Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| comparative in vitro activity of cefditoren and other antimicrobials against enterobacteriaceae causing community-acquired uncomplicated urinary tract infections in women: a spanish nationwide multicenter study. | cefditoren is a third-generation orally administered cephalosporin with a broad spectrum of activity against gram-positive and gram-negative bacterial species. after an oral 400-mg single dose, the mean concentrations in urine are 186.5 mg/l at 2 to 4 h and 12.7 mg/l at 8 to 12 h, and it is a potential drug to be used in the treatment of urinary tract infection (uti). we performed a multicenter nationwide study in spain in order to determine the in vitro activity of cefditoren and other comparat ... | 2010 | 20542206 |
| in vitro antimicrobial, anthelmintic and cyclooxygenase-inhibitory activities and phytochemical analysis of leucosidea sericea. | leucosidea sericea is used as a vermifuge and in the treatment of ophthalmia by various tribes in southern african countries. | 2010 | 20542105 |
| hypermutability in clinical isolates of klebsiella pneumoniae is uncommon and is unrelated to ciprofloxacin resistance. | we investigated hypermutability in klebsiella pneumoniae and its association with ciprofloxacin resistance and mutations in the quinolone resistance-determining region (qrdr). sixty-four strains of k. pneumoniae isolated in london, uk, between 1995 and 2002 with widely differing ciprofloxacin minimum inhibitory concentrations (mics) and known gyra and parc sequences were tested for mutation frequencies by selection with rifampicin. only three hypermutable (frequency >or=10(-6)) strains were iden ... | 2010 | 20541915 |
| sepsis and cardiomyopathy as rare clinical manifestations of pheochromocytoma--two case report studies. | the clinical manifestation of pheochromocytomas is highly variable and can closely resemble numerous clinical conditions. here, we report on two cases of patients with pheochromocytoma, which manifested as sepsis or cardiomyopathy. the first patient initially presented with bacterial urosepsis due to klebsiella oxytoca. despite effective antibiotic therapy, the patient developed recurring fever accompanied by hypertension. the inconsistency between therapy-refractory hypertension and fever indic ... | 2010 | 20539976 |
| antibiotic susceptibility of intra-abdominal infection isolates from indian hospitals during 2008. | a total of 542 clinical isolates of aerobic gram-negative bacilli from intra-abdominal infections were collected during 2008 from seven hospitals in india participating in the study for monitoring antimicrobial resistance trends (smart). isolates were from various infection sources, the most common being gall bladder (30.1 %) and peritoneal fluid (31.5 %), and were mostly hospital-associated isolates (70.8 %) as compared to community-acquired (26.9 %). the most frequently isolated pathogens were ... | 2010 | 20538892 |
| risk factors for late onset gram-negative infections: a case-control study. | to determine the incidence, mortality and risk factors for neonatal late onset gram-negative sepsis and meningitis (logns). | 2011 | 20538712 |
| copper(ii) and nickel(ii) complexes of benzyloxybenzaldehyde-4-phenyl-3-thiosemicarbazone: synthesis, characterization and biological activity. | benzyloxybenzaldehyde-4-phenyl-3-thiosemicarbazone ligand (l) has been synthesized from benzyloxybenzaldehyde and 4-phenyl-3-thiosemicarbazide. complexes of this ligand with chlorides of cu(ii) and ni(ii) have been prepared. the structure of the ligand (l) is proposed based on elemental analysis, ir and (1)h nmr spectra. its complexes with cu(ii) and ni(ii) ions are characterized from the studies of electronic as well as epr spectra. on the basis of electronic and epr studies, rhombically distor ... | 2010 | 20538508 |
| solution structure and phospho-pmra recognition mode of pmrd from klebsiella pneumoniae. | in bacteria, the two-component system (tcs) is the most prevalent for sensing and transducing the environmental signals into the cell. in salmonella, the small basic protein pmrd is found to protect phospho-pmra and prolong the expression of pmra-activated genes. in contrast, escherichia coli pmrd fails to protect phospho-pmra. here, we show that klebsiella pneumoniae pmrd (kp-pmrd) can inhibit the dephosphrylation of phospho-pmra, and the interaction between kp-pmrd and the n-terminal receiver ... | 2010 | 20538060 |
| resistance to cephalosporins and carbapenems in gram-negative bacterial pathogens. | during the past 15 years, emergence and dissemination of beta-lactam resistance in nosocomial enterobacteriaceae, pseudomonas aeruginosa and acinetobacter baumannii, became a serious problem worldwide. especially the increasing resistance to 3rd and 4th generation cephalosporins and carbapenems is of particular concern. gram-negative bacteria pursue various molecular strategies for development of resistance to these antibiotics: (a) generation of extended-spectrum beta-lactamases (esbl) accordin ... | 2010 | 20537585 |
| new quinoline derivatives: synthesis and investigation of antibacterial and antituberculosis properties. | four new series of quinoline derivatives were synthesized starting from 2-trifluoromethyl aniline through multi-step reactions. in the reaction sequence, substituted aniline was cyclized to 4-hydroxy quinoline 1, which was then transformed to 4-chloro-2,8-bis(trifluoromethyl)quinoline 2. the key scaffold 4-hydrazinyl-2,8-bis(trifluoromethyl)quinoline 3, obtained from the compound 2, was successfully converted to target quinoline derivatives, viz. hydrazones 4a-t, ureas 5a-e, thioureas 6a-c and p ... | 2010 | 20537437 |
| the association between antibiotic use and resistance: the role of secondary antibiotics. | using susceptibility rates of pseudomonas aeruginosa, escherichia coli, klebsiella pneumoniae, and enterobacter cloacae over time as markers, we assessed the significance of the change of susceptibility rates to imipenem, ceftriaxone, cefepime, piperacillin/tazobactam, and ciprofloxacin over time and the relationship to antibiotic use for the period 2000-2006. antibiotic use-susceptibility relationships were assessed using longitudinal regression analysis. the variables "time" and define daily d ... | 2010 | 20535624 |
| the effect of hydrolysis degree on the properties of antibacterial polymeric films based on poly(vinyl alcohol) and zinc sulphate for biomedical applications. | fully and partially hydrolyzed poly(vinyl alcohol) (pva) was modified with zinc sulphate in the concentration range from 0 to 9 wt% of recalculated zinc content using the solvent cast technique. the resulting polymeric films were characterized by optical microscopy, stress-strain analysis, differential scanning calorimetry and fourier transform infrared spectroscopy (ft-ir-atr). in addition, agar diffusion test and dilution and spread plate technique were used for determination of antibacterial ... | 2010 | 20534194 |
| mutagenesis of klebsiella aerogenes ureg to probe nickel binding and interactions with other urease-related proteins. | ureg is a gtpase required for assembly of the nickel-containing active site of urease. herein, a strep-tagged klebsiella aerogenes ureg (ureg(str)) and selected site-directed variants of ureg(str) were constructed for studying the in vivo effects on urease activation in recombinant escherichia coli cells, characterizing properties of the purified proteins, and analysis of in vivo and in vitro protein-protein interactions. whereas the strep tag had no effect on ureg's ability to activate urease, ... | 2010 | 20533838 |
| warfarin-induced skin necrosis in hiv-1-infected patients with tuberculosis and venous thrombosis. | at the turn of the century, only 300 cases of warfarin-induced skin necrosis (wisn) had been reported. wisn is a rare but potentially fatal complication of warfarin therapy. there are no published reports of wisn occurring in patients with hiv-1 infection or tuberculosis (tb). | 2010 | 20529438 |
| carbapenem-nonsusceptible strains of klebsiella pneumoniae producing shv-5 and/or dha-1 beta-lactamases in a czech hospital. | resistance to carbapenems in enterobacteria is mediated by the production of several types of carbapenemases or by the decreased permeability of the outer membrane, combined with the expression of extended-spectrum beta-lactamases (esbls) or ampc-like cephalosporinases. the objective of this study was to characterize carbapenem-nonsusceptible (c-ns) isolates of klebsiella pneumoniae in the university hospital in plzen (czech republic) and compare them with carbapenem-susceptible (c-s) k. pneumon ... | 2010 | 20528936 |
| detection of a common plasmid carrying blakpc-2 in enterobacteriaceae isolates from distinct cities in china. | four isolates of klebsiella pneumoniae and one isolate of enterobacter cloacae exhibiting resistance to most β-lactam antibiotics, including oxyimino-cephalosporins and carbapenems, were obtained from different patients among four hospitals in china. pulsed-field gel electrophoresis demonstrated that all the k. pneumoniae isolates belonged to two clone patterns. multilocus sequence typing showed that the four isolates of k. pneumoniae belonged to two sequence types: st 23 and st 351. conjugation ... | 2010 | 20528100 |
| [clinical assessment of novel chromid esbl agar plates for detection of esbl producers in the family enterobacteriaceae]. | extended-spectrum beta-lactamase (esbl)-producers in the family enterobacteriaceae are recognized worldwide as nosocomial pathogens, however it is difficult to screen them in the routine laboratory processing. chromid esbl agar newly developed for screening esbl-producing enterobacteriaceae was released in japan in april, 2007. we evaluated the clinical assessment of chromid esbl agar in routine microbiology laboratory. the 47 strains investigated were clinical isolates belonging to the family e ... | 2009 | 20528091 |
| isolation and characterization of klebsiella pneumoniae specific bacteriophages from sewage samples. | five bacteriophages (kpn5, kpn12, kpn13, kpn17 and kpn22), each having specificity against klebsiella pneumoniae strain b5055, were isolated from sewage samples and characterized in terms of growth characteristics, genetic material, morphology and structural proteins. adsorption rate as well as single step growth curve experiments showed variation among phages. restriction enzyme digestion of dna confirmed the presence of double stranded dna as well as the heterogeneous nature of genetic materia ... | 2010 | 20526833 |
| indole-3-acetic acid (iaa) production in symbiotic and non-symbiotic nitrogen-fixing bacteria and its optimization by taguchi design. | production of indole-3-acetic acid (iaa) in 35 different symbiotic and non-symbiotic nitrogen-fixing bacteria strains isolated from soil and plant roots was studied and assayed by chromatography and colorimetric methods. these bacteria included agrobacterium, paenibacillus, rhizobium, klebsiella oxytoca, and azotobacter. the best general medium and synergism effects of isolates for iaa production were investigated. effects of different variables containing physical parameters and key media compo ... | 2010 | 20526603 |
| antibacterial activity of zno nanoparticles prepared via non-hydrolytic solution route. | the antibacterial activity of zno nanoparticles has been investigated and presented in this paper. nanoparticles were prepared via non-hydrolytic solution process using zinc acetate di-hydrate (zn(ch(3)coo)(2).2h(2)o) and aniline (c(6)h(5)nh(2)) in 6 h refluxing at approximately 65 degrees c. in the presence of four pathogens such as staphylococcus aureus, escherichia coli, salmonella typhimurium, and klebsiella pneumoniae, the antibacterial study of zinc oxide nanoparticles were observed. the a ... | 2010 | 20526594 |
| antibiotic resistance patterns and detection of bladha-1 in salmonella species isolates from chicken farms in south korea. | fifteen nonrepetitive ampicillin-resistant salmonella spp. were identified among 91 salmonella sp. isolates during nationwide surveillance of salmonella in waste from 131 chicken farms during 2006 and 2007. additional phenotyping and genetic characterization of these 15 isolates by using indicator cephalosporins demonstrated that resistance to ampicillin and reduced susceptibility to cefoxitin in three isolates was caused by tem-1 and dha-1 beta-lactamases. plasmid profiling and southern blot an ... | 2010 | 20525869 |
| [immunization and bacterial pathogens in the oropharynx as risk factors for alopecia areata]. | alopecia areata is an autoimmune inflammatory disease affecting the hair follicles. researchers are currently interested in whether the presence of bacterial pathogens and/or a history of immunization can trigger an autoimmune response in patients who are genetically predisposed. | 2010 | 20525487 |
| development of high-level carbapenem resistance in klebsiella pneumoniae among patients with prolonged hospitalization and carbapenem exposure. | an increasing incidence of carbapenem-resistant klebsiella pneumoniae (crkp) infections has been reported worldwide. the aim of this study was to investigate the mechanism underlying carbapenem resistance and its relationship to antibiotic exposure. sixteen isolates with various carbapenem susceptibilities recovered from five patients between 2003 and 2006 were subjected to molecular study. the medical records of the patients were also reviewed. all of the patients were admitted for complicated ... | 2010 | 20524901 |
| bacterial pneumonia following cytotoxic chemotherapy for lung cancer: clinical features, treatment outcome and prognostic factors. | data regarding treatment outcomes and prognosis in pneumonia that occurs after lung cancer chemotherapy are lacking. we performed a retrospective study of 84 patients with clinically suspected bacterial pneumonia after cytotoxic chemotherapy for lung cancer. small cell carcinoma was the most common histological type (36.9%, n = 31), followed by squamous cell carcinoma (35.7%, n = 30) and adenocarcinoma (21.4%, n = 18). the most frequent pathogen was streptococcus pneumoniae (n = 14), followed by ... | 2010 | 20524784 |
| pattern of pathogens and their sensitivity isolated from superficial surgical site infections in a tertiary care hospital. | infection is an important cause of morbidity and mortality in surgical patients. rapidly emerging nosocomial pathogens and the problem of multi-drug resistance necessitates periodic review of isolation patterns and sensitivity in surgical practice. surgical site infections (ssi) are defined as an infections that occurs at the incision site within thirty days after surgery. objectives of the study were to determine the pattern of pathogens involved and their antibiotic sensitivity isolated from s ... | 2009 | 20524476 |
| [etiologic factors in urinary tract infection investigated in ambulatory setting. community-acquired urinary tract infection: etiologic aspects and antibiotic resistance]. | urine bacteriological examination is one of the most frequently asked for examinations, in ambulatory as well as in hospitals, regarding specialty prophyle. the present study comprises a group of 3971 pacients that were sent to the laboratory for uroculture and showed a percentage of only 21.85% significant urocultures--the etiological groups most frequently isolated being gram-negative bacilli--96.05%, respectively escherichia sp. 76.95%, klebsiella sp. 14.68%, proteus sp. 4.66%. out of the gra ... | 2009 | 20524391 |
| asymmetrical distribution of the second messenger c-di-gmp upon bacterial cell division. | the bacterial second messenger cyclic diguanosine monophosphate (c-di-gmp) regulates cellular motility and the synthesis of organelles and molecules that promote adhesion to a variety of biological and nonbiological surfaces. these properties likely require tight spatial and temporal regulation of c-di-gmp concentration. we have developed genetically encoded fluorescence resonance energy transfer (fret)-based biosensors to monitor c-di-gmp concentrations within single bacterial cells by microsco ... | 2010 | 20522779 |
| detection of the new metallo-beta-lactamase vim-19 along with kpc-2, cmy-2 and ctx-m-15 in klebsiella pneumoniae. | to report the identification of the metallo-beta-lactamase (mbl) variant vim-19 in a klebsiella pneumoniae clinical strain co-producing kpc-2 carbapenemase, cmy-2 cephalosporinase and ctx-m-15 extended-spectrum beta-lactamase. | 2010 | 20522444 |
| antimicrobial susceptibility of gram-negative nonurinary bacteria to fosfomycin and other antimicrobials. | fosfomycin is an antimicrobial commonly used in uncomplicated urinary tract infections. the microbiological effectiveness of fosfomycin against nonurinary gram-negative isolates has not been widely investigated. the aim of this study was to evaluate the in vitro activity of fosfomycin against gram-negative nonurinary isolates in a region of greece where considerable antimicrobial resistance has been detected. | 2010 | 20521939 |
| activity of doripenem against extended-spectrum beta-lactamase-producing enterobacteriaceae and pseudomonas aeruginosa isolates. | the in vitro activity of doripenem was evaluated against a recent collection of extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae and pseudomonas aeruginosa isolates (201 esbl-producing enterobacteriaceae [153 escherichia coli and 48 klebsiella pneumoniae] and 201 p. aeruginosa). comparator agents included amikacin, tobramycin, ciprofloxacin, cefepime, cefotaxime, ceftazidime piperacillin-tazobactam, imipenem, and meropenem. both doripenem and meropenem inhibited 100% of the e ... | 2010 | 20521156 |
| evidence to support the therapeutic potential of bacteriophage kpn5 in burn wound infection caused by klebsiella pneumoniae in balb/c mice. | the emergence of antibiotic-resistant bacterial strains is one of the most critical problems of modern medicine. bacteriophages have been suggested as an alternative therapeutic agent for such bacterial infections. in the present study, we examined the therapeutic potential of phage kpn5 in the treatment of klebsiella pneumoniae b5055-induced burn wound infection in a mouse model. an experimental model of contact burn wound infection was established in mice employing k. pneumoniae b5055 to asses ... | 2010 | 20519918 |
| rapid reporting of urine culture results: impact of the uro-quick screening system. | this study evaluated the impact of the uro-quick (uq) screening system (alifax, italy) for a rapid and accurate reporting of urine cultures, and whether it can provide bacterial yield to be used in identification and susceptibility testing. a total of 1480 urine samples collected between october 2006 and july 2008 were tested by conventional culture (cc) methods and uq simultaneously. sediments of positive uq vials were used as bacterial yields for identification and susceptibility testing proce ... | 2010 | 20518276 |
| the impact of fluoroquinolones use on antibiotic resistance in an intensive care burn department. | fluoroquinolones (fq) use has been identified as a risk factor for colonization and infection to methicillin resistant staphylococcus aureus(mrsa), pseudomonas aeruginosae multiresistant(pmr) , acinetobacter multiresistant (amr) and multidrug resistant bacteria(mdrb). | 2010 | 20517823 |
| migrated foreign body liver abscess: illustrative case report, systematic review, and proposed diagnostic algorithm. | pyogenic liver abscess is a severe condition and a therapeutic challenge. treatment failure may be due to an unrecognized ingested foreign body that migrated from the gastrointestinal tract. there has recently been a marked increase in the number of reported cases of this condition, but initial misdiagnosis as cryptogenic liver abscess still occurs in the majority of cases. we conducted the current study to characterize this entity and provide a diagnostic strategy applicable worldwide. to this ... | 2010 | 20517180 |
| a mimicry of melioidosis by klebsiella ozaenae infection. | klebsiella ozaenae is a gram negative bacillus. it has been described as a colonizer of oral and nasopharyngeal mucosa and is a cause of atrophic rhinitis. klebsiella ozaenae has seldom been isolated from serious infections. however, several reports have stated that klebsiella ozaenae may cause invasive infections and even mortality. we report a 55-year-old man with klebsiella ozaenae infection causing abscesses involving the right eye and left kidney and possibly also in the brain, lungs and pr ... | 2009 | 20514860 |
| most frequent causes of urinary tract infections in children. | to determine the most frequent causes of urinary tract infection (uti) amongst children according to gender and age. | 2010 | 20514772 |
| emergence of bla kpc-3-tn4401a associated with a pkpn3/4-like plasmid within st384 and st388 klebsiella pneumoniae clones in spain. | kpc carbapenemase-producing klebsiella pneumoniae isolates have been increasingly detected in europe. we report the first kpc-producing isolates characterized in madrid, spain. | 2010 | 20513703 |
| carbapenem-resistant acinetobacter baumannii and klebsiella pneumoniae across a hospital system: impact of post-acute care facilities on dissemination. | resistance to carbapenems among acinetobacter baumannii and klebsiella pneumoniae presents a serious therapeutic and infection control challenge. we describe the epidemiology and genetic basis of carbapenem resistance in a. baumannii and k. pneumoniae in a six-hospital healthcare system in northeast ohio. | 2010 | 20513702 |
| susceptibility of klebsiella spp. to tigecycline and other selected antibiotics. | tigecycline is a new glycylcycline with broad-spectrum activity. among these new agents, tigecycline is unique in generally having good activity against gram-negative bacteria. tigecycline has been approved for the treatment of complicated intra-abdominal infections and complicated skin and skin structure infections. tigecycline had good activity against most esbl-producing enterobacteriaceae and may be a therapeutic alternative to carbapenems in some infections caused by esbl-producing isolates ... | 2010 | 20512088 |
| role of mrkj, a phosphodiesterase, in type 3 fimbrial expression and biofilm formation in klebsiella pneumoniae. | klebsiella pneumoniae is an opportunistic pathogen that has been shown to adhere to human extracellular matrices using the type 3 fimbriae. introduction of plasmids carrying genes known to alter intracellular cyclic-di-gmp pools in vibrio parahaemolyticus revealed that these genes also altered type 3 fimbrial surface expression in k. pneumoniae. immediately adjacent to the type 3 fimbrial gene cluster is a gene, mrkj, that is related to a family of bacterial genes encoding phosphodiesterases. we ... | 2010 | 20511505 |
| the ongoing challenge of acquired carbapenemases: a hospital outbreak of klebsiella pneumoniae simultaneously producing vim-1 and kpc-2. | 2010 | 20510588 | |
| extended spectrum beta-lactamase producing escherichia coli and klebsiella pneumoniae isolated in a rural hospital. | extended spectrum beta-lactamase (esbl) producing strains pose greatest therapeutic challenge and have been reported as emerging pathogens causing nosocomial infection. the present study was undertaken to detect the esbl producing esch coli and klebsiella pneumoniae strains, which were screened to detect esbl production. a total number of 320 e. coli and klebsiella pneumoniae strains were processed in the microbiology department. antibiotic sensitivity test with ciprofloxacin, amikacin, cefotaxi ... | 2009 | 20509468 |
| transfer of carbapenem-resistant plasmid from klebsiella pneumoniae st258 to escherichia coli in patient. | klebsiella pneumoniae carbapenemase (kpc) 3-producing escherichia coli was isolated from a carrier of kpc-3-producing k. pneumoniae. the kpc-3 plasmid was identical in isolates of both species. the patient's gut flora contained a carbapenem-susceptible e. coli strain isogenic with the kpc-3-producing isolate, which suggests horizontal interspecies plasmid transfer. | 2010 | 20507761 |
| spread of oxa-48-mediated resistance to carbapenems in lebanese klebsiella pneumoniae and escherichia coli that produce extended spectrum beta-lactamase. | 2010 | 20507701 | |
| [change in distribution of pathogens and nosocomial antibiotic resistant gram-negative bacilli infection in intensive care units one month after an earthquake]. | to investigate the change in distribution of pathogens and nosocomial antibiotic resistant gram-negative bacilli infection in intensive care units one month after an earthquake. | 2010 | 20506662 |
| clinical and microbiological characteristics of community-acquired thoracic empyema or complicated parapneumonic effusion caused by klebsiella pneumoniae in taiwan. | klebsiella pneumoniae is the major cause of community-acquired pyogenic infections in taiwan and is becoming an increasing problem in acute thoracic empyema. this study evaluated the clinical and microbiological characteristics of community-acquired thoracic empyema or complicated parapneumonic effusion caused by k. pneumoniae in taiwanese adults treated during the period 2001-2008 at a tertiary medical center. all clinical isolates were examined for capsular serotypes k1/k2, and pulsed-field ge ... | 2010 | 20505967 |
| predictors, treatment, and outcomes of non-pseudomonas gram-negative peritonitis. | non-pseudomonas gram-negative (npgn) peritonitis is a frequent, serious complication of peritoneal dialysis; however, previous reports have been limited to small, single-center studies. to gain insight on the frequency, predictors, treatment, and outcomes of npgn peritonitis, we analyzed data in the anzdata registry of all adult australian peritoneal dialysis patients over a 39-month period using multivariate logistic and multilevel poisson regressions. there were 837 episodes of npgn peritoniti ... | 2010 | 20505659 |
| characteristics of meropenem heteroresistance in klebsiella pneumoniae carbapenemase (kpc)-producing clinical isolates of k. pneumoniae. | meropenem heteroresistance was investigated in six apparently meropenem-susceptible, klebsiella pneumoniae carbapenemase (kpc)-producing k. pneumoniae (kpc-kp) clinical isolates, compared with that in carbapenemase-negative, meropenem-susceptible controls. in population analyses, the kpc-kp isolates grew at meropenem concentrations of 64 to 256 microg/ml. heteroresistant colonies had significantly elevated expression of the bla(kpc) gene compared with the native populations but did not retain he ... | 2010 | 20504985 |
| antimicrobial resistant bacteria among health care workers in intensive care units at ain shams university hospitals. | fifty hcws in icus of internal medicine, chest, neonatology and burn were included in prospective cohort study. collection of nasal, hand and rectal swabs, proper biochemical identification, culture media and antibiotic sensitivity tests were used to detect methicillin-resistant staphylococcus aureus (mrsa); vancomycin-resistant enterococci (vre) & extended spectrum beta-lactamase producing gram -ve bacilli (esbls). s. aureus was isolated from 34% of hcws; 28% were nasal carriers, 4% were hand c ... | 2010 | 20503587 |
| pyogenic liver abscess: differences in etiology and treatment in southeast asia and central europe. | knowledge of etiology and timely treatment of underlying causes, when possible, play an important role in the successful therapy of patients with pyogenic liver abscess (pla). recent publications from central europe and southeast asia hint at considerable differences in etiology. in this article, we aim to elaborate these differences and their therapeutic implications. apart from some special types of pla that are comparable in southeast asia and central europe (such as posttraumatic or postproc ... | 2010 | 20503444 |
| antimicrobial activity of hemidesmus indicus, ficus bengalensis and pterocarpus marsupium roxb. | the antimicrobial activity of hemidesmus indicus, ficus bengalensis and pterocarpus marsupium roxb was evaluated against pathogenic bacteria stahylococcus aureus, pseudomonas aeruginosa and klebsiella pneumonia in an in vitro condition. aqueous extracts from roots of h. indicus and barks of f. bengalensis and p. marspium roxb were tested for antimicrobial activity using the zone of inhibition method and also screened for phytochemicals. the aqueous extract of p. marsupium roxb inhibited growth o ... | 2009 | 20502584 |
| antibiotic pigment from desert soil actinomycetes; biological activity, purification and chemical screening. | an actinomycete strain, streptomyces hygroscopicus subsp. ossamyceticus (strain d10) was isolated from thar desert soil, rajasthan during the year 2006 and found to produce a yellow color pigment with antibiotic activity. crude pigment was produced from strain d10 by solid state fermentation using wheat bran medium followed by extraction with ethyl acetate. the antimicrobial activity of the crude pigment was evaluated against drug resistant pathogens such as methicillin-resistant staphylococcus ... | 2009 | 20502566 |
| synthesis and pharmacological evaluation of schiff bases of 4-(2-aminophenyl)-morpholines. | in the present study, a novel series of 4-(2-aminophenyl)morpholines were synthesized and characterized by ir, (1)h-nmr, (13)c nmr and mass spectral analysis. the synthesized compounds were screened for analgesic (100 and 200 mg/kg), antiinflammatory (200 and 400 mg/kg), antibacterial (bacillus subtilis, bacillus cereus, staphylococcus epidermidis, staphylococcus aureus, klebsiella pneumoniae, pseudomonas aeruginosa and escherichia coli) and antifungal (candida albicans and aspergillus niger) ac ... | 2009 | 20502549 |
| [antibacterial activity of recombinant thanatin expressed by e.coli er2566]. | to express antibacterial peptide thanatin in the prokaryotic expression system and test its antibacterial activity. | 2010 | 20501392 |
| may chlamydia trachomatis be an aetiological agent of chronic prostatic infection? | chlamydia trachomatis infection is the most common sexually transmitted bacterial disease. the objective of this study was to establish the presence/absence of c. trachomatis in 98 patients with chronic complaints about the prostate and to evaluate the role of this bacterium in the inflammation of the gland. we performed culture and microscopical examination of pre-massage/post-massage urine and expressed prostatic secretions (eps). in all cases, culture on mccoy cells and polymerase chain react ... | 2010 | 20500746 |
| klebsiella pneumoniae-associated vertebral osteomyelitis after laparoscopic cholecystectomy. | we report a case of a patient who underwent elective laparoscopic cholecystectomy and subsequently developed klebsiella pneumoniae-associated vertebral osteomyelitis after 2 months. development of vertebral osteomyelitis after laparoscopic cholecystectomy has never been reported previously. diagnosis was made via magnetic resonance imaging. the patient was successfully treated with intravenous antibiotics and had a complete recovery with no neurologic sequelae. | 2010 | 20499776 |
| [occurrence of resistant enterobacteriaceae isolated from carriers and infections in pediatric wards of a polish reference hospital]. | study was carried out from june to november 2008 in the group of newborn babies hospitalized at the highly specialized hospital. twenty-six clinical isolates of esbl-positive rods were collected from 24 patients. infections incidence was confirmed on the level 3.4/1000 patientdays (pds), among infection dominated blood infection (41%) and pneumonia (31%). all isolates were analyzed for the presence of genes of the resistance (bla)shv, (bla)tem i (bla)ctx-m by the multiplex pcr amplification. iso ... | 2010 | 20499660 |
| expression of 1,3-propanediol oxidoreductase and its isoenzyme in klebsiella pneumoniae for bioconversion of glycerol into 1,3-propanediol. | in the klebsiella pneumoniae reduction pathway for 1,3-propanediol (1,3-pd) synthesis, glycerol is first dehydrated to 3-hydroxypropionaldehyde (3-hpa) and then reduced to 1,3-pd with nadh consumption. rapid conversion of 3-hpa to 1,3-pd is one of the ways to improve the yield of 1,3-pd from glycerol and to avoid 3-hpa accumulation, which depends on enzyme activity of the reaction and the amount of reducing equivalents available from the oxidative pathway of glycerol. in the present study, the y ... | 2010 | 20499228 |
| cadc regulates cad and tdc operons in response to gastrointestinal stresses and enhances intestinal colonization of klebsiella pneumoniae. | to explore the mechanisms that enable klebsiella pneumoniae to survive in the gastrointestinal tract, we characterized the roles of the cad and tdc operons during the bacterial response to acid and bile stress. | 2010 | 20497056 |
| volatiles emitted from eight wound-isolated bacteria differentially attract gravid screwworms (diptera: calliphoridae) to oviposit. | bovine blood inoculated with bacteria isolated from screwworm [cochliomyia hominivorax (coquerel) (diptera: calliphoridae)]-infested animal wounds was tested as an attractant for oviposition for gravid screwworms. eight species of gram-negative coliform (enterobacteriaceae) bacteria mixed with bovine blood singly or all species combined and incubated for various times produced volatiles that attracted gravid flies in a cage bioassay in varying numbers. in 15-min duration tests, volatiles from fi ... | 2010 | 20496582 |
| positive culture for klebsiella pneumoniae in relevant sputum samples as a predictor of rapidly fatal outcome in septic patients at medical intensive care units. | sixty-five patients with main diagnosis of sepsis, who were directly admitted to the emergency department (ed) and had fatal outcomes after transfer to the medical intensive care units (micu), were included. patients who died within 48 hours of micu transfer were defined as having rapidly fatal outcomes (rfo). the following clinical variables, including diagnosis of infection source; results of blood, sputum, and urine cultures; management for sepsis in the ed and micu and survival time, were an ... | 2010 | 20495991 |
| quinazoline derivatives are efficient chemosensitizers of antibiotic activity in enterobacter aerogenes, klebsiella pneumoniae and pseudomonas aeruginosa resistant strains. | amongst the three series of quinazoline derivatives synthesised and studied in this work, some molecules increase the antibiotic susceptibility of gram-negative bacteria presenting multidrug-resistant phenotypes. n-alkyl compounds induced an increase in the activity of chloramphenicol, nalidixic acid and sparfloxacin, which are substrates of the acrab-tolc and mexab-oprm efflux pumps in clinical isolates. these molecules are able to increase the intracellular concentration of chloramphenicol in ... | 2010 | 20494558 |
| kpc-2 producing klebsiella pneumoniae and escherichia coli co-infection in a catheter-related infection. | we describe the first report of simultaneous blood infection with kpc-2 producing klebsiella pneumoniae and escherichia coli in a brazilian patient. we highlight the importance of implementing efficient infection control measures to limit the spread of these phenotypes in a hospital setting. | 2011 | 20491828 |
| cadmium chloride exhibits a profound toxic effect on bacterial microflora of the mice gastrointestinal tract. | cadmium (cd²(+)), a naturally occurring heavy metal, is an important environmental pollutant and a potent toxicant to bacteria. the gastrointestinal (gi) tract microflora has a marked capacity to cope with the increased load of ingested metals. however, heavy metals may have harmful effects on git microflora. under the conditions of experimental exposure to cadmium, changes in the population of intestinal microflora in healthy mice were examined. five experimental groups received 23 to 50 mg kg⁻ ... | 2011 | 20488844 |
| termination of a 4-month serial klebsiella pneumoniae septicemia in a diabetic woman after aneurysmectomy in conjunction with antimicrobial therapy. | a diabetic woman suffered from deep neck infection, endophthalmitis, urinary tract infection, and mycotic aneurysm associated klebsiella pneumoniae bacteremia for 4 months. aneurysmectomy and antibiotic therapy terminated recurrent k pneumoniae sepsis suggestive of removal of the pathogen niche in an artery, which served as the root of serial infections. the dna fingerprints of k pneumoniae isolates indicated that the same strain k pneumoniae caused all the infection episodes. the case is report ... | 2010 | 20488656 |
| acute pyelonephritis can have serious complications. | urinary tract infection (uti) may predominantly involve the lower urinary tract, i.e. acute cystitis, or upper urinary tract consisting of the renal pelvis and kidney,, i.e. acute pyelonephritis the incidence of acute pyelonephritis is higher in young women than in men but the incidence in men over 65 is similar to that in older women. women have up to a 10% risk of recurrent acute pyelonephritis in the year following a first acute episode. the equivalent risk in men is 6%. acute pyelonephritis ... | 2010 | 20486480 |
| comparison of meropenem mics and susceptibilities for carbapenemase-producing klebsiella pneumoniae isolates by various testing methods. | we describe the levels of agreement between broth microdilution, etest, vitek 2, sensititre, and microscan methods to accurately define the meropenem mic and categorical interpretation of susceptibility against carbapenemase-producing klebsiella pneumoniae (kpc). a total of 46 clinical k. pneumoniae isolates with kpc genotypes, all modified hodge test and bla(kpc) positive, collected from two hospitals in ny were included. results obtained by each method were compared with those from broth micro ... | 2010 | 20484603 |
| evaluation of microbial contamination associated with different preparation methods for neonatal intravenous fat emulsion infusion. | microbial contamination associated with different methods of neonatal intravenous fat emulsion (ivfe) preparation and delivery was evaluated. | 2010 | 20484215 |
| screening for genes involved in klebsiella pneumoniae biofilm formation using a fosmid library. | klebsiella pneumoniae is a well-known opportunistic pathogen, often causing catheter-associated urinary tract infections. biofilm formation on the catheter surfaces is an important step in the development of these infections. to identify the genes involved in the ability of k. pneumoniae to form a biofilm on abiotic surfaces, a novel strategy was used. a clone library was constructed by cloning the entire k. pneumoniae genome of the clinical isolate c3091 into a fosmid vector and the clone libra ... | 2010 | 20482632 |
| in vitro susceptibility to various antibiotics of colistin-resistant gram-negative bacterial isolates in a general tertiary hospital in crete, greece. | 2010 | 20482269 | |
| klebsiella pneumoniae bacteraemia complicating rotavirus gastroenteritis in two infants with glucocorticoid deficiency. | rotavirus gastroenteritis was complicated by klebsiella pneumoniae bacteraemia in two infants with glucocorticoid deficient conditions who were treated with 'stress dose' hydrocortisone during their illness. delayed healing in the context of glucocorticoid administration combined with damage from rotavirus infection may result in increased risk of mucosal invasion by gastrointestinal bacteria and subsequent enteric gram-negative bacteraemia. | 2010 | 20480730 |
| bacteriological quality of drinking water in nyala, south darfur, sudan. | the objective of this study was to determine the bacterial contaminations in drinking water in nyala city, south darfur, sudan with special reference to the internally displaced people camps (idps). two hundred and forty water samples from different sites and sources including bore holes, hand pumps, dug wells, water points, water reservoir and household storage containers were collected in 2009. the most probable number method was used to detect and count the total coliform, faecal coliform and ... | 2011 | 20480392 |
| identification of helicobacter pylori in gallstone, bile, and other hepatobiliary tissues of patients with cholecystitis. | bacterial infection is accepted as a precipitating factor in cholesterol gallstone formation, and recent studies have revealed the presence of helicobacter species in the hepatobiliary system. we utilized the polymerase chain reaction (pcr) to establish the presence of bacterial dna, including from helicobacter species, in gallstones, bile juice, and gallbladder mucosa from patients with gallstones. | 2010 | 20479914 |
| a novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane. | polymyxins are cationic lipopeptides (five cationic charges) and the last resort for the treatment of serious gram-negative infections caused by multiresistant strains. nab741 has a cyclic peptide portion identical to that of polymyxin b but carries in the linear peptide portion a threonyl-d-serinyl residue (no cationic charges) instead of the diaminobutyryl-threonyl-diaminobutyryl residue (two cationic charges). at the n terminus of the peptide, nab741 carries an acetyl group instead of a mixtu ... | 2010 | 20479195 |
| activity of chequerboard combinations of ceftaroline and nxl104 versus beta-lactamase-producing enterobacteriaceae. | ceftaroline is a novel oxyimino-cephalosporin, strongly active against methicillin-resistant staphylococci and pneumococci. it is active against enterobacteriaceae too, but is labile to common beta-lactamases, including ampc and extended-spectrum types. to counteract these enzymes, ceftaroline is also being developed combined with nxl104, a beta-lactamase inhibitor. | 2010 | 20478991 |
| biofilms on tracheoesophageal voice prostheses: a confocal laser scanning microscopy demonstration of mixed bacterial and yeast biofilms. | the aim of this study was to demonstrate the presence of yeast and bacterial biofilms on the surface of tracheoesophageal voice prostheses (tvps) by a double-staining technique with confocal laser scanning microscopy (clsm). biofilms of 12 removed tvps were visualized by scanning electron microscopy, then stained with cona-fitc and propidium iodide for clsm. microbial identification was by partial 16s rrna gene analysis and its-2 sequence analysis. microbial biofilms on the tvps consisted of bac ... | 2010 | 20473799 |
| production and characterization of a group of bioemulsifiers from the marine bacillus velezensis strain h3. | marine microbes are a rich source of bioactive compounds, such as drugs, enzymes, and biosurfactants. to explore the bioactive compounds from our marine natural product library, an oil emulsification assay was applied to discover biosurfactants and bioemulsifiers. a spore-forming bacterial strain from sea mud was found to produce bioemulsifiers with good biosurfactant activity and a broad spectrum of antimicrobial properties. it was identified as bacillus velezensis h3 using genomic and phenotyp ... | 2010 | 20473663 |
| antibiotic resistance in orthopaedic surgery: acute knee prosthetic joint infections due to extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae. | the aim of this study was to describe the prevalence and characteristics of knee prosthetic joint infections due to extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae. from 2000 to 2007, 132 infections out of 5,076 arthroplasties (2.6%) were registered. seven out of 132 infections (5.3%) were due to esbl-producing enterobacteriaceae, escherichia coli in six cases and klebsiella pneumoniae in one. open debridement and retention of the implant was the first surgical approach and ... | 2010 | 20473541 |
| the filter-feeding ciliates colpidium striatum and tetrahymena pyriformis display selective feeding behaviours in the presence of mixed, equally-sized, bacterial prey. | this study examined whether two ciliates could discriminate between equally-sized bacterial prey in mixture and if so, how selectivity might benefit the ciliate population. live klebsiella aerogenes, k. ozaenae and escherichia coli, expressing different coloured fluorescent proteins, were cultured in such a way as to provide populations containing equally-sized cells (to prevent size-selective grazing taking place) and these prey were fed to each ciliate in 50:50 mixtures. colpidium striatum sel ... | 2010 | 20471910 |
| cefepime-resistant gram-negative bacteremia in febrile neutropenic patients with hematological malignancies. | this study was performed to determine the local etiologic pattern of blood culture isolates and antibiotic resistance in febrile neutropenic patients with hematological malignancies. | 2010 | 20471883 |
| bloodstream infections caused by esbl-producing e. coli and k. pneumoniae: risk factors for multidrug-resistance. | this prospective case-control study was conducted from october 2003 to june 2007 to evaluate risk factors for multidrug resistance among extended-spectrum-b-lactamase-producing escherichia coli and klebsiella spp. (esbl-ek) isolates in blood cultures. all adult patients (>18 years old) whose blood cultures grew esbl-ek during the study period were included. an esbl-ek isolate was defined as mdr if it was resistant to at least one member of following two classes of antibiotics: aminoglycosides (a ... | 2009 | 20464329 |
| in vivo acquisition of a plasmid-mediated bla(kpc-2) gene among clonal isolates of serratia marcescens. | three patients admitted to a greek hospital were infected with serratia marcescens isolates that exhibited reduced susceptibility to carbapenems and harbored klebsiella pneumoniae carbapenemase (kpc) enzymes. in two of these cases, the patients were initially infected by carbapenem-susceptible s. marcescens isolates. molecular typing and plasmid analysis suggested that all three patients had clonally indistinguishable isolates of s. marcescens that acquired a plasmid-mediated bla(kpc-2) gene dur ... | 2010 | 20463153 |
| high prevalence of extended-spectrum beta-lactamases and plasmid-mediated ampc beta-lactamases in enterobacteriaceae isolated from long-term care facilities in korea. | the aim of this study was to investigate for the first time the prevalence and types of extended-spectrum beta-lactamase (esbl) and plasmid-mediated ampc beta-lactamase (pabl) in enterobacteriaceae in korean long-term care facilities (ltcfs). esbl rates were 45.3% (72/159) in escherichia coli and 42.7% (50/117) in klebsiella pneumoniae. in e. coli, ctx-m-28, the most prevalent esbls, was identified for the first time in korea in 44 isolates. in k. pneumoniae, shv-12 was found in 27 isolates (52. ... | 2010 | 20462727 |
| outbreak of klebsiella pneumoniae producing kpc-2 and shv-12 in a french hospital. | 2010 | 20460399 | |
| effects of the usa patriot act and the 2002 bioterrorism preparedness act on select agent research in the united states. | a bibliometric analysis of the bacillus anthracis and ebola virus archival literature was conducted to determine whether negative consequences of the uniting and strengthening america by providing appropriate tools required to intercept and obstruct terrorism" (usa patriot) act and the 2002 bioterrorism preparedness act on us select agent research could be discerned. indicators of the health of the field, such as number of papers published per year, number of researchers authoring papers, and in ... | 2010 | 20457912 |
| emergence of resistant klebsiella pneumoniae in the intestinal tract during successful treatment of klebsiella pneumoniae lung infection in rats. | antibiotic treatment of lung infections may lead to the emergence of resistance in the gut flora. appropriate dosing regimens could mitigate this adverse effect. in gnotobiotic rats harboring intestinal escherichia coli and enterococcus faecium populations, a lung infection by klebsiella pneumoniae was instigated with two different sizes of inoculum to represent an early or a late initiation of antibiotic treatment. the rats were treated with marbofloxacin, an expanded-spectrum fluoroquinolone, ... | 2010 | 20457820 |
| intervention study of the association of antibiotic utilization measures with control of extended-spectrum beta-lactamase (esbl)-producing bacteria. | we investigated the effects of replacing third-/fourth-generation cephalosporins with piperacillin-tazobactam on the rate of acquisition of extended spectrum beta-lactamase-producing klebsiella pneumoniae and escherichia coli by patients hospitalized in a department of respiratory medicine. this 9-month, prospective, non-controlled, intervention study comprised two phases: a 3-month pre-intervention phase (phase i) and a 6-month intervention phase (phase ii), during which the use of third-/forth ... | 2010 | 20457272 |
| a simple and effective approach for the treatment of diabetic foot ulcers with different wagner grades. | diabetic foot infections are the major cause of morbidity. infection is the common sequel of diabetic foot ulceration that leads to delayed wound healing. these infections are difficult to control. if not addressed well in time, they may lead to amputation of foot. an attempt has been made to develop simple and effective treatment modality by using citric acid as a sole antimicrobial agent to control diabetic foot infections not responding to conventional treatment. hundred and fifteen cases of ... | 2010 | 20455958 |
| [investigation of the in vitro antibacterial effects of statins]. | it was previously shown that statins have anti-inflammatory, immunomodulatory and anti-oxidant effects. this study was aimed to investigate the in-vitro antibacterial effects of simvastatin and atorvastatin. in this study antibacterial activity of the statins were tested against 16 methicillin-susceptible stophylococcus aureus (mssa), 16 methicillin-resistant s.aureus (mrsa), 16 methicillin-resistant coagulase-negative staphylococcus (mrcons), 9 vancomycin-susceptible enterococcus faecium, 7 van ... | 2010 | 20455414 |
| [the performance of two different chromogenic media for the diagnosis of extended spectrum beta-lactamase producing strains]. | the aim of this study was to evaluate the performances of 2 different chromogenic media for the detection of extended spectrum beta-lactamase (esbl) producing escherichia coli and klebsiella spp. isolated from different clinical samples of patients who were admitted to baskent university faculty of medicine, adana application and research hospital between september to november 2007. a total of 365 strains [251 were esbl positive and 114 were negative by double disc synergy (dds) test] of which 2 ... | 2010 | 20455405 |
| [molecular epidemiology of carbapenem-resistant klebsiella pneumoniae strains isolated between 2004-2007 in ankara university hospital, turkey]. | the prevalence of carbapenem-resistant gram-negative bacteria in the hospital setting is in an increasing trend worldwide. since most of the carbapenem-resistant enterobacteriaceae are resistant to all antimicrobial agents except polymyxins and tigecycline, the emergence of carbapenem resistance in klebsiella pneumoniae strains requires careful monitoring. this study was conducted to analyse the epidemiological relatedness between the carbapenem-resistant isolates of k. pneumoniae collected from ... | 2010 | 20455393 |
| antimicrobial activity and a sar study of some novel benzimidazole derivatives bearing hydrazone moiety. | in this study 12 novel benzimidazole compounds bearing hydrazone moiety were synthesized in order to investigate their possible antibacterial and antifungal activity. structures of the synthesized compounds were elucidated by spectral data. six different gram-negative and four different gram-positive bacterial strains were used in antibacterial activity tests. antifungal activity tests were also performed against three different fungal strains. most of the test compounds found to be significantl ... | 2010 | 20451306 |
| qualitative phytochemical screening and in vitro antimicrobial effects of methanol stem bark extract of ficus thonningii (moraceae). | the methanolic stem bark extract of ficus thonningii (moraceae) was subjected to preliminary phytochemical screening and in vitro antimicrobial tests. the phytochemical tests was carried out using standard methods of analysis and these investigations revealed the presence of alkaloids, anthraquinones, carbohydrates, flavonoids, saponins and tannins. the antimicrobial activity of the plant extract was assayed using the agar plate disc diffusion and nutrient broth dilution techniques. test micro o ... | 2009 | 20448855 |
| screening of antibacterial potentials of some medicinal plants from melghat forest in india. | cyperus rotundus, caesalpinia bonducella, tinospora cordifolia, gardenia gummifera, ailanthus excelsa, acacia arabica, embelia ribes and ventilago maderspatana from melghat forest were screened for their antibacterial potential against escherichia coli, staphylococcus aureus, klebsiella pneumoniae, proteus vulgaris, salmonella typhi, shigella flexneri, salmonella paratyphi, salmonella typhimurium, pseudomonas aeruginosa, enterobacter aerogenes by disc diffusion method. out of these medicinal pla ... | 2009 | 20448847 |
| primary klebsiella pneumoniae liver abscess with metastatic spread to lung and eye, a north-european case report of an emerging syndrome. | a syndrome of community acquired liver abscess caused by highly virulent hypermucoviscous, rmpa positive klebsiella pneumoniae strains occurs with high incidence in asia. we here report a case complicated by metastatic infection, to our knowledge, the first one described in northern europe. this and other recently reported cases indicate the emergence of this severe syndrome outside of asia. | 2010 | 20448814 |
| effects of plant growth promoting bacteria and mycorrhizal on capsicum annuum l. var. aviculare ([dierbach] d'arcy and eshbaugh) germination under stressing abiotic conditions. | capsicum annuum var. aviculare to tarahumara and papago indians and farmers of sonora desert is a promising biological and commercial value as a natural resource from arid and semiarid coastal zones. traditionally, apply synthetic fertilizers to compensate for soil nitrogen deficiency. however, indiscriminate use of these fertilizers might increase salinity. the inoculation by plant growth promoting bacteria (pgpb) and arbuscular mycorrhizal fungi (amf) represents an alternative as potential bio ... | 2010 | 20447830 |
| the profile of antibiotics resistance and integrons of extended-spectrum beta-lactamase producing thermotolerant coliforms isolated from the yangtze river basin in chongqing. | the spreading of extended-spectrum beta-lactamases (esbl)-producing thermotolerant coliforms (tc) in the water environment is a threat to human health but little is known about esbl-producing tcs in the yangtze river. we received 319 esbl-producing stains obtained from the chongqing basin and we investigated antibiotic susceptibility, bla gene types and the presence of integrons and gene cassettes. 16.8% of tc isolates were esbl-producing bacteria and bla(tem+ctx-m) was the predominant esbl type ... | 2010 | 20447743 |
| klebsiella pneumoniae carbapenemase-producing enterobacteriaceae. | carbapenem-resistant enterobacteriaceae, particularly klebsiella pneumoniae, are rapidly emerging as significant health care-associated pathogens. because of the adverse impact that infection caused by these extensively drug-resistant organisms can have on patient outcomes, efforts to prevent further transmission of these pathogens within the health care setting are urgently needed. in this article, the epidemiology, detection, and prevention of carbapenem-resistant enterobacteriaceae are descri ... | 2010 | 20442598 |
| ventilator-associated pneumonia in a tertiary care hospital in india: role of multi-drug resistant pathogens. | ventilator-associated pneumonia (vap) is the most frequent intensive-care-unit (icu)-acquired infection. the aetiology of vap varies with different patient populations and types of icus. | 2010 | 20440059 |
| antimicrobial susceptibility patterns of community-acquired uropathogens in tehran, iran. | antibiotic resistance of urinary tract pathogens has increased worldwide. knowledge of the antibiotic resistance patterns of uropathogens in specific geographical locations is an important factor for choosing an appropriate empirical antimicrobial treatment. the aim of this study was to provide information regarding local resistance patterns of urinary pathogens to the commonly used antibiotics in tehran, iran. | 2010 | 20440056 |