Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [routine use of 6-month antitubercular treatment in 300 patients]. | over a 2-year period, all patients with incipient tuberculosis seen in a hospital unit were given a 6-month treatment consisting of rifampicine, isoniazide, pyrazinamide and ethambutol. a retrospective study of these 300 patients showed that the treatment was effective, with no failure if taken for more than 2 months. relapses were rare when the drugs were taken regularly, the responsible m. tuberculosis strain was sensitive, and there was no associated malignancy (present in 1.4% of the cases). ... | 2010 | 2954063 |
| cell surface sialic acid influences tumor cell recognition in the mixed lymphocyte reaction. | the ia+ b cell lymphoma, aktb-1b, fails to stimulate thymic lymphocytes in a one-way mixed lymphocyte reaction unless pretreated with sialidase or inhibitors of n-linked oligosaccharide processing. a comparison of different sialidases and sialyltransferases suggests that the removal of only a subset of total surface sialic acid, rather than net desialylation of the cell surface, is required. three sialidases were compared, including vibrio cholerae (vc) and clostridium perfringens (cp), which wi ... | 1987 | 2953814 |
| reiter's syndrome in an adolescent female with systemic sequelae. | reiter's syndrome (rs) generally affects adult white males. it occurs infrequently in adolescents. this condition is characterized by a triad of symptoms: arthritis, urethritis, and ocular abnormalities, and it usually has a benign course. we report an atypical case of rs in a black adolescent female who developed articular and ocular sequelae. despite aggressive medical therapy, one year after diagnosis her condition has deteriorated and she is confined to a wheelchair. although rs is believed ... | 2010 | 2953700 |
| interactions of monomeric igg bearing covalently bound c3b with polymorphonuclear leucocytes. | the interactions of monomeric igg, monomeric c3b, dimeric c3b, and c3b covalently bound to igg (c3b-igg) with neutrophils were examined. c3b-igg heterodimers exhibited an increased affinity of binding to neutrophils, relative to c3b, both at half normal ionic strength (five-fold enhancement) and at normal ionic strength (six-fold enhancement). binding of monomeric igg to neutrophils was barely detectable and did not permit direct measurements of affinity in our assay conditions. the increased af ... | 2010 | 2953672 |
| [diagnostic and therapeutic interventions in extrauterine pregnancy]. | between 1969 and 1985 surgery was performed in 456 cases of extrauterine pregnancy (eup) at tübingen university gynecological clinic. the average number of such operations performed annually rose from 11 in the first six years to 61 in the last three years. as a result of early detection and treatment of eup, tubal ruptures and severe intraabdominal hemorrhages have become increasingly rare. in the last six years, blood transfusions were only necessary in 6% of the patients who underwent surgery ... | 2010 | 2953643 |
| hyperthyroidism selectively increases oxidative metabolism of slow-oxidative motor units. | the effects of thyroid hormone on the nadh-tetrazolium reductase activity (oxidative metabolism marker) of soleus (slow-oxidative) and tensor fascia lata (fast-glycolytic) motoneurons were determined and compared with changes in a variety of enzyme activities in the corresponding muscle fibers. histochemical assays have demonstrated a selective and qualitative conversion in muscle fiber atpase and quantitative increases of nadh-tetrazolium reductase (oxidative) and mitochondrial alpha-glyceropho ... | 1987 | 2953623 |
| prolongation of graft survival in als-treated mice by donor-specific bone marrow. density gradient fractionation of the active bone marrow cells. | antilymphocyte serum (als)-treated recipient mice that are infused with donor bone marrow cells have been shown to enjoy prolonged skin graft survival. in the present experiments, discontinuous density gradient centrifugation in percoll was used to prepare fractions of these cells. two of four fractions had good graft-prolonging ability. in experiments in which the density of the gradients was varied, we were able to estimate the density of a major portion of the cells active in graft prolongati ... | 2010 | 2953092 |
| a maternal mrna localized to the animal pole of xenopus eggs encodes a subunit of mitochondrial atpase. | we have previously isolated several cdna clones of mrnas that have the unusual property of being localized to either the animal pole or the vegetal pole of frog eggs. to gain insight into the function of these maternal mrnas we have determined their dna sequence and deduced the sequence of the proteins they encode. here we report that an2, an mrna localized to the animal pole of xenopus oocytes and eggs, codes for the alpha chain of mitochondrial atpase. furthermore, we compare the intracellular ... | 2010 | 2953029 |
| [unexplained dyspnea in systemic diseases. importance of bronchiolo-alveolar lavage]. | 1987 | 2953017 | |
| possible role of helper and cytolytic t cells in mycobacterial infections. | 1986 | 2952852 | |
| dose measurements in photodynamic therapy of cancer. | a theory and method for prediction and measurement of the effective absorbed dose in photodynamic therapy of cancer is presented. the method depends on measuring the concentration of the photosensitizer (such as dihematorporphyrin ether), the flux density of the light, and the relative photodynamic effectiveness. previous, less exact methods relied on specifying the drug dosage and delay after injection and or the irradiance at the surface or power from an interstitial fiber. the new formulation ... | 2010 | 2952849 |
| a syngeneic mlr induced in vivo results in t-cell mediated immune suppression. | the proliferation of murine t lymphocytes in response to syngeneic ia bearing non-t cells (syngeneic mixed lymphocyte reaction, smlr) has been shown to generate regulatory t cells in vitro. an in vivo regulatory role has therefore been proposed for the smlr. to study this role more directly, we examined the effects of repeated iv injection of mice with activated syngeneic b cells. three such weekly injections induced a suppression of the plaque forming cell response to a subsequent injection of ... | 2010 | 2952287 |
| isolation and analysis of escherichia coli mutants that allow increased replication of bacteriophage lambda. | escherichia coli mutants were isolated that supported the growth of a lambda ots and, in at least one case, a lambda bts phage at the normally nonpermissive temperature of 39 degrees c. in one such strain, ots and bts suppression ability appeared to be a function of the guab gene. ots suppression by the mutant guab strain was prevented if high levels of guanine or xanthine were present in the medium. no other base had any effect on ots suppression in this strain. other strains carrying spontaneo ... | 1987 | 2951367 |
| brain beta-endorphin and spinal-cord enkephalin concentrations in experimental arachnoiditis. | arachnoiditis was produced experimentally in male albino icr mice by intrathecal injection of meglumine iocarmate . a control group received intrathecal injection of an electrolyte solution resembling csf. eight weeks after injection, the brains and spinal cords were removed for brain beta-endorphin and spinal cord met-enkephalin measurement by radioimmunoassay, and the dural sacs were removed for histologic examination to confirm the presence or absence of arachnoiditis. brain beta-endorphin co ... | 2010 | 2951348 |
| hypoglycaemia and criminal responsibility: a guide to a lawyer's view of diabetes. | 2010 | 2951200 | |
| the effect of six months continuous subcutaneous insulin infusion on kidney function and size in insulin-dependent diabetics. | glomerular filtration rate (gfr), renal plasma flow (rpf), kidney volume, and urinary albumin excretion rate were measured in 24 insulin-dependent diabetics, aged 29 +/- 7 years (mean +/- s.d.) of 8 +/- 4 years duration, randomly allocated to either continuous subcutaneous insulin infusion (csii) (n = 12) or unchanged conventional insulin treatment (cit) (n = 12). glomerular filtration rate, renal plasma flow, and kidney volume were identical in the two groups at the start of the study, although ... | 2009 | 2951131 |
| biological properties of htlv-iii/lav: a possible pathway of natural infection in vivo. | 1986 | 2950906 | |
| [results of examining the population in a region with high morbidity for oral mucosal cancer: precancerous changes]. | interviewing and examination of a population characterized by a high level of morbidity of oral cavity cancer, supposedly induced by the use of nas, established a high incidence of leukoplakia and preleukoplakia at this site which are identified as precancerous lesions. the highest relative risk of oral cavity leukoplakia was found in persons who both chew nas and smoke tobacco (12.4). relative risk of leukoplakia is also elevated in those who either chew nas (5.6) or smoke cigarettes (7.7). thi ... | 1987 | 2950660 |
| [emergency and necessity of thrombolysis in acute massive pulmonary embolism]. | 2010 | 2950458 | |
| [the other heparin cofactor]. | 2010 | 2950443 | |
| [toward a decrease in the use of oral cholecystography and intravenous cholangiography]. | 2010 | 2950439 | |
| [clinical interpretation of retinal circulatory measurements. i. technical measurement possibilities and clinical interpretation aid]. | the present possibilities to measure blood flow and other magnitudes of retinal microcirculation in vivo are discussed. on this basis, a simple model designed for retinal microcirculation is presented as a tool for the clinical interpretation of measuring results. based on the experience of over 200 measurements of retinal microcirculation magnitudes, subsequent reports give a clinical interpretation of measuring results, utilizing the measuring models presented. thus, it is intended to demonstr ... | 2010 | 2950360 |
| [drinking water legislation and its problems for the public health service]. | 2010 | 2950356 | |
| [working with obese children and adolescents in the youth public health service. students]. | 2010 | 2950353 | |
| different neuronal location of [3h]sch 23390 binding sites in pars reticulata and pars compacta of the substantia nigra in the rat. | the precise neuronal localization of d1 receptors in the substantia nigra has been studied autoradiographically in the rat by measuring the alterations of [3h]sch 23390 binding site densities in this brain area after 6-hydroxydopamine (6-ohda) induced destruction of nigrostriatal dopaminergic neurons and after ibotenate-induced lesion of striatal afferents. 6-ohda-induced nigral lesion provoked a total loss of [3h]sch 23390 binding sites in the pars compacta and pars lateralis (but not in the pa ... | 1986 | 2950341 |
| a comparison of skin preparation procedures for accessing implanted ports. | 2010 | 2950340 | |
| effects of dietary selenite, selenocystine and selenomethionine on selenocysteine lyase and glutathione peroxidase activities and on selenium levels in rat tissues. | weanling male rats were fed a basal selenium (se)-deficient diet or this diet plus 2 ppm se as either selenite, selenocystine (secys) or selenomethionine (semet) for 9 wk. the rats were killed by decapitation while anesthetized with ether, and tissues were assayed for glutathione peroxidase (gpx) and selenocysteine lyase activities, and for se content. dietary se had no effect upon the activity of tissue selenocysteine lyase. this activity was highest in the liver, followed by kidney, muscle and ... | 1987 | 2950214 |
| treatment of endometrial hyperplasia with cyproterone acetate histological and hormonal aspects. | a regime of cyproterone acetate (cpa) (300 mg/day by the oral route for 30 days) has been used in 10 post-menopausal women with endometrial hyperplasia (8 atypical and 2 adenomatous). androstenedione (a), estrone (e1), testosterone (t) and estradiol (e2) plasma levels were determined before and at the end of treatment. the regression of endometrial hyperplasia was ascertained histologically in all patients after 30 days of therapy. all steroids showed a significant decrease (p less than 0.05) as ... | 2010 | 2949483 |
| [tuberous iododerma due to solutan]. | 2010 | 2949449 | |
| regulation of autoimmune disease physiological and therapeutic. | an important question is how the immune system can control the behavior of autoimmune effector lymphocytes. my colleagues and i have investigated this question in four models. three models of organ specific autoimmune diseases were studied using the specific autoimmune lines or clones of t lymphocytes functionally involved in the disease process. the fourth model was an anti-idiotypic network triggered spontaneously by autoantibodies. this article reviews the evidence indicating that healthy ind ... | 2010 | 2948901 |
| characterization of (ca2+ + mg2+)-atpase of sarcoplasmic reticulum by laser-excited europium luminescence. | the molecular environment of ca2+ translocating sites of skeletal muscle sarcoplasmic reticulum (sr) (ca2+ + mg2+)-atpase has been studied by pulsed-laser excited luminescence of eu3+ used as a ca2+ analogue. interaction of eu3+ with sr was characterized by investigating its effect on partial reactions of the ca2+ transport cycle. in native sr vesicles, eu3+ was found to inhibit ca2+ binding, phosphoenzyme formation, atp hydrolysis activity and ca2+ uptake in parallel fashion. the non-specific b ... | 1987 | 2948822 |
| [aspects of local secretory immunity, determined in the saliva, during physiologic pregnancy]. | 2010 | 2948240 | |
| ultrastructural changes in the sarcoplasmic reticulum in acute myocardial ischemia. | we investigated the morphologic changes in the sarcoplasmic reticulum (sr) in acute myocardial ischemia, induced by occlusion of the coronary artery in the canine heart, by freeze-fracture of sr in situ and in vitro, and they were compared to the alterations in ca++-stimulated atpase activity and protein composition of the isolated sr. both sr in situ and the isolated sr exhibited typical intramembranous particles with diameters of 70 to 90 a in freeze-fracture replicas. the intramembranous part ... | 1986 | 2948034 |
| collateral circles in carotid artery occlusion. a comparative study between cw doppler and contrast angiography. | 2010 | 2947984 | |
| the gene for the atrial natriuretic factor is expressed in the aortic arch. | the gene for atrial natriuretic factor is expressed within the adventitial cells of the rat aortic arch. atrial natriuretic factor transcripts, similar in overall size (1100-1200 nucleotides) and 5'-termini to those found in the atria, were identified in the arch. much lower levels (approximately 10-20%) of these transcripts were present in distal thoracic aorta. atrial natriuretic factor peptide was localized by immunocytochemistry to the adventitia of the arch in regions thought to harbor the ... | 1987 | 2947852 |
| [the ovarian vein syndrome]. | 2010 | 2947504 | |
| prevention of renoprival nephropathy. | 2009 | 2947383 | |
| class ii major histocompatibility complex and organ specific autoimmunity in man. | t helper lymphocytes only recognize the antigen to which they are directed if it is 'presented' to them by a cell expressing the same class ii major histocompatibility complex (mhc) antigen as themselves. since the target cells of most organ specific autoimmune diseases do not normally express class ii mhc proteins on their surface, any cell specific surface antigens they possess may never have been presented, and therefore immunological tolerance to them may not exist. the target cells in sever ... | 1986 | 2946837 |
| hla-linked nonresponsiveness to cryptomeria japonica pollen antigen. i. nonresponsiveness is mediated by antigen-specific suppressor t cell. | the objective of this study was to elucidate the cellular mechanism of ige nonresponse to the cryptomeria japonica (japanese cedar) pollen antigen (cpag), which was shown in our previous study to be hla-linked (1). we established an assay system for the measurement of small amounts of anti-cpag ige antibody, both in an antigen-specific and isotype-specific manner, and a culture system to induce antigen-driven ige antibody synthesis in vitro. by using these methods, we clarified that the function ... | 2010 | 2946774 |
| characterization of two monoclonal idiotype-binding suppressor t cell factors specific for the antibody response to l-glutamic acid60-l-alanine30-l-tyrosine10 (gat). | we have previously identified and described two distinct types of suppressor t cell factors specific for the pfc response to l-glutamic acid60-l-alanine30-l-tyrosine10 (gat) or l-glutamic acid50-l-tyrosine50 (gt). both of these factors are antigen-specific and i-j+. gat-tsf1 is not mhc-restricted and is composed of a single polypeptide chain, whereas gat-tsf2 is mhc-restricted and is composed of two different polypeptide chains. we have not previously found evidence for an obligatory, idiotype-s ... | 2010 | 2946767 |
| biosynthesis of sulfated asparagine-linked oligosaccharides on bovine lutropin. | the asparagine-linked oligosaccharides on bovine lutropin (blh) are unusual, containing galnac and sulfate but no galactose or sialic acid. oligosaccharides from metabolically radiolabeled or purified blh consist of non- (neutral), mono- (s-1), and di- (s-2) sulfated structures. we have previously shown that s-2 is a complex type oligosaccharide bearing two peripheral branches with the sequence so4----galnac----glcnac attached to a typical man3glcnac2 core (green, e.d., van halbeek, h., boime, i ... | 1986 | 2946684 |
| structure-activity relationships of sex steroid analogs determined in vitro in a thyroid hormone-responsive membrane ca2+-atpase model. | physiological concentrations of l-t4 were found previously to stimulate ca2+-atpase activity in vitro in reticulocyte membranes from female rabbits and to inhibit this enzyme in reticulocyte membranes from males. in these previous studies, preincubation of intact cells or ghosts with testosterone (5 x 10(-11) m) converted female-source reticulocyte membranes to male-type responsiveness to thyroid hormone (inhibition of ca2+-atpase activity). preincubation of reticulocyte membranes with 17 beta-e ... | 1986 | 2946570 |
| structure-activity relationships of sex steroid analogs determined in vitro in a thyroid hormone-responsive membrane ca2+-atpase model. | physiological concentrations of l-t4 were found previously to stimulate ca2+-atpase activity in vitro in reticulocyte membranes from female rabbits and to inhibit this enzyme in reticulocyte membranes from males. in these previous studies, preincubation of intact cells or ghosts with testosterone (5 x 10(-11) m) converted female-source reticulocyte membranes to male-type responsiveness to thyroid hormone (inhibition of ca2+-atpase activity). preincubation of reticulocyte membranes with 17 beta-e ... | 1986 | 2946570 |
| symptoms in relation to the level of spondylolysis. | spondylolysis usually occurs in the fifth lumbar vertebra, which with the rest of the lumbosacral junction may be hypoplastic. about 10% of spondylolysis occurs in the fourth lumbar vertebra which is usually normal radiologically. the present work studies the hitherto unknown prognostic value of the lysis level in relation to symptoms. a comparison was made between 213 patients with lysis at l5 and 42 patients with lysis at l4. the frequency and intensity of low back pain, the need for treatment ... | 2010 | 2945791 |
| interaction studies in mice of sch 29851, a potential non-sedating antihistamine, with commonly used therapeutic agents. | sch 29851 was studied for its ability to interact with selected drugs used in man. the non-sedating antihistamine terfenadine and the sedating antihistamine diphenhydramine were also studied for comparison. sch 29851 at 80 mg/kg po in mice, a dose about 50 times its ed50 for blocking histamine-induced paw edema in the same species, potentiated the anticonvulsant effects of diazepam. at the high dose of 320 mg/kg po, about 80 times its ed50 for antihistamine effects, sch 29851 potentiated the abi ... | 1986 | 2945410 |
| h-2-linked genes determine the level of the primary in vitro anti-mls response. | the level of cell proliferation and interleukin-2 (il-2) production observed in an anti-mls mixed lymphocyte reaction between spleen cells from h-2 compatible, mls incompatible mouse strains is determined by the h-2 haplotype of the mouse combination. thus, while akr (h-2k) spleen cells stimulated strong mlsa responses in h-2k responder cells, akr-h-2b spleen cells stimulated no or negligible mlsa responses in responder cells from h-2b mouse strains. this effect was observed at the levels of il- ... | 1986 | 2944823 |
| merits and pitfalls in morphological assessment of cardiac growth. | the basic principles of quantitative morphological analysis of myocardial tissue are presented. particular attention is paid to the effects of stimulated cardiac growth on the relationship between cell size and various indices of myocardial capillary supply in pressure-overloaded rat hearts. the importance of adequate sampling and of the number of measurements is stressed with respect to reliable estimation of the mean values but even more for assessment of variability of the measured data. when ... | 1986 | 2944767 |
| merits and pitfalls in morphological assessment of cardiac growth. | the basic principles of quantitative morphological analysis of myocardial tissue are presented. particular attention is paid to the effects of stimulated cardiac growth on the relationship between cell size and various indices of myocardial capillary supply in pressure-overloaded rat hearts. the importance of adequate sampling and of the number of measurements is stressed with respect to reliable estimation of the mean values but even more for assessment of variability of the measured data. when ... | 1986 | 2944767 |
| control of hidradenitis suppurativa in women using combined antiandrogen (cyproterone acetate) and oestrogen therapy. | the effects of combined treatment with the antiandrogen, cyproterone acetate, and ethinyl oestradiol on four women with long-standing hidradenitis suppurativa have been investigated. the condition was controlled successfully in all patients with 100 mg/day cyproterone acetate using the reversed sequential regimen; lowering the antiandrogen to 50 mg/day caused deterioration. before treatment, plasma testosterone levels were within the normal range, but plasma androstenedione values were raised an ... | 2010 | 2944535 |
| ige receptors on inflammatory cells: the role of ige complexes in food allergy. | 2010 | 2944469 | |
| [plasmapheresis in the complex therapy of patients with acute pyelonephritis and urologic infection]. | in 19 urological patients with pyointoxication and urosepsis 49 plasmaphereses for the purpose of detoxication were performed in the complex with other therapeutic measures. the causes for the pyoseptic complications were as follows: urolithiasis in connection with acute pyelonephritis, acute pyelonephritis (among others in pregnancy, cystic renal dysplasia, carcinoma of the urinary bladder), renal insufficiency in the terminal stage. the treatment of these diseases with haemodialysis and haemop ... | 2010 | 2944310 |
| preliminary observations on lungworms in farmed and feral red deer (cervus elaphus) in denmark. | deer farming is on its increase in denmark. based on experiences from other countries, lungworm infection is expected to cause severe problems in farmed deer. therefore, in the present paper, which is the first one to deal with pathogens in danish deer farms, the faecal larval excretion in red deer is examined. | 1986 | 2944072 |
| effect of boiled-rice feeding in childhood cholera on clinical outcome. | forty-eight children, aged 2-5 years, presenting with watery diarrhoea of less than 48 h duration at home prior to hospitalization, were admitted into a randomized controlled clinical trial, 24 children being treated during the first 24 h of admission with oral rehydration solution (ors) alone and 24 children being given 'ors plus boiled-rice feeding'. the latter group received boiled-rice to supply at least 55 kcal/kg/d (about 150 g boiled-rice per feed, given four times daily). vibrio cholerae ... | 1986 | 2943703 |
| effects of cadmium on the uptake of dopamine and norepinephrine in rat brain synaptosomes. | 1986 | 2943340 | |
| the (ca2+ + mg2+)-stimulated atpase of the rat parotid endoplasmic reticulum. | a membrane fraction enriched in endoplasmic reticulum was prepared from rat parotid glands by using sucrose-gradient centrifugation. the fraction showed a 10-fold increase in specific activity of nadph: cytochrome c reductase activity over that of tissue homogenates and minimal contamination with plasma membranes or mitochondria. the endoplasmic reticulum fraction possessed both mg2+ -stimulated atpase as well as ca2+, mg2+-atpase [( ca2+ + mg2+)-stimulated atpase]activity. the ca2+, mg2+-atpase ... | 1986 | 2943271 |
| abnormal systolic time intervals in obesity and their relationship with the amount of overweight. | we studied 17 severely obese subjects (age range 26 to 42 years), without hypertension, diabetes mellitus, angina, or clinical signs of heart failure or respiratory disease, and 16 age-matched control subjects. x-teleroentgenographic findings (transverse cardiac diameter and cardiothoracic ratio), blood pressure, and mechanocardiographic parameters were analyzed in both groups. by means of conventional simultaneous recordings of ecg, phonocardiogram, and carotid pulse (100 mm/sec), systolic time ... | 2010 | 2943149 |
| [gene mutation and transfer caused by plasmid rp4::mu in vibrio cholerae]. | 1985 | 2943082 | |
| dose-related effects of synthetic human beta-endorphin and naloxone on fed gastrointestinal motility. | in humans, plasma beta-endorphin levels rise during application of acute stressful stimuli (vertigo, cold pain, and transcutaneous electrical stimulation) that induce gut motor disturbances. whereas it is possible that circulating beta-endorphin participates in the mediation of these central effects on gut motility, its role cannot be established solely on the basis of changes in plasma levels. therefore, we designed the present study to investigate 1) the dose-related effects of intravenous syn ... | 1986 | 2942039 |
| the significance of selected variables in laminectomy length of stay. | factors affecting hospital length of stay of patients undergoing laminectomy were examined by replicating a study by sutcliffe and vincent. results were similar, indicating that hospital stays were longer for patients unemployed prior to admission and for those who lived alone, had previous medical diagnoses, and had a jackson pratt drain. amount of postoperative ambulation also affected length of stay. there were several limitations to the study, including failure to differentiate regarding the ... | 2010 | 2941502 |
| depression and physical illness among elderly general medical clinic patients. | in this study we conducted a resurvey at 33 months of elderly general medical clinic outpatients previously classified as depressed or not using the zung self-rating depression scale. resurvey results and review of medical records permitted characterization of the point prevalences of depression at the time of the initial and follow-up surveys, and identification of physical illness factors associated with depression. the point prevalences of depression were approximately equal (20%), although o ... | 2010 | 2941471 |
| some analyses of forgetting of pictorial material in amnesic and demented patients. | three experiments evaluating the rate of forgetting of pictorial stimuli in amnesic, demented, and normal control subjects are reported. when prolonged exposures of pictorial material were used to equate recognition performance after a 10-min delay, alcoholic korsakoff (ak) patients and patients with huntington's disease (hd) demonstrated normal rates of forgetting over a 1-week period. in addition to replicating previous findings with ak patients, these results are consistent with recent sugges ... | 2010 | 2941450 |
| the comparative in vitro activity of twelve 4-quinolone antimicrobials against enteric pathogens. | the minimal inhibitory concentrations (mics) of twelve 4-quinolone antimicrobials were determined for salmonella typhi (25), salmonella spp. (50), shigella spp. (50), campylobacter jejuni (100), vibrio cholerae (10), vibrio parahaemolyticus (10), yersinia enterocolitica (25), aeromonas hydrophila (25) and plesiomonas shigelloides (10). mics were determined using an agar dilution technique in mueller-hinton agar (oxoid, england) supplemented with 10% lysed horse blood. antibiotic containing plate ... | 1985 | 2941257 |
| complement, membrane glycoproteins, and complement receptors: their role in regulation of the immune response. | to determine the effect of complement on the normal antibody response we studied seven patients with genetically determined complement component deficiencies, guinea pigs deficient of c4 and c2, respectively, and two patients whose neutrophils and monocytes lack the c3bi receptor. patients deficient of early complement components (c4, c2, c3) have abnormal antibody responses to the t-cell-dependent antigen, bacteriophage phi x 174. complement-deficient guinea pigs (c4, c2) produce less antibody ... | 1986 | 2941194 |
| atrial natriuretic factor. | 2010 | 2940755 | |
| industrial airborne irritant or allergic contact dermatitis. | industrial airborne irritant or allergic contact dermatitis is commonly observed in many factories. examples of airborne irritants include fibres (such as fibreglass or rockwool), various kinds of dust particles (such as cement, slag, sludge, insulating foam, wood chips), acids and alkalis, gasses and vapours. airborne contact allergens are unequivocally numerous. the clinical symptoms of both irritant and allergic airborne contact dermatitis are reviewed. | 2007 | 2940059 |
| quantification of sperm motility by a turbidimetric assay. correlation to cellular respiration. | the turbidimetric method according to sokoloski et al. (fertil. steril. 28, 1337-1341, 1977) was used for quantitative measurement of the motility of washed bovine spermatozoa. the method is based on the registration of the increase in absorbance (a538) which is produced by spermatozoa entering the light path after run from the bottom of a photometer cuvette. this increase in absorbance is dependent on the amount of motile cells and their average velocity. the increase in absorbance related to t ... | 1986 | 2939829 |
| plasmid-mediated changes in virulence of vibrio cholerae. | the effects of several plasmids, including cloning vectors and r factors, on the virulence of vibrio cholerae ca401r were determined by measuring the dose-related diarrheal response in orally challenged infant mice. the plasmids were also examined for their effects on the colonization ability of strain ca401r by joint infection experiments with a spectinomycin-resistant ca401 strain as an internal standard. one v. cholerae r factor, pvh2, enhanced the diarrheal response, while r factors rts1 and ... | 1986 | 2939028 |
| enzyme markers for vibrio cholerae: identification of classical, el tor and environmental strains. | enzyme electrophoretic variants were studied in 49 strains of vibrio cholerae using zymovar analysis. the following seven enzymes were selected for use: alanine dehydrogenase (adh), isocitrate dehydrogenase (idh), malate dehydrogenase (mdh), phosphoglucomutase (pgm), glucosephosphate isomerase (gpi), 6-phosphogluconate dehydrogenase (6pgdh) and glucose-6-phosphate dehydrogenase (g6pdh). the results indicated the presence of three main groups defined chiefly by their gpi and 6pgdh variants. the f ... | 1985 | 2938309 |
| [epileptics and their oral health]. | 2010 | 2937970 | |
| diabetic enteroneuropathy. | 1985 | 2937948 | |
| cocaine increases natural killer cell activity. | the administration of epinephrine to humans increases natural killer (nk) cell activity and numbers. if endogenous catecholamines regulate nk cells, then their activity should be increased by cocaine, an agent that potentiates endogenous catecholamines. we investigated the in vivo effect of cocaine on nk cell activity and on the distribution of lymphocyte subsets, including nk cells. intravenous cocaine (0.6 mg/kg) produced a three- to fourfold increase in nk cell activity in peripheral blood. t ... | 1986 | 2937807 |
| comparison of some procedures detecting circulating immune complexes. | tests for circulating immune complexes were performed by means of 1) plain polyethylene glycol (peg) precipitation (pegprec), 2) immunoelectrophoresis of peg precipitates (iepp), 3) anti-antibody (aa) inhibition test with sera (aa-is), and 4) aa inhibition test with peg precipitates (aa-ipp). the tests were performed with 156 pathological sera from patients with myasthenia gravis, syphilis, adenocarcinomas of the gastrointestinal tract, rheumatoid arthritis and systemic lupus erythematosus, and ... | 2010 | 2937722 |
| arthroplasty via intermediate phalangectomy. partial or complete. | the intermediate phalangectomy is discussed as an alternative to resection of the head of the proximal phalanx when surgically addressing the hammered digit syndrome. its use in several other clinical settings is presented along with its contraindications and potential complications. | 2010 | 2937522 |
| anatomy of the digits. | digital surgery of the foot is performed on a regular basis. knowledge of the anatomy is of particular importance in order to appreciate the pathophysiology of the deformity. with this understanding, the surgeon can then address the problems at the appropriate level. | 2010 | 2937521 |
| minimal incision techniques for digital deformities. | we have presented basic minimal incision approaches to the more common digital deformities. we feel that with proper evaluation of the deformity and the patient, minimal incision surgery techniques give excellent long-term results with several advantages. these advantages include: less discomfort due to less surgical dissection. less need for internal fixation by careful use of compression dressings in the immediate postoperative period along with early ambulation. less disability. compression d ... | 2010 | 2937517 |
| inactivation of atrial natriuretic factor in blood. | tissue extracts of rat heart atria contain a family of peptides with natriuretic and vasorelaxant properties. it has been shown by others that inactivation of this atrial natriuretic factor may involve endogenous peptidases. the present experiments demonstrate that incubation in blood in vitro reduces the natriuretic activity of the factor. specifically, inactivation was associated with a white cell/platelet fraction, indicating that these blood elements may play a physiological role in the meta ... | 1985 | 2937512 |
| expression of normal myeloid-associated antigens by acute leukemia cells. | monoclonal antibodies that react with hematopoietic cells and their precursors in a stage and lineage restricted fashion were used in indirect immunofluorescence assays to examine leukemic cells from 105 pediatric age patients. the differentiative states of blasts from 42 patients with acute nonlymphocytic leukemia (anll) were defined by these antibodies. when these were compared to their morphologic and histochemical levels of differentiation as defined by the french-american-british (fab) clas ... | 2010 | 2937468 |
| i.v. sedation for conservative dentistry. a comparison of midazolam and diazepam. | midazolam and the emulsion formulation of diazepam were compared in a cross-over study in 50 patients undergoing out-patient conservative dentistry, with particular regard to sedation and the quality of recovery. both agents proved effective, but sedation was achieved more rapidly with midazolam (p = 0.001) and was more effective (p less than 0.02). significantly greater anterograde amnesia for the dental procedure (p less than 0.001) and a more rapid return to normal activities (p less than 0.0 ... | 2010 | 2937434 |
| percutaneous transluminal coronary angioplasty in unstable angina: comparison with stable angina. | percutaneous transluminal coronary angioplasty was performed in 25 patients with unstable angina and in a similar group of 25 patients with stable angina. the frequency of single, double, and triple vessel disease was identical in each group. technical success was achieved in 22 (81%) out of 27 attempts in those with unstable angina and in 14 (52%) out of 27 attempts in those with stable angina. vessel occlusion occurred in nine patients, necessitating emergency bypass surgery in four. there was ... | 2010 | 2937433 |
| [availability and rational use of essential drugs in the treatment of cancer]. | 2010 | 2937425 | |
| occupational chloracne--physical and emotional considerations. | 2010 | 2937418 | |
| comparative study of coronary vasodilator and cardiac effects of nitrendipine by use of isolated, blood-perfused dog heart preparations. | the coronary vasodilator and cardiac effects of 3-ethyl-5-methyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl) -3,5-pyridinedicarboxylate (nitrendipine, bay e 5009) were compared in isolated, blood-perfused sinoatrial (sa) node, atrioventricular (av) node and papillary muscle preparations of dogs with i.a. administration. in all preparations nitrendipine increased (coronary) blood flow. in sa node preparations nitrendipine reduced sinus rate but the reduction remained only about 13% of the basal va ... | 1986 | 2937413 |
| cnbr cleavage of the light chain of human complement factor i and alignment of the fragments. | the light chain and heavy chain of reduced and alkylated human complement factor i were purified by high-pressure gel-permeation chromatography. cnbr cleavage of factor i light chain yielded four major fragments, which were purified by gel filtration. n-terminal sequence analysis of the cnbr-cleavage fragments allowed identification of 200 of the approx. 240 amino acid residues of the light chain. an alignment is proposed, based on sequence analysis of peptides obtained after cleavage at arginin ... | 1986 | 2937401 |
| effects of m-cl-peroxy benzoic acid on glycolysis in saccharomyces cerevisiae. | concentrations of m-cl-peroxy benzoic acid (cpba) higher than 0.1 mm decrease the atp-content of saccharomyces cerevisiae in the presence of glucose in 1 min to less than 10% of the initial value. in the absence of glucose, 1.0 mm cpba is necessary for a similar effect. after the rapid loss of atp in the first min in the presence of glucose caused by 0.2 mm cpba, the atp-content recovers to nearly the initial value after 10 min. aerobic glucose consumption and ethanol formation from glucose are ... | 1985 | 2937383 |
| [regression of post-infarction parietal dyskinesia after percutaneous coronary angioplasty]. | normalisation of abnormal segmental wall motion is rarely observed after myocardial revascularisation by aorto-coronary bypass when the territory revascularised is the site of post-transmural infarction dyskinesia. in particular, normalisation of segmental wall motion is extremely rare when dynamic tests designed to detect potential for improvement (trinitrin test and post-extrasystolic potentiation) are negative. we present the case of a 41 year old man who had anterior and septal wall dyskines ... | 1985 | 2937380 |
| platelet deposition on vascular grafts. the accuracy of in vivo quantitation and the significance of in vivo platelet reactivity. | an in vivo platelet imaging system utilizing indium-111-labeled platelets and technetium-99m-labeled red cells was used to serially study and compare platelet deposition on autologous external jugular vein grafts, autologous arterial grafts, polytetrafluoroethylene (gore-tex) and two dacron (meadox and usci) small diameter (4mm) vascular grafts implanted end-to-end in canine carotid and femoral arteries. this method of quantitating platelet deposition was validated by correlating deposition meas ... | 1986 | 2937375 |
| surgical treatment of rhinophyma with the shaw scalpel. | we present our experience with the shaw scalpel in the treatment of a patient with extensive rhinophyma. the heated blade of the scalpel provides rapid maintenance of hemostasis with minimal tissue damage and thus allows for rapid and accurate removal of tissue. after removing the bulk of tissue with the shaw scalpel, the carbon dioxide laser and dermabrader are used to refine nasal contours. | 2010 | 2937366 |
| [aortocoronary bypass. development of technics and indications over a 10-year period]. | during the 1973-1983 period considerable changes have taken place in the techniques and indications of coronary bypass. in a homogeneous series of 3095 patients operated upon by the same group, changes in techniques have been: the introduction in routine coronary bypass of the membrane oxygenator which provides optimal biological conditions and the prolonged circulatory assistance so necessary to high risk patients, and the application to coronary bypass of microsurgical techniques enabling surg ... | 2009 | 2937040 |
| photoreactive neurohypophyseal hormone analogs: effects on transport processes in mammalian and amphibian epithelia. | the synthesis of the photoreactive neurohypophyseal hormone analog [3-(p-azidophenylalanine]arginine vasopressin [( phe(p-n3)3]avp is described. [phe(p-n3)3]avp exhibits a rat antidiuretic activity of 173 +/- 18 u/mg and a high binding affinity for the renal v2 vasopressin receptor in bovine kidney; an apparent dissociation constant kd of (1.3 +/- 0.2) x 10(-8) m was determined. in the toad bladder [phe(p-n3)3]avp was the most potent photoreactive vasopressin analog studied to date. it stimulate ... | 1986 | 2936596 |
| the training for and practice of percutaneous transluminal coronary angioplasty: results of two surveys. | in order to gain understanding of how percutaneous transluminal coronary angioplasty (ptca) is taught and practiced in the united states, two questionnaires were devised to survey all adult cardiology training programs and all adult cardiac catheterization laboratories in this country. of the 184 programs that responded to the training questionnaire, 102 (55%) teach ptca, usually in the form of fellowship training and especially as a specialized year, and less commonly in the form of a preceptor ... | 2010 | 2936457 |
| thromboxane synthetase inhibitors: design and synthesis of a novel series of omega-pyridylalkenoic acids. | 2010 | 2936112 | |
| [rehabilitation of patients with traumatic cataracts from agricultural injuries]. | 2009 | 2935769 | |
| minimal spinal hyperostosis with low-dose isotretinoin therapy. | skeletal abnormalities have been reported on numerous occasions in patients who have received high doses of vitamin a and its derivatives. recently, a new derivative, isotretinoin (accutane, hoffman-laroche, inc.), has become available for the treatment of cystic acne. ninety-six patients treated for a minimum of four months with low doses of this drug at two university centers have shown overall good to excellent clinical responses. however, ten of these patients have developed small pointed ex ... | 2010 | 2935510 |
| the effect of drugs on breathing during sleep. | we hope that the reader is impressed with the relatively limited amount of information available about the effects of drugs on breathing during sleep in both normal subjects and patients with sleep-disordered breathing. although more reports are appearing, well-controlled evaluations remain limited in number. we believe that this information gap will quickly close because it is now increasingly appreciated that either spontaneous or drug-induced breathing abnormalities measured during wakefulnes ... | 2010 | 2935357 |
| in vitro activity of ciprofloxacin combined with azlocillin. | a ciprofloxacin plus azlocillin broth microdilution checkerboard was evaluated against 125 aerobic gram-negative and gram-positive bacteria. synergism (sigma fic less than or equal to 0.5) occurred among 56% of pseudomonas aeruginosa, 30% of acinetobacter species, and 40% of staphylococcus aureus studied. antagonism (sigma fic greater than or equal to 2) was present in less than 1% of the organisms. | 1985 | 2935078 |
| differential depression of hypoglossal nerve activity by alcohol. protection by pretreatment with medroxyprogesterone acetate. | upper airway obstruction during sleep occurs more commonly in men than in women and has been treated with progestational agents with some success. alcohol ingestion exacerbates sleep apnea, and recent studies have established that alcohol depresses the respiratory motor activity to upper airway muscles more than that to the diaphragm, a response pattern that favors upper airway obstruction during inspiration. to investigate the possibility that progesterone provides some protection from this act ... | 1986 | 2935056 |
| cigarette smoking and down syndrome. | a matched case-control study of 100 mothers of down syndrome children, 100 mothers of children with other defects (defect controls), and 100 mothers of children with no defects (normal controls) was carried out. all infants were born in upstate new york in 1980 and 1981. matching was very close on maternal age for the normal controls but not for the defect controls. the risk ratios for the association of cigarette smoking around the time of conception with down syndrome was 0.58 (90% confidence ... | 2010 | 2934980 |
| echocardiographic evaluation of left ventricular function during coronary artery angioplasty. | balloon occlusion of a stenotic coronary artery during percutaneous coronary artery angioplasty provides a unique opportunity to study the effect of acute myocardial ischemia on left ventricular (lv) function. simultaneous m-mode and 2-dimensional (2-d) echocardiograms and a 6-lead electrocardiogram were recorded during 20 episodes of coronary artery occlusion and release in 12 patients. no patient had previous myocardial infarction and all had normal lv function by angiography. all patients had ... | 1986 | 2934968 |
| [horizontal laparotomy in biliary tract surgery]. | for operations on the biliary tract the transverse horizontal incision has the same advantages as the subcostal approach: strong abdominal wall, little influence on ventilation and wide access to the subhepatic region. but in addition, the abdominal wall nerves are preserved as much as possible, post-operative evisceration, it is occurs, can easily be repaired and subsequent surgery can be performed using the same route. | 2010 | 2934697 |
| [primary disability as a result of sequelae of injuries to the musculo-skeletal system]. | 2010 | 2934673 |