Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [left ventricular pressure-volume diagram determined by forward and backward formatting of radionuclide ventriculography and analog pressure data]. | pressure-volume (pv) loop is of great value for the assessment of left ventricular (lv) function, but its clinical application has been limited by methodological complexity. a new system was developed to make accurate loop with simplified procedure, and was applied to clinical and interventional study. the system constitutes of a mobile gamma camera, a poly-amplifier and a data processor (gms-550u, toshiba medical) installed in cardiac catheterization labo for simultaneous raw data handling and ... | 2009 | 2786583 |
| [outline of proliferative disorders in the mononuclear phagocytic system--clinicopathological aspects of histiocytosis x]. | 2009 | 2786580 | |
| cholinergic contraction to field stimulation in coronary arteries of cattle. | epicardial coronary artery strips of cattle hearts mounted in vitro respond to transmural stimulation with a neurogenic constriction, attributable to the endogenous release of acetylcholine. these responses were elicited with frequencies as low as 1.0 hz and with pulse durations as low as 100 microseconds. the magnitude of the contractile response increased with increasing frequency of stimulation. blockade of adrenergic neuronal mechanisms with guanethidine (5 x 10(-6) m) increased the size of ... | 1989 | 2786563 |
| reliability and validity of expected outcomes and barriers for habitual physical activity. | we conducted two studies to examine the reliability and validity of self-report scales for assessing outcome-expectancy values and perceived barriers for participating in regular physical activity. in study one with college students (n = 243), independent and reliable psychometric factors were identified as outcome-expectancy values (psychologic, body image, and health) and perceived barriers (time, effort, and obstacles). alpha internal consistency coefficients ranged from .47 to .78, and test- ... | 2009 | 2786559 |
| enhanced antitumor effect of combination therapy with interleukin-2 and polyribonucleotides against adenocarcinoma 755. | human recombinant interleukin-2 (il-2) and interferon (ifn) inducers in combination were evaluated for their in vivo antitumor efficacy in relation to s.c.-implanted adenocarcinoma 755 in c57bl/6 mice. two ifn inducers, polyinosinic-polycytidylic acid [poly(i)poly(c)] and polyadenylic-polyuridylic acid [poly(a)poly(u)], induced high ifn production in various tissues for a long time compared to treatment with murine interferon-beta. especially, poly(i)poly(c) at 5 mg/kg, the maximum tolerated dos ... | 1989 | 2786554 |
| [the results of an investigation of the various factors influencing the late patency ratio of coronary bypass grafting]. | the purpose of this communication was to find out the factors influencing the late patency ratio of coronary artery bypass grafts of 42 patients in our institution. the following results were obtained: 1. the size of the measured diameters of coronary arteries and the graft flow rates were correlated well to the late patency ratio (p less than 0.05). 2. the regular physical exercise trainings were significantly important to keep patent grafts (p less than 0.01). 3. in blood serum studies, serum ... | 2009 | 2786538 |
| sv40 t antigen acts as a minor histocompatibility antigen of sv40 t antigen tolerant transgenic mice. | the ability of normal mice to mount an sv40 t antigen-specific cytolytic t lymphocytes response when immunized in vivo with splenocytes from the sv40 t antigen transgenic 427-line mice and restimulated in vitro with sv40-transformed fibroblasts, or when immunized with sv40 and restimulated with 427-line splenocytes, was analyzed. both immunization schemes resulted in an sv40 t antigen-specific immune response, indicating the presence of sv40 t antigen-positive cells in the spleens of these trans ... | 1989 | 2786497 |
| human t lymphocytes possess a limited in vitro life span. | the t lymphocyte offers certain theoretical advantages over other available cell types for the study of aging. immunosenescence is a well-established part of, and may be directly relevant to, mammalian aging, and the t lymphocyte is well-characterized as to function, cell-surface antigen make-up, and other factors. however, prior efforts at studying in vitro aging of t cells have been hampered by poor reproducibility in doubling potential and the occurrence of a peculiar type of crisis. we have ... | 1989 | 2786475 |
| co-localization of corticotropin-releasing factor- and enkephalin-like immunoreactivities in nerve cells of the rat hypothalamus and adjacent areas. | the co-localization of corticotropin-releasing factor (crf)- and enkephalin (enk)-like immunoreactivities in nerve cells of the rat hypothalamus and adjacent areas was investigated by the simultaneous application of immuno-beta-galactosidase staining and the peroxidase-antiperoxidase (pap) method to the same sections. crf-like immunoreactive cells were stained blue with immuno-beta-galactosidase staining and enk-like immunoreactive cells brown with the pap method. double-labeled cells with overl ... | 1989 | 2786446 |
| [clinico-immunological changes in patients with chronic pancreatitis and their correction during the treatment]. | the time course of quantitative and functional parameters of humoral and cellular immunity, autosensitization to pancreatic tissue was studied in 200 patients with chronic pancreatitis. it was shown that different clinical types of the disease were characterized by different types of immune shifts. correlation was found between clinical and immunological indices. immunosuppressive influence of protease inhibitors in chronic pancreatitis was shown. incorporation of the immunomodulator levamisole ... | 2009 | 2786262 |
| two cases of pneumocystis carinii pneumonia occurred in human immunodeficiency virus infected patients: supplemental treatment with aerosolised pentamidine isethionate. | two cases of pneumocystis carinii pneumonia occurred in human immunodeficiency virus infected patients who were diagnosed by the aspiration-lung-biopsy. they were treated with 4 mg/kg of pentamidine isethionate intravenously administered followed by pentamidine aerosol inhalation. although clinical and laboratory findings were improved by the fifth or seventh day of intravenous therapy, substantial leukocytopenia, from 3,000/cmm to 600/cmm and from 2,700/cmm to 1,000/cmm, occurred. at this point ... | 1989 | 2786100 |
| [aids. pneumocystis pneumonia: prevention is in sight]. | 2009 | 2785477 | |
| prevalence of tmj symptoms and x-ray findings. | some results of the fifteen year longitudinal groningen study on tmj dysfunction are reported. the prevalence of subjectively communicated symptoms appears to consistently increase with age. the recording of 21 percent pain at the last check-up was judged high. objectively determined symptom frequencies (in the literature sometimes indicated signs) seem to level off in the early twenties. observed x-ray deformities or flattening of the condyle did not increase substantially. the symptoms registe ... | 2009 | 2785455 |
| trophic effects of first-trimester human trophoblasts and human chorionic gonadotropin on lymphocyte proliferation. | we examined the effects of pure first-trimester human trophoblast cells grown in long-term cultures or their secreted products on the proliferation of human peripheral blood lymphocytes cultured alone, under allogeneic stimulation, or in the presence of concanavalin a. both trophoblasts and their culture supernatants stimulated lymphocyte proliferation. culture supernatant had a moderate enhancing effect on lymphocyte mitogenesis in mixed lymphocyte cultures and in the presence of concanavalin a ... | 1989 | 2785344 |
| the importance of splenectomy for the adoptive immunotherapy of cancer. | adoptive immunotherapy (ait) of cancer using lymphocytes cultured in vitro in interleukin-2 (lak cells) has gained much attention due to the high level of broad anti-tumor activity both in vitro and in vivo. a major hypothesis has suggested that if unfractionated lymphoid cells grown in il-2 can mediate significant anti-tumor effects then purified lak effector cells should yield even higher activity. furthermore, devising new techniques to achieve optimal expansion of the purified lak effector c ... | 2009 | 2785238 |
| a fluorescence-based assay for quantitation of lymphokine-activated killer cell activity. | a fluorescence assay for the quantitation of tumor cell lysis by activated and non-activated killer (lak) cells is described. the target cells are labelled with a europium chelate (eu-diethylenetriaminopentaacetate) and after cytolysis caused by the lak cells the eu3+ complex is released into the culture supernatant. the addition of beta-naphthoyltrifluoroacetone to culture supernatant aliquots leads to the formation of a highly fluorescent chelate which can be measured with a time-resolved fluo ... | 2009 | 2785144 |
| production of human cells expressing individual transferred hla-a,-b,-c genes using an hla-a,-b,-c null human cell line. | we detail in this report the characterization of a human b-lymphoblastoid cell line, .221, that does not express endogenous hla-a, hla-b, or hla-c class i ag due to gamma-ray-induced mutations in the hla complex. mutant .221 is characterized by: 1) complete absence of hla-a,-b,-c mrna transcripts and alpha-chains, and 2) intracellular expression of two non-a,-b,-c class i alpha-chains with an abundance less than or equal to 1% of normal hla-a,-b,-c expression on similar cells. however, transferr ... | 1989 | 2785140 |
| tumor necrosis factor-alpha activation of the il-2 receptor-alpha gene involves the induction of kappa b-specific dna binding proteins. | tnf-alpha induces the expression of il-2r and promotes the proliferation and differentiation of t and b cells. in this report, we have studied the biochemical basis for tnf-alpha activation of the il-2r alpha (tac, p55) gene. transfection of human t cell lines with selectively mutated forms of the il-2r alpha promoter revealed that a kappa b element (nucleotides -267 to -256), as well as 5' flanking sequences (nucleotides -281 to -271) are required for tnf-alpha induction of this transcriptional ... | 1989 | 2785134 |
| post-irradiation regeneration of early b-lymphocyte precursor cells in mouse bone marrow. | to examine the sequential development of early b-cell precursors in mouse bone marrow, b-lineage cells have been examined during a wave of post-irradiation regeneration. cell phenotypes have been defined using double-immunofluorescence labelling techniques for (i) terminal deoxynucleotidyl transferase (tdt); (ii) b220 glycoprotein, detected by the binding of mab 14.8; (iii); mu heavy chains in the cytoplasm (c mu) and at the cell surface (s mu). three populations of mu- cells (tdt+14.8-; tdt+14. ... | 1989 | 2784779 |
| characteristics of human synovial fibroblast activation by il-1 beta and tnf alpha. | human synovial fibroblast cell lines (hsn), established from tissues obtained from the knee joints of arthritis patients undergoing arthoplasty, were used to investigate the effects of human interleukin-1 (il-1) beta and tumour necrosis factor (tnf)alpha on proliferation and prostaglandin e2 (pge2) secretion. il-1 beta and tnf alpha were equipotent stimulators of hsn proliferation. classical non-steroidal anti-inflammatory drugs and glucocorticoids significantly augmented this effect. in additio ... | 1989 | 2784408 |
| introduction of a ha-ras oncogene into rat liver epithelial cells and parenchymal hepatocytes confers resistance to the growth inhibitory effects of tgf-beta. | growth of rat liver epithelial cells (rlec) and primary cultures of parenchymal hepatocytes is potently inhibited by tgf-beta. transfection of a mutated ha-ras oncogene, but not a human c-myc oncogene, into rlec resulted in cell lines resistant to growth inhibition by tgf-beta under anchorage-dependent conditions. infection of primary rat hepatocyte cultures with v-ha-ras yielded a cell line likewise insensitive to inhibition by tgf-beta. binding of [125i]tgf-beta to ha-ras-transfected rlec was ... | 1989 | 2783773 |
| diagnostic and therapeutic technology assessment (datta). noninvasive electrical stimulation for nonunited bone fracture. | 2009 | 2783614 | |
| neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type a. | moclobemide belongs to a new generation of short-acting, reversible, monoamine oxidase (mao) inhibitors. in vitro (rat brain homogenates) moclobemide inhibits mao-a selectively with lower potency than many of the reference mao inhibitors. however, when measured ex vivo in the rat, the potency of moclobemide is similar to that of reference compounds. in vivo the drug induces a dose-dependent, short-lasting (8-16 hr) and preferential inhibition of mao-a in the brain and both mao-a and mao-b inhibi ... | 1989 | 2783611 |
| neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type a. | moclobemide belongs to a new generation of short-acting, reversible, monoamine oxidase (mao) inhibitors. in vitro (rat brain homogenates) moclobemide inhibits mao-a selectively with lower potency than many of the reference mao inhibitors. however, when measured ex vivo in the rat, the potency of moclobemide is similar to that of reference compounds. in vivo the drug induces a dose-dependent, short-lasting (8-16 hr) and preferential inhibition of mao-a in the brain and both mao-a and mao-b inhibi ... | 1989 | 2783611 |
| bone marrow progenitor cells induce a regulatory autologous proliferative t lymphocyte response. | the proliferative response of human t lymphocytes to autologous bone marrow progenitor cells was studied by in vitro coculture in autologous serum. irradiated enriched bone marrow progenitor cells induced the proliferation of cocultured peripheral blood t cells, with maximal proliferation at 8 days and stimulator:proliferator ratios of 1/1. this autologous proliferative t lymphocyte response was completely abrogated by the inclusion of anti-hla-dr, anti-cd2, or anti lfa-3 antibodies into the coc ... | 1989 | 2783600 |
| interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to pdgf-aa. | both interleukin-1 (il-1) and platelet-derived growth factor (pdgf) induce proliferation of cultured fibroblasts and smooth muscle cells. these polypeptide mediators are released by activated macrophages and other cell types in response to injury and are thought to have a role in tissue remodeling and a number of pathologic processes. analysis of the kinetics of [3h]thymidine incorporation by cultured fibroblasts demonstrated that the response to il-1 is delayed approximately 8 hours relative to ... | 2009 | 2783498 |
| imaging of brain tumors with l-3-[123i]iodo-alpha-methyl tyrosine and spect. | carbon-11-labeled amino acids have been successfully used to image brain tumors by pet. this study was undertaken to evaluate the potential of l-3-[123i]-iodo-alpha-methyl tyrosine (123imt) for metabolic imaging of brain tumors. ten patients (glioblastoma, oligodendroglioma, lymphoma, and metastases) had early and delayed brain spect with a rotating gamma camera after i.v.-injection of 200-300 mbq 123imt. in nine patients the tumors showed intense uptake of the radiotracer. tumor-to-brain tissue ... | 2009 | 2783455 |
| human eosinophils express cd4 protein and bind human immunodeficiency virus 1 gp120. | the cd4 glycoprotein, expressed on leukocytes belonging to subsets of t lymphocytes and to cells of monocyte/macrophage lineage, participates in the functioning of t cells and serves as a receptor for hiv-1 and hiv-2. human eosinophils, a class of granulocytic leukocytes, have been found to express cd4. with anti-cd4 mabs cd4 was demonstrable on eosinophils from both normal and eosinophilic donors. eosinophils synthesized a 55-kd cd4 polypeptide immunoprecipitable with two anti-cd4 mabs. eosinop ... | 1989 | 2783333 |
| segmental latissimus dorsi free flap: clinical applications. | for 15 years, the latissimus dorsi muscle has enjoyed a consistent reputation with reconstructive surgeons as a reliable pedicle or free flap transferred with or without a skin island. previous laboratory investigation has delineated the neurovascular intramuscular anatomy. the segmental latissimus transfer makes use of the intramuscular anatomy such that a lateral segment of the muscle is denervated and transferred with the thoracodorsal vascular pedicle while the medial segment of the muscle r ... | 2009 | 2782823 |
| quantitative assessment of the biological effects of follicle regulatory protein on dihydrotestosterone-maintained spermatogenesis in hypophysectomized rat. | follicle regulatory protein (frp) isolated from porcine ovarian follicles influences folliculogenesis through a paracrine mechanism. a similar protein has been found in the testes and seems to have some inhibitory effects on spermatogenesis when administered to intact male experimental animals. on the basis of female and male studies, it has been ascertained that the effects of frp are at the level of gonads and not the pituitary or the hypothalamus. in the studies with intact males it was not p ... | 1989 | 2782630 |
| [comparative evaluation of the levels of water-soluble glial fibrillary acidic protein in the human brain in the normal state and in schizophrenia]. | the concentration of water-soluble glial fibrillary acidic protein was measured in several regions of human brains (12 schizophrenic patients and 13 patients without any signs of mental disease) using elisa technique. the content of this protein was lower in thalamus and gyrus cinguli in schizophrenics as compared to normals (p less than 0.01). the protein showed no correlation with sex, age and the terms of autopsy (5 to 7 h after death). the findings suggest that decreasing concentration of th ... | 1989 | 2781906 |
| growth of staphylococcus aureus and synthesis of enterotoxins in home-made yoghurt. | staphylococcus aureus strains fri-100, s6, fri-137 and fri 472 were inoculated into milk to study growth and enterotoxin production in home-made yogurts. the yogurt used as starter was progressively weakened by successive inoculations (up to four) in milk to prepare other yogurts in order to study the ability of yogurt microflora to inhibit staphylococci. after elaboration, yogurts were stored at 4 degrees c, 22 degrees c, and 37 degrees c for a maximum of 21 days. periodically, staphylococcal c ... | 1989 | 2781867 |
| skin test responsiveness to a series of new tuberculins of children living in three vietnamese cities. | a skin test survey was conducted among 1035 children aged 7-19 years living in three cities in vietnam. fifteen new tuberculins, including leprosin-a, were applied; an induration of 2 mm diameter or more was considered positive. compared to some other tropical countries, low levels of sensitisation were recorded and remarkable regional differences were found. positivity to any tuberculins (pooled data) among non-bcg-vaccinated children was significantly lower in hanoi (13.1%) and hochiminh-city ... | 1989 | 2781608 |
| cross-reactive binding patterns of monoclonal antibodies to dna are often caused by dna/anti-dna immune complexes. | recently, the role of antibodies to dna in the pathogenesis of systemic lupus erythematosus (sle) has been reevaluated, since observed cross-reactive binding of anti-dna to tissue-related antigens might substantially contribute to the inflammatory process of the disease. evidence of this cross-reactivity has, in part, been obtained from studies with monoclonal anti-dna. however, we now report that the presence of dna/anti-dna immune complexes in monoclonal antibody preparations may be the cause ... | 2009 | 2781137 |
| opening remarks of president fernando e. agrait on the occasion of the 50th anniversary of the cayo santiago macaque colony. | 1989 | 2780954 | |
| reasons for the ineffectiveness of eglin c to ameliorate endotoxin shock in sheep. | 1989 | 2780742 | |
| rat gene 33: analysis of its structure, messenger rna and basal promoter activity. | several overlapping cdna and genomic dna clones corresponding to mrna g33 and gene 33, respectively, were isolated and characterized. the mrna g33 molecule is 2971 nt in length, exclusive of a poly(a+) tail, and encodes a putative 459 amino acid protein (49,946 daltons). the 13.2 kbp gene consists of four exons, three introns, and has two initiation sites located 27 and 30 bp downstream from a tata box. transfection of h4iie cells with a fusion gene 33 (-1900 to +32)/luciferase construct (psl330 ... | 1989 | 2780291 |
| [injuries of the lumbosacral segments of the spine]. | having studied 470 case histories of patients with injuries of the spine the author found traumas of the 5th lumbar vertebra in 23 cases (4.9%). the characteristic injuries were compression wedge-shaped fractures, multiple fractures of the vertebrae, comminuted and traumatic spondylolistheses and dislocation fractures. a typical mechanism of the injury was a blow in the lumbar region or in the back with subsequent bending of the trunk. the tactics of surgical treatment of such lesions is present ... | 2007 | 2780029 |
| evolution of androgen-regulated ornithine decarboxylase expression in mouse kidney. | the analysis of naturally occurring variations in hormone-regulated gene expression generates insights into the mechanisms governing evolutionary changes in hormone response. in the mouse (genus mus), kidney ornithine decarboxylase (odc) expression, which is regulated by androgens, has been modified during evolution. this has resulted in intra- and interspecies variations that have accumulated over a 10-15 million year time period. we have examined odc expression and its response to androgens in ... | 1989 | 2779581 |
| purification of cross-reacting protein antigen shared by yersinia enterocolitica and other gram-negative bacteria with monoclonal antibody. | a monoclonal antibody against the yersinia enterocolitica 60-kilodalton (kda) antigen, designated cross-reacting protein antigen (crpa), was obtained by cell fusion. the crpa common to gram-negative bacteria was purified from y. enterocolitica by the affinity chromatography with the monoclonal antibody (igg1) thus obtained. the purified crpa showed a single band of 60 kda in sds-polyacrylamide gel electrophoresis (sds-page), and reacted with rabbit antisera against y. enterocolitica, vibrio chol ... | 1989 | 2779474 |
| sugar composition of the polysaccharide portion of lipopolysaccharides isolated from non-o1 vibrio cholerae o2 to o41, o44, and o68. | the sugar composition of the polysaccharide portion of lipopolysaccharides (lps) was determined for 42 serovars of non-o1 vibrio cholerae, i.e., from serogroups o2 to o41, o44, and o68. on the basis of their compositional sugar pattern, they were classified into 24 chemotypes. 2-keto-3-deoxyoctonate (kdo) was totally undetectable by the conventional color test (weissbach's reaction) under the conventional hydrolysis conditions. instead, a kind of kdo-like substance, which was positive in the rea ... | 1989 | 2779472 |
| hemolytic vibrio cholerae o1 that is sensitive to mukerjee's cholera phage iv and the phage produced by the hemolytic vibrio lysogenized with the infection of mukerjee's cholera phage iv. | strains of hemolytic vibrio cholerae o1 (el tor vibrio) which are sensitive to mukerjee's cholera phage group iv were isolated from cholera patients in north-east thailand in 1986. plaques of the phage on these hemolytic v. cholerae o1 were usually translucent but almost transparent on some strains, just like the plaques on non-hemolytic v. cholerae o1 (classical vibrio). these hemolytic v. cholerae o1 were lysogenized with the infection of cholera phage iv, and the lysogenized strains produced ... | 1989 | 2779469 |
| [total anomalous pulmonary venous connection in adult: report of a case]. | total anomalous pulmonary venous connection (tapvc) is a cardiac disorder that seldom permits survival into adulthood without surgical correction in infancy. we reported a successful total correction in a 47-year-old man with tapvc. cardiovascular angiography demonstrated the features of darling i a type tapvc. cardiac catheterization showed qp/qs: 5.8, pp/ps: 0.31, rp/rs: 0.06 and mild pulmonary hypertension. on operation, the posterior wall of left atrium anastomosed to the common pulmonary ve ... | 1989 | 2779053 |
| interpreting the carboxyhaemoglobin concentration in fetal cord blood. | we calculated the fetal-to-maternal carboxyhaemoglobin concentration ratio in 19 mother-infant pairs at the time of term delivery. mothers, who had a less than 10% drop in their carboxyhaemoglobin concentration during labour, had an average ratio of 1.40 +/- 0.19. for mothers whose carboxyhaemoglobin concentrations dropped by 10% or more during labour, the average fetal-to-maternal carboxyhaemoglobin concentration ratio was 1.83 +/- 0.48. there was a strong correlation (r = 0.82) between the per ... | 2009 | 2778293 |
| day care in teaching hospitals. | 2009 | 2778250 | |
| anomalous origin of right pulmonary artery from the ascending aorta. | anomalous origin of one pulmonary artery from the ascending aorta without associated intracardiac defects is a rare congenital malformation. about 60 anatomic and surgical descriptions have been reported in the literature. up to 1974, 22 of the 50 reported cases underwent surgical correction with a 40% mortality rate. the natural history without surgery is poor with a very high mortality during the first year of life. successful anatomic correction of anomalous origin of right pulmonary artery f ... | 2009 | 2777879 |
| an actin-depolymerizing protein in embryonic chicken skeletal muscle: purification and characterization. | in embryonic skeletal muscle, a large amount of non-polymerized actin exists in the cytoplasm (shimizu and obinata [1986] j. biochem. 99, 751-759). a 19-kda protein (called 19k protein) which binds to g-actin was purified by sequential chromatography on dnase i-agarose, hydroxylapatite, sp-sephadex, and sephadex g-75, from the sarcoplasmic fraction of embryonic chicken skeletal muscle. this protein decreased the extent of actin polymerization at a steady state and increased the monomeric actin i ... | 1989 | 2777748 |
| pharmacokinetics and tissue penetration of cefepime. | the pharmacokinetics of cefepime were studied following a 2 g intravenous infusion, by measuring concentrations in plasma, inflammatory fluid and urine. mean peak plasma concentrations of 193.1 mg/l were achieved at the end of the 30 min infusion. the mean plasma elimination half-life was 2.1 h. penetration into inflammatory fluid was rapid, with mean peak levels of 91.5 mg/l occurring 0.9 h after the end of the infusion. urinary elimination accounted for 98.9% of the dose within 8 h. therapeuti ... | 2009 | 2777727 |
| pupillographic evaluation of the mydriatic effect of ibopamine solution. | the mydriatic effects of ibopamine solution at the concentrations of 0.25%, 0.50%, 1% and tropicamide solution at the concentration of 1% were evaluated in 22 clinically healthy volunteers. the study was conducted at single dose, instilling 1 drop of each concentration of ibopamine and of tropicamide in one eye and 1 drop of placebo in the other. the pupillary diameter was measured by photographic pupillography immediately before and at 10, 20, 30, 45, 60, 90, 120, 180, 240 min after each instil ... | 2009 | 2777423 |
| a survey of the human t-cell lymphotropic virus type i (htlv-i) in south-western colombia. | to evaluate altitude of birthplace and residence as factors associated with geographic clustering of htlv-i infection in colombia, we sampled a total of 670 current residents of the south pacific coastal lowland and of upland regions (cali and environs) of the valle and cauca provinces, located at an altitude of 3,100 ft. among the 255 lowland study subjects, 4.3% had antibody against htlv-i, compared to 0.9% of the 415 upland study subjects. a hypothesis emerging from this study is that the low ... | 1989 | 2777408 |
| neutralisation of the new cholera toxin by antiserum against crude enterotoxin of cholera toxin gene-positive vibrio cholerae 01 in rabbit ileal loop model. | the enterotoxicity of the new cholera toxin (nct) prepared from cholera toxin gene-negative (ct-) v. cholerae 01 strains isolated from human diarrhoeal and environmental sources was assayed in rabbit ileal loops and the toxin unit was calculated to be 24 micrograms of protein. the enterotoxicity of the nct preparations were completely neutralised by the antiserum raised against the enterotoxin preparation from the ct+ v. cholerae 01 strain 569b at 1 in 16 dilution in ileal loops. the antiserum c ... | 1989 | 2777342 |
| [unusual site of misinterpreted bone metastases in irradiated stage iib cervix cancer]. | bone metastases from cervical carcinoma are rare. their frequency is reported to be 1.9-4.6%. because of their rarity, the skeletal lesions remain inevident for a long time. a case of unusual unrecognized metastases from a stage iib cervical carcinoma, which were localized in the bones for the foot, is described. | 2009 | 2777056 |
| discordance between flow cytometric abnormalities and dysplasia in barrett's esophagus. | eighty-six specimens from 25 patients with barrett's epithelium were analyzed by both histology and flow cytometry. of these, 73 were without dysplasia and 13 had dysplasia (7 low grade, 6 high grade). eight of the nondysplastic specimens were aneuploid and another 15 had increased g2. among the dysplastic specimens, two were aneuploid and two had increased g2. these data were grouped into four classifications: type 1 (65 specimens), specialized columnar epithelium (barrett's) without dysplasia ... | 2009 | 2777038 |
| comparison of selective and complete inhibitors of enkephalin-degrading enzymes on morphine withdrawal syndrome. | we investigated the effects of thiorphan, a selective inhibitor of endopeptidase 24.11 'enkephalinase', kelatorphan ((r)-3-(n-hydroxy-carboxamido-2-benzylpropanoyl)-l-alanine), and rb 38 a ((r)-3-(n-hydroxycarboxamido-2-benzylpropanoyl)-l-phenylalanine) two almost complete inhibitors of enkephalin metabolism, on the naloxone-precipitated morphine withdrawal syndrome in rats. inhibitors administered intracerebroventricularly reduced several symptoms of the withdrawal syndrome. jumping, chewing an ... | 1989 | 2776828 |
| suppression of antibody responses to the acetylcholine receptor by natural antibodies. | some relationships between "natural" physiological autoreactivity and antibody responses against the acetylcholine receptor (achr) were investigated. collections of unselected monoclonal antibodies were derived from nonmanipulated newborn mice of susceptible (balb.b) and resistant (balb/c) mouse strains, and screened for reactivity with heterologous achr. five in 200 balb/c but none in 200 balb.b clones were found reactive. four of these anti-achr antibodies were analyzed for connectivity to nin ... | 1989 | 2776827 |
| comparative pharmacokinetics of zidovudine (azt) and its metabolite (g.azt) in healthy subjects and hiv seropositive patients. | 1989 | 2776824 | |
| comparison of trimethadione and antipyrine as indicators of oxidative drug metabolizing capacity in man. | ten healthy male volunteers were given trimethadione (tmo) 4 mg/kg and antipyrine (ap) 500 mg alone or concomitantly to determine whether the metabolism of the drugs was mediated by the same or closely related forms of cytochrome p-450. whether administered alone or together the clearance (cl) and half-life (t 1/2) of tmo and ap were the same, and there was a good correlation between the cl and t 1/2 of tmo and ap (alone r = 0.755 and 0.623, respectively; coadministered r = 0.771 and 0.503, resp ... | 1989 | 2776822 |
| in vitro determination of phagocytosis and intracellular killing of brucella melitensis by goat's polymorphonuclear phagocytes. | one hundred and forty samples of goats serum taken from animals suspected of having brucellosis, have been studied by trying to assess the phagocytosis in vitro of brucella melitensis rev-1 by polymorphonuclear neutrophil phagocytes opsonized with antibrucella serum. the serum agglutination test and the coombs antiglobulin test were carried out with the serum samples. the opsonization ingestion, intracellular killing and germ killing power of the serum were also assessed. the results demonstrate ... | 1989 | 2776406 |
| sialidase from different sources compared for electrophoretically separating serum alkaline phosphatase fractions from liver and bone. | we compared sialidase (neuraminidase; ec 3.2.1.18) from vibrio cholerae, clostridium perfringens, and arthrobacter ureafaciens, seeking to improve the electrophoretic separation of the liver and bone isoenzymes of alkaline phosphatase (ec 3.1.3.1) on cellulose acetate membranes. resolution is decisively determined by the type and activity of sialidase used in the preincubation of serum sample. sialidase from arthrobacter ureafaciens is not suited for this method. for optimal separation of the tw ... | 1989 | 2776324 |
| metabolism of platelet-activating factor (paf; 1-o-alkyl-2-acetyl-sn-glycero-3-phosphocholine) and lyso-paf (1-o-alkyl-2-lyso-sn-glycero-3-phosphocholine) by cultured rat kupffer cells. | the metabolism of platelet-activating factor (paf; identified as agepc: 1-o-alkyl-2-acetyl-sn-glycero-3-phosphocholine) and lyso-paf (lyso-gepc: 1-o-alkyl-2-lyso-sn-glycero-3-phosphocholine) was investigated in cultured rat kupffer cells. the rat kupffer cells accumulated [3h]agepc and deacetylated this compound to the corresponding [3h]lyso-gepc, which was the major metabolic product of [3h]agepc. [3h]lyso-gepc was distributed primarily in the supernatant fraction of incubated cells throughout ... | 1989 | 2775221 |
| primary structure of a novel 4-acetamido-4'-isothiocyanostilbene-2,2'-disulphonic acid (sits)-binding membrane protein highly expressed in torpedo californica electroplax. | polyclonal rabbit antibodies were raised against 4-acetamido-4'-isothiocyanostilbene-2,2'-disulphonic acid (sits), an inhibitor of a variety of anion transport proteins. these antibodies specifically recognize sits-reacted erythrocyte band 3 in immunoprecipitations and western blots. in western blots of sits-reacted membrane proteins derived from vesicles of the electric organ of torpedo californica (known to express a sits-sensitive cl- channel) the antibodies recognized two major species of ap ... | 1989 | 2775201 |
| comparative dna reassociation kinetics of cranes. | 2009 | 2775167 | |
| comparative dna reassociation kinetics of cranes. | 2009 | 2775167 | |
| arthropathy of the wrist in leprosy--what changes are caused by long-standing peripheral nerve palsy? | a radiographical screening study of 338 leprotic patients was performed. clinically, according to a nerve score (ns) designed by us, 12.9% of 674 hands showed mild nerve palsy (ns 5 or 6), 75.9% moderate (ns 3 or 4), and 11.4% severe (ns less than 2). twenty-nine hands of 26 patients (ns 4.2 on average) demonstrated abnormal changes of the wrist joint on radiographs. we classified them into four groups: (a) lunate collapse (four patients), (b) scaphoid nonunion (eight), (c) scaphoid cyst (three) ... | 2009 | 2774872 |
| cholera in louisiana. widening spectrum of seafood vehicles. | the largest cholera outbreak in the united states in over a century occurred in louisiana from august through october 1986. eighteen persons in 12 family clusters had stool culture or serologic evidence of infection with toxigenic vibrio cholerae 0-group 1. thirteen of these persons had severe diarrhea, and 4 required intensive care unit treatment. although all 18 survived, 1 96-year-old woman with suspected cholera died shortly after hospital admission. a case-control study showed that case-pat ... | 1989 | 2774784 |
| twenty-year comparison of the human allograft and porcine xenograft. | this study compares a retrospective consecutive series of human allografts and concurrent porcine xenografts implanted over a 10-year interval. there were 571 allograft valves and 1,351 xenograft valves implanted in the aortic and mitral position with mean follow-up of 12.8 years for the allografts and 6.2 years for the xenografts. this study compares the incidence of structural deterioration over long-term follow-up. we found that there was no significant difference between four manufacturers o ... | 1989 | 2774760 |
| the trigeminal (v), an oft-neglected nerve. | corneal denervation is one of the most serious insults that can occur to an eye; disease symptoms can be suppressed, and epithelial breakdown is likely to occur. in the cases presented, failure to test corneal sensation delayed diagnosis and endangered the cornea. conditions affecting the trigeminal sensory pathway, including those causing a pain-anesthesia paradox, are described. corneal sensation must be tested in all instances of suspicious head pain or paresthesia, head trauma, cranial nerve ... | 2009 | 2774430 |
| [yolk sac tumor of the ovary]. | 2009 | 2773409 | |
| stroke, hemodilution, and mortality. | 2009 | 2772989 | |
| [the fédération dentaire internationale fdi]. | 2009 | 2772600 | |
| annual reports from departments of clinical chemistry: a nordkem project. | the purpose of this report is to describe briefly the structure and purpose of nordkem, to illustrate how projects are developed within nordkem, and to discuss the results obtained in the project chosen for this presentation. | 2009 | 2772559 |
| characterization of hemoglobin variants. prenatal diagnosis on a fetus at risk of having the hemoglobin variants s and/or c in combination with beta-thalassemia. | the determination of hemoglobin types in a fetus whose father and mother were heterozygous for hb s and hb c, respectively, is used as an example for demonstrating different techniques. the parents were furthermore suspected of being heterozygous for beta-thalassemia. several of the possible combinations give rise to such serious conditions that abortus provocatus would be considered. the conclusion from the analyses was that the fetus was normal, having no variants nor thalassemia. | 2009 | 2772555 |
| [intranasal meningoceles]. | the authors present a case of intranasal meningocele in 38-year-old patient. clinical picture, diagnostics, treatment and postoperative course are described. | 2009 | 2772546 |
| epidermoid and dermoid tumors. | the authors report their experience in the surgical treatment of intracranial dermoid and epidermoid tumors. these lesions are rare but may, in most of the occasions, be completely resected allowing a complete cure of the patient. the usefulness of the most recent diagnostic tools is discussed and the surgical indications, complications and results are reviewed in comparison to the most significant literature reports. | 2009 | 2772510 |
| treatment of nasal polyps--medication or surgery and which technique. | 2009 | 2772493 | |
| recurrent polyposis nasi. plenary session, held during the 12th congress of the european rhinologic society, including the viith i.s.i.a.n. amsterdam (the netherlands), june 1988. | 2009 | 2772490 | |
| membrane fatty acids and erythrocyte li-na countertransport in nephrotic syndrome and their relationship. | cholesterol/phospholipids molar ratio and fatty acid composition have been estimated in erythrocyte membrane of 12 patients suffering from nephrotic syndrome and compared to values obtained in 23 normal subjects matched for sex and age. the membrane lipid composition has been correlated with the activity of erythrocyte li-na countertransport of the same subjects. the results show a significant increase in cholesterol/phospholipids ratio and total saturated fatty acids when erythrocytes of nephro ... | 2009 | 2772488 |
| [preparation of the colon for elective surgery]. | mechanical bowel preparation and antibiotic therapy have been conclusive to decrease morbi-mortality in elective colon surgery. two methods were compared: the traditional laxative and three days solution enemas method, and the 3-6 hours total intestinal irrigation method. we evaluated the patient's acceptance, intraoperative bowel preparation, and postoperative. we included 31 patients distributed in both groups and with similar procedures. our results showed up 80% effectiveness in colon cleani ... | 2009 | 2772480 |
| disseminated fusarial infection. | 2009 | 2772474 | |
| pseudomonas cepacia typing systems: collaborative study to assess their potential in epidemiologic investigations. | to determine the utility of available pseudomonas cepacia typing systems for confirming the relatedness of isolates, we applied these methods to isolates associated with previously investigated nosocomial outbreaks. we compared chromosome analysis, serologic reactions, biochemical tests, bacteriocin production and susceptibility, and antimicrobial susceptibility in their ability to determine outbreak relatedness. chromosome analysis, serologic reactions, and biochemical tests were each demonstra ... | 1989 | 2772466 |
| infected false aneurysms of the femoral artery in intravenous drug addicts. | the evaluation and treatment of 60 intravenous drug addicts with infected false aneurysms of the femoral artery seen at henry ford hospital (detroit) from 1977 to 1988 were retrospectively reviewed. the most common presenting signs and symptoms were groin swelling and/or mass in 56 (93%) of the patients and pain and/or tenderness in 48 (80%) of the patients. digital subtraction angiography and standard arteriography showed sensitivities of 92% and 96%, respectively, in the detection of aneurysms ... | 1989 | 2772464 |
| [the effect of cigarette smoking on the cicatrization of duodenal ulcers in patients treated with cimetidine. the role of acid hypersecretion]. | in 92 patients with duodenal ulcer, male cigarette smokers treated with cimetidine 1 g/day, 66.3% healed after four weeks. no differences were observed between healed and non-healed patients for age, symptom period before treatment, early onset (less than 30 years), multiple ulcers. in non-healed patients, more had a greater ulcer diameter (p = 0.0026) and more were heavy smokers (p = 0.0002). in non-healed patients, pentagastrin-induced maximal acid output, corrected for age, was higher than in ... | 2009 | 2772460 |
| rural nursing: developing the theory base. | many health care needs of rural dwellers cannot be adequately met through the use of existing nursing models alone but require unique approaches emphasizing the special needs of this population. the development of an integrated theory base for rural nursing is necessary. a retroductive approach, building upon both qualitative and quantitative research data, is being used to develop a theory of rural nursing. key concepts identified are: work beliefs and health beliefs; isolation and distance; se ... | 2009 | 2772454 |
| [coronarography using high-flow 5f catheters. percutaneous technic using the femoral and brachial routes]. | in order to validate 5f catheters for assessing ischemic heart disease either by the femoral and the right brachial approaches, we prospectively studied with these catheters 125 patients by means of left ventriculogram and coronary artery angiograms. twenty-five patients were studied with pigtail and amplatz catheters using the right brachial approach (group i) and 100 patients were studied by the femoral route with pigtail and judkins catheters (group ii). results were compared to those obtaine ... | 2009 | 2772365 |
| [cardiovascular risk factors in children and adolescents in fuenlabrada: objectives, features of the population, design, participation, equipment, laboratory technics, and quality control]. | fuenlabrada is at the present time the most industrialized town placed at the south are of madrid. this population has some peculiar attractive characteristics from the epidemiologic point of view. perhaps the most important is that the majority of its inhabitants are immigrant from other depressed rural areas of the country, with a low socio-economic and cultural level. the new conditions of life could have changed the life expectation and the causes of morbidity and mortality of this populatio ... | 1989 | 2772364 |
| [bronchoalveolar lavage in the diagnosis of pulmonary tuberculosis]. | 2009 | 2772330 | |
| community care--up in the air? | 2009 | 2771747 | |
| quest. nt's educational supplement. | 2008 | 2771684 | |
| erythropoietin and chronic renal failure. | 2009 | 2771635 | |
| [malignant degeneration of partial hydatidiform mole pregnancy]. | 2007 | 2771395 | |
| [fatal septum pellucidum cyst]. | case history of a patient with cysta septi pellucidi is described. pathomechanism of the symptoms and that of the fatal outcome is curtly analysed. it is stated that communicating cysta may become non-communicating one and vice versa, so in case of a known cysta when neurologic symptoms appear, causal role of it has to be considered. | 2008 | 2771394 |
| [fatal septum pellucidum cyst]. | case history of a patient with cysta septi pellucidi is described. pathomechanism of the symptoms and that of the fatal outcome is curtly analysed. it is stated that communicating cysta may become non-communicating one and vice versa, so in case of a known cysta when neurologic symptoms appear, causal role of it has to be considered. | 2008 | 2771394 |
| scrutinizing peer review. | 2009 | 2771358 | |
| effect of defocus on blur thresholds and on thresholds of perceived change in blur: comparison of source and observer methods. | the defocus levels required for normal observers to notice the first perceptible blur of a clear test target (blur threshold) and the least perceptible change in the degree of blurriness of an already blurry target (threshold of perceived change in blur) were measured using both the source and observer methods. in the source method observers viewed defocused stimuli presented on a projection screen, whereas in the observer method focused stimuli were presented to observers who were defocused usi ... | 2009 | 2771346 |
| rapid estimation of hospital charges in patients with leukemia. validation of a multivariate prediction model. | 2009 | 2770371 | |
| [psychiatric activity is always aggressive]. | 2009 | 2770234 | |
| studies in fetal wound healing: ii. a fetal environment accelerates fibroblast migration in vitro. | we have used an in vitro model of wound healing using scratches made in a confluent monolayer of fibroblasts. the effects of fetal calf and postnatal calf serum on the migration of fibroblasts were compared. differences between fetal and calf serum-incubated fibroblasts grown on coverslips were observed within 15 minutes of exposure. cells in fetal serum began to change both shape and orientation and to move into the trough created by the scratch. the fibroblasts incubated in fetal calf serum co ... | 1989 | 2769548 |
| studies in fetal wound healing: ii. a fetal environment accelerates fibroblast migration in vitro. | we have used an in vitro model of wound healing using scratches made in a confluent monolayer of fibroblasts. the effects of fetal calf and postnatal calf serum on the migration of fibroblasts were compared. differences between fetal and calf serum-incubated fibroblasts grown on coverslips were observed within 15 minutes of exposure. cells in fetal serum began to change both shape and orientation and to move into the trough created by the scratch. the fibroblasts incubated in fetal calf serum co ... | 1989 | 2769548 |
| isolation and morphological characterization of el tor cholera phages. | five bacteriophages have been isolated for phage typing of vibrio cholerae biotype el tor. the morphology of these phages has been studied by electron microscopy. | 1989 | 2769238 |
| [severe liver damage in acute circulatory failure. a clinical study of 40 cases]. | 2009 | 2768977 |