Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| effect of aspoxicillin on anaerobic bacteria. | aspoxicillin (aspc), a semisynthetic penicillin has a broad spectrum of antibacterial activities against gram-positive and gram-negative anaerobic bacteria. its in vitro antibacterial activity was less than those of cefoxitin against peptostreptococcus and veillonella, but was significantly high against bacteroides fragilis, one of the most clinically important anaerobe. the therapeutic and/or protective effect of aspc in experimental subcutaneous abscess or experimental intraabdominal mixed inf ... | 1985 | 3850132 |
| enzymatic reduction of sennidin and sennoside in peptostreptococcus intermedius. | peptostreptococcus intermedius, one of the dominant bacteria of human intestine, reduced sennidin and sennoside to rheinanthrone and 8-glucosyl-rheinanthrone, respectively, and these reduction rates were stimulated by the addition of nicotinamide adenine dinucleotide (reduced form) (nadh), flavin adenine dinucleotide (fad) and glucose. the reduction was accelerated by removing oxygen from the incubation tubes, which indicates the inhibition of the reduction by o2. thus, for the maximal activity, ... | 1985 | 3841560 |
| [2 cases of pneumonia with empyema caused by anaerobic micro-organisms in childhood]. | 1986 | 3826924 | |
| bacteraemia and seeding of capsulate bacteroides spp. and anaerobic cocci. | the effect of capsulation on the ability of bacteroides fragilis, b. asaccharolyticus and anaerobic gram-positive cocci to induce bacteraemia and seeding to various organs was investigated. the test species were injected into mice subcutaneously alone, or mixed with other aerobic or facultative organisms. capsulate anaerobes were isolated more frequently from the blood, spleen, liver, and kidneys of infected animals than were non-capsulate organisms. after injection of single anaerobic strains, ... | 1987 | 3820272 |
| microbiology of retropharyngeal abscesses in children. | aspiration of retropharyngeal abscesses was performed in 14 children. cultures were taken from aspirates for aerobic and anaerobic bacteria, and all yielded bacterial growth. anaerobes were isolated in all patients; they were the only organisms isolated in two patients (14%) and were mixed with aerobes in 12 patients (86%). there were 78 anaerobic isolates (5.6 per specimen). the predominant anaerobes were bacteroides species, peptostreptococcus species, and fusobacterium species. there were 26 ... | 1987 | 3812388 |
| analysis of edta-soluble cell surface components of gram-positive anaerobic cocci. | the protein content of edta extracts from 76 strains of gram-positive anaerobic cocci was examined using sds-page. strains of peptostreptococcus anaerobius produced almost identical profiles; greater heterogeneity was observed within the species peptococcus magnus, peptococcus prevotii and peptococcus asaccharolyticus, but several strains within each biotype produced similar patterns. serological investigation of these extracts by elisa revealed numerous cross-reactions among the different bioty ... | 1986 | 3806050 |
| proline requirement for glucose utilization by peptostreptococcus anaerobius atcc 27337. | resting cells of peptostreptococcus anaerobius maintained under anaerobic conditions were unable to metabolize either glucose or alanine. the addition of proline to the appropriate suspension, however, resulted in the immediate utilization of both compounds. fermentation of alanine by the cells required that stoichiometric concentrations of proline be present in the medium; and during the oxidation of alanine, proline was simultaneously reduced to the ring cleavage product delta-aminovaleric aci ... | 1987 | 3804441 |
| mutagenic activation of biliary metabolites of benzo(a)pyrene by beta-glucuronidase-positive bacteria in human faeces. | human faeces hydrolysed synthetic beta-d-glucuronides of both p-nitrophenol and phenolphthalein. the origin of this activity in faeces was localised in the bacterial pellet fraction after centrifugation. ninety-seven bacterial strains with beta-glucuronidase activity isolated from fresh human faeces were identified as species of bacteroides, peptostreptococcus, fusobacterium, propionibacterium, clostridium, eubacterium and bifidobacterium. they were classified into two groups according to their ... | 1986 | 3795254 |
| short-term failure of iud removal to alter bacterial flora in a patient with chronic anaerobic endometritis. | a patient with cytological and clinical evidence of iud-associated anaerobic endometritis was studied with quantitative and qualitative bacteriological techniques. with the exception of elimination of actinomyces israelii from the deep endocervical/endometrial culture, iud removal induced minimal qualitative changes in the bacterial flora of the endocervical/endometrial sample during the 35 days the patient was monitored. the interposition of menstruation did not significantly alter either the q ... | 1986 | 3789249 |
| isolation and characterization of a mucin-degrading strain of peptostreptococcus from rat intestinal tract. | a mucin-degrading microorganism was isolated from the intestinal tract by serial sectioning from the serosal side of the caecum wall from a conventional rat. the ability of degrading the intestinal water-soluble mucin was present both in vivo after monocontamination of germ-free rats and in vitro, when adding the microbe to mucin medium. the morphology, gram-positive cocci single or in short chains and the very weak biochemical activities allow us to place this strain in the species peptostrepto ... | 1986 | 3788570 |
| [studies of the sensitivity of absolute anaerobes to antibiotics and metronidazole (determination of minimal inhibitory concentrations-mic)]. | 1986 | 3776192 | |
| peptostreptococcal vertebral osteomyelitis. | the clinical course of a patient with vertebral osteomyelitis caused by peptostreptococcus micros is described. the organism was isolated on two occasions from lumbar vertebral biopsies and was visualized in histologic sections of one of the biopsies. the patient had no apparent infections at other body sites. the infection was eradicated after 6 weeks of intravenous clindamycin therapy. | 1986 | 3771752 |
| diabetic foot infections. bacteriologic analysis. | diabetic patients with foot infections were prospectively evaluated over a two-year period. cultures from reliable specimens avoiding contamination with foot ulcers were obtained in 54 infectious episodes. staphylococcus species, enterococcus species, corynebacterium species, and various species of enterobacteriaceae were commonly isolated. common anaerobic isolates included peptostreptococcus magnus, peptostreptococcus prevotii, and bacteroides species. results of cultures from 94 unreliable sp ... | 1986 | 3767539 |
| [effect of metronidazole on the course of experimental anaerobic streptococcal pneumonia]. | the effect of metronidazole in experimental anaerobic pneumonia in guinea pigs infected with peptostreptococci has been studied. in the untreated animals the prolonged pathological process in the lungs is mainly associated with the suppression of the functional state of the thymus-dependent link of the immune system. metronidazole suppresses anaerobic flora, stimulates local immune reaction and arrests the development of inflammatory changes in the lungs. the drug eliminates the unbalance in som ... | 1986 | 3765970 |
| [meningitis and brain abscess caused by anaerobic bacteria in an infant]. | 1986 | 3765691 | |
| [the role of intrauterine contraceptive devices in the development of inflammatory processes in the small pelvis]. | the incidence of pelvic inflammatory disease (pid) attributable to iud use has been increasing, especially after the removal of the dalkon shield from the market, but this relationship has not been settled conclusively. in recent decades pid included a variety of infections, but lately the definition of pid has meant acute ascending infections of the female genital tract. its most common risk factors include promiscuity of iud use, although this can be reduced to one fourth by regular checkups ... | 1986 | 3763205 |
| [changes in pathogenic microbes in infectious diseases--infections in otorhinolaryngologic diseases]. | 1986 | 3761585 | |
| [a case of peptostreptococcal meningitis associated with subarachnoid hemorrhage and subdural hematoma]. | a very rare case of peptostreptococcal meningitis associated with subarachnoid hemorrhage and subdural hematoma was reported. a 25-year-old man was admitted to st. mary's hospital on november 6, 1984 with a few day's history of headache and low grade fever. on admission, he had high grade fever (39.2 degrees c) and tachycardia (110/min). there were no neurological deficits other than neck stiffness and kernig's sign. the cerebrospinal fluid (csf) which was obtained through lumbar puncture showed ... | 1986 | 3741708 |
| microbiologic analyses of nasal polyp tissue. | nasal polyps from 40 patients were cultured within 2 1/2 hours after surgical removal to determine whether microorganisms were present. the first 20 polyps were cultured for aerobic and anaerobic bacteria, viruses, fungi, mycoplasmas, and mycobacteria. of these 20 polyps, eight were sterile by all tests, one grew cryptococcus albidus, one grew sporobolomyces, one had large numbers of peptostreptococcus micros and propionibacterium acnes, greater than 10(6) colony-forming units per gram (cfu/gm), ... | 1986 | 3722630 |
| immunochemical characterization of the cell surface carbohydrate antigens of peptostreptococcus anaerobius. | two carbohydrate antigens were isolated from the cell surface of peptostreptococcus anaerobius. one, extracted from purified cell walls with naoh, contained glucose and phosphorus, with traces of galactosamine and glucosamine. serological activity was detected by a 'dot blot' procedure. the second antigen, extracted from cell membranes with phenol and purified by chromatography on sepharose 6b and an immunoadsorbent column, contained glucose, glycerol phosphate, phosphorus and fatty acids. antig ... | 1986 | 3711862 |
| [study of concentrations of clindamycin phosphate in bone marrow blood and tissue]. | clindamycin phosphate (cldm) was administered to 33 surgical cases in orthopedics to treat or prevent infection (600 mg in 15 cases and 1,200 mg in 18 cases by intravenous drip infusion over 60 minutes) and the concentrations of cldm in the bone marrow blood and tissue of the operative field as well as in venous blood were determined with the cup plate method of bioassay by collecting specimens immediately after completion of infusion or 30 or 60 minutes later. the concentration of cldm in bone ... | 1986 | 3702055 |
| comparative activity of sch 34343 against anaerobic bacteria. | the in vitro activity of sch 34343 was compared with that of imipenem, clindamycin, cefoxitin, and metronidazole against 78 strains of anaerobic bacteria in the presence and absence of blood. wilkins-chalgren agar was used. sch 34343 and imipenem were the most active agents, inhibiting all strains at less than or equal to 8 micrograms/ml. the addition of blood had little effect on the activity of any of the agents. seven strains were unable to grow on wilkins-chalgren agar. even with the additio ... | 1986 | 3698546 |
| in vitro activity of ampicillin plus sulbactam against anaerobes compared to ampicillin and cefoxitin. | the antimicrobial susceptibility of 195 recent clinical isolates of anaerobic bacteria was studied to ampicillin alone, ampicillin + 1 mg/l sulbactam, ampicillin + 5 mg/l sulbactam, and cefoxitin by means of agar dilution tests. the ampicillin-sulbactam combinations were the most effective drugs against species of the bacteroides fragilis group, the mic90 of ampicillin + 5 mg/l sulbactam for b. fragilis being less than 1 mg/l, compared to 256 mg/l of ampicillin, 4 mg/l of ampicillin + 1 mg/l sul ... | 1987 | 3692611 |
| the in-vitro activity of doxycycline and minocycline against anaerobic bacteria. | the likelihood of bacterial resistance now prevents the use of oxytetracycline in the empirical therapy of anaerobic infections. this study investigates the in-vitro activity of two semi-synthetic derivatives, doxycycline and minocycline, against a range of anaerobic bacteria. mics for each antibiotic were determined by an agar incorporation technique. doxycycline and minocycline were four to eight times more active against the majority of strains than oxytetracycline. with the exception of bact ... | 1987 | 3680075 |
| enrichment of subgingival microflora on human serum leading to accumulation of bacteroides species, peptostreptococci and fusobacteria. | this study was undertaken to identify ecological factors that favour opportunistic pathogenic species in the subgingival microflora. in a first approach, human serum as a substitute for gingival exudate, was used for batch-wise enrichment of subgingival plaque. the microflora resulting after 5-6 enrichment steps consisted of black-pigmented and non-black-pigmented bacteroides species, peptostreptococcus micros and fusobacterium nucleatum as the main organisms. it is noted that the same group of ... | 1987 | 3674857 |
| interactions of ciprofloxacin with clindamycin, metronidazole, cefoxitin, cefotaxime, and mezlocillin against gram-positive and gram-negative anaerobic bacteria. | a total of 598 clinical isolates of anaerobic bacteria were tested against ciprofloxacin by the agar dilution technique with 10(5) cfu on wilkins-chalgren medium. selected strains representative of the six major genera of anaerobes relatively resistant to the quinolones were tested for interactions with ciprofloxacin in combination with clindamycin, metronidazole, cefoxitin, cefotaxime, or mezlocillin by using a checkerboard agar dilution technique. cefotaxime-ciprofloxacin and clindamycin-cipro ... | 1987 | 3674848 |
| identification of anaerobic bacteria using high-performance liquid chromatography. | 20 species of the genera clostridium, bacteroides, fusobacterium and the type strains of peptostreptococcus anaerobius, peptococcus asaccharolyticus, veillonella parvula and propionibacterium acnes were examined for the production of volatile (vfa) and nonvolatile (nvfa) short-chain fatty acids using high-performance liquid chromatography (hplc) with a column for organic acids (aminex hpx-87h). 10 min are needed for sample preparation and the vfa and nvfa were detected simultaneously in a single ... | 1987 | 3673341 |
| [clinical studies on cefuzonam in obstetrics and gynecological infections]. | to evaluate the usefulness and the safety of cefuzonam (czon, l-105) against obstetric and gynecological infections, we conducted clinical trials and obtained the results summarized as follows. 1. thirteen patients with obstetric and gynecological infections (intrauterine infection 2 cases, adnexitis 7, 1 case each of abscess of adnexa uteri, abscess of the vaginal wall, pyelonephritis, and mammitis) were treated with czon. the czon was administered by intravenous injection or intravenous drip i ... | 1987 | 3669283 |
| [anaerobic bacteria in various infections and their antibiotic susceptibility patterns]. | in this study we have examined antibiotic susceptibility of anaerobic bacteria isolated from various samples of 75 patients. anaerobic bacteria from 22 (29.3%) patients, and only aerobic bacteria from 29 (38.7%) patients have been isolated; there has been no growth in cultures from 24 (32%) patients. of 75 isolates from 51 patients 38 (50.6%) are anaerobic and 37 (49.4%) are aerobic bacteria. following anaerobic bacteria have been isolated: peptostreptococcus (13), peptococcus (5), microaerophil ... | 1986 | 3657617 |
| controlled evaluation of modified radiometric blood culture medium supplemented with gelatin for detection of bacteremia and fungemia. | although the addition of 1.2% gelatin to broth blood culture media containing sodium polyanetholesulfonate has been shown to enhance detection of certain bacteria, including neisseria meningitidis, n. gonorrhoeae, peptostreptococcus anaerobius, and gardnerella vaginalis, the effect of such supplementation on the detection of other microorganisms causing bacteremia and fungemia is not known. therefore, we studied bactec 6b medium with and without gelatin in 6,833 paired comparisons to examine the ... | 1987 | 3624437 |
| increased faecal glycosidases in patients with crohn's disease. | the strictly anaerobic faecal flora of patients with crohn's disease (cd) contains higher numbers of coccoid rods (eubacterium, peptostreptococcus and coprococcus species) and gram-negative rods (bacteroides vulgatus) than the flora of healthy subjects. the abnormal flora of patients with cd might affect levels of glycolytic enzymes and metabolic products and thus play some role in the pathogenesis of cd. therefore, the activity of 23 glycosidases that can degrade mucus glycoproteins or plant po ... | 1987 | 3609504 |
| gastric acidity: an important factor regulating the composition of the bacterial flora in the small intestine. | the role of gastric acidity in regulating the bacterium composition in the small intestine was studied. gastric acidity was determined with the kay test. intestinal juice obtained by a probe was examined for the presence and number of microorganisms. parallel with the increase in gastric acidity, the number of bacteria in the jejunal juice generally decreased. their composition also varied: in anacid patients e. coli predominated whereas in those with free hydrochloric acid, streptococcus alpha ... | 1986 | 3601581 |
| rapid identification of obligately anaerobic gram-positive cocci using high-performance liquid chromatography. | high-performance liquid chromatography was evaluated as a rapid means of identifying obligately anaerobic gram-positive cocci of medical interest. isolates were inoculated into a defined chemical medium consisting primarily of amino acids and were incubated aerobically for 1 h at 35 degrees c. after removal of organisms, the supernatant fluids were derivatized for 1 min at room temperature by the addition of o-phthalaldehyde. the total time required to run a chromatogram was approximately 50 min ... | 1987 | 3597760 |
| heparinase production by anaerobic bacteria. | the production of heparinase by a wide range of anaerobic bacteria isolated from clinical specimens was investigated. none of the 29 strains of bacteroides fragilis produced heparinase. of 62 other bacteroides tested, only two of four strains of b ovatus, two of three strains of b thetaiotaomicron, and two of four strains of b uniformis were heparinase producers. none of the 48 strains of fusobacteria or seven strains of veillonella produced heparinase. the anaerobic cocci (19 peptococci and sev ... | 1987 | 3584480 |
| viability of lyophilized anaerobes in two media. | viability of 15 species of anaerobes was followed after freeze-drying and storage for 1 year. organisms maintained in a 12% sucrose concentration in chopped meat carbohydrate broth survived longer and maintained higher viability counts than those organisms in double-strength skim milk. | 1987 | 3568744 |
| increased resistance towards two systemic experimental infections by tetrachlorodecaoxygen anion complex. possible implications of cellular and humoral immunity. | the tetrachlorodecaoxygen anion complex (tcdo, oxoferin) given intravenously 1 h after intravenous infection of mice with candida albicans increased the host's resistance gradually in doses up to 3.1 mumol/kg body weight (b.w.). above this level, the stimulatory effect decreased, turning to an inhibition at a dose of 18.6 mumol/kg b.w. tcdo. repeated applications of the optimum single dose had no cumulative effect. in experimental infections with the strictly anaerobic peptostreptococcus interme ... | 1986 | 3566839 |
| comparative activity of metronidazole and tinidazole against clostridium difficile and peptostreptococcus anaerobius. | broth dilution mics of metronidazole against 38 strains of clostridium difficile (0.13 microgram/ml) and 11 strains of peptostreptococcus anaerobius (0.11 microgram/ml) were lower than those of tinidazole (0.16 and 0.17 microgram/ml, respectively). as molar concentrations the nitroimidazoles were equally active. the mics of the two drugs correlated positively, and the relative activity of tinidazole increased with decreasing susceptibility of both species. | 1987 | 3566248 |
| use of intravenous ciprofloxacin in difficult-to-treat infections. | intravenous ciprofloxacin was administered to 54 patients who were either critically ill or in whom oral administration was not possible. the 31 males and 23 females ranged in age from 20 to 89 years (mean, 53.2 +/- 17.8 years). patients had "difficult-to-treat" infections, i.e., respiratory infections (15), abscesses (four intraabdominal, three lung, two soft tissue, and one intrahepatic), deep soft tissue infections (10), chronic post-traumatic osteomyelitis in exacerbation (nine), upper urina ... | 1987 | 3555059 |
| pathogenicity and therapy of anaerobic bacteria in upper respiratory tract infections. | 1987 | 3547288 | |
| pseudofolliculitis barbae with keloids. | pseudofolliculitis barbae is a common cutaneous infection occurring in the bearded area of the face of black men. the infection is caused by ingrown hairs that produce an inflammatory foreign body reaction characterized by papules and pustules at the point of hair penetration that may result in permanent scarring, usually in grooved patterns, and occasionally in keloids. the purpose of this article is to describe the successful treatment of a patient with pseudofolliculitis with keloids that was ... | 1986 | 3540094 |
| [sensitivity of anaerobes to 8 antibiotics]. | we studied the susceptibility of 282 obligate anaerobes to 8 antibiotics. the strains were isolated from clinical specimens taken during 1983 and 1984. minimal inhibitory concentrations (mics) were determined using a microplate method for 245 strains and agar dilution for 33 bacteroides asaccharolyticus strains. tested strains were as follows: 85 bacteroides fragilis, 71 clostridium, 19 fusobacterium nucleatum, 35 peptostreptococcus, 39 bacteroides oralis and bacteroides bivius and 33 bacteroide ... | 1986 | 3534760 |
| [strict anaeroba in the endodontic region]. | 1986 | 3506338 | |
| intraventricular haemorrhage complicating a brain abscess. | intraventricular haemorrhage occurred in a patient with a parietal rim-enhancing mass on computed tomographic scan. at operation a brain abscess was identified and removed. peptostreptococcus and fusobacterium were isolated, possibly of dental origin. the possible sources of this intracranial bleeding are discussed. a neoplasm should not always be considered in the case of a cerebral ring-enhancing mass complicated with intracranial bleeding; in selected cases, brain abscess should be excluded t ... | 1987 | 3502181 |
| microbiological studies of tracheostomy site wounds. | specimens were obtained from 25 patients who developed tracheostomy site wound infections. aerobic bacteria only were isolated in 4 (16%) instances, anaerobic bacteria only in 2 (8%), and mixed aerobic and anaerobic isolates were recovered in 19 (76%). a total of 145 isolates (72 aerobes and 73 anaerobes) were recovered, an average of 5.8 isolates per specimen (2.9 aerobes and 2.9 anaerobes). the most frequently recovered isolates were peptostreptococcus sp., bacteroides sp., alpha-hemolytic str ... | 1987 | 3502089 |
| the intraocular environment and experimental anaerobic bacterial endophthalmitis. | anaerobic bacteria are prevalent in conjunctival flora but have not been adequately investigated as possible causes of endophthalmitis. the mean oxidation-reduction potential (eh) of the rabbit vitreous was found to be +25.1 mv, well within the limiting eh value of many anaerobes. there was an oxygen pressure gradient in the vitreous ranging from 2.1 mm hg immediately posterior to the lens to approximately 20 mm hg adjacent to the medullary ray. endophthalmitis was produced with pure cultures of ... | 1987 | 3499883 |
| [in vitro susceptibilities of brl 25000 (clavulanic acid-amoxicillin) against causative organisms in the field of obstetrics and gynecology]. | the in vitro susceptibilities of various causative organisms recently isolated from patients with genital infections to brl 25000 (a formulation with 2 parts of amoxicillin and 1 part of potassium clavulanate), amoxicillin (ampc), cefaclor (ccl), cephalexin (cex), cefadroxil (cdx) and cefroxadine (cxd) were determined. beta-lactamase-producing strains were detected by the nitrocefin disc method. frequencies of isolation of beta-lactamase producing strains of e. coli, k. pneumoniae and b. fragili ... | 1986 | 3488425 |
| in vitro activity of flurithromycin, a novel macrolide antibiotic. | flurithromycin is an (8,s)-8-fluoroerythromycin isolated from the fermentation broth of streptomyces erythraeus atcc 31772, a blocked mutant of a strain producer of erythromycin. its in vitro antibacterial activity has been determined on recent clinical isolates of respiratory pathogens. the range of mic for streptococcus pneumoniae and streptococcus beta-haemolyticus group a is from 0.0015 to 0.006 microgram/ml, for haemophilus influenzae from 0.012 to 0.4 microgram/ml, for staphylococcus aureu ... | 1986 | 3487389 |
| [peptostreptococcus sepsis complicating third molar pericoronitis]. | 1987 | 3483065 | |
| effects of extracellular products of a presumed gingival pathogen, the bacterium peptostreptococcus 84h14s, on cultured human fibroblasts and hela cells. | culture fluids from this microorganism, fibroblasts and hela cells contained potent factors which inhibited thymidine uptake in hela cells. the outcome of heating the culture fluid and fractionating it by gel filtration suggested that this was not due to bacterial hyaluronidase activity. purified peptostreptococcal hyaluronidase and several commercially-available mucopolysaccharidases also did not inhibit thymidine uptake. | 1987 | 3478031 |
| comparative serum bactericidal activity against test anaerobes in volunteers receiving imipenem, clindamycin, latamoxef and metronidazole. | ten healthy volunteers received on separate days the following regimens: imipenem 500 mg, clindamycin 600 mg, latamoxef 1 g, and metronidazole 500 mg. the antibiotics were given intravenously as an infusion over 15 min. blood samples were obtained before and 30 min, 1 and 6 h after the start of the infusion. serum bacteriostatic and bactericidal activities were measured against the following strains of strict anaerobes: two strains of bacteroides fragilis, one strain each of b. vulgatus, b. thet ... | 1987 | 3471750 |
| severe infections of the head and neck resulting from gas-forming organisms: report of case. | a case of severe infection of the head and neck associated with gas-forming organisms in a patient with fractures of the mandible is presented. selected aspects of antibiotic therapy are discussed. | 1987 | 3468169 |
| [fundamental and clinical studies of imipenem and imipenem/cilastatin sodium in the field of obstetrics and gynecology]. | fundamental and clinical studies of imipenem (mk-0787), a new type of carbapenem antibiotic, and mk-0787 combined with cilastatin sodium (mk-0791), a renal dipeptidase inhibitor, were carried out. the results obtained were as follows: mk-0787 500 mg alone or mk-0787 500 mg with mk-0791 500 mg was administered by intravenous drip infusion over 30 minutes. plasma levels of the drug were similar either following the administration of 500 mg of mk-0787 alone or 500 mg of mk-0787 with 500 mg of mk-07 ... | 1986 | 3463787 |
| anaerobic bacteraemia. | 1987 | 3449455 | |
| [studies on antimicrobial concentrations of flomoxef in serum, pelvic dead space exudate, and pelvic organs/tissues]. | to women undergoing radical and total hysterectomy, flomoxef (fmox, 6315-s) in a dose of 2 g was administered by intravenous drip infusion over 1 hour and drug concentrations in serum and pelvic dead space exudate as well as pelvic organs/tissues were determined over time. the following results were obtained: 1. serum concentrations of fmox after intravenous infusion showed the peak value of 92.86 +/- 17.05 micrograms/ml at the end of infusion and then gradually decreased to 29.00 +/- 10.49 micr ... | 1987 | 3444023 |
| bacteria in bile of patients with bile duct inflammation. | bile samples taken intraoperatively from 100 patients with three different bile system diseases were subjected to bacteriological analysis. statistically significant differences between the types of aerobic and anaerobic bacteria present in the bile were found. | 1987 | 3436318 |
| effect of streptococcus parvulus and peptostreptococcus magnus on cytotoxin levels of clostridium difficile in anaerobic continuous flow culture. | an anaerobic continuous flow (cf) culture method was used in order to study the effect of peptostreptococcus magnus and streptococcus parvulus, anaerobic gram-positive cocci which are members of intestinal bacterial flora, on growth and cytotoxin-activity of clostridium difficile. the growth- and the cytotoxin activity-patterns of c. difficile in an established cf culture of p. magnus were similar to those of c. difficile alone. on the other hand, in the mixed culture system of c. difficile and ... | 1987 | 3431487 |
| efficacy and safety of single-dose ceftizoxime vs. multiple-dose cefoxitin in preventing infection after vaginal hysterectomy. | the efficacy, safety and effect of a single, 1-g dose of ceftizoxime on the return of vaginal flora were compared to those of the standard regimen of three 2-g doses of cefoxitin for prophylaxis in 99 randomized women undergoing vaginal hysterectomy. thirty-four were studied in dallas and 65 in los angeles. surgical procedures were comparable for all the antibiotic groups, although proportionately more simple hysterectomies were performed in dallas. the patients received a povidone-iodine vagina ... | 1988 | 3422693 |
| induction of chronic arthritis in rats by cell wall fragments of anaerobic coccoid rods isolated from the faecal flora of patients with crohn's disease. | crohn's disease and ulcerative colitis are accompanied by seronegative arthritis in about one fifth of the cases. in the present study, cell wall fragments from major residents such as eubacterium, coprococcus and peptostreptococcus species, isolated from the faecal flora of patients with crohn's disease, were tested for properties to induce chronic arthritis in lewis rats. cell wall fragments from eubacterium contortum strains me44 and me47 were found to induce chronic arthritis; peptostreptoco ... | 1988 | 3410168 |
| presentation and management of neck abscess: a retrospective analysis. | a retrospective analysis of deep neck abscesses managed at the los angeles county-usc medical center was performed. fifty-one patients met the criteria and were reviewed as to presentation, etiology, location, and microbiology. hemolytic streptococci and anaerobic species, especially bacteroides and peptostreptococci, were the most common organisms isolated. intravenous drug abuse was the most common etiology, and was an important source of primary carotid space infection. this group was most co ... | 1988 | 3398666 |
| cecal and fecal bacterial flora of the mongolian gerbil and the chinchilla. | the mongolian gerbil is being increasingly used as a laboratory animal and as a pet. both chinchillas and gerbils are used as animal models for otitis media and other otic research. previously, only incomplete information was available regarding the indigenous bacterial flora of the lower intestinal tracts of these coprophagic animals. using the strict anaerobic methodology of the virginia polytechnic institute anaerobe laboratory, we studied the predominant bacterial flora of the cecum and feca ... | 1988 | 3389814 |
| recovery of anaerobic bacteria from clinical specimens in 12 years at two military hospitals. | examination of 15,844 clinical specimens submitted over 12 years (1973 to 1985) to the anaerobic microbiology laboratories in two military hospitals demonstrated the recovery of anaerobic bacteria in 4,458 (28.1%) specimens. the specimens yielded 6,557 anaerobic isolates (1.47 isolates per specimen). bacteroides spp. accounted for 43% of all isolates; anaerobic gram-positive cocci, 26%; clostridium spp., 7%; and fusobacterium spp., 4%. bacteroides spp. predominated in abscesses, obstetrical and ... | 1988 | 3384929 |
| enrichment and isolation of a ruminal bacterium with a very high specific activity of ammonia production. | when mixed ruminal bacteria were inoculated into semicontinuous cultures (25% transfer every other day) containing lactate, dulcitol, pectin, or xylose and trypticase (1 g/liter) as the sole nitrogen source, the specific activity of ammonia production increased. the greatest enrichment was observed with lactate and xylose, and in these cases the specific rate of ammonia production was eightfold higher than that of the ruminal fluid control (approximately 35 nmol of ammonia per mg of protein per ... | 1988 | 3377500 |
| metabolism of sennosides by human intestinal bacteria. | during the course of studies on the metabolism of sennosides by human intestinal bacteria, an enzyme which takes part in the reduction of sennosides and sennidins was originally isolated from peptostreptococcus intermedius. this enzyme catalyzed the electron transfer from nadh to fad, fmn or benzyl viologen, which reduced nonenzymatically sennosides and sennidins to 8-glucosyl-rhein anthrone and rhein anthrone, respectively. | 1988 | 3368516 |
| identification of gram-positive anaerobic cocci by use of systems for detecting pre-formed enzymes. | two systems for detecting pre-formed enzymes, rapid ana and a prototype system from api, were compared in a blind study for their ability to identify 69 gram-positive anaerobic cocci isolated from clinical specimens. both systems were able to identify peptostreptococcus anaerobius, ps. asaccharolyticus and ps. micros accurately without the need for further tests. the prototype api system identified all isolates of ps. magnus correctly, but the rapid ana system misidentified several isolates as p ... | 1988 | 3357195 |
| aerobic and anaerobic bacteriology of purulent nasopharyngitis in children. | cultures of aerobic and anaerobic bacteria were obtained from the inferior nasal meatus of 25 children with purulent nasopharyngitis and from 25 controls. microorganisms were isolated from all specimens. a total of 98 isolates (3.9 per patient), 45 aerobes (1.8 per patient) and 53 anaerobes (2.1 per patient), were isolated in patients with purulent nasopharyngitis. seventy-three isolates (2.9 per patient), 47 aerobes (1.9 per patient) and 26 anaerobes (1.0 per patient) were found in the controls ... | 1988 | 3356794 |
| omental pedicle graft in the management of infected ascending aortic prostheses. | two patients had mediastinal infections with chronic draining sinus tracts that involved a vascular prosthesis in the ascending aorta. in 1 patient, a false mycotic aneurysm developed and in the other, a beginning rupture of the proximal suture line. in both patients, the infection was cured by replacing the infected aortic prosthesis combined with wrapping the new prosthesis with a pedicled omental graft. an omental graft was used to protect the vascular prosthesis and minimize the risk of recu ... | 1987 | 3318738 |
| direct and indirect pathogenicity of anaerobic bacteria in respiratory tract infections in children. | bacteroides sp (bacteroides melaninogenicus, bacteroides oralis, and bacteroides fragilis), peptostreptococci, and fusobacteria are important pathogens in respiratory tract infections (rti). these organisms are often recovered mixed with other aerobic, facultative, and anaerobic bacteria. evidence supporting their virulence is provided by studies showing their synergistic potentials in mixed infections and their increased virulence when encapsulated. a recent increase in numbers of beta-lactamas ... | 1987 | 3318301 |
| the growth of oral bacteria on saliva. | the present experiments were aimed at studying the degradation of salivary glycoproteins by the oral microflora. to this end, s. sanguis i strain ny476 and s. sanguis ii (s. mitior) strain ny581 were grown continuously in human-whole saliva. under these conditions, the strains produced a variety of cell-associated hydrolytic activities, including glycosidases, exo- and endopeptidases, and esterases. s. sanguis ii generally exhibited higher levels of enzyme activity than did s. sanguis i, in part ... | 1987 | 3305628 |
| [activity of fusidic acid on strictly anaerobic bacteria]. | fusidic acid is a well known antimicrobial agent due to its narrow spectrum of activity against gram positive bacteria and especially staphylococci. therefore, it is after used preventively against bacterial infection in traumatology, but the susceptibility of anaerobic bacteria is not well known. we have studied, the in vitro activity of sodium fusidate against 147 strains of anaerobic bacteria. this antibiotic has a moderate activity against bacteroides, more significant against clostridium, p ... | 1987 | 3302863 |
| [revision of the taxonomy of the genera peptococcus and peptostreptococcus and a study on their identification system]. | 1987 | 3302346 | |
| [nonclostridial obligate anaerobes--the main causative agents of lung abscesses]. | the use of the anaerobic technique in bacteriological investigations has made it possible to establish the leading role of asporogenous anaerobes in the etiological structure of the causative agents of pulmonary abscesses. asporogenous anaerobes have been isolated from 93% of all examined patients, and in 54.4% of such patients these microorganisms have proved to be an independent etiological factor. among asporogenous anaerobes, the main causative agents of pulmonary abscesses have been found t ... | 1987 | 3296575 |
| microbiological and clinical aspects of aspiration pneumonia. | aspiration pneumonia is characterized by a pneumonitis in a dependent segment of the lung with typical necrosis or abscess-formation in the parenchyma. observed aspiration or predisposition to aspiration, cavitation or abscess formation, with or without empyema fluid and isolation of distinctive micro-organisms are important clues to the diagnosis. diagnostic procedures to collect anaerobic uncontaminated secretions are transtracheal aspiration, blood cultures, pleural fluid aspiration, fibreopt ... | 1988 | 3290185 |
| a multicenter comparative study of cefotetan once daily and cefoxitin thrice daily for the treatment of infections of the skin and superficial soft tissue. | to compare the effectiveness of cefotetan administered at 2 g once a day with cefoxitin at 1 or 2 g three times a day in the treatment of hospitalized patients with skin and superficial soft tissue infections, 194 patients from eight centers were enrolled in an open, randomized trial. most of the 104 evaluable patients in the cefotetan group and 50 in the cefoxitin group were young men with community-acquired, moderate or severe cellulitis, or abscesses of the upper and lower extremities caused ... | 1988 | 3287976 |
| [microbiology of samples from patients with periodontal pockets]. | a microbiologic study was carried out in 39 patients with periodontal affections, who were surgically treated. a formulary was drawn up for the collection of the following data: age, sex, criteria of russell periodontal index and microbiologic results. the contents of the periodontal pocket was collected at the time of the surgical procedure, and settled in assay tubes with culture medium to provide bacterial growth. the highest percentage of microorganisms were those of genus peptostreptococci, ... | 1988 | 3272438 |
| [aerobic and anaerobic bacterial flora of crural ulcers]. | in a group of 600 patients treated in the metropolitan dermatological hospital in warsaw bacteriological examination were carried out of swabs from the untreated crural ulcers. in 95% of these cultures growth of pathological aerobic organisms was obtained. coagulase-positive staphylococci (st. aureus) and gram-negative bacteria (pseudomonas aeruginosa, proteus vulgaris, enterobacter sp and e. coli) prevailed. in 27% of cases the cultured strains were resistant to the generally available antibiot ... | 1988 | 3268941 |
| clinical and laboratory findings in women with bacterial vaginosis and trichomoniasis versus controls. | we report comprehensively on the clinical and laboratory findings in 30 women with bacterial vaginosis (bv), 30 with vaginal trichomoniasis and 30 with normal secretions. women with trichomoniasis were more often divorced (chi 2 test, p much less than 0.001), more often complained of dyspareunia (chi 2 test, p less than 0.05), frequently had discharge present in the vaginal vestibule, and showed one or more signs of vaginitis in half the cases. a 'moth-eaten' cervix was seen in only four women ( ... | 1988 | 3260566 |
| bacteriology of periodontal disease in the cat. | subgingival plaque samples were obtained from 32 cats showing different stages of periodontal disease. correlations were sought between gingival index scores and the prevalence of various microbial groups, and between microbial populations found in sites designated as most-affected and least-affected within individual cats. the tendency with higher gingival index scores, and with the most-affected sites, was toward a microbial population composed to a greater extent of anaerobic gram-negative ro ... | 1988 | 3245794 |
| evaluation of a commercial latex test for clostridium difficile for reactivity with c. difficile and cross-reactions with other bacteria. | seventy-eight species of bacteria (739 isolates) were tested for reactivity with a commercial latex test for clostridium difficile. all noncytotoxic as well as cytotoxic strains of c. difficile reacted positively. immuno-specific cross-reactions were found only with c. sporogenes, proteolytic c. botulinum, and peptostreptococcus anaerobius. | 1988 | 3235677 |
| central nervous system infection associated with anaerobic bacteria in two dogs and two cats. | central nervous system (cns) infection caused by anaerobic bacteria (including bacteroides, fusobacterium, peptostreptococcus, and eubacterium) was diagnosed in two dogs and two cats. in one dog there was extensive meningomyeloencephalitis, presumably the result of hematogenous spread of bacteria from lung abscesses and bacterial endocarditis. subdural empyema of unknown origin was found in a second dog and two cats. clinical signs in all four animals included mental depression and focal neurolo ... | 1988 | 3230556 |
| empyema caused by kingella denitrificans and peptostreptococcus spp. in a patient with bronchogenic carcinoma. | empyema caused by kingella denitrificans and peptostreptococcus spp. was diagnosed in a patient with bronchogenic carcinoma. this appears to be the third report providing evidence of a pathogenic role for k. denitrificans, and the first concerning infection in the pleural space and in a patient with underlying immunosuppressive disease. k. denitrificans should be added to the list of fastidious gram-negative bacteria associated with opportunistic infections in the compromised host. | 1988 | 3229487 |
| presence of anaerobic bacteria in conjunctivitis associated with wearing contact lenses. | ten anaerobic bacterial species were found in conjunctival cultures obtained from six patients who wore contact lenses and developed conjunctivitis. in three instances the anaerobic bacteria were associated with facultative bacteria. the predominant anaerobic isolates were peptostreptococcus species (three isolates), bacteroides sp. (two), and fusobacterium sp. (two). it was the practice of five of the six patients to wet their lenses with saliva. it is recommended that a culture for anaerobes b ... | 1988 | 3207314 |
| infection of a prosthetic knee joint with peptostreptococcus magnus. | infection of a prosthetic knee joint with peptostreptococcus magnus in an immunosuppressed patient with rheumatoid arthritis is described. the organism is a skin commensal, generally thought to be of low pathogenicity; the difficulty in making the diagnosis is emphasised. | 1988 | 3196085 |
| tetracycline resistance and tetm in oral anaerobic bacteria and neisseria perflava-n. sicca. | tetracycline-resistant organisms isolated from six patients with periodontal disease included bacteroides spp., eubacterium spp., fusobacterium nucleatum, neisseria perflava-n. sicca, peptostreptococcus anaerobius, veillonella parvula, and facultative streptococci. all but the bacteroides spp. and eubacterium spp. hybridized with the tetm determinant. an additional 417 bacterial strains were screened, and 4% of both the oral streptococci and the fusobacterium spp. hybridized with the tetm probe. | 1988 | 3190205 |
| comparative activities of cefuroxime, amoxicillin-clavulanic acid, ciprofloxacin, enoxacin, and ofloxacin against aerobic and anaerobic bacteria isolated from bite wounds. | we studied the comparative in vitro activities of 10 oral antimicrobial agents against 147 aerobic and 61 anaerobic bacteria making up species in 13 genera (staphylococcus aureus, streptococci, eikenella corrodens, pasteurella multocida, haemophilus-actinobacillus spp., m-5, ef-4, moraxella spp., flavobacterium iib, bacteroides melaninogenicus, bacteroides spp., fusobacterium spp., and peptostreptococcus spp.) that were isolated from bite wounds. cefuroxime was generally greater than fourfold mo ... | 1988 | 3190202 |
| brain abscess from chronic odontogenic cause: report of case. | a case of a chronic odontogenic abscess that probably precipitated a frontopatrietal brain abscess by hematogenous spread has been presented. a thorough examination of the patient showed no other source of infection. peptostreptococcus sp was found as the common pathogen despite 6 days of broad-spectrum antibiotic therapy. this case emphasizes the important role of dentistry in medical diagnosis and treatment implemented in the hospital setting. | 1988 | 3183246 |
| preformed enzyme profiles of reference strains of gram-positive anaerobic cocci. | the preformed (constitutive) enzyme profiles of 30 type strains and reference strains of gram-positive anaerobic cocci were determined with two commercial systems, rapid ana and a prototype system from api. both systems identified peptostreptococcus anaerobius, ps. asaccharolyticus, ps. indolicus, ps. magnus and ps. micros accurately, except for one strain of ps. magnus misidentified as ps. micros by the rapid ana system. the indole-negative, butyrate-producing cocci (classified at present as ps ... | 1988 | 3172172 |
| semiquantitative culture results and pathogenic significance of obligate anaerobes in peritonsillar abscesses. | we studied the bacteria in consecutive peritonsillar abscesses using semiquantitation of the primary culture findings and correlated the results to clinical parameters. puncture-aspirated pus from 42 abscesses yielded 133 isolates. group a streptococci were isolated 10 times and, unlike other bacteria, were isolated 4 times in pure culture; other beta-hemolytic streptococci were found in 8 abscesses, and anaerobes were found in 28. the infections were polymicrobial, with two to seven bacteria in ... | 1988 | 3164314 |
| bactericidal effects of photoradiation therapy with hematoporphyrin derivative. | hematoporphyrin derivative (hpd) localizes selectively in malignant and rapidly metabolizing tissues and undergoes a cytotoxic reaction when exposed to light of a specific wavelength. hpd has been studied extensively with regard to the diagnosis and treatment of tumors but not with regard to bactericidal activity. this investigation assessed the effect of light-activated hpd on various microorganisms, on human polymorphonuclear leukocytes, and on the interactions of polymorphonuclear leukocytes ... | 1985 | 3155547 |
| characterization of cross-reactive proteins detected by culturette brand rapid latex test for clostridium difficile. | clostridium sporogenes, peptostreptococcus anaerobius, and bacteroides asaccharolyticus have been reported to react in the culturette brand rapid latex test (marion scientific, div. marion laboratories, inc., kansas city, mo.) for clostridium difficile. from the results of this study we showed that c. sporogenes and p. anaerobius produce a protein which is very similar biochemically and immunologically to the protein of c. difficile that is detected by the test. thus, the positive latex reaction ... | 1988 | 3128574 |
| protein l. a novel bacterial cell wall protein with affinity for ig l chains. | a novel ig-binding protein has been isolated from the surface of bacteria belonging to the anaerobic species peptococcus magnus. to solubilize the protein, peptococci were treated with different proteolytic enzymes (papain, pepsin, and trypsin) or with mutanolysin, a bacteriolytic agent known to digest the cell walls of streptococci. papain, trypsin, and mutanolysin all solubilized peptides showing affinity for radiolabeled human igg in western blot analysis. compared with papain and trypsin, mu ... | 1988 | 3125250 |
| the effect of carbon dioxide on the in vitro activity of erythromycin and ru-28965 against anaerobic bacteria. | the in vitro activity of erythromycin and ru-28965 (a novel macrolide antimicrobial with improved pharmacokinetics) was determined against a variety of anaerobic bacteria in anaerobic atmospheres with and without added carbon dioxide. minimum inhibitory concentrations (mic) were determined using an antimicrobial incorporation technique in wilkins-chalgren agar (oxoid, uk) containing saponinlysed horse blood to a final concentration of 10%. the inoculum used was approximately 10(4) colony forming ... | 1987 | 3113907 |
| [bacterial infection agents in hospitalized patients]. | during six months the pattern of microbial isolates has been analysed from 1492 urinary tract infections, from 1445 wound infections, from 451 bronchial secretions, from 3067 blood cultures, from 116 peritoneal swabs and from 39 cerebrospinal fluids. all the specimens investigated were taken from patients of surgical, neurosurgical, internal wards and two intensive care units. in total, the most frequent isolates were grampositive microorganisms like staphylococus aureus, straphylococcus epiderm ... | 1986 | 3107262 |
| long-term management of patients who have had urinary diversions into colon. | thirty-four patients with urinary-colonic diversions have been followed up for 13 to 41 years (mean 20.3). the commonest long-term complication was hyperchloraemic acidosis (50%). the most serious was neoplasm at the anastomotic site: benign lesions occurred in three patients and carcinomas in two (15%). staining for sialomucins in colonic biopsies adjacent to the anastomoses was positive in 17 of 19 patients. it has been suggested that this represents a pre-malignant change. analysis of faecal ... | 1986 | 3099879 |
| anaerobic bacteria in dentoalveolar abscesses. | the present study was initiated to determine the bacteriology of 40 orofacial abscesses of dental origin in patients who had taken antibiotics for several days. bacteria were isolated from all but 2 specimens. aerobic or facultative anaerobic bacteria were isolated in 21 cases, obligate anaerobic bacteria in 17 cases, whereas in 11 cases, polymicrobial growth was revealed. the average number of bacterial species was 2.1 per specimen. gram positive aerobic micro-organisms predominated, namely, st ... | 1986 | 3088157 |
| brain abscess after dilatation of esophageal stricture. | two children, below 15 years of age, developed brain abscesses after esophageal dilation. they were among 40 children treated for supratentorial brain abscesses during the past 10 years. pus culture of one of the abscesses was peptostreptococcus, which is a common oropharyngeal flora. clinicians should be aware of this complication since the prognosis is usually satisfactory after prompt treatment. | 1988 | 3077165 |
| anaerobic infections in the head and neck region. | anaerobic bacteria form the predominant flora of the oral cavity, outnumbering facultative organisms by 10-1,000: 1. the type of anaerobic bacteria and their concentration depend on the anatomical site and the degree of anaerobiosis in the different sites in the mouth. three groups of anaerobic bacteria inhabit the oral cavity; the strict anaerobes, the moderate anaerobes, and the microaerophilic group of organisms. the majority of anaerobic bacterial infections occurring in the region of the mo ... | 1988 | 3074469 |
| peptostreptococcus magnus septic arthritis--a report and review of the english literature. | we describe a 30-year-old female presenting with synovitis of the left 4th proximal interphalangeal joint. anaerobic cultures of the synovial membrane grew peptostreptococcus magnus. the synovitis resolved after a course of intravenous penicillin g. the role of the anaerobic bacterium peptostreptococcus magnus in joint infections is reviewed. | 1988 | 3060615 |
| [pharmacokinetic, bacteriological and clinical studies of cefuzonam in the field of obstetrics and gynecology. study group of cefuzonam in the field of obstetrics and gynecological infections]. | a multi-center open study was conducted to investigate cefuzonam (czon, l-105) regarding to its pharmacokinetic, bacteriological and clinical aspects in the field of obstetrics and gynecology with the participation of 31 medical institutions and the related facilities. the results are summarized as follows. 1. peak mics of czon for staphylococcus aureus, coagulase (-) staphylococci, escherichia coli, klebsiella pneumoniae, bacteroides fragilis group, peptostreptococcus spp. isolated from obstetr ... | 1988 | 3050195 |
| ampicillin/sulbactam versus metronidazole-gentamicin in the treatment of soft tissue pelvic infections. | the clinical efficacy and safety of ampicillin/sulbactam versus metronidazole-gentamicin were evaluated in a comparative, randomized, prospective study. forty-four patients were enrolled: 22 received the ampicillin/sulbactam regimen, and 22 received the metronidazole-gentamicin combination. there were 33 cases of severe acute pelvic inflammatory disease, two tuboovarian abscesses, five cases of endomyometritis, and two cases of posthysterectomy pelvic cellulitis. aerobic and anaerobic cultures f ... | 1987 | 3030109 |
| efficacy of sulbactam plus ampicillin in gynecologic infections. | the efficacy of sulbactam plus ampicillin in the treatment of various gynecologic infections was evaluated in 24 women (median age, 35 years). ten women had pelvic cellulitis plus vaginal cuff abscess; six, pyeloperitonitis; three, vaginal cuff abscess; three, surgical wound sepsis; one, tubo-ovarian abscess; and one, endometritis. surgical procedures preceding infection included abdominal hysterectomy, ovarian cyst removal, ectopic pregnancy, correction of cystocele, and uterine dilatation and ... | 1986 | 3026007 |