Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| a nonstaining and tasteless hydrophobic salt of chlorhexidine. | chlorhexidine (chx) remains one of the most effective and widely used antiplaque agents around the world, although its side effects still limit a long-term usage as the patient compliance for oral treatment with chx. we hypothesize that a less water-soluble tetracation salt of chx might be able to interact weakly with tooth enamel and oral taste cells, reducing those undesirable side effects of chx. the chlorhexidine tetrapalmitate (chxtp) was obtained and the antimicrobial activity was evaluate ... | 2011 | 21344413 |
| extraction of antioxidants and caffeine from green tea (camelia sinensis) leaves: kinetics and modeling. | the effects of temperature (50, 60, 70, 80, 90 °c) and time (5, 10, 20, 40, 80 min) on catechins and caffeine solubility in water from iranian green tea were investigated, the best combinations of temperature and time extraction with water were 20-40 min, 80 °c for epigallocatechin (egc), epicatechin (ec) and caffeine (caff), and 80 min, 90 °c for catechin (c), epicatechin gallate (ecg) and epigallocatechin gallate (egcg). a mathematical model derived from fick's second law was then used to calc ... | 2010 | 21339166 |
| age-dependent changes in the proteolytic-antiproteolytic balance after alcohol and black tea consumption. | aging is accompanied by changes in the redox balance that is additionally modified by alcohol. ethanol metabolism is connected with generation of free radicals which can damage cell components especially when antioxidant mechanisms are not able to neutralize them. in connection with the necessity of prevention against oxidative consequences, natural antioxidants are looked for. a natural and commonly used component of the diets with antioxidant properties are teas, especially the black tea. this ... | 2011 | 21329467 |
| new phenolic compounds from camellia sinensis l. leaves fermented with aspergillus sp. | two new phenolic compounds, teadenol a (1) and teadenol b (2), were isolated from tea (camellia sinensis l.) leaves fermented with aspergillus sp. (pk-1, farm ap-21280). the chemical structures of 1 and 2 were elucidated based on the analyses of their spectroscopic data. the absolute configurations of the structures of 1 and 2 were also certified by their biosynthetic preparation in the treatment of tea catechins with aspergillus sp. | 2011 | 21327519 |
| root release and metabolism of organic acids in tea plants in response to phosphorus supply. | self-rooted, 10-month-old, uniform tea [camellia sinensis (l.) o. kuntze cv. huangguanyin] plants were supplied for 17 weeks with 0, 40, 80, 160, 400, or 1000μm phosphorus (p) to investigate the effects of p supply on root citrate and malate release, the concentrations of malate and citrate and the activities of acid-metabolizing enzymes in leaves and roots. root malate release and accumulation was induced by both 0 and 40μm p, while root citrate release and accumulation was induced only by 0μm ... | 2011 | 21315475 |
| diverse inhibition of plasminogen activator inhibitor type 1 by theaflavins of black tea. | fruits, vegetables, spices and a variety of teas are suggested for the prevention of many diseases. they encompass active, non-nutritional ingredients called nutraceuticals which are defined as food products that provide health benefits. many nutraceuticals have been tested to identify inhibitors of plasminogen activator inhibitor (pai-1). pai-1 is the major and fast acting physiological inhibitor of fibrinolysis. however, preclinical studies of pai-1 inhibitors have revealed an additional role ... | 2011 | 21308350 |
| interactions of green tea catechins with organic anion-transporting polypeptides. | organic anion-transporting polypeptides (oatps) are multispecific transporters that mediate the uptake of numerous drugs and xenobiotics into cells. here, we examined the effect of green tea (camellia sinensis) catechins on the function of the four oatps expressed in human enterocytes and hepatocytes. uptake of the model substrate estrone-3-sulfate by cells expressing oatp1a2, oatp1b1, oatp1b3, or oatp2b1 was measured in the absence and presence of the four most abundant flavonols found in green ... | 2011 | 21278283 |
| white tea (camellia sinensis kuntze) exerts neuroprotection against hydrogen peroxide-induced toxicity in pc12 cells. | tea is a popular beverage whose consumption is associated with prevention of certain disorders. the objective of the study was to investigate the potential neuroprotective effect of white tea extract (wte) on hydrogen peroxide induced toxicity in pc12 cells. cells were treated with various doses of wte (10-250 µg/ml) before exposition to 250 µm hydrogen peroxide and cell survival was determined through the mtt and ldh assays. oxidative stress was quantified in the cells after treatments as intra ... | 2011 | 21271291 |
| black tea polyphenol inhibits cxcl10 production in oncostatin m-stimulated human gingival fibroblasts. | cxc chemokine ligand 10 (cxcl10) plays an important role in the infiltration of th1 cells and thus in the exacerbation of periodontal disease. theaflavin-3,3'-digallate (tfdg), polyphenol in black tea, has some beneficial effects but the effect of tfdg on cxcl10 production from human gingival fibroblasts (hgfs) is uncertain. in this study, we investigated the mechanisms by which tfdg may inhibit oncostatin m (osm)-induced cxcl10 production in human gingival fibroblasts. tfdg prevented osm-mediat ... | 2011 | 21255696 |
| black and green tea consumption and the risk of coronary artery disease: a meta-analysis. | epidemiologic studies are inconsistent regarding the association between tea consumption and the risk of coronary artery disease (cad). | 2011 | 21248184 |
| sterilization and protection of protein in combinations of camellia sinensis green tea extract and gamma irradiation. | sterilization of milk protein without heating is of great interest. gamma irradiation is a very powerful method to decontaminated casein. gamma-irradiation of proteins in aqueous media at doses higher than 5kgy is known to induce their aggregation (without oxygen) or degradation (in presence of oxygen). camellia sinensis green tea extract addition before irradiation of caseins cow milk proteins was examined. it was found that the presence of c. sinensis green tea extract during irradiation in th ... | 2011 | 21238480 |
| construction, characterization, and preliminary bac-end sequence analysis of a bacterial artificial chromosome library of the tea plant (camellia sinensis). | we describe the construction and characterization of a publicly available bac library for the tea plant, camellia sinensis. using modified methods, the library was constructed with the aim of developing public molecular resources to advance tea plant genomics research. the library consists of a total of 401,280 clones with an average insert size of 135 kb, providing an approximate coverage of 13.5 haploid genome equivalents. no empty vector clones were observed in a random sampling of 576 bac cl ... | 2011 | 21234344 |
| increased plasma concentration of epigallocatechin in mice after orally administering a green tea (camellia sinensis l.) extract supplemented by steamed rice. | we attempted to improve the bioavailability of green tea catechins by using food ingredients. the catechin bioavailability of a green tea extract administered to mice was significantly (p<0.05) increased by supplementing with steamed rice. this enhanced bioavailability was due to the increased concentration of plasma non-gallated catechins, especially epigallocatechin (egc). | 2011 | 21228465 |
| plasma pharmacokinetics of catechin metabolite 4'-o-me-egc in healthy humans. | background: tea is an infusion of the leaves of the camellia sinensis plant and is the most widely consumed beverage in the world after water. green tea contains significant amounts of polyphenol catechins and represents a promising dietary component to maintain health and well-being. epidemiological studies indicate that polyphenol intake may have potential health benefits, such as, reducing the incidence of coronary heart disease, diabetes and cancer. while bioavailability of green tea bioacti ... | 2011 | 21212969 |
| effect of green tea powder (camellia sinensis l. cv. benifuuki) particle size on o-methylated egcg absorption in rats; the kakegawa study. | tea polyphenols, e.g., (-)-epigallocatechin-3-o-(3-o-methyl gallate (egcg3"me), (-)-epigallocatechin-3-o-gallate (egcg), (-)-epigallocatechin (egc), (-)-epicatechin-3-o-gallate (ecg), and (-)-epicatechin (ec), are believed to be responsible for the beneficial effects of tea. 'benifuuki', a tea (camellia sinensis l.) cultivar grown in japan, is rich in the anti-allergic molecule epigallocatechin-3-o-(3-o-methyl) gallate (egcg3"me). pulverized benifuuki green tea powder (bgp) is more widely distri ... | 2011 | 21207145 |
| effects of ocimum sanctum and camellia sinensis on stress-induced anxiety and depression in male albino rattus norvegicus. | the aim of this study was to study the ameliorative effects of ocimum sanctum and camellia sinensis on stress-induced anxiety and depression. | 2010 | 21206619 |
| laboratory studies on weight control and prevention of metabolic syndrome by green tea. | green tea (camellia sinensis, theaceace) is the second most popular beverage in the world and has been extensively studied for its putative disease preventive effects. green tea is characterized by the presence of a high concentrations of polyphenolic compounds known as catechins, with (-)-epigallocatechin-3-gallate (egcg) being the most abundant and most well-studied. metabolic syndrome (mets) is a complex condition that is defined by the presence of elevated waist circumference, dysglycemia, e ... | 2010 | 21193040 |
| black tea polyphenol theaflavin suppresses lps-induced icam-1 and vcam-1 expression via blockage of nf-κb and jnk activation in intestinal epithelial cells. | the aim of this study was to determine the impact of the black tea polyphenol, theaflavin, on the expression of adhesion molecules and activation of lipopolysaccharide (lps)-induced innate signaling in rat intestinal epithelial (rie) cells. | 2010 | 21184129 |
| in vitro protective effects of colon-available extract of camellia sinensis (tea) against hydrogen peroxide and beta-amyloid (aβ((1-42))) induced cytotoxicity in differentiated pc12 cells. | there is mounting evidence that the deposition and aggregation of β-amyloid peptides (aβ) in the brain play a significant role in the development and pathogenesis of alzheimer's disease. there is further evidence that free radical species such as hydrogen peroxide (h(2)o(2)) mediate aβ induced toxicity. previous studies have demonstrated that green tea polyphenols possess neuroprotective properties through their ability to ameliorate oxidative stress induced by free radical species. green tea po ... | 2010 | 21183323 |
| agrobacterium-mediated silencing of caffeine synthesis through root transformation in camellia sinensis l. | tea [camellia sinensis (l.) o. kuntze] is a perennial and most popular non-alcoholic caffeine-containing beverage crop. tea has several constraints for its genetic improvement such as its high polyphenolic content and woody perennial nature. the development of transgenic tea is very difficult, laborious, and time taking process. in tea, regeneration requires minimum 8-12 months. in view of this, attempt has been made in this article to develop a rapid, efficient, and quite economical agrobacteri ... | 2010 | 21181507 |
| black tea improves attention and self-reported alertness. | tea has previously been demonstrated to better help sustain alertness throughout the day in open-label studies. we investigated whether tea improves attention and self-reported alertness in two double-blind, randomised, placebo-controlled, crossover studies. participants received black tea (made from commercially available tea bags) in one condition and placebo tea (hot water with food colours and flavours) similar in taste and appearance to real tea in the other condition. attention was measure ... | 2011 | 21172396 |
| effect on gastric function and symptoms of drinking wine, black tea, or schnapps with a swiss cheese fondue: randomised controlled crossover trial. | to compare the effects of drinking white wine or black tea with swiss cheese fondue followed by a shot of cherry schnapps on gastric emptying, appetite, and abdominal symptoms. | 2010 | 21156747 |
| characterization of armillaria isolates from tea (camellia sinensis) in kenya. | armillaria is a primary root rot pathogen of tea (camellia sinensis) in kenya. the main species presently described in this country are a. mellea and a. heimii. a survey covering fourteen districts of kenya was carried out and forty-seven isolates of armillaria collected. cultural morphology, rhizomorph characteristics, somatic incompatibility and features of basidiomata were used to characterize the isolates, together with molecular analysis based on randomly amplified polymorphic dna (rapd), i ... | 2010 | 21156603 |
| cacl2 improves post-drought recovery potential in camellia sinensis (l) o. kuntze. | drought stress affects the growth and productivity of the tea plant. however, the damage caused is not permanent. the present investigation studies the effect of cacl(2) on antioxidative responses of tea during post-drought recovery. increase in dry mass, proline and phenolic content of leaf with decrease in h(2)o(2) and lipid peroxidation and increased activities of enzymes such as sod, cat, pox and gr in response to increased foliar cacl(2) concentration are indications for the recovery of str ... | 2010 | 21153899 |
| effect on the epigallocatechin gallate/epigallocatechin ratio in a green tea (camellia sinensis l.) extract of different extraction temperatures and its effect on iga production in mice. | we found that the epigallocatechin gallate (egcg)/epigallocatechin (egc) ratio in a green tea (camellia sinensis l.) extract was affected by the extraction temperature. the egcg/egc ratio in the 4 °c extract was around 1:3-4, whereas in the 100 °c extract, it was around 1:0.7. oral administration of the mixture with a high egc ratio (1:2-3 = egcg/egc) resulted in greater iga production by murine peyer's patch cells. | 2010 | 21150115 |
| acute and subchronic oral toxicities of pu-erh black tea extract in sprague-dawley rats. | pu-erh black tea, which is obtained by first parching crude green tea leaves and then undergoes secondary fermentation with microorganisms, has been believed to be beneficial beverages for health for nearly 2000 years in china, japan and taiwan area. but its potential toxicity when administered at a high dose as concentrated extracts has not been completely investigated. | 2010 | 21134434 |
| multimycotoxin uplc-ms/ms for tea, herbal infusions and the derived drinkable products. | in recent years the consumption of tea and herbal infusions has increased. these hot drinks are consumed as daily drinks as well as for medicinal purposes. all tea varieties (white, yellow, green, oolong, black and puerh) originate from the leaves of the tea plant, camellia sinensis. all extracts made of plant or herbal materials which do not contain camellia sinensis are referred as herbal infusions or tisanes. during processing and manufacturing fungal contamination of the plant materials is p ... | 2010 | 21121648 |
| proteomic profiling and redox status alteration of recalcitrant tea (camellia sinensis) seed in response to desiccation. | tea seed is believed to be recalcitrant based on its sensitivity to chilling or drying stress. reactive oxygen species (ros) and alterations in cytosolic redox status have been implicated in intolerance to desiccation by recalcitrant seed, but there is little information available regarding how ros are regulated in seeds susceptible to drying stress. we investigated changes in protein expression and activity in tea embryo in response to desiccation using physiological and proteomic methods. resu ... | 2010 | 21120520 |
| oral diuretic activity of hot water infusion of sri lankan black tea (camellia sinensis l.) in rats. | black tea [camellia sinensis (l.) o. kuntze (family: theaceae)] has been used by sri lankan traditional practitioners to promote diuresis. however, the type and grade of tea is not specified. | 2010 | 21120027 |
| antiobesity effects of green tea catechins: a mechanistic review. | green tea catechins (gtc) are polyphenolic compounds present in the unfermented dried leaves of the plant, camellia sinensis. results from a number of randomized, controlled intervention trials have shown that consumption of gtc (270 mg to 1200 mg/day) may reduce body weight and fat. there are several proposed mechanisms whereby gtc may influence body weight and composition. the predominating hypothesis is that gtc influences sympathetic nervous system (sns) activity, increasing energy expenditu ... | 2011 | 21115335 |
| pu-erh black tea supplementation decreases quinocetone-induced ros generation and oxidative dna damage in balb/c mice. | quinocetone (3-methyl-2-quinoxalinbenzenevinylketo-1,4-dioxide, qct), a new feed antibacterial agent of quinoxaline-1,4-dioxides family, has been used as an animal growth promoter. however, few data about its potential toxicity in vivo were available. in this study, genotoxicity of qct and the relationship with oxidative stress were investigated. balb/c mice with both sexes were administrated with qct (12000, 6000 and 3000 mg/kg/bw, respectively) by gavage acutely. dna damage, generation of reac ... | 2010 | 21112366 |
| green and black tea suppress hyperglycemia and insulin resistance by retaining the expression of glucose transporter 4 in muscle of high-fat diet-fed c57bl/6j mice. | to investigate the preventive effects of tea on hyperglycemia and insulin resistance, male c57bl/6j mice were given a high-fat diet containing 29% lard and also green or black tea ad libitum for 14 weeks. both teas suppressed body weight gain and deposition of white adipose tissue caused by the diet. in addition, they improved hyperglycemia and glucose intolerance by stimulating glucose uptake activity accompanied by the translocation of glucose transporter (glut) 4 to the plasma membrane in mus ... | 2010 | 21105694 |
| green tea extract-induced lethal toxicity in fasted but not in nonfasted dogs. | recent chronic toxicity studies performed on green tea extracts in fasted dogs have revealed some unique dose-limiting lethal liver, gastrointestinal, and renal toxicities. key findings included necrosis of hepatic cells, gastrointestinal epithelia and renal tubules, atrophy of reproductive organs, atrophy and necrosis of hematopoietic tissues, and associated hematological changes. the polyphenol cachetins (a mixture of primarily epigallocatechin gallate [≥55%]; plus up to 10% each of epigalloca ... | 2010 | 21098339 |
| oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (lps)-activated mouse macrophages: structure-activity relationship and molecular mechanisms. | oolong tea theasinensins are a group of tea polyphenols different from green tea catechins and black tea theaflavins. the present study reports the inhibitory effects of oolong tea theasinensins on the expression of cyclooxygenase-2 (cox-2) and underlying molecular mechanisms in lipopolysaccharide (lps)-activated murine macrophage raw264 cells. the structure-activity data revealed that the galloyl moiety of theasinensins played an important role in the inhibitory actions. theasinensin a, a more ... | 2010 | 21082860 |
| mass spectrometric characterization of black tea thearubigins leading to an oxidative cascade hypothesis for thearubigin formation. | thearubigins are the most abundant group of phenolic pigments found in black tea, accounting for an estimated 60-70% of the solids in a typical black tea infusion. fifty years ago the term thearubigins was first introduced and to date the chemical nature of the thearubigins remains largely unresolved, if not mysterious, despite numerous attempts made to clarify their structure. thearubigins isolated from 15 commercial black teas have been analyzed using a strategy combining standard chemical cha ... | 2010 | 21072794 |
| profiles of purine metabolism in leaves and roots of camellia sinensis seedlings. | to determine the metabolic profiles of purine nucleotides and related compounds in leaves and roots of tea (camellia sinensis), we studied the in situ metabolic fate of 10 different (14)c-labeled precursors in segments from tea seedlings. the activities of key enzymes in tea leaf extracts were also investigated. the rates of uptake of purine precursors were greater in leaf segments than in root segments. adenine and adenosine were taken up more rapidly than other purine bases and nucleosides. xa ... | 2010 | 21071429 |
| oxidative stress and antioxidant status in intensely exercising horses administered nutraceutical extracts. | many nutraceuticals are used as equine supplements without their efficacy having been scientifically tested. black tea, cranberries, orange peel and ginger are a few of those nutraceuticals that warrant further study. | 2010 | 21059024 |
| black tea reduces diarrhoea prevalence but decreases growth performance in enterotoxigenic escherichia coli-infected post-weaning piglets. | enterotoxigenic escherichia coli (etec) is a main cause of diarrhoea in humans and piglets. in vitro, black tea extract (bte) has anti-pathogenic properties. anti-diarrhoeal properties of bte were assessed in a pig model of gastrointestinal infection. at weaning (day 0), piglets (n = 96) were randomly assigned to a diet containing 0% (control), 0.4% or 0.8% (wt/wt) bte during 27 days. piglets were orally infected with 6.4 × 10(6) cfu of etec on day 6. faecal consistency, feed intake and body wei ... | 2010 | 21039929 |
| nutrition and nonmelanoma skin cancers. | the incidence of nonmelanoma skin cancer is increasing every year. basal cell carcinoma and squamous cell carcinoma are the two major types of nonmelanoma skin cancer. among other factors, understanding the potential role of nutrients in the development, progression, and treatment of nonmelanoma skin cancer is critical. this contribution provides a review of the nutrients that have been more extensively investigated in the literature with regard to nonmelanoma skin cancer, including dietary fats ... | 2013 | 21034989 |
| safety evaluation of tea (camellia sinensis (l.) o. kuntze) flower extract: assessment of mutagenicity, and acute and subchronic toxicity in rats. | tea (camellia sinensis (l.) o. kuntze, theaceae) flowers possess many physiological functions and have been used in traditional medicines for deodorization, skin care, cough suppressant and expectorant in china. however, there is a little information about its possible toxicity. | 2010 | 21034804 |
| hyperbranched acidic polysaccharide from green tea. | an acidic tea polysaccharide (altps), isolated from green tea ( camellia sinensis ), was characterized as a hyperbranched glycoprotein containing the acidic heteropolysaccharide chains and the protein residues from the results of uv-vis, ftir, one- and two-dimensional nmr, gc, gc-ms, and amino acid analyses. solution properties of altps were investigated by static and dynamic light scattering analyses and viscometry. the results indicated that the viscosity behavior of altps exhibited a typical ... | 2010 | 21028801 |
| differential expression pattern of an acidic 9/13-lipoxygenase in flower opening and senescence and in leaf response to phloem feeders in the tea plant. | lipoxygenase (loxs) is a large family of plant enzymes that catalyse the hydroperoxidation of free polyunsaturated fatty acids into diverse biologically active compounds, collectively named phyto-oxylipins. although multiple isoforms of loxs have been identified in a wide range of annual herbaceous plants, the genes encoding these enzymes in perennial woody plants have not received as much attention. in camellia sinensis (l.) o. kuntze, no lox gene of any type has been isolated, and its possible ... | 2010 | 20969806 |
| black and green tea improves lipid profile and lipid peroxidation parameters in wistar rats fed a high-cholesterol diet. | in the present study, the efficacy of black tea (bt) and green tea (gt) was studied in relation to serum and hepatic oxidative abnormalities in hypercholesterolemic rats. hypercholesterolemia was induced in male wistar rats (8 week old) by feeding them with a high-cholesterol diet (hcd) for 35 days. the experimental rats were given bt and gt as a supplement (7 g/l) via drinking water. increased hepatic and serum lipid profile along with abnormalities in oxidative marker, with a concomitant incre ... | 2010 | 20960086 |
| black tea and theaflavins assist healing of indomethacin-induced gastric ulceration in mice by antioxidative action. | the healing activities of black tea (bt) and the theaflavins (tf) against the indomethacin-induced stomach ulceration were studied in a mouse model. indomethacin (18 mg/kg, p.o.) administration induced maximum ulceration in the glandular portion of the gastric mucosa on the 3rd day, accompanied by increased lipid peroxidation and protein oxidation, depletion of thiol-defense and mucin, as well as reduced expressions of cyclooxygenases (cox) and prostaglandin (pg) e synthesis in the gastric tissu ... | 2010 | 20953434 |
| evaluation of the anxiolytic activity of nr-anx-c (a polyherbal formulation) in ethanol withdrawal-induced anxiety behavior in rats. | the present study investigates the anxiolytic activity of nr-anx-c, a standardized polyherbal formulation containing the extracts of withania somnifera, ocimum sanctum, camellia sinensis, triphala, and shilajit in ethanol withdrawal- (ew-) induced anxiety behavior in rats. ethanol dependence in rats was produced by substitution of drinking water with 7.5% v/v alcohol for 10 days. then, ethanol withdrawal was induced by replacing alcohol with drinking water, 12 hours prior to experimentation. aft ... | 2010 | 20953426 |
| amp-activated protein kinase: 'a cup of tea' against cholesterol-induced neurotoxicity. | disturbances in brain cholesterol metabolism have been linked to alzheimer's disease (ad) pathology. a high-cholesterol diet increases fibrillar amyloid β peptide (aβ) deposition, inflammation, and apoptosis that eventually results in neurodegeneration and learning and memory impairments. in the october 2010 issue of the journal of pathology, lu and colleagues provided a novel and interesting mechanism that explains how quercetin, a flavonoid found at high concentrations in green and black teas, ... | 2010 | 20922714 |
| simultaneous quantification of flavonoids and phenolic acids in plant materials by a newly developed isocratic high-performance liquid chromatography approach. | a simple reversed-phase high-performance liquid chromatographic (rp-hplc) method based on isocratic elution has been developed and validated for the simultaneous quantitation of flavonols (myricetin, quercetin, kaempferol, and isorhamnetin), flavones (luteolin and apigenin), and phenolic acids (chlorogenic, caffeic, ellagic, and rosmarinic acids) as important constituents in fruits, vegetables, and medicinal plants. analysis was achieved on a c18 column at ambient temperature. the wavelengths us ... | 2010 | 20919719 |
| phenolic content and in vitro inhibitory effects on oxidation and protein glycation of some thai medicinal plants. | fifteen medicinal plant extracts were investigated for: total phenolic content and free radical scavenging effect by dpph and abts assays; anti-lipid peroxidation activity by tbars; and for antiglycation activity. the results revealed that the total phenolic content showed good correlation with free radical scavenging by abts (r = 0.721) and anti-lipid peroxidation by tbars (r = -0.659), but showed no correlation with antiglycation. three extracts from tamarindus indica, camellia sinensis and ar ... | 2010 | 20884454 |
| restoration of cardiomyocyte function in streptozotocin-induced diabetic rats after treatment with vanadate in a tea decoction. | diabetes mellitus is associated with abnormal cardiomyocyte ca(2+) transients and contractile performance. we investigated the possibility that an alteration in inositol trisphosphate/phospholipase c (ip₃/plc) signalling may be involved in this dysfunction. phosphatidic acid stimulates cardiomyocyte contraction through an ip₃/plc signaling cascade. we also tested a novel therapeutic intervention to assess its efficacy in reversing any potential defects. diabetes was induced in sprague-dawley rat ... | 2010 | 20874687 |
| simultaneous determination of pyrethrins residues in teas by ultra-performance liquid chromatography/tandem mass spectrometry. | a sensitive and effective method for the simultaneous quantitative determination of pyrethrin residues in teas was developed and validated using ultra-performance liquid chromatography coupled with tandem mass spectrometry (uplc-ms/ms). the six major constituents of the pyrethrins (pyrethrin i and ii, jasmolin i and ii, and cinerin i and ii) were successfully separated and independently confirmed in a single run within approximately 5 min. the multi-residue analysis of pyrethrins in teas involve ... | 2010 | 20869505 |
| the efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review. | this review focuses on the efficacy and safety of effective herbal medicines in the management of hyperlipidemia in human. | 2010 | 20858178 |
| outcomes of 3% green tea emulsion on skin sebum production in male volunteers. | this study was aimed to depict potential effects of stable formulation (water in oil emulsion), containing 3% green tea (camellia sinensis l) extract on skin sebum production in healthy human volunteers. for this purpose formulation was designed using 3% ethanolic green tea extract and abil®em90 was used as an emulsifier. formulation was applied to the cheeks of healthy human volunteers (n=10) for a period of 8 weeks. measurements for skin sebum production were considered using sebumeter mpa 5. ... | 2010 | 20846135 |
| tea flavonoids and cardiovascular health. | the two main types of tea are green and black. both green and black teas are rich dietary sources of flavonoids. available evidence suggests that regular tea consumption may reduce the risk of cardiovascular disease. the cardiovascular health benefits of drinking tea are thought to be largely due to flavonoids. tea intake and intake of flavonoids found in tea have been associated with reduced risk of cardiovascular disease in cross-sectional and prospective population studies. isolated flavonoid ... | 2010 | 20837049 |
| intrinsic apoptosis and nf-κb signaling are potential molecular targets for chemoprevention by black tea polyphenols in hepg2 cells in vitro and in a rat hepatocarcinogenesis model in vivo. | antiproliferative and apoptosis inducing effects of black tea polyphenols (polyphenon-b) on hepg2 cells in vitro and in a rat hepatocarcinogenesis model in vivo were investigated. viability of hepg2 cells was evaluated by the mtt assay, and apoptosis by ao-eb and dapi staining, cell cycle analysis, and annexin v-pi assay. for the in vivo study, male sprague-dawley rats treated with dimethylaminoazobenzene (dab) (0.06%) were used. the expression of bcl-2 and nf-κb family members were analyzed by ... | 2010 | 20828598 |
| formation and inhibition of cholesterol oxidation products in tea-leaf eggs during marinating. | the objectives of this study were to develop a gc-ms method for determination of cholesterol oxidation products (cops) in tea-leaf eggs and study the formation and inhibition of cops as affected by heating time and various ingredients in marinated juice. the various cops in egg and juice samples were extracted by a solvent system of chloroform/methanol (2:1, v/v), followed by purification using a silica cartridge and gc-ms for subsequent separation and quantitation, with high recovery ranges fro ... | 2010 | 20828157 |
| geographical and climatic dependencies of green tea (camellia sinensis) metabolites: a (1)h nmr-based metabolomics study. | the effects of climatic conditions on green tea metabolites in three different growing areas of jeju island, south korea, were investigated through global metabolite profiling by (1)h nuclear magnetic resonance (nmr) spectroscopy. pattern recognition methods, such as principal component analysis (pca) and orthogonal projection on latent structure-discriminant analysis (opls-da), revealed clear discriminations of green teas from the three different growing areas. variations of theanine, isoleucin ... | 2010 | 20828156 |
| why the xanthine derivatives are used to study of p-glycoprotein-mediated multidrug resistance in l1210/vcr line cells. | there is generally well known that various xanthines occur frequently in natural products, e.g. black coffee, black tea, green tea, natural dyes etc. xanthine molecules are good tolerated and metabolised by organisms. moreover, natural xanthines and/or sythesized xanthines may recall a lot positive affects (hemorheologic properties, anti-inflammatory properties, tracheal smooth muscle relaxant, positive chronotropic and central nervous system-stimulating, etc.) and may even induce a quantity of ... | 2010 | 20817945 |
| genoprotective effects of green tea (camellia sinensis) in human subjects: results of a controlled supplementation trial. | green tea is rich in polyphenolic antioxidants and has widely reported but largely unsubstantiated health benefits. in the present study, genoprotective effects of two types of green tea were studied both in an in vitro and in a human supplementation trial. for the in vitro study, human lymphocytes were pre-incubated in tea (0·005-0·1 %, w/v), washed and subjected to oxidant challenge induced by h2o2. in a placebo-controlled, cross-over supplementation study, eighteen healthy volunteers took 2 x ... | 2011 | 20807462 |
| effect of different doses of un-fractionated green & black tea extracts on thyroid physiology. | tea is a rich source of polyphenolic flavonoids including catechins, which are thought to contribute to the health benefits of it. flavonoids have been reported to have antithyroid and goitrogenic effect. the purpose of this study was to evaluate whether high doses of green and black tea have a harmful effect on thyroid physiology. un-fractionated green and black tea extracts were administered orally to male rats for 30 days at doses of 1.25 g%, 2.5 g% and 5.0 g%. the results showed that green t ... | 2010 | 20801949 |
| cytotoxicity of coffee in human intestinal cells in vitro and its inhibition by peroxidase. | the cytotoxic effects of dried preparations of nine different beverages, including alcoholic drinks, on human embryonic intestinal cells in vitro and the cytoprotective effects of several enzymes were examined. instant coffee and green tea were the most cytotoxic beverages (id(50) value 0.016 ml equivalents/ml). peroxidase (0.015 units/ml) completely nullified the cytotoxic effects of instant coffee, green tea and black tea; catalase had a less protective effect. in contrast, superoxide dismutas ... | 1992 | 20732140 |
| in vitro bioconversion of polyphenols from black tea and red wine/grape juice by human intestinal microbiota displays strong interindividual variability. | dietary polyphenols in tea and wine have been associated with beneficial health effects. after ingestion, most polyphenols are metabolized by the colonic microbiota. the current study aimed at exploring the interindividual variation of gut microbial polyphenol bioconversion from 10 healthy human subjects. in vitro fecal batch fermentations simulating conditions in the distal colon were performed using polyphenols from black tea and a mixture of red wine and grape juice. microbial bioconversion w ... | 2010 | 20726519 |
| white and green teas (camellia sinensis var. sinensis): variation in phenolic, methylxanthine, and antioxidant profiles. | recent investigations have associated white teas with anti-carcinogenic, immune-boosting, and antioxidative properties that may impact human health in a manner comparable to green teas. an in-depth chemical analysis of white tea types was conducted to quantify polyphenols and antioxidant potential of 8 commercially available white teas, and compare them to green tea. extraction and hplc protocols were optimized and validated for the quantification of 9 phenolic and 3 methylxanthine compounds to ... | 2010 | 20722909 |
| a novel dietary supplement containing multiple phytochemicals and vitamins elevates hepatorenal and cardiac antioxidant enzymes in the absence of significant serum chemistry and genomic changes. | a novel dietary supplement composed of three well-known phytochemicals, namely, salvia officinalis (sage) extract, camellia sinensis (oolong tea) extract, and paullinia cupana (guarana) extract, and two prominent vitamins (thiamine and niacin) was designed to provide nutritional support by enhancing metabolism and maintaining healthy weight and energy. the present study evaluated the safety of this dietary supplement (stg; s=sage; t=tea; g=guarana) and assessed changes in target organ antioxidan ... | 2010 | 20716937 |
| evaluation of the anti-ulcer activity of nr-anx-c (a polyherbal formulation) in aspirin & pyloric ligature induced gastric ulcers in albino rats. | the aetiology of gastric ulcers is not completely understood and continuous use of anti-ulcer agents leads to many side effects. in this study we evaluated the anti-ulcer efficacy of a polyherbal formulation with potent antioxidant activity in aspirin and pyloric ligature induced gastric ulcers in rats. | 2010 | 20716823 |
| comparison of multivariate preprocessing techniques as applied to electronic tongue based pattern classification for black tea. | in an electronic tongue, preprocessing on raw data precedes pattern analysis and choice of the appropriate preprocessing technique is crucial for the performance of the pattern classifier. while attempting to classify different grades of black tea using a voltammetric electronic tongue, different preprocessing techniques have been explored and a comparison of their performances is presented in this paper. the preprocessing techniques are compared first by a quantitative measurement of separabili ... | 2010 | 20708109 |
| which plant for which skin disease? part 2: dermatophytes, chronic venous insufficiency, photoprotection, actinic keratoses, vitiligo, hair loss, cosmetic indications. | this paper continues our review of scientifically evaluated plant extracts in dermatology. after plants effective against dermatophytes, botanicals with anti-edema effects in chronic venous insufficiency are discussed. there is good evidence from randomized clinical studies that plant extracts from grape vine leaves (vitis vinifera), horse chestnut (aesculus hippocastanum), sea pine (pinus maritima) and butcher's broom (ruscus aculeatus) can reduce edema in chronic venous insufficiency. plant ex ... | 2010 | 20707877 |
| application of phase-trafficking methods to natural products research. | a novel simultaneous phase-trafficking approach using spatially separated solid-supported reagents for rapid separation of neutral, basic, and acidic compounds from organic plant extracts with minimum labor is reported. acidic and basic ion-exchange resins were physically separated into individual sacks ("tea bags") for trapping basic and acidic compounds, respectively, leaving behind in solution neutral components of the natural mixtures. trapped compounds were then recovered from solid phase b ... | 2010 | 20704309 |
| impact of nitrogen supply on carbon/nitrogen allocation: a case study on amino acids and catechins in green tea [camellia sinensis (l.) o. kuntze] plants. | the concentrations of free amino acids (aa) and polyphenols (pp) are important determinants of green tea quality. levels of aa and pp are governed interactively by nitrogen (n) supply and carbon (c) status, so the impact of c/n allocation on green tea quality was investigated in saplings cultivated hydroponically with 0.3, 0.75, 1.5 or 4.5 mmol l(-1) n. activities of glutamine synthetase (gs), phenylalanine ammonia lyase (pal), and phosphoenolpyruvate carboxylase (pepc) were determined, as were ... | 2010 | 20701695 |
| hypotriacylglycerolemic and antiobesity properties of a new fermented tea product obtained by tea-rolling processing of third-crop green tea (camellia sinensis) leaves and loquat (eriobotrya japonica) leaves. | we manufactured a new fermented tea by tea-rolling processing of third-crop green tea (camellia sinensis) leaves and loquat (eriobotrya japonica) leaves. the mixed fermented tea extract inhibited pancreatic lipase activity in vitro, and effectively suppressed postprandial hypertriacylglycerolemia in rats. rats fed a diet containing 1% freeze-dried fermented tea extract for 4 weeks had a significantly lower liver triacylglycerol concentration and white adipose tissue weight than those fed the con ... | 2010 | 20699580 |
| computational identification of mirnas and their target genes from expressed sequence tags of tea (camellia sinensis). | micrornas (mirnas) are a newly identified class of small non-protein-coding post-transcriptional regulatory rna in both plants and animals. the use of computational homology based search for expressed sequence tags (ests) with the ambros empirical formula and other structural feature criteria filter is a suitable combination towards the discovery and isolation of conserved mirnas from tea and other plant species whose genomes are not yet sequenced. in the present study, we blasted the database o ... | 2010 | 20691396 |
| risk factors for renal cell cancer in a japanese population. | the incidence of renal cell cancer has been increasing worldwide. although the incidence of renal cell cancer in japan is lower than the rates in the other industrialized countries, there is no doubt that it is increasing. in this paper, we would like to introduce the result of our studies, which evaluate the risk factors for renal cell cancer in japan. hypertension, diabetes mellitus, kidney diseases, fondness for fatty food and black tea showed an increased risk of renal cell carcinoma while a ... | 2009 | 20689612 |
| [sugary drinks and glycemia]. | obesity prevalence is increasing all over the world. most affected are people changing from a traditional lifestyle to an environment with both availability of high energy diet and less physical activity. glycemic index (gi) is a measure of dietary glycemic carbohydrates, representing their ability to raise blood glucose concentrations. it refers to the postprandial blood glucose response expressed as a percentage of the response to a reference food (glucose or white bread) containing the same c ... | 2010 | 20687984 |
| black-tea polyphenols decrease micellar solubility of cholesterol in vitro and intestinal absorption of cholesterol in rats. | administration of black-tea polyphenols (btp) simultaneously reduced lymphatic recovery of both (3)h-cholesterol and (14)c-trioleoylglycerol in rats that were cannulated in the thoracic duct. btp decreased the in vitro micellar solubility of cholesterol in a dose-dependent manner. when purified theaflavins, which are components of btp, were used, theaflavin-monogallates (tfmgs), theaflavin-3-gallate (tf3g), and theaflavin-3'-gallate (tf3'g) were effective in eliminating cholesterol from bile sal ... | 2010 | 20681647 |
| sugar compositions, α-glucosidase inhibitory and amylase inhibitory activities of polysaccharides from leaves and flowers of camellia sinensis obtained by different extraction methods. | the sugar compositions, α-glucosidase inhibitory and α-amylase inhibitory activities of polysaccharides from leaves and flowers of green tea (camellia sinensis) obtained by hot water extraction (hwe), boiled water extraction (bwe) and enzymatic extraction (ee) were investigated. the yields, sugar contents and monosaccharide compositions of tea leaves polysaccharides (tlps) and tea flower polysaccharides (tfps) were all significantly affected by extraction methods. the contents of acidic polysacc ... | 2010 | 20678520 |
| effects of the black tea polyphenol theaflavin-2 on apoptotic and inflammatory pathways in vitro and in vivo. | scope: theaflavin-2 (tf-2), a major component of black tea extract, induces apoptosis of human colon cancer cells and suppresses serum-induced cyclooxygenase-2 (cox-2) expression 1. here, we explored the mechanisms for activation of apoptosis, evaluated the impact on inflammatory genes in a broader panel of cells and tested whether topical anti-inflammatory effects could be observed in vivo. methods and results: tf-2 triggered apoptosis in five other transformed cancer cell lines, inducing cell ... | 2011 | 20669245 |
| regular daily intake of black tea improves oxidative stress biomarkers and decreases serum c-reactive protein levels in type 2 diabetic patients. | this study was undertaken to evaluate the possible effects of different daily doses of black tea intake on certain oxidative stress, inflammatory and metabolic biomarkers in patients with type 2 diabetes mellitus (t2dm). | 2010 | 20668372 |
| prokaryotic expression and purification of camellia sinensis polyphenol oxidase. | polyphenol oxidase (ppo) causes the postharvest loss of fruits and vegetables but is also a key factor in the quality development of tea. however, there are no reports on engineered active plant ppo purified from prokaryotic cells. | 2010 | 20661922 |
| green tea extract-patents and diversity of uses. | green tea is one of the most consumed beverages in the world. presently, camellia sinensis has become a source not only for the development of several food extracts but also nutraceutical, cosmetic and medicinal purposes. the technology developed to produce these extracts aims to improve the organoleptic characteristics of the products as taste and smell, and their shelf life. but it also searches to demonstrate some medicinal attributes like antioxidant, anti-aging, anti-tumor and anti-viral ac ... | 2009 | 20653541 |
| recent patents on camellia sinensis: source of health promoting compounds. | in recent years, the scientific community, food industry, consumers and media have revealed a growing interest regarding the potential benefits of tea consumption for human health. several studies indicate that phenolic compounds, especially flavan-3-ols (catechins), are the main components responsible for the medicinal effects of this beverage due to their recognized antioxidant properties. antioxidants are ascribed to reduce cells and biomolecules oxidative damage caused by reactive oxygen/nit ... | 2009 | 20653539 |
| development of cell culture techniques for assessment of the toxicity of plant products. | plant products consumed by humans contain a wide variety of both beneficial and toxic compounds. studies have been undertaken to explore the utility of cell culture techniques in testing plant products for toxicity and antitoxicity. preliminary results are reported on the cytotoxic effects of aqueous and methanol extracts of a range of conventional and herb teas and a variety of vegetables. the teas were tested in primary cultures of rat hepatocytes, using lactate dehydrogenase release and inhib ... | 1996 | 20650184 |
| home management of acute diarrhoea in czech children. | the aim of the study was to investigate home management of childhood acute diarrhoea. | 2010 | 20639709 |
| determination of antioxidants by a novel on-line hplc-cupric reducing antioxidant capacity (cuprac) assay with post-column detection. | a novel on-line hplc-cupric reducing antioxidant capacity (cuprac) method was developed for the selective determination of polyphenols (flavonoids, simple phenolic and hydroxycinnamic acids) in complex plant matrices. the method combines chromatographic separation, constituent analysis, and post-column identification of antioxidants in plant extracts. the separation of polyphenols was performed on a c18 column using gradient elution with two different mobile phase solutions, i.e., meoh and 0.2% ... | 2010 | 20638503 |
| determination of polycyclic aromatic hydrocarbons in food samples by automated on-line in-tube solid-phase microextraction coupled with high-performance liquid chromatography-fluorescence detection. | a simple and sensitive automated method, consisting of in-tube solid-phase microextraction (spme) coupled with high-performance liquid chromatography-fluorescence detection (hplc-fld), was developed for the determination of 15 polycyclic aromatic hydrocarbons (pahs) in food samples. pahs were separated within 15 min by hplc using a zorbax eclipse pah column with a water/acetonitrile gradient elution program as the mobile phase. the optimum in-tube spme conditions were 20 draw/eject cycles of 40 ... | 2010 | 20637468 |
| prevention of diet-induced obesity by dietary black tea polyphenols extract in vitro and in vivo. | the effects of certain tea components on the prevention of obesity in humans have recently been reported, although it is still unclear whether black tea consumption is beneficial. we obtained black tea extract (btpe) consisting of polyphenols specific to black tea, and from it, prepared a polymerized polyphenol fraction (btp). the effectiveness of oral administration of the btpe was examined in in vitro and in vivo experiments. | 2011 | 20627658 |
| potential mechanisms of hypocholesterolaemic effect of thai spices/dietary extracts. | several thai spices/dietary ingredients were previously shown to have hypocholesterolaemic effects. these studies were mostly conducted in animal models in which the mechanisms of action were not yet well-established. therefore, this study aimed to investigate the potential mechanism of hypocholesterolaemic action of 12 selected plants, namely hibiscus sabdariffa l., moringa oleifera lam., cucurbita moschata duchesne, ananas comosus (l.) merr., zingiber officinale, morus alba l., camellia sinens ... | 2011 | 20623425 |
| camellisins a-c, three new triterpenoids from the roots of camellia sinensis. | eighteen compounds, including three new triterpenoids, camellisins a-c (1-3), were isolated from the roots of camellia sinensis. their structures were determined on the basis of detailed spectroscopic analysis. | 2010 | 20606341 |
| green tea minimally affects biomarkers of inflammation in obese subjects with metabolic syndrome. | green tea (camellia sinensis) has shown to exert cardioprotective benefits in observational studies. the objective of this clinical trial was to assess the effects of green tea on features of metabolic syndrome and inflammation in obese subjects. | 2011 | 20605696 |
| coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and nrf2 in liver and stomach. | coffee is one of the most widely consumed beverages worldwide. epidemiologic data indicate that coffee consumption protects against the progression of chronic liver disease and development of hepatocellular carcinoma and diabetes, but the mechanisms are not clear. udp glucuronosyltransferases (ugt1a) are proteins with indirect antioxidant, cytoprotective, and genoprotective capabilities; we examined ugt1a regulation in response to coffee in cultured cells and mice. | 2010 | 20600030 |
| preventive effects of black tea theaflavins against mouse type iv allergy. | tea (camellia sinensis l.), one of the most popular beverages, contains various beneficial constituents. we investigated the preventive effects of black tea theaflavins, theaflavin-3-gallate (3-tf) and theaflavin-3,3'-digallate (tfdg), on oxazolone-induced type iv allergy in male icr mice. | 2010 | 20597096 |
| ancient genome duplications during the evolution of kiwifruit (actinidia) and related ericales. | to assess the number and phylogenetic distribution of large-scale genome duplications in the ancestry of actinidia, publicly available expressed sequenced tags (ests) for members of the actinidiaceae and related ericales, including tea (camellia sinensis), were analysed. | 2010 | 20576738 |
| correlation of dispersibility of proteins with that of selenium in teas. | selenium-enriched tea was suggested as a possible source of supplemental se. the result of this study indicates that it is not practicable to make selenium-enriched tea as a beverage like traditional green tea or black tea for the supplementation of selenium in human diet. the selenium dispersibilities of fresh tea leaves, green tea, and black tea highly correlated with those of protein (r (2) = 0.998). the high protein dispersibility (85.0%) of fresh tea leaves in water solution was accompanied ... | 2010 | 20567933 |
| the antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention. | green tea (camellia sinensis) is rich in catechins, of which (-)-epigallocatechin-3-gallate (egcg) is the most abundant. studies in animal models of carcinogenesis have shown that green tea and egcg can inhibit tumorigenesis during the initiation, promotion and progression stages. many potential mechanisms have been proposed including both antioxidant and pro-oxidant effects, but questions remain regarding the relevance of these mechanisms to cancer prevention. in the present review, we will dis ... | 2010 | 20558130 |
| diversity among various forms of catechins and its synthesizing enzyme (phenylalanine ammonia lyase) in relation to quality of black tea (camellia spp.). | quality of tea depends on the cultivar and climatic conditions. biochemical pathways within the plant and climatic factors can result in noticeable changes in chemical composition, which determine the quality of tea. black tea quality attributes are influenced by various forms of catechins, namely gallated, non-gallated, dihydroxylated and trihydroxylated catechins and their ratios. hence the variations in grouped catechins and their synthesizing enzyme in relation to quality of south indian bla ... | 2010 | 20549808 |
| lead contamination in different varieties of tea plant (camellia sinensis l.) and factors affecting lead bioavailability. | there has been increasing concern in recent years about the concentration of lead (pb) in tea. however, little research has been done to address questions concerning the distribution of pb in different varieties of tea plant and the differences among tea plant varieties in their uptake and accumulation of pb from the soil. therefore the aim of this study was to investigate the accumulation of pb in different tea plant varieties and the factors affecting pb bioavailability. | 2010 | 20549803 |
| enhancement of the phagocytic activity of macrophage-like cells with a crude polysaccharide derived from green tea (camellia sinensis) extract. | to identify the immunostimulants included in green tea extract, we investigated a crude tea polysaccharide related to increases in phagocytic activity using macrophage-like cells, and found that the crude tea polysaccharide from immature tea leaves included many rnas as compared with that from mature tea leaves. furthermore, the crude tea polysaccharide increased phagocytosis through toll-like receptor 7. | 2010 | 20530892 |
| black tea polyphenol (theaflavin) downregulates mmp-2 in human melanoma cell line a375 by involving multiple regulatory molecules. | the tumor-inhibiting property of black tea polyphenol, theaflavin, is well documented. matrix metalloproteinases (mmps) play a pivotal role in tumor invasion through degradation of extracellular matrix (ecm). in the present study, we observed the effect of theaflavin on mmp-2, which is upregulated in most tumor types, and its regulatory molecules, in human melanoma cell line, a375. the treatment of theaflavin downregulated the gelatinolytic activity, mrna and protein expression of mmp-2. it redu ... | 2010 | 20528747 |
| botanicals in dermatology: an evidence-based review. | botanical extracts and single compounds are increasingly used in cosmetics but also in over-the-counter drugs and food supplements. the focus of the present review is on controlled clinical trials with botanicals in the treatment of acne, inflammatory skin diseases, skin infections, uv-induced skin damage, skin cancer, alopecia, vitiligo, and wounds. studies with botanical cosmetics and drugs are discussed, as well as studies with botanical food supplements. experimental research on botanicals w ... | 2010 | 20509719 |
| synergistic effects of tea polyphenols and ascorbic acid on human lung adenocarcinoma spc-a-1 cells. | tea polyphenols have been shown to have anticancer activity in many studies. in the present study, we investigated effects of theaflavin-3-3'-digallate (tf(3)), one of the major theaflavin monomers in black tea, in combination with ascorbic acid (aa), a reducing agent, and (-)-epigallocatechin-3-gallate (egcg), the main polyphenol presented in green tea, in combination with aa on cellular viability and cell cycles of the human lung adenocarcinoma spc-a-1 cells. the 3-(4,5-dimethylthiazol-2-yl)-2 ... | 2010 | 20506578 |
| green and black tea inhibit cytokine-induced il-8 production and secretion in ags gastric cancer cells via inhibition of nf-κb activity. | consumption of tea is associated with a reduced risk for several gastrointestinal cancers. inflammatory processes, such as secretion of il-8 from the gastric epithelium in response to chronic chemokine or antigen exposure, serve both as a chemoattractant for white blood cells and a prerequisite for gastric carcinogenesis. in this study, the gastric adenocarcinoma cell line ags was used to investigate the effect of green tea extract, black tea extract, and epigallocatechin gallate (egcg), the mos ... | 2010 | 20506079 |
| evaluation of fungal burden and aflatoxin presence in packed medicinal plants treated by gamma radiation. | this study was developed to evaluate the fungal burden, toxigenic molds, and mycotoxin contamination and to verify the effects of gamma radiation in four kinds of medicinal plants stored before and after 30 days of irradiation treatment. eighty samples of medicinal plants (peumus boldus, camellia sinensis, maytenus ilicifolia, and cassia angustifolia) purchased from drugstores, wholesale, and open-air markets in são paulo city, brazil, were analyzed. the samples were treated using a (60)co gamma ... | 2010 | 20501045 |