Publications

transient entry of enterotoxin subunits into the periplasm occurs during their secretion from vibrio cholerae.	cholera toxin and heat-labile enterotoxin (lt) are structurally similar oligomeric proteins which are capable of being efficiently secreted from vibrio cholerae. here we report that these proteins transiently enter the periplasm of v. cholerae as they traverse the cell envelope to reach the extracellular milieu. pulse-chase experiments on v. cholerae trh7000 harboring an lt-encoding plasmid revealed that radiolabeled lt a and b subunits entered the periplasm rapidly, followed by their slow efflu ...	1987	3493239
biochemical characterization of a soluble form of the 53-kda monocyte surface antigen.	two monoclonal antibodies, mem-15 and mem-18, were prepared which recognize a monocyte 53-kda antigen. a soluble form of this antigen was found in most normal sera and in urine of some nephrotic patients. milligram amounts of this glycoprotein were isolated by immunoaffinity chromatography from urine and used for quantitative amino acid and carbohydrate analysis and n-terminal amino acid sequencing. the reactivity of the isolated antigen with several previously described monoclonal antibodies in ...	2007	3493149
structural characterization of gangliosides from murine t lymphocytes.	mouse spleen cells were prepared from cba/j mice, and t lymphocytes were selectively stimulated with the t cell mitogen concanavalin a and further propagated in the presence of the t cell growth factor interleukin-2. the t cells were metabolically labeled with d-[1-14c]galactose and d[1-14c]glucosamine, and the gangliosides were extracted and purified by deae-sepharose column chromatography. carbohydrate backbone structures of the asialogangliosides, prepared by mild acid hydrolysis, were determ ...	1987	3493135
[circadian rhythm of osteocalcin in children].		2012	3492663
hla studies of endemic african kaposi's sarcoma patients and matched controls: no association with hla-dr5.	in the search for a genetic factor involved in the etiology of kaposi's sarcoma, several studies have recently focused on a significantly increased hla determinant, dr5, as well as a decreased dr3, among patients with both the classical and the aids-related form of kaposi's sarcoma. to test the consistency of this phenomenon, we analysed the frequencies of hla immunogenetic markers in 23 histologically confirmed kaposi's sarcoma patients from central africa, where this tumor is endemic, and a lo ...	2012	3492448
listeria monocytogenes meningitis treated with trimethoprim-sulfamethoxazole.		1986	3491979
binding of [3h]skf 38393 to dopamine d-1 receptors in rat striatum in vitro; estimation of receptor molecular size by radiation inactivation.	[3h]skf 38393 (2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1h-3-benzazepine) binds with high affinity to 3,4-dihydroxyphenylethylamine (dopamine) d-1 receptors in rat striatum in vitro (kd = 7 and 14 nm in nonfrozen and frozen striatum, respectively). the number of binding sites (bmax) was approximately 80.0 pmol/g of original tissue, a value similar to the bmax for the dopamine d-1 antagonist sch 23390. nondisplaceable [3h]skf 38393 binding was approximately 45% of total binding. irradiation (0-4 ...	1987	3491877
an in vitro model for tumor progression in murine lymphoid cells.		2012	3491739
complement activation in bronchial asthma evaluated by the c3d/c3 index.	in order to demonstrate a suspected complement activation in bronchial asthma, we measured the c3d (split product of c3) and the c3d/c3 ratio in 73 adults. both are considered to be a sensitive index of complement activation. compared with the value obtained in 47 normal subjects, the c3d level and the c3d/c3 ratio level were found significantly higher in asthmatic subjects. fourteen asthmatics presented an increased c3d/c3 above the calculated limit of normality. these 14 subjects differed from ...	2012	3491553
piroxicam and gastrointestinal bleeding.	a high number of spontaneous reports of gastrointestinal bleeding were associated with the use of piroxicam in norwegian patients from 1982 to 1983. however, retrospective case studies at four norwegian hospitals showed that the majority of these cases were actually associated with the use of aspirin. the remainder of the cases were divided evenly among the four other nonsteroidal anti-inflammatory drugs (nsaids), including piroxicam, then available in norway. to further investigate the relation ...	2012	3491541
symptomatic congenital ectopic gastric mucosa in the upper esophagus.		2012	3491505
cuprophan membrane induces interleukin-1 activity.		2012	3490869
the relationship between epidermal growth factor receptors and the terminal differentiation of a431 carcinoma cells.	the replication of human epidermoid carcinoma a431 cells is inhibited by epidermal growth factor (egf), with 5 ng/ml of egf causing 50% inhibition of cellular proliferation. egf resistant clones isolated from a431 cells were able to replicate in the presence of 100 ng/ml of egf. that this insensitivity to egf was probably due to a decrease in the expression of egf receptors (egfr) on the cell surface was shown using an egfr cdna probe to detect a 68% to 85% decrease relative to parental cells in ...	1986	3490853
bradykinin-induced changes in inositol trisphosphate mass in mdck cells.	bradykinin produces increases in cytosolic calcium in mdck cells. we have extracted and separated inositol 1,4,5 trisphosphate by hplc and after-acid hydrolysis and conversion to the hexatrifluoro-acetyl derivative quantitated by negative ion chemical ionization mass spectrometry the mass of inositol trisphosphate in mdck cells. bradykinin causes an increase in the mass of inositol trisphosphate from basal levels of 152 pmoles/mg cell protein to 537 pmoles/mg cell protein by 10 secs of stimulati ...	1986	3490849
[mondini's syndrome. apropos of 2 cases].	two children presented with congenital deafness from internal ear malformations of the mondini type which had provoked recurrent attacks of meningitis due to foot of stapes fistulae. good results were obtained after vestibular plugging. anatomical pathways taken by the fistulae are described and certain important points emphasized.	2012	3490821
baseline screening mammography: one vs two views per breast.	to compare the advantages of one-view vs two-view mammography screening, films were reviewed for 2500 consecutive asymptomatic women undergoing baseline mammography. to provide screening at low cost, examinations were limited to two radiographs per breast, one each in the craniocaudal and mediolateral oblique projections, with the understanding that those few patients with detected abnormalities would require additional mammograms, taken with an individually directed, problem-solving approach, a ...	2012	3490749
use of lay opinion leaders to promote diffusion of health innovations in a community programme: lessons learned from the north karelia project.	this article describes the systematic use of lay opinion leaders in the north karelia project, a comprehensive community-based preventive cardiovascular program in finland. over 800 lay opinion leaders were trained to promote the reduction of heart disease risk factors and, after approximately 4 years, a survey was conducted to assess the long-term feasibility and self-reported effects. 267 of the 399 active lay workers surveyed were women; their median age was 52 years. the median age of the me ...	2012	3490321
nailfold capillary microscopy in connective tissue disease: a quantitative morphological analysis.	photomicrographs were taken of front line nailfold capillary loops in 18 healthy women (controls) and 42 women with established connective tissue disease (14 rheumatoid arthritis, 19 systemic lupus erythematosus, nine scleroderma). measurements were made of apex width, maximum limb and loop widths, capillary length, interpeak distance, and frequency per linear millimetre. a numerical index for assessing capillary dilatation was derived, based on the mean of the apex plus maximum limb widths. res ...	2012	3490228
plasmid penicillin resistance in vibrio cholerae: identification of new beta-lactamase sar-1.	two strains of vibrio cholerae biotype el tor, isolated in tanzania, possessed a single incc resistance plasmid of 113 kilobases. both plasmids encoded the production of a novel beta-lactamase, sar-1, which was 33,700 daltons in size and was able to hydrolyze carbenicillin as well as penicillin g. the sar-1 beta-lactamase was quite distinct from all other plasmid beta-lactamases by virtue of its unusually low isoelectric point and a combination of its size, substrate profile, and inhibition prop ...	1986	3490216
isolation and characterization of the cdna for murine granulocyte colony-stimulating factor.	a cdna sequence coding for murine granulocyte colony-stimulating factor (g-csf) has been isolated from a cdna library prepared with mrna derived from murine fibrosarcoma nfsa cells, which produce g-csf constitutively. identification of murine g-csf cdna was based on the cross-hybridization with human g-csf cdna under a low-stringency condition. the cdna can encode a polypeptide consisting of a 30-amino acid signal sequence, followed by a mature g-csf sequence of 178 amino acids with a calculated ...	1986	3489940
tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.	tumor necrosis factor type alpha (tnf-alpha) is produced by monocytes and has been purified, sequenced, and cloned from the hl-60 cell line. soluble products of monocytes stimulate endothelial cells to release multilineage hematopoietic colony-stimulating activity. to determine whether tnf-alpha could stimulate endothelial cells to produce these activities, we added recombinant human tnf-alpha to cultured human umbilical vein endothelial cells. untreated endothelial cell conditioned medium and t ...	1986	3489939
effect of transcutaneous electrical nerve stimulation on pain perception threshold and pain tolerance level of human teeth subjected to electrical stimulation.		1986	3488206
studies on interventions to prevent eltor cholera transmission in urban slums.	transmission of eltor cholera infection in endemic communities continues without diminishing because of the absence of effective intervention measures. two methods-chlorination of stored water and the use of a narrow-necked earthenware vessel (called a 'sorai') for storing the water-were found to be effective in reducing the transmission of infection among the family contacts of cholera patients. the cholera carrier rates in the chlorination and 'sorai' intervention groups were 7.3% and 4.4%, re ...	1986	3488134
increased levels of osteocalcin (serum bone gla-protein) in rheumatoid arthritis.	serum osteocalcin was measured by radio-immunoassay in 56 patients with rheumatoid arthritis (ra), and in 50 controls. mean serum osteocalcin levels were significantly higher in patients with ra. there was a positive correlation between osteocalcin and fasting mucopolysaccharide/creatinine ratio in both sexes, and between osteocalcin and fasting hydroxyproline/creatinine ratio in women. serum alkaline phosphatase activity, a less specific marker for bone formation, was also increased in ra, and ...	2012	3488088
angiodysplasia of the colon requiring emergency surgery.	three patients with massive bleeding from colonic angiodysplasia, all requiring emergency surgery, are presented. prior to operation, the bleeding source was localized by angiography and colonoscopy. by this means the resection could be limited to the right colon. during follow-up of 7 months-4 years there has been no further bleeding.	2012	3487904
stressors associated with coronary bypass surgery.	the purpose of this study was to: design and test an instrument to evaluate the incidence and severity of stressors associated with coronary bypass surgery and assess the concordance between patient and nurse perceptions of such stressors. the patient sample consisted of 30 patients recovering without complications from coronary bypass surgery. patients were white, primarily male and employed, one-third with graduate education, with a mean age of 54. the nurse sample consisted of 18 registered n ...	2012	3487775
a reawakening of interest in radionuclide brain imaging.		2012	3486952
comparing costs and efficacy of mri.		2012	3486575
personal computers: their use in a low-volume imaging department.		2012	3486574
elliptical cricoid cartilage: a unique type of congenital subglottic stenosis.	an elliptically shaped cricoid cartilage, a specific type of congenital subglottic stenosis, is described, and the laryngoscopic and radiographic findings in three cases are discussed. an "hourglass" deformity of the subglottic laryngeal airway on an anteroposterior airway radiograph is suggestive of this diagnosis.	2012	3486558
interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity.	previous studies demonstrated that endothelial cells participate actively in both anticoagulant and procoagulant reactions. although anticoagulant mechanisms predominate on the surface of quiescent endothelial cells, perturbed endothelial cells can promote coagulation through the coordinated induction of procoagulant activity and suppression of anticoagulant mechanisms. purified recombinant interleukin 1 was infused intravenously into rabbits and coagulant properties of the native aortic endothe ...	1986	3486418
suppression of lymphocyte activation and functions by a leukemia cell-derived inhibitor.	an inhibitor isolated from the serum-free culture medium of human myeloid leukemic hl-60 cells was able to suppress mitogen- and alloantigen-stimulated proliferative responses of normal lymphocytes in a dose-dependent manner. in vitro production, concentration, and purification by column chromatography and electrophoresis revealed that the inhibitor was produced constitutively, required rna synthesis, and had a molecular weight in the range of 40,000-60,000. the inhibitor was also produced in vi ...	1986	3486417
introduction to research: a basic guide to scientific inquiry.		2012	3486279
decreased serum interleukin 1 activity and monocyte interleukin 1 production in patients with fatal sepsis.	the role of interleukin 1 (il 1) in 16 patients with sepsis and 16 normal controls was investigated. thymocyte costimulation was used to assay in vitro il 1 levels produced by adherent cells in the peripheral blood, and in vivo il 1 levels in the serum. adherent cells (i.e., monocytes) from nonsurviving septic patients produced significantly less il 1 activity than cells from healthy controls or surviving patients, either spontaneously or by silica stimulation. in contrast, in vitro il 2 product ...	2012	3486093
radionuclide scintigraphy of femoral head specimens removed at arthroplasty for failed femoral neck fractures.	in order to determine the value of scintimetry as a tool for quantitative measurement of femoral head vascularity, the results of postoperative scintigraphic and histologic examination of surgically removed femoral head specimens were compared with those of preoperative radionuclide scintigraphy in 19 failed femoral neck fractures. following intravenous administration of 600 mbq of tc-99m mdp before hip replacement, the activity distribution in femoral head sections was recorded with a gamma cam ...	2012	3486078
inhibition of human liver cytochrome p-450 by omeprazole.	the effects of omeprazole on cytochrome p-450 mediated 7-ethoxycoumarin deethylation were studied in human liver microsomes. omeprazole inhibited both the high and low affinity components of deethylation, with an estimated ki of 0.03 mm for the high affinity component. the results are further evidence that the previously reported prolongation of the half-life of diazepam by omeprazole in vivo is due to inhibition of cytochrome p-450 monooxygenases.	1986	3485990
prolonged depersonalization following cannabis abuse.		2012	3485985
cannabis psychosis: a case report.		2012	3485984
management of opportunistic infections complicating the acquired immunodeficiency syndrome.	therapy of opportunistic infection in patients with the acquired immunodeficiency syndrome is frustrating, and there is no convincing evidence that aggressive treatment and/or prophylaxis other than for pneumocystis infection can significantly prolong life. while much clinical effort is expended on treating sequential life-threatening infections, the overall course is usually progressively downhill. thus, any real impact on the disease should be aimed at the causative viral agent, because it is ...	1986	3485749
gardnerella vaginitis--a guide to identification and management for the practitioner.		1986	3485708
[mast cell-affinity lymphocytes as indicator cells of the forms of hemoblastoses].	the formation of mastolymphocyte rosettes was used to determine that in chronic lymphocytic leukemia and bovine leukemia, unlike healthy people and animals as well as patients with solid tumours of different localization and hodgkin's disease, a large amount of cells appear among peripheral blood lymphocytes having membrane affinity for mast cells. this may be used as an additional criterion in laboratory diagnosis of these diseases.	1986	3485042
t lymphocyte subsets at various stages of hyperthyroid graves' disease: effect of carbimazole treatment and relationship with thyroid-stimulating antibody levels or hla status.	markers of autoimmunity in hyperthyroid graves' disease were studied at various stages of the disease in connection with hla status. the 148 patients studied were included in a long term prospective evaluation of antithyroid drug treatment. the proportions of total t lymphocytes and okt4 and okt8 positive cells in peripheral blood and circulating thyroid-stimulating antibodies were determined before treatment (m0; 46 patients), after 6 (m6; 50 patients), and 18 months (m18; 22 patients) of carbi ...	2012	3484386
[work group "implant statistik" register study data to date].		2012	3484155
[current status of pulp treatment with formocresol].		2012	3483227
improved hygiene productivity.		2012	3482572
[application of professor machtou's compactors].		2012	3482391
[histopathological changes in dental pulp in rats after irradiation of nd:yag laser].		1987	3482212
[the shear bonding strength of metal-photocuring resin in crown and bridge restoration].		2012	3482179
the development of mandibular molar tooth germs isografted in the mouse spleen.	tooth germs taken from 13-day-old embryonic mice and isografted in the spleen of adult mice were examined by light and electron microscopy. well-organized tooth structures from the early cap stage to fully developed and mineralized mature teeth were obtained up to day 60 after transplantation. germs on day 2 were similar to those prior to the onset of grafting but reached the late cap stage of development on day 4. on day 6, enamel and dentine formation were initiated and inner enamel epithelium ...	1987	3482151
a study of the words used to describe pain.		2005	3481252
effects of dietary fish oil on renal insufficiency in rats with subtotal nephrectomy.	we studied the effects of fish oil on the progression of renal insufficiency in rats with subtotal nephrectomy. five weeks after a 1-2/3 nephrectomy, sixteen rats were fed two different diets which differed only in fat composition. lipid in the control diet was primarily beef tallow; that of the experimental diet, menhaden oil. fish oil-fed rats had significant increases in plasma creatinines, decreases in urinary pge2 and accelerated death rates. an additional twelve rats underwent 1-1/3 nephre ...	1987	3480973
13-cis-retinoic acid and its effect on the liver of the egyptian toad.		2012	3480846
endotoxins in poultry production and human lung reactions.		1987	3480834
the sensitivity of gram-negative and gram-positive bacteria to ofloxacin.	the in vitro antimicrobial activity of ofloxacin, a new fluorinated quinolone, was evaluated against 165 gram-negative rods, both fermentative and non-fermentative, and against 57 gram-positive strains (coagulase-positive and -negative staphylococci both methicillin-resistant and -susceptible, and streptococcus faecalis). minimal inhibitory concentrations were determined by using the macrodilution test and the activity was compared with nalidixic acid, norfloxacin, ampicillin, piperacillin, ceft ...	1987	3480796
the avulsed tooth.		2012	3480721
vascular variance--scylla and charybdis?		2012	3479865
drugs in dentistry. medications for gingival hyperplasia.		2012	3479350
inhibition of the synthesis of glycoproteins and induction of the differentiation of hl-60 promyelocytic leukemia cells by 6-methylmercaptopurine ribonucleoside.	hl-60 promyelocytic leukemia cells were induced to differentiate along the granulocytic pathway by exposure to 6-methylmercaptopurine ribonucleoside (6-mmpr). the interference with cellular replication and the induction of terminal maturation by 6-mmpr appeared to be a consequence of the inhibition of purine nucleotide biosynthesis de novo, since the simultaneous exposure of hl-60 cells to 6-mmpr and adenine completely prevented cellular differentiation, as measured by both nitro-blue tetrazoliu ...	2012	3479242
conformation of protein secreted across bacterial outer membranes: a study of enterotoxin translocation from vibrio cholerae.	the secretion of enterotoxin by vibrio cholerae is punctuated by the transient entry of the toxin subunits into the periplasm. in this paper, we show that the subunits oligomerize into an assembled holotoxin within the periplasm prior to their secretion across the outer membrane. the rate of toxin assembly was studied by pulse-labeling cells with [35s]-methionine and then monitoring the turnover of radiolabeled subunits as they assembled within the periplasm. the subunits entered the periplasm a ...	1987	3478701
subcutaneous nonparenchymal hemangioma of the breast.		2012	3478625
inducible reactivation of uv-irradiated cholera phage e5 in vibrio cholerae mak757.	the survival of uv-irradiated cholera phage e5 was found to increase when the host cells, vibrio cholerae mak757, were exposed to a low dose of uv irradiation before phage infection (weigle reactivation), indicating the existence of a uv-inducible dna repair pathway (sos repair) in v. cholerae mak757. the induction signal generated by uv irradiation was transient in nature and lasted about 20-30 min at 37 degrees c. maximal weigle reactivation of the phage was obtained when the host cells were i ...	1987	3478551
[oral surgery in children's dentistry].		2012	3478241
comparative biodistributions and rates of catabolism of radiolabelled anti-cea monoclonal antibody and control immunoglobulin in nude mice with human tumour xenografts showing specific antibody localization.	the rate of catabolism of a radiolabelled monoclonal anti-cea antibody has been compared with that of control igg1 in control nude mice and in mice with cea producing xenografts and antigen negative xenografts. the rate of catabolism of antibody, but not of igg, was increased 3-4 fold in mice with xenografts localizing the antibody, but not in mice with antigen negative tumours. there was no evidence of immune complex formation and/or clearance of antibody from the serum of xenografted mice and ...	1987	3478194
a clinico-pathologic presentation. amalgam pigmentation.		2012	3477607
community dental service, cash-limited sector of primary medical and dental care.		2012	3477312
management of uterine hyperstimulation after prostaglandin e2 administration.	recent literature suggests that intravaginal or intracervical application of prostaglandin e2 gel may be an effective agent for cervical ripening. one potentially disastrous reported side effect is uterine hyperstimulation. this case report represents the first description of the successful management of uterine hyperstimulation with intravenous ritodrine therapy after the intravaginal administration of prostaglandin e2.	2012	3476877
case-control study on histologically determined multiple primary lung cancer.	between 1965 and 1985, 72 (64 male and 8 female) cases of multiple primary lung cancer (mplc) in the national cancer center hospital, japan, were reviewed, and a retrospective hospital-based case-control study was performed with special reference to the patients' smoking and family histories. control cases were selected from patients with unicentric lung cancer (ulc) with a longer survival time than that for other patients with whom they were matched for age, sex, histologic examination of prima ...	2008	3476786
case-control study on histologically determined multiple primary lung cancer.	between 1965 and 1985, 72 (64 male and 8 female) cases of multiple primary lung cancer (mplc) in the national cancer center hospital, japan, were reviewed, and a retrospective hospital-based case-control study was performed with special reference to the patients' smoking and family histories. control cases were selected from patients with unicentric lung cancer (ulc) with a longer survival time than that for other patients with whom they were matched for age, sex, histologic examination of prima ...	2008	3476786
microbiological study on early plaque formation in partial denture wearers.		1987	3476293
legal techniques and medical value judgments.		2002	3476055
[geriatric pharmacology].		2012	3475806
evaluation of the comparative effectiveness of fluoride mouthrinsing, fluoride tablets, and both procedures in combination: interim findings after two years.		2012	3475680
salivary ph and glucose after consuming various beverages, including sugar-containing drinks.		2007	3475181
fracture of polycarbonate edgewise brackets: a clinical and sem study.	fracture experience and fracture form of polycarbonate edgewise brackets, were assessed in a clinical study using four force controlled mechanical systems. the incidence and types of bracket fracture were investigated macroscopically and by scanning electron microscopy (sem). it was concluded that the engagement of both round and square archwires and stainless steel ligaturing were aetiological factors in bracket fracture.	2012	3475125
alcohol and the cell.		2012	3474919
rhizomegaly--teeth with extremely long roots (a case report).		2012	3474289
salt-induced plasma factor that inhibits platelet thromboxane a2 release and renal prostaglandin e2 production in rats.	this study examined the relationship between a plasma factor (or factors) that inhibits the release of thromboxane a2 from platelets and excessive salt intake in rats. the plasma factor, termed platelet inhibitory factor, was also characterized. the release of thromboxane a2 from thrombin-activated platelets was reduced in wistar rats that were uninephrectomized and given 2% saline for a week, but not in rats with acute volume expansion. platelet inhibitory factor was extracted from the plasma o ...	1987	3474209
[isolation of the r'his plasmids of vibrio cholerae].	v. cholerae strain vt5104 capable of donor activity in conjugation has been constructed by the genetic technique based on plasmid rp4::mucts62 integration into v. cholerae chromosome due to plasmid homology with mucts62 inserted into the chromosome. the gene for histidine synthesis has been mobilized and transferred into the recipient cells from vt5104 donor. the conjugants obtained are able to efficiently transfer his+ gene included into the plasmid structure in conjugation with eltor recipient ...	1987	3474038
immunotoxins to a human melanoma-associated antigen: resistance to pokeweed antiviral protein conjugates in vitro.	pokeweed antiviral protein (pap) from the summer leaves of phytolacca americana was purified and conjugated via n-succinimidyl-3-(2-pyridyldithio)propionate to 9.2.27 anti-melanoma antibody to a glycoprotein-proteoglycan complex. the conjugate was highly potent (50% inhibition dose of 5 x 10(-11)-10(-13) m on antigen-positive melanoma) and highly selective (5 x 10(-8) on antigen-negative melanoma). human melanoma cells were selected for resistance to in vitro killing of the pap conjugate by cycl ...	1987	3473251
factors affecting successful prognosis of root canal treatment.		2001	3473180
gardner's syndrome with bilateral osteomas of coronoid process resulting in limited opening.		2012	3472187
[hemodynamic changes in coronary heart disease and its therapy].		2011	3472028
considerations for furcation treatment. part ii: periodontal therapy.		2012	3471953
gingival lesions caused by improper oral hygiene measures.		2012	3471735
unusual foreign body in alveolus.		2012	3471641
application of knowledge of metabolic integration to the problem of metabolic limitations in middle distance and marathon running.		2012	3471062
scleral allografts: a retrospective clinical study.		2012	3470817
role of sialic acid in synaptosomal transport of amino acid transmitters.	active, high-affinity, sodium-dependent uptake of gamma-aminobutyric acid and of the acidic amino acid d-aspartate was inhibited by pretreatment of synaptosomes with neuraminidase from vibrio cholerae. inhibition was of a noncompetitive type and was related to the amount of sialic acid released. the maximum accumulation ratios of both amino acids (intracellular [amino acid]/extracellular [amino acid]) remained largely unaltered. treatment with neuraminidase affected neither the synaptosomal ener ...	1987	3470752
effect of platelet-derived growth factor on enriched populations of haemopoietic progenitors from patients with chronic myeloid leukaemia.	the effect of pure platelet-derived growth factor and fresh serum on the in-vitro growth of purified haemopoietic progenitors from the peripheral blood of 12 patients with cml was studied. purified haemopoietic progenitors were prepared using percoll separation followed by cell sorting with the monoclonal antibody bi.3c5. both pure pdgf at a concentration of 20 ng/ml and fresh serum significantly increased the numbers of bfu-e (p less than 0.01) and cfu-gemm (p less than 0.014), but not the cfu- ...	2012	3470579
exocrine pancreatic neoplasms induced by methylazoxymethanol acetate in the guppy poecilia reticulata.	exocrine pancreatic neoplasms developed in the guppy poecilia reticulata following a single brief exposure to methylazoxymethanol acetate [(mam-ac) cas: 592-62-1]. fish 6-10 days old were exposed to concentrations of mam-ac up to 100 mg/liter for 2 hours. exposed specimens were transferred to carcinogen-free water and sampled periodically for tumor development. pancreatic neoplasms occurred in approximately 9% of histologically examined individuals exposed to 10 mg mam-ac/liter or less. neoplast ...	2012	3470547
detergent-assisted refolding of guanidinium chloride-denatured rhodanese. the effects of the concentration and type of detergent.	we have established the generality of using detergents for facilitating the reactivation of 6 m guanidinium chloride-denatured rhodanese that was recently described for the nonionic detergent lauryl maltoside (lm) (tandon, s., and horowitz, p. (1986) j. biol. chem. 261, 15615-15618). we report here that not only lm but other nonionic as well as ionic and zwitterionic detergents also have favorable effects in reactivating the denatured enzyme. not all detergents are useful, and the favorable effe ...	2012	3470292
[fine structure of the pollen of cryptomeria japonica].		1986	3470071
a computer for every dental office: an update.		2012	3469575
the professionalisation of nursing--collegial cooperation.		2012	3469548
monoclonal igm antibodies that inhibit primary moloney murine sarcoma growth.	monoclonal igm antibodies with specificity for moloney murine sarcoma virus (m-musv)-moloney murine leukemia virus (m-mulv) from two hybridoma clones have been isolated and characterized. the monoclonal antibodies have specificity for a cytoplasmic and cell surface friend-moloney-rauscher group-specific antigen. immunoelectron microscopy revealed antibody binding to the surface of virus-expressing cells but not to the budding virus particles. treatment of m-musv-injected mice with monoclonal igm ...	1987	3469466
[a case of acute promyelocytic leukemia diagnosed on the 5th day after delivery].		2012	3469428
[possibility of overcoming of acnu resistance in an acnu-resistant subline of c6 rat glioma].	membrane-modifying agents such as reserpine, calcium antagonists (nicardipine, verapamil) and calmodulin inhibitor (trifluoperazine) were found to enhance the cytotoxicity of acnu in vitro and in vivo in acnu-resistant c 6 (c 6/acnu) glioma. in in vitro experiments, uptake and retention studies with [14c] acnu revealed that intracellular uptake and retention of acnu in c 6 cells were larger than those in c 6/acnu cells, and that these membrane-modifying agents increased the cellular uptake and r ...	1986	3468959
extended modified postauricular incision of the temporomandibular joint.	the traditional postauricular approach to the temporomandibular joint has excellent cosmetic results since the entire incision is concealed in the postauricular flexure. excellent posterior joint exposure, good lateral joint exposure, and fair anterior joint exposure are obtained. the risk of injury to the facial nerve is decreased. an extended modification of the postauricular incision was developed to overcome some of the disadvantages of the postauricular incision while maintaining its advant ...	2012	3468462
the new journalism.		2012	3468402
surface charge of resident, elicited, and activated mouse peritoneal macrophages.	the surface charge of resident, thioglycollate-elicited, and trypanosoma cruzi-activated mouse peritoneal macrophages was analyzed using cell electrophoresis. all macrophages had a net negative surface charge. activated macrophages had a lower zeta potential and a higher isoelectrophoretic point than resident and elicited macrophages. the populations of resident, elicited, and activated macrophages were heterogeneous in terms of surface charge. the analysis of the effect of the ph of the solutio ...	1987	3468193