Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| bacterial contamination of anterior chamber during iol surgery. | to study the nature and frequency of bacterial contamination during cataract surgery. | 1999 | 10858775 |
| crystal structure of cambialistic superoxide dismutase from porphyromonas gingivalis. | the crystal structure of cambialistic superoxide dismutase (sod) from porphyromonas gingivalis, which exhibits full activity with either fe or mn at the active site, has been determined at 1.8-a resolution by molecular replacement and refined to a crystallographic r factor of 17.9% (rfree 22.3%). the crystals belong to the space group p212121 (a = 75.5 a, b = 102.7 a, c = 99.6 a) with four identical subunits in the asymmetric unit. each pair of subunits forms a compact dimer, but not a tetramer, ... | 2000 | 10848964 |
| corneal biopsy in the management of progressive microbial keratitis. | to study the indications and role of diagnostic corneal biopsy in the management of patients with progressive microbial keratitis. | 2000 | 10844046 |
| autolysis and related proteolysis in swiss cheese for two lactobacillus helveticus strains. | intracellular peptidases of lactobacillus helveticus may play a major role in the proteolysis of swiss cheeses, provided that they are released through bacterial lysis. experimental swiss cheeses were manufactured on a small scale from thermized and microfiltered milk using as starters (in addition to streptococcus thermophilus and propionibacterium freudenreichii) one of two lb. helveticus strains, itglh1 and itglh77, which undergo lysis to different extents in vitro. all the cheeses were bioch ... | 2000 | 10840680 |
| structural interpretations of f(0) rotary function in the escherichia coli f(1)f(0) atp synthase. | f(1)f(0) atp synthases are known to synthesize atp by rotary catalysis in the f(1) sector of the enzyme. proton translocation through the f(0) membrane sector is now proposed to drive rotation of an oligomer of c subunits, which in turn drives rotation of subunit gamma in f(1). the primary emphasis of this review will be on recent work from our laboratory on the structural organization of f(0), which proves to be consistent with the concept of a c(12) oligomeric rotor. from the nmr structure of ... | 2000 | 10838053 |
| operation of the f(0) motor of the atp synthase. | atp, the universal carrier of cell energy is manufactured from adp and phosphate by the enzyme atp synthase using the energy stored in a transmembrane ion gradient. the two components of the ion gradient (deltaph or deltapna(+)) and the electrical potential difference deltapsi are thermodynamically but not kinetically equivalent. in contrast to accepted wisdom, the electrical component is kinetically indispensable not only for bacterial atp synthases but also for that from chloroplasts. recent b ... | 2000 | 10838052 |
| granulomatous hepatitis in an immunocompromised patient diagnosed by minilaparoscopy. | 2000 | 10817195 | |
| the cutaneous microflora of adolescent, persistent and late-onset acne patients does not differ. | the cutaneous microbiology and antibody status to propionibacterium acnes of patients with persistent (males, n = 32; females, n = 33) and late-onset (females, n = 25) acne were compared with individuals with adolescent acne (males, n = 22; females, n = 18) and normal control volunteers (persistent acne: males, n = 26; females, n = 30; late-onset: females, n = 20). males had significantly higher grades of acne compared with females (p < 0.05). the microflora consisted in the main of propionibact ... | 2000 | 10809844 |
| phototherapy and acne vulgaris. | 2000 | 10809839 | |
| pathophysiological roles of interleukin-18 in inflammatory liver diseases. | innate immune response to microbes sometimes determines the nature of the following specific immune response. kupffer cells, a potent constituent of innate immunity, play a key role in developing the type 1 immune response by interleukin (il)-12 production. furthermore, kupffer cells have the potential to induce liver injury by production of il-18. propionibacterium acnes-primed lipopolysaccharide (lps)-challenged liver injury is the prototype of il-18-induced tissue injury, in which il-18 acts ... | 2000 | 10807517 |
| cytokine regulation of liver injury and repair. | by comparing the hepatic responses to tumor necrosis factor (tnf)-alpha that occur during situations that promote liver injury (such as obesity or chronic exposure to ethanol) with those that occur after stimuli (such as partial hepatectomy) that lead to liver regeneration, it is apparent that hepatocytes are usually able to constrain noxious responses to tnf-alpha, such as the release of reactive oxygen from mitochondria. it appears that by promptly upregulating survival genes that regulate mit ... | 2000 | 10807515 |
| liver-infiltrating t lymphocytes are attracted selectively by ifn-inducible protein-10. | we have demonstrated that interferon-inducible protein-10 (ip-10) is produced in hepatocytes surrounded by infiltrative mononuclear cells in chronic hepatitis. to clarify the role of ip-10 in hepatitis, we examined the chemoattractive activity of ip-10 on liver-infiltrating lymphocytes in experimental animal models of hepatitis. ip-10 was specifically induced in the livers of mice treated intravenously (i.v.) with con a, while monocyte chemotactic protein-1 (mcp-1) showed a much lower level of i ... | 2000 | 10805209 |
| propionic acid fermentation of glycerol and glucose by propionibacterium acidipropionici and propionibacterium freudenreichii ssp. shermanii. | a comparative study was carried out in anaerobic batch cultures on 20 g/l of either glycerol or glucose using two propionibacteria strains, propionibacterium acidipropionici and propionibacterium freudenreichii ssp. shermanii. in all cases, fermentation end-products were the same and consisted of propionic acid as the major product, acetic acid as the main by-product and two minor metabolites, n-propanol and succinic acid. evidence was provided that greater production of propionic acid by propio ... | 2000 | 10803900 |
| effects of 50 hz electric currents and magnetic fields on the prokaryote propionibacterium acnes. | the effects of 50 hz sinusoidal electric currents and magnetic fields on the gram-positive skin bacterium propionibacterium acnes were investigated. intracellular free calcium ([ca(2+)](i)), intracellular ph (ph(i)), and cell viability were examined, based on their relevance to elf field studies and on previous studies conducted on p. acnes (uva irradiation, photosensitization using porphyrin-based sensitizers, and broad-band red light). the [ca(2+)](i) and the ph(i) were measured spectrofluorim ... | 2000 | 10797458 |
| isolation and characterization of proline iminopeptidase from propionibacterium freudenreichii atcc 9614. | a dimeric, 90 kda subunit intracellular proline iminopeptidase from propionibacterium freudenreichii atcc 9614 was purified to homogeneity by chromatography on hydroxyapatite, sephacryl 200, phenyl superose and mono q. the enzyme was specific on pro-p-nitroanilide and pro-x dipeptides. it hydrolyzed 2 fragments of hormone oligopeptides with an n-terminal proline: bradykinin, f2-7 and substance p, f4-11. a number of oligopeptides containing 5-11 amino acids residues and proline at the penultimate ... | 2000 | 10795576 |
| biochemical properties of streptococcus macedonicus strains isolated from greek kasseri cheese. | a total of 32 streptococcus macedonicus strains, isolated from greek kasseri cheese, were screened for biochemical properties of technological importance in milk fermentation processing, such as acid production, proteolytic and lipolytic activity, citrate metabolism, exopolysaccharide production, antimicrobial activity and biogenic amines production. all strains were found to be moderate acidifiers in milk. only four strains could hydrolyse milk casein, while 11 strains showed lipolytic activity ... | 2000 | 10792542 |
| interactions between pyruvate and lactate metabolism in propionibacterium freudenreichii subsp. shermanii: in vivo (13)c nuclear magnetic resonance studies. | in vivo (13)c nuclear magnetic resonance spectroscopy was used to elucidate the pathways and the regulation of pyruvate metabolism and pyruvate-lactate cometabolism noninvasively in living-cell suspensions of propionibacterium freudenreichii subsp. shermanii. the most important result of this work concerns the modification of fluxes of pyruvate metabolism induced by the presence of lactate. pyruvate was temporarily converted to lactate and alanine; the flux to acetate synthesis was maintained, b ... | 2000 | 10788375 |
| ability of lactobacillus and propionibacterium strains to remove aflatoxin b, from the chicken duodenum. | the ability of lactobacillus rhamnosus strains gg and lc-705 to remove afb1 from the intestinal luminal liquid medium has been tested in vivo using a chicken intestinal loop technique. in this study, the gg strain of l. rhamnosus decreased afb1 concentration by 54% in the soluble fraction of the luminal fluid within 1 min. this strain was more efficient in binding afb1 compared with l. rhamnosus strain lc-705 (p < 0.05) that removed 44% of afbl under similar conditions. accumulation of afb1 into ... | 2000 | 10772225 |
| delayed onset of generalized tonic-clonic seizures as a complication of halo orthosis. case report. | the authors report on the case of a 29-year-old man who presented with new-onset, generalized tonic-clonic seizures 11 years after being treated with a halo orthosis for a neurologically intact c-7 fracture. neuroimaging and surgical findings indicated that the epileptic focus was scar tissue, which developed secondary to halo pin penetration of the skull. this complication of halo orthosis has not yet been reported in the literature. | 2000 | 10763700 |
| the change in leukotrienes and lipoxins in activated mouse peritoneal macrophages. | the aim of this study was to investigate to what extent the generation of leukotrienes (lts) and lipoxins (lxs) was affected by the expression of definite levels of macrophage activation. we used a system of murine peritoneal macrophages at different states of activation consisting in resident macrophages and fcs-, thioglycollate- or corynebacterium parvum-elicited macrophages. the profile of lipoxygenase metabolites in resident macrophages was characterized by the presence of high levels of 12- ... | 2000 | 10760459 |
| preliminary characterization of bacteriocins produced by enterococcus faecium and enterococcus faecalis isolated from pig faeces. | a total of 92 enterococci, isolated from the faeces of minipigs subjected to an in vivo feeding trial, were screened for the production of antimicrobial substances. bacteriocin production was confirmed for seven strains, of which four were identified as enterococcus faecalis and three as enterococcus faecium, on the basis of physiological and biochemical characteristics. the bacteriocins produced by the ent. faecalis strains showed a narrow spectrum of activity, mainly against other enterococcus ... | 2000 | 10747229 |
| [in vitro activities of levofloxacin and other antibiotics against fresh clinical isolates]. | in this study, the in vitro activity of levofloxacin (lvfx) against 1,020 fresh bacterial clinical isolates was compared with the activities of a range of ofloxacin, ciprofloxacin (cpfx), ampicillin (abpc), cefaclor, cefpodoxime, methicillin and benzylpenicillin. the clinical isolates except vibrio cholerae were collected in japan during 1998 from patients with infectious diseases. mics were determined using the agar dilution method according to the recommendations by the japan society of chemot ... | 1999 | 10746192 |
| evaluation of biosynthetic pathways to delta-aminolevulinic acid in propionibacterium shermanii based on biosynthesis of vitamin b12 from d-[1-13c]glucose. | analysis of the (13)c nuclear magnetic resonance (nmr) spectrum of (13)c-labeled vitamin b(12) biosynthesized from d-[1-(13)c]glucose by propionibacterium shermanii provided evidence suggesting that delta-aminolevulinic acid (ala) incorporated in the (13)c-labeled vitamin b(12) may have been synthesized via both the shemin pathway and the c5 pathway under anaerobic conditions in the ratio of 1 < [(ratio of ala biosynthesis from the shemin pathway)/(that from the c5 pathway)] < 1.8. the d-ribose ... | 2000 | 10736165 |
| enterocin 012, a bacteriocin produced by enterococcus gallinarum isolated from the intestinal tract of ostrich. | enterococcus gallinarum strain 012, isolated from the duodenum of ostrich, produced enterocin 012 which is active against ent. faecalis, lactobacillus acidophilus, lact. sake, listeria innocua, propionibacterium acidipropionici, propionibacterium sp., clostridium perfringens, pseudomonas aeruginosa and salmonella typhimurium. one of the four pathogenic strains of escherichia coli isolated from the intestinal tract of ostrich was inhibited by enterocin 012. no antimicrobial activity was recorded ... | 2000 | 10736005 |
| [prognosis of postoperative endophthalmitis]. | the outcome of 20 patients is summarized in a retrospective study to identify clinical findings that influence the long-term prognosis of postoperative endophthalmitis. | 2000 | 10734738 |
| effects of cannabinoid receptor agonist and antagonist ligands on production of inflammatory cytokines and anti-inflammatory interleukin-10 in endotoxemic mice. | previous studies have shown that mice primed with corynebacterium parvum produce higher levels of inflammatory cytokines than unprimed mice upon challenge with lipopolysaccharide (lps). herein, we describe experiments in which two cannabinoid (cb) agonists, win 55212-2 [(r)-(+)-[2, 3-dihydro-5-methyl-3-[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]1, 4-benzoxazin-6-yl](1-naphthyl)methanone) and hu-210 [(-)-11-hydroxy-delta(8) tetrahydrocannabinol-dimethylheptyl], were examined for their effects on lps ... | 2000 | 10734163 |
| the role of probiotic cultures in the control of gastrointestinal health. | the use of probiotics to enhance intestinal health has been proposed for many years. probiotics are traditionally defined as viable microorganisms that have a beneficial effect in the prevention and treatment of specific pathologic conditions when they are ingested. there is a relatively large volume of literature that supports the use of probiotics to prevent or treat intestinal disorders. however, the scientific basis of probiotic use has been firmly established only recently, and sound clinic ... | 2000 | 10721914 |
| safety, efficacy, and functionality of high-field strength interventional magnetic resonance imaging for neurosurgery. | interventional magnetic resonance imaging (mri) allows neurosurgeons to interactively perform surgery using mri guidance. high-field strength (1.5-t) imaging permits exceptional observation of intracranial and spinal pathological features. the development of this technology and its application to a variety of neurosurgical procedures are described. | 2000 | 10719860 |
| inability of dairy propionibacteria to grow in milk from low inocula. | growth of propionibacteria in complex media was independent of the initial number of cells; in contrast, growth of propionibacteria in milk and whey did not occur if the initial level of cells was < 10(6) cfu/ml. addition of vitamins, minerals or complex nitrogen sources to the milk or whey, or incubation under anaerobic conditions had no effect on the lack of growth. addition of freeze-dried whey, prepared from skim milk reconstituted from powder, to a complex medium prevented growth from low i ... | 2000 | 10717844 |
| altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage. | although obesity-related fatty livers are vulnerable to damage from endotoxin, the mechanisms involved remain obscure. the purpose of this study was to determine if immunologic priming might be involved by determining if fatty livers resemble normal livers that have been sensitized to endotoxin damage by propionibacterium acnes infection. the latter induces interleukin (il)-12 and -18, causing a selective reduction of cd4+nk t cells, diminished il-4 production, deficient production of t-helper t ... | 2000 | 10706553 |
| postoperative endophthalmitis caused by sequestered acinetobacter calcoaceticus. | to describe postoperative endophthalmitis caused by sequestered acinetobacter calcoaceticus. | 2000 | 10704562 |
| high resolution solution structure of the 1.3s subunit of transcarboxylase from propionibacterium shermanii. | transcarboxylase (tc) from propionibacterium shermanii, a biotin-dependent enzyme, catalyzes the transfer of a carboxyl group from methylmalonyl-coa to pyruvate to form propionyl-coa and oxalacetate. within the multi-subunit enzyme complex, the 1.3s subunit functions as the carboxyl group carrier and also binds the other two subunits to assist in the overall assembly of the enzyme. the 1.3s subunit is a 123 amino acid polypeptide (12.6 kda) to which biotin is covalently attached at lys 89. the t ... | 2000 | 10704200 |
| correlation between bacterial population and axillary and plantar bromidrosis: study of 30 patients. | although studies on the chemistry of odors are expanding to identify the chemical structures of odorous substances, there are no universal standards as yet to measure odor and intensity of bromidrosis. clinical evaluation can be made on a subjective scoring from 0 to 3 prior to prescription of an antiseptic soap. in order to appreciate the correlation between the intensity of bromidrosis (bi) and bacterial activity, a study was carried out with both clinical and bacterial assessment in thirty pa ... | 2000 | 10694297 |
| leucocyte entry and endothelial e-selectin expression following intradermal propionibacterium acnes administration. | immune responses in porcine skin to intradermal inoculation of heat-killed propionibacterium acnes (hkpa), the major bacterial agent associated with human inflammatory acne, were studied. pigs were chosen as experimental animals because their skin is similar in structure and composition to that of man and because the use of genetically inbred pigs enables leucocytes to be transferred between animals without eliciting rejection responses. two pigs were sensitized intradermally with 10 mg of hkpa ... | 2000 | 10684686 |
| [propionibacterium acnes--pathogenetic significance in sarcoidosis?]. | 1999 | 10681204 | |
| susceptibility of anaerobic bacteria in auckland: 1991-1996. | to determine the antimicrobial susceptibility of local anaerobic bacteria. | 1999 | 10678225 |
| [detection of bacterial dna from cholesterol gallstones by np-pcr and its clinical significance]. | to search for bacterial dna sequences in cholesterol gallstones with negative bacterial culture. we used nested primers polymerase chain reaction (np-pcr) technique to amplify bacterial gene fragments were amplified in vitro from dna extracted from cholesterol gallstones. comparative 16s ribosomal rna sequence analysis was used for elucidation of bacterial identification. the gallbladder gallstones of 30 patients were analyzed. bacterial dna was found in the stones of 26 patients. there was no d ... | 1997 | 10678008 |
| natural killer activity in mice infected with rabies virus and submitted to p. acnes (propionibacterium acnes) as immunomodulator. | the natural killer (nk) activity and lethality were evaluated in swiss mice experimentally infected with street rabies virus and submitted to immunomodulation by p. acnes (formerly corynebacterium parvum). the infected animals were sacrificed at different times and spleen non-adherent cells were obtained through ficoll-hypaque gradient and depletion of glass-adherent cells. immunosuppression was observed in rabies virus infected mice correlated with lower nk activity in clinically ill animals. h ... | 2000 | 10670698 |
| topical therapy for acne. | acne is a common problem in adolescents and young adults. the disorder is caused by abnormal desquamation of follicular epithelium that results in obstruction of the pilosebaceous canal. this obstruction leads to the formation of comedones, which can become inflamed because of overgrowth of propionibacterium acnes. topical retinoids such as tretinoin or adapalene are effective in many patients with comedonal acne. patients with inflammatory lesions benefit from treatment with benzoyl peroxide, a ... | 2000 | 10670502 |
| evaluation of the oxyrase oxyplate anaerobe incubation system. | the oxyrase oxyplate anaerobe incubation system was evaluated for its ability to support the growth of clinically significant anaerobic bacteria previously identified by the anaerobe reference laboratory at the centers for disease control and prevention. the results were compared with those obtained with conventional anaerobe blood agar plates incubated in an anaerobe chamber. we tested 251 anaerobic bacterial strains. plates were read at 24, 48, and 72 h; growth was scored by a numerical coding ... | 2000 | 10655335 |
| antibacterial and antiandrogen flavonoids from sophora flavescens. | sixteen flavanones, three flavanonols, and four pterocarpans were isolated from the meoh extract of the roots of sophora flavescens. twelve of these were new compounds, including eight prenylflavanones (1-8), one prenylflavanonol (9) and three novel pterocarpane derivatives (10-12). their structures were elucidated using nmr and mass spectral methods. some of these compounds have irregular c10 prenyl moieties at c-8 of the flavanone skeleton. these compounds exhibited significant antibacterial a ... | 1999 | 10654410 |
| metronidazole, its bioactive metabolites and acne. | metronidazole's activity has been established in both acneiform rosacea and acne vulgaris. recent research indicating that the breakdown products of several antibiotics, including metronidazole, may have considerably greater activity than the parent compound, prompted a re-examination of the susceptibility of propionibacterium acnes, the organism involved in the fundamental pathogenesis of acne vulgaris. although the organism was marginally more sensitive to the hydroxy derivative, mic levels we ... | 1999 | 10640262 |
| optimizing breast pocket irrigation: an in vitro study and clinical implications. | subclinical infections have been implicated in the etiology of capsular contracture. intraoperatively, breast pocket irrigation with povidone-iodine or other antibiotic solutions has been popularized; however, detrimental effects on wound healing for these agents have been reported and their efficacy against common organisms found around breast implants has not been studied. the purpose of this study was to compare the in vitro efficacy of serial dilutions of povidone-iodine and two double antib ... | 2000 | 10627003 |
| propionibacterium acnes as the cause of endocarditis in a liver transplant recipient. | 2000 | 10619770 | |
| hepatic granuloma due to propionibacterium acnes in a patient with acute myelogenous leukemia. | 2000 | 10619766 | |
| [the evaluation of the use of antineoplaston as2-1 treatment in subacute sclerosing panencephalitis]. | a follow-up study was carried out of 16 sspe patients two years after completion of 6-month treatment with antineoplaston. the study was based on an inquiry sent to the families of the patients and on control examinations at the clinic. in the period of follow-up 6 patients died, all had the downhill type of disease course and their mean survival was 18 months. out of the remaining 10 patients 4 are in stationary condition and the remaining ones had minimal worsening. a more detailed clinical an ... | 1999 | 10612094 |
| [apropos of recommendations concerning oral treatment of acne. an interview with the president s. belaich. interview by hélne allouch]. | 1999 | 10605477 | |
| [oral treatment of acne. agence française de securité sanitaire des produits de santé]. | 1999 | 10605476 | |
| in-vitro and in-vivo efficacy of zinc acetate against propionibacteria alone and in combination with erythromycin. | some studies have been published about the in vitro activity of zinc acetate (za), erythromycin (e) and their combination (za/e) against propionibacterium spp., especially erythromycin resistant strains. the efficacy of topical za/e combination has been reported as well, but a comparison to za monotherapy is missing. therefore, the mic values of za, e and the za/e combination were determined for 15 erythromycin-resistant and 12 erythromycin-sensitive propionibacterium strains using the agar dilu ... | 1999 | 10603662 |
| treatment strategies for postoperative propionibacterium acnes endophthalmitis. | propionibacterium acnes endophthalmitis after cataract extraction and posterior chamber intraocular lens (iol) implantation is characterized by a chronic indolent course, frequently associated with recurrence after standard endophthalmitis treatment. this study was designed to evaluate the efficacy of various therapeutic methods in the treatment of primary and recurrent episodes of postoperative p. acnes endophthalmitis. | 1999 | 10599678 |
| update on acute and chronic endophthalmitis. | 1999 | 10599651 | |
| characterization of pentocin tv35b, a bacteriocin-like peptide isolated from lactobacillus pentosus with a fungistatic effect on candida albicans. | lactobacillus pentosus tv35b, isolated from the posterior fornix secretions of the vagina of a prenatal patient, produced a bacteriocin-like peptide (pentocin tv35b), which is inhibitory to clostridium sporogenes, cl. tyrobutyricum, lact. curvatus, lact. fermentum, lact. sake, listeria innocua, propionibacterium acidipropionici, propionibacterium sp. and candida albicans. the mechanism of activity of pentocin tv35b is bactericidal, as shown by a decrease in the viable cell numbers of lact. sake ... | 1999 | 10594714 |
| coba, a red fluorescent transcriptional reporter for escherichia coli, yeast, and mammalian cells. | we demonstrate the use of propionibacterium freudenreichii uroporphyrinogen iii methyltransferase (coba) as a reporter of gene expression in escherichia coli, fission yeast, and mammalian cells. overexpression of coba in cells resulted in bright red fluorescence that was visualized with standard fluorescence microscopy and fluorescence-activated cell sorting analysis at the single-cell level. as with green fluorescent protein (gfp), no addition of exogenous substrate was required. when expressed ... | 1999 | 10585713 |
| glioblastoma multiforme at the site of metal splinter injury: a coincidence? case report. | the authors report the case of a man who had suffered a penetrating metal splinter injury to the left frontal lobe at 18 years of age. thirty-seven years later the patient developed a left-sided frontal tumor at the precise site of the meningocerebral scar and posttraumatic defect. histological examination confirmed a glioblastoma multiforme adjacent to the dural scar and metal splinters. in addition, a chronic abscess from which propionibacterium acnes was isolated was found within the glioma t ... | 1999 | 10584854 |
| use of agar in ophthalmic pathology: a technique to improve the handling and diagnosis of temporal artery biopsies, subfoveal membranes, lens capsules, and other ocular tissues. | prospective laboratory methodology study. | 1999 | 10571345 |
| role of the dimethylbenzimidazole tail in the reaction catalyzed by coenzyme b12-dependent methylmalonyl-coa mutase. | the recent structures of cobalamin-dependent methionine synthase and methylmalonyl-coa mutase have revealed a striking conformational change that accompanies cofactor binding to these proteins. alkylcobalamins have octahedral geometry in solution at physiological ph, and the lower axial coordination position is occupied by the nucleotide, dimethylbenzimidazole ribose phosphate, that is attached to one of the pyrrole rings of the corrin macrocycle via an aminopropanol moiety. in contrast, in the ... | 1999 | 10563814 |
| [acne and its treatment possibilities]. | acne is a multifactorial disease affecting the pilosebaceous follicles. it is a treatable condition for which the aims of therapy are to reduce social isolation and to prevent or minimise scarring. propionibacterium acnes is an anaerobic bacterium strongly implicated in the pathogenesis of acne. a gradual increase in the resistance of p. acnes to many antibiotics has been documented in the last decade, and there is thus a growing need to use either appropriate antibiotics or even change the ther ... | 1999 | 10555254 |
| effects of orally administered viable lactobacillus rhamnosus gg and propionibacterium freudenreichii subsp. shermanii js on mouse lymphocyte proliferation. | immunomodulation by probiotics is a subject of growing interest, but the knowledge of dose response and time profile relationships is minimal. in this study we examined the effects of lactobacillus rhamnosus gg (lgg) and propionibacterium freudenreichii subsp. shermanii js (pjs) on the proliferative activity of murine lymphocytes ex vivo. dose dependency was assessed by treating animals perorally with a low or a high dose (i.e., 10(9) or 10(12) viable bacteria/kg of body weight) for 7 days. the ... | 1999 | 10548566 |
| experimental liver injury induced by propionibacterium acnes and lipopolysaccharide in macrophage colony stimulating factor-deficient osteopetrotic (op/op) mice. | to clarify the involvement of growth and differentiation of liver macrophages mediated by macrophage colony-stimulating factor (m-csf) in the liver injury induced by propionibacterium acnes (p. acnes) and lipopolysaccharide (lps), we used m-csf-deficient osteopetrotic (op/op) mice. seven days after injection of p. acnes, granulomas as well as the numbers of thy-1.2-, mac-1-, and ermp-20-positive cells and f4/80-positive areas in the liver were significantly reduced in the op/op mice compared to ... | 1999 | 10548345 |
| [spondylodiscitis due to propionibacterium acnes. case report and review of the literature]. | propionibacterium acnes, a gram positive anaerobic organism, is a component of normal skin flora. it can exceptionally be a source of osteoarticular infection (osteitis, arthritis, spondylodiscitis). we report a case of propionibacterium acnes spondylodiscitis following lumbar puncture. this observation should alert the clinician to the fact that propionibacterium acnes may rarely cause spondylodiscitis and lumbar pain, and should be considered a causative agent of bone infections after local pr ... | 1999 | 10546305 |
| in vitro utilization of amylopectin and high-amylose maize (amylomaize) starch granules by human colonic bacteria. | it has been well established that a certain amount of ingested starch can escape digestion in the human small intestine and consequently enters the large intestine, where it may serve as a carbon source for bacterial fermentation. thirty-eight types of human colonic bacteria were screened for their capacity to utilize soluble starch, gelatinized amylopectin maize starch, and high-amylose maize starch granules by measuring the clear zones on starch agar plates. the six cultures which produced cle ... | 1999 | 10543795 |
| digital fluorescence photography can assess the suppressive effect of benzoyl peroxide on propionibacterium acnes. | porphyrins produced by propionibacterium acnes exhibit an orange-red fluorescence under uva light. the amount of fluorescence can be estimated by digital fluorescence photography. | 1999 | 10534632 |
| echocardiographic and survival studies in mice undergoing endotoxic shock: effects of genetic ablation of inducible nitric oxide synthase and pharmacologic antagonism of platelet-activating factor. | evidence implicating inducible nitric oxide synthase (inos) in the alterations of cardiac function characteristic of septic shock has come mostly from studies on anesthetized animals, isolated hearts, cultured myocytes, or hosts treated with pharmacologic inhibitors that lack complete specificity for inos. platelet-activating factor (paf) can participate in the induction of inos and has also been implicated in cardiac dysfunction in sepsis. the present studies assessed cardiac function in a mode ... | 1999 | 10534424 |
| dexamethasone differentially regulates cytokine transcription and translation in macrophages responding to bacteria or okadaic acid. | many microorganisms and microbial products induce expression of pro-inflammatory cytokines such as interleukin-1 (il-1alpha/beta) and tumour necrosis factor-alpha (tnf-alpha) in macrophages, primarily by transcriptional activation. we show here, by using mouse macrophages in primary culture, that pre-treatment with dexamethasone inhibits bacteria-induced il-1beta expression as mrna and cellular pro-il-1beta in parallel, consistent with an effect primarily on transcriptional activation. in contra ... | 1999 | 10530874 |
| beta-hemolytic streptococci and other beta-hemolytic organisms in apical periodontitis and severe marginal periodontitis. | thirteen teeth with necrotic pulps and apical periodontitis and nine severe periodontal pockets were cultured for presence of beta-hemolytic streptococci and other beta-hemolytic organisms. samples were dispersed and plated on two non-selective and one selective growth media and incubated anaerobically and in 10% co2 in air. a total of 59 beta-hemolytic colonies were purified and identified. eight beta-hemolytic streptococcal isolates were obtained from three of the severe marginal periodontitis ... | 1999 | 10530151 |
| pharmacokinetics and pharmacodynamics of vecuronium in rats with systemic inflammatory response syndrome: treatment with ng-monomethyl-l-arginine. | insufficient detoxification caused by nitric oxide-related inhibition of cytochrome p450 may be important for metabolism of numerous drugs, including vecuronium. the present study investigated the pharmacodynamics and pharmacokinetics of vecuronium in rats with inflammatory liver dysfunction. | 1999 | 10519503 |
| caspase-1-independent, fas/fas ligand-mediated il-18 secretion from macrophages causes acute liver injury in mice. | il-18, produced as a biologically inactive precursor, is processed by caspase-1 in lps-activated macrophages. here, we investigated caspase-1-independent processing of il-18 in fas ligand (fasl)-stimulated macrophages and its involvement in liver injury. administration of propionibacterium acnes (p. acnes) upregulated functional fas expression on macrophages in an ifngamma-dependent manner, and these macrophages became competent to secrete mature il-18 upon stimulation with fasl. this was also t ... | 1999 | 10514014 |
| gallium nitrate suppresses the production of nitric oxide and liver damage in a murine model of lps-induced septic shock. | the efficacy of gallium (ga) nitrate was examined in a murine model of sepsis. male balb/c mice (6-8 weeks) were randomized into 3 groups: 1) vehicle-treated controls 2) mice with sepsis induced by treatment with 0.3 mg i.v. of propionibacterium acnes followed one week later by 0.01 microg lipopolysaccharide (lps) and 10 mg of d-galactosamine (galn) 3) mice with sepsis injected with 45 mg/kg s.c. of gallium nitrate (calculated as elemental ga) 24 hours prior to lps/galn. two hours after lps/galn ... | 1999 | 10503955 |
| expression and biotinylation of a mutant of the transcarboxylase carrier protein from propioni shermanii. | a deletion mutant (residues 10 to 48 cut) of the biotinyl subunit (tcc) from the enzyme transcarboxylase (ec 2.1.3.1) of propioni shermanii was overexpressed in escherichia coli. complete biotinylation of the protein was achieved by addition of exogenous biotin and coexpression of the biotin holoenzyme synthetase (ec 6.3. 4.15.) from e. coli. the transcription of both genes was put under control of different operators/promoters, thus achieving independent control of expression levels and optimiz ... | 1999 | 10497077 |
| propionibacterium acnes induces acute tnfalpha-mediated apoptosis of hepatocytes followed by inflammatory t-cell-mediated granulomatous hepatitis in mice. | the cd3+/tcralphabeta+ t-cell-mediated hepatic inflammation induced by propionibacterium acnes could be divided into an acute and a chronic phase. the acute phase occurred within 72 h after injection and displayed hepatic apoptosis. anti-tnfalpha antibody inhibited both the p. acnes-induced hepatic apoptosis and lymphocyte infiltration seen in this phase, indicating the involvement of this cytokine. thereafter, a chronic phase was manifested from days 7 to 14 after injection. it was characterize ... | 1999 | 10494042 |
| jte-607, a novel inflammatory cytokine synthesis inhibitor without immunosuppression, protects from endotoxin shock in mice. | we investigated the effect of a novel n-benzoyl-l-phenylalanine derivative compound (jte-607) on production of various cytokines and other immune responses in vitro and on endotoxin shock in vivo. | 1999 | 10493164 |
| [development of a vaccine for treatment of urinary tract infections]. | receiving uroinfections are predominantly treated with antibiotics and chemotherapeutics. an effective alternative treatment can be immunotherapy with inactivated bacteria. the authors have focused on the development of polybacterial vaccine with both specific and nonspecific immunostimulatory activity. the vaccine contains killed bacteria which most frequently occur as an etiological agent in urinary tract infections. determining for the selection of particular strains for the vaccine preparati ... | 1999 | 10493005 |
| acne vulgaris: state of the science. | 1999 | 10490115 | |
| detection of prosthetic hip infection at revision arthroplasty by immunofluorescence microscopy and pcr amplification of the bacterial 16s rrna gene. | in this study the detection rates of bacterial infection of hip prostheses by culture and nonculture methods were compared for 120 patients with total hip revision surgery. by use of strict anaerobic bacteriological practice during the processing of samples and without enrichment, the incidence of infection by culture of material dislodged from retrieved prostheses after ultrasonication (sonicate) was 22%. bacteria were observed by immunofluorescence microscopy in 63% of sonicate samples with a ... | 1999 | 10488193 |
| microbiology of infected pustular psoriasis lesions. | bacterial infections can occur in lesions of pustular psoriasis (pp). the objective of this study was to establish the aerobic and anaerobic microbiology of secondarily infected pp. | 1999 | 10487445 |
| treatment strategies and visual acuity outcomes in chronic postoperative propionibacterium acnes endophthalmitis. | to report the treatment strategies and visual acuity outcomes of chronic postoperative endophthalmitis caused by propionibacterium acnes. | 1999 | 10485532 |
| [bacterial keratitis. microbiological analysis as a principle for therapeutic recommendations]. | the study presented differentiates between the aetiological agents of bacterial keratitis in patients with and without a history of contact lens wear. based on these results, recommendations are given for optimal antibiotic primary therapy. | 1999 | 10479898 |
| antibacterial activity of retinaldehyde against propionibacterium acnes. | retinaldehyde has been shown to exert antibacterial activity in vitro. | 1999 | 10473957 |
| genus- and species-specific pcr-based detection of dairy propionibacteria in environmental samples by using primers targeted to the genes encoding 16s rrna. | pcr assays with primers targeted to the genes encoding 16s rrna were developed for detection of dairy propionibacteria. propionibacterium thoenii specific oligonucleotide pt3 was selected after partial resequencing. tests allowed the detection of less than 10 cells per reaction from milk and cheese and 10(2) cells per reaction from forage and soil. | 1999 | 10473444 |
| recalcitrant acne vulgaris secondary to a dental abscess. | this case report describes a middle-aged man with acne that was recalcitrant to numerous medications, including three courses of isotretinoin. his condition cleared after an infected tooth was removed and recurred when another tooth became carious. acne vulgaris is associated with several immunologic responses including the production of antibodies against propionibacterium acnes, the gram-positive bacteria found in acne lesions. we believe that the presence of our patient's dental infections pr ... | 1999 | 10467506 |
| glycopeptide tolerance in bacteria causing endocarditis. | glycopeptides have been recommended as therapy for endocarditis. mics and mbcs of vancomycin and teicoplanin were compared for 100 isolates from patients with proven bacterial endocarditis. mics were generally lower for teicoplanin and tolerance to both agents was common. almost all isolates of enterococci were tolerant to both glycopeptides. among the streptococci, 78% were tolerant to teicoplanin and 57% to vancomycin. similar findings were demonstrated for staphylococci. although isolates app ... | 1999 | 10459820 |
| positive vitreous cultures in eyes with retained lens fragments. | 1999 | 10458307 | |
| protection by a cyclic amp-specific phosphodiesterase inhibitor, rolipram, and dibutyryl cyclic amp against propionibacterium acnes and lipopolysaccharide-induced mouse hepatitis. | to study the effect of cellular camp-increasing agents on propionibacterium acnes (p. acnes) and lipopolysaccharide (lps)-induced mouse hepatitis. | 1999 | 10450787 |
| [acne vulgaris: local and systemic treatment]. | acne vulgaris is a skin disease affecting mainly young people. to its pathogenetical factors belong: excessive serum production, cornification of hair follicles and presence of different bacteria (propionibacterium acnes, staphylococcus epidermidis, pityrosporum ovale) on the skin and within hair follicles leading to skin inflammation. therapeutical approach to the patient depends on the clinical presentation of the disease. and so, in its local treatment are benzyl peroxide, azelaic acid, topic ... | 1999 | 10437405 |
| [an analysis of the cause of misdiagnosis with ocular opportunistic infection]. | to evaluate the causes of misdiagnosis with ocular opportunistic infection. | 1997 | 10437001 |
| reversal of c-anca positive mesangiocapillary glomerulonephritis after removal of an infected cysto-atrial shunt. | 1999 | 10435894 | |
| acne: a review of immunologic and microbiologic factors. | acne vulgaris is a self-limiting skin disorder seen primarily in adolescents, whose aetiology appears to be multifactorial. the four main aetiological factors are hypercornification of the pilosebaceous duct, increased sebum production, colonization with propionibacterium acnes, and subsequently the production of inflammation. considerable investigation has addressed the immunologic reaction to extracellular products produced by the acne-causing organism, p acnes. the immunologic response involv ... | 1999 | 10435165 |
| structure and dynamics of the b12-binding subunit of glutamate mutase from clostridium cochlearium. | glutamate mutase (glm) is an adenosylcobamide-dependent enzyme that catalyzes the reversible rearrangement of (2s)-glutamate to (2s, 3s)-3-methylaspartate. the active enzyme from clostridium cochlearium consists of two subunits (of 53.6 and 14.8 kda) as an alpha2beta2 tetramer, whose assembly is mediated by coenzyme b12. the smaller of the protein components, glms, has been suggested to be the b12-binding subunit. here we report the solution structure of glms, determined from a heteronuclear nmr ... | 1999 | 10429202 |
| atp synthesis by f-type atp synthase is obligatorily dependent on the transmembrane voltage. | atp synthase is the universal enzyme that manufactures cellular atp using the energy stored in a transmembrane ion gradient. this energy gradient has two components: the concentration difference (deltaph or deltapna(+)) and the electrical potential difference deltapsi, which are thermodynamically equivalent. however, they are not kinetically equivalent, as the mitochondrial and bacterial atp synthases require a transmembrane potential, deltapsi, but the chloroplast enzyme has appeared to operate ... | 1999 | 10428951 |
| activity of telithromycin (hmr 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology. | time-kill studies examined the activities of telithromycin (hmr 3647), erythromycin a, azithromycin, clarithromycin, roxithromycin, clindamycin, pristinamycin, amoxicillin-clavulanate, and metronidazole against 11 gram-positive and gram-negative anaerobic bacteria. time-kill studies were carried out with the addition of oxyrase in order to prevent the introduction of co(2). macrolide-azalide-ketolide mics were 0.004 to 32.0 microg/ml. of the latter group, telithromycin had the lowest mics, espec ... | 1999 | 10428930 |
| how stable is stable? function versus community composition. | the microbial community dynamics of a functionally stable, well-mixed, methanogenic reactor fed with glucose were analyzed over a 605-day period. the reactor maintained constant ph and chemical oxygen demand removal during this period. thirty-six rrn clones from each of seven sampling events were analyzed by amplified ribosomal dna restriction analysis (ardra) for the bacteria and archaea domains and by sequence analysis of dominant members of the community. operational taxonomic units (otus), d ... | 1999 | 10427068 |
| in vitro viability of external eye microbial flora in hydroxy-propyl-methylcellulose. | the aim of this study was to verify the in vitro influence of various dilutions of a viscoelastic substance containing 2% hydroxy-propyl-methylcellulose (hpmc) on the viability of some microbial strains representative of the normal flora of the external eye. pure reference strain cultures of candida albicans, pseudomonas aeruginosa, propionibacterium acnes, staphylococcus aureus, staphylococcus epidermidis and a fresh clinical isolate of proteus mirabilis were selected for this study. serial two ... | 1999 | 10420112 |
| effect of bacillus of calmette-guérin, avridine and propionibacterium acnes as immunomodulators on rabies in mice. | the cellular and humoral immune responses of mice inoculated with rabies virus and treated with the bacillus of calmette-guérin, avridine and propionibacterium acnes were evaluated in this paper. there was a higher percentage of surviving mice in groups submitted to p. acnes treatment. lower levels of interferon-gamma (ifn-gamma) were found in infected mice. the intra-pad inoculation test (ipi) was not effective to detect cellular immune response, contrary to the results found in mif reaction. t ... | 1999 | 10413958 |
| [thoracic actinomycosis--a case report]. | background: actinomycosis is caused by a variety of gram-positive anaerobic or microaerophilic rods belonging to the genus actinomyces or propionibacterium. the production of suppurative abscesses or granulomas that eventually develop draining sinuses are hallmarks of the disease. we describe the case of a 55 year old smoker who presented himself 4 months ago with right thoracic pain and an unproductive cough. he developed a warm, red mass in the lower part of the right thorax. we performed an u ... | 1999 | 10409866 |
| quantitative pcr of mycobacterial and propionibacterial dna in lymph nodes of japanese patients with sarcoidosis. | the causes of sarcoidosis are not known. the dna of mycobacterium tuberculosis has been detected in some sarcoid lesions. in japan, propionibacterium acnes has been isolated from such lesions, but whether this indigenous bacterium is related to the disease is unclear. we used pcr to estimate the number of genomes of these bacteria in sarcoid lesions, to identify any link between sarcoidosis and these two bacterial species. | 1999 | 10408488 |
| [bacterial keratitis in patients with and without contact lens anamnesis]. | the study shows differences between contact lens wearers and patients without history of contact lenses regarding the spectrum of etiological agents in bacterial keratitis. based on microbiological analysis, there are given recommendations for an optimal initial antibiotic treatment in both groups. | 1999 | 10407802 |
| use of a low nutrient culture medium for the identification of bacteria causing severe ocular infection. | a low nutrient culture medium was used to identify the pathogens in four cases of persisting ocular infection. bacto r2a agar was used in addition to conventional liquid- and solid-phase media to culture pathogenic bacteria from one case of recurrent keratitis, one case of suture-related keratitis with endophthalmitis and two eyes (two patients) with post-operative endophthalmitis. in each case, a pathogen was identified solely with r2a agar after culture for 6 days. species isolated were pseudo ... | 1999 | 10403423 |
| [endocarditis of the native aortic valve due to propionibacterium acnes]. | 1999 | 10396160 | |
| antibacterial efficacy of benzoyl peroxide in phospholipid liposomes. a vehicle-controlled, comparative study in patients with papulopustular acne. | literature reports indicate that phospholipid liposomes facilitate the accumulation of active agents in the infundibulum. | 1999 | 10393452 |
| effect of the bacillus of calmette-guérin, propionibacter acnes and avridine as immunomodulators in antirabies vaccination of mice using the fuenzalida-palacios mouse brain vaccine. | using the laboratory mice, fuenzalida-palacios mouse brain human rabies vaccine was administered in groups of animals previously inoculated with rabies virus and then submitted to treatments with the immunomodulators onco-bcg, avridine and propionibacterium acnes. humoral and cellular immune responses were evaluated through the macrophage inhibition factor (mif), intra-pad inoculation (ipi) and serum neutralization (sn) tests and by the detection of gamma-interferon (ifn-gamma). the ipi test was ... | 1999 | 10392627 |