Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| cognitive-behavior therapy with adult patients with epilepsy: a controlled outcome study. | the present study evaluated the efficacy of group cognitive-behavior therapy for the alleviation of psychosocial problems and reduction of seizures with adult epileptic patients. twenty-seven outpatients were randomly assigned to one of three groups: cognitive-behavior therapy, supportive counseling (attention-placebo control), and waiting list (no treatment control). the major outcome measures used were: patient's, neurologist's, and therapist's global ratings of psychological adjustment, patie ... | 2012 | 3516668 |
| diffusion of thyroglobulin in the follicular colloid. (minireview). | methods used for estimating in vivo diffusion velocity of thyroglobulin (tgb), the factors affecting hydrodynamic properties of thyroidal colloid and the effects of changing diffusion properties on follicular function are briefly reviewed. the principal methods, besides pure in vitro techniques, are autoradiography of thyroid sections after in vivo labelling of tgb and freezing autoradiography for examining colloidal diffusion of ions or other small molecules. the main factors known to affect di ... | 1986 | 3516644 |
| measurement and mechanisms of breathlessness. | 2012 | 3516269 | |
| dose-response effects of methacholine in normal and in asthmatic subjects. relationship between the site of airway response and overall airway hyperresponsiveness. | we examined the dose-response curves to methacholine in 6 normal subjects and 13 asthmatics by simultaneous assessment of respiratory resistance (rrs) and anatomic dead space (vdan). methacholine was continuously inhaled in stepwise incremented concentrations during tidal breathing until a nearly twofold increase in respiratory resistance (rrs) was observed. large airway response was determined by vdan, and overall airway response was determined by rrs. small airways response was inferred from r ... | 2012 | 3516037 |
| histopathologic and antibody responses of rabbits exposed to aerosols containing spores of aspergillus fumigatus: comparison of single and multiple exposures. | resistance to pulmonary aspergillosis was studied in groups of rabbits exposed to aerosolized spores of aspergillus fumigatus for 15 minutes on successive days for a total of 10, 7, or 4 exposures or a single exposure. the results of the study demonstrated that exposure of rabbits to spores for 15 minutes on 10 successive days did not result in an accumulation of viable spores in excess of those present in the lungs of rabbits exposed a single time. the tissue response in the lungs of the rabbit ... | 1986 | 3516034 |
| [heterogeneity and variability of vibrio cholerae eltor populations and their role in the development of epidemic processes]. | 1986 | 3515813 | |
| vocational influences on prosthetic design. | 2012 | 3515392 | |
| increased fracture resistance of teeth: comparison of five bonded composite resin systems. | 2012 | 3515389 | |
| man and nature: controversy and philosophy. | 1986 | 3515387 | |
| the use of furoxone: a perspective. | acute infectious diarrhoea is a widespread cause of morbidity and mortality. some of the major diarrhoeal diseases are cholera, typhoid fever, shigellosis (bacillary dysentery), salmonellosis, "travellers' diarrhoea", and giardiasis these diseases can be avoided with proper education, sanitation, and hygiene. however, the majority of these diseases occur most frequently in areas of the world where political and social upheaval, poverty, overcrowding, and a lack of education prevail. although vac ... | 1986 | 3514312 |
| insulin and glucose levels. | 1986 | 3513673 | |
| [steristrip tape suturing compared with percutaneous suturing of abdominal incisions. a controlled study of late cosmetic results]. | 2012 | 3513415 | |
| [presacral rectopexia in rectal prolapse]. | 2012 | 3513368 | |
| the effect of lincomycin on exoprotein production by vibrio cholerae. | lincomycin has a differential effect on exoprotein production by vibrio cholerae. the production of some proteins, such as cholera toxin and deoxyribonuclease, is stimulated by low concentrations of the drug while production of other proteins, such as protease and alkaline phosphatase, is unaffected. possible mechanisms of the lincomycin effect are discussed. | 1986 | 3512830 |
| smear layer removal effects on apical leakage. | 2012 | 3512756 | |
| selection, mapping, and characterization of osmoregulatory mutants of escherichia coli blocked in the choline-glycine betaine pathway. | osmotically stressed escherichia coli cells synthesize the osmoprotectant glycine betaine by oxidation of choline through glycine betaine aldehyde (choline----glycine betaine aldehyde----glycine betaine; b. landfald and a.r. strøm, j. bacteriol. 165:849-855, 1986. mutants blocked at the level of choline dehydrogenase were isolated by selection of strains which did not grow at elevated osmotic strength in the presence of choline but grew when supplemented with glycine betaine. a gene governing th ... | 1986 | 3512526 |
| diagnosis of complex acid-base disorders: physician performance versus the microcomputer. | patients with acid-base disturbances that are often complex frequently present to the emergency department. the sometimes hectic nature of the ed can preclude the appropriate quantitative analysis required by these disorders, especially when mixed disturbances are present. a computer program using generally accepted acid-base and electrolyte formulae was developed for use on the apple ii+ or ibm-pc microcomputer. each of a series of 35 acid-base disturbances incorporating single, double, and tri ... | 2006 | 3511785 |
| diagnosis of complex acid-base disorders: physician performance versus the microcomputer. | patients with acid-base disturbances that are often complex frequently present to the emergency department. the sometimes hectic nature of the ed can preclude the appropriate quantitative analysis required by these disorders, especially when mixed disturbances are present. a computer program using generally accepted acid-base and electrolyte formulae was developed for use on the apple ii+ or ibm-pc microcomputer. each of a series of 35 acid-base disturbances incorporating single, double, and tri ... | 2006 | 3511785 |
| third generation cephalosporin antibiotics in surgical practice. | the new third generation cephalosporins have a significantly greater spectrum of action against gram-negative bacteria likely to be encountered in surgical infections. this expanded spectrum may permit these drugs to be used in place of combination therapy in patients with polymicrobial infections; however, current evidence does not indicate superior results with these agents over earlier generation choices for surgical prophylaxis. the toxicity profile of these drugs warrants close monitoring f ... | 2012 | 3511763 |
| [intensified insulin therapy by multiple injections or by pump]. | a relationship exists between metabolic control and the development of late complications of diabetes. recently, new strategies of insulin therapy have been developed to normalize blood glucose control, with a view to preventing late complications of diabetes and increasing patients' well-being. intensified insulin therapy can be performed by multiple insulin injections or by continuous subcutaneous insulin infusion with a pump; regular self-monitoring of blood glucose is mandatory with these ty ... | 2012 | 3511525 |
| cholera: a worldwide perspective. | 1986 | 3511458 | |
| vaccine prevention of haemophilus influenzae type b disease: past, present and future. | in little more than half a century we have come a long way toward the eventual elimination of invasive hib disease as a major threat to children in the united states. the haemophilus b polysaccharide vaccine has provided the first tool for large scale public health intervention efforts in specific target groups of children older than 18 months of age who are likely to benefit from immunization. immunization programs using the currently available vaccine represent an interim measure that is likel ... | 1986 | 3511454 |
| comparison of tensile and shear strength of new and recycled orthodontic metal brackets. | 2012 | 3511411 | |
| antihypertensive treatment with metoprolol or hydrochlorothiazide in patients aged 60 to 75 years. report from a double-blind international multicenter study. | in a randomized double-blind study (n = 562), a traditional treatment schedule, starting antihypertensive treatment in elderly hypertensive patients (60 to 75 years old) with 25 mg of hydrochlorothiazide once daily and doubling the dose if a satisfactory response was not achieved, was compared with antihypertensive treatment of 100 mg of metoprolol once daily, adding 12.5 mg of hydrochlorothiazide for patients whose response was not satisfactorialy achieved with metoprolol alone. systolic and di ... | 2012 | 3511308 |
| beta-lactamase-producing eikenella corrodens in an intraabdominal abscess. | 1986 | 3511160 | |
| dentistry on stamps. | 2012 | 3511120 | |
| the far-near/near-far suture. | 2012 | 3511112 | |
| glutamine is responsible for stimulating glycolysis by l929 cells. | l929 cells synthesize relatively little lactate when using glucose as their primary energy source, and neither glucose oxidation nor lactate production is highly sensitive to stimulation by insulin. addition of glutamine to the system containing glucose and insulin markedly stimulates lactate production from glucose without inhibiting glucose oxidation. a mechanism in which reducing equivalents derived from glutamine oxidation are used to drive lactate production is discussed. | 2012 | 3511079 |
| asbestos exposure--quantitative assessment of risk. | methods for deriving quantitative estimates of asbestos-associated health risks are reviewed and their numerous assumptions and uncertainties described. these methods involve extrapolation of risks observed at past relatively high asbestos concentration levels down to usually much lower concentration levels of interest today--in some cases, orders of magnitude lower. these models are used to calculate estimates of the potential risk to workers manufacturing asbestos products and to students enro ... | 2012 | 3510581 |
| demonstration of the "no-reflow" phenomenon by digital coronary arteriography. | 2012 | 3510523 | |
| restless legs syndrome. | patients with restless legs syndrome often have difficulty describing their symptoms. three features characterize the classic syndrome: an unusual, almost indescribable sensation in the lower extremities; an irresistible urge to move the legs, and the exclusive occurrence of the symptoms at rest, with their relief by movement. restless legs syndrome may cause severe insomnia. variants of the syndrome, as well as numerous associated conditions, have been described. the etiology is unknown. clonaz ... | 2012 | 3510520 |
| cutaneous necrotic arachnidism. a case report. | 2012 | 3510292 | |
| a radiosensitive t-lymphocyte associated with resistance of dba/2 mice harboring friend leukemia virus-dormant infections to transplantable friend leukemia virus-erythroleukemia cells. | the immunobiology of friend erythroleukemia virus (flv) has been the focal point of much research into immunological control of leukemia. we have been studying a murine model in which a rapidly fatal flv infection of dba/2 mice is suppressed to a dormant state by treatment with statolon, a double stranded rna extract of mycoplasma stoloniferum. we report here that mice with flv-dormant infections resist the accumulation of transplanted flv-transformed erythroleukemia cells (flc-745) and that flc ... | 1986 | 3509990 |
| selection of reference preparation. iuis reference preparation criteria. international union of immunological societies. | 2012 | 3509970 | |
| essays on the art of caring in nursing: i. the human spirit in stress management. | 1987 | 3509708 | |
| ofloxacin pharmacokinetics in renal failure. | 2012 | 3509428 | |
| [problems and methods of the care of postoperative patients with cancer of the thoracic esophagus]. | 2012 | 3509222 | |
| [the concept of disease and causality relations]. | the author recalls the doctrinal and jurisprudential evolution of the concept of disease, with particular reference to the time of onset of the pathological state during the period in which workers are under health surveillance. it is strongly recommended to provide insurance coverage in situations where the worker is transferred for purely preventive purposes and it is equally important to make a strictly accurate assessment of the relationship of causality between exposure to the pathogenic no ... | 2012 | 3509160 |
| [aids "plague" of the twentieth century]. | 2012 | 3508620 | |
| strong biotype and serotype cross-protective antibacterial and antitoxic immunity in rabbits after cholera infection. | we studied whether immunity evoked by infection with classical or el tor v. cholerae 01 organisms in rabbits (the ritard model) also gives protection against cholera caused by v. cholerae of heterologous biotype as well as serotype, and whether such protection is antibacterial and/or antitoxic. a primary infection with a classical ogawa or el tor inaba strain resulted in intestinal colonization and diarrheal disease in a dose-related manner though the el tor strain was more virulent. as few as 1 ... | 1986 | 3508492 |
| [precapillary arterial pulmonary hypertension and hemorrheologico-coagulation changes]. | 2012 | 3508372 | |
| [chemical properties and biocompatibility of ca(oh)2]. | 1987 | 3507992 | |
| cholera in a pacific island. | 1987 | 3507429 | |
| susceptibility of epididymal boar sperm to cold shock and protective action of phosphatidylcholine. | rapidly cooling (cold shocking) washed cauda boar sperm irreversibly reduced motility and respiration and greatly increased the uptake of 45ca2+; the plasma membranes were removed and the acrosomes detached from nuclei. the motility, respiration, and calcium uptake of the less mature caput sperm were largely unaffected; and there was little damage to the ultrastructure. this indicates that boar sperm becomes less resistant to cold shock as they mature in the epididymis. the oxygen uptake, glucos ... | 1987 | 3507358 |
| susceptibility of epididymal boar sperm to cold shock and protective action of phosphatidylcholine. | rapidly cooling (cold shocking) washed cauda boar sperm irreversibly reduced motility and respiration and greatly increased the uptake of 45ca2+; the plasma membranes were removed and the acrosomes detached from nuclei. the motility, respiration, and calcium uptake of the less mature caput sperm were largely unaffected; and there was little damage to the ultrastructure. this indicates that boar sperm becomes less resistant to cold shock as they mature in the epididymis. the oxygen uptake, glucos ... | 1987 | 3507358 |
| tissue damage in vitamin e deficient rats is not detected by expired ethane and pentane. | despite evidence for tissue damage in vitamin e deficient rats, no discernible difference in ethane and pentane production was apparent compared with controls. it is suggested that other sources of hydrocarbons may mask hydrocarbon production from peroxidation of polyunsaturated fatty acid components of cell membranes, or that tissue damage occurs before peroxidation of the polyunsaturated fatty acids. | 1987 | 3506893 |
| cardiovascular changes during mental stress: correlations with presence of coronary risk factors and cardiovascular disease in physicians and dentists. | stress may play a role in the etiology of cardiovascular disease. research showing that mental stress administered in laboratory settings causes great change in cardiovascular and hemodynamic functioning supports this hypothesis. in a small sample of physicians and dentists, those who showed greater cardiovascular reactivity (hot reactors) to stress were more likely to be hyperlipidemic or to have had a myocardial infarction or coronary bypass surgery. in addition, some of the nonreactive group ... | 2012 | 3506622 |
| [epidemiologic aspects of ovarian carcinoma]. | 2012 | 3505909 | |
| sperm auto-immunity associated with vasectomy, vasovasostomy and epididymovasostomy in korean males. | the prevalence and pattern of circulating antisperm antibodies were assessed in the serum of korean males undergoing vasectomy, vasovasostomy, epididymovasostomy and in a control group of men with normal semen by means of the gelatin agglutination test and the tray agglutination test. sperm-agglutinating antibodies in serum were positive at a titre of 1:32 or greater in 3% of normospermic control males and in 27% of vasectomized men. no significant changes were observed in prevalence of the anti ... | 2012 | 3505829 |
| the opioid system in the restless legs and nocturnal myoclonus syndromes. | 2012 | 3505737 | |
| general practice and the ethics of resource allocation. | 2012 | 3505037 | |
| [sister chromatid exchange and accidental exposure to phenyl-mercury acetate]. | 2012 | 3504672 | |
| [fungal infections in patients with arc with or without aids. evaluation of the chemosensitivity of the isolated strains]. | 2012 | 3504411 | |
| campylobacter diarrhea in an adult mouse model. | an adult mouse (18-20 g) model was developed for studying the pathogenesis of campylobacter isolates. iron-loaded balb/c mice given 10(8)-10(9) campylobacter colony forming units by intraperitoneal injection developed a severe mucoid diarrhea within 4 h. severe diarrhea, consisting of unformed stools containing blood, mucus, and fecal leukocytes, persisted for 24 h. diarrheal symptoms in surviving mice resolved gradually; no diarrhea was observed 5 days after inoculation. mice not pretreated wit ... | 1987 | 3504219 |
| tuberculous meningitis in childhood: clinical and computerized tomography scan manifestations. | 2011 | 3504072 | |
| use and abuse of literary concepts in medicine. | 2012 | 3503156 | |
| clinical supervision for psychiatric nurses. | supervision does not represent merely the acquisition of facts. it is an emotionally charged process that touches on therapists' affective problems, interpersonal conflicts, problems in being helped, and problems in helping (ekstein). as such, it is a process similar to, but not the same as, psychotherapy. supervision is necessary for continued professional growth, no matter how skilled the nurse may be. other mental health disciplines have long accepted supervision as an essential component of ... | 2012 | 3503128 |
| comparative gene mapping: a valuable new tool for mammalian developmental studies. | technological advances in the 1970s encouraged the mapping of homologous gene loci in different mammalian species, including mouse and man. one hundred eighty-five homologous loci have now been mapped in these two species. conservation of linkage is sufficient to identify substantial segments of the two genomes that have been left intact since their divergence from a common ancestor. the recognition of these conserved segments allows experimental manipulation of mouse chromosomes or chromosomal ... | 1987 | 3502975 |
| biphasic effects of epidermal growth factor on bone nodule formation by isolated rat calvaria cells in vitro. | osteoblast-like cells isolated from fetal rat calvaria (rc) form three-dimensional nodules in vitro having the morphological and immunohistochemical characteristics of bone. when administered continually over 21 days of culture, egf caused a dose-related inhibition of nodule formation, as well as a reduction in the proportion of mineralized nodules, at concentrations between 10(-12) to 10(-7) m. the same conditions caused an increase in both cell proliferation and saturation density in the cultu ... | 1987 | 3502681 |
| biphasic effects of epidermal growth factor on bone nodule formation by isolated rat calvaria cells in vitro. | osteoblast-like cells isolated from fetal rat calvaria (rc) form three-dimensional nodules in vitro having the morphological and immunohistochemical characteristics of bone. when administered continually over 21 days of culture, egf caused a dose-related inhibition of nodule formation, as well as a reduction in the proportion of mineralized nodules, at concentrations between 10(-12) to 10(-7) m. the same conditions caused an increase in both cell proliferation and saturation density in the cultu ... | 1987 | 3502681 |
| microelectrode depth study of the electroretinographic oscillatory potentials in the frog retina. | the depth profile of the electroretinographic oscillatory potentials was studied in the isolated frog retina. the intraretinal electrode was introduced from the receptor side, and the reference electrode was placed on the vitreal side. the electroretinogram, recorded either transretinally or with the electrode tip in the receptor layer, showed 4 to 10 oscillatory potential wavelets. as the electrode was advanced proximally, the wavelets disappeared as a function of retinal depth. the wavelets wi ... | 2012 | 3502623 |
| [comparison of the qualities of recovery after anesthesia with propofol, methohexital and etomidate]. | 2012 | 3502320 | |
| [ambulatory anesthesia with propofol in neuroradiology]. | 2012 | 3502317 | |
| [pharmacology of a new anesthetic agent: propofol (diprivan)]. | 2012 | 3502316 | |
| binding of organic acids to surface receptors of lymphocytes as an immunosuppressive mechanism in uremia. | 2012 | 3502315 | |
| common karyotypic pattern in angioimmunoblastic lymphadenopathy with dysproteinemia (aild) and malignant lymphoma of peripheral t-cell origin with aild features. | 2012 | 3502312 | |
| immunophenotypical and molecular genetical examination of angioimmunoblastic lymphadenopathy. | 2012 | 3502311 | |
| analysis of leukemic blast growth factor (lbgf) and autocrine secretion of csf by leukemic blasts. | 2012 | 3502308 | |
| chronic ethanol consumption reduces [3h]inositol (1,4,5) trisphosphate specific binding in mouse cerebellar membrane fragments. | [3h]in(1,4,5)p3 specific binding was determined in membrane fragments from various brain regions of adult male c57/bl mice. [3h]in(1,4,5)p3 specific binding was at least 10 times higher in cerebellum than in either striatum, cerebral cortex, hippocampus, or midbrain. ethanol added in vitro up to 500 mm to cerebellar membrane fragments of control mice had no significant effect on [3h]in(1,4,5)p3 specific binding. in contrast, the maximal number of binding sites (bmax) for [3h]in(1,4,5)p3 was sign ... | 1987 | 3501055 |
| in vitro radiosensitivity of human fresh t-lymphocytes by colony formation assay using pha and recombinant interleukin-2. | 1987 | 3501012 | |
| non-ige-mediated reactions to food: how much is allergic? | 2011 | 3500658 | |
| non-ige-mediated reactions to food: how much is allergic? | 2011 | 3500658 | |
| [two-dimensional representation (bullet) method of thallium-201 myocardial spect; comparison with the polar map]. | 2012 | 3500342 | |
| vaccination against cutaneous leishmaniasis in a murine model. ii. immunologic properties of protective and nonprotective subfractions of soluble promastigote extract. | we have previously demonstrated that balb/c mice can be protected against a fatal infection with leishmania major by i.p. immunization with a soluble leishmanial antigen (sla) preparation in conjunction with the adjuvant, corynebacterium parvum (cp). in this study, sla was separated into nine distinct fractions by anion exchange liquid chromatography, and the fractions were analyzed for their ability to stimulate t cells obtained from immunized mice, to be recognized by vaccine-induced antibodie ... | 1987 | 3499465 |
| estimating health service utilization, immunization coverage, and childhood mortality: a new approach in uganda. | interviews were conducted in the 75 households nearest to each of the 36 rural health facilities in uganda's mbale district in order to estimate childhood morbidity/mortality and the utilization of health services. data were obtained on 2596 children under 5 years of age. there were 50 deaths in the 527 live births in the 12 months preceding the survey, giving an infant mortality rate of 95/1000. there were an additional 51 deaths among the 2069 children 1-4 years of age (25/1000). 34% of deaths ... | 2012 | 3499248 |
| causes of death in diarrhoeal diseases after rehydration therapy: an autopsy study of 140 patients in bangladesh. | the cause of death (besides dehydration) for 140 diarrhoeal patients who died in hospital following rehydration was determined by autopsy examination. children under 5 years comprised 74% of the patients. diarrhoeal pathogens were identified as shigella spp. in 27%, enterotoxigenic escherichia coli in 17%, entamoeba histolytica in 16%, campylobacter jejuni in 12%, salmonella spp. in 4%, vibrio cholerae in 4%, and giardia lambliain 4% of cases. the most frequent underlying causes of death were co ... | 1987 | 3499247 |
| human immunodeficiency virus infection in hemophilia patients: a 4-year prospective study. | 1987 | 3499114 | |
| [gastric teratoma disclosed by neonatal digestive hemorrhage]. | a gastric teratoma diagnosed after a gastro-intestinal tract bleeding in a neonate is reported. the endogastric tumor was shown by gastric endoscopy. the tumor was pediculated and a simple tumorectomy was performed, without trouble later. fifty-three other cases have been found in the literature. most of them presented with abdominal distension and a palpable mass; diagnosis was always made after surgery and the diagnosis of mature gastric teratoma was confirmed by histological examination. thes ... | 2012 | 3498931 |
| [adverse effect of phthivazid in the treatment of children with tuberculosis]. | 2012 | 3498930 | |
| low risk of vertebral fracture in mexican american women. | ethnicity is important in assessing risk for osteoporotic fractures, and should be considered in decision-making about the use of prophylactic treatments. few data are available, however, on fracture risks among hispanic patients. to assess the risk of vertebral fracture in mexican americans, we determined the prevalence of vertebral fracture among 822 patients, aged 15 to 86 years, who underwent spinal roentgenography in a study of low-back pain. after adjusting for age, use of steroids, drug o ... | 2012 | 3498450 |
| difference in monoamine oxidase b activity between c57 black and albino nmri mouse strains may explain differential effects of the neurotoxin mptp. | monoamine oxidase b (mao-b) is the key enzyme in the conversion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(mptp) to n-methyl-4-phenyl-pyridinium ion (mpp+) which causes degeneration of dopaminergic nigral neurons. using a histochemical tetrazolium method for mao-b with tyramine as substrate and chlorgyline for the inhibition of mao-a, black c57 mice were found to have a higher brain mao-b activity than similar aged albino nmri mice. the difference, which was in general density rather than d ... | 1987 | 3498133 |
| effects of stimulus intensity and duration on photoresponses of single rods in the frog retina. | electrical responses to light flashes were recorded from single red rods in dark-adapted retinas of the bullfrog, rana catesbeiana. when the flashes were less than or equal to 50 ms in duration, plots of the peak amplitude of the responses as a function of log stimulus intensity were found to be parallel, and the stimulus intensity and duration required to elicit criterion-amplitude responses showed a linear relation with a negative unit slope. furthermore the waveforms of equal-amplitude respon ... | 2012 | 3498071 |
| the in vivo effects of interleukin 1. i. bone marrow cells are induced to cycle after administration of interleukin 1. | we have previously reported that interleukin 1 (il-1) administration 20 hr before irradiation protects mice from lethal effects of radiation. the recovery of total nucleated bone marrow cells and of hematopoietic progenitor cells was enhanced in il-1 treated, as compared to untreated, irradiated mice. this suggested that il-1 administration may affect the cells in the bone marrow of normal mice. intraperitoneal administration of recombinant il-1 resulted in bone marrow cell enlargement and incre ... | 2012 | 3497980 |
| comparison of sustained-release with standard tiaprofenic acid in the treatment of rheumatic diseases in general practice. | an open, parallel-group study was carried out to compare the efficacy and tolerance of a sustained-release capsule formulation of tiaprofenic acid at a dosage of 600 mg once daily with standard 300 mg tiaprofenic acid tablets given twice daily. four hundred and eighty-five general practice patients with rheumatic disease requiring long-term non-steroidal anti-inflammatory drug therapy were included in the analysis. patients were randomly allocated to receive, in a ratio of 3:1, either 2 x 300 mg ... | 2012 | 3497780 |
| the evaluation of gross hematuria in anticoagulated patients: efficacy of i.v. urography and cystoscopy. | to determine the efficacy of investigating gross hematuria in anticoagulated patients, records were reviewed of 24 patients who had gross hematuria while being treated with warfarin for various thromboembolic disorders. all had iv urography, and half had cystoscopy. sources of bleeding were found in seven (29%) of 24 patients by iv urography and in five (42%) of 12 patients by cystoscopy. abnormalities considered responsible for bleeding included renal stones (four), transitional cell carcinoma ... | 2012 | 3497537 |
| reliability of selective pulmonary arteriography in the diagnosis of pulmonary embolism. | to test the reliability of conventional selective pulmonary arteriography in the diagnosis of pulmonary embolism, three angiographers reviewed the arteriograms of a series of 60 patients retrospectively, independently, and without benefit of additional data. pulmonary arteriograms had been interpreted as positive for pulmonary embolism in 25 of these patients during their hospitalizations. angiographers a, b, and c judged the arteriograms of 24, 29, and 25 patients, respectively, as positive for ... | 2012 | 3497530 |
| trimethoprim used for selective decontamination of the digestive tract in rats: possible route of excretion. | selective elimination of enterobacteriaceae species from the digestive tract of rats has been accomplished by oral treatment with trimethoprim (235 mg/kg body weight/day) within 6 days. in the present study it was investigated whether this elimination was mainly due to antimicrobial activity of trimethoprim excreted with the gastrointestinal mucus or mainly by non-absorbed trimethoprim in the lumen contents. by means of whole gut irrigation (wgi) the lumen contents were washed out, followed by m ... | 1987 | 3497436 |
| [class ii hla antigens and rheumatoid factors in rheumatoid polyarthritis. inverse influence of dr4 and dr7 antigens?]. | a linkage disequilibrium was searched for between hla-dr antigens and rheumatoid factor level both measured using latex agglutination and a solid phase immuno-enzymic assay (fr-pap) among 251 sera from patients suffering from classical rheumatoid arthritis for at least 5 years, recorded in the cooperative swiss study on rheumatoid arthritis. an association between the presence of hla-dr7 and low levels of rheumatoid factor was found. this association was stronger when the dr4, 7 heterozygous sub ... | 2012 | 3497427 |
| t cell subsets in the blast cell population in phytohemagglutinin-stimulated peripheral blood in vitro and in rheumatoid arthritis synovial fluid in vivo. | the immunomodulatory t4/t8 ratio was studied in the total and activated lymphocyte populations by a method combining visualisation of 3h-thymidine incorporating blasts with autoradiography (ar) with simultaneous identification of the respective lymphocyte subsets using monoclonal antibodies in avidin-biotin-peroxidase complex (abc) staining. in rheumatoid arthritis synovial fluid the activated t4/t8 ratio (calculated from t cells in the s phase of the cell cycle) was significantly different from ... | 1987 | 3497421 |
| cerebral hemispheric and contralateral cerebellar hypoperfusion during a transient ischemic attack. | we studied a 79-year-old woman within 3 h of the onset of a motor aphasia and a right hemiparesis. single photon emission computed tomography (spect) showed a 24% decrease in the perfusion of the left middle cerebral artery territory and a 16% reduction in the perfusion of the right cerebellum. a mild naming difficulty was the neurological deficit at the end of the spect examination, and complete recovery was achieved within 24 h. repeated spect study 10 days later was normal. this is the first ... | 2012 | 3497164 |
| inhibitors of protein kinase c block activation of b lymphocytes by bacterial lipopolysaccharide. | activation of murine splenic b lymphocytes (b cells) by bacterial lipopolysaccharide (lps) was found to be markedly inhibited by 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (h-7) and n-[2-(methylamino)ethyl]-5-isoquinolinesulfonamide (h-8), two potent inhibitors of protein kinases. the higher sensitivity of dna synthesis, rna synthesis and protein n-glycosylation activity to h-7, relative to h-8, strongly supports the proposal that protein kinase c plays a critical role in the activation of b ... | 2012 | 3496881 |
| local treatment with epurox (superoxide dismutase and catalase of human origin) in the chronic inflammatory and degenerative rheumatism. | 1986 | 3496868 | |
| determination of t lymphocyte subpopulations in patients with lung cancer. a comparison between lung lavage and peripheral blood by monoclonal antibodies and flow cytometry. | in order to determine whether the alterations of immunoregulatory t cells described both in smokers and in patients with lung cancer occur in the deep lung as well as in peripheral blood, we analyzed t lymphocyte subpopulations in bronchoalveolar lavage (bal) and in the blood of 12 patients with untreated lung cancer and of 8 controls. the immunocompetent cellular population of bal fluid analyzed by differential cell count of alveolar macrophages, lymphocytes and neutrophils did not show conside ... | 2012 | 3496638 |
| evaluation and treatment of diabetic foot problems. | 2012 | 3495728 | |
| [lymphocyte cytotoxicity against autologous tumor cells and the effect of interferon-beta on their activities. (1) evaluation by modification of target tumor cells]. | ifn is known to enhance nk activity against cultured cell lines such as k562, but not against frozen autologous tumor cells. in order to obtain increased nk cytotoxicity using ifn-beta, various modifications were performed on autologous tumor cells. ifn-beta induced more enhanced nk cytotoxicity of normal lymphocytes when frozen tumor target cells were cultured for 4-5 days in the medium, or when these cells were treated with vibrio cholerae neuraminidase (vcn). however, in an autologous setting ... | 1987 | 3495240 |
| graft disease in coronary artery bypass patients. | 2012 | 3494889 | |
| human t hybridoma-derived immunoglobulin-binding factors. | a human t hybridoma was generated lacking demonstrable low-affinity ige surface receptors. this cell line produces spontaneously immunoglobulin-binding factors. the factors have an affinity for human ige and igg as well as for igg from other species. the binding factors were purified by concanavalin a affinity chromatography, an ige immunoaffinity column and sds-page. this purification procedure resulted in five major proteins bands at 13, 15, 30, 60 and less than 150 kilodaltons. as judged by w ... | 1987 | 3494683 |
| endothelial viral inclusions in fuchs' corneal dystrophy. | a case of fuchs' corneal dystrophy is presented. the patient, a 70-year-old white woman, had bilateral decreasing vision, especially while reading and driving at night. clinical features were characteristic of fuchs' corneal dystrophy. ultrastructural studies demonstrated findings in descemet's membrane typical of those previously reported with numerous tactoids of fibrous long-spacing collagen in the posterior collagenous layer and in the guttata. in the endothelial cells were encapsulated elli ... | 2012 | 3493969 |
| new approaches for the analysis of mast cell maturation, heterogeneity, and function. | mast cells are regarded as potentially critical participants in a wide variety of important biological processes. yet it has been difficult to ascertain the precise contribution of mast cells to many of these reactions. in part, this reflects recognition that different populations of mast cells may vary in phenotype and therefore may express different functions. another problem has been the lack of suitable model systems for identifying and quantitating the mast cell's unique roles in biological ... | 1987 | 3493923 |
| remote metabolic effects of cerebrovascular lesions: magnetic resonance and positron tomography imaging. | combined positron emission tomography (pet) and proton magnetic resonance imaging (mri) study were performed in six patients with chronic supratentorial stroke to investigate whether remote hypometabolic regions revealed by pet showed any abnormality on mri. either regional oxygen consumption (n = 4) or glucose utilization (n = 2) were measured using pet and the 15o steady state 18fdg technique, respectively. four patients, with deeply located brain lesions, showed a significant metabolic reduct ... | 2012 | 3493445 |