group. hiv neurobehavioral research center.individuals infected with the human immunodeficiency virus-type 1 (hiv-1), are at increased risk for neurobehavioral impairment, particularly in later stages of the disease. even patients in the medically asymptomatic or minimally symptomatic stages of infection may show mild deficits on comprehensive neuropsychological (np) test batteries, although the clinical significance of such deficits remains uncertain. the present study used vocational difficulties as markers of clinical significance of ...19948197319
health risks from contaminated water: do class and race matter?the impact of contaminants in water on minorities and economically disadvantaged persons was reviewed. environmental legislation governing water was summarized as background information against which relevant studies were evaluated. the majority of the available information was anecdotal or case study and did not lend itself to making quantitative comparisons or analyses. however, the data did present certain trends that led to the conclusion that inequities concerning exposure to contaminants i ...19938184447
seizures associated with poisoning and drug overdose.a retrospective review of cases consulted by the san francisco bay area regional poison control center during a 2-year period was performed to determine the causes and consequences of seizures associated with poisoning and drug intoxication. of 233 charts coded as involving seizures, 191 occurred in humans and were available for analysis. the leading causes of seizures reported to the poison control center were cyclic antidepressants (55 cases, 29%); cocaine and other stimulants (55 cases, 29%); ...19948179767
sexual risk behavior and condom use among street youth in hollywood.a study of 610 street youth aged 13-23 who attended drop-in centers in hollywood, calif., reveals that 96% are sexually experienced. one-half of the young men and one-third of the young women have engaged in sex for food, money, shelter, drugs or other items needed. twenty-five percent of the men and 15% of the women have injected drugs at some time in their life. some 45% of the men and 30% of the women used condoms at last intercourse. a logistic regression analysis found that among men, those ...19948174692
processed meats and risk of childhood leukemia (california, usa).the relation between the intake of certain food items thought to be precursors or inhibitors of n-nitroso compounds (noc) and risk of leukemia was investigated in a case-control study among children from birth to age 10 years in los angeles county, california (united states). cases were ascertained through a population-based tumor registry from 1980 to 1987. controls were drawn from friends and by random-digit dialing. interviews were obtained from 232 cases and 232 controls. food items of princ ...19948167267
conflicts of interest and the physician's duty to inform. 19948166158
from the centers for disease control and prevention. human plague--united states, 1993-1994. 19948158808
acetylator phenotype, aminobiphenyl-hemoglobin adduct levels, and bladder cancer risk in white, black, and asian men in los angeles, california.there is a large body of epidemiologic and experimental data that have identified a number of arylamines as human bladder carcinogens. metabolic activation is required to biotransform these arylamines into their carcinogenic forms, and n-hydroxylation, which is catalyzed by the hepatic cytochrome p4501a2 isoenzyme, is generally viewed as the first critical step. on the other hand, the n-acetylation reaction, catalyzed by the hepatic n-acetyltransferase enzyme, represents a detoxification pathway ...19948158701
serotypic differentiation of rotaviruses in field samples from diarrheic pigs by using nucleic acid probes specific for porcine vp4 and human and porcine vp7 genes.of 216 fecal and intestinal samples collected from nursing or weaned diarrheic pigs in the united states and canada, 57 were identified as group a rotavirus positive by rna electrophoresis and silver staining. fifty-seven and 52 rotavirus-positive samples were analyzed by hybridization with gottfried and osu pcr-derived gene 9 and 4 probes, respectively. only 17 samples were identified with either homologous vp4 (p)- or vp7 (g)-coding genes or both. one rotavirus identified as g4 and p7 was simi ...19948150940
human plague--united states, 1993-1994.from 1944 through 1993, 362 cases of human plague were reported in the united states; approximately 90% of these occurred in four western states with endemic disease (arizona, california, colorado, and new mexico). during each successive decade of this period, the number of states reporting cases increased from three during 1944-1953 to 13 during 1984-1993 (figure 1), indicating the spread of human plague infection eastward to areas where cases previously had not been reported. in 1993, health d ...19948145715
dr henry garland: the man, the myth, the legend, and the legacy. garland lecture from the 1991 california radiological society meeting.in a century of american radiology, a relatively small number of radiologists have emerged as unquestioned leaders of the specialty. one of those was l. henry garland, late of san francisco, whose multifaceted accomplishments and vigorous personality made him a significant contributor to advances in radiology during 3 decades. the garland family has endowed an annual lecture at the meeting of the california radiological society. this essay is taken from the 1991 lecture, which was an assessment ...19948134586
school-age pregnancy: why hasn't prevention worked?adolescent pregnancy or sexually transmitted disease (std) reduction has not occurred, despite sexuality education and abstinence programs, and intensive publicity and community initiatives. an obstacle to adolescent pregnancy, std, and childbearing prevention is the assumption that adolescent sexuality is a closed system of activity among peers. when a nation is consumed with the preoccupation of condoms versus chastity debates, and is ignoring high poverty levels and abuse of the young, adole ...19938133647
ucsd's medpics: implementation and impact on the curriculum.medpics is a computer-based image delivery system with supporting text fields and on-screen graphics to assist in key feature identification. it has been used by the university of california, san diego as an integral part of the human disease course since 1992. initially created to support pathology and histology, the program has now expanded to include hematology. medpics has had a positive impact on the second year curriculum for which it was created. moreover, use of this program has improved ...19938130582
from the centers for disease control and prevention. human rabies--texas and california, 1993. 19948120949
geographic patterns of disability in the united states.geographic patterns of county prevalence rates of disability benefit receipt are shown for the social security administration's disability insurance (di) and supplemental security income (ssi) programs. prevalence rates were calculated by dividing each county's december 1990 di and ssi disability caseloads by the population aged 18-64 for that year in that county. separate maps were also constructed for men and women recipients. areas with the highest overall di prevalence rates included appalac ...19948091272
would you rather be a 'birth' or a 'genetic' mother? if so, how much?judges face difficult choices when the birth and genetic mothers of a child are separate people who dispute maternal access; the views of the general population may help them. fifty women were asked whether, if they were infertile and could have only one child, they would prefer to be birth mothers (to carry a baby which was not genetically theirs) or genetic mothers (to have another woman carry their genetic baby). similarly, fifty men were asked about their preference for a partner's child. in ...19948083880
potential effect of global warming on mosquito-borne arboviruses.if global warming occurs in california, daily mean temperatures may increase by 3 to 5 degrees c, precipitation patterns will change, and sea level may rise 1 m. studies were done on effect of temperature changes on survival of culex tarsalis coquillett, the primary vector of western equine encephalomyelitis (wee) and st. louis encephalitis (sle) viruses, in two regions where temperatures differed by 5 degrees c. daily mortality of adult vectors increased by 1% for each 1 degree c increase in te ...19948057305
assessment of the reproductive and developmental toxicity of pesticide/fertilizer mixtures based on confirmed pesticide contamination in california and iowa groundwater.pesticides and fertilizers, as used in modern agriculture, contribute to the overall low-level contamination of groundwater sources. in order to determine the potential of pesticide and fertilizer mixtures to produce reproductive or developmental toxicity at concentrations up to 100 x the median level found in groundwater, we prepared and studied two mixtures of pesticides and a fertilizer (ammonium nitrate). one mixture containing aldicarb, atrazine, dibromochloropropane, 1,2-dichloropropane, e ...19948056207
institute of human origins breakup. 19948047875
institute of human origins breakup. 19948047874
ergonomics in the laboratory environment.the focus of this report is how ergonomics--the art of making equipment fit the user--is applied to video display terminal (vdt) use in order to improve productivity. it is recommended that vdt operators be made more comfortable by using ergonomic chairs and tables. the placement of computer screens and keyboards at the workstations should be tailored to the body and its natural motion in order to decrease physical stress.19948044476
incidence of renal anomalies in children prenatally exposed to ethanol.based on a number of studies involving animals as well as human case reports indicating an association between prenatal ethanol exposure and renal malformations, it has been suggested that children with fetal alcohol syndrome (fas) should be screened for renal anomalies. the purpose of this study was to evaluate a group of children prenatally exposed to alcohol to determine the incidence of renal anomalies and to evaluate the need for such a screening procedure.19948036075
implementing the science of unitary human beings at the san diego veterans affairs medical center. 19948028978
from the centers for disease control and prevention. human rabies--california, 1994. 19948028154
immigration and hiv infection: a pilot study.this pilot study was conducted to determine areas in which additional education regarding the human immunodeficiency virus (hiv) is needed by the undocumented and recently immigrated hiv-infected population, and to obtain preliminary information on the ability of this community to access medical treatment for hiv. information regarding health status, immigration status, and the use of medical services was obtained from all hiv-infected undocumented and recently immigrated individuals who sought ...19948024945
institute of human origins: separation issues. 19948016648
institute of human origins: separation issues. 19948016647
pro-life nurses uniting for service.the missouri pro-life nurses claim that nurses have lost the ethical basis of their profession. nurses need to reexamine their attitudes at a time when 1 in 5 physician-members of the american society of internal medicine admits to deliberately helping a patient end his or her life, and when many physicians and nurses favor euthanasia and abortion. former georgia nurse joseph dewey akin was sentenced in october 1992 to life imprisonment for injecting robert price, a quadriplegic, with a lethal d ...19948006780
genotypic analysis of epstein-barr virus isolates associated with nasopharyngeal carcinoma in chinese immigrants to the united states.ebv genotypes of first- and second-generation chinese diagnosed with nasopharyngeal carcinoma in the united states were analyzed by pcr techniques. previous studies showed a geographical distribution of genotypically distinct sub-types of ebv. viruses detected at a higher frequency among chinese npc patients (cf) were distinguished from those found in the majority of caucasian npc patients (df) in the united states by polymorphisms in the bamhi f and i regions. exploiting this distinction, we an ...19947989111
a cluster of tuberculosis among crack house contacts in san mateo county, california.in march 1992, a cluster of 89 persons with tuberculosis infection was identified in san mateo county, california. thirteen persons (15%), including 11 children, were diagnosed with active pulmonary tuberculosis. all contacts were african americans who resided in or visited one of two houses used for crack cocaine smoking or dealing. the patient with the index case, a male infected with human immunodeficiency virus, contributed to the transmission of tuberculosis as a transient resident of sever ...19947977929
changing trends in the epidemiology of human brucellosis in california from 1973 to 1992: a shift toward foodborne transmission.from 1973 through 1992, 426 cases of human brucellosis were reported in california, of which 98% were laboratory confirmed. brucella melitensis was identified in 185 cases (78.7% of the bacteriologically typed cases). hispanics accounted for 81% of the cases from 1983 to 1992 compared with 65% during the previous decade (p < .01). the population-adjusted average annual incidence was higher in hispanics, especially in children and teenagers, compared with non-hispanic whites and african americans ...19947963716
mono-ortho- and non-ortho-substituted polychlorinated biphenyls in human milk from mohawk and control women: effects of maternal factors and previous lactation.fifty-four individual human milk samples from 50 mothers (20 mohawks and 30 controls) were analyzed for four non-ortho- and eight mono-ortho-substituted polychlorinated biphenyls (pcbs). mean total coplanar pcbs concentrations were 49 ng/g and 55 ng/g lipid for mohawk and control women, respectively. a statistical evaluation of all analytical data reveals no significant difference of total coplanar pcb level between mohawk and control women. the level of these contaminants is influenced by the a ...19947944559
adaptability, a key ingredient in life. 19947928543
serological surveillance of plague in dogs and cats, california, 1979-1991.following natural infection both cats and dogs develop antibodies to plague which can be measured for several months after infection. besides being helpful in the diagnosis of plague in domestic carnivores, the antibody titer has important implications in outbreak investigation and surveillance programs. we report the first serological survey for plague in domestic carnivores conducted in california between 1979 and 1991 in five different settings or programs. a total of 4115 dogs and 466 cats w ...19947924244
new bioactive taxoids from cell cultures of taxus baccata.four new taxoids were isolated from cell cultures of taxus baccata. their structures were elucidated by spectroscopic analyses. two were the aglycones corresponding to previously isolated 7-o-xylosides of taxol c [1] and 10-deacetyltaxol c [2]. the third [3] had an n-methylated side-chain, while the fourth, named taxcultine [4], contained an n-propyl group on the side-chain. all four compounds actively promoted tubulin assembly. taxol c [1] showed potent and selective cytotoxicity in the nci hum ...19947908950
machado joseph disease maps to the same region of chromosome 14 as the spinocerebellar ataxia type 3 locus.machado joseph disease (mjd) is an autosomal dominantly inherited neuro-degenerative disorder primarily affecting the motor system. it can be divided into three phenotypes based on the variable combination of a range of clinical symptoms including pyramidal and extra-pyramidal features, cerebellar deficits, and distal muscle atrophy. mjd is thought to be caused by mutation of a single gene which has recently been mapped, using genetic linkage analysis, to a 29 cm region on chromosome 14q24.3-q32 ...19957897622
assessment of exposure to malathion and malaoxon due to aerial application over urban areas of southern california.the state of california conducted aerial applications of malathion (ma) bait over urban areas in the southern california air basin in order to eradicate the mediterranean fruit fly (ceratitis capitata). concern about the potential human health effects of this activity prompted a risk assessment conducted by the california department of health services. estimates of potential human exposures to ma and its primary breakdown product, malaoxon, (mo) are based on assumptions of daily human activities ...19947894269
malathion and malaoxon environmental levels used for exposure assessment and risk characterization of aerial applications to residential areas of southern california, 1989-1990.between august 1989 and july 1990, california conducted a mediterranean fruit fly eradication project in southern california which included repeated aerial applications of malathion bait to urban areas where approximately 1.6 million people resided. concern about the safety of these applications prompted the california department of health services to prepare a risk assessment. the current work presents the estimates of environmental levels of malathion and malaoxon, derived from mass deposition ...19947894268
cocaine and crack use and hiv risk behaviors among high-risk methadone maintenance clients.a discriminant function analysis was performed with data from 409 high-risk heroin addicts at intake into a methadone maintenance treatment program to determine the characteristics of cocaine users. cocaine users presented a higher-risk profile for human immunodeficiency virus (hiv), engaged in a wider variety of criminal activities, were more likely to be african-american, reported more alcohol use, and showed more signs of psychological disturbance. a second discriminant function analysis dete ...19957882869
the spectrum of medical conditions and symptoms before acquired immunodeficiency syndrome in homosexual and bisexual men infected with the human immunodeficiency virus.the full range and occurrence of medical conditions in persons infected with human immunodeficiency virus (hiv) before they develop illnesses that define acquired immunodeficiency syndrome (aids) have not been systematically or completely described. in a retrospective and prospective cohort study, 1,073 homosexual and bisexual men in three us cities were interviewed and examined twice per year from january 1988 to september 1992. study participants were from san francisco, california (273 hiv-se ...19957879784
short report: prevalence of hantavirus infection in rodents associated with two fatal human infections in california.rodents living near two fatal human cases of hantavirus pulmonary syndrome in california were surveyed for evidence of hantavirus infection. seventeen (15%) (14 peromyscus maniculatus and one each of p. truei, eutamias minimus, and microtus californicus) of 114 rodents tested had evidence (enzyme-linked immunosorbent assay or polymerase chain reaction) of hantavirus infection. this suggests that peromyscus mice, and p. maniculatus in particular, may be the reservoir for the virus causing this ne ...19957872450
hiv transmission through donor artificial insemination.to investigate and report cases of human immunodeficiency virus (hiv) transmission through donor artificial insemination (ai) before 1986 at five infertility clinics.19957869555
the impact of a dedicated trauma program on outcome in severely injured patients.in recent years, many trauma centers have been closing or scaling down their operations because of financial losses and lack of commitment by the relevant authorities.19957848094
non-parametric estimation and doubly-censored data: general ideas and applications to aids.in many epidemiologic studies of human immunodeficiency virus (hiv) disease, interest focuses on the distribution of the length of the interval of time between two events. in many such cases, statistical estimation of properties of this distribution is complicated by the fact that observation of the times of both events is subject to intervalcensoring so that the length of time between the events is never observed exactly. following degruttola and lagakos, we call such data doubly-censored. jewe ...19947846412
infection with a babesia-like organism in northern california.human babesiosis is a tick-transmitted zoonosis associated with two protozoa of the family piroplasmorida: babesia microti (in the united states) and b. divergens (in europe). recently, infection with an unusual babesia-like piroplasm (designated wa1) was described in a patient from washington state. we studied four patients in california who were identified as being infected with a similar protozoal parasite. all four patients had undergone splenectomy, three because of trauma and one because o ...19957816065
beyond moore: issues of law and policy impacting human cell and genetic research in the age of biotechnology. 19937779167
california's gas chamber on trial. 19947767049
the reluctance of house staff to perform mouth-to-mouth resuscitation in the inpatient setting: what are the considerations?medical house staff are required to perform cardiopulmonary resuscitation (cpr) as part of their job responsibilities. previously it has been shown that house staff are reluctant to perform mouth-to-mouth resuscitation (mmr) in an out of hospital setting. therefore, whether reluctance to perform mmr extends to the inpatient setting, and, if so, the reasons for this reluctance were investigated.19947740188
case management of substance abusers with hiv disease.case management is a promising intervention that has been used widely in many settings but is not well evaluated with substance abusers. this article describes a case management approach for substance abusers with human immunodeficiency virus (hiv) disease. clients are enrolled from emergency and outpatient clinics of a general hospital. case management focuses on encouraging a substance-free lifestyle, linking clients with needed services, and reducing their risk of transmitting hiv. a research ...19947735090
fda puts the brakes on xenotransplants. 19957732365
cutaneous diseases in human immunodeficiency virus-infected patients referred to the ucla immunosuppression skin clinic: reasons for referral and management of select diseases.many nondermatologist physicians have become skilled at identifying and treating certain human immunodeficiency virus-related skin diseases. they are reserving referrals primarily for diagnostically or therapeutically challenging skin disorders. our purpose was to study the reasons for referral of human immunodeficiency virus-infected patients, and to review the management of select diseases. one-hundred and fifty human immunodeficiency virus-positive outpatients were evaluated consecutively for ...19957729163
is maternal diet worthwhile? 19947728226
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