Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| formation and removal of dna adducts in target and nontarget tissues of rats administered multiple doses of 2-acetylaminophenanthrene. | 2-acetylaminophenanthrene (2-aap) is carcinogenic for the mammary gland, small intestine and ear duct in rats, but is not hepatocarcinogenic. in order to understand the tissue specificity of tumor induction, the formation and removal of dna adducts in target and nontarget tissues have been compared in rats administered 2-aap. male and female sprague--dawley rats were treated i.p. with up to four weekly doses of 5 mg 2-aap per kg body weight. 32p-post-labeling analysis of the dna from all tissues ... | 1989 | 2805226 |
| formation and removal of dna adducts in target and nontarget tissues of rats administered multiple doses of 2-acetylaminophenanthrene. | 2-acetylaminophenanthrene (2-aap) is carcinogenic for the mammary gland, small intestine and ear duct in rats, but is not hepatocarcinogenic. in order to understand the tissue specificity of tumor induction, the formation and removal of dna adducts in target and nontarget tissues have been compared in rats administered 2-aap. male and female sprague--dawley rats were treated i.p. with up to four weekly doses of 5 mg 2-aap per kg body weight. 32p-post-labeling analysis of the dna from all tissues ... | 1989 | 2805226 |
| [atypical familial hereditary degeneration of the macula]. | family case report presenting a central detachment initially associated to peripheral retinal disorders. discussion on the uniqueness of this syndrome. | 2009 | 2805214 |
| [atypical familial hereditary degeneration of the macula]. | family case report presenting a central detachment initially associated to peripheral retinal disorders. discussion on the uniqueness of this syndrome. | 2009 | 2805214 |
| adverse events temporally associated with immunizing agents: 1987 report. | 2007 | 2804852 | |
| properties of cutaneous afferents in diabetic neuropathy. | the technique of percutaneous microneurography was used to study the response properties of 68 cutaneous afferents in 8 diabetic patients and, for comparison, of 104 afferents in 12 normal control subjects. the diabetic patients were neurologically asymptomatic or had a mild sensory neuropathy. three afferent categories were studied in the diabetic subjects (rapidly adapting type ra and slowly adapting sai and saii) in response to mechanical skin stimulation and abnormal responsiveness was encou ... | 1989 | 2804617 |
| the clinical engineering budget: how to tell the boss where the dollars went. interview by michael j miller. | 2009 | 2804483 | |
| interleukin-1 enhances survival of lethally irradiated mice treated with allogeneic bone marrow cells. | interleukin-1 (il-1) enhanced the capacity of allogeneic bone marrow (bm) cells to promote survival of mice given doses of radiation (1,200 to 1,350 cgy) that are significantly higher than those generally used for bm ablation (850 to 950 cgy). three to five times greater numbers of lethally irradiated (1,200 to 1,350 cgy) c57b1/6 (h-2b) mice given 10(7) t-cell-depleted balb/c (h-2d) bm cells survived over 6 weeks if also treated with a single intraperitoneal (ip) dose of 10 micrograms il-1 20 ho ... | 2009 | 2804363 |
| interleukin-1 enhances survival of lethally irradiated mice treated with allogeneic bone marrow cells. | interleukin-1 (il-1) enhanced the capacity of allogeneic bone marrow (bm) cells to promote survival of mice given doses of radiation (1,200 to 1,350 cgy) that are significantly higher than those generally used for bm ablation (850 to 950 cgy). three to five times greater numbers of lethally irradiated (1,200 to 1,350 cgy) c57b1/6 (h-2b) mice given 10(7) t-cell-depleted balb/c (h-2d) bm cells survived over 6 weeks if also treated with a single intraperitoneal (ip) dose of 10 micrograms il-1 20 ho ... | 2009 | 2804363 |
| detection of factor x activation in humans. | a sensitive radioimmunoassay (ria) for the fragment that is liberated from factor x when this zymogen is activated by factor vii/viia-tissue factor or factor ixa was developed. antisera were raised in rabbits to a synthetic 15 amino acid peptide containing the cooh-terminal sequence of the activation fragment coupled to bovine serum albumin with glutaraldehyde. the reactivity of the antibody population obtained toward the factor x zymogen was negligible (less than 1/36,000 that of the activation ... | 1989 | 2804345 |
| detection of factor x activation in humans. | a sensitive radioimmunoassay (ria) for the fragment that is liberated from factor x when this zymogen is activated by factor vii/viia-tissue factor or factor ixa was developed. antisera were raised in rabbits to a synthetic 15 amino acid peptide containing the cooh-terminal sequence of the activation fragment coupled to bovine serum albumin with glutaraldehyde. the reactivity of the antibody population obtained toward the factor x zymogen was negligible (less than 1/36,000 that of the activation ... | 1989 | 2804345 |
| [studies on tissue distribution of unusual estrogen-binding protein in rats with the help of immunoblotting]. | tissue distribution in male and female rats of unusual immunoreactive material specific for the hepatic estrogen-binding protein (uebp) was studied by means of immunoblotting analysis. from 28 organs and tissues studied only the liver of animals of both sexes was found to contain polypeptide with mr, close to mr of purified uebp (approximately 31,000), which reacts with anti-uebp specific antiserum. detection of the immunoreactive material in female liver, which does not contain any hormone-bind ... | 1989 | 2804329 |
| [studies on tissue distribution of unusual estrogen-binding protein in rats with the help of immunoblotting]. | tissue distribution in male and female rats of unusual immunoreactive material specific for the hepatic estrogen-binding protein (uebp) was studied by means of immunoblotting analysis. from 28 organs and tissues studied only the liver of animals of both sexes was found to contain polypeptide with mr, close to mr of purified uebp (approximately 31,000), which reacts with anti-uebp specific antiserum. detection of the immunoreactive material in female liver, which does not contain any hormone-bind ... | 1989 | 2804329 |
| basal ganglia regional glucose metabolism asymmetry during a catatonic episode. | 2009 | 2804192 | |
| basal ganglia regional glucose metabolism asymmetry during a catatonic episode. | 2009 | 2804192 | |
| a case report of acute obstructive suppurative cholangitis in a non-0-1 vibrio cholerae biliary carrier. | a case report is presented of a 73-year-old male who was seen with fever, jaundice, abdominal pain and central nervous system depression. he failed to respond to intensive antibiotic therapy, and subsequently acute obstructive suppurative cholangitis fully developed. upon laparotomy, the patient's gallbladder was found to be enlarged with the bile from the gallbladder and bile duct itself containing a high pus content. its cultured organism revealed non-0-1 vibrio cholerae. to our knowledge, no ... | 1989 | 2802912 |
| hemagglutination and intestinal adherence properties of clinical and environmental isolates of non-o1 vibrio cholerae. | hemagglutination and intestinal adherence properties of non-o1 vibrio cholerae were studied in vitro. no definite correlation between the cell-associated hemagglutinin titers and the intestinal adhesion indices was noted. sugar- and glycoprotein-mediated inhibition data also indicated differences between the hemagglutination and adherence processes in respect to the receptor structures. intestinal adherence of most v. cholerae strains could be inhibited to various extents by n-acetyl d-glucosami ... | 1989 | 2802613 |
| diagnosis of gastrinoma: much ado about nothing? | 2010 | 2802429 | |
| concurrent administration of ciprofloxacin and potentially interacting drugs. | 2010 | 2801707 | |
| how doctor's advice is followed by mothers of atopic children. | 2009 | 2800905 | |
| [diabetic autonomic neuropathy]. | affection of the vegetative nervous system is a relatively frequent and often serious complication of diabetes. the aetiopathogenesis of diabetic autonomous neuropathy has not been reliably explained so far, most probably metabolic changes are involved resulting from prolonged hyperglycaemia. a part played by other e.g. congenital factors cannot be ruled out. autonomous neuropathy can influence the function of the cardiovascular, digestive, urogenital and other systems and cause difficult diagno ... | 2009 | 2800365 |
| [cholelithiasis complicated by cholecysto-colonic fistula]. | 2006 | 2800167 | |
| comparative study of the circadian rhythmicity in the urinary concentration of glycosaminoglycans in patients of calcium oxalate nephrolithiasis and in healthy adults. | glycosaminoglycans (gags) are potent inhibitors of calcium oxalate crystallisation and/or crystal aggregation. urinary concentration of gags has been shown to vary during 24 h; therefore, circadian rhythmicity in urinary concentration of gags was investigated in 33 healthy male adults in the age group of 20-40 years and in 27 male patients of a similar age group with calcium nephrolithiasis. three-hourly urine samples were collected for 24 h beginning from 00.00 h for estimation of urinary conce ... | 2008 | 2800054 |
| [obstruction of a naso-tracheal tube by an avulsed nasal concha]. | avulsion of a nasal concha by a nasotracheal tube obstructed the tube in a valvelike manner. the result was increased intrapulmonary pressure, hemodynamic instability, alveolar rupture, pneumomediastinum and pneumoperitoneum without pneumothorax. the case was successfully managed by removal of the nasotracheal tube and immediate oral reintubation. | 2005 | 2799996 |
| [rehabilitation following arthroscopic interventions]. | the view that postoperative treatment is unnecessary after arthroscopically controlled operations is mistaken. on the contrary, the success of an arthroscopic operation depends to a large extent on effective after-treatment. arthroscopic operations can be divided into three main groups: group i partial and complete meniscectomies, removal of floating bodies, plica resection, lateral incision of the retinaculum group ii synovectomy, shaving, and chondroplasty group iii meniscus refixation, replac ... | 2009 | 2799730 |
| survival of vibrio cholerae in african domestic water storage containers. | although much has been published about growth of vibrio cholerae in natural sources of water, little or nothing has been written on its survival in common household water storage containers. this study compared the behaviour of the el tor and classical biotypes of v. cholerae in different containers commonly used in africa for domestic water storage. these included traditional clay pots, wooden barrels, galvanised iron drums (corroded and non-corroded) and plastic (polyethylene) drums. the findi ... | 1989 | 2799584 |
| [tuberculosis of the lymph nodes and spleen preceding hodgkin's disease]. | tuberculosis of the lymph nodes is not rare today. however tuberculosis of the spleen has been very rare even in the past when many patients had suffered from tuberculosis. the appearance of hodgkin's disease following tuberculosis is an extremely rare condition. it has thought that deficiency of cellular immunity was responsible for both tuberculosis and malignancy. we present a 44-year-old man in whom lymph node and spleen tuberculosis antedated the clinical onset of hodgkin's disease for thre ... | 1989 | 2799551 |
| a breath of fresh air--respiratory control demystified. | 2006 | 2799065 | |
| the activity of phosphoenolpyruvate carboxykinase throughout the lactation cycle of the guinea pig mammary gland. | the enzyme phosphoenolpyruvate carboxykinase (pepck) has been measured in the guinea pig mammary gland throughout the pregnancy-lactation cycle. this is of interest since the primary importance of pepck is thought to be its role in gluconeogenesis and it is questionable whether or not gluconeogenesis occurs in the mammary gland. the enzyme activity, present in both the cytosol and mitochondria, was shown to follow the lactation profile. during the transition into lactation, cytosolic pepck activ ... | 1989 | 2798434 |
| the activity of phosphoenolpyruvate carboxykinase throughout the lactation cycle of the guinea pig mammary gland. | the enzyme phosphoenolpyruvate carboxykinase (pepck) has been measured in the guinea pig mammary gland throughout the pregnancy-lactation cycle. this is of interest since the primary importance of pepck is thought to be its role in gluconeogenesis and it is questionable whether or not gluconeogenesis occurs in the mammary gland. the enzyme activity, present in both the cytosol and mitochondria, was shown to follow the lactation profile. during the transition into lactation, cytosolic pepck activ ... | 1989 | 2798434 |
| medical students' desire to avoid aids patients stems chiefly from fear of contagion, study shows. | 2009 | 2798276 | |
| medical students' desire to avoid aids patients stems chiefly from fear of contagion, study shows. | 2009 | 2798276 | |
| greed in healthcare. | 2009 | 2798274 | |
| greed in healthcare. | 2009 | 2798274 | |
| early clinical results of the ttap acetabular cup. | one hundred seventy-five threaded titanium alloy prostheses (ttap) acetabular cups and 125 cemented cups were evaluated clinically and radiographically at 1 to 3 years postoperatively. the series was statistically different in that there were more women in the cemented group than in the non-cemented group (p less than .001). the cemented group was also older than the threaded group (p less than .001). pain, ambulation, function, range of motion, and roentgenograms were evaluated in all patients. ... | 2009 | 2798250 |
| early clinical results of the ttap acetabular cup. | one hundred seventy-five threaded titanium alloy prostheses (ttap) acetabular cups and 125 cemented cups were evaluated clinically and radiographically at 1 to 3 years postoperatively. the series was statistically different in that there were more women in the cemented group than in the non-cemented group (p less than .001). the cemented group was also older than the threaded group (p less than .001). pain, ambulation, function, range of motion, and roentgenograms were evaluated in all patients. ... | 2009 | 2798250 |
| descriptive studies on narcissistic personality disorder. | this article describes a series of empirical studies on narcissistic disturbances and the narcissistic personality disorder in psychiatric patients. the work began with a survey of the literature and a comparison of three diagnostic systems for narcissistic personality disorder that helped clarify the degree of concordance among the existing systematic descriptions. this work gave rise to the development of a semistructured interview: the diagnostic interview for narcissism. this tool was then u ... | 2009 | 2798198 |
| descriptive studies on narcissistic personality disorder. | this article describes a series of empirical studies on narcissistic disturbances and the narcissistic personality disorder in psychiatric patients. the work began with a survey of the literature and a comparison of three diagnostic systems for narcissistic personality disorder that helped clarify the degree of concordance among the existing systematic descriptions. this work gave rise to the development of a semistructured interview: the diagnostic interview for narcissism. this tool was then u ... | 2009 | 2798198 |
| nurse--patient agreement on goals. | 2009 | 2798175 | |
| nurse--patient agreement on goals. | 2009 | 2798175 | |
| the nhs--an opportunity for coshh consciousness? | 2009 | 2797659 | |
| issues affecting the future of dentistry. | 2010 | 2797616 | |
| how can i assure collection of my fees? | 2010 | 2797615 | |
| krüppel requirement for knirps enhancement reflects overlapping gap gene activities in the drosophila embryo. | segmental pattern formation in drosophila proceeds in a hierarchical manner whereby the embryo is stepwise divided into progressively finer regions until it reaches its final metameric form. maternal genes initiate this process by imparting on the egg a distinct antero-posterior polarity and by directing from the two polar centres the activities of the zygotic genes. the anterior system is strictly dependent on the product of the maternal gene bicoid (bcd), without which all pattern elements in ... | 2009 | 2797151 |
| [monoclonal antibodies to antigens of cholera vibrios of the ogava serovar]. | a set of hybrids is obtained synthesizing monoclonal antibodies to the surface antigenic determinants of the choleric vibrio of the ogava serovar. the antigenic structure of vibrios of the typical and atypical strains isolated from a man and from environmental objects is studied using a collection of highly specific immunoglobulins. the high-specific diagnostic preparations for identification of the 01-group cholera agent serovar may be created on their base. | 1989 | 2796789 |
| [causes of unsatisfactory results of the treatment of chronic ischemia of the lower limbs using g. a. ilizarov's method]. | the g. a. ilizarov's method was used for the treatment of 46 patients with occlusion of the arteries of the lower extremities at stages iii and iv of ischemia. the treatment has proved to be ineffective in 10 patients. the use of a method in active aggravation of the inflammatory-necrotic process, postoperative arterial spasm and thrombosis, excess in the permissible rate of the bone split distraction, wrong choice of the level of osteotomy were the main causes of unsatisfactory outcomes. | 2010 | 2796170 |
| mutation induced by vibriophage ps166 infection changes biotype and phage type of vibrio cholerae. | the effect of a newly isolated vibriophage, ps166, on vibrio cholerae (e1 tor) mak757 was investigated. two ps166-resistant mutants of strain mak757 were isolated. these had undergone transition to the classical biotype with concomitant acquisition of new phage sensitivity. however, the parental ogawa serotype remained unchanged. these mutant strains also showed a unique temperate phage-sensitivity profile, distinct from that of strain mak757. the possible target of phage ps166 interaction is di ... | 1989 | 2795637 |
| the temporomandibular ligament and the articular eminence as constraints during jaw opening. | it is generally thought that during symmetrical jaw opening the mandible rotates about an axis passing through the centres of the two mandibular condyles, and translates down the articular eminence. the author argues that there are no data to support this assumption. the true combination of movements can only be understood by understanding the constraints that operate during jaw opening and these are the articular eminence and the temporomandibular (tm) ligament. the tm ligament is pulled taut d ... | 2009 | 2795311 |
| immune thrombocytopenia in aids patients: case report. | 2009 | 2795303 | |
| diffraction by a circular aperture as a model for three-dimensional optical microscopy. | existing formulations of the three-dimensional (3-d) diffraction pattern of spherical waves that is produced by a circular aperture are reviewed in the context of 3-d serial-sectioning microscopy. a new formulation for off-axis focal points is introduced that has the desirable properties of increased accuracy for larger field angles, invariance to shifts of the focal point about spheres of constant radius when the detection point is on the sphere for both intensity and amplitude fields, and inva ... | 2009 | 2795290 |
| heterochromatic modulation photometry. | heterochromatic modulation photometry is a method for obtaining equiluminance for a pair of heterochromatic lights presented in temporal alternation. a series of fixed standard luminance/test luminance ratios are presented, and at each ratio the modulation depth of the pair is reduced in tandem until the observer reports that flicker disappears. the data can be described by a luminance contrast template that appears v shaped when plotted on log-log coordinates. in the fitting of individual data, ... | 2009 | 2795287 |
| reversal of rejection-induced coronary vasculitis detected early after heart transplantation with increased immunosuppression. | four patients who underwent heart transplantation, in whom coronary obstruction was seen early after transplantation, are described. repeated acute rejection episodes were detected within the first 2 months in each patient. coronary obstruction or ischemia was shown through a combination of t1-201 isotopic study findings, evidence of vasculitis of a small coronary arteriole seen at endomyocardial biopsy, or coronary angiographic results. vigorous treatment for rejection (antithymocyte globulin a ... | 2009 | 2795284 |
| rehabilitation of atrophied muscle in the rheumatoid arthritic hand: a comparison of two methods of electrical stimulation. | this study compares the effectiveness of two therapeutic electrotherapies which result in plastic adaptation in the atrophied muscle of rheumatoid arthritic hands. the natural discharge pattern of a fatigue-resistant motor unit (eutrophic electrotherapy) was more effective than a uniform 10 hz electrotherapy. it was concluded that uniform 10 hz electrotherapy ignored the information carried in the motor unit action potential spike train, which was the signal inducing rapid and behaviourally effe ... | 2009 | 2794708 |
| a case of non-o:1 vibrio cholerae bacteremia from northern europe. | 1989 | 2794570 | |
| elevation of factor vii activity and mass in young adults at risk of ischemic heart disease. | the northwick park heart study found that elevation of factor vii in middle-aged subjects was an independent risk factor for subsequent ischemic heart disease. the present study was designed to determine whether factor vii elevation is present at a younger age and whether zymogen or activated factor vii is responsible for this elevation. a group of 20 asymptomatic first degree relatives (mean age 34.9 years) of patients with premature ischemic heart disease were compared with 15 age-matched norm ... | 2009 | 2794283 |
| mechanisms of arterial thrombosis in nonparallel streamlines: platelet thrombi grow on the apex of stenotic severely injured vessel wall. experimental study in the pig model. | the role of thrombosis in various acute coronary syndromes has been established. however, the basic mechanism by which plaque rupture leads to a growing thrombus in the vicinity of stenotic lesions is not well understood. using a characterized flow chamber in a rheologically controlled system, we have mimicked stenotic vessels and studied for the first time cell-vessel wall interaction in nonparallel streamlines. stenoses ranging from 0 to 80% were produced with stripped tunica media to mimic se ... | 1989 | 2794050 |
| arylsulphatase in echinoderm immunocompetent cells. | two peaks of arylsulphatase activity were detected biochemically in coelomocyte lysate preparations of seven different echinodermata species. both peaks were inactivated by sulphite and sulphate ions, indicating that type ii arylsulphatase is present in the coelomocytes of the species tested. arylsulphatase was localized histochemically in the granules of spherula cells, suggesting that in echinoderms a common cell type with granulocyte-like functions is present. the enzyme was also localized in ... | 2009 | 2793527 |
| vocational integration for the psychiatrically disabled. | 2007 | 2793094 | |
| [maternal cocaine abuse and effects on the mother, fetus and newborn]. | 2009 | 2792938 | |
| [maternal cocaine abuse and effects on the mother, fetus and newborn]. | 2009 | 2792938 | |
| outcome after discontinuation of antiepileptic drug therapy in children with epilepsy. | we studied recurrence risks and predictive factors of relapse after antiepileptic drug (aed) discontinuation in a prospective analysis of 425 children with epilepsy who had not had a seizure for at least 2 years (follow-up after withdrawal 1.6-12 years, mean 8 years). factors closely related by multivariate analysis to relapse were neurologic abnormalities, mental retardation, seizure type (infantile spasms, absence seizures), and appearance or persistence of eeg abnormalities during the course ... | 2005 | 2792033 |
| interaction of filipin with dimyristoylphosphatidylcholine membranes studied by 2h-nmr, circular dichroism, electronic absorption and fluorescence. | interaction of the pentene antibiotic filipin with dimyristoylphosphatidylcholine (dmpc) membranes has been monitored by 2h-nmr, circular dichroism (cd), electronic absorption and fluorescence in the temperature range 10 degrees to 60 degrees c. interaction appears to depend on whether filipin is added before or after membrane formation and also upon the temperature of the system. when filipin is added to preformed dmpc large unilamellar vesicles (luv), the association constants, as determined b ... | 2003 | 2792024 |
| bolus injections of recombinant human interleukin-1 cause transient hypocalcemia in normal mice. | single daily injections of recombinant human interleukin-1 alpha (il-1 alpha) or interleukin-1 beta (il-1 beta) were given for 1-3 days to normal mice, and blood ionized calcium concentrations were measured before and at various times after each injection. mean blood calcium levels fell significantly in both groups of animals 3 h after the first il-1 injections and returned to pretreatment values at 5 h. however, at 24 and 48 h mean values were significantly higher than those in saline-heated co ... | 1989 | 2792008 |
| interaction between prostatic fibroblast and epithelial cells in culture: role of androgen. | we have established and characterized two cell lines from the ventral prostate gland of normal nb rats: nbe-1 (prostatic epithelial) and nbf-1 (prostatic fibroblast) cell lines. to identify the direct mitogenic action of dihydrotestosterone (dht), we incubated these cell lines alone and together (in the presence and absence of cell contact) with various concentrations of dht (0.1-10,000 ng/ml) for 24-72 h and assayed for the rate of dna synthesis and the total number of cells in tissue culture a ... | 1989 | 2792005 |
| visual evoked potentials in prader-willi syndrome. | oculocutaneous, electrophysiological, and cytogenetic factors were evaluated in 14 patients with prader-willi syndrome and in three controls, two albinos and a normal observer. in a substantial number of pw patients chromosomal anomalies, particularly deletions of the long arm of chromosome 15 as well as hypopigmentation of hair, skin, and eye have been identified. in the genetic condition of albinism, hypopigmentation related to neural ectoderm derivatives is associated with reduced visual acui ... | 1989 | 2791841 |
| [ferric ammonium citrate as virulence-enhancing agent in the toxicity test of vibrio cholerae and the potency assay of cholera vaccine]. | using icr strain mice as experimental animals, 0.25% (w/v) ferric ammonium citrate (fac) was a suitable substitute for 5% (w/v) mucin as a virulence-enhancing (ve) agent in the toxicity test of vibrio cholerae and the potency assay of cholera vaccine. there was no significant lethal toxicity difference between 0.25% fac and 5% mucin as ve agents on vibrio cholerae in mice. by using 0.25% fac as a ve agent in estimating the potency of cholera vaccine, the relative potency (r.p.) of the tested cho ... | 1989 | 2791724 |
| intensive care for patients with pneumocystis carinii pneumonia and respiratory failure. are we prepared for our new success? | 1989 | 2791661 | |
| enticements for fruitless bronchoscopy. | 2003 | 2791659 | |
| is etoposide injection a vesicant? | 2008 | 2791480 | |
| is etoposide injection a vesicant? | 2008 | 2791480 | |
| automated record linkage: a response to the commentary and letters to the editor. | 2009 | 2791442 | |
| the homogeneous nature of the hemolytic uremic syndrome. | 2009 | 2791440 | |
| effect of platelet factors on migration of cultured bovine aortic endothelial and smooth muscle cells. | endothelial cell (ec) injury and the response of ec and smooth muscle cells (smcs) to injury contribute to the pathophysiology in patients with vascular disease and atherosclerosis. since platelets have been suggested to play an important role in modulating vascular injury, the present study was undertaken to examine the influence and mechanism of action of individual platelet factors on bovine aortic ec and smc migration using an in vitro wound assay system. serotonin decreased ec proliferation ... | 1989 | 2791219 |
| relative contribution of various forms of cytochrome p450 to the metabolism of benzo[a]pyrene by human liver microsomes. | a variety of cytochromes p450 have been implicated in the hepatic metabolism of benzo[a]pyrene (bp), including forms that are constitutively expressed and those that are highly inducible. in the present study the metabolism of bp to organic solvent-soluble derivatives by eight forms of cytochrome p450 isolated from rat liver and by a series of 11 human liver microsomal samples was investigated. the relative contribution of specific p450 forms to the human hepatic metabolism was evaluated. a 4-fo ... | 1989 | 2791199 |
| [clinical and experimental research on a kidney-tonifying prescription in preventing and treating children's hearing-loss induced by aminoglycoside antibiotic ototoxicity]. | this paper reports 30 cases of hearing-loss induced by aminoglycoside antibiotic ototoxicity treated mainly with kidney-tonifying herbs such as herba epimedii, rhizoma drynariae, rhizoma polygonati, radix polygoni multiflori, magnetitum and rhizoma acori graminei, etc. after three month's treatment, the authors found that 19 cases had improved their hearing more than 15 db, among which there are 8 cases who had improved 15 db and 11 cases 30 db. the patients' hearing of pre-treatment and post-tr ... | 1989 | 2791158 |
| [extramedullary nodular plasmocytic lymphoma]. | a plasmacytic lymphoma of the cervical nodes in a 71-year-old women spread also to the mediastinal nodes and after two years proved fatal. the authors did not detect a rise of monoclonal serum immunoglobulins nor did they detect their presence in the cytoplasm of tumour cells in the nodes subjected to biopsy. the lymphoma was preceded by a specific granulomatous inflammation of the skin and nodes persisting for four years. | 2009 | 2790896 |
| be wary of wrongful-dismissal suits. | 2009 | 2790610 | |
| squamous cell carcinoma of the base of the tongue: results of treatment in 115 cases. | between 1976 and 1986, we treated 115 patients (mean age 53.8 years) with base of tongue carcinomas. the staging system used was the uicc tnm classification of 1979. seventy per cent of the tumours were t3 or t4 and 42% had n2 or n3 lymph node. locoregional treatment was irradiation alone (98/115) or surgery and post-operative radiotherapy (17/115). sixty-seven patients received induction chemotherapy. actuarial survival of the entire group at 3 and 5 years was 25 and 23%, respectively, and 3-ye ... | 1989 | 2790426 |
| organ doses from cardiac and carotid digital subtraction angiography. | estimates of mean organ doses from cardiac and carotid digital subtraction angiography (dsa) are obtained from measurements done using a rando-alderson tissue-equivalent phantom. thermoluminescent dosemeter chips and discs were calibrated and used for all measurements in the primary and scattered radiation fields. skin doses as well as mean doses received by the thyroid, lung, lens of the eye, breast, uterus and the ovaries were measured. a 30 degree right anterior oblique (rao) cardiac dsa stud ... | 2004 | 2790424 |
| regional pain syndrome. | 2009 | 2790410 | |
| potentiation by vestibular stimulation of the immobility reflex elicited by clamping in developing and adult rats. | we have previously described (exp. neurol., 97: 315-326, 1987) that clamping of the neck elicits a profound immobility with flexion of limbs and ventroflexion of head and neck ('carrying posture'). we also observed that when a clamped rat pup is carried by the experimenter's hand, such carrying posture was potentiated. in the present paper we observed that in adult rats vestibular stimulation by circular acceleration potentiates the duration of immobility reflex by clamping and intensifies the l ... | 1989 | 2789702 |
| on suicide statistics. | the classical methodological problem of suicidology is reliability of official statistics. in this article, some recent contributions to the debate, particularly concerning the increased problem of suicide among inuit, are reviewed. secondly the suicide statistics of greenland are analyzed, with the conclusion that the official statistics, as published by the danish board of health, are generally reliable concerning greenland. | 2009 | 2789569 |
| effect of vitamin d metabolites on calcitriol metabolism in experimental renal failure. | previous studies from our laboratory have demonstrated that metabolic clearance rate (mcr) of calcitriol is decreased in experimental renal failure. in this experiment, we examined the effects of calcitriol, 25-hydroxyvitamin d3 (25(oh)d3) and 24,25-dihydroxyvitamin d3 (24,25(oh)2d3) on the mcr of calcitriol in renal failure produced in rats by partial nephrectomy. the mcr of calcitriol in these rats with renal failure was significantly lower than in control rats with sham operations. plasma con ... | 1989 | 2789310 |
| clinicopathologic spectrum of cutaneous manifestations in systemic follicular lymphoma. a study of 11 patients. | follicular lymphoma is rarely diagnosed on the basis of only a cutaneous biopsy. eleven patients with primary follicular lymphoma of lymph nodes who developed skin lesions were studied. skin lesions involved the scalp, head and neck, trunk, and buttocks and were small cleaved cell type in four cases, large cell type in three cases, and mixed type in four cases. the follicular pattern with a bottom-heavy distribution was identified in only six of the 11 cases. one case showed a nodular, perivascu ... | 2009 | 2789095 |
| a t-cell-specific transcriptional enhancer element 3' of c alpha in the human t-cell receptor alpha locus. | a transcriptional enhancer element has been identified 4.5 kilobases 3' of c alpha (constant region alpha chain) in the human t-cell receptor (tcr) alpha-chain locus. this enhancer is active on both a tcr v alpha (variable region alpha chain) promoter and the minimal simian virus 40 promotor in tcr alpha/beta jurkat and el4 cells but is inactive on a v alpha promoter in human tcr gamma/delta peer and molt-13 cells, clone 13 b cells, and hela fibroblasts. the enhancer has been localized to a 116- ... | 1989 | 2788889 |
| [cardiosurgical intervention in coronary heart disease]. | 2002 | 2788772 | |
| cardiovascular and metabolic responses during anoxic submergence in the bullfrog with and without maintained extracellular ph. | we studied metabolic, cardiovascular, and electrolyte responses of paralyzed bullfrogs to 6 hours of submerged anoxia at 15 degrees c, either with or without maintenance of extracellular ph at preanoxic values by nahco3 infusion. there were no differences in arterial pco2 between acidemic and nonacidemic groups. lactate appearance in arterial blood, as an indicator of anaerobic metabolic rate, was not significantly different between the anoxic groups, although both were significantly elevated ov ... | 2009 | 2788711 |
| hierarchy of cytotoxic t cell clones. i. reversal of resistance to lysis and killing between anti-hapten cytotoxic t cells. | cells from clones of anti-hapten cytotoxic t lymphocytes (ctl) can act as both effector cells and, when treated with the specific hapten, as target cells. individual clones can kill haptenated cells only from other clones that are less efficient killers. clones specific for both fluorescein and trinitrophenol could be ordered in a single hierarchy in which resistance to lysis correlated with lytic efficiency. when the killing efficiency was reduced with phorbol myristate acetate (pma) or the col ... | 2009 | 2788518 |
| effect of doxorubicin on mouse hybridoma b cells: stimulation of immunoglobulin synthesis and secretion. | the purpose of these studies was to investigate whether the cell-differentiating effect of anthracyclines can trigger an over-production and secretion of molecules that may interfere with the tumor-host relationship. we exposed mouse hybridoma b-cells, which are devoted to immunoglobulin production, to doxorubicin (10-40 ng/ml). we found that most doxorubicin-treated cells secreted 3- to 5-fold higher amounts of immunoglobulin than untreated cells, along with an accumulation of 50% of them in th ... | 1989 | 2788496 |
| the epidemiology of panic symptomatology and agoraphobic avoidance. | in a random community survey of 1,498 urban adults age 18 to 64 years who were interviewed using the diagnostic interview schedule (dis), the lifetime prevalence of panic disorder was 2.2% +/- 0.4%. this was higher in women (3.4% +/- 0.7%) than in men (0.9% +/- 0.6%), and in those under the age of 45 years. lifetime prevalence for panic attacks was 7.8% +/- 0.7%. panic attacks and panic disorder had a similar distribution by age and sex, with higher rates in women than men, and also in the under ... | 2009 | 2788067 |
| neoplasms in dialysis patients: a population-based study. | cancer incidence was assessed in 4,161 end-stage renal disease (esrd) patients on dialysis to determine whether there was any excess risk of cancer in this population. records from the michigan kidney registry (mkr) for 1973 to 1984 were linked to those of the michigan cancer foundation's metropolitan detroit cancer surveillance system (mdcss) to identify cases in the dialysis cohort. the expected number of cancers in the esrd population was calculated using the race-, sex-, age- and calendar ye ... | 2009 | 2787957 |
| inhibition of enteropathogenic bacteria by human milk whey in vitro. | diarrhea caused by enteropathogenic bacteria is a leading cause of childhood mortality world-wide, particularly in less developed regions. breast-feeding has been advocated to protect infants and children from infectious illnesses. we examined the antibacterial activity of human whey in vitro against multiple strains of the following species of enteropathogenic bacteria, campylobacter jejuni, escherichia coli, salmonella typhimurium, shigella flexneri, shigella sonnei and vibrio cholerae, all is ... | 1989 | 2787902 |
| differential exposure of the major gangliosides in rabbit thymocytes to vibrio cholerae neuraminidase. | neuraminidase treatment of lymphocytes is known to cause changes of cellular responses in several biological phenomena, but the molecules modified on the cell surface by neuraminidase are not known in detail. rabbit thymocytes, which contain tissue-characteristic gangliosides, were treated with vibrio cholerae neuraminidase, and the susceptibility of the cell surface sialic acid residues was examined. the amount of sialic acid released from the thymocytes at the highest level was 42.4 nmol per 1 ... | 1989 | 2787793 |
| effect of protein kinase c inhibitor (h-7) and calmodulin antagonist (w-7) on pertussis toxin-induced il-1 production by human adherent monocytes. comparison with lipopolysaccharide as a stimulator of il-1 production. | human adherent monocytes stimulated with 1 microgram/ml pertussis toxin (pt) produced interleukin-1 (il-1), as measured by thymocyte co-stimulation assay and enzyme-linked immunosorbent assay (elisa), specific for il-1 alpha and il-1 beta. to clarify the role of protein kinase c (pkc) and calmodulin in il-1 production, we investigated the effects of a pkc inhibitor, h-7, and a calmodulin antagonist, w-7 on pt- and lipopolysaccharide (lps)-induced il-1 production by monocytes. addition of 10 micr ... | 1989 | 2787778 |
| an alternative cytoplasmic domain of the integrin beta 3 subunit. | a cdna encoding a new form of the shared beta subunit (beta 3) of the platelet integrin gpiib/iiia and the vitronectin receptor was isolated from a placental cdna library by screening with a beta 3 (gpiiia) dna probe. this beta 3 variant differs from the previously reported beta 3 in that the cytoplasmic domain is 8 amino acids shorter and has an alternative, 13-amino acid cooh-terminal peptide. the 3' untranslated region of the cdna also differs from the previously reported sequence, while the ... | 1989 | 2787511 |
| abnormalities in growth characteristics of aortic smooth muscle cells in spontaneously hypertensive rats. | comparative studies have shown that cultured vascular smooth muscle cells from spontaneously hypertensive rats (shr) proliferate to a higher cell number, grow to a greater density, and have greater specific growth rate, particularly at a higher saturation density, than those of the normotensive wistar-kyoto (wky) control rats. the growth difference was not due to varying cell survival nor to attachment ability after passage. the degree of dna synthesis was estimated by [3h]thymidine incorporatio ... | 1989 | 2786847 |
| systemic delayed-type hypersensitivity to cholera toxin and a detoxified derivative. | the delayed-type hypersensitivity (dth) response to cholera toxin (ct) and an immunopurified formalinized toxoid (td) was studied in adult balb/c mice. intradermal injection of ct in non-immune animals produced substantial footpad oedema which interfered with the measurement of specific dth but td proved satisfactory as a challenge antigen. dth to ct was induced by doses ranging from 0.1 to 10 micrograms, in complete freund's adjuvant (cfa). the optimal reaction was primed for by 1 microgram ct. ... | 1989 | 2786775 |
| [ambulatory care and treatment of children with rheumatoid uveitis]. | the paper presents data on dispensarization and out-patient treatment of 43 children with rheumatoid uveitis. thanks to a well-composed system of observation over the patients and their corresponding treatment, including antirecurrent therapy, under control of immunologic investigations stabilization of the process was achieved in 17 children, improvement of clinical state of the eye and its visual functions--in 10 persons. all children with rheumatoid uveitis require dispensarization under cons ... | 2009 | 2786614 |
| a technique for using ct images in attenuation correction and quantification in spect. | a technique is described for using computed tomography (ct) images for attenuation correction and quantification in spect. the ct images are aligned with the corresponding spect slices and the hounsfield units are converted to linear attenuation coefficient values for the spect radionuclide. the attenuation coefficient map thus produced is used to provide the attenuation correction required in the spect reconstruction. the technique has been evaluated in both a non-anatomical and an anatomical p ... | 2009 | 2786613 |
| [single photon emission computed tomography by using n-isopropyl-p-[123i]-iodoamphetamine and 99mtc-hexamethyl propyleneamine oxime in a patient with herpes simplex encephalitis]. | single photon emission computed tomographies (spects) by using n-isopropyl-p-[123i-imp]-iodo-amphetamine (123i-imp) and 99mtc-hexamethyl propyleneamine oxime (99mtc-hm-pao) were serially performed in a 70 yrs. old male with herpes simplex encephalitis (hse), and the chronological changes of accumulations were studied. accumulations of both 123i-imp and 99mtc-hm-pao increased initially, and then decreased with the stage of hse being advanced. the sequential appearance of the lesion in hse with 12 ... | 2009 | 2786584 |