Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| assessment, management, and treatment planning for male adolescent sexual offenders. | adolescent sexual offenders are considered as a part of the larger group of emotionally disturbed youngsters. for purposes of clinical management, areas of overlap between the two groups are identified and issues specific to sexual offenders are delineated. ethical issues, preventive interventions, the risk of recidivism, and the special problems presented by incestuous offenders are discussed. | 2010 | 3067582 |
| assessment, management, and treatment planning for male adolescent sexual offenders. | adolescent sexual offenders are considered as a part of the larger group of emotionally disturbed youngsters. for purposes of clinical management, areas of overlap between the two groups are identified and issues specific to sexual offenders are delineated. ethical issues, preventive interventions, the risk of recidivism, and the special problems presented by incestuous offenders are discussed. | 2010 | 3067582 |
| the censorship of pornography: catharsis or learning? | contemporary research on pornography reveals an impasse between the models of catharsis and learning. preference for the latter by a recent government report is based on ideological rather than scientific considerations. the breakdown in the liberal tradition, current pornography research based on behaviorism, and two major theoretical problems are discussed. the interface among psychology, sociology, and literary criticism is suggested as a positive direction for understanding pornography; cens ... | 2010 | 3067580 |
| the censorship of pornography: catharsis or learning? | contemporary research on pornography reveals an impasse between the models of catharsis and learning. preference for the latter by a recent government report is based on ideological rather than scientific considerations. the breakdown in the liberal tradition, current pornography research based on behaviorism, and two major theoretical problems are discussed. the interface among psychology, sociology, and literary criticism is suggested as a positive direction for understanding pornography; cens ... | 2010 | 3067580 |
| physiological and behavioral aspects of stress in adolescence. | gonadal and adrenal hormone levels appear to be linked to the stressors experienced by young adolescents. adjustment problems were accompanied by a profile of lower gonadal steroids and higher adrenal androgen levels, primarily androstenedione. later gonadal maturation may be a result of stress suppressing the reproductive axis. higher levels of androstenedione may be indicative of chronic levels of stress. however, the findings for androstenedione are complicated by the fact that androstenedion ... | 1988 | 3067560 |
| sympathoadrenal medullary system and stress. | 2011 | 3067552 | |
| dopamine-regulated protein phosphorylation in the basal ganglia. | 2011 | 3067550 | |
| psychochemistry in psychiatry. papers presented in memory of ole j. rafaelsen. | 2011 | 3067535 | |
| psychiatric and social problems among immigrants. | high rates of mental morbidity among migrants are common but not universal. differences in rates may reflect factors in: (a) the country of origin; (b) the actual move; (c) the country of settlement. about 1.8 million people came to britain in 1950-1970 from the west indies and indian subcontinent. they resembled gastarbeiters in other european countries, except that as commonwealth citizens they had the right of permanent residence. with their children (many of whom are now adults) they are 3.5 ... | 2011 | 3067527 |
| somatomedin c immunoreactivity in the achilles tendon varies in a dynamic manner with the mechanical load. | distribution of the trophic peptide somatomedin c (sm-c; insulin-like growth factor i; igf-i) immunoreactivity was mapped in normal achilles and tibialis anterior tendons. the spindle-shaped tendon fibroblasts showed faint perinuclear staining. fibroblasts in the paratenon mostly had a more intense igf-i immunoreactivity, i.e. faint to moderate. when analysing either tendon in detail, areas with more intense igf-i immunoreactivity could be recognized and seemed to correlate with areas of high me ... | 1988 | 3067520 |
| somatomedin c immunoreactivity in the achilles tendon varies in a dynamic manner with the mechanical load. | distribution of the trophic peptide somatomedin c (sm-c; insulin-like growth factor i; igf-i) immunoreactivity was mapped in normal achilles and tibialis anterior tendons. the spindle-shaped tendon fibroblasts showed faint perinuclear staining. fibroblasts in the paratenon mostly had a more intense igf-i immunoreactivity, i.e. faint to moderate. when analysing either tendon in detail, areas with more intense igf-i immunoreactivity could be recognized and seemed to correlate with areas of high me ... | 1988 | 3067520 |
| father's influence in the development of infant's relationships. | recent research on the father infant interaction has challenged the long held belief that the "most important thing a father can do for his children is to love their mother". fathers have significant influences on the development of the infant's relationships both directly and indirectly. certainly his greatest indirect influence is through supporting, protecting, and facilitating the maternal infant dyad when it is the primary nurturing relationship. new research from a variety of perspectives ... | 2010 | 3067507 |
| father's influence in the development of infant's relationships. | recent research on the father infant interaction has challenged the long held belief that the "most important thing a father can do for his children is to love their mother". fathers have significant influences on the development of the infant's relationships both directly and indirectly. certainly his greatest indirect influence is through supporting, protecting, and facilitating the maternal infant dyad when it is the primary nurturing relationship. new research from a variety of perspectives ... | 2010 | 3067507 |
| epidemiological patterns and incidence of bio-, sero- and phage types of vibrio cholerae in hyderabad, india, during 1971-1984. | during 1971-1984 out of 44,762 gastroenteritis cases bacteriologically examined, 4240 (9.5%) vibrio cholerae were isolated in hyderabad, india. out of them 1329 (31.3%) were classical and 2911 (68.7%) were el-tor biotypes. the changeover from classical to el-tor cholera was observed in hyderabad during 1975 and persisted. during this 14 year period four major outbreaks with v. cholerae serogroup o1 ogawa, v. cholerae biotype el-tor serogroup o1 ogawa were observed. phage types 1, 2 and 4 were pr ... | 1988 | 3067503 |
| alterations in the chemical composition and antigenicity of escherichia coli o89 lipopolysaccharide and lipid a after 60co gamma irradiation. | the chemical composition and the antigenicity of escherichia coli lipopolysaccharide (lps) and lipid a were investigated after irradiation with 150 kgy 60co-gamma ray. compared to the original preparations, the irradiated lps showed a significant reduction in glucosamine, glucose and galactose and a decrease in the phosphate content. the fatty acid components were reduced to a smaller degree. irradiation induced a reduction in the antigenicity of the polysaccharide part. the amount of glucosamin ... | 1988 | 3067502 |
| alterations in the chemical composition and antigenicity of escherichia coli o89 lipopolysaccharide and lipid a after 60co gamma irradiation. | the chemical composition and the antigenicity of escherichia coli lipopolysaccharide (lps) and lipid a were investigated after irradiation with 150 kgy 60co-gamma ray. compared to the original preparations, the irradiated lps showed a significant reduction in glucosamine, glucose and galactose and a decrease in the phosphate content. the fatty acid components were reduced to a smaller degree. irradiation induced a reduction in the antigenicity of the polysaccharide part. the amount of glucosamin ... | 1988 | 3067502 |
| [an abnormal origin of the ophthalmic artery arising from the middle meningeal artery]. | 2010 | 3067497 | |
| [an abnormal origin of the ophthalmic artery arising from the middle meningeal artery]. | 2010 | 3067497 | |
| is hysteroscopy of value in the investigation of female infertility? | a prospective multicentre study was designed to ascertain the value of hysteroscopy in the evaluation of female infertility. the study comprises 619 co2 hysteroscopies in women complaining of infertility. four hundred and ninety nine examinations (80%) were performed without anaesthesia or cervical dilatation. twenty eight cases of malformation were diagnosed. adhesions were found in 68 patients (11%), polypi in 56 (9.1%) and submucous fibroids in 51 (8.2%). endometrial hyperplasia was diagnosed ... | 2011 | 3067483 |
| [use of photosensitizing preparations in the treatment of cancer of the orl organs]. | 2011 | 3067440 | |
| [forensic medical service in the people's republic of bulgaria]. | 2011 | 3067425 | |
| [pharmacokinetics of non-steroidal anti-inflammatory agents in the elderly]. | 2011 | 3067421 | |
| [problems of ambulatory treatment of patients with a transplanted kidney]. | 2011 | 3067383 | |
| olsalazine in the treatment of active ulcerative colitis: a placebo controlled clinical trial and assessment of drug disposition. | the efficacy, safety and disposition of olsalazine was assessed in patients with left-sided ulcerative colitis or proctitis in a double-blind placebo controlled trial. thirty patients with a mild-to-moderate attack of ulcerative colitis were randomly allocated to olsalazine capsules, 1 g b.d., or placebo for 6 weeks. good clinical response was found in six patients receiving olsalazine and in two receiving placebo. improvement in sigmoidoscopic findings and histological appearance of rectal biop ... | 2011 | 3067339 |
| defective synthesis of apolipoprotein a-i in jejunal mucosa in coeliac disease. | apolipoprotein a-i was studied in biopsy specimens from the duodenojejunal junction by means of an indirect immunoperoxidase technique. in normal control subjects apolipoprotein a-i was immunohistochemically detected only in the absorptive cells at the tips of villi and was mainly localized supranuclearly. in 14 patients with coeliac disease apolipoprotein a-i was virtually undetectable. this implies that the inflammatory lesion in coeliac disease decreases the intestinal mass of apolipoprotein ... | 2011 | 3067329 |
| physiological adaptations to resistance exercise. implications for athletic conditioning. | resistance training results in a wide spectrum of adaptations in various physiological systems. increases in muscle size and strength, changes in body composition, neuroendocrine function and cardiovascular responses have been observed following resistance training. additionally, resistance training may be an effective means by which the incidence of sports injuries can be reduced. the physiological alterations induced by resistance training appear to be specific to the number of sets and repeti ... | 2011 | 3067312 |
| the expanding scope of pro review. explaining medicare's new review requirements in missouri. | 2010 | 3067067 | |
| the expanding scope of pro review. explaining medicare's new review requirements in missouri. | 2010 | 3067067 | |
| emphasis on preventive perinatology: a suitable alternative for developing countries. | the potential efficacy of preventive interventions in latin america to reduce perinatal morbidity and mortality is reviewed. the most important perinatal risk factors associated with pregnancy and delivery are young age of the mother, low socioeconomic status, low education, malnutrition, lack of prenatal care, pregnancy-induced-hypertension, perinatal infections, alcohol, smoking, and iatrogenic causes. adequate data are lacking to determine the magnitude of these factors in latin america. iatr ... | 2011 | 3065947 |
| [algodystrophies or post-traumatic dystrophies of reflex sympathetic origin]. | 2011 | 3065796 | |
| clinical pharmacokinetics of anthelmintic drugs. | a rational strategy for chemotherapy demands that dosage schedules be based on an adequate knowledge of clinical and biochemical pharmacology. many anthelmintic drugs (e.g. suramin, diethylcarbamazine, hycanthone) were introduced before modern techniques for drug evaluation (controlled clinical trials) and before the development of specific and sensitive analytical methods for the assay of drugs and metabolites in biological fluids. thus, many of the regimens used today for the treatment of para ... | 1988 | 3064952 |
| the use of the transcendental meditation programme in the prevention of drug abuse and in the treatment of drug-addicted persons. | the effectiveness of transcendental meditation (tm) in the prevention and reduction of drug abuse has been documented in many studies in the last 18 years. the programme is not a rehabilitation programme per se but is a means for self-development. thus, the resulting decrease in psychological problems and drug abuse is an automatic or secondary consequence of the practice of the meditation technique. since tm strengthens the individual and produces an overall and stable state of well-being, it n ... | 2011 | 3064844 |
| glucose inhibits prostacyclin production by cultured aortic endothelial cells. | a reduction in production of prostacyclin (pgi2) by the cells in the vascular wall may play a role in the pathogenesis of atherosclerosis in diabetic patients. the present study was undertaken to evaluate the effect of glucose on pgi2 production by endothelial cells in vitro. it was shown that pgi2 production by cultured bovine aortic endothelial cells was significantly reduced in the presence of a high concentration of glucose (300 mg/dl) compared with physiological concentrations of glucose (1 ... | 1988 | 3064357 |
| dental implants: physiologic and clinical comparisons of fibro-osteal and osteal integration. | 2010 | 3063602 | |
| dental implants: physiologic and clinical comparisons of fibro-osteal and osteal integration. | 2010 | 3063602 | |
| neurologic monitoring. | this article discusses the current methods for monitoring the intracranial environment in the critical care setting. intracranial pressure monitoring is discussed first. then the electroencephalogram and sensory evoked potentials are considered. finally, new techniques being evaluated are discussed. | 2011 | 3063351 |
| mode of action of morpholine derivatives. | 1988 | 3063169 | |
| noninvasive ultrasound investigation of cerebral vessels in the case of vertigo and dizziness. | 2011 | 3063093 | |
| proceedings of the jerusalem meeting of the society for research into hydrocephalus and spina bifida, 1988. | 2011 | 3062996 | |
| the appearance of transferrin receptors on cultured human cytotrophoblast and in vitro-formed syncytiotrophoblast. | using trypsinization and percoll gradient centrifugation, mononuclear cell populations were prepared from human term placentae. these populations consist mainly of cytotrophoblast, which probably lacks transferrin receptors. in vitro, transferrin receptors appear on these mononuclear cells and on syncytiotrophoblast formed in vitro, independently, of cellular fusion and proliferative state. | 1988 | 3062615 |
| [dysplastic nevus]. | 2008 | 3062614 | |
| [dysplastic nevus]. | 2008 | 3062614 | |
| associate degree nursing and the nursing home. | 2011 | 3062574 | |
| microbial keratitis complicating penetrating keratoplasty. | a retrospective review of 68 consecutive episodes of microbial keratitis complicating 66 penetrating keratoplasties (pks) showed major risk associations: suture-related problems (50%), contact lens wear (26%), previous herpes simplex infection (15%), graft failure (15%), and persistent epithelial defects (15%). topical steroid (85%) and antibiotic (59%) usage were common iatrogenic factors. half the infections occurred more than 1 year after grafting. bacterial infections involving gram-positive ... | 2008 | 3062538 |
| antipeptide monoclonal antibodies inhibit the binding of rabies virus glycoprotein and alpha-bungarotoxin to the nicotinic acetylcholine receptor. | it has been reported that binding to muscle nicotinic acetylcholine receptor at the post-synaptic membrane is an important event of the rabies virus neurotropism. the binding site can be located within the 190-203 region of the virus glycoprotein sharing a high degree of homology with the "toxic loop" of the curare-mimetic snake neurotoxins. we have synthesized a tetradecapeptide corresponding to this glycoprotein region and used it, following conjugation with an immunogenic carrier to raise mab ... | 1988 | 3062388 |
| [two cases of retroperitoneal lymphangioma]. | 2011 | 3062209 | |
| isolation and chemical analysis of 7-o-(2-amino-2-deoxy-alpha-d-glucopyranosyl)-l-glycero-d-manno-heptose as a constituent of the lipopolysaccharides of the udp-galactose epimerase-less mutant j-5 of escherichia coli and vibrio cholerae. | methyl 7-o-(2-amino-2-deoxy-alpha-d-glucopyranosyl)-l-glycero-d-manno-hepto+ ++ pyranoside (1) was released from the lipopolysaccharide of the udp-galactose epimerase-less mutant j-5 of escherichia coli by methanolysis and isolated by high-voltage paper electrophoresis. its chemical structure was determined by chemical analysis, deamination with nitrous acid, g.1.c.-m.s., and 1h- and 13c-n.m.r. spectroscopy performed on its acetylated derivative. the disaccharide moiety of 1 was also detected in ... | 1988 | 3061645 |
| [characteristics of the protease activity of vibrio cholerae strains and mutants with various biological properties]. | the study of 65 v. cholerae strains and mutants revealed that protease activity was high in choleragenic strains and mostly low, sometimes even not manifested, in noncholeragenic strains. the use of inhibitors made it possible to determine three types of protease. choleragenic strains were found to possess all three types of protease, while in noncholeragenic strains only protease of type 1 was detected in very rare cases. in noncholeragenic hemolytic strains and mutants protease of type 3 and i ... | 1988 | 3061263 |
| [pathogenicity factors of vibrio cholerae]. | 1988 | 3061255 | |
| [statistical study of hydatid locations. apropos of 644 cases--1980-1988]. | 2010 | 3061096 | |
| [statistical study of hydatid locations. apropos of 644 cases--1980-1988]. | 2010 | 3061096 | |
| [echographic and radiographic aspects of a case of burkitt's lymphoma]. | 2011 | 3060909 | |
| [management of patients with dilated cardiomyopathy]. | 2010 | 3060659 | |
| [management of patients with dilated cardiomyopathy]. | 2010 | 3060659 | |
| fungal infections in aids. cryptococcosis. | cryptococcus neoformans, histoplasma capsulatum, and coccidioides immitis are the three fungi that regularly cause disseminated, life-threatening disease in patients with aids. cryptococcosis is the fourth most common opportunistic infection in patients with aids and results in meningitis or pneumonia or both, in most cases. in addition, there have been unusual focal infections described and even unexplained fever alone. in any patient at risk for hiv infection, routine screening tests should in ... | 1988 | 3060529 |
| occupational health issues for providers of care to patients with hiv infection. | the perception that hiv is a highly contagious nosocomial pathogen persists despite a great deal of evidence to the contrary. however, health care workers are at a low but finite risk of occupational infection with the virus, particularly through accidental needle-stick inoculations with infected blood. universal blood and body fluid precautions minimize the risk of nosocomial transmission of a variety of pathogens, including hiv, and should be routinely employed by all health care workers for a ... | 1988 | 3060519 |
| effect of dexamethasone on experimental escherichia coli mastitis in the cow. | the effect of intramuscular administration of dexamethasone on milk production and on several clinical and hematologic indicators in cows with experimental escherichia coli mastitis was studied. two groups of three cows each were intramammarily inoculated with 20 x 10(5) cfu e. coli 0101 k99 f41 in rear quarters. immediately after inoculation one groups received 30 mg dexamethasone intramuscularly, whereas the other group was injected similarly with pyrogen-free saline. fourteen days later milk ... | 1988 | 3060491 |
| identification and localization of a novel, cytoskeletal, centrosome-associated protein in ptk2 cells. | antisera raised against centrin (salisbury, j.l., a.t. baron, b. surek, and m. melkonian. 1984. j. cell biol. 99:962-970) have been used, here, to identify a centrosome-associated protein with an mr of 165,000. immunocytochemistry indicates that this protein is a component of pericentriolar satellites, basal feet, and pericentriolar matrix of interphase cells. these components of pericentriolar material are, in part, composed of 3-8-nm-diam filaments, which interconnect to form a three-dimension ... | 1988 | 3060471 |
| influence of pontic material on alveolar mucosal conditions. | the purpose of the present study was to investigate plaque accumulation and inflammatory changes in the mucosa beneath fixed bridge pontics of various materials, in patients cleaning the infrapontic space daily. fixed bridges with a tight but non-compressive contact to the mucosa in the pontic area and with interchangeable test specimens placed in the pontic base were constructed for five patients. during 4-wk periods the following materials were tested: alloys with a high or a low gold content, ... | 2010 | 3059449 |
| [leonardo da vinci and his physician-contemporaries]. | 2011 | 3059261 | |
| morbidity and mortality of carotid endarterectomy under local anesthesia: a retrospective study. | it has been shown that carotid endarterectomy reduces the incidence of stroke in patients with symptomatic extracranial occlusive vascular disease in the absence of major perioperative complications such as stroke or death. we present a retrospective study of 106 carotid endarterectomies performed under local anesthesia in 100 patients in whom transient ischemic attack (tia) or minor stroke had occurred. nonfatal stroke occurred in 2%, and tia occurred in 1%. there was no perioperative mortality ... | 2011 | 3059211 |
| rish. vii: cell surface patterns--association of like cells. | like-cells associate to form various tissues, and it has been demonstrated that this specificity resides in the plasma membrane. membrane bound tissue specific antigens and enzyme substrate mechanisms have been considered to be involved in this phenomena, but these explanations are incomplete. it is proposed that like-cells identify each other by specific complementary cell-surface patterns. this complementarity results from cell division. that is, when cells divide, they give rise to a mirror i ... | 2010 | 3059143 |
| an epidemic of multiresistant salmonella typhimurium with a characteristic plasmid profile among calves in tokachi district, japan. | 1988 | 3058996 | |
| a precision alignment frame for endosseous post dental implants. | the advantages of the precision alignment frame are that it (1) accurately positions and aligns the initial pilot drill at implant surgery, (2) has no adverse effects on the diagnostic cast, (3) eliminates the need for an incision or raising a flap when locating a submerged implant root for transmucosal connection, (4) consistently and accurately records the relation of the implant root to the radiograph, (5) permits long-term evaluation of the implant after restoration, (6) has components that ... | 2010 | 3058942 |
| a precision alignment frame for endosseous post dental implants. | the advantages of the precision alignment frame are that it (1) accurately positions and aligns the initial pilot drill at implant surgery, (2) has no adverse effects on the diagnostic cast, (3) eliminates the need for an incision or raising a flap when locating a submerged implant root for transmucosal connection, (4) consistently and accurately records the relation of the implant root to the radiograph, (5) permits long-term evaluation of the implant after restoration, (6) has components that ... | 2010 | 3058942 |
| nonionic contrast agents and coagulation. | the chemotoxicity of nonionic and ionic contrast media is discussed with reference to chemical structure. second-generation nonionic contrast media have the lowest chemotoxicity of any agents because of the uniform distribution of hydrophilic groups around the molecule, which mask the hydrophobic iodine atoms. previous investigations show that second-generation nonionic agents have the same qualitative hematologic effects as other contrast agents. the less marked quantitative hematologic effects ... | 2010 | 3058638 |
| general anesthetics. | 2010 | 3058610 | |
| genetic fusion of a non-toxic heat-stable enterotoxin-related decapeptide antigen to cholera toxin b-subunit. | a decapeptide highly homologous to the sta escherichia coli heat-stable enterotoxin and to several other heat-stable enterotoxins was fused genetically to the amino-end of the b-subunit of cholera toxin (ctb) and the hybrid protein gene expressed from a tacp overexpression system. the sta-related decapeptide used, which was encoded by a synthetic oligodeoxynucleotide, contained a single mutation which substituted a disulfide-linked cysteine by alanine. after its fusion to ctb the decapeptide was ... | 1988 | 3058509 |
| factors affecting the survival of pathogenic bacteria in subtropical river water. | the present study was carried out to determine the factors causing the disappearance of introduced salmonella enteritidis, staphylococcus aureus, and vibrio cholerae in natural river water. when large numbers of the above organisms (final level 10(7)-10(8) cfu per ml) were added to river water, the decline of their numbers coincided with increasing numbers of protozoa. furthermore, their survival was improved dramatically if the river water was amended with a eucaryote inhibitor. after comparing ... | 1988 | 3058406 |
| current perspectives on the epidemiology and pathogenesis of clinically significant vibrio spp. | recent taxonomic advances have now implicated several different vibrio species as human pathogens. while the most common clinical presentation of vibrio infection continues to be gastroenteritis, an increasing number of extraintestinal infections are being reported, particularly in immunocompromised individuals. detection of vibrio infections requires a good clinical history and the use of appropriate isolation and identification procedures by the laboratory to confirm illnesses attributed to vi ... | 1988 | 3058295 |
| a mutant human proinsulin is secreted from islets of langerhans in increased amounts via an unregulated pathway. | a coding mutation in the human insulin gene (his-b10----asp) is associated with familial hyperproinsulinemia. to model this syndrome, we have produced transgenic mice that express high levels of the mutant prohormone in their islets of langerhans. strain 24-6 mice, containing about 100 copies of the mutant gene, were normoglycemic but had marked increases of serum human proinsulin immunoreactive components. biosynthetic studies on isolated islets revealed that approximately 65% of the proinsulin ... | 1988 | 3057496 |
| a mutant human proinsulin is secreted from islets of langerhans in increased amounts via an unregulated pathway. | a coding mutation in the human insulin gene (his-b10----asp) is associated with familial hyperproinsulinemia. to model this syndrome, we have produced transgenic mice that express high levels of the mutant prohormone in their islets of langerhans. strain 24-6 mice, containing about 100 copies of the mutant gene, were normoglycemic but had marked increases of serum human proinsulin immunoreactive components. biosynthetic studies on isolated islets revealed that approximately 65% of the proinsulin ... | 1988 | 3057496 |
| criteria for an increased specificity of mri interpretation in elderly subjects with suspected multiple sclerosis. | we reviewed the mris of 49 asymptomatic volunteers (age range, 31 to 77 years) and of 50 ms patients (age range, 14 to 63) for areas of increased signal (ais) and features discriminating ms lesions from lesions seen with normal aging. we obtained optimal specificity of mri interpretation (100%) if we required at least two of the following three ais features--size greater than or equal to 6 mm, abutting ventricular bodies, infratentorial location--for a positive mri diagnosis of ms. applying thes ... | 2011 | 3057397 |
| [molecular basis of human hereditary diseases caused by gene expression deficiency]. | the recent literature on the structure of mutant human genes determining the phenotypic expression of hereditary diseases is reviewed. the main types of gene mutations are described including deletions and insertions, mutations impairing translation and posttranslational protein processing, m-rna processing, causing transcription blocks, ultimate or partial quantitative deficiency in proteins-gene products. the problems of genetic heterogeneity of hereditary diseases and diagnosis of the latter ... | 1988 | 3057356 |
| [molecular basis of human hereditary diseases caused by gene expression deficiency]. | the recent literature on the structure of mutant human genes determining the phenotypic expression of hereditary diseases is reviewed. the main types of gene mutations are described including deletions and insertions, mutations impairing translation and posttranslational protein processing, m-rna processing, causing transcription blocks, ultimate or partial quantitative deficiency in proteins-gene products. the problems of genetic heterogeneity of hereditary diseases and diagnosis of the latter ... | 1988 | 3057356 |
| fabric of many-colored threads. | 2010 | 3056893 | |
| fabric of many-colored threads. | 2010 | 3056893 | |
| use of thymic grafts or thymic factors to augment immunologic recovery after bone marrow transplantation: brief report with 2 to 12 years' follow-up. | thymus tissue implants, thymic epithelial cells obtained from third party donors sharing one hla-a and -b locus with the recipient, or the thymic hormones thymosin fraction 5 and thymopentin were given to recipients of hla-identical sibling bone marrow to prevent chronic graft-versus-host disease (gvhd) and accelerate immunologic reconstitution. the clinical courses of 17 patients receiving thymus tissue and 18 patients receiving thymic hormones were reported initially 5 years ago and showed no ... | 2011 | 3056551 |
| in vivo localization and biological effect of anti-yolk sac monoclonal antibodies. | two monoclonal antibodies directed against rat yolk sac antigen 1 (mab 6d1) and yolk sac antigen 2 (mab 3c3) were injected i.v. into pregnant or tumor-bearing rats. immunofluorescent examination of the different organs from animals killed, 2, 24, or 48 hours after inoculation showed the specific binding of mab 6d1 to the free surface of visceral endoderm cells in pregnant animals and on visceral cells of yolk sac carcinoma. the mab 3c3 reacted only with the endoderm of parietal yolk sac and with ... | 1988 | 3056111 |
| [the vesalius of human embryology]. | human embryology was founded 100 years ago by wilhelm his, who may rightly be called the "vesalius of human embryology". 3 landmarks were published in germany within a quarter of a century: the anatomie menschlicher embryonen of his, keibel's normentafeln, and keibel and mall's handbuch der entwicklungsgeschichte des menschen. the staging of the human embryo, now associated with the names of streeter and o'rahilly, was first proposed by mall in anatomischer anzeiger. | 1988 | 3056108 |
| a comparative study of cardiac output measurement by dye dilution and pulsed doppler ultrasound. | dye dilution was compared with pulsed doppler for the measurement of cardiac output in eighteen children being ventilated after cardiac surgery. the mean difference between the two techniques was -0.04/min (dye minus doppler) with 95% confidence limits of 0.25 l/min and -0.33 l/min over a cardiac output range 0.27-6.12 l/min; this difference is not significant. calculation of the product-moment correlation coefficient showed a close relationship between the dye dilution and doppler methods with ... | 2010 | 3056088 |
| [morphologic characterization of the pathogenic action of cholera and nonagglutinating vibrios]. | 1988 | 3055769 | |
| non-o:1 vibrio cholerae bacteremia: case report and review. | a case of non-o:1 vibrio cholerae bacteremia and prostatic abscess in a patient with idiopathic aplastic anemia was studied, and the data were compared with those from 23 previously reported cases of non-o:1 v. cholerae bacteremia. the case-fatality rate for the 13 cases for which the outcome is known is 61.5%. the majority of known cases have occurred in immunocompromised patients, particularly those with hematologic malignancy or cirrhosis. host susceptibility is potentially important in this ... | 1988 | 3055182 |
| [reversible suppression and activation of immunoglobulin genes in differentiated igg+ sublines of human rpmi-6410t b-cells]. | differentiated human b-cells of the igg+ sublines obtained as a result of switching from igm to igg synthesis in the 6410t line and its igm+ lines gradually reduce the level of igm secretion after the inductor removal. igg synthesis can be partially or fully recovered by treating the igg+ sublines with a polyclonal activator of b-lymphocytes, lipopolysaccharide w from gram negative bacteria. in the conditions of certain regulatory effects, differentiated igg+ cells are capable to pass reversibly ... | 1988 | 3054675 |
| accumulation of lamb-lacz hybrid proteins in intracytoplasmic membrane-like structures in escherichia coli k12. | the subcellular location of lamb-lacz hybrid proteins in the escherichia coli k12 strains pop3234 and pop3299 was investigated by immunocytochemical detection and protease-accessibility experiments. induction of the synthesis of the hybrid proteins resulted in the appearance of membrane-like structures within the cytoplasm of the cells. labelling of ultrathin cryosections of the cells with anti-beta-galactosidase or anti-lamb protein serum and protein-a-gold complexes revealed that the hybrid pr ... | 1988 | 3053974 |
| motility of campylobacter jejuni in a viscous environment: comparison with conventional rod-shaped bacteria. | the motility of four strains of campylobacter jejuni in solutions of varying viscosity was measured and compared to that of a number of conventional rod-shaped bacteria (crsb). all the bacteria tested showed an initial increase in velocity in the low viscosity solutions--between 1 and 3 centipoise (1 p = 0.1 pa s). however, only the campylobacters were actively motile in highly viscous solutions with velocities ranging from 60 to 100 micron s-1. all strains of c. jejuni tested showed three separ ... | 1988 | 3053972 |
| detection of vibrio cholerae with monoclonal antibodies specific for serovar o1 lipopolysaccharide. | six hybridoma cell lines, each of which produced a monoclonal antibody (mab) against vibrio cholerae o1 lipopolysaccharide (lps), were established. each mab was active serologically by both enzyme-linked immunosorbent assay (elisa) and the slide agglutination test. in the elisa, each mab was tested against 7 o1 and 9 non-o1 lps preparations. three mabs reacted with both inaba and ogawa serovars (a antigen), two mabs reacted with the ogawa serovars only (b antigen), and one mab reacted with the i ... | 1988 | 3053778 |
| spiramycin does not increase plasma cyclosporin concentrations in renal transplant patients. | 2011 | 3053210 | |
| [2 hemocultures positive for vibrio cholerae]. | the authors report two cases of vibrio cholerae isolation in hemocultures even though the copro-cultures where negative. in both cases, post-operated patients are concerned. the first one had supported a renal transplantation and was under immuno-depressor. the second one, after an aorto-aneurysm surgical treatment suffered from a mesenteric infarct. during the disease the vibrio was found in the hemoculture. | 1988 | 3052896 |
| [bacteriologic characteristics of 25 strains of vibrio cholerae, biotype eltor isolated in mali]. | this work studies bacteriological characters of 25 strains of v. cholerae isolated in mali during the outbreak of 1984-1987. these strains were precisely identified by biochemistry characters, toxin secretion, presence of a structure considered as attachment factor. antibiotic susceptibility study confirmed the great sensibility of v. cholerae to this products, and allowed to classify them according to their cl90. this contribution of the laboratory is very interesting for the control of the dis ... | 1988 | 3052895 |
| successful pterygium surgery. | 2011 | 3052530 | |
| comparison between lysine vasopressin and a long-acting analogue (n alpha-triglycyl-lysine vasopressin) used as local hemostatic agents for conization. | lysine vasopressin and a long-acting analogue n alpha-triglycyl-lysine vasopressin were compared in a prospective randomized double-blind study including 71 women undergoing cold knife conization of the uterine cervix. hemodynamic and hemostatic variables were studied. n alpha-triglycyl-lysine vasopressin had the following advantages over lysine vasopressin: it gave significantly less skin pallor, becoming evident at a later stage during the operation. the diastolic blood pressure was significan ... | 2011 | 3051878 |
| [instability of immunoglobulin expression during differentiation induction in the human lymphoblastoid cell line rpmi-6410t]. | the induction of immunoglobulin heavy chain classes switch from igm to igg was demonstrated in vitro in cells of rpmi-6410t line. the igg+-sublines, formed as a result of the switch are characterized by instability of igg synthesis. after removal of the inductor from the growth environment, igg+ cells gradually reduce the level of secreted igg. such a transition to the functional rest state is likely to be connected with the convertible ig-gene activity suppression in igg+ cells, since after the ... | 1988 | 3051603 |
| [pro-allergy role of infection. a component of the mode of reacting]. | no organism from the cradle lives germ-free or allergen-free. the modalities by which infections facilitate conditions of abnormal reactivity, in particular respiratory asthma and allergy to cow milk proteins, are examined. 216 asthmatic children and 50 infants with rotavirus enteritis have been considered. infections, besides representing stimuli directly projected on the immune system, also constitute factors which more generally influence the way of reacting. | 1988 | 3050902 |
| office evaluation and management of the shoulder impingement syndrome. | the shoulder impingement syndrome is the most common cause of shoulder pain. a complete office evaluation can be aided by a printed exam sheet. careful consideration of the differential diagnosis is important, often employing the xylocaine injection test. the impingement syndrome responds to conservative treatment the majority of the time. long follow-up determines the need for an invasive evaluation or surgical treatment. | 2011 | 3050719 |
| botulinum toxin a-induced protective ptosis in corneal disease. | botulinum toxin a produces a temporary, flaccid ptosis when injected into the levator palpebrae superioris muscle. the resulting protective ptosis was used to aid healing in 21 cases of indolent ulceration, and, prophylactically, in 4 cases of neuroparalytic keratitis. of the indolent ulcers, 90% healed completely. in all but one case, the cornea was covered completely by the lid and complete ptosis was produced in 75% of cases in an average of 3.6 days, lasting for 16 days on average before rec ... | 2011 | 3050691 |
| production and partial purification of a fluid-accumulating factor of non-o1 vibrio cholerae. | a fluid-accumulating factor (faf in the ligated rabbit ileal loop test) from a strain of non-o1 vibrio cholerae not producing cholera toxin-like enterotoxin (ctlt) was partially purified by ammonium sulfate precipitation, gel filtration with sephadex g-100, and deae cellulose column chromatography. the preparation thus obtained showed collagenolytic, cytolytic, necrotic, and hemorrhagic activities, but was not lethal to mice nor hemolytic to sheep erythrocytes. desquamation of epithelial cells, ... | 1988 | 3050379 |
| extracellular proteins of vibrio cholerae: nucleotide sequence of the structural gene (hlya) for the haemolysin of the haemolytic el tor strain 017 and characterization of the hlya mutation in the non-haemolytic classical strain 569b. | the ei t or haemolysin, product of hlya, is exported from vibrio cholerae as a mr 80,000 protein which can be subsequently cleaved to give two proteins of mr 65,000 and 15,000. nucleotide sequence analysis has demonstrated that hlya encodes a protein of mr 82,250 with a potential 18-amino-acid signal sequence. the non-haemolytic classical strain 569b has been shown to have a structural gene defect rather than a defect in secretion. by non-reciprocal recombination it was possible to transfer this ... | 1988 | 3050359 |
| immunoglobulin a deposition in jejunal mucosa of children with dermatitis herpetiformis. | previously we have shown by indirect immunofluorescence (if) technique that a special iga antibody in the sera of patients with dermatitis herpetiformis (dh) binds to the structures of the normal jejunum. now we show by direct if that specific iga deposits are present in the proximal jejunum of 11/12 dh and 2/2 celiac patients before a gluten-free diet (gfd). the iga deposition was in a tubular pattern underlying the villous and crypt epithelial basement membranes and in the lamina propria. this ... | 2010 | 3049830 |
| immunoglobulin a deposition in jejunal mucosa of children with dermatitis herpetiformis. | previously we have shown by indirect immunofluorescence (if) technique that a special iga antibody in the sera of patients with dermatitis herpetiformis (dh) binds to the structures of the normal jejunum. now we show by direct if that specific iga deposits are present in the proximal jejunum of 11/12 dh and 2/2 celiac patients before a gluten-free diet (gfd). the iga deposition was in a tubular pattern underlying the villous and crypt epithelial basement membranes and in the lamina propria. this ... | 2010 | 3049830 |