Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| from information theory to quantitative description of steric effects. | immense efforts have been made in the literature to apply the information theory descriptors for investigating the electronic structure theory of various systems. in the present study, the information theoretic quantities, such as fisher information, shannon entropy, onicescu information energy, and ghosh-berkowitz-parr entropy, have been used to present a quantitative description for one of the most widely used concepts in chemistry, namely the steric effects. taking the experimental steric sca ... | 2016 | 27321125 |
| defining the limits and reliability of rigid-body fitting in cryo-em maps using multi-scale image pyramids. | cryo-electron microscopy provides fascinating structural insight into large macromolecular machines at increasing detail. despite significant advances in the field, the resolution of the resulting three-dimensional images is still typically insufficient for de novo model building. to bridge the resolution gap and give an atomic interpretation to the data, high-resolution models are typically placed into the density as rigid bodies. unfortunately, this is often done manually using graphics softwa ... | 2016 | 27318041 |
| reduction and sustainability of cesarean section surgical site infection: an evidence-based, innovative, and multidisciplinary quality improvement intervention bundle program. | we found cesarean section (c-section) surgical site infection (ssi) at our institution was significantly higher than the national benchmark. | 2016 | 27317407 |
| immunoexpression of epithelial mesenchymal transition proteins e-cadherin, β-catenin, and n-cadherin in oral squamous cell carcinoma. | aims epithelial mesenchymal transition (emt) is a crucial process for acquisition of malignant phenotype, aggressiveness, and metastatic capacity in neoplasms. it is characterized by loss of epithelial markers and gain of mesenchymal markers. studies on emt and its potential association with the histological grading are sparse in oral squamous cell carcinoma (oscc). this study aims to evaluate the expression of emt-associated proteins-e-cadherin, β-catenin, and n-cadherin-in different grades of ... | 2016 | 27312520 |
| argon: fast, whole-genome simulation of the discrete time wright-fisher process. | simulation under the coalescent model is ubiquitous in the analysis of genetic data. the rapid growth of real data sets from multiple human populations led to increasing interest in simulating very large sample sizes at whole-chromosome scales. when the sample size is large, the coalescent model becomes an increasingly inaccurate approximation of the discrete time wright-fisher model (dtwf). analytical and computational treatment of the dtwf, however, is generally harder. | 2016 | 27312410 |
| cerebral microbleeds in multiple sclerosis evaluated on susceptibility-weighted images and quantitative susceptibility maps: a case-control study. | purpose to assess cerebral microbleed (cmb) prevalence in patients with multiple sclerosis (ms) and clinically isolated syndrome (cis) and associations with clinical outcomes. materials and methods cmbs are associated with aging and neurodegenerative disorders. the prevalence of cmbs has not previously been well established. in this study, 445 patients with ms (266 with relapsing-remitting ms, 138 with secondary progressive ms, and 41 with primary progressive ms), 45 patients with cis, 51 patien ... | 2016 | 27308776 |
| diffusion weighted mr imaging of breast and correlation of prognostic factors in breast cancer. | through diffusion weighted imaging (dwi), information related to early molecular changes, changes in the permeability of cell membranes, and early morphologic and physiologic changes such as cell swelling can be obtained. | 2016 | 27308074 |
| pediatric intussusception in northern iran: comparison of recurrent with non-recurrent cases. | intussusception represents as the invagination of a part of the intestine into itself and is the most common cause of intestinal obstruction in infants and children between 6 months to 3-years-old. | 2016 | 27307967 |
| optimal design for informative protocols in xenograft tumor growth inhibition experiments in mice. | tumor growth inhibition (tgi) models are increasingly used during preclinical drug development in oncology for the in vivo evaluation of antitumor effect. tumor sizes are measured in xenografted mice, often only during and shortly after treatment, thus preventing correct identification of some tgi model parameters. our aims were (i) to evaluate the importance of including measurements during tumor regrowth and (ii) to investigate the proportions of mice included in each arm. for these purposes, ... | 2016 | 27306546 |
| q&a: fabulous fact fisher. | 2016 | 27306177 | |
| capacity of very noisy communication channels based on fisher information. | we generalize the asymptotic capacity expression for very noisy communication channels to now include coloured noise. for the practical scenario of a non-optimal receiver, we consider the common case of a correlation receiver. due to the central limit theorem and the cumulative characteristic of a correlation receiver, we model this channel noise as additive gaussian noise. then, the channel capacity proves to be directly related to the fisher information of the noise distribution and the weak s ... | 2016 | 27306041 |
| clinical efficacy of 2-phase versus 4-phase computed tomography for localization in primary hyperparathyroidism. | four-dimensional computed tomography is being used increasingly for localization of abnormal glands in primary hyperparathyroidism. we hypothesized that compared with traditional 4-phase imaging, 2-phase imaging would halve the radiation dose without compromising parathyroid localization and clinical outcomes. | 2016 | 27302106 |
| dicke coupling by feasible local measurements at the superradiant quantum phase transition. | we address characterization of many-body superradiant systems and establish a fundamental connection between quantum criticality and the possibility of locally estimating the coupling constant, i.e., extracting its value by probing only a portion of the whole system. in particular, we consider dicke-like superradiant systems made of an ensemble of two-level atoms interacting with a single-mode radiation field at zero effective temperature, and address estimation of the coupling by measurements p ... | 2016 | 27300841 |
| clinical significance and characteristic clinical differences of cytolytic vaginosis in recurrent vulvovaginitis. | the study aimed to evaluate whether cytolytic vaginosis (cv) has important clinical implications for recurrent vulvovaginitis and to identify clinical differences between cv and vulvovaginal candidosis (vvc). | 2017 | 27300413 |
| second trimester screening of preeclampsia using maternal characteristics and uterine and ophthalmic artery doppler. | purpose: to establish the performance of a multi-parametric test including maternal risk factors and maternal uterine and ophthalmic artery doppler in the second trimester of pregnancy for the prediction of preeclampsia (pe). materials and methods: we performed a prospective observational cohort study with pregnant women who underwent a second trimester morphology scan. maternal uterine and ophthalmic artery doppler examinations were performed in 415 singleton pregnancies between 18 and 23 weeks ... | 2016 | 27300275 |
| low volume polyethylene glycol with ascorbic acid, sodium picosulfate-magnesium citrate, and clear liquid diet alone prior to small bowel capsule endoscopy. | to compare low volume polyethylene glycol with ascorbic acid, sodium picosulfate-magnesium citrate and clear liquid diet alone as bowel preparation prior to small bowel capsule endoscopy (ce). | 2016 | 27298715 |
| comparison of outcome of modified millard's incision and delaire's functional method in primary repair of unilateral cleft lip: a prospective study. | certain preoperative anatomical features may lead the surgeon to choose one particular incision pattern in preference to another. no one technique of cleft lip repair consistently produces ideal aesthetic and functional results. | 2016 | 27298546 |
| misconceptions regarding autogenous tooth transplantations: a survey. | the aim of this cross-sectional study was to assess knowledge regarding autogenous tooth transplantation among oral and maxillofacial surgery (omfs) residents in india. | 2016 | 27298540 |
| a novel locally linear knn method with applications to visual recognition. | a locally linear k nearest neighbor (llk) method is presented in this paper with applications to robust visual recognition. specifically, the concept of an ideal representation is first presented, which improves upon the traditional sparse representation in many ways. the objective function based on a host of criteria for sparsity, locality, and reconstruction is then optimized to derive a novel representation, which is an approximation to the ideal representation. the novel representation is fu ... | 2017 | 27295691 |
| survey on association between mycoplasma hominis endocervical infection and spontaneous abortion using polymerase chain reaction. | mycoplasma infections are suggested as etiology of adverse pregnancy outcomes. | 2016 | 27294216 |
| recurrent diplopia in a pediatric patient with bickerstaff brainstem encephalitis. | introduction. acute complete external ophthalmoplegia is a rare finding in clinical practice that is associated with diseases affecting the neuromuscular junction, the oculomotor nerves, or the brainstem. ophthalmoplegia has been reported with acute ataxia in miller fisher syndrome (mfs) and bickerstaff brainstem encephalitis (bbe). up to 95% of these cases are associated with anti-gq1b antibodies. only a small number of cases of anti-gq1b negative mfs have been documented in pediatric patients. ... | 2016 | 27293928 |
| outcomes and revision rates in normal, overweight, and obese patients 5 years after lumbar fusion. | obesity is a growing problem in health care. studies have demonstrated similar functional outcomes but higher complication rates after spine surgery in obese patients. | 2016 | 27293121 |
| robotic-assisted vs traditional laparoscopic surgery for endometrial cancer: a randomized controlled trial. | previous studies comparing robotic-assisted laparoscopic surgery to traditional laparoscopic or open surgery in gynecologic oncology have been retrospective. to our knowledge, no prospective randomized trials have thus far been performed on endometrial cancer. | 2016 | 27288987 |
| hepatic radiofrequency ablation: markedly reduced systemic effects by modulating periablational inflammation via cyclooxygenase-2 inhibition. | to determine whether celecoxib, a cyclooxygenase-2 (cox-2) inhibitor, can potentiate hepatic radiofrequency ablation (rfa)-induced local cellular infiltration and distant tumour growth. | 2017 | 27287478 |
| surgical management of pediatric vesicoureteral reflux: a comparative study between endoscopic, laparoscopic, and open surgery. | our retrospective study compared the results of three surgical procedures for correction of pediatric vesicoureteral reflux (vur): open cohen, laparoscopic lich-gregoir reimplantation (levur), and endoscopic subureteric injection (sting) procedure. | 2016 | 27284903 |
| differential co-expression analysis of venous thromboembolism based on gene expression profile data. | the aim of the present study was to screen differentially co-expressed genes and the involved transcription factors (tfs) and micrornas (mirnas) in venous thromboembolism (vte). microarray data of gse19151 were downloaded from gene expression omnibus, including 70 patients with vte and 63 healthy controls. principal component analysis (pca) was performed using r software. differential co-expression analysis was performed using r, followed by screening of modules using cytoscape. functional annot ... | 2016 | 27284300 |
| hot melt extrusion as an approach to improve solubility, permeability and oral absorption of a psychoactive natural product, piperine. | the aims of the current research project were to investigate the efficiency of various polymers to enhance the solubility and increase the systemic absorption of piperine using hot melt extrusion technology. | 2016 | 27283755 |
| prediction of residue-residue contact matrix for protein-protein interaction with fisher score features and deep learning. | protein-protein interactions play essential roles in many biological processes. acquiring knowledge of the residue-residue contact information of two interacting proteins is not only helpful in annotating functions for proteins, but also critical for structure-based drug design. the prediction of the protein residue-residue contact matrix of the interfacial regions is challenging. in this work, we introduced deep learning techniques (specifically, stacked autoencoders) to build deep neural netwo ... | 2016 | 27282356 |
| free interval duration: clinical evidence of the primary role of excitement in bipolar disorder. | cyclicity is the essential feature of bipolar disorder, but the effect of different cycle patterns on the clinical features is poorly understood. moreover, no studies investigated the relationship between mania and depression inside the manic-depressive cycle. | 2016 | 27280864 |
| elevated levels of chemerin, leptin, and interleukin-18 in gestational diabetes mellitus. | we aimed to assess the levels of adipokine and their relation to gestational diabetic related clinical phenotypes and fetal growth parameters. | 2017 | 27278709 |
| studies on tissue characterization by texture analysis with co-occurrence matrix method using ultrasonography and ct imaging. | we used texture analysis with the co-occurrence matrix method to analyze ultrasonograms from normal and diseased livers, and x-ray ct images obtained from normal cases and cases of idiopathic interstitial pneumonia. ten cases of normal, fatty, and cirrhotic livers; 10 cases of normal lungs; and 10 cases of idiopathic interstitial pneumonia, all confirmed by clinical findings, laboratory data, surgery, or biopsy, were the subjects of this study. we compared the results of texture analysis in norm ... | 2002 | 27277966 |
| propofol use in pediatric patients with food allergy and eosinophilic esophagitis. | propofol is a safe, well-tolerated anesthetic that is labeled as contraindicated in patients with egg or soy allergy. this contraindication has become increasingly problematic given the rising incidence of food allergy and eosinophilic esophagitis (eoe). to address this issue, we studied practice patterns of propofol use for esophagogastroduodenoscopies in children with eoe and food allergies at our institution. a retrospective observational study of 1365 esophagogastroduodenoscopies from januar ... | 2017 | 27276432 |
| pregnancy intentions and safer pregnancy knowledge among female sex workers in port elizabeth, south africa. | to assess the association between human immunodeficiency virus (hiv) and pregnancy intentions and safer conception knowledge among female sex workers in port elizabeth, south africa. | 2016 | 27275799 |
| the different baryonic tully-fisher relations at low masses. | we compare the baryonic tully-fisher relation (btfr) of simulations and observations of galaxies ranging from dwarfs to spirals, using various measures of rotational velocity vrot. we explore the btfr when measuring vrot at the flat part of the rotation curve, vflat, at the extent of h i gas, vlast, and using 20 per cent (w20) and 50 per cent (w50) of the width of h i line profiles. we also compare with the maximum circular velocity of the parent halo, [formula: see text], within dark matter onl ... | 2016 | 27274704 |
| clinical and radiographic assessment of mineral trioxide aggregate and calcium hydroxide as apexification agents in traumatized young permanent anterior teeth: a comparative study. | to evaluate and compare the efficacy of mineral trioxide aggregate (mta) and traditionally used calcium hydroxide (ca(oh)2) in inducing root end formation of immature roots of traumatized young permanent anterior teeth. | 2017 | 27274351 |
| sirna-induced silencing of hypoxia-inducible factor 3α (hif3α) increases endurance capacity in rats. | molecular mechanisms of adaptation to exercise despite a large number of studies remain unclear. one of the crucial factors in this process is hypoxia inducible factor (hif) that regulates transcription of many target genes encoding proteins that are implicated in molecular adaptation to hypoxia. experiments were conducted on 24 adult male fisher rats. real-time pcr analysis was performed for quantitative evaluation of hif3α, igf1, glut-4 and pdk-1 in m. gastrocnemius, m. soleus, in lung and hea ... | 2016 | 27274101 |
| effects of 14 versus 21 days of nimodipine therapy on neurological outcomes in aneurysmal subarachnoid hemorrhage patients. | oral nimodipine is standard therapy for patients suffering an aneurysmal subarachnoid hemorrhage (asah). during a national drug shortage, nimodipine therapy was shortened from a 21-day course to a 14-day course at our institution. | 2016 | 27273676 |
| experiments with seasonal forecasts of ocean conditions for the northern region of the california current upwelling system. | resource managers at the state, federal, and tribal levels make decisions on a weekly to quarterly basis, and fishers operate on a similar timeframe. to determine the potential of a support tool for these efforts, a seasonal forecast system is experimented with here. jisao's seasonal coastal ocean prediction of the ecosystem (j-scope) features dynamical downscaling of regional ocean conditions in washington and oregon waters using a combination of a high-resolution regional model with biogeochem ... | 2016 | 27273473 |
| retrieval of brain tumors by adaptive spatial pooling and fisher vector representation. | content-based image retrieval (cbir) techniques have currently gained increasing popularity in the medical field because they can use numerous and valuable archived images to support clinical decisions. in this paper, we concentrate on developing a cbir system for retrieving brain tumors in t1-weighted contrast-enhanced mri images. specifically, when the user roughly outlines the tumor region of a query image, brain tumor images in the database of the same pathological type are expected to be re ... | 2016 | 27273091 |
| changes in brain resting-state functional connectivity associated with peripheral nerve block: a pilot study. | limited information exists on the effects of temporary functional deafferentation (tfd) on brain activity after peripheral nerve block (pnb) in healthy humans. increasingly, resting-state functional connectivity (rsfc) is being used to study brain activity and organization. the purpose of this study was to test the hypothesis that tfd through pnb will influence changes in rsfc plasticity in central sensorimotor functional brain networks in healthy human participants. | 2016 | 27272674 |
| ameloblastoma: 25 year experience at a single institution. | ameloblastoma is a rare, locally aggressive odontogenic neoplasm, accounting for fewer than 1 % of head and neck tumors. recent literature suggests that the initial surgical approach and histologic growth patterns are the most important prognostic determinants in ameloblastoma. the aim of this study was to compare the clinical presentation, management, and outcomes of patients with ameloblastoma with data reported in the literature; the study spanned 2 decades at a single institution. the instit ... | 2016 | 27272180 |
| effects of heat acclimation on hand cooling efficacy following exercise in the heat. | this study examined the separate and combined effects of heat acclimation and hand cooling on post-exercise cooling rates following bouts of exercise in the heat. seventeen non-heat acclimated (nha) males (mean ± se; age, 23 ± 1 y; mass, 75.30 ± 2.27 kg; maximal oxygen consumption [vo2 max], 54.1 ± 1.3 ml·kg(-1)·min(-1)) completed 2 heat stress tests (hst) when nha, then 10 days of heat acclimation, then 2 hst once heat acclimated (ha) in an environmental chamber (40°c; 40%rh). hsts were 2 60-mi ... | 2017 | 27268072 |
| pharmacophore modeling, comprehensive 3d-qsar, and binding mode analysis of tgr5 agonists. | takeda g-protein-coupled receptor 5 (tgr5) is emerging as an important and promising target for the development of anti-diabetic drugs. pharmacophore modeling and atom-based 3d-qsar studies were carried out on a new series of 5-phenoxy-1,3-dimethyl-1h-pyrazole-4-carboxamides as highly potent agonists of tgr5. the generated best six featured pharmacophore model aahhrr consists of two hydrogen bond acceptors (a): two hydrophobic groups (h) and two aromatic rings (r). the constructed 3d-qsar model ... | 2017 | 27267434 |
| increased serum concentrations of signal peptide-cub-egf domain-containing protein-1 in patients with aneurysmal subarachnoid hemorrhage. | signal peptide-cub-epidermal growth factor domain-containing protein 1 (scube1), a marker for coagulation, is correlated with prognosis of some critical illnesses. the current study was designed to investigate the potential prognostic value of serum scube1 concentrations in patients with aneurysmal subarachnoid hemorrhage (asah). | 2016 | 27265525 |
| testicular prostheses in children: is earlier better? | the absence of a testis occurs for various reasons in children, but testicular prosthesis implantation in children is uncommon. the optimal time for prosthesis placement is still unclear, and its complication rate has been poorly studied in children. | 2016 | 27264050 |
| partial ileal bypass affords protection from onset of type 2 diabetes. | partial ileal bypass (pib) in the national institutes of health-sponsored program on the surgical control of the hyperlipidemias (posch) randomized controlled trial was found to reduce plasma cholesterol, in particular low density lipoprotein cholesterol, with concomitant retardation of atherosclerotic cardiovascular disease and increased life expectancy. glucagon-like peptide-1, related to amelioration of type 2 diabetes, is increased over 5-fold after pib. we hypothesized that pib, in addition ... | 2017 | 27262236 |
| a detailed analysis of mandibular angle fractures: epidemiology, patterns, treatments, and outcomes. | the purpose was to analyze mandibular angle fractures by examining epidemiologic trends and mechanisms of injury and to determine whether a statistically meaningful relation existed between certain treatment modalities and patient outcomes. | 2016 | 27262184 |
| therapeutic drug monitoring, electronic health records, and pharmacokinetic modeling to evaluate sirolimus drug exposure-response relationships in renal transplant patients. | sirolimus, an immunosuppressive agent used in renal transplantation, can prevent allograft rejection. identification of the therapeutic index (the ratio of minimum toxic concentration to minimum therapeutic concentration) for immunosuppresants is necessary to optimize the care of patients and set standards for bioequivalence evaluation of sirolimus products. however, the therapeutic index for sirolimus has been inconsistently defined, potentially because of inconsistencies in sirolimus exposure- ... | 2016 | 27259059 |
| automation of classical qeeg trending methods for early detection of delayed cerebral ischemia: more work to do. | the purpose of this study is to evaluate automated implementations of continuous eeg monitoring-based detection of delayed cerebral ischemia based on methods used in classical retrospective studies. we studied 95 patients with either fisher 3 or hunt hess 4 to 5 aneurysmal subarachnoid hemorrhage who were admitted to the neurosciences icu and underwent continuous eeg monitoring. we implemented several variations of two classical algorithms for automated detection of delayed cerebral ischemia bas ... | 2016 | 27258446 |
| clinical development and implementation of an institutional guideline for prospective eeg monitoring and reporting of delayed cerebral ischemia. | delayed cerebral ischemia (dci) is the most common and disabling complication among patients admitted to the hospital for subarachnoid hemorrhage (sah). clinical and radiographic methods often fail to detect dci early enough to avert irreversible injury. we assessed the clinical feasibility of implementing a continuous eeg (ceeg) ischemia monitoring service for early dci detection as part of an institutional guideline. an institutional neuromonitoring guideline was designed by an interdisciplina ... | 2016 | 27258445 |
| effects of microwave ablation on arterial and venous vasculature after treatment of hepatocellular carcinoma. | purpose to characterize vessel occlusion rates and their role in local tumor progression in patients with hepatocellular carcinoma (hcc) who underwent microwave tumor ablation. materials and methods this institutional review board approved, hipaa-compliant retrospective review included 95 patients (75 men and 20 women) with 124 primary hccs who were treated at a single center between january 2011 and march 2014. complete occlusion of the portal veins, hepatic veins, and hepatic arteries within a ... | 2016 | 27257951 |
| feature selection of fmri data based on normalized mutual information and fisher discriminant ratio. | pattern classification has been increasingly used in functional magnetic resonance imaging (fmri) data analysis. however, the classification performance is restricted by the high dimensional property and noises of the fmri data. in this paper, a new feature selection method (named as "nmi-f") was proposed by sequentially combining the normalized mutual information (nmi) and fisher discriminant ratio. in nmi-f, the normalized mutual information was firstly used to evaluate the relationships betwe ... | 2016 | 27257882 |
| recurrent microdeletions at xq27.3-xq28 and male infertility: a study in the czech population. | genetic causes of male infertility are hypothesized to involve multiple types of mutations, from single gene defects to complex chromosome rearrangements. recently, several recurrent x-chromosome microdeletions (located in subtelomeric region of the long arm) were reported to be associated with male infertility in spanish and italian males. the aim of our study was to test their prevalence and infertility association in population of men from the czech republic. | 2016 | 27257673 |
| flt-pet/ct diagnosis of primary and metastatic nodal lesions of gastric cancer: comparison with fdg-pet/ct. | to examine the diagnostic performance of (18)f-fluorothymidine (flt)-pet/ct of primary and metastatic nodal lesions of gastric cancer by comparing with (18)f-fluorodeoxyglucose (fdg)-pet/ct. | 2016 | 27255652 |
| the predictive validity of the national board of osteopathic medical examiners' comlex-usa examinations with regard to outcomes on american board of family medicine examinations. | to examine the predictive validity of the national board of osteopathic medical examiners' comprehensive osteopathic medical licensing examination of the united states of america (comlex-usa) series with regard to the american board of family medicine's (abfm's) in-training examination (ite) and maintenance of certification for family physicians (mc-fp) examination. | 2016 | 27254014 |
| kir2dl2 and kir2ds2 as genetic markers to the methotrexate response in rheumatoid arthritis patients. | disease modifying anti-rheumatic drugs (dmards) are aimed to interfere with rheumatoid arthritis (ra) progression and reduce the joint damage; however, not all patients respond alike. killer-cell immunoglobulin-like receptors (kir) and their ligands, human leucocyte antigen class i (hla-i), have been associated with ra pathology; therefore, kir and hla genes may influence the treatment response. | 2016 | 27251940 |
| optimizing flip angles for metabolic rate estimation in hyperpolarized carbon-13 mri. | hyperpolarized carbon-13 magnetic resonance imaging has enabled the real-time observation of perfusion and metabolism in vivo. these experiments typically aim to distinguish between healthy and diseased tissues based on the rate at which they metabolize an injected substrate. however, existing approaches to optimizing flip angle sequences for these experiments have focused on indirect metrics of the reliability of metabolic rate estimates, such as signal variation and signal-to-noise ratio. in t ... | 2016 | 27249825 |
| presence of the panton-valentine leukocidin genes in methicillin-resistant staphylococcus aureus is associated with severity and clinical outcome of hospital-acquired pneumonia in a single center study in china. | the panton-valentine leukocidin (pvl) genes of methicillin-resistant staphylococcus aureus (mrsa) have previously been associated with severe infections. here, the impact of the pvl genes on severity of disease and clinical outcome of patients with hospital-acquired pneumonia (hap) or ventilator-associated pneumonia (vap) due to mrsa was investigated in a single center observational study in a hospital in china. hap due to mrsa was diagnosed in 100 patients and 13 of the patients were pvl positi ... | 2016 | 27249225 |
| unilateral ultrasound-guided transversus abdominis plane block after nephrectomy; postoperative pain and use of opioids. | pain has a wide spectrum of effects on the body and inadequately controlled postoperative pain may have harmful physiologic and psychological consequences and increase morbidity. in addition, opioid anesthetic agents in high doses can blunt endocrine and metabolic responses following surgery and are associated with side effects including dizziness, nausea, vomiting, constipation, and respiratory depression. | 2016 | 27247931 |
| correlating the sonographic finding of echogenic debris in the bladder lumen with urinalysis. | the purpose of this study was to determine the significance of urinary bladder debris detected by sonography. | 2016 | 27246660 |
| testosterone and trenbolone enanthate increase mature myostatin protein expression despite increasing skeletal muscle hypertrophy and satellite cell number in rodent muscle. | the androgen-induced alterations in adult rodent skeletal muscle fibre cross-sectional area (fcsa), satellite cell content and myostatin (mstn) were examined in 10-month-old fisher 344 rats (n = 41) assigned to sham surgery, orchiectomy (orx), orx + testosterone (test; 7.0 mg week(-1) ) or orx + trenbolone (tren; 1.0 mg week(-1) ). after 29 days, animals were euthanised and the levator ani/bulbocavernosus (labc) muscle complex was harvested for analyses. labc muscle fcsa was 102% and 94% higher ... | 2017 | 27246614 |
| effect of non-invasive oxygenation strategies in immunocompromised patients with severe acute respiratory failure: a post-hoc analysis of a randomised trial. | the use of non-invasive ventilation is controversial in immunocompromised patients with acute respiratory failure, whereas the use of high-flow nasal cannula oxygen therapy is growing as an alternative to standard oxygen. we aimed to compare outcomes of immunocompromised patients with acute respiratory failure treated with standard oxygen with those treated with high-flow nasal cannula oxygen alone or high-flow nasal cannula oxygen associated with non-invasive ventilation. | 2016 | 27245914 |
| fishers' knowledge on the coast of brazil. | although fishers' knowledge has been recently considered into management programmes, there is still the need to establish a better understanding of fishers' perceptions and cognition. fishers can provide novel information on the biology and ecology of species, which can potentially be used in the management of fisheries. the knowledge fishers have and how they classify nature is empirically based. it is common, for example, to observe that fishers' taxonomy is often represented by the generic le ... | 2016 | 27245047 |
| increased incidence of fbxw7 and pole proofreading domain mutations in young adult colorectal cancers. | the incidence and outcomes of patients with colorectal cancer (crc) varies by age. younger patients tend to have sporadic cancers that are not detected by screening and worse survival. to understand whether genetic differences exist between age cohorts, the authors sought to characterize unique genetic alterations in patients with crc. | 2016 | 27244218 |
| disruption of splenic lymphoid tissue and plasmacytosis in canine visceral leishmaniasis: changes in homing and survival of plasma cells. | visceral leishmaniasis (vl) is a disease caused by leishmania infantum, which is transmitted by phlebotomine sandflies. dogs are the main urban reservoir of this parasite and the disease presents similar characteristics in both humans and dogs. in this paper, we investigated the potential pathways involved in plasma cell replacement of normal cell populations in the spleen, with respect to disease severity in dogs from an endemic area for visceral leishmaniasis. to this end, canine spleen sample ... | 2016 | 27243459 |
| see-and-treat for high-grade cytology: do young women have different rates of high-grade histology? | to compare rates of cervical intraepithelial neoplasia grade 3 or greater (cin3+) between women aged 21 to 24 and women aged 25 or older undergoing a see-and-treat strategy for high-grade squamous intraepithelial lesion (hsil) cytology. | 2016 | 27243140 |
| characterization of spinal cord lesions in cattle and horses with rabies: the importance of correct sampling. | twenty-six cattle and 7 horses were diagnosed with rabies. samples of brain and spinal cord were processed for hematoxylin and eosin staining and immunohistochemistry (ihc). in addition, refrigerated fragments of brain and spinal cord were tested by direct fluorescent antibody test and intracerebral inoculation in mice. statistical analyses and fisher exact test were performed by commercial software. histologic lesions were observed in the spinal cord in all of the cattle and horses. inflammator ... | 2016 | 27240569 |
| is the tunnel technique more effective than open augmentation with a titanium-reinforced polytetrafluoroethylene membrane for horizontal ridge augmentation? | studies have shown that horizontal ridge augmentation with a nonresorbable membrane is subject to a relatively frequent occurrence of dehiscence and loss of the graft. this study was designed to compare the outcomes of a tunnel technique versus an open technique using a titanium-reinforced polytetrafluoroethylene (ptfe) membrane. | 2016 | 27240025 |
| complement factor h and loc387715/arms2/htra1 variant's frequencies and phenotypic associations in neovascular age-related macular degeneration, a pilot study. | to evaluate the frequency of 12 single nucleotide polymorphisms (snps) of complement factor h (cfh) and loc387715/arms2/hrta1 and their association with some of the presenting clinical features of neovascular age-related macular degeneration (amd). | 2016 | 27239600 |
| miller-fisher syndrome: are anti-gad antibodies implicated in its pathophysiology? | miller-fisher syndrome (mfs) is considered as a variant of the guillain-barre syndrome (gbs) and its characteristic clinical features are ophthalmoplegia, ataxia, and areflexia. typically, it is associated with anti-gq1b antibodies; however, a significant percentage (>10%) of these patients are seronegative. here, we report a 67-year-old female patient who presented with the typical clinical features of mfs. workup revealed antibodies against glutamic acid decarboxylase (gad) in relatively high ... | 2016 | 27239355 |
| efficacy of peroral endoscopic myotomy vs other achalasia treatments in improving esophageal function. | to assess and compare the esophageal function after peroral endoscopic myotomy (poem) vs other conventional treatments in achalasia. | 2016 | 27239118 |
| [in process citation]. | introducción: la desnutrición relacionada con la enfermedad (dre) es un problema sociosanitario frecuente que afecta preferentemente a los mayores de 65 años, que aumenta la morbimortalidad y disminuye la calidad de vida. objetivo: estudiar la prevalencia de dre en mayores de 65 años en diferentes centros sociosanitarios del servicio regional de bienestar social de la comunidad de madrid. métodos: estudio transversal en 33 centros sociosanitarios de madrid (6 centros de atención primaria [ap], ... | 2016 | 27238783 |
| development of medians generators for the calculation of mom for the first-trimester down syndrome maternal serum markers. | the down syndrome risk calculation software, fast screen pre i plus, from thermo fisher scientific, converts the first-trimester maternal serum markers concentrations (papp-a and hcgβ) into degrees of extreme (doe). to meet the requirements of the french legislation as well as those of the certified biologists for down syndrome screening, a conversion tool for doe into multiple of the median (mom), intermediate reference value for the screening, was developed. in absence of any median polynomial ... | 2016 | 27237803 |
| gene polymorphisms of cd207 (langerin) are associated with end-stage renal disease. | the cd207 molecule, also known as langerin, is known to be the first immunologic barrier expressed on langerhans cells, which are the immature dendritic cells of the epidermis and mucosa. inflammation could be a causal factor in the progression of chronic kidney disease. to date, convincing experimental and clinical evidence indicates that langerin plays a role in antigen uptake and processing, which is the primary function of langerhans cells. in this study, we hypothesized that polymorphisms o ... | 2016 | 27234728 |
| ligand release pathways obtained with wexplore: residence times and mechanisms. | the binding of ligands with their molecular receptors is of tremendous importance in biology. although much emphasis has been placed on characterizing binding sites and bound poses that determine the binding thermodynamics, the pathway by which a ligand binds importantly determines the binding kinetics. the computational study of entire unbiased ligand binding and release pathways is still an emerging field, made possible only recently by advances in computational hardware and sampling methodolo ... | 2016 | 27231969 |
| sequential transarterial embolization followed by percutaneous vertebroplasty is safe and effective in pain management in vertebral metastases. | vertebral metastases are the most frequent vertebral tumor. transarterial embolization (tae) devascularizes the tumor, resulting in tumor necrosis. percutaneous vertebroplasty (pvp), a minimally invasive procedure, can effectively relieve tumor-related pain and improve spine stability. unfortunately, the pvp technique is of limited use in controlling the progression of vertebral tumor, especially for paravertebral metastases. tae combined with pvp may achieve a better control on vertebral metast ... | 2016 | 27228522 |
| association between head tilt and asymmetric epiblepharon. | epiblepharon is known to be bilateral and symmetric. however, asymmetric epiblepharon is frequently observed in patients with head tilt and, to date, this condition has not been investigated. | 2016 | 27228208 |
| spectrum of opportunistic infections and risk factors for in-hospital mortality of admitted aids patients in shanghai. | to investigate the frequency and the spectrum of major opportunistic infections (ois), evaluate the major clinical factors associated with each specific oi, and identify the risk factors for in-hospital death among hiv patients in east china.a retrospective cohort study was made including all the hiv-infected patients who were admitted for the first time to the shanghai public health clinical center during june 1, 2013 to june 1, 2015. the demographic and clinical data were collected. comparison ... | 2016 | 27227959 |
| effects of obstetric complications on adolescent postpartum contraception and rapid repeat pregnancy. | to determine whether complications during pregnancy or at delivery influence postpartum contraception choices and rapid repeat pregnancy rates in adolescent women. design, setting, participants, interventions, and main outcome measures: this retrospective cohort study included 321 adolescents delivering at umass memorial healthcare. complications during pregnancy and delivery along with subsequent contraception use were investigated. postpartum contraception choice (long-acting reversible contra ... | 2016 | 27222491 |
| association of obesity and severity of acute asthma exacerbations in filipino children. | increased body mass index (bmi) may be a risk factor for the development and severity of asthma. however, the effect of obesity on asthma exacerbations is unclear. | 2016 | 27221063 |
| evaluation of elbow flexion following free muscle transfer from the medial gastrocnemius or transfer from the latissimus dorsi, in cases of traumatic injury of the brachial plexus. | to compare the gain in elbow flexion in patients with traumatic injury of the brachial plexus following muscle transfer from latissimus dorsi with the gain following free muscle transfer from the medial belly of the gastrocnemius. | 2017 | 27218077 |
| social networks and environmental outcomes. | social networks can profoundly affect human behavior, which is the primary force driving environmental change. however, empirical evidence linking microlevel social interactions to large-scale environmental outcomes has remained scarce. here, we leverage comprehensive data on information-sharing networks among large-scale commercial tuna fishers to examine how social networks relate to shark bycatch, a global environmental issue. we demonstrate that the tendency for fishers to primarily share in ... | 2016 | 27217551 |
| classification of biodiesel and fuel blends using gas chromatography - differential mobility spectrometry with cluster analysis and isolation of c18:3 me by dual ion filtering. | fatty acid alkyl esters (faaes) were determined at 10-100mg/l in biodiesel and blends with petrodiesel without sample pre-treatment using gas chromatography with a tandem differential mobility detector. selectivity was provided through chromatographic separations and atmospheric pressure chemical ionization reactions in the detector with mobility characterization of gas ions. limits of detection were ~0.5ng with an average of 2.98% rsd for peak area precision, ≤1.3% rsd for retention time precis ... | 2016 | 27216685 |
| [prognostic value of preoperative neutrophil-to-lymphocyte ratio in the elderly patients over 75 years old with gastric cancer]. | to investigate the clinical implication of preoperative neutrophil-to-lymphocyte ratio (nlr), and association of nlr with the prognosis of the elderly patients over 75 years old with primary gastric cancer. | 2016 | 27215519 |
| an efficient genome-wide association test for mixed binary and continuous phenotypes with applications to substance abuse research. | we propose a new genome-wide association test for mixed binary and continuous phenotypes that uses an efficient numerical method to estimate the empirical distribution of the fisher's combination statistic under the null hypothesis. our simulation study shows that the proposed method controls the type i error rate and also maintains its power at the level of the permutation method. more importantly, the computational efficiency of the proposed method is much higher than the one of the permutatio ... | 2016 | 27215414 |
| assessing cumulative impacts of forest development on the distribution of furbearers using expert-based habitat modeling. | cumulative impacts of anthropogenic landscape change must be considered when managing and conserving wildlife habitat. across the central-interior of british columbia, canada, industrial activities are altering the habitat of furbearer species. this region has witnessed unprecedented levels of anthropogenic landscape change following rapid development in a number of resource sectors, particularly forestry. our objective was to create expert-based habitat models for three furbearer species: fishe ... | 2016 | 27209791 |
| international medical graduates in radiation oncology: historical trends and comparison with other medical specialties. | this is the first national resident matching program analysis evaluating historical patterns of international medical graduates (imgs) in radiation oncology (ro) and providing comparison with american (md) medical graduates (amgs), osteopathic students (dos), unfilled positions, and other specialties. | 2016 | 27209507 |
| demyelinating guillain-barré syndrome recurs more frequently than axonal subtypes. | guillain-barré syndrome (gbs) is considered a monophasic disorder yet recurrences occur in up to 6% of patients. we retrospectively studied an italian-japanese population of 236 gbs and 73 miller fisher syndrome (mfs) patients and searched for factors which may be associated with recurrence. a recurrent patient was defined as having at least two episodes that fulfilled the diagnostic criteria for gbs and mfs with an identifiable recovery after each episode and a minimum of 2months between episod ... | 2016 | 27206890 |
| perioperative risks of untreated obstructive sleep apnea in the bariatric surgery patient: a retrospective study. | the use of continuous positive airway pressure (cpap) perioperatively in bariatric surgery patients with obstructive sleep apnea (osa) has been controversial. although studies have demonstrated that cpap use is safe in bariatric patients, prior studies have not shown improvement in outcomes in these patients. | 2016 | 27206775 |
| guillain-barré syndrome following the 2009 pandemic monovalent and seasonal trivalent influenza vaccination campaigns in spain from 2009 to 2011: outcomes from active surveillance by a neurologist network, and records from a country-wide hospital discharge database. | studies have shown a slight excess risk in guillain-barré syndrome (gbs) incidence associated with a(h1n1)pdm09 vaccination campaign and seasonal trivalent influenza vaccine immunisations in 2009-2010. we aimed to assess the incidence of gbs as a potential adverse effect of a(h1n1)pdm09 vaccination. | 2016 | 27206524 |
| correction: measuring fisher information accurately in correlated neural populations. | [this corrects the article doi: 10.1371/journal.pcbi.1004218.]. | 2016 | 27203712 |
| fisher-symmetric informationally complete measurements for pure states. | we introduce a new kind of quantum measurement that is defined to be symmetric in the sense of uniform fisher information across a set of parameters that uniquely represent pure quantum states in the neighborhood of a fiducial pure state. the measurement is locally informationally complete-i.e., it uniquely determines these parameters, as opposed to distinguishing two arbitrary quantum states-and it is maximal in the sense of a multiparameter quantum cramér-rao bound. for a d-dimensional quantum ... | 2016 | 27203310 |
| effects of a combined exercise program using an ipad for older adults. | the purpose of this study was to examine the function, health status, and efficacy effects of a combined exercise program using an ipad among older women in korea, a tech-savvy country. | 2016 | 27200215 |
| valid statistical inference methods for a case-control study with missing data. | the main objective of this paper is to derive the valid sampling distribution of the observed counts in a case-control study with missing data under the assumption of missing at random by employing the conditional sampling method and the mechanism augmentation method. the proposed sampling distribution, called the case-control sampling distribution, can be used to calculate the standard errors of the maximum likelihood estimates of parameters via the fisher information matrix and to generate ind ... | 2016 | 27199234 |
| risk factors for esophageal fistula associated with chemoradiotherapy for locally advanced unresectable esophageal cancer: a supplementary analysis of jcog0303. | esophageal fistula is a critical adverse event in patients treated with chemoradiotherapy (crt) for locally advanced esophageal cancer. however, risk factors associated with esophageal fistula formation in patients receiving crt have not yet been elucidated.we retrospectively analyzed data obtained from 140 patients who were enrolled in a phase ii/iii trial comparing low-dose cisplatin with standard-dose cisplatin administered in combination with 5-flurouracil and concomitant radiotherapy. inclu ... | 2016 | 27196482 |
| more than anecdotes: fishers' ecological knowledge can fill gaps for ecosystem modeling. | ecosystem modeling applied to fisheries remains hampered by a lack of local information. fishers' knowledge could fill this gap, improving participation in and the management of fisheries. | 2016 | 27196131 |
| oil exploitation and its socioeconomic effects on the niger delta region of nigeria. | the oil exploration and exploitation industry which is majorly centred in the niger delta region is without doubt currently the most important earner of foreign exchange to the nigerian economy. the niger delta is home to an extraordinary variety of people; mostly fishers and farmers with a history of rich cultural heritage. however, the region is suffering from devastating oil pollution. although the effects of oil spill depend on factors such as size or area of spill and geographical location, ... | 2016 | 27194013 |
| slow induction of brain death leads to decreased renal function and increased hepatic apoptosis in rats. | donor brain death (bd) is an independent risk factor for graft survival in recipients. while in some patients bd results from a fast increase in intracranial pressure, usually associated with trauma, in others, intracranial pressure increases more slowly. the speed of intracranial pressure increase may be a possible risk factor for renal and hepatic graft dysfunction. this study aims to assess the effect of speed of bd induction on renal and hepatic injury markers. | 2016 | 27193126 |
| emergent non-image-guided resuscitative endovascular balloon occlusion of the aorta (reboa) catheter placement: a cadaver-based study. | emergent resuscitative endovascular balloon occlusion of the aorta (reboa) insertion for critically injured patients in hemorrhagic shock is performed blindly with fluoroscopic imaging confirmation. the aim of this study was to determine a reliable method for initial reboa catheter insertion with balloon deployment between the left subclavian artery takeoff and the celiac trunk (ct). | 2016 | 27192466 |
| patterns of coral-reef finfish species disappearances inferred from fishers' knowledge in global epicentre of marine shorefish diversity. | in the philippines, very high fishing pressure coincides with the globally greatest number of shorefish species, yet no long-term fisheries data are available to explore species-level changes that may have occurred widely in the most species rich and vulnerable marine ecosystem, namely coral reefs. through 2655 face-to-face interviews conducted between august 2012 and july 2014, we used fishers' recall of past catch rates of reef-associated finfish to infer species disappearances from catches in ... | 2016 | 27191602 |