Publications

quantitative distribution of salmonella spp. and escherichia coli on beef carcasses and raw beef at retail establishments.	salmonella is a foodborne pathogen that commonly inhabits the gastrointestinal tract of a healthy feedlot cattle and can be transferred to the carcass surface during hide removal and evisceration procedures. numerous investigations on salmonella prevalence throughout different stages of the beef chain have been conducted. in contrast, limited studies are available on quantitative determinations of salmonella at different steps in raw meat production. quantitative data, particularly for pathogeni ...	2015	26125489
a boundary value approach to optimization with an application to salmonella competition.	we develop a novel optimization framework to study strategies in ecological competition processes. the optimization method uses theory from dynamical systems describing the asymptotic behavior of a bistable system based on initial conditions, which we implement using a numerical boundary value problem. as an application of our method, we develop a model of the competition between salmonella typhimurium and the host's native microflora, which constantly and densely inhabit the intestinal lining o ...	2015	26122824
antimicrobial activity of customary medicinal plants of the yaegl aboriginal community of northern new south wales, australia: a preliminary study.	this study is a collaboration between macquarie university researchers and the yaegl aboriginal community of northern nsw, australia to investigate the antimicrobial potential of plants used in the topical treatment of wounds, sores and skin infections. based on previously documented medicinal applications, aqueous and aqueous ethanolic extracts of alocasia brisbanensis, canavalia rosea, corymbia intermedia, hibbertia scandens, ipomoea brasiliensis, lophostemon suaveolens and syncarpia glomulife ...	2015	26122212
quantification of viable but nonculturable salmonella spp. and shigella spp. during sludge anaerobic digestion and their reactivation during cake storage.	the presence of viable but nonculturable (vbnc) bacterial pathogens which often fail to be detected by cultivation and can regain the cultivability if the living conditions improve were reported. the objective of this study was to determine the occurrence of vbnc salmonella spp. and shigella spp. in the biosolids during anaerobic digestion and its reactivation during the cake storage.	2015	26119588
salmonella typhimurium outbreak associated with a contaminated food container in a school in sichuan province, china.	on 13 june 2013, a fever and diarrhoea outbreak occurred in a boarding school in sichuan province. we conducted a field investigation and compared food exposure of 81 case students and 104 control students (years 7 and 8) in order to identify the source of infection. there were 401 cases identified (399 students and two cooks). the attack rates were 23-46% in nursery, primary, and secondary schools, but 0% in the high school. eighty-five percent of case students, consumed cowpea salad compared t ...	2016	26119077
generating a metal-responsive transcriptional regulator to test what confers metal sensing in cells.	frmr from salmonella enterica serovar typhimurium (a csor/rcnr-like transcriptional de-repressor) is shown to repress the frmra operator-promoter, and repression is alleviated by formaldehyde but not manganese, iron, cobalt, nickel, copper, or zn(ii) within cells. in contrast, repression by a mutant frmre64h (which gains an rcnr metal ligand) is alleviated by cobalt and zn(ii). unexpectedly, frmr was found to already bind co(ii), zn(ii), and cu(i), and moreover metals, as well as formaldehyde, t ...	2015	26109070
a mannose family phosphotransferase system permease and associated enzymes are required for utilization of fructoselysine and glucoselysine in salmonella enterica serovar typhimurium.	salmonella enteric serovar typhimurium, a major cause of food-borne illness, is capable of using a variety of carbon and nitrogen sources. fructoselysine and glucoselysine are maillard reaction products formed by the reaction of glucose or fructose, respectively, with the ε-amine group of lysine. we report here that s. typhimurium utilizes fructoselysine and glucoselysine as carbon and nitrogen sources via a mannose family phosphotransferase (pts) encoded by gfrabcd (glucoselysine/fructoselysine ...	2015	26100043
salmonella engages host micrornas to modulate sumoylation: a new arsenal for intracellular survival.	posttranslational modifications (ptms) can alter many fundamental properties of a protein. one or combinations of them have been known to regulate the dynamics of many cellular pathways and consequently regulate all vital processes. understandably, pathogens have evolved sophisticated strategies to subvert these mechanisms to achieve instantaneous control over host functions. here, we present the first report of modulation by intestinal pathogen salmonella enterica serovar typhimurium (s. typhim ...	2015	26100020
the periplasmic nitrate reductase napabc supports luminal growth of salmonella enterica serovar typhimurium during colitis.	the food-borne pathogen salmonella enterica serovar typhimurium benefits from acute inflammation in part by using host-derived nitrate to respire anaerobically and compete successfully with the commensal microbes during growth in the intestinal lumen. the s. typhimurium genome contains three nitrate reductases, encoded by the narghi, narzyv, and napabc genes. work on homologous genes present in escherichia coli suggests that nitrate reductase a, encoded by the narghi genes, is the main enzyme pr ...	2015	26099579
inactivation of pathogenic bacteria inoculated onto a bacto™ agar model surface using tio2-uvc photocatalysis, uvc and chlorine treatments.	the aim of this study was to study inactivation of different pathogenic bacteria on agar model surface using tio2-uv photocatalysis (tuvp).	2015	26099167
salmonella typhimurium and escherichia coli dissimilarity: closely related bacteria with distinct metabolic profiles.	live attenuated strains of salmonella typhimurium have been extensively investigated as vaccines for a number of infectious diseases. however, there is still little information available concerning aspects of their metabolism. s. typhimurium and escherichia coli show a high degree of similarity in terms of their genome contents and metabolic networks. however, this work presents experimental evidence showing that significant differences exist in their abilities to direct carbon fluxes to biomass ...	2015	26097206
cold plasma inactivation of internalised bacteria and biofilms for salmonella enterica serovar typhimurium, listeria monocytogenes and escherichia coli.	microbial biofilms and bacteria internalised in produce tissue may reduce the effectiveness of decontamination methods. in this study, the inactivation efficacy of in-package atmospheric cold plasma (acp) afterglow was investigated against salmonella typhimurium, listeria monocytogenes and escherichia coli in the forms of planktonic cultures, biofilms formed on lettuce and associated bacteria internalised in lettuce tissue. prepared lettuce broth (3%) was inoculated with bacteria resulting in a ...	2015	26093991
characterization of the invasive, multidrug resistant non-typhoidal salmonella strain d23580 in a murine model of infection.	a distinct pathovar of salmonella enterica serovar typhimurium, st313, has emerged in sub-saharan africa as a major cause of fatal bacteremia in young children and hiv-infected adults. d23580, a multidrug resistant clinical isolate of st313, was previously shown to have undergone genome reduction in a manner that resembles that of the more human-restricted pathogen, salmonella enterica serovar typhi. it has since been shown through tissue distribution studies that d23580 is able to establish an ...	2015	26091096
complete genome sequencing of a multidrug-resistant and human-invasive salmonella enterica serovar typhimurium strain of the emerging sequence type 213 genotype.	salmonella enterica subsp. enterica serovar typhimurium strain yu39 was isolated in 2005 in the state of yucatán, mexico, from a human systemic infection. the yu39 strain is representative of the multidrug-resistant emergent sequence type 213 (st213) genotype. the yu39 complete genome is composed of a chromosome and seven plasmids.	2015	26089426
fatty acids composition and biofilm production of attenuated salmonella typhimurium dam and seqa mutants after exposure to uv-c.	the goal of this work was the investigation of correlation between some peculiarities of membrane fatty acids composition, biofilm formation, and motility of dam and/or seqa mutants in salmonella typhimurium bacterial cells and uv-c radiations. the exposure changed the fatty acids composition of dam and seqa/dam strains. significant increase of unsaturated fatty acids was observed. swarming and swimming were enhanced only in dam mutant and biofilm formation increased significantly in all tested ...	2015	26088950
pichia pastoris x-33 has probiotic properties with remarkable antibacterial activity against salmonella typhimurium.	probiotics are live microorganisms which are beneficial for the host when ingested at high enough concentrations. the methylotrophic yeast pichia pastoris is widely used as heterologous protein production platform. however, its use as probiotic is poorly studied. the objective of this study was to evaluate some probiotic properties of the p. pastoris strain x-33 wild type. the resistance to in vitro and in vivo gastrointestinal conditions, stability in feed, safety, and antibacterial activity ag ...	2015	26088173
the anti-infective activity of punicalagin against salmonella enterica subsp. enterica serovar typhimurium in mice.	punicalagin, a major bioactive component of pomegranate peel, has been proven to have antioxidant, antiviral, anti-apoptosis, and hepatoprotective properties. the aim of this study was to investigate the anti-infective activity of punicalagin in a mouse model. c57bl/6 mice were initially challenged with salmonella enterica subsp. enterica serovar typhimurium (s. typhimurium) and then treated with punicalagin. food and water consumption and body weight were recorded daily. on day 8 post infection ...	2015	26084785
crystal structure of dsba from corynebacterium diphtheriae and its functional implications for cuep in gram-positive bacteria.	in gram-negative bacteria in the periplasmic space, the dimeric thioredoxin-fold protein dsbc isomerizes and reduces incorrect disulfide bonds of unfolded proteins, while the monomeric thioredoxin-fold protein dsba introduces disulfide bonds in folding proteins. in the gram-negative bacteria salmonella enterica serovar typhimurium, the reduced form of cuep scavenges the production of hydroxyl radicals in the copper-mediated fenton reaction, and dsbc is responsible for keeping cuep in the reduced ...	2015	26082031
fluoroquinolone induction of phage-mediated gene transfer in multidrug-resistant salmonella.	fluoroquinolones are broad-spectrum antibiotics that inhibit bacterial dna gyrase and topoisomerase activity, which can cause dna damage and result in bacterial cell death. in response to dna damage, bacteria induce an sos response to stimulate dna repair. however, the sos response may also induce prophage with production of infectious virions. salmonella strains typically contain multiple prophages, and certain strains including phage types dt120 and dt104 contain prophage that upon induction a ...	2015	26078016
correction: signatures of adaptation in human invasive salmonella typhimurium st313 populations from sub-saharan africa.		2015	26076129
melissa officinalis l. decoctions as functional beverages: a bioactive approach and chemical characterization.	lemon balm (melissa officinalis l.) is a member of the lamiaceae family with a long story of human consumption. it has been consumed for decades, directly in food and as a decoction or an infusion for its medicinal purposes. in this manuscript, a detailed chemical characterization of the decoction of this plant is described, encompassing antimicrobial, antioxidant and antitumor activities. rosmarinic acid and lithospermic acid a were the most abundant phenolic compounds. quinic acid, fructose, g ...	2015	26075899
characterization of salmonella enterica serovar typhimurium and salmonella enterica serovar 4,[5],12:i:- isolates from pigs presenting with diarrhea in korea.	between 2011 and 2012, a total of 896 pig fecal samples were collected from nine provinces in korea, and 50 salmonella enterica susp. enterica serovar typhimurium (s. typhimurium) was isolated. the characteristics of the 50 strains were analyzed, and 4 strains were identified as salmonella enterica subsp. enterica serovar 4,[5],12:i:-. salmonella 4,[5],12:i:- could not be distinguished from s. typhimurium through phage typing, antimicrobial resistance testing or multiple-locus variable-number ta ...	2015	26074410
toxicogenetic effects of low concentrations of the pesticides imidacloprid and sulfentrazone individually and in combination in in vitro tests with hepg2 cells and salmonella typhimurium.	the insecticide imidacloprid and the herbicide sulfentrazone are two different classes of pesticides that are used for pest control in sugarcane agriculture. to evaluate the genotoxic potential of low concentrations of these two pesticides alone and in mixture, the comet assay and the micronucleus (mn) test employing fluorescence in situ hybridization (fish) with a centromeric probe were applied in human hepatoma cell lines (hepg2), in a 24-h assay. mutagenicity was assessed by salmonella/micros ...	2015	26074310
synergistic antibacterial effect of silver nanoparticles combined with ineffective antibiotics on drug resistant salmonella typhimurium dt104.	synergistic antibacterial activity of combined silver nanoparticles (agnps) with tetracycline (polykeptide), neomycin (aminoglycoside), and penicillin (β-lactam) was tested against the multidrug resistant bacterium salmonella typhimurium dt104. dose-dependent inhibition of salmonella typhimurium dt104 growth is observed for tetracycline-agnps and neomycin-agnps combination with ic50 of 0.07 μg/ml and 0.43 μg/ml, respectively. there is no inhibition by the penicillin-agnps combination. these resu ...	2015	26072671
back to the future: are tumor-targeting bacteria the next-generation cancer therapy?	cancer patients infected with various bacteria were reported, for at least two centuries, to have spontaneous remission. w.b. coley, of what is now the memorial sloan-kettering cancer center, pioneered bacterial therapy of cancer in the clinic with considerable success beginning in the late nineteenth century. after coley died in 1936, bacterial therapy of cancer essentially ended. currently there is much excitement in developing bacterial therapy for treating cancer using either obligate or fac ...	2015	26072411
an enterobacterial common antigen mutant of salmonella enterica serovar typhimurium as a vaccine candidate.	due to increasing rates of invasive salmonella enterica serovar typhimurium infection, there is a need for an effective vaccine to prevent this disease. previous studies showed that a mutation in the first gene of the enterobacterial common antigen biosynthetic pathway, weca, resulted in attenuation of s. typhimurium in a murine model of salmonellosis. furthermore, immunization with a weca(-) strain protected against lethal challenge with the parental wild type s. typhimurium strain. herein, we ...	2015	26070977
acetylation regulates survival of salmonella enterica serovar typhimurium under acid stress.	the ability to acetylate lysine residues is conserved across organisms, and acetylation of lysine residues plays important roles in various cellular functions. maintaining intracellular ph homeostasis is crucial for the survival of enteric bacteria in the acidic gastric tract. it has been shown that eukaryotes can stabilize the intracellular ph by histone deacetylation. however, it remains unknown whether bacteria can utilize a reversible protein acetylation system to adapt to an acidic environm ...	2015	26070677
statistical approaches to developing a multiplex immunoassay for determining human exposure to environmental pathogens.	there are numerous pathogens that can be transmitted through water. identifying and understanding the routes and magnitude of exposure or infection to these microbial contaminants are critical to assessing and mitigating risk. conventional approaches of studying immunological responses to exposure or infection such as enzyme-linked immunosorbent assays (elisas) and other monoplex antibody-based immunoassays can be very costly, laborious, and consume large quantities of patient sample. a major li ...	2015	26070441
infection with salmonella enterica serovar typhimurium leads to increased proportions of f4/80+ red pulp macrophages and decreased proportions of b and t lymphocytes in the spleen.	infection of mice with salmonella enterica serovar typhimurium (salmonella) causes systemic inflammatory disease and enlargement of the spleen (splenomegaly). splenomegaly has been attributed to a general increase in the numbers of phagocytes, lymphocytes, as well as to the expansion of immature cd71+ter119+ reticulocytes. the spleen is important for recycling senescent red blood cells (rbcs) and for the capture and eradication of blood-borne pathogens. conservation of splenic tissue architectur ...	2015	26068006
in vitro and in vivo toxicological evaluations of methyl ferulate, methyl p-coumarate, and pulegone 1,2-epoxide.	toxicological screening of natural compounds for medicinal purposes.	2016	26067677
bacteria moving into focus of human cancer.	although bacteria have long been associated with human cancer, drawing causal relationships has been difficult. in this issue of cell host & microbe, scanu et al. (2015) provide evidence for a transforming activity of salmonella typhimurium on predisposed host cells, which can subsequently form tumors in a xenograft model.	2015	26067598
herd- and individual-level prevalences of and risk factors for salmonella spp. fecal shedding in dairy farms in al-dhulail valley, jordan.	salmonellosis is an important disease frequently associated with diarrhea in calves. from january to september 2009, a cross-sectional study involving 91 dairy farms was conducted to determine the prevalence of salmonella spp. infection in cattle in al-dhulail valley, jordan. a total of 910 calve and cow fecal samples were collected. information on farm management practices was obtained through personal interviews using a standardized questionnaire and was tested as risk factors for salmonella s ...	2015	26065698
molecular epidemiology of nontyphoidal salmonella in poultry and poultry products in india: implications for human health.	human infections with non-typhoidal salmonella (nts) serovars are increasingly becoming a threat to human health globally. while all motile salmonellae have zoonotic potential, salmonella enteritidis and salmonella typhimurium are most commonly associated with human disease, for which poultry are a major source. despite the increasing number of human nts infections, the epidemiology of nts in poultry in india has not been fully understood. hence, as a first step, we carried out epidemiological a ...	2015	26063942
diffusion and persistence of multidrug resistant salmonella typhimurium strains phage type dt120 in southern italy.	sixty-two multidrug resistant salmonella enterica serovar typhimurium strains isolated from 255 clinical strains collected in southern italy in 2006-2008 were characterised for antimicrobial resistance genes, pulsotype, and phage type. most strains (83.9%) were resistant to ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, and tetracycline (acssut) encoded in 88.5% by the salmonella genomic island (sgi1) and in 11.5% by the inh-like integron (bla oxa-30-aada1) and cata1, sul1, and tet ...	2015	26060815
a direct screen for c-di-gmp modulators reveals a salmonella typhimurium periplasmic ʟ-arginine-sensing pathway.	cyclic-di-gmp (c-di-gmp) is a bacterial second messenger that transduces internal and external signals and regulates bacterial motility and biofilm formation. some organisms encode more than 100 c-di-gmp-modulating enzymes, but only for a few has a signal been defined that modulates their activity. we developed and applied a high-throughput, real-time flow cytometry method that uses a fluorescence resonance energy transfer (fret)-based biosensor of free c-di-gmp to screen for signals that modula ...	2015	26060330
small molecules with big effects: cyclic di-gmp-mediated stimulation of cellulose production by the amino acid ʟ-arginine.	in this issue of science signaling, mills et al. show that the amino acid ʟ-arginine increases the concentration of the second messenger c-di-gmp in salmonella enterica serovar typhimurium through a specific diguanylate cyclase, leading to increased production of the exopolysaccharide cellulose, which is an extracellular matrix component of environmental and host-associated biofilms.	2015	26060328
effect of cell immobilization on the growth dynamics of salmonella typhimurium and escherichia coli at suboptimal temperatures.	predictive microbiology has recently acknowledged the impact of the solid(like) food structure on microbial behavior. the presence of this solid(like) structure causes microorganisms to grow as colonies and no longer planktonically as in liquid. in this paper, the growth dynamics of salmonella typhimurium and escherichia coli were studied as a function of temperature, considering different growth morphologies, i.e., (i) planktonic cells, (ii) immersed colonies and (iii) surface colonies. for all ...	2015	26057111
flagellin is required for host cell invasion and normal salmonella pathogenicity island 1 expression by salmonella enterica serovar paratyphi a.	salmonella enterica serovar paratyphi a is a human-specific serovar that, together with salmonella enterica serovar typhi and salmonella enterica serovar sendai, causes enteric fever. unlike the nontyphoidal salmonella enterica serovar typhimurium, the genomes of s. typhi and s. paratyphi a are characterized by inactivation of multiple genes, including in the flagellum-chemotaxis pathway. here, we explored the motility phenotype of s. paratyphi a and the role of flagellin in key virulence-associ ...	2015	26056383
tumor-targeting salmonella typhimurium a1-r in combination with trastuzumab eradicates her-2-positive cervical cancer cells in patient-derived mouse models.	we have previously developed mouse models of her-2-positive cervical cancer. tumors in nude mice had histological structures similar to the original tumor and were stained by anti-her-2 antibody in the same pattern as the patient's cancer. we have also previously developed tumor-targeting salmonella typhimurium a1-r and have demonstrated its efficacy against patient-derived tumor mouse models, both alone and in combination. in the current study, we determined the efficacy of s. typhimurium a1-r ...	2015	26047477
low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens.	orally administrated iron is suspected to increase susceptibility to enteric infections among children in infection endemic regions. here we investigated the effect of dietary iron on the pathology and local immune responses in intestinal infection models. mice were held on iron-deficient, normal iron, or high iron diets and after 2 weeks they were orally challenged with the pathogen citrobacter rodentium. microbiome analysis by pyrosequencing revealed profound iron- and infection-induced shifts ...	2015	26046550
antibacterial activity of ovary extract from sea urchin diadema setosum.	sea urchin gonad is considered as a highly prized delicacy in several countries. it is also rich in valuable bioactive compounds including polyunsaturated fatty acids (pufas) and β-carotene. this study was undertaken to examine the antimicrobial properties of the ovary extract from sea urchin diadema setosum against selected gram-negative and gram-positive bacteria.	2015	26044237
effect of milk fat content on the performance of ohmic heating for inactivation of escherichia coli o157:h7, salmonella enterica serovar typhimurium and listeria monocytogenes.	the effect of milk fat content on ohmic heating compared to conventional heating for inactivation of food-borne pathogens was investigated.	2015	26043029
antimicrobial effects of nisin, essential oil, and γ-irradiation treatments against high load of salmonella typhimurium on mini-carrots.	this study aimed at using essential oil (eo) alone or combined eo with nisin and γ-irradiation to control salmonella typhimurium during the refrigerated storage of mini-carrots. peeled mini-carrots were inoculated with s. typhimurium at a final concentration of approximately 7 log cfu/g. inoculated samples were coated by 5 different coating solutions: (i) nisin solution at final concentration of 10(3) iu/ml; (ii) mountain savory eo solution at 0.35%; (iii) carvacrol solution at 0.35%; (iv) mount ...	2015	26040299
comparative effects of ohmic and conventional heating for inactivation of escherichia coli o157:h7, salmonella enterica serovar typhimurium, and listeria monocytogenes in skim milk and cream.	ohmic heating has proven advantages over conventional thermal processing and novel thermal alternative technologies. in this study, the effect of ohmic and conventional heating for pasteurizing skim milk and cream was examined. all treatment conditions for ohmic and conventional heating were identical except for composition of the heating chamber. in most cases, the reduction of three pathogens did not differ significantly between ohmic heating and conventional heating at fixed treatment tempera ...	2015	26038915
soluble flagellin coimmunization attenuates th1 priming to salmonella and clearance by modulating dendritic cell activation and cytokine production.	soluble flagellin (sflic) from salmonella typhimurium (stm) can induce a th2 response to itself and coadministered antigens through ligation of tlr5. these properties suggest that sflic could potentially modulate responses to th1 antigens like live stm if both antigens are given concurrently. after coimmunization of mice with sflic and stm there was a reduction in th1 t cells (t-bet(+) ifn-γ(+) cd4 t cells) compared to stm alone and there was impaired clearance of stm. in contrast, there was no ...	2015	26036767
kinetics of bacterial inactivation by 405nm and 520nm light emitting diodes and the role of endogenous coproporphyrin on bacterial susceptibility.	photodynamic inactivation studies of microbial pathogens have focused on the use of an external photosensitizer or a precursor compound to eliminate bacteria. the present study investigated the inactivation kinetics of six bacterial pathogens by a 405nm light emitting diode (led) without the addition of any external compound. the role of endogenous coproporphyrin on the bacterial susceptibility to leds was also examined. pathogens were illuminated with leds at 25, 10 and 4°c for 9h and the inact ...	2015	26036659
antimicrobial activities of the combined use of cuminum cyminum l. essential oil, nisin and storage temperature against salmonella typhimurium and staphylococcus aureus in vitro.	foodborne diseases are considered as major health problems in different countries. concerns over the safety of some chemical preservatives and negative consumer reactions to them have prompted interest in natural alternatives for the maintenance or extension of food shelf life. in this respect, the combination of a plant essential oil and nisin has used for controlling the growth of foodborne pathogens as natural food preservative using the mathematical model.	2015	26034554
inactivation of escherichia coli o157:h7, salmonella typhimurium and listeria monocytogenes in apple juice at different ph levels by gaseous ozone treatment.	we investigated the effect of ozone treatment of apple juice at different ph levels for inactivation of escherichia coli o157:h7, salmonella typhimurium and listeria monocytogenes.	2015	26033289
synergistic effect of slightly acidic electrolyzed water and ultrasound at mild heat temperature in microbial reduction and shelf-life extension of fresh-cut bell pepper.	the objectives of this study were to evaluate the effect of combined treatments (slightly acidic electrolyzed water (saew), ultrasound (us), or mild heat (60°c)) on the growth of listeria monocytogenes and salmonella enterica serovar typhimurium in fresh-cut bell pepper, and the shelf-life and sensory quality (color and texture) were followed during storage at 4°c and 25°c. an additional 0.65, 1.72, and 2.70 log cfu/g reduction was achieved by heat treatments at 60°c for 1 min for dw, saew, and ...	2015	26032362
antimicrobial and cytotoxic activities from jatropha dioica roots.	the antimicrobial and cytotoxic activities of organic extracts obtained from roots of the medicinal plant jatropha dioica (euphorbiaceae) were investigated. in order to evaluate their antimicrobial activity, the organic extracts were tested against clinical isolates of the human pathogens bacillus cereus, escherichia coli, salmonella typhi, staphylococcus aureus, enterobacter aerogenes, enterobacter cloacae, salmonella typhimurium, cryptococcus neoformans, candida albicans, candida parapsilosis ...	2014	26031013
a mutagenicity and cytotoxicity study of limonium effusum aqueous extracts by allium, ames and mtt tests.	nowadays plants or plant extracts have become very important for alternative medicine. plants and their extracts have many therapeutical advantages but some of them are potentially toxic, mutagenic, carcinogenic and teratogenic. root, stem and leafparts of limonium effusum were used in this study and this species is an endemic species for turkey. mutagenic and cytotoxic effects of root, stem and leaf aqueous extracts were observed with allium, ames and mtt tests. allium root growth inhibition te ...	2015	26030975
outbreak of uncommon o4 non-agglutinating salmonella typhimurium linked to minced pork, saxony-anhalt, germany, january to april 2013.	in january 2013, the national reference centre for salmonella (nrc) detected a salmonellosis cluster in saxony-anhalt, germany, caused by uncommon o4 non-agglutinating, monophasic salmonella (s.) typhimurium dt193. circulating predominant monophasic s. typhimurium dt193 clones typically display resistance phenotype assut. we investigated common exposures to control the outbreak, and conducted microbiological investigations to assess the strains' phenotype.	2015	26030424
burkholderia cenocepacia and salmonella enterica arnt proteins that transfer 4-amino-4-deoxy-l-arabinose to lipopolysaccharide share membrane topology and functional amino acids.	we recently demonstrated that incorporation of 4-amino-4-deoxy-l-arabinose (l-ara4n) to the lipid a moiety of lipopolysaccharide (lps) is required for transport of lps to the outer membrane and viability of the gram-negative bacterium burkholderia cenocepacia. arnt is a membrane protein catalyzing the transfer of l-ara4n to the lps molecule at the periplasmic face of the inner membrane, but its topology and mechanism of action are not well characterized. here, we elucidate the topology of arnt a ...	2015	26030265
interferon-gamma and nitric oxide synthase 2 mediate the aggregation of resident adherent peritoneal exudate cells: implications for the host response to pathogens.	interferon-gamma (ifnγ), a key macrophage activating cytokine, plays pleiotropic roles in host immunity. in this study, the ability of ifnγ to induce the aggregation of resident mouse adherent peritoneal exudate cells (apecs), consisting primarily of macrophages, was investigated. cell-cell interactions involve adhesion molecules and, upon addition of ifnγ, cd11b re-localizes preferentially to the sites of interaction on apecs. a functional role of cd11b in enhancing aggregation is demonstrated ...	2015	26029930
antimutagenic and anticancer activity of al madinah alhasawy mint (mentha longifolia) leaves extract.	mentha is one of the genera of lamiaceae family. the aim of the present study was to evaluate the antimutagenic and anticancer activity of the water and methanolic extract of alhasawy mint (mentha longifolia), that grown in madina province, western region, saudi arabia using three different bioassays namely; brine shrimp bioassay, ames mutagenicity bioassay using 3 hist-salmonella typhimurium strains of different mutations (ta98, ta97 and ta100) and 2 reference mutagenic drugs nitrosopiperidine ...	2014	26027170
microbiological survey of birds of prey pellets.	a microbiological survey of 73 pellets collected from different birds of prey species housed at the wildlife rescue and rehabilitation center of napoli (southern italy) was performed. pellets were analyzed by culture and biochemical methods as well as by serotyping and polymerase chain reaction. we isolated a wide range of bacteria some of them also pathogens for humans (i.e. salmonella enterica serotype typhimurium, campylobacter coli, escherichia coli o serogroups). this study highlights the p ...	2015	26026881
quantitative evaluation of dna damage and mutation rate by atmospheric and room-temperature plasma (artp) and conventional mutagenesis.	dna damage is the dominant source of mutation, which is the driving force of evolution. therefore, it is important to quantitatively analyze the dna damage caused by different mutagenesis methods, the subsequent mutation rates, and their relationship. atmospheric and room temperature plasma (artp) mutagenesis has been used for the mutation breeding of more than 40 microorganisms. however, artp mutagenesis has not been quantitatively compared with conventional mutation methods. in this study, the ...	2015	26025015
rapid high-yield expression of a candidate influenza vaccine based on the ectodomain of m2 protein linked to flagellin in plants using viral vectors.	the extracellular domain of matrix protein 2 (m2e) of influenza a virus is a promising target for the development of a universal vaccine against influenza because m2e sequences are highly conserved among human influenza a strains. however, native m2e is poorly immunogenic, but its immunogenicity can be increased by delivery in combination with adjuvants or carrier particles. it was previously shown that fusion of m2e to bacterial flagellin, the ligand for toll-like receptor (tlr) 5 and powerful ...	2015	26022390
defining the core genome of salmonella enterica serovar typhimurium for genomic surveillance and epidemiological typing.	salmonella enterica serovar typhimurium is the most common salmonella serovar causing foodborne infections in australia and many other countries. twenty-one s. typhimurium strains from salmonella reference collection a (sara) were analyzed using illumina high-throughput genome sequencing. single nucleotide polymorphisms (snps) in 21 sara strains ranged from 46 to 11,916 snps, with an average of 1,577 snps per strain. together with 47 strains selected from publicly available s. typhimurium genome ...	2015	26019201
hamp domain rotation and tilting movements associated with signal transduction in the phoq sensor kinase.	hamp domains are α-helical coiled coils that often transduce signals from extracytoplasmic sensing domains to cytoplasmic domains. limited structural information has resulted in hypotheses that specific hamp helix movement changes downstream enzymatic activity. these hypotheses were tested by mutagenesis and cysteine cross-linking analysis of the phoq histidine kinase, essential for resistance to antimicrobial peptides in a variety of enteric pathogens. these results support a mechanistic model ...	2015	26015499
dissemination of inci2 plasmids that harbor the blactx-m element among clinical salmonella isolates.	the extended-spectrum-β-lactamase (esbl) determinant ctx-m-55 is increasingly prevalent in escherichia coli but remains extremely rare in salmonella. this study reports the isolation of a plasmid harboring the blactx-m-55 element in a clinical salmonella enterica serotype typhimurium strain resistant to multiple antibiotics. this plasmid is genetically identical to several known inci2-type elements harbored by e. coli strains recovered from animals. this finding indicates that inci2 plasmids har ...	2015	26014934
[comparative study of survival vibrio parahaemolyticus with escherichia coli and salmonella typhimurium in seawater].	in this work, survival tests are conducted in oligotrophic seawater using pathogenic bacterial strains: escherichia coli entéroagrégative, salmonella typhimurium and vibrio parahaemolyticus. after 26 days of incubation in seawater, the three bacterial strains are exposed to sunlight for nine hours. bacterial cells of the three strains, recovered at the end of the experiment by centrifugation were tested for their sensitivity to antibiotics and their enzymatic and metabolic profile (api 20e and 2 ...	2013	26012210
response of layer and broiler strain chickens to parenteral administration of a live salmonella typhimurium vaccine.	responses to the parenteral administration of a live aroa deletion salmonella serovar typhimurium vaccine given to three brown egg layer strains and two broiler strains were studied. twenty-five birds of each strain were reared together in floor pens to 6 weeks of age and then moved as individual strains to new floor pens and injected with 10(8) colony forming units (cfu) per bird of the vaccine bacteria intramuscularly or subcutaneously, 10(6) cfu per bird subcutaneously, or phosphate buffered ...	2015	26009756
synthesis, structural characterization and biological activity of novel cyclohexane-1,3-dione ligands and their metal complexes.	some new zn(ii) and cu(ii) complexes [cu(l1)(oac)2]∙h2o, [cu(l1)(no3)h2o]∙no3∙3.5h2o, [zn(l1)(no3)2]∙4.5h2o, [zn(l1)(oac)2(h2o)2]∙3h2o, [cu2(l2)(oac)4]∙2h2o∙2dmf, [cu(l2)2]∙2no3∙1.5dmf∙h2o, [zn(l2)2(no3)2]∙dmf and [zn2(l2)(oac)4(h2o)4]∙5h2o; l1 = 2-[2-(2-methoxyphenyl)hydrazono]cyclohexane-1,3-dione and l2 = 2-[2-(3-nitrophenyl)hydrazono]cyclohexane-1,3-dione were synthesized and characterized by ir, 1h-nmr,13c-nmr and ultraviolet (uv-vis.) spectroscopy, elemental analysis, magnetic susceptibili ...	2015	26007185
pegylated ofloxacin nanoparticles render strong antibacterial activity against many clinically important human pathogens.	the rise of bacterial resistance against important drugs threatens their clinical utility. fluoroquinones, one of the most important classes of contemporary antibiotics has also reported to suffer bacterial resistance. since the general mechanism of bacterial resistance against fluoroquinone antibiotics (e.g. ofloxacin) consists of target mutations resulting in reduced membrane permeability and increased efflux by the bacteria, strategies that could increase bacterial uptake and reduce efflux of ...	2015	26005932
detection of cell surface hydrophobicity, biofilm and fimbirae genes in salmonella isolated from tunisian clinical and poultry meat.	the aim of this study was to evaluate the ability of 15 serotypes of salmonella to form biofilm on polystyrene, polyvinyl chloride (pvc) and glass surfaces. .	2014	26005652
effect of different doses of manuka honey in experimentally induced mouse typhoid.	typhoid fever is a major cause of morbidity and mortality in the developing world. data from world health organization (who) shows that 21 million cases of typhoid occur globally every year and over 200,000 die each year; most of them at a very young age. the situation in pakistan is similar. typhi and other typhoidal salmonellae have developed resistance to chloramphenicol and other first line anti-typhoid. there is a rapid increase in multi-drug resistance (mdr) throughout the world. there is ...	2015	26004722
dominant suppression of inflammation via targeted mutation of the mrna destabilizing protein tristetraprolin.	in myeloid cells, the mrna-destabilizing protein tristetraprolin (ttp) is induced and extensively phosphorylated in response to lps. to investigate the role of two specific phosphorylations, at serines 52 and 178, we created a mouse strain in which those residues were replaced by nonphosphorylatable alanine residues. the mutant form of ttp was constitutively degraded by the proteasome and therefore expressed at low levels, yet it functioned as a potent mrna destabilizing factor and inhibitor of ...	2015	26002976
material properties and antimicrobial activity of polyhydroxybutyrate (phb) films incorporated with vanillin.	polyhydroxybutyrate (phb) was produced by bacillus mycoides dfc 1, isolated from garden soil. antimicrobial (am) films of phb were prepared by incorporating vanillin (4-hydroxy-3-methoxybenzaldehyde) from 10 to 200 μg/g of phb. the films were assessed for antimicrobial activity against foodborne pathogens and spoilage bacteria comprising of escherichia coli, salmonella typhimurium, shigella flexneri, and staphylococcus aureus and fungi such as aspergillus flavus, aspergillus fumigatus, aspergill ...	2015	26002697
mutagenicity and chemopreventive activities of astronium species assessed by ames test.	in the neotropical savannah, astronium species are used in popular medicine to treat allergies, inflammation, diarrhea and ulcers. given that natural products are promising starting points for the discovery of novel potentially therapeutic agents, the aim of the present study was to investigate the mutagenic and antimutagenic activities of hydroalcoholic extracts of astronium spp. the mutagenicity was determined by the ames test on salmonella typhimurium strains ta98, ta97a, ta100 and ta102. the ...	2015	26002624
a porcine reproductive and respiratory syndrome virus (prrsv) vaccine candidate based on the fusion protein of prrsv glycoprotein 5 and the toll-like receptor-5 agonist salmonella typhimurium fljb.	porcine reproductive and respiratory syndrome (prrs) is characterized by severe reproductive failure and severe pneumonia in neonatal pigs and is caused by prrs virus (prrsv). glycoprotein 5 (gp5) from prrsv is a key inducer of neutralizing antibodies. flagellin, a toll-like receptor 5 (tlr-5) agonist, is an effective inducer of innate immune responses. this study presents a novel prrsv vaccine candidate based on the adjuvant effect of salmonella typhimurium fljb fused with prrsv gp5.	2015	26001608
combination treatment of chlorine dioxide gas and aerosolized sanitizer for inactivating foodborne pathogens on spinach leaves and tomatoes.	the objective of this study was to evaluate the antimicrobial effect of chlorine dioxide (clo2) gas and aerosolized sanitizer, when applied alone or in combination, on the survival of escherichia coli o157:h7, salmonella typhimurium, and listeria monocytogenes inoculated onto spinach leaves and tomato surfaces. spinach leaves and tomatoes were inoculated with a cocktail of three strains each of the three foodborne pathogens. clo2 gas (5 or 10 ppmv) and aerosolized peracetic acid (paa) (80 ppm) w ...	2015	26001524
incorporation of nisin z and lauric arginate into pullulan films to inhibit foodborne pathogens associated with fresh and ready-to-eat muscle foods.	a combination of food grade compounds with edible films, used to inhibit foodborne pathogens associated with fresh or further processed muscle foods, is receiving considerable attention. in this study, pullulan films containing lauric arginate (lae) and nisin z (produced by lactococcus lactis subsp. lactis i8-7-3 and isolated from catfish gut), alone or in combination, were investigated for controlling foodborne pathogens on fresh and further processed muscle foods after long-term refrigerated s ...	2015	26001063
salmonella infection inhibits intestinal biotin transport: cellular and molecular mechanisms.	infection with the nontyphoidal salmonella is a common cause of food-borne disease that leads to acute gastroenteritis/diarrhea. severe/prolonged cases of salmonella infection could also impact host nutritional status, but little is known about its effect on intestinal absorption of vitamins, including biotin. we examined the effect of salmonella enterica serovar typhimurium (s. typhimurium) infection on intestinal biotin uptake using in vivo (streptomycin-pretreated mice) and in vitro [mouse (y ...	2015	25999427
periplasmic superoxide dismutase sodci of salmonella binds peptidoglycan to remain tethered within the periplasm.	salmonellae survive and propagate in macrophages to cause serious systemic disease. periplasmic superoxide dismutase plays a critical role in this survival by combating phagocytic superoxide. salmonella typhimurium strain 14028 produces two periplasmic superoxide dismutases: sodci and sodcii. although both proteins are produced during infection, only sodci is functional in the macrophage phagosome. we have previously shown that sodci, relative to sodcii, is both protease resistant and tethered w ...	2015	25998832
dual function of calcoco2/ndp52 during xenophagy.	during xenophagy, pathogens are selectively targeted by autophagy receptors to the autophagy machinery for their subsequent degradation. in infected cells, the autophagy receptor calcoco2/ndp52 targets salmonella typhimurium to the phagophore membrane by concomitantly interacting with lc3c and binding to ubiquitinated cytosolic bacteria or to lgals8/galectin 8 adsorbed on damaged vacuoles that contain bacteria. we recently reported that in addition, calcoco2 is also necessary for the maturation ...	2015	25998689
importance of sigma factor mutations in increased triclosan resistance in salmonella typhimurium.	salmonella enterica is the second most common foodborne pathogen. the use of biocides is crucial to prevent spread of foodborne pathogens, and it would be devastating for food safety if salmonella would become resistant to the disinfectants used. another concern is that exposure to disinfectants might lead to decreased susceptibility to antibiotics. the current study aimed to identify genetic changes causing high level triclosan resistance in s. enterica serovar typhimurium and evaluate how thes ...	2015	25986727
ascertaining the relationship between salmonella typhimurium and salmonella 4,[5],12:i:- by mlva and inferring the sources of human salmonellosis due to the two serovars in italy.	the current picture of human salmonellosis shows salmonella typhimurium and s. 4,[5],12:i:- as the most common serovars in italy. the aims of this study were to investigate the genetic relationship between these serovars, as well as to test the possibility of inferring sources of human salmonellosis due to s. typhimurium and s. 4,[5],12:i:- by using multilocus variable-number tandem repeat analysis (mlva) subtyping data. single isolates from 268 human sporadic cases and 325 veterinary isolates ( ...	2015	25983720
fluorofenidone inhibits macrophage il-1β production by suppressing inflammasome activity.	interleukin-1 beta (il-1β) is a potent pro-inflammatory and pro-fibrotic cytokine that plays an important role in renal fibrosis. fluorofenidone (akf-pd) is a novel pyridone agent that exerts a strong renal anti-fibrotic effect. we previously found that administration of akf-pd could significantly attenuate il-1β production in vitro and in vivo. however, the underlying mechanism is not fully understood. here we show that akf-pd has no effect on the expression of pro-il-1β in activated mouse macr ...	2015	25983199
high-throughput crispr typing of mycobacterium tuberculosis complex and salmonella enterica serotype typhimurium.	spoligotyping was developed almost 18 years ago and still remains a popular first-lane genotyping technique to identify and subtype mycobacterium tuberculosis complex (mtc) clinical isolates at a phylogeographic level. for other pathogens, such as salmonella enterica, recent studies suggest that specifically designed spoligotyping techniques could be interesting for public health purposes. spoligotyping was in its original format a reverse line-blot hybridization method using capture probes desi ...	2015	25981468
in vitro antibacterial activities and mechanism of sugar fatty acid esters against five food-related bacteria.	the objective of this study was to evaluate the antibacterial activities of sugar fatty acid esters, with different fatty acid and saccharide moieties, against five food-related bacteria including bacillus cereus, bacillus subtilis, staphylococcus aureus, escherichia coli and salmonella typhimurium. sucrose monocaprate showed the strongest antibacterial activity against all tested bacteria, especially gram-positive bacteria. the minimum inhibitory concentrations (mics) for gram-positive bacteria ...	2015	25977039
transnitrosation of non-mutagenic n-nitrosoproline forms mutagenic n-nitroso-n-methylurea.	n-nitroso-n-methylurea (nmu) is a potent carcinogen and suspected as a cause of human cancer. in this study, mutagenic nmu was detected by hplc after the transnitrosation of non-mutagenic n-nitrosoproline (np) to n-methylurea in the presence of thiourea (tu) under acidic conditions. the structure of nmu was confirmed by comparing (1)h nmr and ir spectra with that of authentic nmu after fractionation by column chromatography. furthermore, a fraction containing nmu formed by transnitrosation was m ...	2015	25975641
preliminary incidence and trends of infection with pathogens transmitted commonly through food - foodborne diseases active surveillance network, 10 u.s. sites, 2006-2014.	foodborne illnesses represent a substantial, yet largely preventable, health burden in the united states. in 10 u.s. geographic areas, the foodborne diseases active surveillance network (foodnet) monitors the incidence of laboratory-confirmed infections caused by nine pathogens transmitted commonly through food. this report summarizes preliminary 2014 data and describes changes in incidence compared with 2006-2008 and 2011-2013. in 2014, foodnet reported 19,542 infections, 4,445 hospitalizations ...	2015	25974634
electronic properties of environmental pollutants and their mutagenic activity: nitro derivatives of azaphenanthrenes.	the physico-chemical properties of nitroazaphenanthrene isomers: 4-nitro-9-azaphenanthrene (4-n-9-aph), 5-nitro-9-azaphenanthrene (5-n-9-aph), 6-nitro-4-azaphenanthrene (6-n-4-aph), 8-nitro-1-azaphenanthrene (8-n-1-aph), and 8-nitro-4-azaphenanthrene (8-n-4-aph) have been investigated theoretically using density functional theory (dft) calculations. equilibrium geometries, relative stability, ionization potentials, electron affinities, molecular electrostatic potentials, dipole moments, electric ...	2015	25974009
combined effects of organic acids and salt depending on type of acids and pathogens in laboratory media and acidified pickle.	in this study, the effectiveness of combining each of seven types of acids with 3% salt as a treatment against pathogens was investigated in laboratory media and acidified food.	2015	25973744
multidrug-resistant salmonella enterica serovar typhimurium monophasic variant 4,12:i:- isolated from asymptomatic wildlife in a catalonian wildlife rehabilitation center, spain.	wildlife can act as long-term asymptomatic reservoirs for zoonotic bacteria, such as salmonella. the prevalence and antimicrobial-susceptibility profiles of salmonella spp. were assessed in 263 cases in wildlife from 22 animal orders from a wildlife rehabilitation center in catalonia (ne spain), september 2013-may 2014. eleven of 263 tested animals were positive for salmonella spp., representing an overall prevalence of 4.2%. prevalences by taxonomic categories were 2% in mammals, 4.7% in birds, ...	2015	25973627
tumor-specifically hypoxia-induced therapy of spry1/2 displayed differential therapeutic efficacy for melanoma.	activation of receptor tyrosine kinase (rtk) signalling pathways is frequently correlated to cancer cell proliferation, angiogenesis and cell survival. sprouty (spry) proteins function as a physiological endogenous inhibitor of rtk signalling pathways, have been shown to be deregulated in most cancer cells. here, we demonstrated that over-expression of spry1 and spry2 inhibited b16f10 cell proliferation through g1 phase arrest in vitro, and spry2 showed more potent inhibitory effects than spry1. ...	2015	25973316
mathematical model of flagella gene expression dynamics in salmonella enterica serovar typhimurium.	flagellar assembly in salmonella is controlled by an intricate genetic and biochemical network. this network comprises of a number of inter-connected feedback loops, which control the assembly process dynamically. critical among these are the flia-flgm feedback, fliz-mediated positive feedback, and flit-mediated negative feedback. in this work, we develop a mathematical model to track the dynamics of flagellar gene expression in salmonella. analysis of our model demonstrates that the network is ...	2015	25972986
interaction of salmonella enterica serovar typhimurium with intestinal organoids derived from human induced pluripotent stem cells.	the intestinal mucosa forms the first line of defense against infections mediated by enteric pathogens such as salmonellae. here we exploited intestinal "organoids" (ihos) generated from human induced pluripotent stem cells (hipscs) to explore the interaction of salmonella enterica serovar typhimurium with ihos. imaging and rna sequencing were used to analyze these interactions, and clear changes in transcriptional signatures were detected, including altered patterns of cytokine expression after ...	2015	25964470
silver nanoparticles: correlating nanoparticle size and cellular uptake with genotoxicity.	the focus of this research was to develop a better understanding of the pertinent physico-chemical properties of silver nanoparticles (agnps) that affect genotoxicity, specifically how cellular uptake influences a genotoxic cell response. the genotoxicity of agnps was assessed for three potential mechanisms: mutagenicity, clastogenicity and dna strand-break-based dna damage. mutagenicity (reverse mutation assay) was assessed in five bacterial strains of salmonella typhimurium and echerichia coli ...	2015	25964273
prenylated polyphenolic compounds from glycyrrhiza iconica and their antimicrobial and antioxidant activities.	a new prenylated isoflavan, iconisoflavan (1), and a new prenylated isoflav-3-ene, iconisoflaven (2) were isolated from the roots of glycyrrhiza iconica together with four known ones namely (3s)-licoricidin (3), licorisoflavan a (4), topazolin (5) and glycycoumarin (6). the structures were elucidated on the basis of extensive spectroscopic analysis including 1d and 2d nmr as well as hr-ms. furthermore, the absolute configurations of compounds 1, 3 and 4 were established by electronic circular di ...	2015	25963162
outbreak of salmonella enterica serovar typhimurium phage type dt41 in danish poultry production.	salmonella enterica subspecies enterica serovar typhimurium (s. typhimurium) is one of the most prevalent serovars in europe - where both poultry and poultry related products are common sources of human salmonellosis. due to efficient control programs, the prevalence of s. typhimurium in danish poultry production is very low. despite this, during the past decades there has been a reoccurring problem with infections with s. typhimurium phage type dt41 in the danish poultry production without iden ...	2015	25962983
induction of crossover by introduction of aro554:tn10 into salmonella chromosome.	one of the ancient methods for the generation of bacterial mutants was to insert the composite transposable elements (e.g. tn10) flanked by desired gene sequences, into the bacterial chromosome. this mechanism of dna integrating into a chromosome can sometimes not only lead to the creation of desired mutants but also induced other recombination event within the chromosome. several studies have reported alterations such as deletion, insertion, inversion and both deletion/inversion in the bacteria ...	2015	25961422
(anti)mutagenic and immunomodulatory properties of quercetin glycosides.	quercetin-3-o-β-d-glucopyranoside (isoquercitrin) and quercetin-3-o-rutinoside (rutin) are common components of a normal human diet and are increasingly used in food supplements. here their effect on mutagenesis and immunity is shown.	2016	25960089
intraperitoneal administration of tumor-targeting salmonella typhimurium a1-r inhibits disseminated human ovarian cancer and extends survival in nude mice.	peritoneal disseminated cancer is highly treatment resistant. we here report the efficacy of intraperitoneal (i.p.) administration of tumor-targeting salmonella typhimurium a1-r in a nude mouse model of disseminated human ovarian cancer. the mouse model was established by intraperitoneal injection of the human ovarian cancer cell line skov3-gfp. seven days after implantation, mice were treated with s. typhimurium a1-r via intravenous (i.v.) or i.p. administration at the same dose, 5 × 10(7) cfu, ...	2015	25957417
a comparative study of bacterial and parasitic intestinal infections in india.	infectious diarrhea causes a major health problem in developing countries with significant morbidity and mortality. very often, rehydration therapy alone does not suffice, mandating the use of antimicrobial agents. however, rapidly decreasing antimicrobial susceptibility is complicating the matters.	2015	25954615
parallel evolutionary pathways to antibiotic resistance selected by biocide exposure.	biocides are widely used to prevent infection. we aimed to determine whether exposure of salmonella to various biocides could act as a driver of antibiotic resistance.	2015	25953808
genome sequence of salmonella enterica phage det7.	det7 is a myoviridae bacteriophage that gains entry into its salmonella enterica serovar typhimurium host cells by adsorbing to o-antigen polysaccharide. we report here the complete 157,498-bp sequence of its genome. det7, together with its vi01-like relatives, are distantly related to phage t4.	2015	25953168
composition, antimicrobial, antioxidant, and antiproliferative activity of origanum dictamnus (dittany) essential oil.	nowadays, there has been an increased interest in essential oils from various plant origins as potential antimicrobial, antioxidant, and antiproliferative agents. this trend can be mainly attributed to the rising number and severity of food poisoning outbreaks worldwide along with the recent negative consumer perception against artificial food additives and the demand for novel functional foods with possible health benefits. origanum dictamnus (dittany) is an aromatic, tender perennial plant tha ...	2015	25952773
control of pathogens in biofilms on the surface of stainless steel by levulinic acid plus sodium dodecyl sulfate.	the efficacy of levulinic acid (lva) plus sodium dodecyl sulfate (sds) to remove or inactivate listeria monocytogenes, salmonella typhimurium, and shiga toxin-producing escherichia coli (stec) in biofilms on the surface of stainless steel coupons was evaluated. five- or six-strain mixtures (ca. 9.0 log cfu/ml) of the three pathogens were separately inoculated on stainless steel coupons. after incubation at 21 °c for 72 h, the coupons were treated for 10 min by different concentrations of lva plu ...	2015	25950851