Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| pertussis vaccines in japan. | 2010 | 3149848 | |
| base-sequence dependence of noncovalent complex formation and reactivity of benzo[a]pyrene diol epoxide with polynucleotides. | the base-sequence selectivity of the noncovalent binding of (+/-)-trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyr ene (bpde) to a series of synthetic polynucleotides in aqueous solutions (5 mm sodium cacodylate buffer, 20 mm nacl, ph 7.0, 22 degrees c) was investigated. the magnitude of a red-shifted absorbance at 353 nm, attributed to intercalative complex formation, was utilized to determine values of the association constant kic. intercalation in the alternating pyridine-pu ... | 2011 | 3149504 |
| characterization of the priming effects of human granulocyte-macrophage colony-stimulating factor on human neutrophil leukotriene synthesis. | human granulocyte-macrophage colony-stimulating factor (gm-csf) is an in vitro and in vivo stimulator of human bone marrow myelomonocytic precursor cells and mature granulocyte and macrophage effector cells. we have compared the effect of gm-csf on the synthesis of 5-lipoxygenase products induced by the chemotactic peptide fmet-leu-phe and the calcium ionophore a23187 in human neutrophils. although gm-csf alone did not stimulate detectable synthesis of products of the 5-lipoxygenase pathway, pre ... | 1988 | 3148964 |
| some thoughts about the evolution of pediatric endocrinology in the united states and illustrative selected advances. | 2010 | 3148256 | |
| general practitioner referral rates. | 2011 | 3147751 | |
| isolation of the early phase of chylomicron formation in intestinal epithelial cells of rats. | lipid is first observed electron microscopically in the rough endoplasmic reticulum of intestinal epithelial cells during active lipid absorption. we have been able to isolate this subcellular fraction by using discontinuous sucrose gradients of 0.25/0.86/1.11 m sucrose. a preliminary low speed centrifugation of mucosal homogenate removed the heavier subcellular organelles. the resulting supernatant was centrifuged at 5.25 x 10(6) x g.min. the pellet from this centrifugation was placed on top of ... | 1988 | 3147719 |
| an electron microscope study of the development of the exocrine and endocrine pancreas with special reference to intercellular junctions. | intercellular junctions in pancreatic acinar, duct and endocrine cells were studied by thin section and freeze-fracture methods in developing rats and mice. undifferentiated cells were joined by the zonula occludens and isolated fragments of tight junctional strands. small gap junctions were either occasionally associated with tight junctional strands or appeared independent of them. during the morphological differentiation of acinar cells, strands of the zonula occludens developed to form a com ... | 1988 | 3147689 |
| primate models for evaluation of aids vaccines. | 1988 | 3147661 | |
| [ablation of atrio-ventricular conduction by fulguration of the his bundle. proposal for a simplified technic. apropos of 70 cases]. | between 1982 and 1987, 70 patients (32 men, 38 women, aged from 45 to 93 years) underwent catheter ablation of his bundle and were followed up for more than 3 months. the disorders treated were atrial fibrillation, flutter of tachycardia (62 cases), junctional tachycardia (7 cases) and refractory atrial extrasystoles (1 case). the overall results were: early failure in 1 case, late death in 3 cases, persistent high degree av block in 53 cases (75 p. 100), 1st degree av block in 9 cases (12 p. 10 ... | 2011 | 3147638 |
| [physiopathologic justification of long-term oxygen therapy in chronic respiratory insufficiency]. | 2011 | 3147599 | |
| use of a microcomputer relational database in a long-term-care psychiatric facility. | 2011 | 3147597 | |
| the development of immunological relationship between mother and fetus under physiological and pathological conditions. | on the basis of results of our research and review of literature, the complex of immuno logical influences, operating during the development of the human fetus, were evaluated. it is obvious that during the early stages of pregnancy the conceptus is protected by non-specific mechanisms, i.e. hormonally (hcg, progesterone) and by certain properties of the trophoblast (barrier function, immunologically inert surface). specific immunological tolerance is formed by gradual penetration of trophoblast ... | 1988 | 3147589 |
| adverse reaction of acetaminophen as an alternative analgesic in a.a.s. triad. | the syndrome of a.a.s. triad consisting of an intolerance to analgesics such as aspirin, bronchial asthma and nasal polyps, is every day more frequent. during the last years, the use of acetaminophen as an analgesic-antipyretic alternative in patients with a.a.s. triad has been imperative. however, there are already publications that show reversible bronchial obstruction symptoms similar to the ones produced by a.a.s., though of less intensity. a study was performed in 32 patients diagnosed of a ... | 2011 | 3147588 |
| the effect of hypophysectomy on inhibin production by adult rat ovaries: changes in ovarian inhibin gene expression and serum inhibin. | we have investigated the effect of hypophysectomy on adult rat ovarian inhibin alpha- and beta a-subunit mrna, serum inhibin, and circulating gonadotrophin levels. immediate declines in ovarian inhibin gene expression and serum inhibin were observed following hypophysectomy, with a nadir on day 4. however, inhibin synthesis determined by these parameters was still apparent at 16 days post-hypophysectomy. gonadotropin levels were suppressed following hypophysectomy and the fall in inhibin product ... | 1988 | 3147584 |
| the impact of long-term lithium treatment on renal function and structure. | the effects of long-term lithium treatment on kidney function have been intensively studied. both retrospective and prospective functional studies have shown that prolonged lithium treatment has a profound influence on renal tubular function, and may result in reduced renal concentrating capacity and increased urine volumes. more important, long-term lithium administration at non-toxic serum levels has little demonstrable or no effect at all on glomerular function. prospective studies found no e ... | 2011 | 3147581 |
| effect of glycosylation inhibitors on the binding of insulin and lectins and on hormonal imprinting in tetrahymena. | treatment of the unicellular tetrahymena with inhibitors of glycosylation (glucosamine or 2-fluoro-2-deoxy-d-glucose) leads, with a few exceptions, to enhancement of the binding of fitc-labelled insulin and lectins (con-a, helix, datura). the development of insulin-evoked imprinting (i.e., the enhancement of binding at subsequent contacts) is not prevented by the administration of glucosamine. meanwhile the administration of fluoroglucose results, on its own, in enhanced binding. this increased ... | 2011 | 3147568 |
| the simavi-tanga project for self-help in health. an assessment of a comprehensive primary health care programme. | primary health care (phc) is the major strategy for achieving the goal of health for all. lessons are to be learnt from a variety of experiences. the simavi-tanga project for self-help in health is a comprehensive phc-project with a limited input of external financial and advisory assistance. the short term outcome in terms of effectiveness and efficiency does not differ essentially from comparable tanzanian projects with a higher degree of external input. the main limiting factors with regard t ... | 1988 | 3147549 |
| the venous blood-flow of the flexor aspect of the human forearm. clinical relevance to the distally-pedicled forearm flap. | in the distally-pedicled radial island flap a reverse venous flow was observed. in 20 cadaver extremities the veins of the lower arms were perfused and dissected and the island flaps elevated. the 3 venous systems are described here according to the number, site and shape of the valves and the venous flow from the flap is also discussed. | 1988 | 3147536 |
| [the laboratorio nacional de referencia de mycobacteria y tuberculosis in the antituberculosis campaign in cuba]. | 1988 | 3147500 | |
| [transperitoneal transport of methotrexate: in vitro studies]. | 1988 | 3147495 | |
| nicotine tolerance: an analysis of the time course of its development and loss in the rat. | the time course of the development and loss of tolerance to nicotine was measured in female rats that were injected subcutaneously (sc), twice daily with 1.6 mg/kg nicotine. tolerance to nicotine-induced decreases in locomotor activity and body temperature were observed. tolerance to the effects of nicotine on both of these measures developed rapidly, with maximal changes occurring within 2-4 days after initiation of treatment. the binding of l-[3h]-nicotine was measured in six brain regions. ch ... | 1988 | 3147478 |
| the chlordiazepoxide/pentylenetetrazol discrimination: characterization of drug interactions and homeostatic responses to drug challenges. | rats were trained to discriminate chlordiazepoxide (cdp) from pentylenetetrazol (ptz) in a two-lever food motivated discrimination task. training drug doses were adjusted until subjects emitted approximately 50% of their responses on each of the two drug-appropriate levers during saline injection tests. tests that followed injection of cdp/ptz combinations illustrated a reciprocal antagonism between the two drugs. saline-injection tests that followed large dose injections of cdp revealed a perio ... | 1988 | 3147473 |
| on the role of the dorsal noradrenergic bundle in learning and habituation to novelty. | in experiment 1, the performance of vehicle control rats and rats with 6-hydroxydopamine-induced lesions of the dorsal noradrenergic bundle (db) was examined in acquisition and extinction of bar pressing and in spontaneous and food-reinforced alternation in a t-shape maze. plasma corticosterone levels in basal conditions, after chronic food restriction, after transportation to a novel environment, and after sessions of either rewarded or nonrewarded bar pressing were assayed. db lesions produced ... | 1988 | 3147459 |
| nad(p)h dehydrogenase (quinone) from sporotrichum pulverulentum. | 2011 | 3147357 | |
| [characteristics of changes in cardiac output and blood gas composition in humans in modeling the effects of weightlessness]. | 2011 | 3147343 | |
| [pigmented neurofibrosarcoma in a patient with von recklinghausen's disease: clinical and ultrastructural studies]. | 2011 | 3147337 | |
| cellular immunity after oral administration with v. cholerae. | 1988 | 3147307 | |
| [ultrahistochemical demonstration of blood group b substances on human erythrocytes with a lectin from salmo gairdneri rich]. | from the roe of salmo gairdneri rich., a lectin was isolated which agglutinates specifically human erythrocytes of blood group b. for cytochemical labelling of the blood group substance b on the surface of human erythrocytes, an indirect approach was chosen. by means of a polyclonal antibody from the rabbit against the b-specific fish lectin, electronmicroscopic presentation was performed with protein a gold using a multistep method. for quantification gold labelling was partially followed by a ... | 1988 | 3146853 |
| characterization of a chimaeric plasminogen activator obtained by insertion of the second kringle structure of tissue-type plasminogen activator (amino acids 173 through 262) between residues asp130 and ser139 of urokinase-type plasminogen activator. | a chimaeric recombinant plasminogen activator (rscu-pa- k2) obtained by insertion of the second kringle (k2) of tissue-type plasminogen activator (t-pa) (amino acids 173-262) between residues asp130 and ser139 of single chain urokinase-type plasminogen activator (scu-pa) was purified from the conditioned medium of mouse myeloma cells transfected with the previously described plasmid pulb9137 (piérard et al., j. biol. chem. 262, 11771-11778, 1987). approximately 22 micrograms of purified protein ... | 1988 | 3146822 |
| tumor necrosis factor and hiv p24 antigen levels in serum of hiv-infected populations. | tumor necrosis factor (tnf) and hiv p24 antigen levels were determined in the serum of intravenous drug abusers (ivdas), homosexuals, and patients with lymphadenopathy or acquired immune deficiency syndrome (aids). the mean tnf level in the serum of normal controls was 12 +/- 5 compared to 112 +/- 25 pg/ml in the serum of hiv-seronegative asymptomatic ivdas. this increase of tnf may be due to the variety of infections that these people are exposed to persistently. the mean tnf level in the serum ... | 1988 | 3146635 |
| [a new sensitivity test for substances used as antiseptics or disinfectants. i. biological studies]. | in this first article, the authors present a fast method of determining the bactericide and bacteriostatic power of the germs, based on the disparition of the succino-dehydrogenase activity of a bacterium, objectified by a neotetrazolium chloride reaction. this reaction allows a colorimetric qualitative and quantitative determination of the activity of a preparation and the duration of its contact with the bacteria. this method allows a study in electronic microscopy which will be published in a ... | 1988 | 3146445 |
| effects of excess vitamin a and canthaxanthin on salivary gland tumors. | the effects of feeding semipurified diets supplemented with excess retinyl palmitate (20,000 and 100,000 iu/kg), beta-carotene (250 mg/kg), and canthaxanthin (250 mg/kg) on 7,12-dimethylbenz[a]anthracene (dmba)-induced salivary gland tumors were studied in rats. none of the dietary supplements had a significant effect on tumor incidence. tumor weights, however, tended to be lower in rats fed the dietary supplements compared with the controls. the incidence of tumor-bearing rats with large tumors ... | 1988 | 3146058 |
| kinetic factors influencing the dissolution behavior of calcium oxalate renal stones: a constant composition study. | a constant composition method has been used to examine the dissolution kinetics of calcium oxalate renal stones over a wide range of undersaturation in vitro. demineralization experiments have been carried out with the concentrations of calcium and oxalate ions and ionic strength (hence the solution undersaturation) held constant by the potentiometrically controlled addition of medium electrolyte solution as diluent, triggered by a calcium ion electrode. kinetic data for renal stones have been c ... | 2011 | 3145798 |
| is vitellogenin an ancestor of apolipoprotein b-100 of human low-density lipoprotein and human lipoprotein lipase? | vitellogenin, an ancient animal protein, is the major yolk protein of eggs, where it is used as a food source during embryogenesis. here it is shown that vitellogenins, including those from the invertebrates caenorhabditis elegans and drosophila melanogaster, contain domains that are homologous with parts of apolipoprotein b-100 (apob-100) of human low-density lipoprotein and human lipoprotein lipase. as vitellogenins are likely to have been used by invertebrates during embryogenesis well before ... | 1988 | 3145737 |
| [intravenous combination anesthesia using alfentanil in infants]. | intravenous anesthesia is a method rarely used during infancy. only neuroleptanalgesia has a number of indications, especially in major surgery and for seriously ill children. there are several advantages of inhalation anesthesia in infancy: good control of anesthesia because of low fat-muscle mass, low functional residual capacity, relatively increased alveolar ventilation, and increased cardiac output. potential disadvantages of inhalation anesthesia in infancy are numerous: the necessity of h ... | 2011 | 3145688 |
| [bloemendaal, the hague]. | 2011 | 3145626 | |
| chemical modification of the antitumor antibiotic glidobactin. | a variety of glidobactin analogs modified at the fatty acid, l-threonine and nucleus moieties of the molecule were synthesized and their structure-activity relationships examined. the antitumor and antifungal activity was greatly influenced by modification of the fatty acid glidobactin, with the dodecanoyl and tetradecanoyl analogs exhibiting better antitumor activity than the parent antibiotics. replacement of the l-threonine with other amino acids greatly reduced the activity and reduction of ... | 2011 | 3145257 |
| the effects of norplant-2 rods on clinical chemistry in singaporean acceptors after 1 year of use: haemostatic changes. | a longitudinal study of coagulation parameters was carried out on 100 singapore acceptors using the levonorgestrel subdermal implants norplant-2 rods for contraceptive purposes. at the end of 1 year of use, results from this on-going study indicates that these acceptors have an enhanced potential for hypercoagulation with a significant shortening of their prothrombin time and activated partial thromboplastin time. they also have an increased predisposition to thrombosis as evidenced by significa ... | 1988 | 3145169 |
| crystals in calcified epiphyseal cartilage and cortical bone of the rat. | the size of hydroxyapatite (hap) crystals in calcified cartilage and cortical bone of the rat has been studied and compared with that of synthetic poorly crystalline hydroxyapatite (pcha). crystal size was determined by x-ray diffraction and selected-area dark field imaging, and their elemental compositions were determined by emission spectroscopy. the crystal size of cartilage, bone, and pcha were found to be between 120 and 170 a in length by 50 a in width as determined by both x-ray diffracti ... | 1988 | 3145127 |
| the critically ill surgical patient: nutritional considerations. | the nutritional care of the patient in the surgical intensive care unit is one of the most challenging in the field of nutritional support. each patient must be assessed individually and specific goals of nutritional support established. specialized nutritional solutions may be needed for the patient with significant renal, hepatic, or pulmonary disease, as well as patients in a chronic septic state. knowledge of the infectious and metabolic complications that frequently occur in this population ... | 2007 | 3145109 |
| immunoglobulin administration into cerebral subarachnoid space in a child with hypogammaglobulinemia and aseptic meningoencephalitis. | 2011 | 3144830 | |
| epithelioid granulomatosis with initial and predominant manifestation in spleen. morphological and immunohistochemical analysis of six cases. | in six patients with systemic symptoms, four of which had lymphoplasmacytic infiltrates in the bone marrow splenectomy was performed because of suspected malignant lymphoma, with resolution of clinical symptoms. the spleen showed epithelioid granulomas, and neither splenic tissue nor clinical follow-up revealed evidence of malignant lymphoma. immunohistochemical analysis documented an identical phenotype in epithelioid and giant cells as well as in large numbers of cd4 + lymphocytes and s100 + i ... | 2011 | 3144805 |
| pseudoanaphylaxis: two case studies. | 2011 | 3143943 | |
| [hemolysin production by vibrio cholerae non-o1 and o1 el tor determined by biological and immunological activities]. | 1988 | 3143787 | |
| current status of clinical islet transplantation. | 2011 | 3143652 | |
| pseudo grey platelet syndrome--grey platelets due to degranulation in blood collected into edta. | we have studied a woman with a history of mild bruising and bleeding, with a normal platelet count and normal clotting factors, who had platelets that appeared grey when stained and viewed under the microscope. unlike the grey platelet syndrome, the abnormality was only evident when blood had been collected into edta and not when citrate or heparin was used as anticoagulant. this 'pseudo grey platelet syndrome' was associated with platelet dense body and alpha granule secretion with no aggregati ... | 2011 | 3143601 |
| restriction endonuclease analysis of brucella abortus. | the restriction endonuclease profiles of bacterial dna from brucella abortus isolates were evaluated. it was not possible to distinguish between vaccine strain 19 and virulent (biotype 1 and biotype 2) strains of b abortus. restriction endonuclease analysis is therefore not a suitable epidemiological tool in bovine brucellosis investigations. the genetic homogeneity of the brucella genus was reinforced by these findings. | 1988 | 3143134 |
| [the role of the nurse and her education between the past and the future. analysis of realities in calabria]. | 2011 | 3143127 | |
| effect of cholecystectomy on common bile duct diameters: a longitudinal prospective ultrasonographic study. | the medium-term effect of cholecystectomy on common bile duct diameters (cbd) was investigated prospectively in 64 patients with gallstone disease examined by ultrasonography immediately before and 27 months to 39 months after the operation. in 32 patients with chronic cholecystitis and patent cystic ducts, cbd diameters increased slightly (median 4.6 mm pre- and 5.3 mm postoperatively; p less than 0.05). a group of 19 patients with acute cholecystitis or cystic duct occlusion showed a significa ... | 2009 | 3142922 |
| guidelines for the use of vitamins, trace elements, calcium, magnesium, and phosphorus in infants and children receiving total parenteral nutrition: report of the subcommittee on pediatric parenteral nutrient requirements from the committee on clinical practice issues of the american society for clinical nutrition. | 2011 | 3142247 | |
| [short-latency brain stem evoked potentials to acoustic stimulation in posttraumatic epilepsy]. | as a result of a comprehensive analysis of posttraumatic epileptic patients the changes in brain stem acoustic evoked potentials are described. | 2011 | 3142192 |
| intracellular injection of ca2+ chelator does not affect spike repolarization of cat spinal motoneurons. | both intra- and extracellular injections of tetraethylammonium (tea) prolonged the spike repolarization of motoneurons in the spinal cord of cats under pentabarbitone anaesthesia, but did not depress the afterhyperpolarization (ahp). intracellular injections of egta and the fast-acting ca2+ chelator, bapta, greatly depressed the ahp, but the spike shape remained unchanged. extracellular applications of cd2+ had similar effects. these observations suggest that a ca2+-dependent k+ outward current ... | 1988 | 3141006 |
| characteristics of polymerized pyridoxylated hemoglobin. | polymerization of sfh-p currently provides the only approach that leads to a hemoglobin solution that approximates the o2 carrying capacity of whole blood and can be infused without altering the cop of plasma. it appears to have an adequate o2 loading and unloading characteristic and a greatly improved intravascular half-life. in addition, stable shelf-life at 4 degrees c of greater than five months, makes it a prime candidate for future pre-clinical and clinical investigations. | 1988 | 3140917 |
| [methohexital/alfentanil-thiopental/alfentanil for total intravenous anesthesia for direct laryngoscopy with 100% o2 jet ventilation]. | for the direct laryngoscopy and microscopic examination of the larynx with exploratory excision and pulpectomy using low frequency jet-ventilation with 100% oxygen we used total intravenous anaesthesia with a strong acting opioid and a barbiturate. because the achievement of sufficient reflexes and a high degree of vigilance postoperatively are to be aimed, methohexitone (m) and thiopentone (t) were investigated in the regard of the suppression of vigilance in the postoperative period. 40 patien ... | 2011 | 3140687 |
| asnr presidential address, 1988. | 2011 | 3140646 | |
| [hemodynamic effect of certain vasodilators on the major and lesser circulation]. | 2011 | 3140174 | |
| disruption of development on triatominae bugs by action of juvenile hormone analogues. | 2011 | 3138739 | |
| a case of homocystinuria. | 2011 | 3138571 | |
| gastroenteritis due to vibrio cholerae el tor ogawa. | 1988 | 3138473 | |
| posttranslational modifications of the ia-associated invariant protein p41 after gene transfer. | biochemical analysis of a rat fibroblast cell clone, transfected with the murine ia associated invariant chain gene, demonstrates the expression of a family of proteins. this indicates that all members of the invariant protein family are derived from the same gene. the proteins p41, ii, p27, p25, and p10, synthesized in the transfectant cell line, are identical with the invariant proteins previously shown to associate noncovalently with ia antigens. these proteins are identified by immunoprecipi ... | 1988 | 3137970 |
| expectancy effects on respiration during lactate infusion. | the effect of lactate infusion on pco2 and respiration rate was studied in two differently instructed groups of healthy volunteers in a double-blind, placebo-controlled, cross-over study. both groups showed a significant decrease in alveolar pco2 after lactate but not after placebo. this was accompanied by an increase in respiration rate in those subjects who had expected to become anxious and by a decrease in respiration rate in those who had expected to experience pleasant excitement. | 2011 | 3137634 |
| value of cerebrospinal fluid analysis in the differential diagnosis of meningitis: a study in 710 patients with suspected central nervous system infection. | a prospective study to determine the value of cerebrospinal fluid analysis in the differential diagnosis of meningitis was performed in 710 consecutively observed patients, both children and adults, who underwent lumbar puncture due to suspected central nervous system infection. diagnoses included acute or presumed bacterial meningitis (n = 79), acute or presumed viral meningoencephalitis (n = 218), acute unclassified meningitis (n = 6), other infections of the central nervous system (n = 37), n ... | 2011 | 3137038 |
| alternating non-cross-resistant chemotherapy for metastatic hormone-independent breast cancer. | a phase ii clinical trial was designed to apply the treatment strategy of alternating non-cross-resistant chemotherapy regimens to patients with metastatic estrogen-receptor negative or hormone-refractory breast cancer. twenty-six patients received adriamycin and cyclophosphamide alternating at 3-week intervals with the combination of vinblastine, mitomycin-c, and 5-fluorouracil (5-fu). toxicity was moderately severe. two patients developed grade 2 and three developed grade 1 stomatitis. a singl ... | 2011 | 3136644 |
| [blood glucose in the acute phase of myocardial infarction treated with nitroglycerin or heparin]. | 2011 | 3136514 | |
| "in situ" modulation of murine neuroblastoma growth and biochemical differentiation by the adrenergic nervous system and nerve growth factor. | 2011 | 3136459 | |
| platelet-activating factor and the cardiovascular system: involvement in cardiac anaphylaxis. | 1988 | 3136455 | |
| determining the prevalence of epilepsy in the semi-urban population of nakuru, kenya, comparing two independent methods not apparently used before in epilepsy studies. | due to meagre resources in terms of trained medical personnel and financial support and the absence of accurate population-based data in most parts of the developing world, there is an urgent need to develop new epidemiological study designs that are simple, accurate and easy to use. key informant methodology and random cluster sample survey methods were used independently (a) to determine the prevalence of epilepsy and (b) to compare the efficiency, cost effectiveness and feasibility of the two ... | 2011 | 3136404 |
| [postoperative debasement of the host-defense system and wound healing in elderly patients, and nutritional support as a therapeutic implication]. | plasma opsonic activity and several kinds of plasma protein levels in each pre- and post-operative days were compared between older 25 cases (70 years or older) and 31 younger cases (59 years or younger) which both underwent elective abdominal surgery. the activity to opsonize e. coli 075 as a host-defense capacity was reduced on postoperative days 1,3 and returned gradually in either young or elderly. but opsonic activity levels in elderly patients in each postoperative days were significantly ... | 1988 | 3136311 |
| hiv seroprevalence in migrant and seasonal farmworkers--north carolina, 1987. | 1988 | 3136308 | |
| segregation analysis of juvenile myoclonic epilepsy. | we examined the inheritance of juvenile myoclonic epilepsy (jme). we looked at both the trait of "epilepsy" and the trait of "epilepsy-plus-eeg abnormalities," since eeg abnormalities are frequently found in the clinically unaffected sibs of jme patients. we tested several modes of inheritance including the fully penetrant recessive and several two-locus models. we could reject all models tested (fully penetrant single-locus and two-locus models) when abnormal eegs were classified as "unaffected ... | 2010 | 3136050 |
| [testicular histology in azoospermia--diagnostic value of plasma fsh, lh, testosterone and prolactin values]. | 2010 | 3136043 | |
| peliosis hepatis in a patient with marasmus. | peliosis hepatitis is a rare disorder previously seen in tuberculosis and malignant disorders and now seen with anabolic steroid use or after renal transplantation. we report the first case of peliosis hepatis in a patient with marasmus and no previously reported predisposing condition. of interest, the peliosis hepatis resolved rapidly (over 2-3 wk) as determined by computed tomography scan and the patient presented with a cholestatic enzyme pattern that resolved with development of the lesion. | 2011 | 3135227 |
| pathology of stranded beluga whales (delphinapterus leucas) from the st. lawrence estuary, québec, canada. | from june 1983 to may 1986, thirteen carcasses of stranded beluga whales from a polluted area of the st. lawrence river, canada were necropsied. high performance liquid chromatography was performed on the brains of three other animals to determine concentrations of benzo a pyrene (bap). two juvenile animals had severe multisystemic lesions one of which, a severe necrotizing dermatitis, was associated with a herpesvirus-like particle. four adults had five varieties of tumours. an adult had a syst ... | 1988 | 3134469 |
| treatment of multiple sclerosis with various interferons: the cons. | while alpha and beta interferons are relatively nontoxic human gene products and have been used in the treatment of multiple sclerosis, the results of a pilot study in 18 patients treated with recombinant gamma interferon indicate that this form is unsuitable for therapy in ms. | 1988 | 3133576 |
| mitomycin-induced prophage induction in vibrio cholerae cells. | 1987 | 3133305 | |
| biosynthesis of porphyrins and left ventricle function in patients with terminal renal insufficiency. | 2011 | 3133291 | |
| the role of percutaneous endoscopic gastrostomy in enteral feeding. guidelines for clinical application. | 2011 | 3133279 | |
| [the overwhelmed intestine syndrome]. | we studied 54 patients who, after small intestinal resection, developed a massive protracted diarrhea with a daily fecal loss greater than 2 kg, status we defined as the "overwhelmed intestine syndrome" (ois). median length of residual small bowel was 120 cm, 19 patients had a definitive stoma (jejunostomy, n = 9; colostomy, n = 10), 26 patients had a provisional jejunostomy. fecal weight greater than 2 kg was related to enteral hyperalimentation (greater than 3,500 kcal) in 19 patients (induced ... | 2011 | 3133276 |
| framework of a protocol for the evaluation of prenatal screening procedures: economic aspects. | 2011 | 3133257 | |
| selective terminal alpha 2-3 and alpha 2-6 sialylation of glycosphingolipids with lacto-series type 1 and 2 chains in human meconium. | human meconium was found to contain two kinds of gangliosides with the same carbohydrate sequence belonging to the lacto-series. they were detected by tlc-immunostaining with monoclonal antibodies directed to the neuac alpha 2-6gal and lc4cer structures. one of these two gangliosides, a major one, which migrated on tlc to a position below that of standard iv3neuacnlc4cer from human erythrocytes, reacted with the antibody to neuac alpha 2-6gal. the other minor one, which migrated on tlc to a posi ... | 1988 | 3133241 |
| theoretical and practical considerations in the doubly-labelled water (2h2(18)o) method for the measurement of carbon dioxide production rate in man. | in the doubly-labelled water (2h2(18)o) method for the measurement of carbon dioxide production rate in man, single exponential disappearance curves for 2h2o and h2(18)o in body water are used; the precision with which the slopes and intercepts of the curves are estimated determines the precision of the estimate of carbon dioxide production rate. in studies with infants, and in computer simulations, the effect of different experimental regimes on the overall precision of the carbon dioxide produ ... | 1988 | 3133206 |
| all-trans retinoic acid with or without low dose cytosine arabinoside in acute promyelocytic leukemia. report of 6 cases. | 2011 | 3133168 | |
| current trends in enteral feeding. | 2011 | 3133160 | |
| inhibition of 7,12-dimethylbenz[a]anthracene-induced genotoxicity in chinese hamster ovary cells by retinol and retinoic acid. | the effects of retinol and retinoic acid on cytotoxicity and mutation expression at the hypoxanthine-guanine phosphoribosyl transferase (hgprt) locus in chinese hamster ovary (cho) cells with or without exogenous metabolic activation were studied in the presence and absence of known chemical mutagens. neither retinol nor retinoic acid induced mutants at the hgprt locus of cho cells at concentrations ranging from 1 microm to 50 microm without exogenous metabolic activation, and at concentrations ... | 1988 | 3133130 |
| risk of upper respiratory tract infection and malaria prophylaxis. | 2011 | 3133070 | |
| drug addicts and the gp. | 2011 | 3133066 | |
| hospital visiting hours: time for improvement. | in a survey of hospital visiting hours in general medical and surgical wards throughout the united kingdom a pattern of visiting emerged showing that many hospitals still have very restricted visiting. a quarter of the 404 hospitals that responded permitted visiting for an average of two hours a day or less. in contrast, just over a third of hospitals allowed visiting for more than five hours a day. there was no relation between visiting times and type of hospital, but a striking regional variat ... | 2011 | 3133059 |
| departmental divisions and the crisis in undergraduate medical education. | 2011 | 3133048 | |
| surgical aspects of drug smuggling. | 2011 | 3133033 | |
| ethics of fetal brain cell transplants. | 2011 | 3133017 | |
| total parenteral nutrition for the treatment of severe hyperemesis gravidarum: maternal nutritional effects and fetal outcome. | hyperemesis gravidarum is a complication of pregnancy that can lead to severe maternal nutritional deprivation. total parenteral nutrition has been used in pregnancy complicated by hyperemesis gravidarum. however, little has been done to study the nutritional aspects of hyperemesis or the maternal effects of total parenteral nutrition when given during the first trimester of pregnancy. the purpose of this study was to examine the nutritional state of pregnancy complicated by hyperemesis gravidar ... | 2011 | 3132667 |
| grand mal seizure after extradural morphine analgesia. | following an elective caesarean section under extradural anaesthesia, a 30-yr-old known epileptic woman (gravida 4, para 3) developed a tonic-clonic seizure, 6 h after the administration of morphine 3 mg into the extradural space. possible aetiological factors are discussed. | 2011 | 3132194 |
| evaluation of the polychlorobiphenyl aroclor 1254 in an animal model of atherosclerosis. | 2010 | 3132110 | |
| [control of growth hormone release by growth hormone-releasing factor and prostaglandin e2 in a system of perfused rat anterior pituitary cells]. | using superfused rat pituitary cells we showed that the growth hormone-releasing factor (grf) and prostaglandin e2 (pge2) increased growth hormone (gh) secretion in a similar manner in terms of kinetics and amplitude of responses. moreover, our data suggest that they stimulate gh secretion mainly by camp-dependent mechanisms. | 1988 | 3131855 |
| class switching from gamma 3 to gamma 2b in a murine pre-b cell line. | class switching from gamma 3 to gamma 2b production at pre-b cell stage was observed in an abelson virus-transformed murine immature cell line that is able to perform vh to djh recombinations followed by class switch recombinations. a series of southern blotting experiments indicates that the class switching from gamma 3 to gamma 2b was mediated by the deletion mechanism of the intervening ch genes on the expressed chromosome and that the break points in the switch recombinations might be differ ... | 1988 | 3131665 |
| imported human rabies--australia, 1987. | 1988 | 3131653 | |
| valproate-associated hepatotoxicity and its biochemical mechanisms. | intake of the anticonvulsant drug valproic acid, or its sodium salt, has been associated with occasional instances of severe and sometimes fatal hepatotoxicity. probably at least 80 cases have occurred worldwide. the syndrome affects perhaps 1 in 10,000 persons taking the drug, and usually develops in the early weeks or months of therapy. most instances have involved children, usually those receiving more than 1 anticonvulsant. multiple cases have occurred in 2 families. the typical presentation ... | 2011 | 3131628 |
| journal reports--a unit event. | 2011 | 3131395 | |
| kinetic analysis of the ca2+-dependent, membrane-bound, macrophage phospholipase a2 and the effects of arachidonic acid. | the kinetics of the ca2+-dependent, alkaline ph optimum, membrane-bound phospholipase a2 from the p388d1 macrophage-like cell line were studied using various phosphatidylcholine (pc) and phosphatidylethanolamine (pe) substrates. this enzyme exhibits "surface dilution kinetics" toward pc in triton x-100 mixed micelles, and the "dual phospholipid model" was found to adequately describe its kinetic behavior. with substrate in the form of sonicated vesicles, the dual phospholipid model should give r ... | 2011 | 3131322 |
| preliminary observations on alterations in prolactin, gonadotropins, e2-17b & progesterone in patients with breast cancer. | 2011 | 3131240 |