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accuracy of self-reports of acquired immunodeficiency syndrome and acquired immunodeficiency syndrome-related conditions in women.to investigate the validity of self-reported acquired immunodeficiency syndrome (aids) among women enrolled in a prospective study of human immunodeficiency virus (hiv) infection, the authors compared the self-reported occurrence of aids-specific diagnoses with aids diagnoses documented by county aids surveillance registries. also examined was the association between participant characteristics and the validity of self-reports. among the 339 hiv-infected participants in the northern california w ...200111390333
differences in the temporal trends of hiv seroincidence and seroprevalence among sexually transmitted disease clinic patients, 1989-1998: application of the serologic testing algorithm for recent hiv seroconversion.the authors compared temporal trends in the prevalence and incidence of human immunodeficiency virus (hiv) infection based upon 34,866 specimens from patients who attended the san francisco, california, municipal sexually transmitted disease clinic between 1989 and 1998. hiv infection data were collected during annual blinded hiv serologic surveys. incidence was determined by applying a serologic testing algorithm for recent hiv seroconversion that uses both a sensitive and a less sensitive enzy ...200111384946
incidence of hiv among injection drug users entering drug treatment programs in four us cities.we estimated seroincidence of human immunodeficiency virus (hiv) and prevalence of risk behaviors among injection drug users (idus) who accepted voluntary hiv testing on entry to drug treatment. record-based incidence studies were conducted in 12 drug treatment programs in new york city (n = 890); newark, new jersey (n = 521); seattle, washington (n = 1,256); and los angeles, california (n = 733). records of confidential hiv tests were abstracted for information on demographics, drug use, and hi ...200111368194
sex offender targeted.residents from a fresno california neighborhood are protesting outside the home of an hiv-positive rapist released from a state mental hospital. the man, convicted of two rapes, has been hiv positive since 1986 and is not taking any medications, according to various sources. the residents say they plan to protest until he leaves in order to protect their children. however, it is illegal to harass a sex offender based on information the police release.199911367145
stop the abuse of hiv+ women prisoners at chowchilla.a change in the way the central california women's facility (ccwf) in chowchilla distributes hiv medications has sparked a new crisis for its prisoners. before the change, hiv-positive women received a monthly supply of pills, and could dose privately in their cells. now the women must stand outside in a pill call line three times per day, where they are "observed" receiving and taking their medications. because the prison's new medication administration schedule does not correlate to some presc ...199911366855
fighting for their lives: human rights abuses of hiv + incarcerated women.even though the number of hiv-positive individuals in u.s. prisons has grown, federal and state departments of corrections do not have comprehensive hiv treatment or education programs. in march 1999, amnesty international launched a campaign against medical neglect in u.s. women's prisons and jails. the story of an hiv-positive inmate and her struggle to receive the proper care and treatment for her condition are detailed. contact information is provided.199911366854
lawsuit settled.taco bell inc. settled a lawsuit by a california man claiming wrongful discharge because of his hiv infection and sexual orientation. terms were not disclosed, but the suit by the late ray martinez (and continued by his mother) sought $32,000 in back pay. the suit alleged that martinez was fired after his superiors learned his hiv status. the company claimed martinez was not performing his duties.199911366448
bogus test kits.a california man, larry c. greene, was sentenced to 63 months in federal prison after being convicted of marketing phony hiv home test kits. greene's sentence was the maximum allowed. u.s. district judge robert e. coyle said greene showed no remorse for the emotional harm he caused to his customers. greene marketed the kits through the internet and more than 30 local pharmacies. he claimed the kits were "confidential, safe, accurate, and easy to use". the food and drug administration (fda) recal ...199911366389
coburn presses hhs to enforce spousal notification law. department of health and human services.representative tom coburn of oklahoma is demanding that the department of health and human services (hhs) investigate whether states are making good-faith efforts to comply with the spousal notification programs mandated by the ryan white care act amendments. coburn is threatening legal action to compel enforcement of the provision. when congress reauthorized the notification program in 1996, they added language that barred hhs from awarding grants to a state unless it attempted to notify spouse ...199811365953
pharmacy settles suit.a suit was filed by an hiv-positive man against a pharmacy that inadvertently disclosed his hiv status to his ex-wife and children. his ex-wife tried to use the information in a custody battle for their two children. the suit against the pharmacy was settled, but the terms of the settlement remain confidential.199811365933
california revamps policy for aids education in schools.california now requires school districts to notify parents or guardians, and receive their consent, before pupils receive education on hiv or human sexuality. any instruction that is arranged for outside of the curriculum, such as a guest speaker, must be disclosed to parents or guardians for their review, prior to the additional instruction. the curriculum should provide the most current information from federal public health officials, including emphasizing monogamy or avoidance of multiple se ...199811365752
suit alleges pharmacist told man's family about his hiv diagnosis.longs pharmacy is being sued for invasion of privacy, negligent infliction of emotional distress, and violations of state medical disclosure laws by a man whose hiv status was revealed to others. the suit alleges that the pharmacist asked the man's ex-wife if she wanted to pick up his prescriptions, and when she asked what they were for, he told her the prescriptions were for aids. the woman was distraught, and filed papers in family court to limit his custody rights. the action is pending. earl ...199811365095
infected sex partner wins dismissal of assault charges.the california court of appeals ruled that a man who had unprotected intercourse with an underage female without disclosing his positive hiv status cannot be charged with aggravated assault. the court determined that prosecutors did not prove that the risk of hiv transmission from one act of unprotected heterosexual sex fell within california's definition of aggravated assault. the defendant, dennis guevara, will face trial on four counts of unlawful sexual intercourse, one count of failing to r ...199811364962
thorny issues confront california lawmakers in 1998.when the california legislature reconvenes in january 1998 it will consider bills that were not resolved during the 1997 session. senate bill 705 makes it a felony for a person to intentionally infect another person with hiv through sexual activity. the current version of s.b. 705 only punishes those who intend to expose others to hiv through unprotected anal or vaginal intercourse. senate bill 885 would waive california's ban on nonprescription use of syringes and create a government-sanctioned ...199711364783
employer loses bid to force insurer to pay in bias suit.educational testing services (ets) tried to force its insurer, liberty mutual fire insurance company, to reimburse it for money paid to settle a lawsuit brought by frank vincent perrault, a california man fired in 1990. a u.s. district judge ruled that because perrault claimed he was fired due to his hiv status, liberty mutual was not liable. the discriminatory conduct alleged by perrault fell outside the scope of the insurance that ets had purchased. in 1991, shortly after perrault sued, ets ma ...199711364346
life sentence sought.humboldt county (ca) district attorney terry farmer is seeking a life sentence without the possibility of parole for an hiv-positive man. thomas m. fox may be convicted on charges of murder, child abuse, administering drugs to commit a felony, and using minors to produce pornography. an 11-year-old boy was believed to be a victim in fox's child pornography scheme. the boy's body was found dumped on a rural road. police found a cache of pornographic pictures of young boys in fox's apartment.199711364163
man with aids can stay despite minimum-age rule.a woman in california won a lawsuit against the mobile home park association for trying to evict her for having her aids-infected son living with her. the park had waived its residency requirements in the past for other lengthy stays for medical or financial hardships, but refused to do so in this case. federal law prohibits anyone losing their housing due to prejudice against people with disabling conditions.199611364070
calif. mobile home park sued for trying to eject man with aids.the u.s. justice department sued a california mobile home park for refusing to allow a man living with aids to continue living there under his mother's care. the huntington shorecliffs mobile home park refused to waive its residency rules and tried to evict the mother. u.s. attorney nora m. manella alleges that the mobile home park violated the fair housing act by discriminating on the basis of disability.199611363580
court voids $275,000 award because plaintiff died on appeal.the california court of appeals denied the family of a deceased man from pursuing emotional distress damages because the plaintiff died before the appeal process was completed. joseph a. sullivan, a former delta air lines employee, sued the company for a variety of violations, including breach of confidentiality and unlawful discrimination based on his hiv status. a jury awarded sullivan $275,000 in emotional distress damages, but decided in favor of delta on three other counts. delta appealed, ...199611363285
sex education critics get their say at congressional hearings.hearings conducted in december 1995 by the house education and opportunities subcommittee on oversight and investigations included criticism of school-based condom distribution programs and sex education. rep. peter hoekstra (r-mi) led the hearings and stated that witnesses would examine the roles parents and students play in transmitting values to children. the human rights campaign charged that most of the invited witnesses were part of an anti-gay campaign directed by louis sheldon, a califor ...199511362960
wider access to human growth hormone.medical will now provide reimbursement for the recombinant human growth hormone (serostim) from serono laboratories through an food and drug administration (fda)-sanctioned treatment investigational new drug program. the drug has shown promise in the treatment of aids-related wasting. california has appropriated $10 million for serostim for medical clients. patients qualify to receive the drug if they have failed either megace or marinol. patient reimbursement advocacy activities and the distrib ...199511362898
courts uphold hiv test for rapist, but not for child molester.mandatory hiv testing of convicted sex offenders can be ordered by trial judges. in two separate california appeals court cases, the judges reached opposite conclusions regarding this testing. one court upheld the mandatory testing of a man convicted of rape. in another california case, regarding a convicted child molester, the court overturned the order to submit to mandatory testing. the appeals court said that the jury had not provided enough information to determine whether or not testing wa ...199511362743
california: medi-cal can pay for human growth hormone for some patients.medi-cal will pay for human growth hormone through the serono treatment ind starting aug 1, 1995. eligible patients must have aids-related wasting with a loss of at least ten percent of body weight, be eighteen years of age or older, and have failed treatment with either megace or marinol.199511362625
animal cell transplantation: fda meeting july 13 and 14. food and drug administration.advances in organ and cell transplantation, and in basic immunology, are increasing the possibility of transplantation of organs or cells from animals to humans. baboon immune cells are resistant to hiv infection. if the cells can survive transplantation to humans, they might conceivably provide immunological resistance to hiv. shortly before the first test of baboon to human cell transplantation was to occur, the food and drug administration (fda) expanded its authority and told the researchers ...199511362616
congress: how to help.citizen input, through letters, calls, and visits to government representatives, is needed more urgently now than ever before. the fiscal 1996 budget and appropriations process is expected to provide disappointments. the house has eliminated hopwa aids housing funding for the current year (although it could be reversed in the senate). moves are being made toward mandatory hiv testing, with no provisions for counseling or for care. there is no mass movement yet to support aids politically, and th ...199511362405
human vaccine testing set. 199811361942
medi-cal reimburses for growth hormone. 199511361448
lifestyle determinants of 5alpha-reductase metabolites in older african-american, white, and asian-american men.men with higher endogenous 5alpha-reductase activity may have higher prostate cancer risk. this hypothesis raises two questions: (a) could racial differences in 5alpha-reductase activity explain the observed racial differences in prostate cancer risk? and (b) could a man reduce his activity level by modifying his lifestyle? to address these questions, we measured two hormonal indices of 5alpha-reductase activity [serum levels of androstane-3alpha-17beta-diol glucuronide (3alpha-diol g) and andro ...200111352865
an event-by-event probabilistic methodology for assessing the health risks of persistent chemicals in fish: a case study at the palos verdes shelf.a human health risk assessment of recreational anglers who consume fish from the palos verdes shelf was conducted. the uptake of ddt, dde, and ddd (collectively total ddt or tddt) and polychlorinated biphenyls (pcbs) due to fish ingestion was characterized using monte carlo techniques. this analysis relied upon 176 probability density functions developed from over 300,000 individual pieces of information to represent 17 different exposure factors that influence the human uptake of persistent org ...200111339333
detection of arboviral rna directly from mosquito homogenates by reverse-transcription-polymerase chain reaction.many arthropod-borne viruses (arboviruses) are important human pathogens medically. the development of an effective technique to detect the viruses by using nucleic acid amplification, such as polymerase chain reaction (pcr), improves not only clinical diagnosis but also virologic surveillance of mosquito vectors in the field. in this study, the development of an improved and simplified assay is described for detection of mosquitoes infected with eastern equine encephalitis (eee) virus, cache va ...200111337046
targeted testing of children for tuberculosis: validation of a risk assessment questionnaire.given the directive of the american academy of pediatrics to test children for tuberculosis (tb) only if they are at high risk for the disease, we sought to determine how well a risk assessment questionnaire can predict a positive tuberculin skin test (tst) result among children seen in a medical office setting.200111335775
multi-stage model estimates of lung cancer risk from exposure to diesel exhaust, based on a u.s. railroad worker cohort.a california environmental protection agency (cal/epa) report concluded that a reasonable and likely explanation for the increased lung cancer rates in numerous epidemiological studies is a causal association between diesel exhaust exposure and lung cancer. a version of the present analysis, based on a retrospective study of a u.s. railroad worker cohort, provided the cal/epa report with some of its estimates of lung cancer risk associated with diesel exhaust. the individual data for that cohort ...200111332538
costs of occupational injuries and illnesses in california.the purpose of this study was to estimate the annual incidence, the mortality, and the direct and indirect costs associated with occupational injuries and illnesses in california in 1992. to achieve this, we performed aggregation and analysis of national and california data sets collected by the u.s. bureau of labor statistics, california workers' compensation insurance rating bureau, california division of industrial relations, the national center for health statistics, and the u.s. health care ...200111330988
update on the epidemiology of hiv/aids in the united states.during the past 20 years, the epidemic of human immunodeficiency virus and acquired immunodeficiency syndrome in the united states has continually evolved. beginning in the mid-1990s, the numbers of annual aids cases and aids deaths have decreased, due in large measure to effective combination anti-retroviral therapies, which prolong the survival of people infected with hiv and delay progression to aids. this has resulted in an increase in the number of people living with hiv infection or aids. ...200111324111
osha 2000: a review of compliance issues.the california occupational safety and health administration is responsible for enforcing worker safety regulations in the state of california. the infection control regulation, while the best known to dentists, is only one of many that affect every dental practice. the past two years have brought significant changes to cal/osha rules. this paper reviews some of the current regulations that apply to dental offices.200011324046
gene-environment interactions in renal cell carcinoma.the majority of renal cell carcinomas (rccs) are sporadic, and increasing incidence rates suggest that such environmental risk factors as smoking play a role in the etiology of the disease. cases with rcc were selected from the population-based cancer registry of orange county, california, between 1994 and 1997; controls were recruited by telephone using random digit dialing. a total of 115 case and 259 control subjects were genotyped for n-acetyltransferase 2 (nat2), which codes for a polymorph ...200111323315
haart adherence in culturally diverse patients with hiv/aids: a study of male patients from a veteran's administration hospital in northern california.the objective of this study was to identify the factors that influence adherence to antiretroviral medication regimens in culturally diverse populations with human immunodeficiency virus/acquired immune deficiency syndrome (hiv/aids) related to age, ethnicity, and intravenous drug use. the critical incident technique was used to identify factors determining adherence. through a series of brief, focused interviews, patients were asked to recall specific incidents that affected their adherence to ...200111313024
paleoepidemiolgical patterns of trauma in a prehistoric population from central california.skeletal trauma was investigated in a large collection of human remains from central california (n = 162 aged and sexed adults). lesions investigated included cranial and long bone fractures, projectile wounds, and dislocation. long bone fractures were found in 10.5% of individuals; overall, incidence by element was 2.3%. in addition, cranial injuries were found in 4.4% of complete adult crania. projectile wounds were seen unambiguously in four individuals (with embedded obsidian fragments) and ...200111309746
voluntary screening program for hiv in pregnancy. cost effectiveness.to determine the effectiveness of a voluntary human immunodeficiency virus (hiv) screening program in pregnancy.200111304866
suboptimality in human categorization and identification.categorization and identification decision processes were examined and compared in 4 separate experiments. in all tasks, the critical stimulus component was a line that varied across trials in length and orientation, and the optimal decision rules were always complex piecewise quadratic functions. evidence was found that identification is mediated by separate explicit and implicit systems. in addition, a common type of suboptimality was found in both categorization and identification. in particu ...200111293461
molecular evidence of bartonella spp. in questing adult ixodes pacificus ticks in california.ticks are the vectors of many zoonotic diseases in the united states, including lyme disease, human monocytic and granulocytic ehrlichioses, and rocky mountain spotted fever. most known bartonella species are arthropod borne. therefore, it is important to determine if some bartonella species, which are emerging pathogens, could be carried or transmitted by ticks. in this study, adult ixodes pacificus ticks were collected by flagging vegetation in three sites in santa clara county, calif. pcr-res ...200111283031
human and pet-related risk factors for household evacuation failure during a natural disaster.this study characterized risk factors for household evacuation failure. a random digit dial telephone survey was conducted of 397 households in yuba county, california, in july 1997, 6 months after residents had been under evacuation notice due to flooding. case households failed to evacuate, whereas control households evacuated. the cumulative incidence of household evacuation failure was 19.4%. fewer households with children (25.8%) failed to evacuate than households without children (45.9%, p ...200111282793
the phylogenetics of mycotoxin and sclerotium production in aspergillus flavus and aspergillus oryzae.aspergillus flavus is a common filamentous fungus that produces aflatoxins and presents a major threat to agriculture and human health. previous phylogenetic studies of a. flavus have shown that it consists of two subgroups, called groups i and ii, and morphological studies indicated that it consists of two morphological groups based on sclerotium size, called "s" and "l." the industrially important non-aflatoxin-producing fungus a. oryzae is nested within group i. three different gene regions, ...200011273679
multivariate patterns of biochemical responses of pinus ponderosa trees at field plots in the san bernardino mountains, southern california.most environmental stress conditions promote the production of potentially toxic active oxygen species in plant cells. plants respond with changes in their antioxidant and photoprotective systems. antioxidants and pigments have been widely used to measure these responses. because trees are exposed to multiple man-made and natural stresses, their responses are not reflected by changes in single stress markers, but by complex biochemical changes. to evaluate such response patterns, explorative mul ...200111262924
cost and effectiveness of the california triple marker prenatal screening program.to report the utilization of services offered and pregnancy outcomes for a unique statewide prenatal triple marker screening program and to present a cost-benefit analysis. a state population of 32 million with considerable ethnic and age distribution and with a wide variety of delivery systems providing prenatal care was considered. the entire pregnant population who appeared for care before 20 weeks gestation, approximately one-half million per year during the years of 1995 to 1997, was includ ...199911256673
human herpesvirus 8 infection and kaposi's sarcoma among human immunodeficiency virus-infected and -uninfected women.little is known about the epidemiology of human herpesvirus 8 (hhv-8) infections among women. a cross-sectional study was conducted of hhv-8 infection among human immunodeficiency virus (hiv)-infected and high-risk hiv-uninfected women. serological tests with noninduced (latent) and induced (lytic) hhv-8 antigens were used to detect infection among 2483 participants of a multisite cohort. reactivity to latent antigen was present in 4.1% and to induced antigens in 12.0% of women. seven of 8 women ...200111237842
from the centers for disease control and prevention. human rabies--california, georgia, minnesota, new york and wisconsin, 2000. 200111236749
disaster public health considerations.this paper provides an overview of disaster public health preparedness, response, and recovery activities with particular reference to examples that have occurred in california. it discusses the public health considerations from two aspects: 1) general public health effects; and 2) public and environmental health control measures. the latter discussion is divided into: 1) drinking water; 2) human wastes; 3) food; 4) personal hygiene; 5) mass care and shelter; 6) solid waste and debris; 7) hazard ...200011227603
adolescent substance use and sexual risk-taking behavior.to examine the relationship of adolescent substance use and dependence to sexual risk-taking behavior in late adolescence and young adulthood.200111226840
[teaching human anatomy by the american medical faculty. the example of stanford]. 200111210586
dye dispute leans amersham's way. 200111196606
non-hodgkin's lymphoma: pathogenesis, clinical presentation, and treatment. 200111191128
stem the human, financial toll of drug abuse in pregnancy. 200011188286
my body, my body parts, my property?this paper challenges the view, commonly held in biolaw and bioethics, that there can be no proprietary rights in our own bodies or body parts. whether the starting point is the post-intervention informed consent regime of article 22 of the convention of human rights and biomedicine or the traditional (exclusionary) understanding of private property it is argued that property in our own bodies or body parts is presupposed. although these arguments do not demonstrate that there is property of thi ...200011183448
the changing economics of hiv care.new advances in human immunodeficiency virus (hiv) monitoring and therapeutics have led to dramatic changes in the course of hiv disease. we evaluated our closed clinic of 425 hiv patients over the period 1995-1998 to determine the cost effectiveness of these changes in care. we found that the costs of antiretroviral therapy tripled over the period of observation, but that these increases were largely offset by major declines in inpatient and home health expenditures. in addition, we found that ...200111177585
unsuccessful voluntary prenatal testing for human immunodeficiency virus infection.within the kaiser permanente system of northern california, testing for hiv during prenatal vis its was encouraged. during a 5-year period the percentage of women agreeing to hiv testing increased from 50% to 76%. eighty-three hiv-positive pregnancies occurred in 63 women. only 17 (20%) of the 83 pregnancies were identified by the voluntary testing program.200111176574
innovative mentoring programs to promote gender equity in academic medicine.the authors describe the history, characteristics, and goals of four innovative programs, each in a medical school, that were established in 1998 to help faculty members of both sexes obtain mentors and thereby facilitate their career advancement. the programs were established as the result of an initiative by the office on women's health (owh) within the u.s. department of health and human services. specifically, the owh convened the national task force on mentoring for health professionals, wh ...200111154192
a genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22.bipolar disorder or manic depressive illness is a major psychiatric disorder that is characterized by fluctuation between two abnormal mood states. mania is accompanied by symptoms of euphoria, irritability, or excitation, whereas depression is associated with low mood and decreased motivation and energy. the etiology is currently unknown; however, numerous family, twin, and adoption studies have argued for a substantial genetic contribution. we have conducted a genome survey of bipolar disorder ...200111149935
it wasn't about race. or was it?hope barrows, a partner at the national accounting firm fuller fenton, drove to the office on sunday and swiped her access card to enter the parking garage. she noticed that another car followed her in--without using an access card. hope could see that the driver was a man, but she didn't recognize him. concerned for her safety, she got out and asked to see his id. dillon johnson, an associate at the same firm, was rushing to meet a colleague to review a client's file. seeing the garage door was ...200011143153
emergence of domestically acquired ceftriaxone-resistant salmonella infections associated with ampc beta-lactamase.ceftriaxone, an expanded-spectrum cephalosporin, is an antimicrobial agent commonly used to treat severe salmonella infections, especially in children. ceftriaxone-resistant salmonella infections have recently been reported in the united states, but the extent of the problem is unknown.200011135779
human adenoviruses and coliphages in urban runoff-impacted coastal waters of southern california.a nested-pcr method was used to detect the occurrence of human adenovirus in coastal waters of southern california. twenty- to forty-liter water samples were collected from 12 beach locations from malibu to the border of mexico between february and march 1999. all sampling sites were located at mouths of major rivers and creeks. two ultrafiltration concentration methods, tangential flow filtration (tff) and vortex flow filtration (vff), were compared using six environmental samples. human adenov ...200111133443
occurrence of fumonisins and moniliformin in corn and corn-based food products of u.s. origin.food-grade corn and corn-based food products intended for human consumption were analyzed for the incidence and levels of fumonisin b1 (fb1), fumonisin b2 (fb2), moniliformin, and fusarium molds. a total of 100 food-grade commercial corn samples were obtained from two corn processing companies at five different locations in the united states. seventy-one percent of the samples contained fb1 with concentrations ranging from 43 to 1,642 microg/kg. none of the samples contained fb2. fifty percent o ...200011131899
survey of veterinary conference attendees for evidence of zoonotic infection by feline retroviruses.to examine exposure risks, possibility of zoonosis, and potential disease associations for feline retroviruses among a group of occupationally exposed individuals.200011128537
linkage of the dopamine d4 receptor gene and attention-deficit/hyperactivity disorder.there is considerable evidence supporting a genetic component in the etiology of attention-deficit/hyperactivity disorder (adhd). because stimulant medications act primarily on the dopaminergic system, dopamine system genes are prime candidates for genetic susceptibility factors for adhd. previous studies by several groups have observed a significant association of adhd and an allele with 7 copies of the 48 base pair repeat in the third exon of the dopamine d4 receptor.200011128331
distribution of particulate matter and tissue remodeling in the human lung.we examined the relationship between intrapulmonary particle distribution of carbonaceous and mineral dusts and remodeling of the airways along anatomically distinct airway paths in the lungs of hispanic males from the central valley of california. lung autopsy specimens from the fresno county coroner's office were prepared by intratracheal instillation of 2% glutaraldehyde at 30 cm h(2)o pressure. two distinct airway paths into the apico-posterior and apico-anterior portions of the left upper l ...200011102298
trends in intussusception-associated hospitalizations and deaths among us infants.the newly licensed tetravalent rhesus-human reassortant rotavirus vaccine has been withdrawn following reports of intussusception among vaccinated infants.200011099597
lilly and stanford to establish hepatitis program for excellence. 199911082732
sinonasal nk/t-cell lymphomas in the united states.sinonasal natural killer (nk)/t-cell lymphomas are common in asia and areas of south and central america but are rarely seen in the united states, where they have not been as well characterized. fifteen cases diagnosed in southern california were studied with respect to histologic features, immunophenotype, epstein-barr virus eber in-situ hybridization (ebv eber-ish), and t-cell receptor gamma chain (tcr-gamma) gene rearrangement. although ethnic background was available for only seven patients, ...200011075852
survey research in disaster public health.while much has been learned during the past three decades of research in the disaster field, there still are some major gaps in knowledge. the need for more and better research on the health aspects of disasters is especially noted. often, research into the health aspects has been anecdotal in nature and suffers from poor documentation of human losses. however, there are valid research methodologies that can be adapted to better document losses, evaluate interventions, and set priorities for inv ...200011066844
coyotes (canis latrans) as the reservoir for a human pathogenic bartonella sp.: molecular epidemiology of bartonella vinsonii subsp. berkhoffii infection in coyotes from central coastal california.bartonella vinsonii subsp. berkhoffii was originally isolated from a dog suffering infectious endocarditis and was recently identified as a zoonotic agent causing human endocarditis. following the coyote bite of a child who developed clinical signs compatible with bartonella infection in santa clara county, calif., this epidemiological study was conducted. among 109 coyotes (canis latrans) from central coastal california, 31 animals (28%) were found to be bacteremic with b. vinsonii subsp. berkh ...200011060089
economic evaluation of safer choices: a school-based human immunodeficiency virus, other sexually transmitted diseases, and pregnancy prevention program.to evaluate the cost-effectiveness and cost benefit of safer choices, a school-based human immunodeficiency virus, other sexually transmitted diseases, and unintended pregnancy prevention intervention for high school students.200011030854
from the centers for disease control and prevention. update: newborn screening for sickle cell disease--california, illinois, and new york, 1998. 200011023385
design and use of clinical ontologies: curricular goals for the education of health-telematics professionals.in computer science, the notion of a domain ontology--a formal specification of the concepts and of the relationships among concepts that characterize an application are a--has received considerable attention. in human-computer interaction, ontologies play a key role in defining the terms with which users and computer systems communicate. such ontologies either implicitly or explicitly drive all dialogs between the computer and the user. in the construction of health-telematics applications, pro ...200011010333
why don't we have enough cornea donors? a literature review and survey.organ donation provides a second chance for those who have experienced severe disease or injury. unfortunately there is a huge discrepancy between the supply and demand of transplantable organs, despite the existence of sufficient numbers of potential donors. through a review of the literature and a survey of optometry students, this article provides insight into the reasons for the shortage of corneal donors and how more corneal donors might be obtained.200010998945
the effect of hfe genotypes on measurements of iron overload in patients attending a health appraisal clinic.the gene that causes most cases of hereditary hemochromatosis is designated hfe. three mutations exist at this locus at a relatively high gene frequency.200010979877
molecular detection of an ehrlichia-like agent in rainbow trout (oncorhynchus mykiss) from northern california.ehrlichia dna was identified by nested pcr in rainbow trout (oncorhynchus mykiss) collected from a creek in northern california where potomac horse fever is endemic. ehrlichia dna was found in tissues from several organs including the gills, heart, spleen, liver, kidneys and intestine of trout and from three different adult digenetic trematodes (deropegus sp., crepidostomum sp., creptotrema sp.) parasitizing the gallbladder and/or the intestine of the trout. sequencing of pcr-amplified dna from ...200010962157
prevalence and correlates of herpes simplex virus type 2 infection in a population-based survey of young women in low-income neighborhoods of northern california. the young women's survey team.herpes simplex virus type 2 (hsv-2) is one of the most common sexually transmitted infections and may enhance transmission of hiv. however, population-based estimates of hsv-2 prevalence and correlates of infection are rare.200010949430
serologic and molecular evidence of ehrlichia spp. in coyotes in california.in order to determine the role of coyotes in the epidemiology of granulocytic and monocytic ehrlichial agents in california (usa), we tested 149 serum samples for antibodies against ehrlichia equi, e. risticii, and e. canis, using an indirect immunofluorescent antibody test. polymerase chain reaction (pcr) assay was used to survey for the presence of members of the e. phagocytophila genogroup, e. risticii and e. canis in blood samples of 95 coyotes. sixty-eight (46%) samples were seropositive fo ...200010941735
air toxics and health risks in california: the public health implications of outdoor concentrations.of the 188 hazardous air pollutants (haps) listed in the clean air act, only a handful have information on human health effects, derived primarily from animal and occupational studies. lack of consistent monitoring data on ambient air toxics makes it difficult to assess the extent of low-level, chronic, ambient exposures to haps that could affect human health, and limits attempts to prioritize and evaluate policy initiatives for emissions reduction. modeled outdoor hap concentration estimates fr ...200010859786
ocular onchocerca infections in two dogs in western united states.two dogs, one from california and one from arizona, were found to have aberrant infections caused by filarial nematodes of the genus onchocerca. in both cases, the parasites are localized in or near the eye. in one case the worm was located in the cornea and was surgically removed. in the second case, a very marked granulomatous reaction was induced in the retrobulbar space, mimicking an abscess. this eye was enucleated. the worms in both instances were female, and were gravid, i.e. contained mi ...200010856819
prevalence of hiv infection, sexually transmitted diseases, and hepatitis and related risk behavior in young women living in low-income neighborhoods of northern california.to estimate the prevalence of human immunodeficiency virus (hiv) infection, sexually transmitted diseases, and hepatitis and the associated sexual and drug-using behavior among women residing in low-income neighborhoods in 5 northern california counties.200010854379
kaiser permanente tele-home health research project.in summary, the quality of care and satisfaction measures of the two systems are remarkable for what they are not--that is, not different. they suggest no difference between a culturally accepted model of care, with roots extending deep into human experience, both personal and traditional, and one based on a radical departure therefrom--care in the physical absence of a carer. they suggest, they do not indicate, because the study was not designed as a direct comparison. numbers were small. other ...200010848026
current and future trends in demographics of veterinary medicine in california.to evaluate the present and future supply of veterinarians in california, in light of changing trends in animal ownership.200010844966
phylogenetic relationships of human and wildlife piroplasm isolates in the western united states inferred from the 18s nuclear small subunit rna gene.the 18s nuclear small subunit ribosomal rna gene of piroplasms from wildlife and human cases of babesiosis in the western usa were isolated by pcr and sequenced. phylogenetic analyses of these sequences and comparisons with sequences from other babesia and theileria species revealed that piroplasm isolates from the human cases were indistinguishable from some of the isolates from the western wildlife species, most notably the isolates from mule deer (odocoileus hemionus). these results suggest t ...200010840978
ehrlichia equi infection of horses from minnesota and wisconsin: detection of seroconversion and acute disease investigation.equine granulocytic ehrlichiosis (ege) is caused by infection with ehrlichia equi. ege has been reported primarily in northern california, where e equi is transmitted by the tick ixodes pacificus. reports of ege and the emergence of human granulocytic ehrlichia in minnesota prompted a seroprevalence study of e equi in horses of minnesota and wisconsin. tick (ixodes scapularis) endemic areas of minnesota and wisconsin were compared to nonendemic regions of minnesota. indirect fluorescent antibody ...200010830537
remote sensing and geographic information systems: charting sin nombre virus infections in deer mice.we tested environmental data from remote sensing and geographic information system maps as indicators of sin nombre virus (snv) infections in deer mouse (peromyscus maniculatus) populations in the walker river basin, nevada and california. we determined by serologic testing the presence of snv infections in deer mice from 144 field sites. we used remote sensing and geographic information systems data to characterize the vegetation type and density, elevation, slope, and hydrologic features of ea ...200010827114
fatal yellow fever in a traveler returning from venezuela, 1999.on september 28, 1999, a previously healthy 48-year-old man from california sought care at a local emergency department (ed) and was hospitalized with a 2-day history of fever (102 f [38.9 c]), chills, headache, photophobia, diffuse myalgias, joint pains, nausea, vomiting, constipation, upper abdominal discomfort, and general weakness. on september 26, he had returned from a 10-day trip to venezuela. on september 29, an infectious disease physician from the ed contacted the marin county health d ...200010825087
exposure assessment of trichloroethylene.this article reviews exposure information available for trichloroethylene (tce) and assesses the magnitude of human exposure. the primary sources releasing tce into the environment are metal cleaning and degreasing operations. releases occur into all media but mostly into the air due to its volatility. it is also moderately soluble in water and can leach from soils into groundwater. tce has commonly been found in ambient air, surface water, and groundwaters. the 1998 air levels in microg/m(3) ac ...200010807565
guide to community preventive services: a commentary.this article presents the comments of len duhl, md, on the guide to community preventive services. according to duhl, health suffers when the bottom line is cost-effectiveness and profit and not basic human and health needs. this indicates that social values differ. even nonmonetary, spiritual values are critical to communities. duhl based this statement on the situations cited in the article. the first situation involved the story reported by a student on the outbreak of malaria and the tr ...200010806973
detection of anti-arboviral immunoglobulin g by using a monoclonal antibody-based capture enzyme-linked immunosorbent assay.monoclonal antibody (mab)-based capture enzyme-linked immunosorbent assays (elisas) for the detection of anti-arboviral immunoglobulin g (igg elisas) were developed for a comprehensive array of medically important arboviruses from the alphavirus, flavivirus, and bunyavirus genera. tests were optimized and standardized so that maximum homology could be maintained among working parameters for the different viral agents, enabling a wide range of viruses to be easily tested for at one time. mabs wer ...200010790108
the postmortem fate of pat gregory: a disinterred native american.in late june 1990, the mono county sheriffs department in bridgeport, ca contacted the physical anthropology human identification laboratory (pahil) at california state university, chico to seek assistance in the identification of a recently discovered skull. to assist with possible identification, the cranium received a classic physical anthropological/morphological analysis to suggest the decedent's sex, age at death, ancestral affiliation, and uniqueness. it was concluded the cranium was that ...200010782980
weight change during lactation does not alter the concentrations of chlorinated organic contaminants in breast milk of women with low exposure.the purpose of this longitudinal study was to evaluate whether a loss of body fat during lactation between 4 and 20 wk postpartum increases the concentration of environmental contaminants in breast milk. we examined this relationship in two different cohorts of exclusively breastfeeding women: (1) california women with low exposure to contaminants (n = 10 whose weight was stable [mean change, 0.0 +/- 0.2 kg] and n = 11 who lost weight [mean loss, -4.1 +/- 0.4 kg]) and (2) hispanic women (n = 30) ...199910776181
overcoming language barriers for non-english speaking patients.although some of the resources or services listed may seem expensive, it is cheaper to use these than to face a malpractice suit for failure to provide patients with limited english access to services equal to those provided to english speakers. the university of california at san francisco (ucsf), one of the top three ranking research hospitals in the u.s., had a suit filed against it by the american civil liberties union (aclu) claiming failure to provide adequate translation services for the ...199910776079
fundamentals of health risk assessment. use, derivation, validity and limitations of safety indices.we investigated the way results of human health risk assessments are used, and the theory used to describe those methods, sometimes called the "nas paradigm." contrary to a key tenet of that theory, current methods have strictly limited utility. the characterizations now considered standard, safety indices such as "acceptable daily intake," "reference dose," and so on, usefully inform only decisions that require a choice between two policy alternatives (e.g., approve a food additive or not), dec ...199910765402
impact of antivirals and emergence of drug resistance: hsv-2 epidemic control.genital herpes, caused by herpes simplex virus type-2 (hsv-2), affects more people world-wide than any other sexually transmitted disease (std). antivirals are effective in decreasing the duration of symptoms and in reducing viral shedding; however, currently antiviral usage is extremely low. increased usage of antivirals would have a beneficial epidemic-level effect (due to the decreased transmission of drug-sensitive strains) as well as potentially a detrimental epidemic-level effect (if drug- ...200010763542
non-steroidal anti-inflammatory drugs and bladder cancer prevention.inclusion of phenacetin among 'proven' human carcinogens by the iarc in 1987, raised concerns about the carcinogenic potential of acetaminophen, its major metabolite. acetaminophen has been implicated as a possible causal agent in the development of cancer of the renal pelvis. the bladder and renal pelvis, which derive from the same embryological structure, share the same transitional type of epithelium. past studies have been inconclusive on the possible relationship among these analgesics and ...200010755416
related strains of mycobacterium avium cause disease in children with aids and in children with lymphadenitis.sequence analysis of the ribosomal internal transcribed spacer of 56 mycobacterium avium complex isolates from pediatric patients with aids or lymphadenitis revealed (similar to the situation in adults) that the closely related mav-b and mav-a sequevars caused the vast majority of disease. is1245 restriction fragment-polymorphism analysis and pulsed-field gel electrophoresis revealed sets of isolates with closely related patterns among strains from patients in the boston area and among isolates ...200010753729
comparison of the nucleotide sequences of 16s rrna, 444 ep-ank, and groesl heat shock operon genes in naturally occurring ehrlichia equi and human granulocytic ehrlichiosis agent isolates from northern california.we examined 11 naturally occurring isolates of ehrlichia equi in horses and two human granulocytic ehrlichiosis agent isolates in california for sequence diversity in three genes. ehrlichia equi isolates were from sierra (n = 6), mendocino (n = 3), sonoma (n = 1), and marin (n = 1) counties, and human granulocytic ehrlichiosis (hge) agent isolates were obtained from humboldt county. pcr with specific primers for 16s rrna, 444 ep-ank and groesl heat shock operon genes successfully produced amplic ...200010747108
desert ecosystems: similarities, characteristics, and health benefits.salty bodies of water in desert zones are known worldwide. the salton sea in california, usa, and the dead sea between israel and jordan are located in arid areas at approximately the same latitude, which might explain some similarities. both the salton and dead seas have ecosystems consisting of a singular saline sea/hot desert interface. the salton sea, the largest inland body of water in california, is a saline lake in the coachella and imperial valleys. the imperial valley is one of the 10 t ...199910746738
prenatal ultrasound findings in affected and unaffected pregnancies that are screen-positive for trisomy 18: the california experience.this study investigated whether significant differences in ultrasound findings exist between trisomy 18 affected and unaffected pregnancies positive by serum screening. ultrasound reports were reviewed for 335 screen-positive women. this represented 65% of all trisomy 18 screen-positive patients who had follow-up services at any of 117 californian state-approved prenatal diagnosis centers during a six-month period from november 1, 1995 to april 30, 1996. ultrasound reports were available for 100 ...200010740201
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