Publications
Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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the morphology of human immunodeficiency virus (hiv) by negative staining. | we have examined preparations of human immunodeficiency virus 1 (hiv-1) and hiv-2 by negative staining electron microscopy. hiv-2 cultures contained large numbers of 130-200 nm particles containing a 130-nm-long by 30-70 nm-wide core. this core is probably of conical or pear-shaped morphology. some particles exhibited a short fringe that could be seen to comprise a regular arrangement of repeating subunits when visualised end on. identical particles were found in hiv-1 cultures but in much lower ... | 1988 | 3171554 |
localization of the rat immunoglobulin lambda light chain locus to chromosome 11. | previous experiments using rat/mouse somatic cell hybrids have localized the rat c-myc gene to chromosome 7 (sümegi et al. 1983), the rat immunoglobulin kappa locus to chromosome 4 (perlmann et al. 1985), and the rat immunoglobulin heavy chain locus to chromosome 6 (pear et al. 1986). using a similar approach, we now report the localization of the rat immunoglobulin lambda light chain locus to chromosome 11. | 1988 | 3137157 |
6;7 chromosomal translocation in spontaneously arising rat immunocytomas: evidence for c-myc breakpoint clustering and correlation between isotypic expression and the c-myc target. | our previous studies have shown that spontaneously arising immunocytomas in the lou/ws1 strain of rats contain a t(6;7) chromosomal translocation in all seven tumors studied (f. m. babonits, j. spira, g. klein, and h. bazin, int. j. cancer 29:431-437, 1982). we have also shown that the c-myc is located on chromosome 7 (j. sümegi, j. spira, h. bazin, j. szpirer, g. levan, and g. klein, nature (london) 306:497-499, 1983) and the immunoglobulin h cluster on chromosome 6 (w.s. pear, g. wahlström, j. ... | 1988 | 3122026 |
purification and characterization of the inducible a agglutinin of saccharomyces cerevisiae. | a cell surface glycoprotein induced by the mating pheromone alpha factor in saccharomyces cerevisiae a cells has been purified to homogeneity. at 4 x 10(-9) m it strongly inhibits mating-type-specific agglutination between a and alpha cells. the protein is solely o-glycosylated. it consists of 29% carbohydrate and its apparent molecular mass is 22 kd on sds gels. after hf treatment it behaves like a protein of 13 kd; therefore its true molecular mass probably is close to 18 kd. mild periodate tr ... | 1988 | 3044782 |
ultrasonic imaging of equine ovarian follicles and corpora lutea. | one of the most profound theriogenology applications of transrectal diagnostic ultrasonography in mares involves the imaging of ovarian follicles and corpora lutea. the resolving capabilities (frequency) and quality of the scanner directly affect the minimal size of a structure that can be imaged and the quality of the image. high-frequency scanners (5 or 7.5 mhz) of good quality can image a 2-mm follicle and the corpus luteum throughout its functional life. a low-frequency scanner (3 or 3.5 mhz ... | 1988 | 3044535 |
freeze-fracture replica studies of effects of acth treatment and hypophysectomy on the cell surface of the rat adrenal inner cortex. | the morphological change of the cell surface in the inner zone of the adrenal cortex was studied in intact, hypophysectomized, and acth-treated hypophysectomized rats, using freeze-fracture replicas. in both intact and hypophysectomized acth-treated animals, the p fracture face of the plasma membranes of the cortical cells facing capillaries shows groups of characteristic finger-shaped microvilli, which arise horizontally from the edges of a small cavity on the cell surface to form various confi ... | 1987 | 3031917 |
occurrence of lipofuscin pigment granules and "dense microspheres" in the spinal cord of young cats treated with beta,beta'-iminodipropionitrile (idpn). | spinal cords of cats treated with the neurotoxic compound beta,beta'-iminodipropionitrile (idpn) were observed to contain rounded homogeneous bodies, 1-12 microns in diameter, termed "dense microspheres" (dms). these bodies, absent in control animals, were consistently found only in the ventral horns. no relationship with blood vessels was evident. when stained with pas and a modified von kossa's silver nitrate technique, dms remained negative, showing only very slight metachromasia in some tolu ... | 1988 | 2980224 |
three-dimensional reconstruction of negatively stained crystals of the ca2+-atpase from muscle sarcoplasmic reticulum. | the structure of the ca2+ transport atpase from rabbit skeletal muscle sarcoplasmic reticulum has been determined to 25 a resolution by three-dimensional image reconstruction of crystalline membrane tubules induced through exposure to na3vo4 and preserved for electron microscopy in negative stain. the crystalline arrays have projection symmetry p2 and consist of chains of ca2+-atpase dimers arranged in a right-handed helix. the density map shows protein features that project from the membrane su ... | 1986 | 2939255 |
crystallization of the ca2+-atpase of sarcoplasmic reticulum by calcium and lanthanide ions. | two-dimensional crystalline arrays of ca2+-atpase molecules develop in sarcoplasmic reticulum vesicles exposed to ca2+ or lanthanide ions. the ca2+- or lanthanide-induced crystals are presumed to represent the e1 conformation of the ca2+-atpase, and their crystal form is clearly different from the earlier described e2 crystals induced by na3vo4 in the presence of ethylene glycol bis(beta aminoethyl ether)-n,n,n',n'-tetraacetic acid (taylor, k. a., dux, l., and martonosi, a. (1984) j. mol. biol. ... | 1985 | 2931429 |
ultrastructural biology of leishmania (viannia) panamensis (=leishmania braziliensis panamensis) in lutzomyia gomezi (diptera: psychodidae): a natural host-parasite association. | the development of leishmania (viannia) panamensis in a natural sand fly host, lutzomyia gomezi, was studied by light and transmission electron microscopy. new aspects of peripylarian parasite behavior and morphology in the sand fly gut, early bloodmeal stages, and ultrastructural development in the anterior gut were documented. eight distinct morphological forms were observed in the life cycle of the parasite within the insect. in the bloodmeal, amastigotes (1) transformed into stumpy promastig ... | 1989 | 2916730 |
tyrosine hydroxylase immunohistochemistry fails to demonstrate dopaminergic interplexiform cells in the turtle retina. | a number of catecholaminergic, presumably dopaminergic, cells could be observed in the turtle retina, because of their tyrosine hydroxylase immunoreactivity. they were amacrine cells with a pear-shaped soma and dendrites distributed in 3 sublayers within the inner plexiform layer. neither sclerally directed th-positive processes nor terminals in the outer plexiform layer were observed, suggesting that dopaminergic interplexiform cells do not exist in the turtle retina. | 1985 | 2862955 |
chronic disease in goats orally infected with two isolates of the caprine arthritis-encephalitis lentivirus. | newborn saanen goats were orally infected with two distinct biologically cloned isolates of the caprine arthritis-encephalitis lentivirus (caev), designated caev(63) (crawford tb, adams ds, cheevers wp, cork lc: science 207:997, 1980) and caev (co) (cork lc, hadlow wj, crawford tb, gorham jr, piper rc: j infect dis 129:134, 1974; narayan o, clements je, strandberg jd, cork lc, griffin de: j gen virol 50:69, 1980). all infected goats seroconverted for antibodies to caev, and there were no serolog ... | 1988 | 2835548 |
ultrastructural development of leishmania chagasi in its vector, lutzomyia longipalpis (diptera: psychodidae). | the development of leishmania chagasi, etiologic agent of american visceral leishmaniasis, was studied by light and electron microscopy in the gut of the sand fly, lutzomyia longipalpis, a natural vector. new aspects of suprapylarian leishmania behavior were elucidated. in the sand fly midgut, amastigotes transformed into promastigotes (division promastigote i) during a first division sequence within the bloodmeal. secondary division of these promastigotes resulted in a second form (division pro ... | 1989 | 2802019 |
monospermy and polyspermy after partial zona dissection of reinseminated human oocytes. | partial zona dissection (pzd), a zona drilling method that uses mechanical force to open the zona pellucida while the oocyte is shrunken in a sucrose solution, was applied to 121 unfertilized 1-day-old mature human oocytes prior to reinsemination. the 115 surviving oocytes were divided into three groups in which the duration between sucrose addition and reinsemination was varied: i) less than 20 minutes, ii) 21 to 45 minutes, and iii) longer than 45 minutes. there was a trend toward a reduced fe ... | 1989 | 2777173 |
[rhinitis and osmylogenic asthma caused by prickly pear. presentation of a clinical case]. | 2009 | 2749130 | |
[successful treatment of a cheilothorax in lymphangiomatosis of the ribs (gorham-stout syndrome)]. | in 1955 gorham and stout described the syndrome of lymphangiomatosis of the bone resulting in widespread monofocal osteolysis in the skeletal system. the results of therapy are difficult to evaluate as the disease may come to a sudden stand-still. if angiomatosis arises near the thorax, pleural effusion occurs due to simultaneous involution of the thoracic duct. this complication has a fatal outcome and effective treatment is required. a case is reported in a 61-year-old male in whom radiotherap ... | 1989 | 2740881 |
[detection of fruit juice adulteration in apple and pear juice]. | a method has been developed to detect the adulteration of pear juice with apples and apple juice with pears. in different varieties of apples and pears and in several commercial juices the flavonoids were examined by hplc with respect to their quality and quantity. the chalcones phloretin glucoside and phloretin xyloglucoside are typical compounds found in apples (detection limit 7 ng). they are suitable indicators for detecting adulteration of pear juice with apples. isohamnetin glucoside canno ... | 2008 | 2718633 |
intrauterine diagnosis of short-limbed dwarfism. | ten short-limbed fetuses caused by skeletal dysplasia were diagnosed prenatally from september 1984 through july 1988. the final diagnosis was thanatophoric dwarfism in 7 cases and osteogenesis imperfecta congenita in 3 cases. the diagnosis was based on sonographic findings in all cases and postnatal radiography was performed in 3 cases for further confirmation. sonographic examinations revealed markedly shortened limbs and other associated abnormalities, including abnormal skull appearance, pea ... | 2009 | 2699492 |
organization of ribosomal rna genes in alternaria alternata japanese pear pathotype, a host-selective ak-toxin-producing fungus. | dna encoding ribosomal rna (rrna) of alternaria alternata japanese pear pathotype has been cloned in lambda replacement vector, lambda fix. restriction endonuclease mapping and southern hybridization with the 18s and 28s rrnas of saccharomyces cerevisiae revealed the a. alternata rdna to be tandemly repeating 8.15-kilobase pair unit. the restriction fragments of the unit were then subcloned in the plasmid vector bluescribe m13- and partially sequenced. the determined sequences were compared with ... | 1989 | 2697467 |
[prickly pear as an acid absorber]. | 2008 | 2631173 | |
open assessment of the safety and efficacy of thioridazine in the treatment of patients with borderline personality disorder. | a 12-week open study was conducted to assess the possible efficacy and safety of low-dose thioridazine in 11 outpatients (8 women, 3 men) with borderline personality disorder (bpd) diagnosed according to dsm-iii-r (american psychiatric association 1987) and the diagnostic interview for borderline patients (dib; gunderson et al. 1981) criteria. mean thioridazine dose averaged 92 mg per day across the duration of this study. at endpoint, there was a significant reduction in brief psychiatric ratin ... | 1989 | 2631134 |
a case of calcitonin-producing parathyroid adenoma with primary hyperparathyroidism. | a 57-year-old female was admitted to our hospital with general lassitude, loss of appetite, nausea, upper abdominal pain, thirst, polydipsia and polyuria. on admission, she had an asymmetrical pear-shaped tumor in the right supraclavicular region and severe hypercalcemia. plasma c-pth was elevated to 22.72ng/ml. plasma calcitonin was also elevated to 336 pg/ml. she died of respiratory and cardiac failure of two weeks after admission without any positive response to the treatment, including hemod ... | 1989 | 2585894 |
distribution of somatostatin and glucagon immunoreactive cells in the gastric mucosa of some cartilaginous fishes. | the comparative distribution of somatostatin- and glucagon-like-containing cells in the histomorphologically different gastric mucosae of the cartilaginous fishes heptranchias perlo, raja asterias, scyliorhinus canicula, squatina aculeata, and torpedo marmorata was immunocytochemically studied to demonstrate a possible interrelationship between these endocrine cells and/or other endocrine or nonendocrine cells. in the gastric mucosa, these open-type glucagon and somatostatin immunoreactive cells ... | 1989 | 2570006 |
systemic beta-adrenoceptor responses to salbutamol given by metered-dose inhaler alone and with pear shaped spacer attachment: comparison of electrocardiographic, hypokalaemic and haemodynamic effects. | 1. seven normal subjects were given cumulative doubling doses of inhaled salbutamol either by metered-dose inhaler (mdi) alone, or in conjunction with a pear shaped spacer attachment (pss). dose increments were made every 20 min from 100 micrograms to 2000 micrograms. 2. plasma potassium (k), electrocardiographic (ecg) and haemodynamic (hr, sbp and dbp) responses were measured at each dose increment. 3. there were falls in k (as mean and 95% ci) in response to salbutamol (p less than 0.001): 3.7 ... | 2006 | 2547409 |
[pseudotumor of the shoulder after massive osteolysis (gorham-stout)]. | 1989 | 2536489 | |
[ameson hybomitrae sp. n. (microsporidia, pereziidae) from gadflies of karelia]. | microsporidia of the genus ameson were recorded from larvae of horseflies of the genus hybomitra in karelia. earlier these microsporidia were recorded from crustaceans. the infection extensiveness ranges from 5.1 to 10.5%. the parasites develop in musculature, fat body and salivary glands of the host. the new species has uninucleate, single-located egg- and pear-shaped spores. the ultrafine structure of developmental stages and spores is studied. | 2009 | 2524029 |
types of neurons in nucleus olivaris inferior of the european bison. | the studies were carried out on the medullae oblongatae of four european bisons. preparations made by means of the golgi technique, as well as preparations stained by the klüver-barrera methods, were used. two types of neurons were distinguished in nucleus olivaris inferior of the european bison. type i (about 90% of neurons) are multipolar cells whose perikaryons measure from 25 to 40 microns. the multipolar cells generate 5-6 thick dendrites which next give off a number of branches. the dendri ... | 1988 | 2458411 |
structural organization of the optic tectum of barbus meridionalis risso. i. inner strata (spv, sac and sgc). | the histological features of the three deepest strata of the optic tectum of barbus meridionalis were studied with several staining and impregnation techniques. the boundaries between spv, sac and sgc were easily established and furthermore the myelinization pattern of the sac is described. several neuronal types were distinguished according to their dendritic and axonal features. pyriform multipolar neurons were found in the spv; in the sac, pear-shaped, horizontal and multipolar neurons; in th ... | 1986 | 2423582 |
negative staining of myosin molecules. | a reproducible method has been developed for the negative staining of myosin molecules. the dimensions of stained molecules are in close agreement with those obtained by metal shadowing. sharp bends in the tail, indicative of hinge regions, were observed at two positions 44 nm and 76 nm from the head-tail junction. the tail was often ill-defined at the position of the first (44 nm) bend. the bend positions may be sites of proteolytic cleavage that result in the production of long and short myosi ... | 1985 | 2413217 |
three new species of eimeria (apicomplexa: eimeriidae) from apalone spinifera pallidus (testudines: trionychidae) in texas, with a redescription of e. amydae. | three new species of eimeria are described from pallid spiny softshells, apalone spinifera pallidus, collected in north-central texas. oocysts of eimeria spinifera n. sp. were found in the feces of 3/9 (33%) turtles and are subspheroid, ellipsoid, or pear-shaped, 16.3 x 14.0 (14-19 x 12-18) microns, with a thin, single-layered wall; shape index 1.2 (1.1-1.3). a micropyle is absent, but an oocyst residuum is present; polar granule present in 16% of the oocysts. sporocysts are elongate-ovoid, 10.3 ... | 1990 | 2380856 |
morphology of the human olfactory epithelium. | the human olfactory epithelium has been previously studied with scanning electron microscopy; however, most studies have been limited to examining the epithelial surface. in an attempt to examine structures below the surface, we scanned epithelial fractures that occurred during tissue preparation. this made it possible to obtain unique three-dimensional images of cell profiles from the mucosal surface through the full depth of the epithelium. we examined supporting cells, olfactory neurons, basa ... | 1990 | 2376627 |
the effect of storage of canned juices on content of the metals fe, cu, zn, pb, sn, al, cd, sb and ni. | the increase in concentration of iron, copper, zinc, lead, antimony, aluminium, cadmium, tin and nickel over a 2 year's time of juices of peach (prunus persica), pear (pyrus communis), apricot (prunus vulgaris) and apple (malus pumila) was determined. the results show a considerable increase in fe, cu, pb, zn and sn with time, while the change in al, cd, ni and sb is negligible. | 1990 | 2366854 |
radiotherapy of morbus gorham-stout: the biological value of low irradiation dose. | morbus gorham-stout is a very rare disease. a patient with this disease was treated at the university clinic of radiobiology in vienna. the clinical and radiological findings place special emphasis on the radiotherapeutic treatment, and the biological basis of the recommended dose is discussed. | 1990 | 2334833 |
the effect of whole ejaculate filtration on the morphology and the fertility of bovine semen. | a sephadex g-15 filtration method was developed to remove abnormal and nonmotile bull sperm from an entire ejaculate. the efficiency of filtration was determined by adding freeze-killed sperm to the ejaculate or using ejaculates with elevated numbers of abnormal cells induced by scrotal insulation. a fertility trial, using split ejaculates, compared fertility of filtered and unfiltered semen. after filtration, samples with 0, 25, and 50% killed cells added contained 77 to 81% motile cells. addit ... | 1990 | 2312886 |
structural and antigenic analysis of chlamydia pneumoniae. | several isolates of chlamydia pneumoniae were compared with each other and to chlamydia trachomatis and chlamydia psittaci by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblots. protein profiles of the c. pneumoniae isolates appeared to be the same and were distinct from the other chlamydia species. a 39.5-kilodalton (kda) protein, similar in molecular weight to the major outer membrane proteins (momp) of c. trachomatis and c. psittaci, was found in the sarkosyl-insoluble ... | 1990 | 2294060 |
[the psychopathologic picture of incipient schizophrenia in the male population at approximately 20 years of age]. | as the diagnosis of initial schizophrenic psychosis is sometimes difficult and the diagnosis of schizophrenia is based on psychopathological characteristics the author used the relative homogenity of their cases for comparison with various known concepts and scales in an attempt to contribute to the serious problem of assessment of this nosological unit. psychopathological descriptions of 45 cases of first hospitalizations on account of schizophrenia of men aged 18-24 years were investigated wit ... | 1990 | 2261655 |
auditory epithelial migration on the human tympanic membrane: ii. the existence of two discrete migratory pathways and their embryologic correlates. | the pathways of movement of dye-markings on the tympanic membranes of 30 ears of 15 volunteers were investigated by photography with a hopkin's rod. two discrete pathways were identified. movement on the pars tensa was centrifugal in all directions from the edge of the handle of malleus surface. this supported our previous suggestion that pars tensa epithelial migration is based on growth of the meatal plate. movement on the more central part of the handle surface itself, however, was always upw ... | 1990 | 2260527 |
pectin isolated from prickly pear (opuntia sp.) modifies low density lipoprotein metabolism in cholesterol-fed guinea pigs. | the effect of prickly pear soluble fiber on low density lipoprotein (ldl) metabolism was investigated by feeding male guinea pigs either a nonpurified diet containing 0.25% cholesterol (hc diet) or the hc diet + 1% prickly pear pectin (hc-p diet). plasma cholesterol levels were significantly decreased by the hc-p diet, with a 33% decrease in ldl levels (p less than 0.02) and an increase in ldl density. hepatic free and esterified cholesterol levels were reduced 40 and 85%, respectively (p less t ... | 1990 | 2231018 |
the rcsa gene from erwinia amylovora: identification, nucleotide sequence, and regulation of exopolysaccharide biosynthesis. | rcsa is a positive activator of extracellular polysaccharide synthesis in the enterobacteriaceae. a cosmid clone containing the rcsa gene from erwinia amylovora was identified by its ability to restore mucoidy to an e. stewartii rcsa mutant. the rcsa gene was subcloned on a 2.2-kilobase hindiii-psti fragment that hybridized with an e. stewartii rcsa probe and complemented e. stewartii and escherichia coli rcsa mutants. in addition, the cloned e. amylovora rcsa gene stimulated expression of cps:: ... | 1990 | 2131100 |
effect of the new spacer-device on the deposition of the inhaled metered dose aerosol. | the effect of the new spacer-device on the in vitro and in vivo deposition of inhaled drug particles was studied. the in vitro deposition of beclomethasone dipropionate 250 micrograms/dose aerosol administered either through the conventional aerosol actuator with the short plastic mouthpiece or through the new pear-shaped spacer-device was evaluated with the modified cascade impactor method. for the in vivo study the disodium cromoglycate particles were labelled with a pure gamma-radiator 99mtc ... | 1990 | 2129249 |
cloning of a large gene cluster involved in erwinia amylovora cfbp1430 virulence. | phage mudiipr13 insertional mutagenesis of erwinia amylovora cfbp1430 allowed us to isolate 6900 independent cmr mutants. the frequencies of different auxotrophs in this population indicated that mudiipr13 had inserted randomly in e. amylovora. screening of 3500 cmr mutants on (i) apple calli and (ii) pear and apple seedlings led to the isolation of 19 non-pathogenic prototrophic single mutants, four of which expressed a lacz+ hybrid protein. expression of the fusion proteins was temperature sen ... | 1990 | 2117695 |
musculoskeletal case of the day. gorham syndrome of the right clavicle and scapula. | 1990 | 2110757 | |
experimental life history of spirometra erinacei. | the complete life cycle of spirometra erinacei has been experimentally maintained in the laboratory. the cyclops were reared as the first intermediate host, and the tadpoles of rana nigromaculata as the second intermediate host. icr mice were used as another second host. the experimental definitive hosts were dogs and cats. maturation and hatching of the eggs took 8 to 14 days by incubation at 29 degrees c. the coracidium measured 43.8 x 36.9 microns. mesocyclops leuckarti and eucyclops serrulat ... | 1990 | 2095198 |
the initiation and organization of microtubules in germinating pear (pyrus communis l.) pollen. | to study microtubule organization in germinating pear (pyrus communis l., cv., bartlett) pollen, we removed the pollen wall by freeze-fracturing before treating the resultant pollen protoplasts by conventional immunofluorescence procedures. results reveal that axial bundles of microtubules are present in the generative cell of both inactivated and activated pollen grains. microtubules are not present in the vegetative cells of inactivated pollen, but they are present in the vegetative cells of a ... | 1990 | 2081552 |
[iconographic rubric. gorham disease]. | 1990 | 2078112 | |
massive pelvic osteolysis in the gorham-stout syndrome. | massive osteolysis is a very rare tumour-like lesion usually affecting young adults. there are 132 reported cases which we have reviewed, including 31 single cases of pelvic involvement. the term "massive osteolysis" is based on the typical radiological findings, such as increasing translucency and loss of bone density. the diagnosis of the gorham-stout syndrome must be confirmed by the microscopic finding of intramedullary vascular structures. our patient was a 23 year old white caucasian, who ... | 1990 | 2076919 |
stereographic and stereometric study of sebaceous gland hyperplasia in rabbit pinnas induced by topically applied substances. | tetradecane (td), testosterone (ts), and dimethyl sulfoxide (dmso) were separately inuncted on rabbit pinnas once a day; the pinnas were biopsied on days 1, 3, 7, and 28. untreated pinnas and squalane-treated pinnas were used as controls. three-dimensional images of sebaceous glands were reconstructed from their serial histologic sections using a computer-image analysis system. by stereometry, the sebaceous gland volumes gradually increased during the course of treatments with ts and dmso, where ... | 1991 | 2056196 |
[essential osteolysis. study of 3 cases and a classification trial]. | disappearing bone disease is a rare syndrome, characterized by an idiopathic and spontaneous progressive resorption of bone, for which different etiologies must be considered. the classification of this disease is difficult; acro-osteolysis involves the phalanges or the carpus and tarsus. massive osteolysis corresponds to diffuse multicentric cystic hemangiomatosis and gorham and stout's disease. we describe two cases of acro-osteolysis and one of gorham and stout's disease. the mechanism of dis ... | 1991 | 2048871 |
identification of a new viroid as the putative causal agent of pear blister canker disease. | a small rna species with the structural and functional properties characteristic of viroids has been isolated from three different pear sources each of which induced symptoms of the pear blister canker (pbc) disease when indexed in the pear indicator a 20. a close association between this rna and pbc disease was established, since two of the three studied sources were known to be affected by this malady only, and the viroid was not detected in healthy pear tissue. moreover, the pbc-associated vi ... | 1991 | 2045786 |
glutamic acid decarboxylase (gad)-immunoreactive structures in the adult human lateral geniculate nucleus. | the distribution of glutamic acid decarboxylase (gad)-like immunoreactivity in the lateral geniculate nucleus (lgn) of the human adult was studied in vibratome sections (50-60 microns thick) using the avidinbiotin-peroxidase method. the tissue was obtained at autopsy from five individuals without any known neurological disorders. only few gad-immunoreactive neurons were present in the layers of the lgn, even less in the interlaminar zones. the numerical density of gad-immunoreactive neurons and ... | 1991 | 2035846 |
nucleotide sequence and taxonomic value of the major outer membrane protein gene of chlamydia pneumoniae iol-207. | chlamydia pneumoniae iol-207 genomic dna was hybridized with a 1.5 kb labelled dna probe containing the 3' region of the coding sequence for the major outer membrane protein (momp) of c. trachomatis serovar l1. an 8.5 kb bg/ii fragment containing the complete momp gene was cloned into lambda embl3. two hybridizing ecori fragments were sub-cloned into the lambda zap ii cloning vector and the resulting plasmids were used as templates for sequencing both strands of the c. pneumoniae momp gene. comp ... | 1991 | 2033374 |
how does the toad's visual system discriminate different worm-like stimuli? | behavioral experiments show that toads exhibit stimulus- and locus-specific habituation. different worm-like stimuli that toads can discriminate at a certain visual location form a dishabituation hierarchy. what is the neural mechanism which underlies these behaviors? this paper proposes that the toad discriminates visual objects based on temporal responses, and that discrimination is reflected in different average neuronal firing rates at some higher visual center, hypothetically anterior thala ... | 1991 | 2004136 |
a novel endocrine cell type in the guinea-pig gastric mucosa: cellular source of pro-enkephalin-derived peptides. a histochemical, immunohistochemical, and electron microscopical characterization. | a novel endocrine cell type has been identified in the guinea-pig gastric mucosa which preferentially occurs in the oxyntic area. cells of this type exhibit immunoreactivities for bovine adrenal medulla dodecapeptide (bam-12p) and in many cases for met-enkephalin and are thus presumed to contain a pro-enkephalin-like precursor protein. systematic immunohistochemical investigations show that these cells do not contain immunoreactivities for various enteric hormones, neuropeptides and biogenic ami ... | 1990 | 1972145 |
immunohistochemical localization of glutamine synthetase in mesencephalon and telencephalon of the lizard gallotia galloti during ontogeny. | the immunohistochemical localization of glutamine synthetase, an astrocyte marker in mammals, was determined in the telencephalon and mesencephalon of the lizard gallotia galloti during development by using an antiserum raised against chicken brain glutamine synthetase. ependymal glial cells and their radial processes were glutamine synthetase immunoreactive, and they were present also in the adult. immunoreactivity was also detected in two populations of scattered cell bodies, each preferential ... | 1990 | 1970551 |
[contractile function, extracardiac regulation and morphological changes in the hearts of rats in the dynamics of a long-term continuously acting stressor situation]. | 24 hrs of the overpopulation stress effect induced a set of shifts typical for an acute stress syndrome in rats. within 5 days the organism mobilizes the cholinergic stress-limiting system functioning for 15 days, limiting and normalizing the contractile function (cf) of the heart, and eliminating the contracture damages of the myocardium on the 30th day. starting from the 30th day of the stress effect, adrenergic features of the extracardiac regulation (er) re pear, the cf parameters increase, ... | 1990 | 1966085 |
scanning electron microscopic study of odontoblasts and circumpulpal dentin in a human tooth. | two combined scanning electron microscopic methods including modified fixative procedures were used for studying the morphologic aspects of the odontoblasts and the corresponding dentinal wall at different endodontic levels. the odontoblasts were tightly packed in the pulp horn, where they assumed pear-shaped profiles and, from crown to apex, successively looked spindle shaped, club shaped, and globular. their number decreased in the pulp radicular portion, where the interglobular spaces were en ... | 1991 | 1923448 |
motor neurons and motor columns of the anterior spinal cord of salamanders: posthatching development and phylogenetic distribution. | the posthatching development of rostral (1st-4th) spinal motor neurons was studied in ten species of salamanders, using horseradish peroxidase and cobaltic lysine tracing techniques. development of spinal motor neurons differs among species in association with differences in life history and general developmental patterns (i.e., between species with aquatic larvae versus those with direct development, with or without ontogenetic repatterning). in the plesiomorphic state, represented by species w ... | 1991 | 1913139 |
three-dimensional structure of myosin subfragment-1 from electron microscopy of sectioned crystals. | image analysis of electron micrographs of thin-sectioned myosin subfragment-1 (s1) crystals has been used to determine the structure of the myosin head at approximately 25-a resolution. previous work established that the unit cell of type i crystals of myosin s1 contains eight molecules arranged with orthorhombic space group symmetry p212121 and provided preliminary information on the size and shape of the myosin head (winkelmann, d. a., h. mekeel, and i. rayment. 1985. j. mol. biol. 181:487-501 ... | 1991 | 1869586 |
ultrastructure of chlamydia pneumoniae in cell culture. | the electron microscopic appearance of chlamydia pneumoniae elementary bodies with pear-shaped, loose outer membrane has been suggested as one criterion of its classification as a new chlamydial species. the study of the original strain tw 183 in lcl 929 and hl cells and a low-passage isolate of kajaani-6 isolate in hl cells revealed spherical compact elementary bodies common to other chlamydia. | 1991 | 1778435 |
suspected avocado (persea americana) poisoning in goats. | a herd of 15 cameroon goats was suspected of having been poisoned by eating leaves of the fuerte variety of avocado pear (persea americana). two of the affected goats were examined clinically, while necropsies were carried out on 3 of the 4 that had died. the most significant clinical findings were tachycardia, hyperpnoea and evidence of lung oedema. at necropsy severe lung oedema, hydrothorax and hydropericardium were present. severe myocardial degeneration, necrosis and fibrosis were the major ... | 1991 | 1770497 |
[the malignant degeneration of gorham-stout disease?]. | 1991 | 1764602 | |
developmental lymphatic disorders of the thorax. | developmental disorders that involve the lymphatic channels of the thorax, although rare, are important and must be distinguished from the more common causes of chest masses or diffuse lung disease. there are four major types of developmental lymphatic disorders that affect the thorax: lymphangiectasis, characterized by congenital anomalous dilatation of pulmonary lymph vessels; localized lymphangioma, a rare and benign, usually cystic, lesion characterized by masslike proliferation of lymph ves ... | 1991 | 1749850 |
localization of neuropeptide-immunoreactive neurons in the human retina. | light microscopic immunocytochemistry was utilized to localize populations of neurons in the human retina immunoreactive for the following neuroactive peptides: substance p (sp), vasoactive intestinal polypeptide (vip), somatostatin (som) and lant-6-(h-lys-asn-pro-tyr-ile-leu-oh), a hexapeptide which is identical to the c-terminal half of neurotensin except for the amino acid substitutions lys/arg and asn/arg. the majority of sp immunoreactive cells were amacrine cells whose pear-shaped or oval ... | 1990 | 1699634 |
protein phosphatase 2a in saccharomyces cerevisiae: effects on cell growth and bud morphogenesis. | we have cloned three genes for protein phosphatases in the yeast saccharomyces cerevisiae. two of the genes, pph21 and pph22, encode highly similar proteins that are homologs of the mammalian protein phosphatase 2a (pp2a), while the third gene, pph3, encodes a new pp2a-related protein. disruptions of either pph21 or pph22 had no effects, but spores disrupted for both genes produced very small colonies with few surviving cells. we conclude that pp2a performs an important function in yeast cells. ... | 1991 | 1656215 |
first heterotransplantation of a human carcinoid tumor into nude mice. | the first successful heterotransplantation of a human carcinoid tumor into nude mice is reported. csh, a voluminous hepatic metastasis of a primary bronchial carcinoid tumor (csb) was resected and transplanted into three irradiated nude (swiss-nu/nu) mice both by subcutaneous (sc) and intramuscular (im) routes; the success rate was five of six. heterotransplanted tumors took 4 to 5 months to appear in the mice and 1 month to attain a width of 0.5 cm. both human and mouse tumors (named csh-sc and ... | 1991 | 1649689 |
effects of ethanol and various alcoholic beverages on the formation of o6-methyldeoxyguanosine from concurrently administered n-nitrosomethylbenzylamine in rats: a dose-response study. | consumption of alcoholic beverages has been identified as a major cause of oesophageal cancer in industrialized countries, with an exceptionally high risk associated with apple-based liquors (calvados). in the present study, we have determined the dose--activity relationship of the effects of coincident ethanol on the formation of o6-methyldeoxyguanosine (o6-medg) by the oesophageal carcinogen n-nitrosomethylbenzylamine (nmbza). male fischer 344 rats received a single intragastric dose of nmbza ... | 1992 | 1638683 |
harpin, elicitor of the hypersensitive response produced by the plant pathogen erwinia amylovora. | a proteinaceous elicitor of the plant defense reaction known as the hypersensitive response was isolated from erwinia amylovora, the bacterium that causes fire blight of pear, apple, and other rosaceous plants. the elicitor, named harpin, is an acidic, heat-stable, cell-envelope-associated protein with an apparent molecular weight of 44 kilodaltons. harpin caused tobacco leaf lamina to collapse and caused an increase in the ph of bathing solutions of suspension-cultured tobacco cells. the gene e ... | 1992 | 1621099 |
[inhibitory effects of balsam pear on the mutagenic activity of cyclophosphamide in vivo]. | inhibitory effects of balsam pear on the mutagenic activity of cyclophosphamide were studied in the cells of bone marrow of mouse in vivo. it was found that balsam pear juice itself showed no effect on the incidence of sister chromatid exchanges (sce) and of micronuclei (mn) on the cells of bone marrow. but balsam pear juice reduced the incidence of sce (from 29.1 times/cell to 13.27-28.38 times/cell) and mn (from 60.0% to 27.0%-50.0%) induced by cyclophosphamide respectively. the inhibitory eff ... | 1992 | 1606864 |
3-oxoacyl-[acp] reductase from oilseed rape (brassica napus). | 3-oxoacyl-[acp] reductase (e.c. 1.1.1.100, alternatively known as beta-ketoacyl-[acp] reductase), a component of fatty acid synthetase has been purified from seeds of rape by ammonium sulphate fractionation, procion red h-e3b chromatography, fplc gel filtration and high performance hydroxyapatite chromatography. the purified enzyme appears on sds-page as a number of 20-30 kda components and has a strong tendency to exist in a dimeric form, particularly when dithiothreitol is not present to reduc ... | 1992 | 1562581 |
synaptic connections of central carotid sinus afferents in the nucleus of the tractus solitarius of the rat. i. an electron microscopic study. | a transganglionic transport technique was used to study the synaptic connections of the central carotid sinus afferents in the nucleus of the tractus solitarius of the rat by electron microscopy. the caudal part of the nucleus was profusely innervated. labelled fibres extended to the contralateral nucleus, and to the ipsilateral dorsal motor nucleus of the vagus nerve, nucleus ambiguus, spinal nucleus of the trigeminal nerve and the area postrema. the labelled terminals were densely packed with ... | 1992 | 1560250 |
refractory barriers in the sand fly phlebotomus papatasi (diptera: psychodidae) to infection with leishmania panamensis. | the life cycle of leishmania panamensis in phlebotomus papatasi was studied to characterize barriers limiting parasite colonization, differentiation, migration, and attachment in an unnatural sand fly host. the insects were fed a suspension of l. panamensis-infected macrophages and human erythrocytes, and were examined up to 16 days post-infection by light and electron microscopy. histologic examination of 401 flies showed the peritrophic membrane to be the first important barrier to parasite es ... | 1992 | 1539756 |
some observations on the fine structure of the sensory cells in the neuromasts (ordinary lateral line) of the teleost gambusia affinis. | the structural and ultrastructural features of the sensory cells in the neuromasts of g. affinis were studied. these pear-shaped cels present a tuft of sensory hairs rising from the apex and a highly dense cytoplasm with multivesicular bodies, dyctiosomes, granular and smooth endoplasmic reticulum and numerous mitochondria. large round granular dense bodies of an unknown nature can be observed inside and outside the nucleus. a great number of vesicles are present at the base of the cells, some o ... | 1992 | 1447513 |
central projections and motor nuclei of the facial, glossopharyngeal, and vagus nerves in the mormyrid fish gnathonemus petersii. | most of the information about the anatomy of the fish's cranial nerves was collected in the first two decades of this century. experimental analysis of the viith, ixth, and xth cranial nerves by modern tract tracing techniques started about 20 years ago. several species have been investigated to date, including one species of agnatha (myxinoidea), two species of elasmobranchs, and species of some orders of teleostei like cyprinidae, siluriformes, perciformes, and gadidae. the sensory and motor n ... | 1992 | 1447406 |
gamma-aminobutyric acid immunoreactivity in the enterochromaffin cells of the rat stomach. | the present immunocytochemical study revealed gamma-aminobutyric acid (gaba) immunoreactivity in the oxyntic and pyloric mucosa of the rat stomach at light- and electron-microscopic levels. gaba-immunoreactive endocrine cells were numerously seen in the lower half portion of the pyloric mucosa but rarely in the oxyntic mucosa. these cells were round or oval in shape and sometimes had a short cytoplasmic process. serotonin-immunoreactive enterochromaffin (ec) cells were also observed in the oxynt ... | 1992 | 1441883 |
[gorham disease disclosed by pathological fracture]. | 2016 | 1410904 | |
[morphology and immunotyping of ac-43 strain of chlamydia pneumoniae isolated from a japanese child]. | a strain of chlamydia pneumoniae (c. pneumoniae) which had been isolated from a japanese child (ac-43) was examined morphologically and serologically using micro-immunofluorescent (micro-if) test. inclusions of ac-43 were stained by an indirect immunofluorescent method using c. pneumoniae specific monoclonal antibody. they were dense round inclusions which had been reported as a characteristic figure for c. pneumoniae. an elementary body (eb) of ac-43 was pear-shaped by electron micrograph, whic ... | 1992 | 1402097 |
pear blister canker viroid is a member of the apple scar skin subgroup (apscaviroids) and also has sequence homology with viroids from other subgroups. | the sequence of pear blister canker viroid (pbcvd), the putative causal agent of pear blister canker (pbc) disease, has been determined. pbcvd consists of a single-stranded circular rna of 315 nucleotide residues which assumes a branched conformation when it is folded in the model of lowest free energy. pbcvd has highest sequence similarity with grapevine 1b viroid (52.4%), but also contains sequences related to regions present in viroids that belong to different subgroups, suggesting that pbcvd ... | 1992 | 1383394 |
expression of erwinia amylovora hrp genes in response to environmental stimuli. | seven hrp loci that are essential for the hypersensitive reaction elicited by erwinia amylovora were transcriptionally fused with a derivative of transposon tn5, containing the promoterless escherichia coli beta-glucuronidase reporter gene. the seven hrp fusions were used to monitor expression of the hrp loci in vitro and in planta. no significant expression was detected in rich medium for any of the fusions. however, five of them were expressed highly in planta and in inducing medium that conta ... | 1992 | 1372313 |
[demonstration of sensor nervous endings in the rat thyroid gland]. | the nerve sensitive endings or receptors of the thyroid gland have been studied in twenty adult male rats. their morphology, their acetyl-cholinesterase specific activity, their mono-amino-oxidase activity and vip were investigated. few but constant nerve sensitive endings were observed in the thyroid gland. these receptors were subdivided by their morphology in the next groups: pear-shaped receptors with capsule; capsuled spherical receptors located near vascular walls; ovoidal receptors with c ... | 1991 | 1366352 |
prickly pear (opuntia sp.) pectin reverses low density lipoprotein receptor suppression induced by a hypercholesterolemic diet in guinea pigs. | the effects of prickly pear pectin on plasma ldl metabolism were investigated by feeding guinea pigs either a diet containing 15 g/100 g lard and 0.25 g/100 g cholesterol (lc diet) or the lc diet in which cellulose was partially replaced (2.5 g/100 g) by prickly pear pectin (lc-p diet). the lc-p diet lowered plasma ldl cholesterol concentrations by 33% (p < 0.001). low density lipoprotein composition was modified by intake of prickly pear pectin; the relative percentages of free and esterified c ... | 1992 | 1333520 |
localization of transposon insertions in pathogenicity mutants of erwinia amylovora and their biochemical characterization. | transposon tn5, on a mobilizable cole1 plasmid, on a ti plasmid derepressed for bacterial transfer, and on the bacteriophage fd genome, was used to construct pathogenicity mutants of the fire blight pathogen erwinia amylovora. eleven nonpathogenic mutants were isolated from 1600 independent mutants screened. these mutants were divided into three types: auxotrophs, exopolysaccharide (eps)-deficient mutants and a mutant of the dsp phenotype. according to their insertion sites the tn5 mutants were ... | 1992 | 1322951 |
role of antibiotic production by erwinia herbicola eh252 in biological control of erwinia amylovora. | erwinia herbicola eh252 is a nonpathogenic epiphytic bacterium that reduces fire blight incidence when sprayed onto apple blossoms before inoculation with erwinia amylovora, the causal agent of fire blight. eh252 was found to produce on minimal medium an antibiotic that inhibited the growth of e. amylovora. this antibiotic was inactivated by histidine but not by fe(ii), was sensitive to proteolytic enzymes, and showed a narrow host range of activity. to determine the role of this antibiotic in t ... | 1992 | 1314801 |
two-dimensional crystals of membrane-bound gastric h,k-atpase. | two-dimensional crystallization of membrane-bound h,k-atpase (ec 3.6.1.36) in vesicle preparations from parietal cells of hog gastric mucosa was induced by an imidazole buffer containing mg2+ and vo3- ions. a continuous reorganization of the protein molecules started within a few hours by the formation of linear arrays. at later stages confluent two-dimensional crystals were formed. electron microscopy and image processing showed that these were of a single tetragonal type. the asymmetric unit c ... | 1992 | 1312039 |
comparative analysis of tissue esterases of the zebra danio (brachydanio rerio) and the pear danio (b. albolineatus) by disc gel electrophoresis. | 1978 | 1277802 | |
development of the voicing contrast: a comparison of voice onset time in stop preception and production. | the acoustic cue voice onset time (vot) was used to study development of the voicing contrast in 10 two-year-old children, 10 six-year-old children, and 20 adults. thirty utterances of the words bees, peas, bear, pear, dime, time, goat, and coat were elicited from each subject, vot measured, and individual production distributions for labial, apical, and velar stops plotted. significant age-related differences were shown for mean vot, mean lead time for voiced stops, range of the same words that ... | 1976 | 1271805 |
degradation of endosulfan and ethion on pears and pear and grape foliage. | 1967 | 1270675 | |
[osteolysis of the bones of tarsus, metatarsus and articles of fingers during haemangioendothelioma. peripheral form similar to gorham-stout syndrome (author's transl)]. | 1976 | 1269036 | |
pilum pilum gen. et sp. n. (acanthocephala: echinorhynchidae) from freshwater fishes of the southeastern united states. | pilum pilum gen. et sp. n. is described from the warmouth, lepomis gulosus (cuvier); brown bullhead, ictalurus nebulosus (lesueur); yellow bullhead, i. natalis (lesueur); redbreast sunfish, l. auritus (linnaeus); bluegill, l. macrochirus rafinesque; spotted sunfish, l. punctatus (valenciennes); and redfin pickerel, esox americanus (gmelin), from the alabama river drainage, brown bullhead from the mobile bay drainage in alabama, and pirate perch, aphredoderus sayanus gilliams, from an atlantic co ... | 1976 | 1255353 |
[the use of the brief psychiatric rating scale (bprs) by overall and gorham for the diagnosis of acute paranoid psychoses: evaluation of a german translation of the bprs (author's transl)]. | a german translation of overall and gorham's "brief psychiatric rating scale" (bprs) has been used to select patients with acute paranoid psychoses for a drug trial and to evaluate the results of the treatment. the bprs proved very useful in screening, and as a reliable method to judge the global therapeutic outcome. the total score showed a high degree of interrater reliability; it also reflected a marked decrease of psychopathological symptoms at the end of the trial. interrater correlation co ... | 1975 | 1233522 |
[yeast flora of plant rhizosphere and phyllosphere]. | the species belonging to the genera cryptococcus and hansenula with saturnian spores predominate in the rhizosphere of agricultural plants. the sporiferous strains of debaryomyces, hanseniaspora apiculata, metschnikowia pulcherrima, and asporogenic candida krusei and trichosporon cutaneum prevail in the rhizosphere of wild plants. candida krusei and trichosporon cutaneum prevail in the rhizosphere of wild plants. the cultures of rhodotorula, candida krusei and metschnikowia pulcherrima are typic ... | 1975 | 1226148 |
development of the voicing contrast: perception of stop consonants. | perceptual development of the voicing contrast was investigated in two-year-old children, six-year-old children, and adults. subjects were required to identify prevocalic stop consonants from synthetic speech stimuli--bees/peas, bear/pear, dime/time, and goat/coat. the stimuli differed with respect to the acoustic cue, voice onset time (vot). identification functions for labial, apical, and velar stops were plotted for each subject. measurements of 50% crossover, lower and upper limits of the ph ... | 1975 | 1186163 |
[current status of the clinical evaluation of psychotropic drugs]. | this paper deals with the analysis of different research conceptions and designs, according to different areas: i. human pharmacology and toxicology; ii. therapeutic prescriptions; iii. therapeutic effects; iv. thorough clinical testing. there is a strongly felt -eed of universally acknowledged rating scales for the assessment of the effects psychothropic drugs have on mental diseases. the lack of experimental models, together with the wide span of psychodinamic conceptions, overemphasizes the n ... | 1975 | 1163268 |
comparative microscopical study of the gall bladder mucosa. | the gall bladder from 6 psammophis sibilans, 10 bufo regularis and 10 albino mice were extracted and prepared for microscopic examination. it was found that the mucosa of psammophis sibilans consisted of ovoid and polygonal cells which were occasionally binucleated cells with darkly stained nuclei and occasionally pear-shaped cells with vesicular nuclei and fine processes. these cells were arranged in three layers. apossible explanation for the different types of cells encountered and their arra ... | 1975 | 1136701 |
a comparison of the properties in vitro of biphenyl 2- and 4-hydroxylase in the mesocarp from avocado pear (persea americana) and syrian-hamster hepatic tissue. | 1975 | 1132558 | |
[the state of the neural elements of the intestine in the aging organism]. | the small intestine of the ageing human (15 cases from 70 to 88 years of age) and dogs (20 cases from 15 to 20 years of age) was treated by histological and neuro-histological methods. vacuolic dystrophy of neurons and hyperplasia, thickening of their processes were found. different formations up to 15 in number and from 20 to 60 mkm in size were revealed in the dog small intestine wall along the course of the nerve fibre. they were of pear-like, oval or round shape. inside these formations some ... | 1975 | 1131029 |
conjugational transfer of genes determining plant virulence in erwinia amylovora. | a stable virulent donor strain (ea 178r1-99) of erwinia amylovora can transfer, by conjugation during a 3-h mating period, the gene or genes which determine(s) plant virulence to avirulent recipient strains (ea178-m64s1 and ea178-m173s1) of escherichia amylovora. the virulence of over 200 recombinant clones was tested; they all were as virulent on immature bartlett pear fruits (and, in the smaller series of strains tested, also, on pyracantha twigs) as was the parent donor strain. although the a ... | 1975 | 1126916 |
torulopsis bacarum, torulopsis pustula and torulopsis multis-gemmis sp. nov., three new yeasts from soft fruit. | three new species of yeasts isolated from fresh soft fruit are described. torulopsis pustula was isolated from blackcurrants, torulopsis bacarum from blackcurrants, strawberries and raspberries, and torulopsis multis-gemmis from raspberries. all differ from known species in the test substrates they utilize. in addition, cells of torulopsis pustula often form a bulbous projection near their apices from which budding takes place. these buds are frequently pear- or heart-shaped. | 1975 | 1089748 |
a new species of the genus bullera derx. | a new yeast species, bullera piricola, is described. the three strains studied were all isolated from the pear phylloplane. this species differs from all bullera species known at present by forming symmetrical as well as asymmetrical ballistospores. the problem of its integration into the genus bullera derx is discussed. an amended diagnosis of the genus bullera is given. | 1975 | 1083203 |
acute poisoning in a puppy caused by the balsam pear (momordica charantia). | 1976 | 1047586 | |
light microscopy and scanning electron microscopy of bathmostomum sangeri cobbold, 1879, of elephants. | bathmostomum sangeri is an intestinal parasite of the elephant. males measured 12.15-14.25 mm in length; females measured 14.98-17.68 mm in length. buccal capsule is well-developed and funnel-shaped. there is a raised and transverse fissure ridge around the oral margin. the internal wall of the buccal capsule is raised into a series of circular ridges or lamellae. teeth or cutting plates could not be seen. spicules are stout, wing-like structures. the telamon is pear-shaped, but a gibernaculum i ... | 1976 | 1035986 |