Publications

fathering from infancy to old age: a selective overview of recent psychoanalytic contributions.		2011	3107014
characterization of self-transmissible plasmids determining lactose fermentation and multiple antibiotic resistance in clinical strains of klebsiella pneumoniae.	the lactose fermentation (lac+) and antibiotic resistance (r+) phenotypes were conjugally transferred from klebsiella pneumoniae strains (k166, k182, k186, k218, and k220) to salmonella typhi, s. typhimurium, shigella flexneri, and vibrio cholerae. the genes for lactose fermentation and antibiotic resistance were located on the plasmids. further analysis of plasmid dna from these isolates indicated the presence of multiple plasmids (mr ranged less than 2.7 to 70 x 10(6)). the lac+r+ plasmids p16 ...	1987	3107002
changing pattern of bio and serotypes of vibrio cholerae 01 in rural bangladesh.		1987	3106666
[the pressor reaction induced by acupuncture and its physiological characteristics].		1986	3105917
partial splenic embolisation for hypersplenism of thalassaemia major: five year follow up.	six patients with thalassaemia major were treated by partial splenic embolisation as an alternative to splenectomy and followed up for five years. results were compared with those in a matched control group of seven patients treated by splenectomy. all patients treated by partial splenic embolisation showed a reduction in blood transfusion requirements comparable with those in the controls and which remained unchanged over the five years. serious infections that commonly occur in patients splene ...	2010	3105679
partial splenic embolisation for hypersplenism of thalassaemia major: five year follow up.	six patients with thalassaemia major were treated by partial splenic embolisation as an alternative to splenectomy and followed up for five years. results were compared with those in a matched control group of seven patients treated by splenectomy. all patients treated by partial splenic embolisation showed a reduction in blood transfusion requirements comparable with those in the controls and which remained unchanged over the five years. serious infections that commonly occur in patients splene ...	2010	3105679
a poor start for the health education authority.		2010	3105678
a poor start for the health education authority.		2010	3105678
basement membrane proteins produced by schwann cells and in neurofibromatosis.	mouse schwann cells and rat rn22 schwannoma cells cultured in the absence of neurons and fibroblasts produce typical basement membrane proteins. heparan sulfate proteoglycan (low density form), nidogen, and protein bm-40 were identified by radioimmunoassays, immunoblotting, and by immunoprecipitation after metabolic labeling. the cells also produce a laminin-like protein that differs from authentic laminin by a reduced a chain content and lack of antigenic determinants located in the long arm of ...	1986	3105390
desmopressin (ddavp) for treatment of disorders of hemostasis.	at a time when the acquired immunodeficiency syndrome as well as hepatitis and other blood-borne diseases are a threat to patients with bleeding disorders who need treatment with blood products, it is rewarding to realize that a number of these patients can be safely and effectively treated with their own desmopressin-stimulated f.viii:c and vwf. desmopressin is clinically useful for treatment of patients with moderate and mild hemophilia. the limits of the clinical indications are established b ...	2011	3104987
increased growth hormone response to clonidine in 6-hydroxydopamine-treated rats.	alpha 2-adrenergic receptors mediate adrenergic stimulation of growth hormone (gh) secretion in the rat. the gh response to the alpha 2-adrenergic agonist clonidine has thus been used as an index of alpha 2-adrenergic receptor responsiveness. pharmacologic manipulations known to upregulate alpha 2-adrenergic receptor sensitivity would then be expected to result in an enhancement of the gh response to clonidine. to test this hypothesis, rats were injected in the lateral ventricle with either 6-hy ...	1987	3104956
bio-antimutagenic effect of l-cysteine on diiodohydroxyquinoline-induced micronuclei in swiss mice.	the mutagenic potential of diiodohydroxyquinoline (dihq), a common anti-amebic drug, was tested using the in vivo micronucleus test in swiss mice following oral administration. it was found to be mutagenic in a dose-dependent manner. using the same model system, the bio-antimutagenic effect of the sulfhydryl compound l-cysteine against dihq was established.	2011	3104778
resolution of radiolabeled molecular species of phospholipid in human platelets: effect of thrombin.	resolution of individual molecular species of human platelet 1,2-diradyl-sn-glycero-3-phosphocholines and 1,2-diradyl-sn-glycero-3-phosphoethanolamines by reverse phase high pressure liquid chromatography (hplc) allowed a thorough analysis of those phospholipids labeled with [3h]arachidonic acid. approximately 54% and 16% of the total incorporated radiolabel was found in choline glycerophospholipids and ethanolamine glycerophospholipids, respectively, with ca. 90% of this being found in the 1,2- ...	1987	3104714
the protein receptor for cholerabacteriophage phi 149.	choleraphage phi 149 receptor activity was found in the outer membrane (om) protein of vibrio cholerae 154. receptor protein for phage phi 149 was separated from trypsin-treated om on a sephadex g-100 column. of the three peaks obtained, phage receptor activity was noted only in peak ii. sds-page showed that the mr of the protein was 35,000. the protein was heat-labile and protease-sensitive. the specificity of this protein as choleraphage phi 149 receptor was investigated by carrying out a prot ...	1987	3104086
salicylates inhibit paf-acether-induced rat paw oedema when cyclooxygenase inhibitors are ineffective.	the cyclooxygenase inhibitors indomethacin, piroxicam, ibuprofen, naproxen and flurbiprofen failed to block rat paw oedema induced by paf-acether, whereas aspirin and sodium salicylate were effective. two mixed cyclooxygenase and lipoxygenase inhibitors ndga, bw 755c and dexamethasone reduced oedema in a dose - dependently. the selective paf-acether antagonist, bn 52021, was effective against paf-acether at 5 - 20 mg/kg. the lipoxygenase derivates may be involved in paw oedema induced by paf-ace ...	1986	3103172
stimulation of arachidonic acid metabolism: differences in potencies of recombinant human interleukin-1 alpha and interleukin-1 beta on two cell types.	recombinant human interleukin-l (ril-1) alpha and beta, which have 26% homology in their amino acid sequence, stimulated arachidonic acid metabolism by squirrel monkey smooth muscle cells and rat liver cells; their relative effectiveness, however, varied with the two cells. recombinant il-1 alpha was 3 times more effective than ril-1 beta at stimulating arachidonic acid metabolism by the primate smooth muscle cells. recombinant il-1 alpha was 3 times less effective than ril-1 beta when measured ...	1986	3103171
[special radiology of the hand in renal osteopathy].	the different radiographical abnormalities of the hand with renal osteodystrophy are demonstrated. the soft tissue immersion low-energy x-ray technique allows early detection of macrostructural changes of spongy and compact bone, irregularities of the cortex, defects and pseudocysts, osteosclerosis as well as calcifications in the soft tissue and arterio sclerosis of patients with chronic renal failure. possible erroneous interpretations will be discussed.	2011	3103168
distribution of synaptophysin immunoreactivity in guinea pig heart.	the distribution of synaptophysin, an integral polypeptide of presynaptic vesicle membranes, was investigated in guinea pig heart by immunohistochemistry using monoclonal antibodies. synaptophysin immunoreactivity was found in varicose nerve terminals in all regions of the heart. dense networks of immunoreactive varicosities were found to surround the vasculature and to be located within the subendocardial layers of the atria and ventricles, the highest levels being seen in the innervation of th ...	1986	3102413
demonstration of an indomethacin-sensitive mechanism regulating immune reactivity in chagas' disease patients.	we investigated some aspects of the regulation of the immune response that were sensitive to the effect of indomethacin, an inhibitor of prostaglandin synthesis, in two groups of patients in the chronic phase of chagas' disease, and in normal controls. one group of patients was defined as being infected but with no clinical evidence of cardiac involvement, while the other showed electrocardiographic alterations that are characteristic of chagasic cardiomyopathy. the in vitro responses to mitogen ...	1986	3102400
influence of some inhibitors of arachidonic acid metabolism on oxytocin contractions in the isolated testicular capsule of the rat.	oxytocin (50-750 nm) contracted the isolated testicular capsule of the rat. mepacrine, a phospholipase a2 inhibitor (3 x 10(-5) m) and the lipoxygenase inhibitor nordihydroguaiaretic acid (10(-5) m) inhibited this response whereas the cyclooxygenase inhibitor, diclofenac sodium (10(-5) m), and the thromboxane synthetase inhibitor imidazole (10(-5) m) did not. it appears that metabolites of arachidonic acid dependent on lipoxygenase are involved in the contractile response of the rat testicular c ...	1986	3102257
acute and chronic pulmonary thromboembolism: current perspectives. part vii: current trends and newer developments.		2011	3102138
modulation of monocrotaline-induced hepatic genotoxicity in rats.	monocrotaline (mct), a hepatotoxic/hepatocarcinogenic pyrrolizidine alkaloid (pa) induced dna-dna interstrand crosslinks in a dose-dependent manner through 30 mg/kg. hepatic cytochrome p-450 has been shown to bioactivate mct to pyrrole derivatives which are thought to be responsible for these genotoxic lesions. we have hypothesized these lesions to be related to the adverse hepatic actions of mct and other pas. studies reported here investigated the effect of phenobarbital, a p-450 inducer, 2-di ...	1987	3102099
a new way of looking at manet: the revelations of radiography.		2011	3101950
medicine and managers.		2011	3101780
[characterization of pseudomonas aeruginosa isolates from intensive care units by sero-, lyso- and pyocin typing].		1986	3101296
etiological and clinical characteristics of diarrhea in young adults, with special reference to shigella gastroenteritis.		1986	3100995
a strain of multiform cryptococcus neoformans.		1986	3100152
alteration of lipoprotein profile during total parenteral nutrition with intralipid 10%.	eight patients were studied for lipoprotein profiles over a period of 3-7 weeks. four patients received total parenteral nutrition (tpn), including 1000 ml/day of intralipid 10%. three patients received fat-free tpn, and one patient was tube fed 1000 ml/day of intralipid 10% enterally. fat-free tpn lowered plasma lipid, especially low density lipoprotein (ldl) and high density lipoproteins (hdl). on the other hand, intravenous administration of intralipid 10% caused a marked increase of ldl, tog ...	2011	3099006
the effects of phorbol ester on alloantigen presentation.	b cells and ia+ thyroid cells fail to stimulate alloreactive t cells in a primary mixed leukocyte reaction (mlr) and fail to activate some allo-class ii (i-a) reactive t cell hybridomas. we now demonstrate that b cells can specifically stimulate a primary mlr in combination with the phorbol ester, pma, but not with interleukin 1 (il 1) or calcium ionophore. the primary mlr induced with b cells plus pma can be blocked by either monoclonal anti-i-a or anti-l3t4 antibodies. in contrast, thyroid cel ...	2011	3098841
myocardial oxygen supply during hypocapnia and hypercapnia in the dog.	it has been postulated that a coronary vasoconstriction during hypocapnia might be opposed by a compensating coronary vasodilatation due to impaired myocardial oxygen supply. the present study was performed first to examine whether a maximal decline in coronary sinus (cs) oxygen content was reached during hypocapnia. during hypercapnia a myocardial "over perfusion" has been demonstrated. the second purpose of the present study was to examine whether a myocardial "over perfusion" is essential to ...	1986	3098394
[characteristics of the functional antigens of neisseria meningitidis group b].	the work deals with the characterization of the functional antigens of n. meningitidis, group b. analysis of the total extract of n. meningitidis strain b16b6 with the use of sera obtained from patients with meningococcal infection, nasopharyngitis, salmonellosis, as well as from meningococcus carriers and healthy donors, by immune blotting techniques and the affinity isolation of the functional antigens indicate that protein antigen with a molecular weight of 13-15 kd is the main common antigen ...	1986	3098003
rash mutants deficient in gtp binding.	single amino acid substitutions were introduced into a region of the rash protein (residues 116, 117, and 119) homologous to a variety of diverse gtp-binding proteins. each of the mutant p21 proteins displayed a significant reduction (10- to 5,000-fold) in gtp binding affinity. activated rash proteins deficient in gtp binding were unaltered in their ability to morphologically transform nih 3t3 cells.	1986	3097518
arachidonic acid mobilization among phospholipids in murine mastocytoma p-815 cells: role of ether-linked phospholipids.	the ethanolamine-containing glycerophospholipids, choline-containing glycerophospholipids, and phosphatidylinositol fractions are major sources of arachidonic acid in murine mastocytoma p-815 cloned cells. the choline-linked fraction contained high arachidonic acid contents in 1-o-alkyl-2-acyl- (18%) and 1,2-diacyl-sn-glycero-3-phosphocholine (11%), with smaller amounts in 1-o-alk-1'-enyl-2-acyl species, whereas the arachidonic acid content of the ethanolamine-linked fraction was high in 1-o-alk ...	2011	3097226
interleukin 2 receptors are expressed by alveolar macrophages during pulmonary sarcoidosis and are inducible by lymphokine treatment of normal human lung macrophages, blood monocytes, and monocyte cell lines.	expression of receptors for il 2 was believed initially to be restricted to t cells after their activation by il 1 and antigen. however, recently il 2 receptors (il 2r) were demonstrated on activated b cells by using an anti-il 2r monoclonal antibody (anti-tac). in this study, we examined the capacity of cultured human alveolar macrophages, blood monocytes, and myelomonocytic (hl-60) or monoblast (u937) cell lines to bind three different anti-il 2r monoclonal antibodies before or after stimulati ...	1987	3097144
ventilatory changes during nitrous oxide isoflurane anaesthesia in children.	the changes in ventilatory variables under nitrous oxide isoflurane anaesthesia were studied in 10 children (mean age 46 +/- 13.4 months, mean weight 16.2 +/- 2.1 kg). measurements of flow and volume were performed by pneumotachography. pe'co2 was measured by capnography. the following variables (ve, vt, ti/ttot, vi, pe'co2) were measured or calculated under three increasing inspired isoflurane concentrations (0.75%, 1.5%, 2.25%). at each level of anaesthesia, ventilatory changes during exposure ...	2011	3096724
a stop transfer sequence recognizes receptors for nascent chain translocation across the endoplasmic reticulum membrane.	a stop transfer sequence derived from the extreme carboxyl terminus of membrane igm heavy chain has been shown to confer predictable transmembrane orientation to secretory proteins by aborting translocation of subsequently synthesized protein domains. here we demonstrate that, in certain peptide sequence contexts, the same stop transfer sequence is also capable of initiating domain translocation across the endoplasmic reticulum (er) membrane. translocation directed by a stop transfer sequence is ...	1986	3096576
[transmission of vibrio cholerae. possible role of the camel].	choleraic vibrio uses the moving means that man discovers to his own use. camels (passive and active vehicles of large quantity of crude water) were experimentally infected with a vibrio (tox. +) and an aeromonas (tox. +). suckling young camels eliminate them for 6 days and grown-up camels for 25 days. this experience, associated with the discovery of vibrio non 01 and shigella in the caravan camel dungs, lead them to become a potential vector of spreading from one oasis to another.	1986	3096512
the role of the t-cell receptor in thymocyte maturation: effects in vivo of anti-receptor antibody.	the t-cell receptor, which recognizes antigen plus a product of the major histocompatibility complex, has been postulated to drive t-cell maturation in the thymus by engaging major histocompatibility complex proteins expressed on thymic stromal cells. we tested this idea by injecting neonatal animals with an anti-receptor antibody, kj16, that binds to about 20% of t cells and is capable of blocking receptor function. in the presence of this antibody, mature t cells bearing the kj16 epitope faile ...	2011	3095843
case for diagnosis: leiomyoma with carneous degeneration.		2011	3095692
the effect of double filtration plasmapheresis on thyroid hormone economy and thyroid function.	five cases of rheumatoid arthritis (ra), two cases of systemic lupus erythematosus (sle), a case of mixed connective tissue disease (mctd), and a case of cold urticaria were treated with double filtration plasmapheresis (dfp). each aliquot of plasma was obtained at three different points of the dep circuit during the treatment and concentrations of thyroid hormones as well as thyroxine binding globulin (tbg) were measured. despite the removal of considerable amounts of triiodothyronine (t3), thy ...	1986	3095574
hemobilia: a cause of false-negative ductal dilatation.		2010	3095397
[kinetic studies on indium-111-oxine labelled lymphocytes from patients with chronic lymphocytic leukemia].		2011	3094311
intermediate-filament expression in thyroid gland carcinomas.	paraffin-embedded specimens of 200 primary thyroid carcinomas were examined immunohistologically for the expression of intermediate-filament (if) protein of the cytokeratin, vimentin and neurofilament type. in 36 cases, snap-frozen tissue was available, and double label immunofluorescence microscopy was performed in 23 of them. cytokeratin reactivity was found in all cells of all follicular, papillary and medullary carcinoma cases examined. using a monoclonal vimentin antibody, positive staining ...	2011	3094239
the hfr status of pseudomonas aeruginosa is stabilized by integrative suppression.	a temperature-sensitive mutant (dna-11) with the phenotype of a mutant defective in the initiation of dna replication, was isolated from an hfr-like fp2 donor of pseudomonas aeruginosa. reversion of its temperature-sensitive character was achieved by integrative suppression rather than by backmutation or an additional suppressor mutation. the dna-11 mutant proved to be helpful in stabilizing the hfr status of the original host.	1986	3093822
treating erythema chronicum migrans of lyme disease.	the efficacy of antibiotic treatment of 117 patients with erythema chronicum migrans of lyme disease was evaluated in terms of the necessity for retreatment and the prevention of the late manifestations of lyme disease. fifty-six patients with a minor form of the illness did not require retreatment and did not develop late manifestations following antibiotic treatment. three pregnant patients were included in this group. fourteen of sixty-one patients with a major form of the illness required re ...	2011	3093544
effect of aldose reductase inhibitor (sorbinil) on integration of polyol pathway, pentose phosphate pathway, and glycolytic route in diabetic rat lens.	this study examines the effect of an aldose reductase inhibitor (sorbinil) on the flux of specifically labeled glucose through alternative pathways of metabolism in the lens of normal and diabetic rats 1 wk after the induction of diabetes with alloxan. in the diabetic rat lens, there was an apparent increase in the flux of glucose through the pentose phosphate pathway (ppp), as measured by the difference in the yields of 14co2 from [1-14c]glucose and [6-14c]glucose [c1-c6], this value was 0.087 ...	1986	3093302
[heterogeneity of corynebacterium diphtheriae].		1986	3092513
distribution of the adult lactase phenotypes in turkey.	the adult lactase phenotype, lactose absorber or malabsorber, was determined using the lactose tolerance test with breath hydrogen assay in a group of young, healthy, male turks. out of a total of 470 subjects, 135 (28.7%) were lactose absorbers and 335 (71.3%) lactose malabsorbers. the frequency of the 'lactase suppression gene' in this population sample was 0.844 (s.d. 0.012). the frequency of lactase suppression in turkey is intermediate between that in southeast europe and that in agricultur ...	1986	3092418
laboratory transmission of schistosoma mansoni in brackish waters; survival and infectivity of cercariae.	schistosoma mansoni cercariae were exposed to various dilutions of sea water, both in the absence and in the presence of mice. it was found that whereas 100% and 75% sea water were lethal to the parasites, the parasites survived in lower concentrations of sea water. the lower the concentration the longer was the survival time. similarly, the rate of infection of mice decreased as the concentration of the sea water increased.	1986	3092417
inhibition of anti-cd3 (t3) antibody-induced activation of t cells by cyclosporine.		2011	3092413
toxigenic vibrio cholerae 01 infections--louisiana and florida.		1986	3092018
annual summary 1984. reported morbidity and mortality in the united states.		2011	3092006
a semi-quantitative assessment of the histopathology of oral lichen planus.	in a retrospective study of 112 cases, an attempt has been made to further delineate the histopathological parameters which are useful in making a diagnosis of oral lichen planus. the results of this study show that mononuclear infiltration beneath and adjacent to the epithelium, parakeratosis and degeneration of the basal layer of the epithelium were consistent features. linear regression analyses of the parameters studied provided partial support for a cell-mediated immune mechanism.	2010	3091793
the role of calcium in the rapid adaptation of an insect mechanoreceptor.	the femoral tactile spine of the cockroach is a rapidly adapting mechanoreceptor in which the response to a step displacement is a burst of action potentials lasting about 1 sec. this adaptation seems to occur during the encoding of action potentials from receptor current, since there is no evidence of adaptation in the receptor potential, and the adaptation can be demonstrated by direct electrical stimulation of the single sensory neuron in the spine. we have recently presented evidence for a c ...	2010	3091784
deafferentation elicits increased dopamine-sensitive adenylate cyclase and receptor binding in the olfactory tubercle.	removal of a major non-catecholaminergic output from the olfactory bulb elicits sprouting of dopaminergic axons in the olfactory tubercle. the functional consequences of this increased dopaminergic innervation are presently not known. this study examined the question of whether lesion-induced sprouting of dopaminergic axons is associated with changes in dopamine-sensitive adenylate cyclase and dopamine receptor density in the partially denervated olfactory tubercle. the results indicate that dop ...	1986	3091783
mitomycin c skin toxicity studies in mice: reduced ulceration and altered pharmacokinetics with topical dimethyl sulfoxide.	a series of toxicologic and pharmacokinetic studies were performed in balb/c mice administered intradermal (id) mitomycin c (mmc) at doses of .015 to 0.25 mg. dose-dependent skin ulcers were produced at clinically relevant mmc dose levels of .05 and .075 mg (3.6 to 10.7 mg/m2). these doses produced peak ulcers of 0.15 to 0.22 cm2, respectively, one to five days after injection. the integrated ulcer area x time values (area under the curve [auc] ulceration) were 0.89 and 3.11 cm2 x d. a large num ...	1986	3091779
mptp: clinical implications.	the concept of selective vulnerability of the basal ganglia is briefly reviewed historically, with respect to the possible implications of mptp and also the possible protective effects of selective moa inhibition in the treatment of parkinson's disease.	2010	3091763
a double-blind, randomized study of naproxen and acetylsalicylic acid after surgical removal of impacted lower third molars.	100 patients had an impacted lower 3rd molar surgically removed in a double-blind study. naproxen (500 mg b.i.d.) or acetylsalicylic acid (asa) (1 g t.i.d.) were administered to the patients. paracetamol was allowed as escape medication. 49 patients received naproxen and 51 asa. 4 patients from each group were excluded because they took other analgesics, took too few tablets, were lost to follow-up or had misunderstood the instructions. there was a significantly better over all analgesic effect ...	2010	3091717
galactosyltransferase purified from rat milk is distinct from the human and bovine enzyme.	n-acetylglucosaminide beta 1, 4-galactosyltransferase (ec 2.4.1.22) was purified from rat milk by affinity chromatography on n-acetylglucosamine-sepharose and alpha-lactalbumin-sepharose columns. the purified enzyme migrated as three polypeptides of relative molecular weight 59,000, 54,000, and 27,000 on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. antiserum raised against the 54k rat protein immunoprecipitated all three polypeptides, suggesting that they share common antigenic sit ...	1986	3091666
effects of the binding of myosin light chain kinase on the reactivities of calmodulin lysines.	the effects of the binding of smooth muscle myosin light chain (mlc) kinase on the microenvironments of different regions of calmodulin (cam) were investigated by comparing the acylation rate constants of the seven lysine amino groups of free cam with those of cam complexed with mlc kinase. equimolar amounts of cam and cam-mlc kinase complex were trace labeled with [3h]acetic anhydride in the presence of phenylalanine as a standard nucleophile. after completion of the reaction, equal amounts of ...	1986	3091599
risk of hypothermia in elderly patients with diabetes.	the incidence of admissions of patients with hypothermia was determined to examine whether hypothermia was more common in elderly patients with diabetes than in the general population after diabetic metabolic emergency cases had been excluded. a prospective survey of three accident and emergency departments identified 134 cases of hypothermia admitted from a catchment population of almost 157,000 aged 65 or over during the winters of 1981-2 to 1983-4. the predicted number of patients with diabet ...	2010	3091139
limitations in the use of 14c-glycocholate breath and stool bile acid determinations in patients with chronic diarrhea.	analysis of a modified 14c-glycocholate breath test on 165 consecutive in-patients being investigated for chronic diarrhea showed that the measurement of 14co2 between 3 and 6 h after oral dosing of 5 microci of 14c-glycocholic acid was of only limited use to distinguish between patients with crohn's disease (cd), idiopathic bile salt wastage (ibw), or ileal resection (ir) from those with the irritable bowel syndrome (ibs). continuing 14co2 collections for up to 24 h was of little more help in e ...	2011	3090133
goiter size and thyroid function in an endemic goiter area in northern italy.	thyroid function was studied in a large number of subjects residing in varsi, a town in the province of parma, italy. in this area, endemic goiter associated with moderate iodine deficiency [59 +/- 3 (+/- se) microgram iodine/g creatinine], as defined by who criteria, affects 65% of the population. serum t4, t3, thyroglobulin (tg), and tsh concentrations were measured by ria in 1218 subjects. the tsh response to trh was determined in 108 subjects selected randomly from the groups with different ...	1986	3090091
ru486 antagonizes the inhibitory action of progesterone on prostacyclin and thromboxane a2 synthesis in cultured rat myometrial explants.	a myometrial explant culture system was developed to investigate the effect of progesterone and the antiprogestagen ru486 on prostacyclin (pgi2) and thromboxane a2 (txa2) synthesis by the rat myometrium. after culture, eicosanoid synthesis was stimulated with arachidonic acid (aa) and the calcium ionophore a23187 (a23187). spontaneous release of eicosanoids was also studied. progesterone inhibited the spontaneous release of pgi2 and txa2 release by myometrial explants in a concentration- and tim ...	1986	3089760
reconstitution of the masking effect of sialic acid groups on sialidase-treated erythrocytes by the action of sialyltransferases.	glutardialdehyde-fixed or native rat erythrocytes were partially desialylated by the action of vibrio cholerae sialidase, resulting in the binding of these cells to homologous peritoneal macrophages. resialylation of these erythrocytes by purified alpha-(2----3)- or alpha-(2----6)-sialyltransferases with cmp-n-acetylneuraminic acid led to the incorporation of 60-80% of the enzymically released sialic acid. binding of the resialylated erythrocytes to peritoneal macrophages was reduced when compar ...	1986	3089604
an unusual case of gardnerella vaginalis septicaemia.		1986	3089498
the use of galactosyltransferase to probe nitrocellulose-immobilized glycoproteins for nonreducing terminal n-acetylglucosamine residues.	we report the use of udpgalactose:n-acetyl-d-glucosaminyl-glycopeptide 4-beta-d-galactosyl-transferase (ec 2.4.1.38), purified from bovine milk, to detect nonreducing terminal n-acetylglucosamine residues on glycoproteins immobilized on nitrocellulose by electrophoretic transfer from sodium dodecyl sulfate-polyacrylamide gels. soluble galactosyltransferase incorporates radiolabeled galactose from the substrate udp-[6-3h]galactose into the appropriate immobilized acceptor with high specificity. i ...	1986	3089057
characterization of cyanobacterial ferredoxin-nadp+ oxidoreductase molecular heterogeneity using chromatofocusing.	chromatofocusing has been used as an analytical tool to check preparations of the enzyme ferredoxin-nadp+ oxidoreductase (ec 1.18.1.2) purified in either the presence or absence of the serine protease inhibitor phenylmethylsulfonyl fluoride from the cyanobacterium anabaena sp. strain 7119. only one isoelectric species was found when the crude extract was processed in the presence of the protease inhibitor. nevertheless, when the inhibitor was omitted, four ionic forms of the enzyme--showing appa ...	1986	3089056
pneumothorax following insertion of a nasogastric tube.		2011	3089055
transdermal glyceryl trinitrate.		2011	3089054
intravenous anaesthesia with propofol and alfentanil. the influence of age and weight.	sixty healthy patients undergoing body surface surgery were anaesthetised with continuous infusions of propofol (200 micrograms/kg/minute) and alfentanil (0.25 microgram/kg/minute). additional bolus doses of propofol (20 mg) were given if movement occurred. the incidence of patient movement in response to skin incision was significantly less in patients over 45 years of age than in those below 45 years (p less than 0.05). maintenance dosage of propofol sufficient to abolish movement decreased wi ...	2011	3089052
propofol and alfentanil infusion. a comparison with methohexitone and alfentanil for major surgery.	in 42 patients undergoing major surgery, anaesthesia was induced by intravenous alfentanil 10 micrograms/kg together with methohexitone 1.5 mg/kg or propofol 2 mg/kg. an infusion of six times these doses per hour was then started; the rate was varied subsequently as indicated by the monitoring of arterial blood pressure, heart rate, eeg and frontalis electromyogram. the mean duration of infusion was 76.7 minutes for propofol and 74.5 minutes for methohexitone and the infusion was stopped about 1 ...	2011	3089051
caudal analgesia for perianal surgery. a comparison between bupivacaine and diamorphine.	seventy-three patients undergoing elective perianal surgery were randomly divided into a control group, a group who received a caudal injection of 20 ml bupivacaine 0.5% plain and a group who received diamorphine 2.5 mg in 10 ml normal saline by caudal injection; a comparison was then made of postoperative analgesia requirements. the bupivacaine group had better analgesia than the control group for the first 8 hours, after which there was no difference. the diamorphine group had better analgesia ...	2011	3089050
comparison of effects of fentanyl and alfentanil on intra-ocular pressure. a double-blind controlled trial.	the effects of fentanyl and alfentanil on intra-ocular pressure during anaesthesia were investigated in 50 consecutive patients in a double-blind controlled trial. both drugs produced a significant reduction in intraocular pressure (p less than 0.01). alfentanil produced significantly greater reduction (48.5 percent) than fentanyl (28.6 percent) (p less than 0.01). a small but statistically significant reduction in arterial pressure (15 percent approximately) and heart rate (18 percent approxima ...	2011	3089049
alfentanil supplemented anaesthesia for short procedures. a double-blind study of alfentanil used with etomidate and enflurane for day cases.	thirty-nine unpremedicated patients who presented for cystoscopy were given either alfentanil or saline in a random double-blind fashion immediately before anaesthesia with etomidate, nitrous oxide and enflurane. alfentanil significantly reduced myoclonus associated with etomidate. during anaesthesia, patients who received alfentanil had smaller minute volumes, lower respiratory frequencies, and smaller increases in heart rate. the incidence of apnoea was not significantly increased. after opera ...	2011	3089048
[relation between long-term artificial respiration and respiratory tract infection in 104 patients in a surgical intensive care unit].	the authors studied over a period of two years prospective connections between long-term artificial respiration and infections of the lower respiratory tract. a distinction was made between colonisation (rtc) and infection (rti). besides the incidence rate of rtc and rti the severity of the infection was recorded. the connections between the underlying disease, the duration of artificial respiration, the age of the patient and the antibiotic treatment with the pathogenesis of rtc and rti were st ...	2011	3089047
is bulimia an affective disorder?		2011	3089046
effect of thyrotropin-releasing hormone on vestibular compensation in primates.	continual administration of thyrotropin-releasing hormone (trh) (250 micrograms/kg/day) for 14 days using an osmotic mini-pump in unilateral labyrinthectomized squirrel monkeys induced accelerated vestibular compensation. decrease in total gait deviation counts and reduction of slow-phase eye velocity of spontaneous nystagmus were significantly faster in the trh-treated group as compared with the control group.	1986	3089045
complications of parenteral nutrition.	all hospitalized patients except infants (a total of 1,647 patients) who received central venous tpn solutions at ucdmc from 1981 through 1985 were studied to determine the incidence of complications from the use of tpn. a complication was considered to have occurred if the patient experienced obvious morbidity, mortality, or both; an event known to be deleterious, despite a lack of demonstrable morbidity; or premature loss of the central venous catheter. complications related to catheter placem ...	2011	3089044
the cell-saver and autologous transfusion: an underutilized resource in vascular surgery.	the vascular surgeon's best resource for blood transfusion is the patient's own blood. it is readily available for recycling, already precisely typed and crossmatched, and without the risk of transfusion-related diseases such as hepatitis and aids. the relative ease, safety, and cost-effectiveness of autologous blood transfusions, intraoperative autotransfusions, and postoperative autotransfusions has been shown in our hospital experience with 320 cases and in the literature. we predict that aut ...	2011	3089043
bone marrow aspirate culture superior to streptokinase clot culture and 8 ml 1:10 blood-to-broth ratio blood culture for diagnosis of typhoid fever.	we compared the sensitivities of bone marrow aspirate culture (bmac), 3 ml 1:4 and 8 ml 1:10 blood-to-broth ratio blood cultures (bc), 8 ml streptokinase clot culture (stkcc) and rectal swab culture (rsc) for isolating salmonella typhi and s. paratyphi a from 61 patients with typhoid or paratyphoid fever in jakarta, indonesia. bmac (92%) was significantly more sensitive than 8 ml bc (62%), 8 ml stkcc (51%), 3 ml bc (44%), rsc (56%) and the 19 ml combination of all three bc methods (71%). the com ...	1986	3089041
evidence that some membrane ligands modulate the plasmalemma fluidity of endothelial cells in culture.	the effect of some membrane ligands on the plasmalemmal fluidity of endothelial cells from bovine aorta in culture was investigated. the ligands used were: cationic ferritin (pi 8.5), soybean agglutinin, concanavalin a, wheat germ agglutinin, as well as glutaraldehyde at different concentrations. the fluidity probe employed was 1,6-diphenyl-1, 3, 5-hexatriene (dph) and the parameter determined to quantify the fluidity was fluorescence steady-state anisotropy. the optimum time interval required b ...	1986	3088620
effects of oral contraceptives on cholesterol.	studies have shown that the effects of progestins on lipid metabolism seem to be related to dose, not to the specific agent.	2011	3088271
posterior capsulitis of the temporomandibular joint.	posterior capsulitis, which is characterized by pain and inflammation localized above and behind the condyle of the mandible, usually develops as a result of premature contacts in dental occlusion. the pain at the affected side is related to the severe spasm of m. pterygoideus lateralis or the splinting action of the masticatory muscles. this condition can be readily treated by occlusal grinding of these premature contacts after a definite diagnosis. the amount of grinding on the teeth varies ac ...	2011	3088160
regulation of human gamma-interferon and beta-interferon gene expression in pha-activated lymphocytes.	two interferon (ifn) messengers were synthesized in phytohemagglutinin (pha)-activated lymphocytes: ifn-gamma mrna and a messenger hybridizing with the ifn-beta 2 probe. they were induced rapidly and declined at a stage when overall rna was still efficiently transcribed. the ifn-beta 2 mrna (15s) present in the lymphocytes was slightly different from its fibroblastic counterpart (14s). the kinetics of the accumulation and decay of both lymphocyte ifn messengers differed when assessed by hybridiz ...	1986	3088147
ultrastructure of cyst wall of sarcocystis of mus musculus, and reaction to cyst wall.		1986	3088138
gastric form of alpha chain disease.	a case of alpha chain disease, involving the stomach only, is reported in an algerian man suffering from epigastric pains. upper digestive tract fibreoptic endoscopy showed two antral ulcers and an ulcerative gastritis pattern, which promptly disappeared with cimetidine treatment. antral biopsies at a distance from the ulcers, but not of the ulcer crater itself, disclosed a dense infiltration of antral lamina propria by mature or sometimes atypical plasma cells. on transmural surgical antral bio ...	1986	3087826
sell your practice--the right way.		2011	3087718
[use of the radiosaturation analysis method in the diagnosis and monitoring of viral hepatitis].		1986	3087635
some properties of lipoxygenase activities in cytosol and microsomal fractions of mouse epidermal homogenate.	lipoxygenase activity in microsomal fraction of mouse epidermal homogenate was characterized in comparison with cytosol lipoxygenase activity. the major activity was identified as 12-lipoxygenase in microsomal fraction as well as in cytosol fraction by the analyses with high-performance liquid chromatography and gas chromatography-mass spectrometry. apparent km values of cytosol and microsomal 12-lipoxygenase for arachidonic acid were 5.0 microm and 6.2 microm respectively. apparent vmax values ...	1986	3085110
some properties of lipoxygenase activities in cytosol and microsomal fractions of mouse epidermal homogenate.	lipoxygenase activity in microsomal fraction of mouse epidermal homogenate was characterized in comparison with cytosol lipoxygenase activity. the major activity was identified as 12-lipoxygenase in microsomal fraction as well as in cytosol fraction by the analyses with high-performance liquid chromatography and gas chromatography-mass spectrometry. apparent km values of cytosol and microsomal 12-lipoxygenase for arachidonic acid were 5.0 microm and 6.2 microm respectively. apparent vmax values ...	1986	3085110
effects of prostaglandin synthesis inhibition on sympathetic-and parasympathetic-mediated coronary hemodynamic responses.	in chloralose-anesthetized dogs with the left circumflex coronary artery perfused at constant flow, the effects of indomethacin or naproxen on coronary and systemic responses to sympathetic and parasympathetic stimulation were evaluated. sympathetic stimulation was evoked either by 1-min carotid artery occlusion or by epinephrine (5 micrograms) or norepinephrine (5 micrograms) intracoronary administration. reflex or direct parasympathetic stimulation was produced by ouabain (40 micrograms) or ac ...	1986	3084760
protection by zinc against acetaminophen induced hepatotoxicity in mice.	the purpose of this investigation was to assess protection by zinc against acetaminophen induced hepatotoxicity and to evaluate possible mechanisms of protection. mice were treated with zinc (3 mg/kg, ip) or saline (ip) 48 and 24 hr before and sacrificed 12 hr after acetaminophen administration (375, 500, or 750 mg/kg, po). liver toxicity was then assessed by histological examination. the incidence of hepatotoxicity was significantly less at 375 and 500 mg/kg of acetaminophen in zinc treated ani ...	2011	3084325
inability of autoimmune mice with the lpr gene to spontaneously produce interleukin 3.	a recent report (palacios, r., eur. j. immunol. 1984. 14: 599) indicates that spleen cells from mrl-mpj-lpr/lpr mice spontaneously produce interleukin 3 (il 3) and suggests that this lymphokine could be responsible for promoting the lymphoid hyperplasia regulated by the lpr gene. the present study shows that splenocytes from several murine strains bearing the lpr gene do not spontaneously produce il3. this has been determined by measuring the amount of this lymphokine by a bioassay and by the de ...	2011	3084284
natural killer cell response to interferons.	the availability of recombinant interferons has facilitated a comparison of the in vitro effects of interferon-alpha and -gamma upon human natural killer (nk) cells. in the absence of interferon high and low nk responders exist. repeated testing of the same individuals revealed different but stable nk patterns to in vitro addition of interferon-alpha and -gamma furthermore, the nk cell response patterns differed depending on whether the interferons were administered in combination or separately. ...	1986	3084143
pharmacodynamics of tissue-type plasminogen activator characterized by computer-assisted simulation.	prospective characterization of pharmacodynamics of tissue-type plasminogen activator (t-pa) is needed for diverse clinical applications. accordingly, we used physiologically based, computer simulation of participating biochemical reactions in response to concentrations of circulating t-pa seen with infusions of 1 to 7 hr duration in 45 patients. predicted values were compared with those from a "training set" obtained in six patients given t-pa for coronary thrombosis and six receiving therapy f ...	2011	3084127
enumeration of b lymphocytes.		1986	3083188
metoclopramide for enhancing lactation.		2011	3083185
economic and policy analysis of university-based drug "detailing".	the cost-effectiveness of quality assurance programs is often poorly documented, especially for innovative approaches. the authors analyzed the economic effects of an experimental educational outreach program designed to reduce inappropriate drug prescribing, based on a four-state randomized controlled trial (n = 435 physicians). primary care physicians randomized into the face-to-face group were offered two individualized educational sessions with clinical pharmacists, lasting an average of 18 ...	2011	3083161
a multivariate approach for classifying hospitals and computing blended payment rates.	prospective payment for inpatient hospital care is based on the ideal that hospitals that produce similar outputs, as measured by the types of cases the hospital treats, should be paid similar prices. however, similar output is a multidimensional concept. thus operationalization of this ideal will ultimately require a more complex framework for determining hospital payment rates than currently employed at either the federal or state level. this article illustrates a multidimensional approach to ...	2011	3083160