Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| genesippr: a rapid whole-genome approach for the identification and characterization of foodborne pathogens such as priority shiga toxigenic escherichia coli. | the timely identification and characterization of foodborne bacteria for risk assessment purposes is a key operation in outbreak investigations. current methods require several days and/or provide low-resolution characterization. here we describe a whole-genome-sequencing (wgs) approach (genesippr) enabling same-day identification of colony isolates recovered from investigative food samples. the identification of colonies of priority shiga-toxigenic escherichia coli (stec) (i.e., serogroups o26, ... | 2015 | 25860693 |
| an unconventional anaerobic membrane protein production system based on wolinella succinogenes. | in cases where membrane protein production attempts in more conventional escherichia coli-based systems have failed, a solution is to resort to a system based on the nonpathogenic epsilon-proteobacterium wolinella succinogenes. this approach has been demonstrated to be successful for structural and mechanistic analyses not only for homologous production of w. succinogenes membrane proteins but also for the heterologous production of membrane protein complexes from the human pathogens helicobacte ... | 2015 | 25857779 |
| antibiotic-resistant bacteria: prevalence in food and inactivation by food-compatible compounds and plant extracts. | foodborne antibiotic-resistant pathogenic bacteria such as campylobacter jejuni, bacillus cereus, clostridium perfringens, escherichia coli, salmonella enterica, staphylococcus aureus, vibrio cholerae, and vibrio parahemolyticus can adversely affect animal and human health, but a better understanding of the factors involved in their pathogenesis is needed. to help meet this need, this overview surveys and interprets much of our current knowledge of antibiotic (multidrug)-resistant bacteria in th ... | 2015 | 25856120 |
| predictors of rational management of diarrhea in an endemic setting: observation from india. | decades after the establishment of clear guidelines for management, mostly due to irrational approach, diarrhea is still a major concern in the developing world, including india. the scenario is even worse in urban slums owing to poor health-seeking and socio-environmental vulnerability. determining the distribution of rational diarrhea management by practitioners and identification of its important predictors seemed urgent to minimize the potential for antibiotic resistance, diarrhea-related mo ... | 2015 | 25849617 |
| expression of stress-related proteins in sediminibacterium sp. growing under planktonic conditions. | aggregation is a common trait of bacteria in natural and engineered biological systems. microbial aggregates, such as flocs, granules, and biofilms, are spatially heterogeneous environments. it is generally observed that by growing under aggregated conditions bacteria respond and adapt to environmental stress better than free-swimming bacteria of the same species. we performed a proteomic analysis of a strain of sediminibacterium, isolated from activated sludge, which grew planktonically in dilu ... | 2015 | 25847231 |
| a five-year study on prevalence and antimicrobial resistance of campylobacter from poultry carcasses in poland. | during 2009-2013 a total of 2114 swab samples collected from broiler carcasses in all 16 voivodeships (administrative districts) of poland were examined for the presence of campylobacter jejuni and campylobacter coli. the antimicrobial resistance of the isolates to ciprofloxacin, tetracycline and erythromycin using the mic method was also tested. it was found that 1151 (54.4%) carcasses were contaminated with campylobacter, with 50% of c. jejuni and c. coli species isolated from positive samples ... | 2015 | 25846926 |
| the combined efficacy of carvacrol and modified atmosphere packaging on the survival of salmonella, campylobacter jejuni and lactic acid bacteria on turkey breast cutlets. | the primary objective of this study was to determine the efficacy of carvacrol in combination with modified atmosphere packaging (map) in reducing salmonella on turkey breast cutlets stored at 4 °c. in experiment i, carvacrol (0.5, 1, and 2% v/v) was applied as surface treatment and samples were stored under aerobic condition or as surface and dip treatments followed by storage in an environment of 100% carbon dioxide. the findings of the experiment i revealed the synergistic activity of carvacr ... | 2015 | 25846923 |
| extracellular zinc induces phosphoethanolamine addition to pseudomonas aeruginosa lipid a via the colrs two-component system. | gram-negative bacteria survive harmful environmental stressors by modifying their outer membrane. much of this protection is afforded upon remodeling of the lipid a region of the major surface molecule lipopolysaccharide (lps). for example, the addition of cationic substituents, such as 4-amino-4-deoxy-l-arabinose (l-ara4n) and phosphoehthanolamine (petn) at the lipid a phosphate groups, is often induced in response to specific environmental flux stabilizing the outer membrane. the work herein r ... | 2015 | 25846400 |
| virulence characterization of campylobacter jejuni isolated from resident wild birds in tokachi area, japan. | the prevalence of campylobacter jejuni in wild birds is a potential hazard for human and animal health. the aim of this study was to establish the prevalence of c. jejuni in wild birds in tokachi area, hokkaido, japan and investigate their virulence in vitro. in total, 173 cloacal swabs from individual wild birds were collected for the detection of campylobacter spp. thirty four samples (19.7%) were positive for campylobacter of which 94.1% (32/34 samples) were c. jejuni. additionally, one c. co ... | 2015 | 25843040 |
| interactions between human norovirus surrogates and acanthamoeba spp. | human noroviruses (hunovs) are the most common cause of food-borne disease outbreaks, as well as virus-related waterborne disease outbreaks in the united states. here, we hypothesize that common free-living amoebae (fla)-ubiquitous in the environment, known to interact with pathogens, and frequently isolated from water and fresh produce-could potentially act as reservoirs of hunov and facilitate the environmental transmission of hunovs. to investigate fla as reservoirs for hunov, the interaction ... | 2015 | 25841006 |
| dnak protein alleviates toxicity induced by citrate-coated gold nanoparticles in escherichia coli. | a number of previously reported studies suggest that synthetic gold nanoparticles (aunps) are capable of stabilising proteins against heat stress in vitro. however, it remains to be understood if aunps confer stability to proteins against cellular stress in vivo. heat shock proteins (hsps) are conserved molecules whose main role is to facilitate folding of other proteins (chaperone function). hsp70 (called dnak in prokaryotes) is one of the most prominent molecular chaperones. since gold nanopar ... | 2015 | 25837593 |
| microbiological diversity and prevalence of spoilage and pathogenic bacteria in commercial fermented alcoholic beverages (beer, fruit wine, refined rice wine, and yakju). | the present study examined 469 commercially available fermented alcoholic beverages (fabs), including beer (draft, microbrewed, and pasteurized), fruit wine (grape and others), refined rice wine, and yakju (raw and pasteurized). samples were screened for escherichia coli and eight foodborne pathogens (bacillus cereus, campylobacter jejuni, clostridium perfringens, escherichia coli o157:h7, listeria monocytogenes, salmonella spp., staphylococcus aureus, and yersinia enterocolitica), and the aerob ... | 2015 | 25836410 |
| effect of oxygen stress on growth and survival of clostridium perfringens, campylobacter jejuni, and listeria monocytogenes under different storage conditions. | this study investigated the growth and survival of three foodborne pathogens (clostridium perfringens, campylobacter jejuni, and listeria monocytogenes) in beef (7% fat) and nutrient broth under different oxygen levels. samples were tested under anoxic (<0.5%), microoxic (6 to 8%), and oxic (20%) conditions during storage at 7 °c for 14 days and at 22 °c for 5 days. two initial inoculum concentrations were used (1 and 2 log cfu per g of beef or per ml of broth). the results show that c. perfring ... | 2015 | 25836393 |
| autism spectrum disorders and intestinal microbiota. | through extensive microbial-mammalian co-metabolism, the intestinal microbiota have evolved to exert a marked influence on health and disease via gut-brain-microbiota interactions. in this addendum, we summarize the findings of our recent study on the fecal microbiota and metabolomes of children with pervasive developmental disorder-not otherwise specified (pdd-nos) or autism (ad) compared with healthy children (hc). children with pdd-nos or ad have altered fecal microbiota and metabolomes (incl ... | 2015 | 25835343 |
| milk bioactives may manipulate microbes to mediate parent-offspring conflict. | among mammals, milk constituents directly influence the ecology of the infant's commensal microbiota. the immunological and nutritional impacts of breast milk and microbiota are increasingly well understood; less clear are the consequences for infant behavior. here, we propose that interactions among bioactives in mother's milk and microbes in the infant gut contribute to infant behavioral phenotype and, in part, have the potential to mediate parent-offspring conflict. we hypothesize that infant ... | 2015 | 25835022 |
| antimicrobial peptides: current and potential applications in biomedical therapies. | 2015 | 25834815 | |
| increased efficiency of campylobacter jejuni n-oligosaccharyltransferase pglb by structure-guided engineering. | conjugate vaccines belong to the most efficient preventive measures against life-threatening bacterial infections. functional expression of n-oligosaccharyltransferase (n-ost) pglb of campylobacter jejuni in escherichia coli enables a simplified production of glycoconjugate vaccines in prokaryotic cells. polysaccharide antigens of pathogenic bacteria can be covalently coupled to immunogenic acceptor proteins bearing engineered glycosylation sites. transfer efficiency of pglbcj is low for certain ... | 2015 | 25833378 |
| regulation of bacterial virulence by csr (rsm) systems. | most bacterial pathogens have the remarkable ability to flourish in the external environment and in specialized host niches. this ability requires their metabolism, physiology, and virulence factors to be responsive to changes in their surroundings. it is no surprise that the underlying genetic circuitry that supports this adaptability is multilayered and exceedingly complex. studies over the past 2 decades have established that the csra/rsma proteins, global regulators of posttranscriptional ge ... | 2015 | 25833324 |
| first case report of campylobacter volucris bacteremia in an immunocompromised patient. | we report a case of campylobacter volucris bacteremia in an immunocompromised patient with polycythemia vera and alcoholic liver cirrhosis. to our knowledge, this is the first case report in which this organism has been isolated from a human clinical specimen. | 2015 | 25832303 |
| characterization of an α-l-fucosidase from the periodontal pathogen tannerella forsythia. | the periodontal pathogen tannerella forsythia expresses several glycosidases which are linked to specific growth requirements and are involved in the invasion of host tissues. α-l-fucosyl residues are exposed on various host glycoconjugates and, thus, the α-l-fucosidases predicted in the t. forsythia atcc 43037 genome could potentially serve roles in host-pathogen interactions. we describe the molecular cloning and characterization of the putative fucosidase tffuc1 (encoded by the bfo_2737 = tff ... | 2015 | 25831954 |
| campylobacter jejuni infection and ige sensitization in up to 2-year-old infants. | the "hygiene hypothesis" addresses the correlation between the occurrence of atopy and the frequency of infections in the earliest age, explaining an increase in the incidence of atopic diseases by living in good, infection-free, hygienic conditions. the aim of our study was to determine the conection between atopy and camplobacter infection, and to analyze the association between serum concentrations of total ige and campyobacter infection in relation to atopy in children up to two years. | 2015 | 25831906 |
| insights into campylobacter jejuni colonization of the mammalian intestinal tract using a novel mouse model of infection. | a lack of relevant disease models for campylobacter jejuni has long been an obstacle to research into this common enteric pathogen. we recently published that mice deficient in single igg interleukin-1 related receptor (sigirr), a repressor of myd88-dependent innate immune signaling, were highly susceptible to enteric infection by murine bacterial pathogens. subsequently, we successfully employed these mice as an animal model for the human pathogen c. jejuni and gained substantial new insights i ... | 2015 | 25831043 |
| antibiotic resistance modulation and modes of action of (-)-α-pinene in campylobacter jejuni. | the aim of the study was to investigate the mode of action of (-)-α-pinene in terms of its modulation of antibiotic resistance in campylobacter jejuni. broth microdilution and ethidium bromide accumulation assays were used to evaluate the (-)-α-pinene antimicrobial activity, modulation of antimicrobial resistance, and inhibition of antimicrobial efflux. the target antimicrobial efflux systems were identified using an insertion mutagenesis approach, and c. jejuni adaptation to (-)-α-pinene was ev ... | 2015 | 25830640 |
| the gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. | the gut-brain axis (gba) consists of bidirectional communication between the central and the enteric nervous system, linking emotional and cognitive centers of the brain with peripheral intestinal functions. recent advances in research have described the importance of gut microbiota in influencing these interactions. this interaction between microbiota and gba appears to be bidirectional, namely through signaling from gut-microbiota to brain and from brain to gut-microbiota by means of neural, e ... | 2015 | 25830558 |
| antimicrobial activity of turmeric extract and its potential use in food industry. | the present study investigates the antimicrobial and preservative potentials of turmeric extracts for food industry. turmeric extracts prepared in n-hexane, water, chloroform and ethanol were applied to meals as preservatives and antibacterial agent. the samples were assessed microbiologically (total bacterial, total fungal and total coliform counts) and organoleptically (color, odor, taste) at day zero and after 15 days intervals. meals autoclaved for shorter time (5 min) and treated with combi ... | 2013 | 25829609 |
| antimicrobial activity of turmeric extract and its potential use in food industry. | the present study investigates the antimicrobial and preservative potentials of turmeric extracts for food industry. turmeric extracts prepared in n-hexane, water, chloroform and ethanol were applied to meals as preservatives and antibacterial agent. the samples were assessed microbiologically (total bacterial, total fungal and total coliform counts) and organoleptically (color, odor, taste) at day zero and after 15 days intervals. meals autoclaved for shorter time (5 min) and treated with combi ... | 2013 | 25829609 |
| enhanced bactericidal effect of enterocin a in combination with thyme essential oils against l. monocytogenes and e. coli o157:h7. | the combined effects of enterocin a with thymus vulgaris essential oils (eos) against listeria monocytogenes and escherichia coli o157:h7 were investigated in vitro by enumeration of surviving populations of testing pathogens and minimal inhibitory concentration (mic) determination. enterocin a was purified to homogeneity by rp-hplc from the culture fluid of enterococcus strain and thyme eos were extracted from local thymus vulgaris plants. the major constituent of thyme eos oils determined by g ... | 2013 | 25829595 |
| enhanced bactericidal effect of enterocin a in combination with thyme essential oils against l. monocytogenes and e. coli o157:h7. | the combined effects of enterocin a with thymus vulgaris essential oils (eos) against listeria monocytogenes and escherichia coli o157:h7 were investigated in vitro by enumeration of surviving populations of testing pathogens and minimal inhibitory concentration (mic) determination. enterocin a was purified to homogeneity by rp-hplc from the culture fluid of enterococcus strain and thyme eos were extracted from local thymus vulgaris plants. the major constituent of thyme eos oils determined by g ... | 2013 | 25829595 |
| basal body structures differentially affect transcription of rpon- and flia-dependent flagellar genes in helicobacter pylori. | flagellar biogenesis in helicobacter pylori is regulated by a transcriptional hierarchy governed by three sigma factors, rpod (σ(80)), rpon (σ(54)), and flia (σ(28)), that temporally coordinates gene expression with the assembly of the flagellum. previous studies showed that loss of flagellar protein export apparatus components inhibits transcription of flagellar genes. the flgs/flgr two-component system activates transcription of rpon-dependent genes though an unknown mechanism. to understand b ... | 2015 | 25825427 |
| increased intracellular calcium level and impaired nutrient absorption are important pathogenicity traits in the chicken intestinal epithelium during campylobacter jejuni colonization. | although a high number of chickens carry campylobacter jejuni, the mechanistic action of colonization in the intestine is still poorly understood. the current study was therefore designed to investigate the effects of c. jejuni on glucose uptake, amino acids availability in digesta, and intracellular calcium [ca(2+)]i signaling in the intestines of broiler chickens. for this, we compared: control birds (n = 60) and c. jejuni-infected birds (n = 60; infected orally with 1 × 10(8) cfu of c. jejuni ... | 2015 | 25825050 |
| cytochrome c biogenesis in campylobacter jejuni requires cytochrome c6 (ccca; cj1153) to maintain apocytochrome cysteine thiols in a reduced state for haem attachment. | the microaerophilic food-borne pathogen campylobacter jejuni uses complex cytochrome-rich respiratory chains for growth and host colonisation. cytochrome c biogenesis requires haem ligation to reduced apocytochrome cysteines, catalysed by the cytochrome c synthase, ccsba. while ccsba could not be deleted, we showed that the thiol reductase dsbd and the ccsx homologue cj1207 are involved in, but not essential for, cytochromes c biogenesis. mutant phenotypic analyses and biochemical studies with p ... | 2015 | 25825009 |
| staphylococcus aureus mnhf mediates cholate efflux and facilitates survival under human colonic conditions. | resistance to the innate defenses of the intestine is crucial for the survival and carriage of staphylococcus aureus, a common colonizer of the human gut. bile salts produced by the liver and secreted into the intestines are one such group of molecules with potent antimicrobial activity. the mechanisms by which s. aureus is able to resist such defenses in order to colonize and survive in the human gut are unknown. here we show that mnhf confers resistance to bile salts, which can be abrogated by ... | 2015 | 25824834 |
| consensus paper: neuroimmune mechanisms of cerebellar ataxias. | in the last few years, a lot of publications suggested that disabling cerebellar ataxias may develop through immune-mediated mechanisms. in this consensus paper, we discuss the clinical features of the main described immune-mediated cerebellar ataxias and address their presumed pathogenesis. immune-mediated cerebellar ataxias include cerebellar ataxia associated with anti-gad antibodies, the cerebellar type of hashimoto's encephalopathy, primary autoimmune cerebellar ataxia, gluten ataxia, mille ... | 2015 | 25823827 |
| consensus paper: neuroimmune mechanisms of cerebellar ataxias. | in the last few years, a lot of publications suggested that disabling cerebellar ataxias may develop through immune-mediated mechanisms. in this consensus paper, we discuss the clinical features of the main described immune-mediated cerebellar ataxias and address their presumed pathogenesis. immune-mediated cerebellar ataxias include cerebellar ataxia associated with anti-gad antibodies, the cerebellar type of hashimoto's encephalopathy, primary autoimmune cerebellar ataxia, gluten ataxia, mille ... | 2015 | 25823827 |
| influence of a non-hospital medical care facility on antimicrobial resistance in wastewater. | the global widespread use of antimicrobials and accompanying increase in resistant bacterial strains is of major public health concern. wastewater systems and wastewater treatment plants are considered a niche for antibiotic resistance genes (args), with diverse microbial communities facilitating arg transfer via mobile genetic element (mge). in contrast to hospital sewage, wastewater from other health care facilities is still poorly investigated. at the instance of a nursing home located in sou ... | 2015 | 25821977 |
| cloning and expression of synthetic genes encoding the broad antimicrobial spectrum bacteriocins srcam 602, or-7, e-760, and l-1077, by recombinant pichia pastoris. | we have evaluated the cloning and functional expression of previously described broad antimicrobial spectrum bacteriocins srcam 602, or-7, e-760, and l-1077, by recombinant pichia pastoris. synthetic genes, matching the codon usage of p. pastoris, were designed from the known mature amino acid sequence of these bacteriocins and cloned into the protein expression vector ppiczαa. the recombinant derived plasmids were linearized and transformed into competent p. pastoris x-33, and the presence of i ... | 2015 | 25821820 |
| microbial contamination of drinking water and human health from community water systems. | a relatively short list of reference viral, bacterial and protozoan pathogens appears adequate to assess microbial risks and inform a system-based management of drinking waters. nonetheless, there are data gaps, e.g. human enteric viruses resulting in endemic infection levels if poorly performing disinfection and/or distribution systems are used, and the risks from fungi. where disinfection is the only treatment and/or filtration is poor, cryptosporidiosis is the most likely enteric disease to b ... | 2015 | 25821716 |
| recreational water and infection: a review of recent findings. | this paper reviews the latest evidence provided by epidemiological studies and quantitative microbial risk assessments (qmras) of infection risk from recreational water use. studies for review were selected following a pubmed search for articles published between january 2010 and april 2014. epidemiological studies show a generally elevated risk of gastrointestinal illness in bathers compared to non-bathers but often no clear association with water quality as measured by faecal indicator bacteri ... | 2015 | 25821715 |
| an update on the transport and metabolism of iron in listeria monocytogenes: the role of proteins involved in pathogenicity. | listeria monocytogenes is a gram-positive bacterium that causes a rare but severe human disease with high mortality rate. the microorganism is widespread in the natural environment where it shows a saprophytic lifestyle. in the human body it infects many different cell types, where it lives intracellularly, however it may also temporarily live extracellularly. the ability to survive and grow in such diverse niches suggests that this bacterium has a wide range of mechanisms for both the acquisiti ... | 2015 | 25820385 |
| an l-fucose operon in the probiotic lactobacillus rhamnosus gg is involved in adaptation to gastrointestinal conditions. | l-fucose is a sugar present in human secretions as part of human milk oligosaccharides, mucins, and other glycoconjugates in the intestinal epithelium. the genome of the probiotic lactobacillus rhamnosus gg (lgg) carries a gene cluster encoding a putative l-fucose permease (fucp), l-fucose catabolic pathway (fuci, fuck, fucu, and fuca), and a transcriptional regulator (fucr). the metabolism of l-fucose in lgg results in 1,2-propanediol production, and their fuci and fucp mutants displayed a seve ... | 2015 | 25819967 |
| antimicrobial activity and stability of weakly acidified chlorous acid water. | the antimicrobial activity of weakly acidified chlorous acid water (wacaw) against staphylococcus aureus, non-pathogenic escherichia coli, enterohemorrhagic e. coli (ehec o157:h7), candida albicans, and spore-forming bacillus and paenibacillus species was evaluated in vitro. the antiviral activity was also examined using feline calicivirus (fcv). diluted wacaw (>100 ppm) effectively reduced the number of non-spore-forming bacteria (>4 log10 cfu reductions) within 5 min. treatment with this sanit ... | 2015 | 25817812 |
| effects of source- versus household contamination of tubewell water on child diarrhea in rural bangladesh: a randomized controlled trial. | shallow tubewells are the primary drinking water source for most rural bangladeshis. fecal contamination has been detected in tubewells, at low concentrations at the source and at higher levels at the point of use. we conducted a randomized controlled trial to assess whether improving the microbiological quality of tubewell drinking water by household water treatment and safe storage would reduce diarrhea in children <2 years in rural bangladesh. | 2015 | 25816342 |
| predominant virulent iba10g2 subtype of cryptosporidium hominis in human isolates in barcelona: a five-year study. | cryptosporidium infection is a worldwide cause of diarrheal disease. to gain insight into the epidemiology of the infection in a certain geographic area, molecular methods are needed to determine the species/genotypes and subtypes. | 2015 | 25816024 |
| the epidemiology and aetiology of diarrhoeal disease in infancy in southern vietnam: a birth cohort study. | previous studies indicate a high burden of diarrhoeal disease in vietnamese children, however longitudinal community-based data on burden and aetiology are limited. the findings from a large, prospective cohort study of diarrhoeal disease in infants in southern vietnam are presented herein. | 2015 | 25813553 |
| inhibition of type vi secretion by an anti-tssm llama nanobody. | the type vi secretion system (t6ss) is a secretion pathway widespread in gram-negative bacteria that targets toxins in both prokaryotic and eukaryotic cells. although most t6sss identified so far are involved in inter-bacterial competition, a few are directly required for full virulence of pathogens. the t6ss comprises 13 core proteins that assemble a large complex structurally and functionally similar to a phage contractile tail structure anchored to the cell envelope by a trans-membrane spanni ... | 2015 | 25811612 |
| mammalian synthetic biology: emerging medical applications. | in this review, we discuss new emerging medical applications of the rapidly evolving field of mammalian synthetic biology. we start with simple mammalian synthetic biological components and move towards more complex and therapy-oriented gene circuits. a comprehensive list of on-off switches, categorized into transcriptional, post-transcriptional, translational and post-translational, is presented in the first sections. subsequently, boolean logic gates, synthetic mammalian oscillators and toggle ... | 2015 | 25808341 |
| deciphering chicken gut microbial dynamics based on high-throughput 16s rrna metagenomics analyses. | chicken gut microbiota has paramount roles in host performance, health and immunity. understanding the topological difference in gut microbial community composition is crucial to provide knowledge on the functions of each members of microbiota to the physiological maintenance of the host. the gut microbiota profiling of the chicken was commonly performed previously using culture-dependent and early culture-independent methods which had limited coverage and accuracy. advances in technology based ... | 2015 | 25806087 |
| sublethal exposure to commercial formulations of the herbicides dicamba, 2,4-dichlorophenoxyacetic acid, and glyphosate cause changes in antibiotic susceptibility in escherichia coli and salmonella enterica serovar typhimurium. | biocides, such as herbicides, are routinely tested for toxicity but not for sublethal effects on microbes. many biocides are known to induce an adaptive multiple-antibiotic resistance phenotype. this can be due to either an increase in the expression of efflux pumps, a reduced synthesis of outer membrane porins, or both. exposures of escherichia coli and salmonella enterica serovar typhimurium to commercial formulations of three herbicides-dicamba (kamba), 2,4-dichlorophenoxyacetic acid (2,4-d), ... | 2015 | 25805724 |
| [frequency of antibodies to the recombinant protein p39 of c. jejuni in patients with gastrointestinal disorders and reactive arthritis in poland]. | campylobacterjejuni is has been found to be the leading cause of bacterial gastroenteritis worldwide. clinical manifestation on enterocolitis caused by c. jejuni are diarrhea, fever, abdominal pain and in some patients, fecal blood. after c. jejuni infection, squeals may occur such as reactive arthritis. the aim of the study was to investigate the frequency of antibodies to the recombinant protein p39 sticks c. jejuni in patients with gastrointestinal disorders and reactive arthritis in poland. | 2014 | 25804073 |
| prevention of biofilm formation and removal of existing biofilms by extracellular dnases of campylobacter jejuni. | the fastidious nature of the foodborne bacterial pathogen campylobacter jejuni contrasts with its ability to survive in the food chain. the formation of biofilms, or the integration into existing biofilms by c. jejuni, is thought to contribute to food chain survival. as extracellular dna (edna) has previously been proposed to play a role in c. jejuni biofilms, we have investigated the role of extracellular dnases (ednases) produced by c. jejuni in biofilm formation. a search of 2791 c. jejuni ge ... | 2015 | 25803828 |
| genomic, proteomic and morphological characterization of two novel broad host lytic bacteriophages φpd10.3 and φpd23.1 infecting pectinolytic pectobacterium spp. and dickeya spp. | pectinolytic pectobacterium spp. and dickeya spp. are necrotrophic bacterial pathogens of many important crops, including potato, worldwide. this study reports on the isolation and characterization of broad host lytic bacteriophages able to infect the dominant pectobacterium spp. and dickeya spp. affecting potato in europe viz. pectobacterium carotovorum subsp. carotovorum (pcc), p. wasabiae (pwa) and dickeya solani (dso) with the objective to assess their potential as biological disease control ... | 2015 | 25803051 |
| the investigation of correlation between iminoral concentration and neurotoxic levels after kidney transplantation. | neurotoxicity side effects related to cyclosporine kinetics could lead to dysfunction of kidney graft and patient outcome after transplantation. the aim of this study was evidence-based pharmacotherapy of kidney transplant recipients and to investigate neurotoxic levels of iminoral. | 2015 | 25802828 |
| traditional uses, phytochemistry, and pharmacology of olea europaea (olive). | aim of the review. to grasp the fragmented information available on the botany, traditional uses, phytochemistry, pharmacology, and toxicology of olea europaea to explore its therapeutic potential and future research opportunities. material and methods. all the available information on o. europaea was collected via electronic search (using pubmed, scirus, google scholar, and web of science) and a library search. results. ethnomedical uses of o. europaea are recorded throughout the world where it ... | 2015 | 25802541 |
| a prospective multi-center observational study of children hospitalized with diarrhea in ho chi minh city, vietnam. | we performed a prospective multicenter study to address the lack of data on the etiology, clinical and demographic features of hospitalized pediatric diarrhea in ho chi minh city (hcmc), vietnam. over 2,000 (1,419 symptomatic and 609 non-diarrheal control) children were enrolled in three hospitals over a 1-year period in 2009-2010. aiming to detect a panel of pathogens, we identified a known diarrheal pathogen in stool samples from 1,067/1,419 (75.2%) children with diarrhea and from 81/609 (13.3 ... | 2015 | 25802437 |
| helicobacter pylori flha binds the sensor kinase and flagellar gene regulatory protein flgs with high affinity. | flagellar biogenesis is a complex process that involves multiple checkpoints to coordinate transcription of flagellar genes with the assembly of the flagellum. in helicobacter pylori, transcription of the genes needed in the middle stage of flagellar biogenesis is governed by rpon and the two-component system consisting of the histidine kinase flgs and response regulator flgr. in response to an unknown signal, flgs autophosphorylates and transfers the phosphate to flgr, initiating transcription ... | 2015 | 25802298 |
| enteric bacterial pathogens in children with diarrhea in niger: diversity and antimicrobial resistance. | although rotavirus is the leading cause of severe diarrhea among children in sub-saharan africa, better knowledge of circulating enteric pathogenic bacteria and their antimicrobial resistance is crucial for prevention and treatment strategies. | 2015 | 25799400 |
| protection against multiple influenza a virus strains induced by candidate recombinant vaccine based on heterologous m2e peptides linked to flagellin. | matrix 2 protein ectodomain (m2e) is considered a promising candidate for a broadly protective influenza vaccine. m2e-based vaccines against human influenza a provide only partial protection against avian influenza viruses because of differences in the m2e sequences. in this work, we evaluated the possibility of obtaining equal protection and immune response by using recombinant protein on the basis of flagellin as a carrier of the m2e peptides of human and avian influenza a viruses. recombinant ... | 2015 | 25799221 |
| not seeing the forest for the trees: size of the minimum spanning trees (msts) forest and branch significance in mst-based phylogenetic analysis. | trees, including minimum spanning trees (msts), are commonly used in phylogenetic studies. but, for the research community, it may be unclear that the presented tree is just a hypothesis, chosen from among many possible alternatives. in this scenario, it is important to quantify our confidence in both the trees and the branches/edges included in such trees. in this paper, we address this problem for msts by introducing a new edge betweenness metric for undirected and weighted graphs. this spanni ... | 2015 | 25799056 |
| gene loss and lineage-specific restriction-modification systems associated with niche differentiation in the campylobacter jejuni sequence type 403 clonal complex. | campylobacter jejuni is a highly diverse species of bacteria commonly associated with infectious intestinal disease of humans and zoonotic carriage in poultry, cattle, pigs, and other animals. the species contains a large number of distinct clonal complexes that vary from host generalist lineages commonly found in poultry, livestock, and human disease cases to host-adapted specialized lineages primarily associated with livestock or poultry. here, we present novel data on the st403 clonal complex ... | 2015 | 25795671 |
| a review approaches to identify enteric bacterial pathogens. | diarrhea is a common disease across the world. according to who, every year about two billion cases of diarrhea are reported in the world. it occurs mainly in the tropical regions and is a main cause of morbidity and mortality, particularly in young children and adults. | 2014 | 25793091 |
| a review approaches to identify enteric bacterial pathogens. | diarrhea is a common disease across the world. according to who, every year about two billion cases of diarrhea are reported in the world. it occurs mainly in the tropical regions and is a main cause of morbidity and mortality, particularly in young children and adults. | 2014 | 25793091 |
| mycoplasma pneumoniae infection with neurologic complications. | extrapulmonary complications of mycoplasma pneumoniae (m. pneumoniae) infection include encephalitis, optic neuritis, acute psychosis, stroke, cranial nerve palsies, aseptic meningitis and also it may be implicated in immune mediated neurological diseases such as acute demyelinating encephalomyelitis, guillain-barre syndrome and transverse myelitis. | 2014 | 25793076 |
| the bacterial communities associated with fecal types and body weight of rex rabbits. | rex rabbit is an important small herbivore for fur and meat production. however, little is known about the gut microbiota in rex rabbit, especially regarding their relationship with different fecal types and growth of the hosts. we characterized the microbiota of both hard and soft feces from rex rabbits with high and low body weight by using the illumina miseq platform targeting the v4 region of the 16s rdna. high weight rex rabbits possess distinctive microbiota in hard feces, but not in soft ... | 2015 | 25791609 |
| effect of exposure to stress conditions on propidium monoazide (pma)-qpcr based campylobacter enumeration in broiler carcass rinses. | campylobacter quantification by qpcr is unable to distinguish viable vs. dead cells in contrast to the culture-based iso 10272-2 reference method. propidium monoazide (pma) has been used to overcome this disadvantage. a campylobacter pma-qpcr enumeration method was evaluated for its consistency and compared to the culture-based enumeration for both artificially and natural contaminated broiler carcass rinses. the pma effect was further evaluated on stressed cells. five conditions, commonly encou ... | 2015 | 25791007 |
| milk proteins, peptides, and oligosaccharides: effects against the 21st century disorders. | milk is the most complete food for mammals, as it supplies all the energy and nutrients needed for the proper growth and development of the neonate. milk is a source of many bioactive components, which not only help meeting the nutritional requirements of the consumers, but also play a relevant role in preventing various disorders. milk-derived proteins and peptides have the potential to act as coadjuvants in conventional therapies, addressing cardiovascular diseases, metabolic disorders, intest ... | 2015 | 25789308 |
| refinement of whole-genome multilocus sequence typing analysis by addressing gene paralogy. | we developed a user-friendly program, genome profiler (gep), to refine whole-genome multilocus sequence typing analysis by addressing gene paralogy with conserved gene neighborhoods. in comparison to similar programs, gep produced overall the best results in terms of accuracy and is thus a useful alternative to resolve relationships of bacterial isolates. | 2015 | 25788543 |
| the challenge of efflux-mediated antibiotic resistance in gram-negative bacteria. | the global emergence of multidrug-resistant gram-negative bacteria is a growing threat to antibiotic therapy. the chromosomally encoded drug efflux mechanisms that are ubiquitous in these bacteria greatly contribute to antibiotic resistance and present a major challenge for antibiotic development. multidrug pumps, particularly those represented by the clinically relevant acrab-tolc and mex pumps of the resistance-nodulation-division (rnd) superfamily, not only mediate intrinsic and acquired mult ... | 2015 | 25788514 |
| noroviruses as a cause of diarrhea in immunocompromised pediatric hematopoietic stem cell and solid organ transplant recipients. | case reports describe significant norovirus gastroenteritis morbidity in immunocompromised patients. we evaluated norovirus pathogenesis in prospectively enrolled solid organ (sot) and hematopoietic stem cell transplant (hsct) patients with diarrhea who presented to texas children's hospital and submitted stool for enteric testing. noroviruses were detected by real-time reverse transcription polymerase chain reaction. clinical outcomes of norovirus diarrhea and non-norovirus diarrhea patients, m ... | 2015 | 25788003 |
| citrus bergamia essential oil: from basic research to clinical application. | citrus bergamia risso et poiteau, also known as "bergamot," is a plant belonging to the rutaceae family, defined as a hybrid of bitter orange and lemon. it is an endemic plant of the calabria region (italy). bergamot fruit is primarily used for the extraction of its essential oil (bergamot essential oil: beo), employed in perfume, cosmetics, food, and confections. the aim of this review was to collect recent data from the literature on c. bergamia essential oil and, through a critical analysis, ... | 2015 | 25784877 |
| the anabaena sp. pcc 7120 exoproteome: taking a peek outside the box. | the interest in examining the subset of proteins present in the extracellular milieu, the exoproteome, has been growing due to novel insights highlighting their role on extracellular matrix organization and biofilm formation, but also on homeostasis and development. the cyanobacterial exoproteome is poorly studied, and the role of cyanobacterial exoproteins on cell wall biogenesis, morphology and even physiology is largely unknown. here, we present a comprehensive examination of the anabaena sp. ... | 2015 | 25782455 |
| crystal structure of helicobacter pylori pseudaminic acid biosynthesis n-acetyltransferase pseh: implications for substrate specificity and catalysis. | helicobacter pylori infection is the common cause of gastroduodenal diseases linked to a higher risk of the development of gastric cancer. persistent infection requires functional flagella that are heavily glycosylated with 5,7-diacetamido-3,5,7,9-tetradeoxy-l-glycero-l-manno-nonulosonic acid (pseudaminic acid). pseudaminic acid biosynthesis protein h (pseh) catalyzes the third step in its biosynthetic pathway, producing udp-2,4-diacetamido-2,4,6-trideoxy-β-l-altropyranose. it belongs to the gcn ... | 2015 | 25781966 |
| analysis of resistance to antimicrobials and presence of virulence/stress response genes in campylobacter isolates from patients with severe diarrhoea. | campylobacter infections are a major cause of diarrhoea world-wide and two of the antimicrobials used for their control (erythromycin and ciprofloxacin) have been losing efficacy in recent years. in a sample of 174 genotyped isolates from the stools of patients with severe diarrhoea in qatar, collected between 2005 and 2012, 63.2% showed resistance to ciprofloxacin, 8.6% to erythromycin, 0.57% to chloramphenicol and all were sensitive to gentamycin. while 33.9% of isolates were sensitive to all ... | 2015 | 25781009 |
| selected enteropathogens and clinical course in children hospitalized with severe acute gastroenteritis in barbados. | the primary aim of this study was to determine the prevalence of selected bacterial and viral enteropathogens in children hospitalized with acute gastroenteritis and the secondary aim was to characterize the clinical course and the outcome. | 2014 | 25780359 |
| optimal cloning of pcr fragments by homologous recombination in escherichia coli. | pcr fragments and linear vectors containing overlapping ends are easily assembled into a propagative plasmid by homologous recombination in escherichia coli. although this gap-repair cloning approach is straightforward, its existence is virtually unknown to most molecular biologists. to popularize this method, we tested critical parameters influencing the efficiency of pcr fragments cloning into pcr-amplified vectors by homologous recombination in the widely used e. coli strain dh5α. we found th ... | 2015 | 25774528 |
| higher resistance of campylobacter coli compared to campylobacter jejuni at chicken slaughterhouse. | in order to compare the prevalence of campylobacter coli and campylobacter jejuni during the processing of broilers at slaughterhouse a total of 848 samples were analyzed during 2012 in southern spain. four hundred and seventy six samples were collected from cloaca, carcass surfaces and quartered carcasses. moreover, 372 environmental swabs from equipment and scalding water were collected. minimum inhibitory concentration (mic) to ciprofloxacin, erythromycin, streptomycin, tetracycline and genta ... | 2015 | 25770597 |
| prevalence and characterization of campylobacter jejuni from chicken meat sold in french retail outlets. | campylobacter was detected in 76% of broiler meat products collected in retail outlets during a monitoring plan carried out in france throughout 2009. campylobacter jejuni was the most prevalent species (64.7% of products being contaminated). the 175 c. jejuni isolates collected were characterized. mlst typing results confirmed substantial genetic diversity as the 175 c. jejuni isolates generated 76 sequence types (sts). the st-21, st-45 and st-464 complexes predominated accounting for 43% of al ... | 2015 | 25770428 |
| genes indicative of zoonotic and swine pathogens are persistent in stream water and sediment following a swine manure spill. | manure spills into streams are relatively frequent, but no studies have characterized stream contamination with zoonotic and veterinary pathogens, or fecal chemicals, following a spill. we tested stream water and sediment over 25 days and downstream for 7.6 km for the following: fecal indicator bacteria (fib), the fecal indicator chemicals cholesterol and coprostanol, 20 genes for zoonotic and swine-specific bacterial pathogens by presence/absence pcr for viable cells, one swine-specific escheri ... | 2015 | 25769829 |
| taxonomic identification of ruminal epithelial bacterial diversity during rumen development in goats. | understanding of the colonization process of epithelial bacteria attached to the rumen tissue during rumen development is very limited. ruminal epithelial bacterial colonization is of great significance for the relationship between the microbiota and the host and can influence the early development and health of the host. miseq sequencing of 16s rrna genes and quantitative real-time pcr (qpcr) were applied to characterize ruminal epithelial bacterial diversity during rumen development in this st ... | 2015 | 25769827 |
| role of capsular modified heptose in the virulence of campylobacter jejuni. | the campylobacter jejuni capsular polysaccharide is important for virulence and often contains a modified heptose. in strain atcc 700819 (a.k.a. nctc 11168), the modified heptose branches off from the capsular backbone and is directly exposed to the environment. we reported previously that the enzymes encoded by wcag, mlghb and mlghc are involved in heptose modification. here, we show that inactivation of any of these genes leads to production of capsule lacking modified heptose and alters the t ... | 2015 | 25766665 |
| identification of campylobacter jejuni and determination of point mutations associated with macrolide resistance using a multiplex taqman mgb real-time pcr. | the aim of the study was to develop a multiplex real-time pcr method to identify campylobacter jejuni containing mutations commonly associated with macrolide resistance. | 2015 | 25766481 |
| detection of thermophilic campylobacter sp. in raw chicken sausages by methods iso 10272: 2006 in curitiba - parana state - brazil. | the aim of this study was the detection of campylobacter sp. in raw chicken sausages using the methods iso 10272-1 and iso 10272-2. the overall prevalence of campylobacter sp. in the samples tested was 16.67%, representing a serious risk to the health of consumers, particularly if measures guaranteeing proper cooking of foods and prevention of cross-contamination are not adopted. furthermore, the majority of campylobacteriosis cases in humans are caused by consumption or improper handling of con ... | 2015 | 25763066 |
| detection of thermophilic campylobacter sp. in raw chicken sausages by methods iso 10272: 2006 in curitiba - parana state - brazil. | the aim of this study was the detection of campylobacter sp. in raw chicken sausages using the methods iso 10272-1 and iso 10272-2. the overall prevalence of campylobacter sp. in the samples tested was 16.67%, representing a serious risk to the health of consumers, particularly if measures guaranteeing proper cooking of foods and prevention of cross-contamination are not adopted. furthermore, the majority of campylobacteriosis cases in humans are caused by consumption or improper handling of con ... | 2015 | 25763066 |
| pcr for enteric pathogens in high-prevalence settings. what does a positive signal tell us? | molecular methods, in particular pcr, are increasingly used for the diagnosis of enteric pathogens in stool samples. in high-endemicity settings, however, asymptomatic carriage or residual dna from previous infections will hamper the interpretation of positive test results. we assessed the quantitative dimension of this problem in schoolchildren in the rural highlands of madagascar. | 2015 | 25761823 |
| selective biochemical labeling of campylobacter jejuni cell-surface glycoconjugates. | the display of cell-surface glycolipids and glycoproteins is essential for the motility, adhesion and colonization of pathogenic bacteria such as campylobacter jejuni. recently, the cell-surface display of c. jejuni glycoconjugates has been the focus of considerable attention; however, our understanding of the roles that glycosylation plays in bacteria still pales in comparison with our understanding of mammalian glycosylation. one of the reasons for this is that carbohydrate metabolic labeling, ... | 2015 | 25761366 |
| [infection due to mycobacterium bovis in common variable immunodeficiency]. | common variable immunodeficiency (cvid) is an heterogeneous group of disorders characterized by impaired antibody production. it shows a wide spectrum of manifestations including severe and recurrent respiratory infections (streptococcus pneumoniae, haemophilus) and gastrointestinal (campylobacter jejuni, rotavirus and giardia lamblia). viral infections caused by herpes zoster, cytomegalovirus (cmv) and hepatitis c are rare. the opportunistic agents such as cmv, pneumocystis jirovecii, cryptococ ... | 2017 | 25758115 |
| next generation sequencing analysis reveals that the ribonucleases rnase ii, rnase r and pnpase affect bacterial motility and biofilm formation in e. coli. | the rna steady-state levels in the cell are a balance between synthesis and degradation rates. although transcription is important, rna processing and turnover are also key factors in the regulation of gene expression. in escherichia coli there are three main exoribonucleases (rnase ii, rnase r and pnpase) involved in rna degradation. although there are many studies about these exoribonucleases not much is known about their global effect in the transcriptome. | 2015 | 25757888 |
| contribution of surface polysaccharides to the resistance of campylobacter jejuni to antimicrobial phenolic compounds. | 2015 | 25757605 | |
| campylobacter-acanthamoeba interactions. | campylobacter jejuni is a foodborne pathogen recognized as the major cause of human bacterial enteritis. undercooked poultry products and contaminated water are considered as the most important sources of infection. some studies suggest transmission and survival of this bacterial pathogen may be assisted by the free-living protozoa acanthamoeba. the latter is known to play the role of a host for various pathogenic bacteria, protecting them from harsh environmental conditions. importantly, there ... | 2015 | 25757600 |
| role of pd-1 co-inhibitory pathway in hiv infection and potential therapeutic options. | virus-specific cd8+ t cells play an important role in controlling viral infections including human immunodeficiency virus (hiv) infection. however, during chronic hiv infection, virus-specific cd8+ t cells undergo functional exhaustion, lose effector functions and fail to control viral infection. hiv-specific cd8 t cells expressing high levels of co-inhibitory molecule programmed death-1 (pd-1) during the chronic infection and are characterized by lower proliferation, cytokine production, and cy ... | 2015 | 25756928 |
| molecular structure of an n-formyltransferase from providencia alcalifaciens o30. | the existence of n-formylated sugars in the o-antigens of gram-negative bacteria has been known since the middle 1980s, but only recently have the biosynthetic pathways for their production been reported. in these pathways, glucose-1-phosphate is first activated by attachment to a dtmp moiety. this step is followed by a dehydration reaction and an amination. the last step in these pathways is catalyzed by n-formyltransferases that utilize n(10) -formyltetrahydrofolate as the carbon source. here ... | 2015 | 25752909 |
| co-infection of the siberian hamster (phodopus sungorus) with a novel helicobacter sp. and campylobacter sp. | we report the isolation of a novel helicobacter isolated from the caecum of the siberian hamster (phodopus sungorus). sequence analysis showed 97% sequence similarity to helicobacter ganmani. in addition, we report the co-infection of these siberian hamsters with a campylobacter sp. and a second helicobacter sp. with 99% sequence similarity to helicobacter sp. flexispira taxon 8 (helicobacter bilis), a species isolated previously from patients with bacteraemia. gross necropsy and histopathology ... | 2015 | 25752854 |
| the capability of pseudomonas aeruginosa to recruit zinc under conditions of limited metal availability is affected by inactivation of the znuabc transporter. | the ability of a large number of bacterial pathogens to multiply in the infected host and cause disease is dependent on their ability to express high affinity zinc importers. in many bacteria, znuabc, a transporter of the abc family, plays a central role in the process of zinc uptake in zinc poor environments, including the tissues of the infected host. to initiate an investigation into the relevance of the zinc uptake apparatus for pseudomonas aeruginosa pathogenicity, we have generated a znua ... | 2015 | 25751674 |
| modulation of bacterial multidrug resistance efflux pumps of the major facilitator superfamily. | bacterial infections pose a serious public health concern, especially when an infectious disease has a multidrug resistant causative agent. such multidrug resistant bacteria can compromise the clinical utility of major chemotherapeutic antimicrobial agents. drug and multidrug resistant bacteria harbor several distinct molecular mechanisms for resistance. bacterial antimicrobial agent efflux pumps represent a major mechanism of clinical resistance. the major facilitator superfamily (mfs) is one o ... | 2013 | 25750934 |
| life history correlates of fecal bacterial species richness in a wild population of the blue tit cyanistes caeruleus. | very little is known about the normal gastrointestinal flora of wild birds, or how it might affect or reflect the host's life-history traits. the aim of this study was to survey the species richness of bacteria in the feces of a wild population of blue tits cyanistes caeruleus and to explore the relationships between bacterial species richness and various life-history traits, such as age, sex, and reproductive success. using pcr-tgge, 55 operational taxonomic units (otus) were identified in blue ... | 2015 | 25750710 |
| lactic acid bacteria--20 years exploring their potential as live vectors for mucosal vaccination. | lactic acid bacteria (lab) are a diverse group of gram-positive, nonsporulating, low g + c content bacteria. many of them have been given generally regarded as safe status. over the past two decades, intensive genetic and molecular research carried out on lab, mainly lactococcus lactis and some species of the lactobacillus genus, has revealed new, potential biomedical lab applications, including the use of lab as adjuvants, immunostimulators, or therapeutic drug delivery systems, or as factories ... | 2015 | 25750046 |
| recombinant escherichia coli strains with inducible campylobacter jejuni single domain hemoglobin chb expression exhibited improved cell growth in bioreactor culture. | maintaining an appropriate concentration of dissolved oxygen in aqueous solution is critical for efficient operation of a bioreactor, requiring sophisticated engineering design and a system of regulation to maximize oxygen transfer from the injected air bubbles to the cells. bacterial hemoglobins are oxygen-binding proteins that transfer oxygen from the environment to metabolic processes and allow bacteria to grow even under microaerophilic conditions. to improve the oxygen utilization efficienc ... | 2015 | 25748170 |
| a highly sensitive elisa and immunochromatographic strip for the detection of salmonella typhimurium in milk samples. | murine monoclonal antibodies to target salmonella typhimurium flagellin and lipopolysaccharide (lps) were prepared and characterized. for the immunological detection of s. typhimurium, different pairs of monoclonal antibodies (mabs) were tested in a sandwich enzyme linked immunosorbent assay (elisa) format. after comparison, a sandwich elisa and immunochromatographic strip based on lps mabs was established to detect s. typhimurium. the determination limits of the immunochromatographic strip in p ... | 2015 | 25746094 |
| prevalence of enteric pathogen-associated community gastroenteritis among kindergarten children in gaza. | gastroenteritis is considered as one of the leading causes of illness and death in children under 5 years age, especially in developing countries. it is one of the major public health problems among childhood in gaza strip, palestine. this study was conducted to determine the prevalence of enteric pathogen-associated community gastroenteritis among kindergarten children in gaza. a total of 150 stool samples were collected and investigated for parasitic, viral and bacterial pathogens at al azhar ... | 2014 | 25745477 |
| prevalence of enteric pathogen-associated community gastroenteritis among kindergarten children in gaza. | gastroenteritis is considered as one of the leading causes of illness and death in children under 5 years age, especially in developing countries. it is one of the major public health problems among childhood in gaza strip, palestine. this study was conducted to determine the prevalence of enteric pathogen-associated community gastroenteritis among kindergarten children in gaza. a total of 150 stool samples were collected and investigated for parasitic, viral and bacterial pathogens at al azhar ... | 2014 | 25745477 |
| pediatric guillain-barré syndrome: indicators for a severe course. | this study aims to retrospectively evaluate pediatric guillain-barré syndrome cases in a tertiary center in istanbul, turkey. | 2015 | 25745306 |