Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| is reactive dengue ns1antigen test a warning call for hospital admissions? | dengue fever is a major public health problem worldwide. the 2011 revised world health organization (who) guidelines have emphasized on early diagnosis and intervention to reduce the case fatality rate due to dengue fever. rapid diagnostic tests like ns1 antigen assays have improved the detection of cases in early clinical phase of illness but its role as a predictor of severe dengue infection is not very clear. | 2016 | 27190911 |
| factors contributing to increases in prescription drug expenditures borne by national health insurance in south korea. | rapid growth of prescription drug expenditures is a problem in south korea. the objective of this study was to assess the contributions of four variables (therapeutic choice, drug-mix, original use, and price changes) to increases in drug expenditures paid by the national health insurance (nhi) in korea. | 2016 | 27189299 |
| comparison study of clinical outcomes between single-site robotic cholecystectomy and single incision laparoscopic cholecystectomy. | multiport laparoscopic cholecystectomy is the standard surgical procedure for symptomatic gallbladder diseases. the latest evolution is single incision laparoscopic cholecystectomy (silc). single-site robotic cholecystectomy (ssrc) overcomes several limitations of manual silc. the aim of this study is to present our initial experiences in ssrc and to compare its clinical outcomes with those of silc. | 2016 | 27188234 |
| association of cyp8a1 (prostacyclin i2 synthase) polymorphism rs5602 with breast cancer in mexican woman. | breast cancer (bca) is the most common cancer in mexican women. certain risk factors, such as environmental and lifestyle factors have been implicated in bca initiation and progression. moreover, genetic factors, such as single nucleotide polymorphisms (snps) of the p450 system, have been reported in bca. in this report, and for the first time in the literature, we analyzed the rs5602 (67730 t > c) polymorphism in the cyp8a1 in patients with bca and in healthy mexican women to identify a potenti ... | 2016 | 27186408 |
| biodiversity enhances reef fish biomass and resistance to climate change. | fishes are the most diverse group of vertebrates, play key functional roles in aquatic ecosystems, and provide protein for a billion people, especially in the developing world. those functions are compromised by mounting pressures on marine biodiversity and ecosystems. because of its economic and food value, fish biomass production provides an unusually direct link from biodiversity to critical ecosystem services. we used the reef life survey's global database of 4,556 standardized fish surveys ... | 2016 | 27185921 |
| range expansions transition from pulled to pushed waves as growth becomes more cooperative in an experimental microbial population. | range expansions are becoming more frequent due to environmental changes and rare long-distance dispersal, often facilitated by anthropogenic activities. simple models in theoretical ecology explain many emergent properties of range expansions, such as a constant expansion velocity, in terms of organism-level properties such as growth and dispersal rates. testing these quantitative predictions in natural populations is difficult because of large environmental variability. here, we used a control ... | 2016 | 27185918 |
| mirror aneurysms among multiple aneurysms: lesser of the two evils. | to highlight the management nuances in addressing mirror aneurysms (mirans) in a subset of multiple aneurysms. | 2016 | 27185651 |
| synergistic effects of marine reserves and harvest controls on the abundance and catch dynamics of a coral reef fishery. | marine no-take reserves, where fishing and other extractive activities are prohibited, have well-established conservation benefits [1], yet their impacts on fisheries remains contentious [2-4]. for fishery species, reserves are often implemented alongside more conventional harvest strategies, including catch and size limits [2, 5]. however, catch and fish abundances observed post-intervention are often attributed to reserves, without explicitly estimating the potential contribution of concurrent ... | 2016 | 27185553 |
| does pure platelet-rich plasma affect postoperative clinical outcomes after arthroscopic rotator cuff repair? a randomized controlled trial. | the exact role of platelet-rich plasma (prp) in rotator cuff tendon reconstruction remains unclear. | 2016 | 27184542 |
| biotic nitrosation of diclofenac in a soil aquifer system (katari watershed, bolivia). | up till now, the diclofenac (dcf) transformation into its nitrogen-derivatives, n-nitroso-dcf (no-dcf) and 5-nitro-dcf (no2-dcf), has been mainly investigated in wastewater treatment plant under nitrification or denitrification processes. this work reports, for the first time, an additional dcf microbial mediated nitrosation pathway of dcf in soil under strictly anoxic conditions probably involving codenitrification processes and fungal activities. this transformation pathway was investigated by ... | 2016 | 27183461 |
| on the causal links between health indicator, output, combustible renewables and waste consumption, rail transport, and co2 emissions: the case of tunisia. | this study employs the autoregressive distributed lag (ardl) approach and granger causality test to investigate the short- and long-run relationships between health indicator, real gdp, combustible renewables and waste consumption, rail transport, and carbon dioxide (co2) emissions for the case of tunisia, spanning the period of 1990-2011. the empirical findings suggest that the fisher statistic of the wald test confirm the existence of a long-run relationship between the variables. moreover, th ... | 2016 | 27180840 |
| cosmetic appearance of port-site scars 1 year after laparoscopic versus robotic sacrocolpopexy: a supplementary study of the access clinical trial. | to prospectively measure trocar site appearances 1 year after surgery in women participants in the abdominal colpopexy: comparison of endoscopic surgical strategies trial, a 2-center randomized surgical trial (nct01124916). | 2017 | 27180224 |
| the acl graft has different cross-sectional dimensions compared with the native acl: implications for graft impingement. | impingement of anterior cruciate ligament (acl) grafts against the femoral notch and the posterior cruciate ligament (pcl) is thought to be influenced primarily by tunnel position and graft orientation. recent data have implied that the native acl is ribbon-shaped. | 2016 | 27179055 |
| the phospholipase a2 activity of peroxiredoxin 6 modulates nadph oxidase 2 activation via lysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages. | peroxiredoxin 6 (prdx6) is essential for activation of nadph oxidase type 2 (nox2) in pulmonary microvascular endothelial cells (pmvecs), alveolar macrophages (ams), and polymorphonuclear leukocytes. angiotensin ii and phorbol ester increased superoxide/h2o2 generation in pmvecs, ams, and isolated lungs from wild-type (wt) mice, but had much less effect on cells or lungs from prdx6-null or prdx6-d140a-knock-in mice that lack the phospholipase a2 activity (pla2) of prdx6; addition of either lysop ... | 2016 | 27178323 |
| external validation of the practical risk chart for the prediction of delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage. | objective delayed cerebral ischemia (dci) following aneurysmal subarachnoid hemorrhage (asah) occurs in approximately 30% of patients. the practical risk chart was developed to predict dci based on admission characteristics; the authors seek to externally validate and critically appraise this prediction tool. methods a prospective cohort of asah patients was used to externally validate the previously published practical risk chart. the model consists of 4 variables: clinical condition on admissi ... | 2017 | 27177181 |
| estimation of the diffusion constant from intermittent trajectories with variable position uncertainties. | the movement of a particle described by brownian motion is quantified by a single parameter, d, the diffusion constant. the estimation of d from a discrete sequence of noisy observations is a fundamental problem in biological single-particle tracking experiments since it can provide information on the environment and/or the state of the particle itself via the hydrodynamic radius. here, we present a method to estimate d that takes into account several effects that occur in practice, important fo ... | 2016 | 27176323 |
| large-displacement statistics of the rightmost particle of the one-dimensional branching brownian motion. | consider a one-dimensional branching brownian motion and rescale the coordinate and time so that the rates of branching and diffusion are both equal to 1. if x_{1}(t) is the position of the rightmost particle of the branching brownian motion at time t, the empirical velocity c of this rightmost particle is defined as c=x_{1}(t)/t. using the fisher-kolmogorov-petrovsky-piscounov equation, we evaluate the probability distribution p(c,t) of this empirical velocity c in the long-time t limit for c>2 ... | 2016 | 27176286 |
| analysis of selected glutathione s-transferase gene polymorphisms in malaysian type 2 diabetes mellitus patients with and without cardiovascular disease. | type 2 diabetes mellitus (t2dm) is believed to be associated with excessive production of reactive oxygen species. glutathione s-transferase (gst) polymorphisms result in decreased or absent enzyme activity and altered oxidative stress, and have been associated with cardiovascular disease (cvd). the present study assessed the effect of gst polymorphisms on the risk of developing t2dm in individuals of malaysian malay ethnicity. a total of 287 subjects, consisting of 87 t2dm and 64 cvd/t2dm patie ... | 2016 | 27173202 |
| the association of early unexplained elevated alanine aminotransferase with large-for-gestational-age birthweight. | nonalcoholic fatty liver disease causes hepatic insulin resistance and is associated with metabolic syndrome. elevated levels of alanine aminotransferase are associated with nonalcoholic fatty liver disease. the effect of hepatic insulin resistance is not only increased glycogen breakdown but also liberation of free fatty acids due to increased lipolysis. both of these fuel sources are associated with macrosomia. there is little known about the impact of maternal nonalcoholic fatty liver disease ... | 2016 | 27173083 |
| can the fisher-lande process account for birds of paradise and other sexual radiations? | models of the fisher-lande process (flp) have been used successfully to explore many aspects of evolution by sexual selection. despite this success, quantitative tests of these models using data from sexual radiations are rare. consequently, we do not know whether realistic versions of the flp can account for the extent and the rate of evolution of sexually selected traits. to answer this question, we generalize the basic flp model of sexual coevolution and compare predictions of that basic mode ... | 2016 | 27172592 |
| discordant mutations in paired primary and metastatic endometrial adenocarcinomas identified by semiconductor-based sequencing for rapid cancer genotyping. | although endometrial adenocarcinoma is usually treated with surgery, patients with metastatic disease have a poor prognosis. to address the need for better treatment options, molecularly targeted drug therapies are being developed. these targeted therapies rely on accurate mutational profiling of the tumor, which is most often performed on dna from the primary tumor. our objective was to compare mutational concordance in primary tumors with their metastases. we genotyped 11 pairs of primary and ... | 2016 | 27170661 |
| increases in absolute lymphocytes and circulating cd4+ and cd8+ t cells are associated with positive clinical outcome of melanoma patients treated with ipilimumab. | to investigate changes of peripheral blood biomarkers and their impact on clinical outcome following treatment with ipilimumab in advanced melanoma patients. | 2016 | 27169993 |
| comparison effect of azithromycin gel 2% with clindamycin gel 1% in patients with acne. | acne vulgaris is the most common skin disease. local and systemic antimicrobial drugs are used for its treatment. but increasing resistance of propionibacterium acnes to antibiotics has been reported. | 2016 | 27169103 |
| evaluation of heparin anticoagulation protocols in post-renal transplant recipients (ehap-port study). | disturbances in hemostasis are common among renal transplant recipients. because of the risk of thromboembolism and graft loss after transplant, a prophylactic heparin protocol was implemented at st paul's hospital in vancouver, british columbia, in 2011. therapeutic heparin is sometimes prescribed perioperatively for patients with preexisting prothrombotic conditions. there is currently limited literature on the safety and efficacy of heparin use in the early postoperative period. | 2017 | 27168632 |
| an mcmc method for the evaluation of the fisher information matrix for non-linear mixed effect models. | non-linear mixed effect models (nlmems) are widely used for the analysis of longitudinal data. to design these studies, optimal design based on the expected fisher information matrix (fim) can be used instead of performing time-consuming clinical trial simulations. in recent years, estimation algorithms for nlmems have transitioned from linearization toward more exact higher-order methods. optimal design, on the other hand, has mainly relied on first-order (fo) linearization to calculate the fim ... | 2016 | 27166250 |
| longitudinal assessment of mri in hip osteoarthritis using shomri and correlation with clinical progression. | to assess the evolution of mr imaging findings in normal volunteers and subjects with hip osteoarthritis (oa) over 1.5 years described by the semi-quantitative scoring hip oa with mri (shomri) scoring system and their correlation with the evolution of clinical parameters. | 2016 | 27162009 |
| frequency of discordant lesions and false-negative cancers at stereotactic vacuum-assisted biopsy. | this study aimed to determine frequency of discordant lesions and discordant false-negative cancers at stereotactic vacuum-assisted biopsy (svab). | 2016 | 27161209 |
| [effect of metabolic uncontrolled diabetes mellitus (dm) on the resistance index of renal (ir) interlobar arteries assessed with pulsed doppler]. | diabetes mellitus is a chronic degenerative disease characterized by elevated hyperglycemia, triggering a series of processes and culminating in chronic, uncontrolled, cellular and vascular damage in different organs. | 2016 | 27160621 |
| using bundled interventions to reduce surgical site infection after major gynecologic cancer surgery. | to investigate whether implementing a bundle, defined as a set of evidence-based practices performed collectively, can reduce 30-day surgical site infections. | 2016 | 27159744 |
| delayed anterior cruciate ligament reconstruction in young patients with previous anterior tibial spine fractures. | avulsion fractures of the anterior tibial spine in young athletes are injuries similar to anterior cruciate ligament (acl) injuries in adults. sparse data exist on the association between anterior tibial spine fractures (atsfs) and later ligamentous laxity or injuries leading to acl reconstruction. | 2016 | 27159316 |
| descemet-membrane endothelial keratoplasty in patients with retinal comorbidity-a prospective cohort study. | to investigate indications, surgical challenges, and outcome of descemet-membrane endothelial keratoplasty (dmek) in patients with retinal comorbidities (rc). | 2016 | 27158608 |
| evaluation of use of acrylic resin-based surgical guide in the function and quality of life provided by mandibular prostheses with microvascular free fibula flap: a four-year, randomized, controlled trial. | the correct positioning of the microvascular-free fibula flap (mfff) is essential for satisfactory mandibular reconstruction. however, the effect of acrylic resin-based surgical guides on prosthetic rehabilitations has not yet been properly investigated. | 2016 | 27158033 |
| influence of tumor location and other variables on predictive value of intraoperative myogenic motor-evoked potentials in spinal cord tumor surgery. | to study the influence of tumor location (cervical vs. thoracic; extramedullary vs. intramedullary) on predictive value of intraoperative myogenic motor-evoked potentials (imep) changes in patients undergoing surgery for spinal cord tumors. | 2016 | 27157282 |
| three cases of ruptured basilar artery dissection: from diagnosis to endovascular treatment. | ruptured basilar artery dissections are rare, and prognosis is often disastrous. | 2016 | 27155379 |
| interactions of two large antiviral polyamides with the long control region of hpv16. | pa1 and pa25 are large hairpin polyamides that are effective in nearly eliminating hpv16 episomes (dna) in cell culture, and pa25 has broad spectrum activity against three cancer-causing forms of hpv (edwards, t. g., koeller, k. j., slomczynska, u., fok, k., helmus, m., bashkin, j. k., fisher, c., antiviral res. 91 (2011) 177-186). described here are the interactions of these pas with sequences in the long control region (lcr) of hpv16 (7348-122). using an feedta conjugate of pa1 (designed to re ... | 2016 | 27155361 |
| a hybrid gene selection approach for microarray data classification using cellular learning automata and ant colony optimization. | this paper proposes an approach for gene selection in microarray data. the proposed approach consists of a primary filter approach using fisher criterion which reduces the initial genes and hence the search space and time complexity. then, a wrapper approach which is based on cellular learning automata (cla) optimized with ant colony method (aco) is used to find the set of features which improve the classification accuracy. cla is applied due to its capability to learn and model complicated rela ... | 2016 | 27154739 |
| impact of generator replacement on the risk of fidelis lead fracture. | a dilemma arises about the merits of conservative management vs lead replacement and/or extraction when patients with a medtronic sprint fidelis lead undergo generator replacement. conflicting reports suggest that the fracture rate may increase after generator change. | 2016 | 27154229 |
| rna-seq analysis reveals new evidence for inflammation-related changes in aged kidney. | age-related dysregulated inflammation plays an essential role as a major risk factor underlying the pathophysiological aging process. to better understand how inflammatory processes are related to aging at the molecular level, we sequenced the transcriptome of young and aged rat kidney using rna-seq to detect known genes, novel genes, and alternative splicing events that are differentially expressed. by comparing young (6 months of age) and old (25 months of age) rats, we detected 722 up-regulat ... | 2016 | 27153548 |
| performance comparison of fuzzy artmap and lda in qualitative classification of iranian rosa damascena essential oils by an electronic nose. | quality control of essential oils is an important topic in industrial processing of medicinal and aromatic plants. in this paper, the performance of fuzzy adaptive resonant theory map (artmap) and linear discriminant analysis (lda) algorithms are compared in the specific task of quality classification of rosa damascene essential oil samples (one of the most famous and valuable essential oils in the world) using an electronic nose (en) system based on seven metal oxide semiconductor (mos) sensors ... | 2016 | 27153069 |
| ct features of primary graft nonfunction after liver transplantation. | purpose to determine computed tomographic (ct) features of primary graft nonfunction (pnf) after liver transplantation in comparison with those of early graft failure or death by identifiable causes. materials and methods institutional review board approval was obtained and informed consent was waived. among 3947 adult liver transplantations performed in one institution between may 2002 and may 2015, 72 patients died or had graft failure within 10 days, and 38 of them were evaluated with ct. pnf ... | 2016 | 27152552 |
| ultrasound-guided cervical facet joint injections: a viable substitution for fluoroscopy-guided injections? | to evaluate the feasibility of ultrasound (us)-guided cervical facet injections and to identify the potential obstacles to routine use of this technique. | 2016 | 27151905 |
| the ct prevalence of arrested pneumatization of the sphenoid sinus in patients with sickle cell disease. | arrested sphenoid pneumatization is an incidental radiologic finding on ct and mr imaging that may be confused with more aggressive pathologic conditions. no definite etiology for arrested sphenoid pneumatization has been established, though changes in regional blood flow during childhood, as is seen with sickle cell disease, have been proposed. the purpose of our study was to compare the prevalence of arrested pneumatization of the sphenoid sinus in patients with and without sickle cell disease ... | 2016 | 27151749 |
| hyperglycemia and phosphatidylinositol 3-kinase/protein kinase b/mammalian target of rapamycin (pi3k/akt/mtor) inhibitors in phase i trials: incidence, predictive factors, and management. | dysregulation of the phosphatidylinositol 3-kinase/protein kinase b/mammalian target of rapamycin (pi3k/akt/mtor) pathway is implicated in human cancer growth and progression. agents targeting this pathway are associated with hyperglycemia due to interaction with the insulin-glucose regulatory axis. identifying the predictive factors for hyperglycemia in patients treated with these agents may help direct future management. | 2016 | 27151652 |
| aneurysm location as a prognostic outcome factor after subarachnoid hemorrhage from internal carotid artery aneurysms and potential impact for further experimental subarachnoid hemorrhage models. | prognostic factors of favorable and unfavorable clinical outcome after aneurysmal subarachnoid hemorrhage (sah) are still not completely known. we retrospectively analyzed the aneurysm location as a factor for patients' outcome after aneurysmal sah. | 2016 | 27150650 |
| predictors of alcohol and other drug use among pregnant women in a peri-urban south african setting. | alcohol and other drugs (aod) use among pregnant women have been associated with adverse health outcomes for mother and child, during and after pregnancy. factors associated with aod use among women include age, poverty, unemployment, and interpersonal conflict. few studies have looked at demographic, economic, and psychosocial factors as predictors of aod use among pregnant women in low-income, peri-urban settings. the study aimed to determine the association between these risk factors and alco ... | 2016 | 27148402 |
| joint multi-fiber noddi parameter estimation and tractography using the unscented information filter. | tracing white matter fiber bundles is an integral part of analyzing brain connectivity. an accurate estimate of the underlying tissue parameters is also paramount in several neuroscience applications. in this work, we propose to use a joint fiber model estimation and tractography algorithm that uses the noddi (neurite orientation dispersion diffusion imaging) model to estimate fiber orientation dispersion consistently and smoothly along the fiber tracts along with estimating the intracellular an ... | 2016 | 27147956 |
| correlations and neuronal population information. | brain function involves the activity of neuronal populations. much recent effort has been devoted to measuring the activity of neuronal populations in different parts of the brain under various experimental conditions. population activity patterns contain rich structure, yet many studies have focused on measuring pairwise relationships between members of a larger population-termed noise correlations. here we review recent progress in understanding how these correlations affect population informa ... | 2016 | 27145916 |
| risk of surgical site infection varies based on location of disease and segment of colorectal resection for cancer. | current quality-monitoring initiatives do not accurately evaluate surgical site infections based on type of surgical procedure. | 2016 | 27145305 |
| effects of lornoxicam on anastomotic healing: a randomized, blinded, placebo-control experimental study. | introduction and aim. with the implementation of multimodal analgesia regimens, nonsteroidal anti-inflammatory drugs (nsaids) are often administered for optimal pain control and reduction of opioid use. the aim of the study was to examine the effects of lornoxicam, a nsaid, on anastomotic healing employing an animal model. materials and methods. a total of 28 wistar rats were randomly assigned in two groups. all animals underwent ascending colonic transection followed by an end-to-end hand sewn ... | 2016 | 27144224 |
| clinical activity and quality of life indices are valid across ulcerative colitis but not crohn's disease phenotypes. | clinical activity and quality of life (qol) indices assess disease activity in crohn's disease (cd) and ulcerative colitis (uc). however, a paucity of data exists on the validity of these indices according to disease characteristics. | 2016 | 27142671 |
| investigating the usage of point spread functions in point source and microsphere localization. | using a point spread function (psf) to localize a point-like object, such as a fluorescent molecule or microsphere, represents a common task in single molecule microscopy image data analysis. the localization may differ in purpose depending on the application or experiment, but a unifying theme is the importance of being able to closely recover the true location of the point-like object with high accuracy. we present two simulation studies, both relating to the performance of object localization ... | 2016 | 27141148 |
| a symmetric length-aware enrichment test. | young et al., (2010) showed that due to gene length bias the popular fisher exact test should not be used to study the association between a group of differentially expressed (de) genes and a specific gene ontology (go) category. instead they suggest a test where one conditions on the genes in the go category and draws the pseudo de expressed genes according to a length-dependent distribution. the same model was presented in a different context by kazemian et al., (2011) who went on to offer a d ... | 2016 | 27138444 |
| arid1a alteration in aggressive urothelial carcinoma and variants of urothelial carcinoma. | arid1a mutation leads to loss of the products of this tumor-suppressor gene. studies demonstrated arid1a mutation in 20% of stage iv urothelial carcinomas (ucs) with worse prognosis. the expression of arid1a in aggressive variants of uc is not studied properly. from 2000 to 2015, 81 variants of uc (29 micropapillary, 33 sarcomatoid, 31 small cell, 2 nested, and 3 plasmacytoid variants) were identified in the archives of rhode island hospital. immunohistochemistry for anti-arid1a antibody (sigma- ... | 2016 | 27137986 |
| the decision to incision curriculum: teaching preoperative skills and achieving level 1 milestones. | to evaluate the effectiveness of a preoperative skills curriculum, and to assess and document competence in associated obstetrics and gynecology level 1 milestones. | 2017 | 27137663 |
| robust support vector machines for classification with nonconvex and smooth losses. | this letter addresses the robustness problem when learning a large margin classifier in the presence of label noise. in our study, we achieve this purpose by proposing robustified large margin support vector machines. the robustness of the proposed robust support vector classifiers (rsvc), which is interpreted from a weighted viewpoint in this work, is due to the use of nonconvex classification losses. besides the robustness, we also show that the proposed rscv is simultaneously smooth, which ag ... | 2016 | 27137357 |
| comparison of resuscitative protocols for bupropion overdose using lipid emulsion in a swine model. | the aim of this study was to investigate the effects of different treatment combinations on bupropion recovery as well as time to return of spontaneous circulation. | 2016 | 27136657 |
| contraception initiation in the emergency department: a pilot study on providers' knowledge, attitudes, and practices. | almost half of all pregnancies in the united states are unintended; these pregnancies are associated with adverse outcomes. many reproductive-age females seek care in the emergency department (ed), are at risk of pregnancy, and are amenable to contraceptive services in this setting. through a pilot study, we sought to assess ed providers' current practices; attitudes; and knowledge of emergency contraception (ec) and nonemergency contraception (non-ec), as well as barriers with respect to contra ... | 2016 | 27135727 |
| evaluation of dexmedetomidine as an adjuvant to intrathecal bupivacaine in infraumbilical surgeries. | various adjuvants like morphine, buprenorphine and fentanyl, clonidine, ketamine are being used in anaesthetic practice since long for improvement of peri-operative analgesia following spinal anaesthesia. such adjuvants have been helpful in induction of early ambulation but at the cost of their associated adverse effects. therefore search for an effective adjuvant is still going on. currently dexmedetomidine, a highly selective α2-adrenoreceptor agonist is being studied for its adjuvant action i ... | 2016 | 27134975 |
| mandibular access osteotomy for tumor ablation: could a more tissue-preserving technique affect healing outcome? | paramedial mandibulotomy facilitates access for the resection of tumors in the oral and oropharyngeal space; however, severe complications related to surgical techniques and radiotherapy have been reported for this procedure. this study evaluated whether preservation of the periosteum during a mandibulotomy would decrease postoperative complications owing to the increased healing capacity provided by preserving more tissue. | 2016 | 27131029 |
| hypereosinophilia in children and adults: a retrospective comparison. | the differential diagnosis of hypereosinophilia is broad and includes asthma, atopic disease, drug hypersensitivity, parasitic infection, connective tissue disorders, malignancy, and rare hypereosinophilic disorders. hypereosinophilia in children has not been well characterized to date. | 2017 | 27130711 |
| a dry powder combination of pyrazinoic acid and its n-propyl ester for aerosol administration to animals. | combining the advantage of higher efficacy due to local pulmonary administration of pyrazinoic acid (poa) and potent effect of pyrazinoic acid ester (pae) delivered as an aerosol would aid in tuberculosis therapy. a combination spray dried dry powder, composed of poa, pae (n-propyl poa), maltodextrin and leucine, was prepared for aerosol delivery to animals. solid-state characteristics of morphology (scanning electron microscopy) crystallinity (x-ray powder diffraction), thermal properties (ther ... | 2016 | 27130363 |
| effect of race/ethnicity on clinical presentation and risk of gestational trophoblastic neoplasia in patients with complete and partial molar pregnancy at a tertiary care referral center. | the reported incidence of molar pregnancy varies widely among different geographic locations. this variation has been attributed, at least in part, to racial/ethnic differences. while the incidence of molar pregnancies is decreasing, certain ethnic groups such as hispanics, asians, and american indians continue to have an increased risk of developing gestational trophoblastic disease across the globe. | 2016 | 27130239 |
| the comparative role of the anterior cruciate ligament and anterolateral structures in controlling passive internal rotation of the knee: a biomechanical study. | to determine the respective functions of the anterior cruciate ligament (acl) and the anterolateral structures (alss) in controlling the tibia's passive internal rotation (ir) with respect to the femur, under uniaxial rotation. | 2016 | 27129374 |
| robust feature selection from microarray data based on cooperative game theory and qualitative mutual information. | high dimensionality of microarray data sets may lead to low efficiency and overfitting. in this paper, a multiphase cooperative game theoretic feature selection approach is proposed for microarray data classification. in the first phase, due to high dimension of microarray data sets, the features are reduced using one of the two filter-based feature selection methods, namely, mutual information and fisher ratio. in the second phase, shapley index is used to evaluate the power of each feature. th ... | 2016 | 27127506 |
| gender difference in the response to valsartan/amlodipine single-pill combination in essential hypertension (china status ii): an observational study. | the china status ii is a prospective, multicentre, open-label, post-marketing, observational study including chinese adults (aged ⩾ 18 years) with essential hypertension who were prescribed once-daily valsartan/amlodipine (val/aml 80/5 mg) single-pill combination. in order to examine gender differences in treatment response to val/aml, we further analysed data from the china status ii study. | 2017 | 27127102 |
| investigation of personality traits between infertile women submitted to assisted reproductive technology or surrogacy. | personality traits affect human relationships, social interactions, treatment procedures, and essentially all human activities. the purpose of this study is to investigate the personality traitsincluding sensation seeking, flexibility, and happiness among a variety of infertile women who were apt to choose assisted reproductive technology (art) or surrogacy. | 2017 | 27123206 |
| the prevalence of intraspinal anomalies in infantile and juvenile patients with "presumed idiopathic" scoliosis: a mri-based analysis of 504 patients. | though several studies have reported the incidence of intraspinal neural axis abnormalities in infantile and juvenile "presumed idiopathic" scoliosis, there has been a varying prevalence ranging from 11.1 to 26.0% based on a limited sample size. therefore, such inconclusive findings have resulted in some questions on the mri-associated role in the management of these patients. we aimed to investigate the prevalence and distribution of intraspinal anomalies in the infantile and juvenile patients ... | 2016 | 27121616 |
| implementation and validation of statistical tests in research's software helping data collection and protocols analysis in surgery. | the use of information technology is often applied in healthcare. with regard to scientific research, the sinpe(c) - integrated electronic protocols was created as a tool to support researchers, offering clinical data standardization. by the time, sinpe(c) lacked statistical tests obtained by automatic analysis. | 2016 | 27120732 |
| exploring self-use, attitude and interest to study complementary and alternative medicine (cam) among final year undergraduate medical, pharmacy and nursing students in sierra leone: a comparative study. | cam inclusion into the curricula of health training institutions, a strategy for its integration into the main stream healthcare delivery system is growing globally. future healthcare professionals knowledge and perception of cam are key determinants to its successful integration. thus, the main objective of this study was to compare the use, attitude and interest to study cam among final year undergraduate medical, pharmacy and nursing students at the college of medicine and allied health scien ... | 2016 | 27118576 |
| cellular profile and expression of immunologic markers in chronic apical periodontitis from hiv-infected patients undergoing highly active antiretroviral therapy. | this study tested the hypothesis that the inflammatory cell profile (cd3-, cd4-, cd8-, cd20-, and cd68-positive cells) and the expression of immunologic markers (tumor necrosis factor α, interferon-γ, interleukin-6, and interleukin-18) in chronic apical periodontitis are the same between non-hiv-infected patients and hiv-infected patients undergoing highly active antiretroviral therapy (haart). | 2016 | 27118467 |
| acanthamoeba keratitis among rigid gas permeable contact lens wearers in the united states, 2005 through 2011. | to describe the clinical presentation and outcomes of acanthamoeba keratitis (ak) in rigid gas permeable (rgp) contact lens wearers and to identify modifiable risk factors. | 2016 | 27117780 |
| [establishment and evaluation of a prognostic model for acute pulmonary embolism]. | to identify the factors influencing the prognosis of patients with acute pulmonary embolism(pe) and to establish a prognostic model. | 2016 | 27117077 |
| educational value of digital whole slides accompanying published online pathology journal articles: a multi-institutional study. | -despite great interest in using whole slide imaging (wsi) in pathology practice and education, few pathology journals have published wsi pertinent to articles within their pages or as supplemental materials. | 2016 | 27116087 |
| noninfectious vitritis after intravitreal injection of anti-vegf agents: variations in rates and presentation by medication. | the purpose of this study was to describe and compare the rates and characteristics of noninfectious vitritis after intravitreal injection of bevacizumab (avastin, genentech, south san francisco, ca), ranibizumab (lucentis, genentech), and aflibercept (eylea, regeneron, tarrytown, ny). | 2016 | 27115856 |
| information functional theory: electronic properties as functionals of information for atoms and molecules. | how to accurately predict electronic properties of a columbic system with the electron density obtained from experiments such as x-ray crystallography is still an unresolved problem. the information-theoretic approach recently developed in the framework of density functional reactivity theory is one of the efforts to address the issue. in this work, using 27 atoms and 41 molecules as illustrative examples, we present a study to demonstrate that one is able to satisfactorily describe such electro ... | 2016 | 27115776 |
| modified supraorbital keyhole approach to anterior circulation aneurysms. | to select a surgical approach for aneurysm clipping by comparing 2 approaches. | 2016 | 27114960 |
| efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study. | the purpose of this study was to investigate postoperative analgesic effect of ropivacaine administered as main or supplemental injection for the inferior alveolar nerve block (ianb) in patients undergoing lower third molar surgery. | 2017 | 27114091 |
| the hijdra scale has significant prognostic value for the functional outcome of fisher grade 3 patients with subarachnoid hemorrhage. | despite its high prevalence among patients with aneurysmal subarachnoid hemorrhage (asah) and high risk of delayed cerebral ischemia (dci), the fisher grade 3 category remains a poorly studied subgroup. the aim of this cohort study has been to investigate the prognostic value of the hijdra sum scoring system for the functional outcome in patients with fisher grade 3 asah, in order to improve the risk stratification within this fisher category. | 2016 | 27113903 |
| [factors associated with anastomotic leak following anterior resection for rectal cancer]. | to explore the related factors of anastomotic leakfollowing anterior resection for the rectal cancer and the association of the preoperative nutritional risk screening 2002(nrs2002) score. | 2016 | 27112476 |
| the effect of a newly designed needle on the pain and bleeding of patients during oocyte retrieval of a single follicle. | the purpose of this study was to evaluate the effect of needle type on pain and bleeding during oocyte pick-up (opu). | 2017 | 27110519 |
| effect of immunosuppressive therapy on cardiovascular risk factor prevalence in kidney-transplanted children: comparative study. | cardiovascular disease (cvd) is the second major cause of death in kidney-transplanted children. cardiovascular risk factors (cvrf) prevalence after transplant may increase. the effect of immunosuppressive therapy has not been fully studied in children. the objective of the study was to measure and compare cvrf prevalence in kidney-transplanted children, depending of immunosuppressive therapy. | 2016 | 27110020 |
| cyp3a5 genotype and time to reach tacrolimus therapeutic levels in renal transplant children. | cyp3a5 gene polymorphism rs776746 has been associated with lower tacrolimus dose requirements and bioavailability in both adults and children. this variant causes a loss of cyp3a5 activity owing to a splice site variant leading to a truncated inactive enzyme. the aim of this study was to determine if the rs776746 gene polymorphism is related to the time to reach tacrolimus therapeutic levels in renal transplant children. | 2016 | 27110018 |
| impact of immunoglobulin therapy in intestinal transplant recipients with posttransplantation hypogammaglobulinemia. | severe hypogammaglobulinemia (hgg) (igg <400 mg/dl) following intestinal transplantation is common. although igg replacement therapy is commonly used, clinical outcomes associated with increasing igg levels to >400 mg/dl are not well described. | 2016 | 27109982 |
| [avoidable hospital admissions for heart failure, spain]. | the avoidable hospital admissions for heart failure are a problem for health systems worldwide, as they waste resources, generate additional morbidities and high mortality. the objective of this study was to determine the risk factors in patients hospitalized for heart failure. | 2016 | 27109838 |
| a case of hyperacute onset of vasospasm after aneurysmal subarachnoid hemorrhage and refractory vasospasm treated with intravenous and intraventricular nitric oxide: a mini review. | a case of hyperacute vasospasm, indicating a poor prognosis after aneurysmal subarachnoid hemorrhage (sah), is reported, and a review is presented of the literature addressing use of nitric oxide (no) donors in cases of refractory vasospasm and recurrent delayed cortical ischemias (dci). | 2016 | 27109628 |
| onyx embolization for tentorial dural arteriovenous fistula with pial arterial supply: case series and analysis of complications. | we describe treatment with onyx embolization in a series of cases of tentorial dural arteriovenous fistula (davf) with pial arterial supply. the aim of this study was to analyze the cause of intraoperative hemorrhage and to explore therapeutic strategies. | 2016 | 27108795 |
| effect of spontaneous activity on stimulus detection in a simple neuronal model. | it is studied what level of a continuous-valued signal is optimally estimable on the basis of first-spike latency neuronal data. when a spontaneous neuronal activity is present, the first spike after the stimulus onset may be caused either by the stimulus itself, or it may be a result of the prevailing spontaneous activity. under certain regularity conditions, fisher information is the inverse of the variance of the best estimator. it can be considered as a function of the signal intensity and t ... | 2016 | 27106186 |
| an investigation of multidimensional voice program parameters in three different databases for voice pathology detection and classification. | automatic voice-pathology detection and classification systems may help clinicians to detect the existence of any voice pathologies and the type of pathology from which patients suffer in the early stages. the main aim of this paper is to investigate multidimensional voice program (mdvp) parameters to automatically detect and classify the voice pathologies in multiple databases, and then to find out which parameters performed well in these two processes. | 2017 | 27105857 |
| an informational transition in conditioned markov chains: applied to genetics and evolution. | in this work we assume that we have some knowledge about the state of a population at two known times, when the dynamics is governed by a markov chain such as a wright-fisher model. such knowledge could be obtained, for example, from observations made on ancient and contemporary dna, or during laboratory experiments involving long term evolution. a natural assumption is that the behaviour of the population, between observations, is related to (or constrained by) what was actually observed. the p ... | 2016 | 27105672 |
| the evolution of sex-specific dominance in response to sexually antagonistic selection. | arguments about the evolutionary modification of genetic dominance have a long history in genetics, dating back more than 100 years. mathematical investigations have shown that modifiers of the level of dominance at the locus of interest can spread at a reasonable rate only if heterozygotes at that locus are common. one hitherto neglected scenario is that of sexually antagonistic selection, which not only is ubiquitous in sexual species but also can generate stable high frequencies of heterozygo ... | 2016 | 27104997 |
| discovery of clinically approved agents that promote suppression of cystic fibrosis transmembrane conductance regulator nonsense mutations. | premature termination codons (ptcs) in the cystic fibrosis transmembrane conductance regulator (cftr) gene cause cystic fibrosis (cf). several agents are known to suppress ptcs but are poorly efficacious or toxic. | 2016 | 27104944 |
| in vitro analysis of the fracture resistance of cad-cam monolithic zirconia molar crowns with different occlusal thickness. | to compare the fracture resistance and mode of failure of cad-cam monolithic zirconia crowns with different occlusal thickness. | 2016 | 27104931 |
| method modification study for the thermo scientific suretect™ listeria species assay-matrix extension. | the thermo scientific™ suretect™ listeria species assay is a new real-time pcr assay for the detection of all species of listeria in food and environmental samples. the assay was originally certified as performance tested methods(sm) (ptm) 071304 in 2013. this report details the method modification study undertaken to extend the performance claims of the assay for matrixes of raw ground turkey, raw ground pork, bagged lettuce, raw pork sausages, pasteurized 2% fat milk, raw cod, pasteurized brie ... | 2017 | 27103105 |
| association of automatically quantified total blood volume after aneurysmal subarachnoid hemorrhage with delayed cerebral ischemia. | the total amount of extravasated blood after aneurysmal subarachnoid hemorrhage, assessed with semiquantitative methods such as the modified fisher and hijdra scales, is known to be a predictor of delayed cerebral ischemia. however, prediction rates of delayed cerebral ischemia are moderate, which may be caused by the rough and observer-dependent blood volume estimation used in the prediction models. we therefore assessed the association between automatically quantified total blood volume on ncc ... | 2016 | 27102313 |
| impact of violated high-dose refuge assumptions on evolution of bt resistance. | transgenic crops expressing bacillus thuringiensis (bt) toxins have been widely and successfully deployed for the control of target pests, while allowing a substantial reduction in insecticide use. the evolution of resistance (a heritable decrease in susceptibility to bt toxins) can pose a threat to sustained control of target pests, but a high-dose refuge (hdr) management strategy has been key to delaying countervailing evolution of bt resistance. the hdr strategy relies on the mating frequency ... | 2016 | 27099624 |
| cleft lip repair: the hybrid subunit method. | the unilateral cleft lip repair is one of the most rewarding and challenging of plastic surgery procedures. surgeons have introduced a variety of straight line, geometric, and rotation-advancement designs, while in practice the majority of north american surgeons have been using hybrids of the rotation-advancement techniques. the anatomic subunit approach was introduced in 2005 by fisher and has gained popularity, with early adopters of the design touting its simplicity and effectiveness. the ob ... | 2016 | 27097136 |
| [etiology study on severe cases caused by hand-foot-mouth disease in children from henan province, 2014]. | to investigate the etiology of severe hand-foot-mouth disease (hfmd) in children in henan province. | 2016 | 27087228 |
| effects of different cusp coverage restorations on the fracture resistance of endodontically treated maxillary premolars. | cusp coverage restorations for the restoration of endodontically treated teeth represent a conservative approach in terms of function and esthetics. however, limited scientific data are available regarding the optimum reduction design and thicknesses. | 2016 | 27086106 |
| evaluation of a metal artifact reduction algorithm applied to post-interventional flat detector ct in comparison to pre-treatment ct in patients with acute subarachnoid haemorrhage. | metal artefacts can impair accurate diagnosis of haemorrhage using flat detector ct (fd-ct), especially after aneurysm coiling. within this work we evaluate a prototype metal artefact reduction algorithm by comparison of the artefact-reduced and the non-artefact-reduced fd-ct images to pre-treatment fd-ct and multi-slice ct images. | 2017 | 27085699 |
| five-year follow-up study of monarc transobturator tape for surgical treatment of primary stress urinary incontinence. | we hypothesized that transobturator tape (tot) is safe and efficacious for the treatment of urodynamic stress incontinence in the long term. | 2016 | 27085545 |