Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| structure of a ganglioside with cad blood group antigen activity. | the cad antigen is a rare erythrocyte blood group antigen expressed on both sialoglycoprotein and ganglioside structures. it is related both serologically and biochemically to the sda blood group antigen expressed on over 90% of caucasian erythrocytes. we reported previously that cad erythrocytes contain a novel ganglioside that binds helix pomatia lectin and inhibits human anti-sda antibody. we have now purified the cad ganglioside and determined its structure. the ganglioside contained glc-gal ... | 1988 | 3167001 |
| interaction of n-acetyl-4-epi-d-neuraminic acid with key enzymes of sialic acid metabolism. | in spite of the axially orientated hydroxy group at c-4, the benzyl alpha-glycoside of n-acetyl-4-epi-d-neuraminic acid (4-epi-neuac) is a substrate for sialidases from vibrio cholerae, clostridium perfringens, and arthrobacter ureafaciens, although to an extent which differs depending on the enzyme. surprisingly, v. cholerae sialidase is by far the slowest acting enzyme; this is in contrast to its usual behavior. fowl plague virus sialidase and bovine testis sialidase also cleave this glycoside ... | 1988 | 3166979 |
| chondrogenesis and osteogenesis of bone marrow-derived cells by bone-inductive factor. | rat bone marrow cells were intraperitoneally implanted within a diffusion chamber with a decalcified bone matrix or a 4 m guanidine hydrochloride extracted matrix (g-res) as control. the chamber was harvested after 28 days and soft x-ray photography, histological examination, determination of alkaline phosphatase activity and calcium content were performed. with the decalcified bone matrix, cartilage and bone formation was observed and both alkaline phosphatase activity and calcium content were ... | 1988 | 3166833 |
| [improvement in the academic process preceding vocational practice]. | 2011 | 3166260 | |
| [cavity lining for composite restorations: critical estimate]. | 2011 | 3166150 | |
| compulsory continuing dental education. | 2011 | 3166118 | |
| pediatric orthodontic treatment. | 2011 | 3166014 | |
| [effects of intraligamentous anesthesia on tooth mobility]. | 2011 | 3165813 | |
| [comparative long-term studies on ketac fil and amalgam in deciduous teeth]. | 2011 | 3165808 | |
| ring chromosome 6 and i(17q-) in a patient with acute promyelocytic leukemia. absence of translocation t(15;17). | 1988 | 3165701 | |
| an interstitial deletion of chromosome 7 may characterize a subgroup of uterine leiomyoma. | 1988 | 3165693 | |
| third molar eruption in a 12-year-old girl. | 2011 | 3165662 | |
| an unusual ventilator valve failure. | 2011 | 3165607 | |
| primary prevention of stroke. | 2011 | 3165581 | |
| [guidelines for the management of patients infected by the human immunodeficiency virus]. | 1988 | 3165542 | |
| [low doses of subcutaneous cytosine arabinoside in the treatment of patients with myelodysplastic syndromes]. | 2011 | 3165541 | |
| atypical mycobacterial infections of hickman catheter exit sites. | 1988 | 3165525 | |
| hematologic status in recurrent aphthous stomatitis compared with other oral disease. | the hematologic status of 144 consecutive patients in the united kingdom with oral disease (69 with recurrent aphthous stomatitis; 75 with other disorders) was examined in an attempt to resolve the controversy as to whether levels of hemoglobin, blood cell numbers and indices, and blood film are adequate in the screening of patients with aphthae. though hemoglobin levels and red blood cell indices were normal in patients with recurrent aphthous stomatitis, there was still a small minority of pat ... | 2011 | 3165514 |
| abstracts of the eleventh annual meeting of the japan neuroscience society. tokyo, japan, december 10-11, 1987. | 2011 | 3165498 | |
| yeast activators stimulate plant gene expression. | gal4 is a transcriptional activator found in yeast. two distinct functions of the protein are required for its activity: one directs sequence-specific dna binding, and another interacts with some other component of the transcriptional machinery, for example, rna polymerase ii or a tata-binding protein. two short regions of gal4 function as 'activating sequences' when attached to the dna-binding portion of gal4 and these regions can be replaced by a large number of peptides encoded by escherichia ... | 1988 | 3165494 |
| assessment of c-myc expression in individual leukemic cells. | the expression of the proto-oncogene c-myc was studied at the protein level in cells obtained from patients with aml and cml. in florid aml and during the blastic phase of cml the majority of cells contain c-myc protein with the amount of protein differing widely among the cells of individual patients. in contrast, during complete remission in aml and during the chronic phase of cml cells containing c-myc protein are rare. several studies demonstrated a discordance in the amount of c-myc transcr ... | 2011 | 3165487 |
| [an immunocytochemical study on the prostaglandin e2 localization in human gastric mucosa]. | 1988 | 3165480 | |
| cleavage lines of the oral mucosa in japanese cadavers. | cleavage lines were experimentally reproduced in the oral mucosa of japanese cadavers. they were investigated macroscopically and histologically. the reproduced cleavage lines showed little directional variation by sex or age. from the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria. | 2011 | 3165386 |
| failure to find htlv i and hiv i serum antibodies in ms patients. | 1988 | 3165371 | |
| an investigation into the relative sealing ability of five commercially used temporary restorative materials. | 2011 | 3165335 | |
| interferon alpha-2b as therapy for ph'-positive chronic myelogenous leukemia: a study of 82 patients treated with intermittent or daily administration. | the authors treated a total of 82 patients with ph'-positive chronic myelogenous leukemia (cml) with recombinant interferon alpha-2b (ifn alpha-2b). sixty-five patients in chronic phase (cp), 28 of whom were untreated and 37 pretreated, and nine patients in accelerated phase (ap), were started on ifn three times a week. patients in cp were randomized to receive 2 or 5 x 10(6) iu/m2, while patients in ap were all given the dose of 5 x 10(6) iu/m2, in addition to concomitant chemotherapy. patients ... | 2011 | 3165298 |
| structural and functional studies of the effects of sympathetic nerve stimulation on rabbit submandibular salivary glands. | continuous sympathetic stimulation at 8-10 hz caused intense vasoconstriction in the gland, so stimulation was generally given in an interrupted pattern to minimize this detrimental effect on secretion. only a small increase in fluid secretion occurred; it became thick and tended to block the cannula; therefore in later experiments the main duct was not cannulated. after sympathetic stimulation there was substantial degranulation of acinar cells. however, as this was accompanied by little moveme ... | 1988 | 3165262 |
| [comparative study of physico-chemical and biological properties of human somatotropin produced by genetic engineering and isolated from the pituitary gland]. | human somatotropin hormono (sth), produced by means of gene engineering in the complex program "human growth hormone", managed by the academy of sciences of the ussr, ministry of medical and biological industry of the ussr and ministry of public health of the ussr, was shown to be similar in its physico-chemical properties to the main isoform of highly purified sth, isolated from human hypophysis. as distinct from the hypophyseal sth (sthhyp) containing minor isoforms of the hormone, the prepara ... | 1988 | 3165230 |
| surface charge of macrophages and their interaction with charged particles. | the distribution and concentration of surface ionogenic groups on murine peritoneal macrophages and the responses of their plasmalemma to charged markers were investigated by electron microscopy. quantitation of the distribution of cationized ferritin (cf) as a marker for anionic groups on fixed cells revealed surface anions on invaginated parts of the plasmalemma to be fewer than those on flat or projecting segments. cationic groups on the surface membrane, however, could not be labeled with an ... | 2011 | 3164749 |
| the electronic detection of demineralisation in occlusal fissures. | 2011 | 3164192 | |
| induction of differentiation of human promyelocytic leukemia cells (hl60) by metabolites of hexamethylene bisacetamide. | we studied the ability of five metabolites of hexamethylene bisacetamide (hmba), which we had previously identified in patient urine, to induce differentiation or to influence differentiation induced by hmba of a human promyelocytic cell line. differentiation of hl60 cells was quantified by morphological changes and by the ability to reduce nitroblue tetrazolium. n-acetyl-1,6-diaminohexane (nadah), the deacetylated, first metabolite of hmba, was a more potent inducer of hl60 differentiation than ... | 1988 | 3163938 |
| restoring facial appearance using osseointegrated dental (branemark) implants. | 2011 | 3163066 | |
| temporomandibular disorders. part iii: occlusal and articular factors associated with muscle tenderness. | two complete classes of freshman dental and dental hygiene students, 120 men and 102 women (mean age 23.9 years), were assessed for the presence of masticatory pain or dysfunction by questionnaire, clinical examination, and evaluation of dental casts. the purpose of these examinations was to determine potential relationships between clinical muscle tenderness, occlusal relationships, and signs of tmj dysfunction. awareness of muscle tenderness increased with the number of muscle sites involved ( ... | 2011 | 3162994 |
| retreatodontics and ultrasonics. | 2011 | 3162934 | |
| racial differences in acute lymphocytic leukemia mortality and incidence trends. | mortality and morbidity rates for childhood leukemia are examined with reference to time trends and racial differences. prior to 1964, white and nonwhite children had very different acute lymphocytic leukemia (all) mortality rates. with the advent of successful chemotherapy, the mortality rate of all in white children has decreased resulting in virtually no racial differences in all mortality. the reasons for a stable all mortality rate in nonwhite children despite successful chemotherapy includ ... | 2011 | 3162512 |
| cancer control in rhode island: part ii. the roger williams cancer screening program. | 2011 | 3162329 | |
| the fate of memory: comment on mccloskey and zaragoza. | mccloskey and zaragoza (1985) argue that misleading postevent suggestions do not affect the availability of originally encoded information. their hypothesis stems from empirical work using a modified paradigm in which no effect of postevent information is observed. although their "no impairment" hypothesis is plausible, careful consideration of the predictions of their experimental test suggests that it may be insufficiently sensitive to reveal the impact of postevent information. a small effect ... | 2011 | 3161981 |
| a computational analysis of mental image generation: evidence from functional dissociations in split-brain patients. | recent efforts to build computer simulation models of mental imagery have suggested that imagery is not a unitary phenomenon. rather, such efforts have led to a modular analysis of the image-generation process, with separate modules that can activate visual memories, inspect parts of imaged patterns, and arrange separate parts into a composite image. this idea was supported by the finding of functional dissociations between the kinds of imagery tasks that could be performed in the left and right ... | 2011 | 3161979 |
| does treatment timing matter?--a double blind crossover study of ibuprofen 2400 mg per day in different dosage schedules in treatment of chronic low back pain. | 2011 | 3161532 | |
| the relations between erythrocytic and cns parameters following postnatal hypobaric hypoxia of the rat. | in the present paper the relations between selected erythrocytic criteria and alterations of biochemical brain parameters following hypoxia were investigated in order to find out the relevance of erythrocytic criteria for the diagnosis of hypoxia-induced alterations of the cns during development. newborn wistar rats (n = 80) with their mother were exposed to hypobaric hypoxia, po2 = 11.3 kpa, from day 2-10 of life, daily for 11 h. on the 11th day of life the animals had a lower body (38%), liver ... | 1985 | 3161100 |
| occupational skin disease. | 2011 | 3161016 | |
| [percutaneous transluminal angioplasty, using the "kissing" technic, in infrarenal aortic stenosis]. | 2011 | 3160999 | |
| direct selection of mutations reducing transcription or translation of the reca gene of escherichia coli with a reca-lacz protein fusion. | when a reca-lacz protein fusion was cloned into phage lambda, the resulting transducing phage grew normally on wild-type escherichia coli, but its growth was severely inhibited in lexa(def) mutant strains that express reca constitutively at high levels. mutants of the transducing phage that grew on the lexa(def) strains were isolated and were found to affect production of the reca-beta-galactosidase hybrid protein. most mutants, including a number of nonsense mutants, were phenotypically lacz-. ... | 1985 | 3160689 |
| alcoholism and skin disease. | one hundred and one patients who met criteria for alcoholism were evaluated for dermatologic signs. there were 98 men and 3 women, with an average age of 40.85 years; 40 were white and 61 black. significant findings were no skin disease in 19, acne in 27, folliculitis in 8, seborrheic dermatitis in 12, tinea pedis in 32, and xerosis in 7. only two patients had rosacea, which is contrary to previously held beliefs about the drinker's nose. | 2011 | 3160677 |
| bonding of restorative materials to dentine. | the potential advantages of bonding a filling material to dentine have long been recognized by the dental profession. such bonding would prevent recurrent decay and would provide a long-lasting restoration. bonding of suitable filling materials to enamel can be easily accomplished by first etching the enamel with acid. this opens up areas in the enamel and permits filling materials to flow into the openings and form mechanical locks. it is not possible to do this with dentine since the acid used ... | 2011 | 3160665 |
| [comparison of immunogenic and reactogenic properties of various types of vaccinating substances against rubella]. | 2010 | 3160492 | |
| renal apical membrane cholesterol and fluidity in regulation of phosphate transport. | renal proximal tubule cells adapt to dietary phosphate (pi) restriction by increasing pi transport independent of parathyroid hormone, vitamin d metabolites, or serum ca2+. to determine the underlying cellular mechanism(s), brush border (bbm) and basolateral membranes (blm) were isolated from growing male rats fed a synthetic diet containing variable levels of pi (0.1-1.4%). dietary pi restriction was without effect on either bbm or blm total lipid phosphorus, individual phospholipid species, or ... | 1985 | 3160247 |
| the use of dura mater allograft in the surgical repair of large defects of the abdominal wall. | the dura mater allograft is being used as an abdominal fascia substitute and major advantages are documented. it was used successfully in four patients at this institution, with a ten month follow-up period. its strength, durability, tissue tolerance, flexibility, ease of handling, nonallergenic property, availability and stability in the presence of infection make it a good graft to be used in the repair of large abdominal hernias. we are quite convinced that long term follow-up results will ve ... | 2010 | 3160130 |
| the use of dura mater allograft in the surgical repair of large defects of the abdominal wall. | the dura mater allograft is being used as an abdominal fascia substitute and major advantages are documented. it was used successfully in four patients at this institution, with a ten month follow-up period. its strength, durability, tissue tolerance, flexibility, ease of handling, nonallergenic property, availability and stability in the presence of infection make it a good graft to be used in the repair of large abdominal hernias. we are quite convinced that long term follow-up results will ve ... | 2010 | 3160130 |
| monoclonal antibodies to outer membrane antigens of vibrio cholerae. | hybridoma-derived monoclonal antibodies were prepared against outer membrane antigens of four strains of vibrio cholerae that were cultivated under iron-limited conditions, and these antibodies were partially characterized. we established a library of 66 hybridomas which produced monoclonal antibodies defining 16 different v. cholerae antigens. two antigens (molecular weights, 18,000 and 112,000) were heat modifiable, whereas the reacting epitope of a third antigen (40,000-dalton-18,000-dalton d ... | 1985 | 3159676 |
| short term effect of medroxyprogesterone acetate on the rat intestinal digestive & absorptive functions. | 1985 | 3159660 | |
| calla-positive myeloma: an aggressive subtype with poor survival. | detailed immunotyping was carried out on 21 direct myeloma bone marrow aspirates and eight human myeloma cell lines. four previously untreated common acute lymphoblastic leukemia antigen (calla)-positive myeloma patients were identified and six of eight cell lines (75%) were also positive. calla positivity, as part of an immature b phenotype, was found to correlate with very aggressive clinical disease: median survival six months v 56 months for the calla-negative group. | 1985 | 3159443 |
| fixed eruptions: causative drugs and challenge tests. | the drugs responsible for eighty-six cases of fixed drug eruption have been identified, and in all but two were confirmed by challenge. the series included sixteen cases of generalized bullous fixed eruption, which resembles lyell's syndrome. the main causative drugs were phenazones and barbiturates, both in the series as a whole and in the group of the most severe cases. the same drugs were the most frequent causative agents in a report from finland 10 years ago. | 2011 | 3159412 |
| clinical experience with a new formulation of midazolam--10mgs in 5ml solution. | 2011 | 3159107 | |
| the composition of the ceramides from human stratum corneum and from comedones. | human epidermal surface lipids were collected by an ethanol wash and the ceramides were quantified by thin-layer chromatography-photodensitometry. six ceramide fractions were isolated and the structural components of each were analyzed in detail. the most unusual of the epidermal ceramides contained a sphingosine base with amide-linked 30- and 32-carbon omega-hydroxyacids and an ester-linked nonhydroxyacid, 41% of which was linoleic acid. the proportion of linoleic acid in the analogous ceramide ... | 1985 | 3158712 |
| industrial back pain in europe. | 2011 | 3158513 | |
| sensory reinnervation of cat peroneus brevis muscle spindles after nerve crush. | results are presented of examining the postcrush sensory reinnervation of cat peroneus brevis muscle spindles previously investigated physiologically by hyde and scott. it is shown that primary and secondary endings were successfully restored in their final form in the early stages of recovery. the primary endings were shorter than normal and had fewer transverse bands; 12% were judged to be hyperinnervated. some secondary endings showed signs of growth through the primary region apparently desi ... | 1985 | 3158372 |
| [hepatitis b immunization--when is a booster injection necessary?]. | over 10,000 high risk individuals in the zurich area have been vaccinated against hepatitis b with 3 initial injections of 20 micrograms h-b-vax. the question arises whether, and if so when, booster injections should be given. concentrations and persistence of the protective anti-hbs antibodies of 158 successfully vaccinated individuals (medical staff, patients on hemodialysis or with renal transplants) were analyzed. the anti-hbs behaved typically in most individuals, reaching maximum levels in ... | 2011 | 3158072 |
| [polyradiculoneuritis in a heroin addict]. | 2011 | 3157840 | |
| glucose 1,6-bisphosphate decline in human erythrocytes: possible involvement of phosphoglucomutase pgm2 isoenzymes. | human erythrocytes incubated with various sugars lower their glucose 1,6-bisphosphate (glc-1,6-p2) content, as do haemolysates containing exogenous glc-1,6-p2 incubated with sugar monophosphates (sugar-p). experiments performed with isolated erythrocyte phosphoglucomutase (pgm) isoenzymes indicate that only definite isoenzymatic forms, namely pgm2, are able to consume glc-1,6-p2 during the mutation of sugar-p other than glucose-p. in this process a phosphate group is released from glc-1,6-p2 and ... | 1985 | 3157431 |
| the dexamethasone suppression test and depressive signs in dementia. | the non-suppression by dexamethasone of endogenous cortisol production has been held to be a specific and sensitive indicator of biological depression. non-suppression has, however, been reported in a proportion of patients with severe dementia. in the present study failure of suppression was found in 10 out of 20 demented patients. the non-suppressors scored significantly higher on a scale of signs of depression. following antidepressant treatment, 3 out of 8 non-suppressors reverted to normal ... | 2011 | 3156915 |
| the changing institutions. | 2011 | 3156425 | |
| increased sce inducibility by low doses of methylcholanthrene in lymphocytes obtained from patients with down's disease. | the inducibility of sister-chromatid exchanges (sces) following 3-methylcholanthrene (mc) treatment of normal human peripheral blood lymphocytes and of in vitro cultured normal human embryo fibroblasts, as well as peripheral blood lymphocytes of patients with down's disease and of fibroblasts of an embryo with trisomy 21 has been investigated. 10(-6) m mc treatment increased the frequency of sces by 2.5 in the case of down lymphocytes when compared to the healthy control. the fibroblasts with tr ... | 1985 | 3156274 |
| comparison of quantitative and visual detection of new focal bone lesions. | a comparison is made between the sensitivity of detection of focal abnormalities in radionuclide bone images by visual examination and by using simple quantification. the quantitative method calculates the ratio of radiopharmaceutical uptake in a region of interest drawn around a lesion to that in an area of normal bone. quantification is found to be far more sensitive than visual examination in detecting focal metastases. the use of "baseline" images improved the precision of quantitation of ri ... | 2011 | 3156219 |
| preliminary characterization of a soluble immunosuppressive molecule from dba/2 spleen cells using monoclonal antibody immunoadsorbence. | in a previous publication a monoclonal antibody (b16g) which appeared to recognize t suppressor cells and a t-suppressor factor (tsf) in the spleens of dba/2 mice was described. b16g appears to be directed to a public specificity of dba/2 tsf and therefore has been shown to inhibit a variety of immunological reactions. the present study involves preliminary characterization of the material with which b16g reacts. it was found that the b16g-reactive protein (putative tsf) could be absorbed and el ... | 2011 | 3155655 |
| influenza viruses as lymphocyte mitogens. i. b cell mitogenesis by influenza a viruses of the h2 and h6 subtypes is controlled by the i-e/c subregion of the major histocompatibility complex. | influenza a viruses of the h2, h3, and h6 subtypes function as t cell-independent b cell mitogens for lymphocytes from balb/c mice. lymphocytes from c57bl/10 mice, however, undergo mitogenesis only in response to h3 viruses. the failure of c57bl/10 lymphocytes to respond to h2 and h6 viruses was shown not to reflect a difference in dose-response profile or kinetics of the response, nor was it due to the activity of suppressor t cells. experiments with congenic and recombinant strains of mice est ... | 1985 | 3155540 |
| surgical management of palatally impacted cuspids. | 2011 | 3155369 | |
| the biochemistry of endogenous organosulphur compounds. | the role and metabolism of methionine and cysteine in mammals are described. an outline of the history of glutathione, of its function in maintaining the thiol status of the cell and of its protective action against oxidative stress, is given. the importance of glutathione reductase, glutathione peroxidases, glutathione-s-transferases in endogenous metabolism and of gamma-glutamyltranspeptidase is described. the relationship between cysteine and glutathione is considered together with the inter- ... | 2011 | 3155361 |
| immunobiological relationships between vibrio fluvialis and vibrio cholerae enterotoxins. | a total of 26 strains of vibrio fluvialis was included in this study, which were isolated from patients with diarrhoea and other sources. the gm1 enzyme linked immunosorbent assays performed with the culture filtrates of v. fluvialis yielded negative results, indicating that their receptor site is different from that of the known labile toxin. the cholera antitoxin failed to neutralize the skin permeability factor activities of all the v. fluvialis culture filtrates and none of the concentrated ... | 1988 | 3155161 |
| prospective evaluation of risk factors in retinal re-detachment. | 2011 | 3155086 | |
| effect of hla matching and cyclosporine a in renal transplantation. anzdata registry. | 1. graft survival rates increased significantly in primary and second cadaver transplants as well as in one-haplotype matched living related donor renal allografts treated with csa. 2. hla mismatching did not seem to influence survival of primary cadaver grafts in transfused recipients. 3. no pertinent analysis was available owing to the small size of the group of nontransfused patients. 4. hla mismatching did not appear to influence survival of second cadaver grafts in csa-treated patients; the ... | 2009 | 3154456 |
| center effect. | 1. the center effect persists through the period studied--transplants performed in 1983 and 1984. consistent differences remain in outcome as measured by one-year graft survival. after discounting statistical variation, the extreme difference is approximately 40-50% for first grafts from cadaver donors. 2. the magnitude of the differences remains when cyclosporine is used. 3. centers differ with respect to factors generally considered related to graft outcome, but the differences account at most ... | 2009 | 3154395 |
| [multiple ocular localization of a chronic atrophic polychondritis]. | 2011 | 3153875 | |
| aids as a neuropeptide disorder: peptide t, vip, and the hiv receptor. | 1988 | 3153485 | |
| continuous arteriovenous hemofiltration in children. | continuous arteriovenous hemofiltration (cavh) is an extracorporeal technique for the treatment of hypervolemia and electrolyte disturbances in the critically ill patient with oligoanuria. the patient's cardiac output provides the blood flow through the circuit; no pumps are necessary. a range of hemofilters is now available extending the applicability of cavh to the pediatric population, including premature newborns. in this report the treatment of 15 neonates and 8 older children is described. ... | 2010 | 3153297 |
| renal growth after neonatal urinary tract infection. | this study presents the result of 12-21 years' follow-up in a group of children with neonatal urinary tract infection (onset within 1 month after birth) in whom early renal growth retardation was noted without concomitant classical renal scarring. in all cases the neonatal infection was diagnosed and treated within a few days of onset and the patients were closely supervised thereafter. renal length, parenchymal thickness and area were measured at urography. at first follow-up (22 children, mean ... | 2010 | 3153287 |
| recent advances and controversies in childhood renal osteodystrophy. | renal osteodystrophy starts very early in chronic renal failure. although vitamin d levels are normal in patients with 70-80% function, the levels are not appropriate to the prevailing biochemical milieu. renal osteodystrophy may contribute to renal growth failure but a correlation between the degree of renal osteodystrophy and growth failure is not observed. catch-up growth cannot be obtained over a longer period of time with vitamin d. the main reason for osteomalacia is al intoxication. alumi ... | 2010 | 3153280 |
| low-renin hypertension of childhood. | measurement of plasma renin activity (pra) and aldosterone with a knowledge of dietary sodium balance is critical to the diagnostic evaluation of childhood hypertension. disturbances of steroid production, regulation, metabolism and sensitivity have been implicated in the pathogenesis of low-renin hypertension in childhood. prompt initiation of treatment is essential because the hemodynamic changes caused by long-standing hypertension may become irreversible. the clinical features and hormonal f ... | 2010 | 3153266 |
| heredity and blood pressure in humans: an overview. | this paper presents a review of the genetic transmission of normal blood pressure and of essential hypertension. familial aggregation of normal blood pressure has been reported in adults, in children and even in newborns. blood pressure aggregation phenomenon, however, is the result of both a genetic component and shared environmental factors. more specific for each etiological factor were the studies of blood pressure aggregation in twins and in adopted children. attention was focused on the mo ... | 2010 | 3153263 |
| immunology. | 2010 | 3153253 | |
| acute circulatory effects of doxorubicin in the conscious dog. | experimental work on the mechanisms of acute doxorubicin-induced cardiotoxicity may contribute to a better understanding of the clinical problem of cardiac failure after treatment with anthracycline derivatives. we studied aortic pressure and heart rate continuously for 1 h following a bolus injection of doxorubicin (1 mg/kg) in 7 dogs. in contrast with previous studies in intact animals, no anesthesia was used in order to eliminate possible interactions of doxorubicin with other drugs. one minu ... | 1986 | 3153244 |
| acute leukemia with extramedullary presentation and mixed myeloid and lymphoid expression. | 2010 | 3153242 | |
| childhood cancer in siblings. | the medical records of 973 previously untreated patients diagnosed between january 1960 and december 31, 1978 with childhood cancer were reviewed. siblings in 13 families were diagnosed with cancer 9/12 to 15 years after the diagnosis of cancer in the index sibling. previously unreported association of acute lymphoblastic leukemia with hodgkin's disease, neuroblastoma with malignant hemangiopericytoma, non-hodgkin's lymphoma with malignant melanoma, wilms' tumor with non-hodgkin's lymphoma, hodg ... | 2010 | 3153235 |
| neuroblastoma--an overview of laboratory studies aimed at inducing tumor regression by initiation of differentiation or administration of antitumor drugs. | experimental laboratory investigations aimed at inducing tumor regression are reviewed critically. possible interference with tumor growth by induction of differentiation has stimulated studies employing cell lines in vitro and in vivo of murine and, more recently human origin. the diverse range of agents proving effective inducers has facilitated studies of morphological and biochemical differentiation. however, the precise molecular events involved are still unclear, and any therapeutic potent ... | 1986 | 3153219 |
| plasma and erythrocyte concentrations of mercaptopurine after oral administration in children. | plasma and erythrocyte concentrations of 6-mercaptopurine (6-mp) were determined by gas chromatography-mass spectrometry. eleven children (9 with acute lymphatic leukemia) were studied after oral intake of 6-mp doses ranging between 31 and 128 mg/m2 body surface area. the concentrations of 6-mp in plasma were found to vary considerably between patients even after dose normalization to 75 mg/m2. after dose normalization the mean peak plasma concentration was 0.68 microm (range 0.12-1.38) and the ... | 2010 | 3153216 |
| [bilirubin and bile acids: 2 prognostic factors in biliary atresia]. | 2010 | 3153206 | |
| [treatment of essential vesico-ureteral reflux in children: computer-assisted decision]. | 2010 | 3153193 | |
| how do bacteria attach to solid surfaces? | 2010 | 3153184 | |
| anti-idiotypic antibodies: a new generation of vaccines against infectious agents. | anti-idiotypic antibodies have been suggested recently as candidates for potential vaccines against numerous infectious organisms. these antibody-based vaccines might represent a new generation of vaccines for inducing protective immunity in susceptible hosts. | 2010 | 3153167 |
| the iridovirus frog virus 3: a model for trans-acting proteins. | the amphibian iridovirus, frog virus 3 (fv3), produces at least two trans-activating proteins that stimulate the expression of viral genes. one of these proteins induces transcription from the promoter of an immediate-early fv3 gene, whereas the other induces transcription from exogenously methylated dna. these proteins may serve as a model for both viral and cellular trans-acting factors. | 1986 | 3153144 |
| effects of growth hormone therapy and malnutrition on the growth of rats with renal failure. | we examined the effects of methionyl-human growth hormone (met-hgh) and malnutrition on the growth of 5/6 nephrectomized rats and sham-operated controls. one group of sham-operated rats (pfs) was pair-fed with a group of nephrectomized rats in renal failure (rf); another group of sham-operated rats was fed ad libitum (als), and a final group of rats with renal failure (rf-gh) was treated with 4 iu/day met-hgh. after 4 weeks, rf-gh rats gained 12.3 +/- 1.7 cm in length; this was more than the 10. ... | 1988 | 3153055 |
| diagnosis and treatment of iron overload in paediatric patients on chronic haemodialysis. | in this study the incidence and contributing factors of iron overload in paediatric patients treated with intermittent haemodialysis were evaluated. particular attention was given to the diagnostic value of serum ferritin in the assessment of body iron stores in patients with hepatocellular damage. the results of treatment of secondary haemosiderosis with desferrioxamine (dfo) are reported. serum ferritin levels were measured in 18 children and adolescents undergoing long-term haemodialysis; 8 o ... | 2011 | 3153030 |
| aspects of brazilian paediatric nephrology. | brazil is a large country with different population densities in its five geographical regions, each of which has severe but unevenly distributed socioeconomic problems which affect the health care system. this makes the accurate assessment of renal disease in the large paediatric population which comprises 40% of the total population especially difficult. this paper analyses the experience of one paediatric nephrology unit. urinary tract infection affecting 44% of the patients was the most comm ... | 2011 | 3153022 |
| successful islet transplantation in bb rats without chronic immunosuppression. | 1987 | 3152652 | |
| vascular dysplasia of arteries in neurocristopathies: a lesson for neurofibromatosis. | in a 15-year-old girl suffering from congenital constipation, megacolon combined with a 'ranken neuroma' of the rectum and a short aganglionic segment of distal colon was observed. the specific vascular alterations in the region of the ranken neuroma (which has previously been described in cases of von recklinghausen neurofibromatosis) were studied, with an emphasis on immunohistochemical methods. the results suggest that the pericytes are the cells primarily involved in the distinctive alterati ... | 2010 | 3152480 |
| [evaluation of two experimental models of end-to-side microvessel anastomosis in rats]. | 1988 | 3151320 | |
| health education for children in the control of schistosomiasis. | health education for children is an important measure in the control of schistosomiasis especially considering the characteristics of the disease during childhood, such as high prevalence, high percent of treatment resistance, high rates of egg elimination and high level of reinfection, as reported in studies conducted in endemic areas. all of these facts indicate that children play a role in the maintenance and transmission of schistosomiasis. historically in brazil, health education concerning ... | 2011 | 3151105 |
| cell-free assays and the mechanism of receptor-mediated endocytosis. | 2011 | 3150882 | |
| therapeutic effect of dexamethasone in t-2 toxicosis. | t-2 toxin is a mycotoxin that induces toxemia characterized by numerous hematological and biochemical changes. we have previously shown that prostaglandin (pg) production in brain tissue is increased following t-2 toxin. the present study was designed in order to test the effect of dexamethasone on brain prostaglandins and survival of rats subjected to t-2 toxin. furthermore, the effect of bw 755c, a dual inhibitor of the cyclooxygenase and lipoxygenase pathways of arachidonate metabolism, on th ... | 1987 | 3150046 |
| pertussis vaccines in japan. | 2010 | 3149848 |