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chlamydia trachomatis infection in women: a case for more action? 19862871453
medical education in east london. 20102871369
quantitative studies of n-methyl-d-aspartate, 2-amino-5-phosphonovalerate and cis-2,3-piperidine dicarboxylate interactions on the neonatal rat spinal cord in vitro.the interactions between n-methyl-d-aspartate (nmda), (+/-)2-amino-5-phosphonovalerate (2ap5) and (+/-)cis-2.3-piperidine dicarboxylate (cis-pda) were examined quantitatively in the neonatal rat spinal cord in vitro. nmda and cis-pda evoked concentration-dependent motoneuronal depolarizations. the maximal cis-pda-evoked response was approximately 60% of that evoked by nmda. when applied in combination with fixed concentrations of cis-pda, nmda evoked concentration-dependent depolarizations super ...19862870929
quantitative studies of n-methyl-d-aspartate, 2-amino-5-phosphonovalerate and cis-2,3-piperidine dicarboxylate interactions on the neonatal rat spinal cord in vitro.the interactions between n-methyl-d-aspartate (nmda), (+/-)2-amino-5-phosphonovalerate (2ap5) and (+/-)cis-2.3-piperidine dicarboxylate (cis-pda) were examined quantitatively in the neonatal rat spinal cord in vitro. nmda and cis-pda evoked concentration-dependent motoneuronal depolarizations. the maximal cis-pda-evoked response was approximately 60% of that evoked by nmda. when applied in combination with fixed concentrations of cis-pda, nmda evoked concentration-dependent depolarizations super ...19862870929
skin lysyl oxidase activity is not rate limiting for collagen crosslinking in the glucocorticoid-treated rat.lysyl oxidase activity in the skin of rats receiving triamcinolone diacetate (12 mg/kg) for three consecutive days was decreased by sixty-four percent as compared to control values. a decrease of lysyl oxidase activity was observed twelve hours after the initial glucocorticoid injection. the decreased lysyl oxidase activity was accompanied by a forty-nine percent decrease of acetic acid extractable collagen. there was also a forty-two percent decrease in the alpha/beta ratio of the acetic acid s ...19862870873
skin lysyl oxidase activity is not rate limiting for collagen crosslinking in the glucocorticoid-treated rat.lysyl oxidase activity in the skin of rats receiving triamcinolone diacetate (12 mg/kg) for three consecutive days was decreased by sixty-four percent as compared to control values. a decrease of lysyl oxidase activity was observed twelve hours after the initial glucocorticoid injection. the decreased lysyl oxidase activity was accompanied by a forty-nine percent decrease of acetic acid extractable collagen. there was also a forty-two percent decrease in the alpha/beta ratio of the acetic acid s ...19862870873
blood-finding strategy of a capillary-feeding sandfly, lutzomyia longipalpis.salivary gland homogenates of adult female lutzomyia longipalpis inhibited platelet aggregation induced by adp and collagen. apyrase (atp diphosphohydrolase) activity was prominent, requiring ca2+ but not mg2+ and a ph optimum of 8.0. human as well as rabbit hosts developed a well delimited erythema, evident 2-3 min after initial probing and lasting for as long as 2 days. erythema, not accompanied by itching or swelling, developed in previously exposed hosts as well as in those not previously ex ...19862870860
blood-finding strategy of a capillary-feeding sandfly, lutzomyia longipalpis.salivary gland homogenates of adult female lutzomyia longipalpis inhibited platelet aggregation induced by adp and collagen. apyrase (atp diphosphohydrolase) activity was prominent, requiring ca2+ but not mg2+ and a ph optimum of 8.0. human as well as rabbit hosts developed a well delimited erythema, evident 2-3 min after initial probing and lasting for as long as 2 days. erythema, not accompanied by itching or swelling, developed in previously exposed hosts as well as in those not previously ex ...19862870860
the energetic cost of various behaviors in the laboratory mouse.the continuous 12-hr observation of a mouse placed in a respiratory chamber has made it possible to record the succession of behaviors of the animal, as well as the associated variations of co2 concentrations in the chamber. ten behaviors have been considered; these included rest, locomotion, sniffing, feeding, drinking, nest building and various types of grooming. these data have been used for the estimation, by means of kalman filtering, of the energetic cost of each behavior. thus, at 20 degr ...19862870847
the energetic cost of various behaviors in the laboratory mouse.the continuous 12-hr observation of a mouse placed in a respiratory chamber has made it possible to record the succession of behaviors of the animal, as well as the associated variations of co2 concentrations in the chamber. ten behaviors have been considered; these included rest, locomotion, sniffing, feeding, drinking, nest building and various types of grooming. these data have been used for the estimation, by means of kalman filtering, of the energetic cost of each behavior. thus, at 20 degr ...19862870847
effects of growth hormone on glucose and acetate metabolism in sheep.the effect of intravenous infusion of growth hormone (gh) on glucose metabolism in sheep was determined. to maintain low levels of insulin somatostatin was infused with and without gh. the infusion of gh for 6 hr was without effect on glucose metabolism.19862870845
[efficacy and tolerance to mebhydroline in comparison with dimetindene maleate]. 20072870838
[efficacy and tolerance to mebhydroline in comparison with dimetindene maleate]. 20072870838
an in vivo voltammetric comparison of the effects of three psychomotor stimulants on electrically evoked neostriatal dopamine release.the effects of three psychomotor stimulants (mazindol, beta-phenylethylamine and d-phenmetrazine) on electrically evoked neostriatal dopamine release were studied by in vivo voltammetry. mazindol (10 mg/kg) enhanced release and this effect persisted after dopamine synthesis inhibition by alpha-methyl-p-tyrosine. beta-phenylethylamine (100 mg/kg) caused a large decrease in stimulated dopamine release and exerted no effect after dopamine synthesis inhibition. d-phenmetrazine (45 mg/kg) enhanced do ...19862870765
an in vivo voltammetric comparison of the effects of three psychomotor stimulants on electrically evoked neostriatal dopamine release.the effects of three psychomotor stimulants (mazindol, beta-phenylethylamine and d-phenmetrazine) on electrically evoked neostriatal dopamine release were studied by in vivo voltammetry. mazindol (10 mg/kg) enhanced release and this effect persisted after dopamine synthesis inhibition by alpha-methyl-p-tyrosine. beta-phenylethylamine (100 mg/kg) caused a large decrease in stimulated dopamine release and exerted no effect after dopamine synthesis inhibition. d-phenmetrazine (45 mg/kg) enhanced do ...19862870765
bronchodilator effects of terbutaline and theophylline alone and in combination in patients with chronic obstructive lung disease.thirteen patients with severe partially reversible chronic obstructive lung disease received long-term treatment with a sustained-release preparation of theophylline and a beta 2-agonist (terbutaline) alone and in combination. combination therapy induced significantly greater bronchodilation than treatment with terbutaline alone in the recommended dose. in 9 out of 13 patients the peak flows were higher during combination therapy than during theophylline treatment alone, but this did not reach s ...20062870630
bronchodilator effects of terbutaline and theophylline alone and in combination in patients with chronic obstructive lung disease.thirteen patients with severe partially reversible chronic obstructive lung disease received long-term treatment with a sustained-release preparation of theophylline and a beta 2-agonist (terbutaline) alone and in combination. combination therapy induced significantly greater bronchodilation than treatment with terbutaline alone in the recommended dose. in 9 out of 13 patients the peak flows were higher during combination therapy than during theophylline treatment alone, but this did not reach s ...20062870630
[nailbed transplantation, a possibility for reconstruction].to satisfy the demands of tactile gnosis, it is necessary to have intact fingertips. for this purpose, the fingernail has an important function. with the help of an example of a nailbed transplantation after a complete amputation of a finger end, a possibility of reconstruction of injured fingertips, especially of the nailbed, is shown. attention is called to the importance of an exact primary treatment of injured nailbeds.20062870619
[nailbed transplantation, a possibility for reconstruction].to satisfy the demands of tactile gnosis, it is necessary to have intact fingertips. for this purpose, the fingernail has an important function. with the help of an example of a nailbed transplantation after a complete amputation of a finger end, a possibility of reconstruction of injured fingertips, especially of the nailbed, is shown. attention is called to the importance of an exact primary treatment of injured nailbeds.20062870619
prescription and misuse of benzodiazepines in the federal republic of germany.reliable benzodiazepine prescription data are now available for the federal republic of germany by the establishment of gkv-index. in 1981, 4 benzodiazepines were among the 25 highest ranking drugs in the frg according to total number of prescriptions. a decline of benzodiazepine prescriptions was observed in 1983 and 1984; two short-acting compounds achieved a higher ranking position. benzodiazepines make up to about two thirds of all psychotropic drugs prescribed. these data are compared to so ...20062870514
platelet aggregation caused by carybdea rastonii toxins (crtx-i, ii and iii) obtained from a jellyfish, carybdea rastonii.the pharmacological mechanisms of platelet aggregation induced by highly toxic proteins (crtx-i, crtx-ii, and crtx-iii) obtained from tentacles of a jellyfish, carybdea rastonii, were investigated. when the partially purified toxin (pcrtx) and crtxs were added to the citrated platelet-rich plasma (prp), aggregation was produced in a concentration-dependent manner. the activity of crtxs was approximately 100 times more potent than pcrtx. the crtxs-induced aggregation was little affected by indome ...19862870502
antigenic variation of gonococcal pilus involves assembly of separated silent gene segments.the pilus is a major outer-membrane protein of neisseria gonorrhoeae that undergoes phase and antigenic variation. in strain ms11 pilus expression is regulated at two expression loci on the chromosome, pile1 and pile2, although many other regions contain silent pilin information. a comparison of variant pilin sequences has revealed that the gene can be divided into a constant, a semivariable, and a hypervariable region. we report here that complete pilin genes are found only at the expression lo ...19862870495
integrating treatments in schizophrenia.schizophrenia is a common and severe illness found throughout the world. onset is usually in adolescence and young adulthood, and many individuals have illness-related impairments for life. schizophrenia assaults the very essence of what is distinctly human. the personality is devastated, subjective experience and thought distorted, and the psychological building blocks of everyday life torn asunder. this article discusses diagnostic and conceptual considerations, pharmacotherapy, and interperso ...19862870478
accessory adrenal: an incidental finding during orchiopexy. 20062870456
accessory adrenal: an incidental finding during orchiopexy. 20062870456
transglutaminase and neuronal differentiation.during mouse brain maturation cellular transglutaminase specific activity increases 2.5 fold from day 3 to adulthood. a more pronounced increase is seen during morphological differentiation of mouse neuroblastoma cells, where serum withdrawal induces neurite outgrowth concomitant with a 10 fold increase in transglutaminase specific activity. in contrast, non-dividing neuroblastoma cells lacking neurites show only a 1.5 fold increase in enzyme specific activity. transglutaminase activity does not ...19862870428
transglutaminase and neuronal differentiation.during mouse brain maturation cellular transglutaminase specific activity increases 2.5 fold from day 3 to adulthood. a more pronounced increase is seen during morphological differentiation of mouse neuroblastoma cells, where serum withdrawal induces neurite outgrowth concomitant with a 10 fold increase in transglutaminase specific activity. in contrast, non-dividing neuroblastoma cells lacking neurites show only a 1.5 fold increase in enzyme specific activity. transglutaminase activity does not ...19862870428
[nature of the larval feeding of blood-sucking mosquitoes (diptera, culicidae) in the bodies of water upstream of the kakhovka reservoir]. 20052870419
[nature of the larval feeding of blood-sucking mosquitoes (diptera, culicidae) in the bodies of water upstream of the kakhovka reservoir]. 20052870419
occult-blood screening. 20062870371
conformationally defined adrenergic agents. 2. catechol imidazoline derivatives: biological effects at alpha 1 and alpha 2 adrenergic receptors.the synthesis and pharmacology of 2-(5,6-dihydroxy-1,2,3,4-tetrahydro-1-naphthyl)imidazoline (a-54741, 4), a very potent alpha-adrenergic agonist, are described. the change in biological activity resulting from variation of the carbocyclic ring size of 4 from four through seven members (2-5) is presented, as well as an explanation that accounts for this change in activity by considering the "exactness of fit" of these compounds to both the alpha 1- and alpha 2-adrenergic receptors. compound 4 wa ...19862870187
dynorphin- and enkephalin-like immunoreactivity is altered in limbic-basal ganglia regions of rat brain after repeated electroconvulsive shock.in an attempt to determine whether the opioid peptides derived from prodynorphin participate in the effects of electroconvulsive shock (ecs), we used radioimmunoassay and immunocytochemistry to measure dynorphin-like immunoreactivity (dn-li) in various rat brain regions after repeated ecs treatments. ten daily ecss caused a significant increase in dynorphin a (1-8)-li in most limbic-basal ganglia structures, including hypothalamus (50%), striatum (30%), and septum (30%). no significant change wa ...19862870139
[consequences of antral and duodenal acidification on acid secretion, gastrin response and gastric emptying in duodenal ulcer patients and normal subjects].the present study intended to investigate the effect of antroduodenal acidification on gastric acid secretion and emptying, gastrin and somatostatin release in response to food in healthy subjects as well as in duodenal ulcer patients. ten duodenal ulcer patients and 9 normal controls were studied twice: the same 400 ml liquid protein meal (proteins: 10 g) was introduced into the stomach; then intragastric ph was either maintained at ph 4.5 or allowed to decrease in response to the meal. acid se ...20032870001
[viral replication and hepatic manifestations in 7 cases of periarteritis nodosa associated with hepatitis b virus].viral replication was studied in 7 cases of pan associated with hepatitis b virus (hbv). serum and liver were strongly positive for markers reflecting hbv replication (constant high levels of hbe ag, numerous hepatocytes nuclei reactive for hbc ag, high dna-polymerase activity). no cases were found to be positive for delta antigen or antibody. mild biological and histological signs of liver damage were present in all patients but one. in pan, high replication might lead to continuous stimulation ...19862870000
influence of thyroidectomy on brain catecholamines during the postnatal period.the influence of early thyroidectomy (tx) on changes in dopamine (da) and noradrenaline (na) during the postnatal period (30, 45 and 60 days old) was studied in the diencephalon and the rest of the brain of male and female rats. thyroidectomy interfered with the normal growth of the animals, decreased brain weight and markedly influenced the developmental pattern of both da and na in the diencephalon. when compared with control values, the da concentration, in 45- and 60-day-old tx male rats, wa ...19862869883
effect of activated lymphocytes on the regulation of hematopoiesis: enhancement and suppression of in vitro bfu-e growth by t cells stimulated by autologous non-t cells.autologous mixed lymphocyte culture (amlr) is an immunologic response with memory and specificity and plays a role in immune regulation. effects of t cells activated by amlr were studied in the regulation of in vitro erythropoiesis. amlr-activated t cells were cocultured with autologous non-t, nonphagocytic peripheral blood mononuclear cells for assaying erythroid progenitor cells (bfu-e). t cells activated for 3 days in amlr showed significant enhancement of in vitro colony growth by bfu-e. in ...20022869804
bone marrow structure and its possible significance for hematopoietic cell renewal.the authors review the progress made during the last quarter of a century in the fields of hematopoietic cellular proliferation and differentiation in relation to the bone marrow structure and the microenvironment provided by the marrow stroma in which unlimited self-renewal occurs. the marrow is conceived of as an organ in which the stroma originates from local mesenchymal elements which form a vascularized and innervated matrix, seeded later by blood-borne stem cells. transplantation studies u ...19852869731
alfentanil's analgesic, respiratory, and cardiovascular actions in relation to dose and plasma concentration in unanesthetized dogs.relationships between plasma concentrations of alfentanil and its analgesic, respiratory, and cardiovascular effects were determined in dogs. to avoid drug interaction, trained, unanesthetized, spontaneously breathing dogs were used. after a control period in the awake state, alfentanil was injected in increasing amounts (10, 20, 80, 160, and 320 micrograms/kg) at 5-min intervals to a total dose of 590 micrograms/kg administered over 20 min. the effects were observed on pain responses (heart rat ...19862869724
[beta-mimetics and tachyphylaxis].this study covers current knowledge concerning the risks of tachyphylaxis induced by prolonged use of beta-mimetics in the asthmatic. the organization of the adrenergic membrane system is reviewed, as well as the various mechanisms which may lead to desensitization. experimental evidence of the latter is described. the most extensive studies have involved circulating cells and, more precisely, lymphocytes and polynuclear neutrophils. clinical trials are then dealt with. studies concerned with br ...20002869566
[comparisons of vasoconstrictions induced by alpha agonists either in the luminal perfusate or in the adventitial superfusate]. 19852869558
severe cutaneous adverse reactions to sulfadoxine-pyrimethamine in switzerland. 20102869315
vasovagal syncope? 20102869309
alpha-tocopherol as agonist in hypoxia.in hypoxia, but not normoxia, alpha-tocopherol (vitamin e) acts as an agonist in guinea-pig isolated colon, producing dose-dependent increases in contractile activity. this effect is mimicked by agents, vitamin k1 and phytol, which contain a structural similarity to the phytol side chain of alpha-tocopherol, but is antagonized by vitamin k3 which has a structure similar to the chromane ring of vitamin e. all of the agonist responses were blocked by atropine and potentiated by physostigmine but w ...19862869132
induction of procollagen processing in fibroblast cultures by neutral polymers.in cultures of dermal fibroblasts, procollagen and the intermediates pc- and pn-collagen accumulated in the culture medium with little further processing to collagen. when polyethylene glycol (peg) or other neutral polymers were added to fibroblast culture medium, no collagen or procollagen was found in the medium, but all the collagen was associated with the cell layer. the type i procollagen was fully processed to collagen with an initial transient accumulation of pn-collagen, and the processe ...19862869039
delayed flare-up reactions caused by jellyfish.four patients had a recurrence of cutaneous lesions 1 week after being stung by jellyfish. three patients had flare-up lesions after only one exposure to jellyfish. all of the recurring lesions were vesicular erythema, and the histological findings of case 3 corresponded to that of allergic contact dermatitis.20092868932
delayed flare-up reactions caused by jellyfish.four patients had a recurrence of cutaneous lesions 1 week after being stung by jellyfish. three patients had flare-up lesions after only one exposure to jellyfish. all of the recurring lesions were vesicular erythema, and the histological findings of case 3 corresponded to that of allergic contact dermatitis.20092868932
clostridial infection of renal cell carcinoma.we report a case of a large gas-filled clostridial abscess in a previously unrecognized renal cell carcinoma. neoplastic tissue has a nonhomogeneous blood supply, creating areas of hypoxia and reduced glucose concentrations, which lead to tumor necrosis and an environment conducive to the growth of anaerobic organisms. anaerobic infection should be considered in any patient with carcinoma and fever. conversely, abscess transformation of a tumor can be the explanation for what otherwise seems to ...19862868130
studies on neurotransmitter markers and neuronal cell density in the cerebellar system in olivopontocerebellar atrophy and cortical cerebellar atrophy.glutamate, aspartate and gamma-aminobutyrate (gaba) concentrations and choline acetyltransferase (chat) activity were measured in postmortem cerebellar cortical areas and brainstem nuclei of 10 normal controls, 5 patients of olivopontocerebellar atrophy (opca) with multiple system atrophy (msa) and 2 patients of cortical cerebellar atrophy (cca). in addition, the neuronal cell density in the cerebellar cortex and the brainstem nuclei was determined, and the correlation between neurotransmitter m ...20102868072
involvement of gangliosides in rabies virus infection.the role of gangliosides in rabies virus infection of chick embryo-related (cer) cells was investigated. cultured cells were pretreated with neuraminidase to render the cells transiently non-susceptible to viral infection. incubation of these desialylated cells with gangliosides allowed them to incorporate exogenous gangliosides and they recovered their susceptibility to rabies virus infection. infection of cer cells was monitored by specific fluorescence 24 h after virus inoculation. the use of ...19862868068
expert system for pharmaceutical analysis. i. selection of the detection system in high-performance liquid chromatographic analysis: uv versus amperometric detection.the usefulness of amperometric detection in pharmaceutical analyses was investigated for different groups of drugs. the uv response at 254 nm and that at the absorption maximum of the solute were compared with the electrochemical signal obtained. the minimum detectable concentration (nanograms on-column) of each substance is reported for the three different detection systems. this comparison was performed for 72 drugs (local anaesthetics, antipyretics, tricyclic antidepressants, sulphonamides, s ...20102868023
regulation of protein synthesis in heat-shocked drosophila cells. soluble factors control translation in vitro.we have developed an in vitro translation system from heat-shocked and normal drosophila cultured cells. the lysates retain regulation of translation typical of the whole cells from which they were prepared, both when programmed by endogenous mrna and when rna-dependent. these systems have been used to investigate the mechanism of shutdown of normal protein synthesis and selection of heat shock mrnas for translation in heat shock in drosophila. supplementation of intact rna-dependent lysates wit ...20102868010
action of excitatory amino acids and their antagonists on hippocampal neurons.intracellular recordings were obtained from guinea pig hippocampal neurons maintained in vitro. current- and voltage-clamp techniques were used to study the effect of microiontophoresis of excitatory amino acid agonists. modification of agonist responses by bath application of known concentrations of antagonist agents was also examined. all agonists used, glutamate, aspartate, n-methyl-d-aspartic acid (nmda), and quisqualate, depolarized hippocampal neurons and caused repetitive firing. nmda was ...19852867826
the effect of mixed-function oxidation of enzymes on their susceptibility to degradation by a nonlysosomal cysteine proteinase.mixed-function oxidation of escherichia coli glutamine synthetase by ascorbate, oxygen, and iron has previously been shown to cause inactivation of the enzyme and enhanced susceptibility to proteolytic attack by a variety of proteases. one of these proteases, from rat liver, is a high molecular weight cysteine proteinase which does not degrade native glutamine synthetase at neutral ph. although inactive, the oxidized glutamine synthetase preparations used in this study were only partially degrad ...19852867745
acute transverse myelopathy. 20102867265
antihypertensive therapy: newer concepts and agents.major advances have taken place in recent years with respect to our understanding of hypertensive diseases, the mechanisms of action of other therapeutic agents, and the introduction of new classes of drugs. standard therapy today uses the basic of employing nonpharmacological modalities. thereafter a stepped-care program with pharmacological entities has been advocated using diuretic, antiadrenergic, and vasodilating agents. however, new modes of action have been introduced therapeutically duri ...20092866842
myc oncogene activation in b and t lymphoid tumours.the chromosome translocations characteristic of certain b lymphoid tumours associate the myc oncogene and immunoglobulin loci. the typical t(12;15) in murine plasmacytomas and analogous t(14;8) in burkitt lymphomas couple the myc coding region to one of the switch recombination regions within the immunoglobulin heavy (h) chain locus; hence the switch machinery may promote some translocations. significantly, translocation induces constitutive myc expression, the untranslocated myc allele remainin ...20092866524
myc oncogene activation in b and t lymphoid tumours.the chromosome translocations characteristic of certain b lymphoid tumours associate the myc oncogene and immunoglobulin loci. the typical t(12;15) in murine plasmacytomas and analogous t(14;8) in burkitt lymphomas couple the myc coding region to one of the switch recombination regions within the immunoglobulin heavy (h) chain locus; hence the switch machinery may promote some translocations. significantly, translocation induces constitutive myc expression, the untranslocated myc allele remainin ...20092866524
[changes in erythrocytes in malignant neoplasms]. 20102866483
[the role of the nurse in starting beta-blocker therapy]. 20092865817
sarcoidosis of the nervous system. 20102865523
effect of excitatory amino acids and analogues on [3h]acetylcholine release from amacrine cells of the rabbit retina.the pharmacology of cholinergic amacrine cells has been further studied by examining the effects of excitatory amino acids and antagonists on [3h]acetylcholine (ach) release from the retinas of anaesthetized rabbits. exposure of the retina to glutamate (5 mm), aspartate (5 mm), kainate (8 microm) and quisqualate (8 microm) abolished the light-evoked release of [3h]ach but increased the spontaneous resting release four- to fivefold. n-methyl-d-aspartate (nmda) (5 mm) in normal krebs bicarbonate m ...19852865360
antidotal efficacy of isopropamide iodide in acute fluostigmine poisoning in mice. 20102864706
[synthesis and properties of an affinity adsorbent for purifying neuraminidases of varying origins].neuraminidases (na) from clostridium perfringens, noncholera vibrios and influenza virus were purified by affinity chromatography on sepharose coupled to para-aminophenyl oxamic acid. adsorption was carried out at ph 5.5. the effect of elution conditions on purification of na was studied. the use of the ph gradient enhances 10-fold the purification degree as compared with the ph shift-elution process, 90% of the activity being eluted from the column within a ph range from 6.0 to 6.6. according t ...19852864684
fire walking. 20102864675
neurohumoral vasoconstrictor systems in heart failure.by means of specific inhibitors of the renin-angiotensin system (captopril) and of the sympathetic nervous activity (prazosin) in dogs with congestive heart failure, and by using a specific antagonist of the pressor activity of arginine vasopressin in rats with heart failure, we studied the influence of these pressor hormone systems on peripheral vascular resistance and cardiac function. all three humoral vasoconstrictor systems were stimulated in heart failure. the experiments in dogs showed th ...19852864248
[changes in acetylcholine contractions induced by carnitine in coronary vessels isolated "in vitro"].as suggested by literature about the carnitine's choline-mimetic effects, it has been studied the influence of this substance on the response to ach of the isolated coronary arteries. it has been seen that ach has often induced the contraction of the preparation that was preceded or abolished by atropine or prifinium bromide, or reduced by fendiline and verapamil. it resulted also that carnitine has always increased the entity of the contraction of the preparation treated with ach and that the r ...19852863965
[the saprophytic phase in the ecology of the causative agents of infectious diseases]. 19852863907
the synaptic distribution of the retinal input in the superficial layers of the guinea-pig superior colliculus.an evoked potential consisting of four postsynaptic components was recorded in the guinea-pig superior colliculus following electrical stimulation of the contralateral optic nerve. this potential was generated in response to the activation of four populations of optic nerve fibres with different conduction velocities. current source-density analysis revealed that the two slower conducting fibre populations synapse in the upper third of the stratum griseum superficiale on dendrites whose cell bod ...19852863823
lav/htlv-iii antibodies in connective tissue diseases. 19852863569
standards, attitudes and accountability in the medical profession.as a spokesperson for a british patient advocacy group, action for the victims of medical accidents (avma), the author outlines the aims of the organization and the factors contributing to unsatisfactory resolution of cases involving such accidents. he points out that 70% of the clients of avma seek a good explanation of what happened rather than compensation. accountability in the medical profession is inadequate, and care often comes to a halt when something goes wrong because no one wants to ...20102863554
enzyme-based salicylate estimation. 20102863533
detection of infectious htlv-iii/lav virus in cell-free plasma from aids patients. 19852863528
possible role of insulin deficiency and growth hormone in severe retinopathy. 20102863521
undertreatment and asthma deaths. 20102863518
transient neonatal hypothyroidism in very low birthweight infants: is treatment necessary? 20102863505
prospective study of acquisition of cryptosporidium, giardia lamblia, and gastrointestinal illness. 19852863502
importance of highly sensitive serological tests for cytomegalovirus in bone marrow transplant patients. 19852863463
6,7-dihydro-5-[[(cis-2-hydroxy-trans-3-phenoxycyclopentyl)amino] methyl]-2-methylbenzo[b]thiophen-4(5h)-one: a novel alpha 1-adrenergic receptor antagonist and renal vasodilator. 19852863377
lymphatic transport of sodium cefoxitin in the presence of sodium 5-methoxysalicylate after injection into rat rectal connective tissue, femoral muscle and femoral vein.lymphatic uptake of sodium cefoxitin after injection into rectal connective tissue was greater than after injection into the femoral muscle of rats. coadministration with sodium 5-methoxysalicylate enhanced lymphatic drug uptake at both sites. this enhancement may be an indirect result of 5-methoxysalicylate's suppression of vascular permeation of the cefoxitin. an adjuvant-induced increase in lymphatic fluid flow may also be partially involved in the enhancement of cefoxitin lymphatic transport ...19852863362
protein phosphatases active on acetyl-coa carboxylase phosphorylated by casein kinase i, casein kinase ii and the camp-dependent protein kinase.the protein phosphatases in rat liver cytosol, active on rat liver acetyl-coa carboxylase (acc) phosphorylated by casein kinase i, casein kinase ii and the camp-dependent protein kinase, have been partially purified by anion-exchange and gel filtration chromatography. the major phosphatase activities against all three substrates copurify through fractionation and appear to be identical to protein phosphatases 2a1 and 2a2. no unique protein phosphatase active on 32p-acc phosphorylated by the case ...19852862868
protein phosphatases active on acetyl-coa carboxylase phosphorylated by casein kinase i, casein kinase ii and the camp-dependent protein kinase.the protein phosphatases in rat liver cytosol, active on rat liver acetyl-coa carboxylase (acc) phosphorylated by casein kinase i, casein kinase ii and the camp-dependent protein kinase, have been partially purified by anion-exchange and gel filtration chromatography. the major phosphatase activities against all three substrates copurify through fractionation and appear to be identical to protein phosphatases 2a1 and 2a2. no unique protein phosphatase active on 32p-acc phosphorylated by the case ...19852862868
effect of vector on infectivity of trypanosoma cruzi.a comparative study was carried out on the interaction between triatoma infestans and bloodstream forms (bsf) of trypanosoma cruzi isolates ra and up, both lethal for mouse, and ca-i nonlethal for this host. parasite duplication was readily detected in triatomes fed with ca-i, metacyclic (mtc) differentiation reaching a maximum at an optimum ingestion level of 250 bsf/insect. progress and differentiation proved much lower for ra, but reached intermediate values for the up isolate. assays for inf ...19852862777
effect of vector on infectivity of trypanosoma cruzi.a comparative study was carried out on the interaction between triatoma infestans and bloodstream forms (bsf) of trypanosoma cruzi isolates ra and up, both lethal for mouse, and ca-i nonlethal for this host. parasite duplication was readily detected in triatomes fed with ca-i, metacyclic (mtc) differentiation reaching a maximum at an optimum ingestion level of 250 bsf/insect. progress and differentiation proved much lower for ra, but reached intermediate values for the up isolate. assays for inf ...19852862777
[pathogenesis, clinical aspects and diagnosis of the most important enteric bacterial diseases in animals].there are adhesive and invasive species among enteropathogenic bacteria for animals. most frequently isolated adhesive bacteria are enterotoxigenic e. coli (etec). salmonella, t. hyodysenteriae, m. paratuberculosis, y. enterocolitica, cl. perfringens and c. jejuni bacteria represent the most important invasive germs. the main clinical finding connected with bacterial enteritis is diarrhoea resp. dysentery. evaluation of feces consistency, time of appearance and accompanying symptoms (e.g. fever, ...19852862716
non-o1 vibrio cholerae produces two newly identified toxins related to vibrio parahaemolyticus haemolysin and escherichia coli heat-stable enterotoxin. 19852862364
comparative evaluation of three identification systems for anaerobes.the accuracy of two new 4-h identification systems for anaerobes, the an-ident (analytab products, plainview, n.y.) and the rapid ana (innovative diagnostic systems, inc., atlanta, ga.) was compared with that of the api 20a system (analytab products). a total of 132 clinical isolates were tested in each of the three systems. the overall accuracies at the genus and species level for the three systems were: api 20a, 68.9 and 56.8%, respectively; an-ident, 90.2 and 73.5%; and rapid ana, 93.9 and 81 ...19852862161
neuraminidase activity is not the cause of influenza virus-induced neutrophil dysfunction.influenza viruses have been shown to decrease the ability of polymorphonuclear leukocytes (pmn) to respond to a variety of stimuli. this study was done to determine if viral neuraminidase was responsible for decreased pmn function. treatment of human pmn with purified neuraminidases from influenza virus, vibrio cholerae, or clostridium perfringens did not significantly affect the ability of human pmn to respond to stimulation. occasional virus preparations that lacked the ability to depress pmn ...19852862160
gamete intra-fallopian transfer (gift): a new treatment for infertility. 20102862118
anticholinergic drugs in the treatment of airways disease. 20102861843
photolabeling of mitochondrial f1-atpase by an azido derivative of the oligomycin-sensitivity conferring protein.an azido derivative of the oligomycin sensitivity conferring protein (oscp) was prepared by alkylation with the bifunctional reagent p-azido phenacyl bromide. azido-oscp was fully biologically active in the dark. upon photoirradiation of a mixture of beef heart mitochondrial f1-atpase and azido-oscp, the resulting covalent photoproducts were separated by polyacrylamide gel electrophoresis in the presence of na dodecyl sulfate and characterized by an immunochemical procedure. oscp was found to re ...19852861814
poor sulphoxidation in primary biliary cirrhosis. 20102861427
inactivation by wet and dry heat of aids-associated retroviruses during factor viii purification from plasma. 20102861402
rapid diagnosis of campylobacter-associated gastritis. 19852861379
effect of phenobarbital on the gamma-glutamyltranspeptidase activity and the remodeling of nodules induced by the initiation-selection model.the effect of subsequent administration of phenobarbital on the gamma-glutamyltranspeptidase (ggt) activity and on the remodeling of nodules induced by the solt-farber procedure was examined in rats. ggt-nodules were initiated by diethylnitrosamine (dena) followed by selection with 2-acetylaminofluorene (2aaf) in the diet and a partial hepatectomy (ph). phenobarbital (500 ppm in the drinking water), administered to rats that were previously treated according to the solt-farber procedure, (1) inc ...19852860967
[combined propyphenazone and codeine poisoning in childhood (analysis of 6 patients with spasmoplus poisoning)].the case histories are presented of 6 patients with accidental poisoning by spasmoplus suppositories. the main toxic constituents are codeine and the pyrazolone derivative, propyphenazone. all patients had symptoms of codeine intoxication with somnolence, miosis and oedema, 2 patients had also symptoms of prophyphenazone intoxication with hypotension, coma and convulsions. 1 patient died during the acute stage in a state of shock, with arrhythmia, and asystole.20092860755
[combined propyphenazone and codeine poisoning in childhood (analysis of 6 patients with spasmoplus poisoning)].the case histories are presented of 6 patients with accidental poisoning by spasmoplus suppositories. the main toxic constituents are codeine and the pyrazolone derivative, propyphenazone. all patients had symptoms of codeine intoxication with somnolence, miosis and oedema, 2 patients had also symptoms of prophyphenazone intoxication with hypotension, coma and convulsions. 1 patient died during the acute stage in a state of shock, with arrhythmia, and asystole.20092860755
functional morphology of the piper hyporhamphus ihi with reference to the role of the lateral line in feeding.as a basis for understanding the function of the halfbeak of the piper hyporhamphus ihi (phillips), details of the structure and dimensions of the anterior lateral line on the head and lower jaw of the piper are described. the anterior lateral line is composed of a series of cranial canals; the supraorbital-postorbital canal; the suborbital canal; and the preopercular-mandibular canal which extends along the lower jaw. each canal opens to the surface by a series of pores, and individual neuromas ...20102860672
[current status of kidney transplantation and results]. 20012860545
[improvement in the prognosis of rapid progressive glomerulonephritis by plasmapheresis treatment]. 19992860543
induction of vibrio cholerae specific biliary antibodies after oral immunisation with a cholera cell-wall fraction. 19852860476
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