Publications

trace amounts of ganglioside gm1 in human milk inhibit enterotoxins from vibrio cholerae and escherichia coli.	gangliosides were isolated from human milk fat and purified by silica gel column chromatography and high performance liquid chromatography (hplc). low amounts of the ganglioside gm1, detected by high performance thin layer chromatography (hptlc)-immunoassay, were found in all fractions with enterotoxin-inhibitory activity, while fractions without gm1 were inactive. it is concluded that gm1 is responsible for enterotoxin-inhibitory activity in the ganglioside fraction from human milk.	1987	3540506
b subunit-whole cell and whole cell-only oral vaccines against cholera: studies on reactogenicity and immunogenicity.	we conducted a randomized trial among persons in rural bangladesh to evaluate the side effects and immunogenicity of orally administered b subunit-killed whole cell (bs-wc) and killed whole cell-only (wc) cholera vaccines and a killed escherichia coli strain k12 placebo proposed for field testing. three doses of bs-wc, wc, e. coli, or a control agent were given with antacid to 1,257 women (aged greater than 15 years) and children (aged to to 15 years). the four groups exhibited no statistically ...	1987	3540139
changes in the concentration of the calcium-binding parvalbumin in cross-reinnervated rat muscles. comparison of biochemical with physiological and histochemical parameters.	the fast extensor digitorum longus (edl) and the slow soleus (sol) muscles were cross-reinnervated in both directions in the rat. during the following transformation of muscle type properties, the expression of the ca2+-binding parvalbumin (parvalbumin, mr = 12,000) was investigated. the combined biochemical, histochemical, and physiological results demonstrated that the amount of parvalbumin decreased in the fast to slow (x-edl) and increased in the slow to fast (x-sol) transformation. alterati ...	1987	3539938
perioperative stroke: the noncardiac surgery patient.	this chapter reviewed the mechanisms and manifestations of transient and irreversible cerebral ischemia and the current experimental approaches to attenuate ischemic neuronal injury. patients with signs or symptoms of cerebral ischemia are likely to have abnormal cerebrovascular dynamics, with areas of cerebrum at risk, and may be at an increased risk of stroke after general or vascular surgery. such patients also have a very high frequency of associated cardiac disease. in this chapter, guideli ...	2011	3539814
assay dependent specificities of monoclonal antibodies to bacterial antigens.	six rat monoclonal antibodies, all of the igg2b class, were generated from rats immunized with the 35a3 (inaba) and nih-41 (ogawa) strain of vibrio cholerae and selected by enzyme-linked immunosorbent assay (elisa) on the whole organisms. when the fine specificity was dissected by several different immunological assays, the antibodies could be divided into three groups, each with a different specificity profile. two antibodies were totally specific to the ogawa serotype on all assays, three had ...	1986	3539429
the concurrent associations of group a streptococcal serotypes in children with acute rheumatic fever or pharyngitis-associated glomerulonephritis and their families in kuwait.	a group of 146 children with acute rheumatic fever and 256 members from their families, and a group of 125 children with post-streptococcal glomerulonephritis and 199 family members, together with a group of 145 children with non-complicated group a streptococcal pharyngitis were examined over a period of three years. the purpose of the study was to explore the concurrent association and distribution of group a streptococcal serotypes among the three groups. strains isolated from the children wi ...	1986	3538720
[clinical incidence of subclavian thromboses following pacemaker implantation].	although pacemaker (pm) implantation has developed into a standard therapy in appropriate rhythm disorders the procedure is not free of complications. one of the most common problems is thrombotic alteration in the region of the entry of the pacemaker electrode into the venous system. to obtain more details of the incidence and extent of these complications, we investigated a total of 97 patients in two groups, clinically, phlebographically and by doppler-ultrasound technique. 56 (30 males, 26 f ...	2013	3538687
[remote results of the treatment of lupus nephritis].		2012	3538598
body fat: what is regulated?	this paper assumes that body fat is regulated and then reviews our ignorance about how this is accomplished. it concentrates on the challenge posed by site differences between different depots, and discusses a variety of experimental approaches that may be helpful.	2012	3538074
[the basic bolus principle of insulin therapy. renaissance of an old treatment concept].		2012	3537659
studies on the mechanics of the normal human middle ear.	the middle ear was studied in temporal bone preparations using a laser-doppler interferometer. for measurements at a sound level of 80 db spl this method proved to be very reliable, as was shown by good reproducibility of results in experiments over more than 6 hours. the vibrations of the tympanic membrane and stapes footplate were studied from 200 hz to 10 khz and the results demonstrate a piston-like movement of the stapes footplate up to 120 db spl. the damping effect of the normal ear is lo ...	1986	3536194
sp1--really a tumor marker for lymphoid malignancy?		2013	3536176
cardiopulmonary resuscitation with interposed abdominal compression.	the addition of interposed abdominal compressions (iacs) to otherwise standard cpr enhances artificial circulation both in anesthetized dogs with ventricular fibrillation and in electrical models of the circulation that demonstrate fundamental mechanisms generating flow. manual abdominal compressions cause both central aortic and central venous pressure pulses but, because of differences in venous and arterial capacitance, the former are usually greater than the latter. thus mean perfusion press ...	1986	3536164
intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging.	a study in vitro of specimens of human aortic and common carotid arteries was carried out to determine the feasibility of direct measurement (i.e., not from residual lumen) of arterial wall thickness with b mode real-time imaging. measurements in vivo by the same technique were also obtained from common carotid arteries of 10 young normal male subjects. aortic samples were classified as class a (relatively normal) or class b (with one or more atherosclerotic plaques). in all class a and 85% of c ...	1986	3536154
eagle's syndrome: review of the literature and implications in craniomandibular disorders.		2013	3536135
[decreased activity of the renal vasodilation and natriuretic system in normotensive men with a familial history of essential hypertension and decreased na+, k+-cotransport in erythrocytes].		2013	3536113
right ventricular function: the assessment of contractile performance.		2013	3536105
tah: a bridge to transplant.		2013	3536073
age-related physiologic and pathologic changes affecting lower urinary tract function.	the physiologic changes and pathologic conditions that are frequently seen in the elderly population create a clinical challenge requiring knowledge of the "normal" voiding function, as well as commonly observed alterations. this article reviews the more common physiologic changes, disease states, and iatrogenic causes associated with aging that affect urinary tract function.	2012	3536058
the sapphire crystal infrared photocoagulator and polyglactin (vicryl) mesh: two new alternatives to the suturing of radial nephrotomies.	the sapphire crystal infrared photocoagulator and polyglactin (vicryl) mesh, two new methods for closure of radial nephrotomies, were assessed in 16 dogs. six radial nephrotomies were carried out in each dog; in 10 the nephrotomies were sealed by the infrared photocoagulator and in six they were left open, but the kidney was covered with a polyglactin mesh. functional and morphological studies were performed using creatinine clearance, microfil casting, corrosion cast angiography and histology. ...	1986	3535988
interleukin-1 (22-k factor) induces release of granulocyte-macrophage colony-stimulating activity from human mononuclear phagocytes.	an electrophoretically pure preparation of natural human interleukin-1 (il-1) was shown to stimulate in vitro colony formation in human bone marrow cultures. day 4 myeloid cluster-forming cells (cfc), as well as early (day 7) and late (day 10) granulocyte-macrophage colony-forming units (cfu-gm) were stimulated in a dose-dependent fashion. at optimal concentrations of il-1, the number of day 4 cfc reached 72%, the number of day 7 cfu-gm reached 32%, and the number of day 10 cfu-gm reached 80% of ...	1986	3535928
double-blind controlled trial to compare anti-inflammatory effects of tolmetin 2%, prednisolone 0.5%, and placebo in post-cataract extraction eyes.	this paper compares the efficacy of tolmetin, prednisolone, and placebo (vehicle only) in controlling post-cataract extraction inflammation in a double-blind trial involving 120 patients. seventeen patients were excluded from analysis. the results of the 103 patients analysed showed that 94% of the prednisolone treated group was judged to have been successfully treated as compared with 53% of the tolmetin treated group and 46% of the vehicle treated group. the differences between the prednisolon ...	2012	3535872
the sky and tomorrow.	as a member of the "fifty-year" air force research and development club himself, the author first takes a "snap-shot" look at the environment surrounding this activity for each 5-year interval--from 1936 to the present, and into the future--and discusses the impact of the changes. then, seven principal areas--technology, materials, vehicles and control, propulsion, electronics, weapons environment, and man--are discussed with respect to the timing and extent of their impact upon the air force, l ...	1986	3535784
digitalis--two hundred years.		2012	3535394
effect of motion on the sonographic and magnetic resonance patterns of ageing blood.	the sonographic appearance of a hematoma may be affected by various factors, including the age of the hematoma. the effect of mechanical motion on the echogenicity and histologic appearance, and on the proton relaxation times t1 and t2 of blood clots, was studied in vitro for up to 21 days. all clots were of similar echogenicity and microscopic appearance during the first 2 days. the minimally disturbed clots were sonolucent from day 4 onwards, whereas moderate mechanical disturbance changed the ...	1986	3535388
alternative major connectors for mandibular partial dentures.		2012	3534974
[technics and results of autografts in surgery of pterygium. study based on 34 grafts].	the first procedure consists of corneal autograft sampled at noon or six o'clock on the pterygium's excision bed, combined to a conjunctival flaps translation. the second technique consists of a monoblock corneoconjunctival graft with a limbic hinge. the operative difficulties, post-surgical complications and results are discussed. the results seem very promising: one recurring case out of 34 grafts performed. the recurring risk, more acute in tropical environment where it is frequently impossib ...	2012	3534065
nutrition in american indian health: past, present, and future.	in addition to benefiting from public health programs for all americans, american indians and alaska natives are eligible for health services from the indian health service (ihs), u.s. public health service. indian health service provides comprehensive health services, including nutrition and dietetics, to american indians and alaska natives living on or near federal indian reservations or in traditional indian territory, such as oklahoma and alaska. dramatic improvements have occurred in the he ...	2012	3534063
gm1 erythroimmunoassay for detection and titration of escherichia coli heat-labile enterotoxin.	a gm1 ganglioside erythroimmunoassay for the detection of heat-labile escherichia coli enterotoxin (lt) was developed for use in poorly equipped laboratories in developing countries. this assay is based on the immunological similarity between vibrio cholerae toxin and lt and uses cholera toxin antiserum and sheep anti-rabbit immunoglobulin covalently coupled to sheep erythrocytes as conjugate. this assay has the following advantages over other currently available techniques: the reagents it uses ...	1986	3533985
enzyme immunoassay for detection of salmonella in foods: collaborative study.	a collaborative study was performed in 25 laboratories to validate an enzyme immunoassay (eia) procedure utilizing 2 specific monoclonal antibodies for rapid detection of salmonella in foods. the eia was compared with the standard culture procedure for detection of salmonella in 6 food types: ground black pepper, soy isolate, dried whole eggs, milk chocolate, nonfat dry milk, and raw deboned turkey. uninoculated and inoculated samples were included in each food group analyzed, with the exception ...	1986	3533896
prosthodontic considerations for patients with cleft lip and palate.	the prosthodontist provides the final active treatment for the patient with a cleft. he must anticipate and decide upon the prosthodontic procedures in collaboration with the plastic surgeon and/or the orthodontist during the period of their interventions. the purpose of prosthodontic treatment is to prevent the relapse of the maxillary segments and the teeth after surgical and/or orthodontic correction, as well as the rehabilitation of mastication, speech and aesthetics. the individual peculiar ...	2012	3533786
studies on the genetic and cellular control of sensitivity to enterotoxins in the sealed adult mouse model.	a sealed adult mouse (sam) model was developed for studies on the effects of cholera enterotoxin (ct). with this system, 38 strains of outbred, inbred, congenic, recombinant, and mutant mice were starved for 24 h, anorectally occluded with cyanoacrylamide ester glue, given ct per os, and sacrificed at 6 h. fluid accumulation (fa) values were calculated as gut weight to body weight ratios. at a saturating dose of ct (24 micrograms per mouse), fa responses were found to be independent of body weig ...	1986	3533783
[sem study of the cervical margins in composite restorations using bonding agents].		2012	3533512
[composite resins--new fillers, curing technology and dentin adhesive agents].		1986	3533511
[crowns with vestibular shoulders in porcelain].		2012	3533110
further acquisitions on gonadal function in bromocriptine treated hyperprolactinemic male patients.	the diurnal variation of plasma total and free testosterone (tt and ft) and the gonadotropinemic response to lh-rh were evaluated in a group of hyperprolactinemic impotent males with pituitary microprolactinoma before and during therapy with bromocriptine, a well known dopamine agonist drug. before treatment, basal levels not only of tt but also of ft were decreased and the diurnal variation of both tt and ft was absent. moreover, the lh-rh test showed a delay in the lh response peak, together w ...	2012	3532137
[dispersion injection needle for insulin administration].	a new dispersion syringe needle is proposed to administrate insulin to diabetics. it features side location of injection holes 4-8 of which are arranged along the needle body. the needle so designed provides greater absorption area, thus increasing absorption rate and reducing insulin decay in the subcutaneous layer. with the needle, more effective insulin action to compensate glucose content is achieved as compared to the conventional design.	2012	3531757
photoelastic analysis of stresses in resin-bonded cingulum rest seats.	two-dimensional photoelastic analysis of resin-bonded cingulum rest seats demonstrated improvement in stress distribution when the lingual surface of the tooth was prepared with a cingulum groove. this preparation is more important for teeth that are more vertically or lingually oriented and have flatter lingual surfaces, such as mandibular canines.	2012	3531487
the effect of once-daily minoxidil on blood pressure and plasma lipids.	once-daily minoxidil administration was added to the treatment regimen of 11 patients with hypertension that was inadequately controlled by nadolol 160 mg and chlorthalidone 50 mg given once daily. additional diuretic therapy was needed by five patients. during treatment without minoxidil and at three and six months of maintenance minoxidil therapy, respectively, 24-hour postdose supine blood pressure fell significantly (p less than .01) from 142 +/- 19/96 +/- 6 mm hg to 132 +/- 16/87 +/- 4 and ...	2012	3531249
endogenous digitalis-like immunoreactive substances in cord serum characterized by anti-digitoxin and anti-digoxin antibodies. effect of modulated incubation conditions.	digoxin-like immunoreactive substances (dlis) have been extensively described in biological fluids of pregnant women, neonates and renal impaired patients, by the use of several digoxin immunoassays. in this paper a similar interference with anti-digitoxin antibodies is reported by investigating 20 cord sera. by increasing both the time and the temperature of the incubation, the levels of digitalis-like immunoreactive substances may be modulated and decreased to zero. digitoxin- and digoxin-like ...	2012	3530526
fetal epithelial binding of 1,2-dibromoethane in mice.	whole-body autoradiography and computer-assisted image analysis were used to study the tissue binding of the volatile carcinogenic pesticide 1,2-dibromo[14c]ethane (dbe) in c57bl mouse fetuses. autoradiograms obtained from pregnant mice in late gestation (day 16-17), showed a high level of non-volatile metabolites in the epithelia of the fetal upper alimentary tract and respiratory tract. as determined by image analysis, the concentration of non-extractable (presumably covalently bound) metaboli ...	1986	3530523
selectivity properties of pores induced in host erythrocyte membrane by plasmodium falciparum. effect of parasite maturation.	the intraerythrocytic malarial parasite permeabilizes its host cell membrane by inducing pore-like pathways which mediate the passage of nonelectrolytes and anions. in the present work we show that, although the permeability increases with parasite maturation, the selectivity of the pores to various solutes is essentially preserved, suggesting that the number of pores increases without any alteration in their intrinsic solute conductance.	1986	3530325
accurate ultrasonic estimation of fetal weight. prospective analysis of new ultrasonic formulas.	five new ultrasonic weight formulae incorporating head circumference, fetal femur length, and a correction for oligohydramnios were prospectively analyzed in a group of 198 unselected patients scanned within 72 hours of birth. comparison with the shepard formula showed that inclusion of these parameters slightly, but significantly, improved the random error of weight estimation. the best-fit formula was: log(10) bw = .04355hc + .05394ac - .0008582hc x ac + 1.2594 (fl/ac) - 2.0661.	2011	3530267
[2-cycle culture of vibrio cholerae in a fermenter].	the method for the two-cycle cultivation of v. cholerae, reference strains inaba and ogawa, in a fermenter has been developed. in the first and second cultivation cycles no difference in the yield of the biomass and in the ultrastructure of the vibrios has been established. in the second cycle a decrease in the minimum time of generation has been observed. the vaccines obtained in the first and second cultivation cycles have not been found to differ in their antigenic and immunogenic activity. t ...	1986	3529759
codes of medical ethics: traditional foundations and contemporary practice.	the hippocratic coprus recognized the interaction of 'business' and patient-health moral considerations, and urged that the former be subordinated to the latter. during the 1800s with the growth of complexity in both scientific knowledge and the organization of health services, the medical ethical codes addressed themselves to elaborate rules of conduct to be followed by the members of the newly emerging national medical associations. after world war ii the world medical association was establis ...	2012	3529416
age-related changes in tissue metabolic rates and sensitivity to insulin in the chicken.	in vitro metabolic studies were conducted with tissues from broiler pullets at 4, 8, and 12 weeks of age. in order to accurately assess plasma insulin at each of these ages, blood samples were withdrawn via indwelling venous catheters at 30-min intervals for 6 hr, and plasma was assayed by a homologous chicken insulin (cins) radioimmunoassay. birds (n = 6) were sacrificed 24 hr following blood sampling and livers, hearts, and abdominal fat pads removed for metabolic studies. tissue slices of rem ...	1986	3529070
[functioning of the aging heart].		2012	3529060
[urinary excretion of beta 2 microglobulin in workers chronically exposed to various heavy metals].	increased urinary excretion of beta-2-microglobulin (b2m) is regarded as one of the earliest indices of the lesion of renal tubules. a great usefulness of the determination of this protein has been demonstrated in workers chronically exposed to heavy metals. the investigations have been carried out in 79 workers chronically exposed to cadmium, 39 workers chronically exposed to mercury and 31 non-exposed subjects. the urinary b2m concentration in all subjects was determined using the radioimmunoa ...	2012	3528739
saliva, breast milk, and serum antibody responses as indirect measures of intestinal immunity after oral cholera vaccination or natural disease.	the possibility that antibody responses in serum, saliva, or breast milk samples to oral vaccines or enteric infections may reflect the intestinal immune response was evaluated in bangladeshi volunteers orally immunized with a cholera b subunit-whole-cell vaccine (b + wcv) and in patients convalescing from enterotoxin-induced diarrheal disease. two peroral doses of b + wcv induced antitoxin and antibacterial antibody responses in the intestinal fluids of 76 and 92%, respectively, of the voluntee ...	1986	3528211
the clinical use of alkaline phosphatase enzymes.	the enzyme alkaline phosphatase is an important serum analyte and its elevation in serum is correlated with the pressure of bone, liver, and other diseases. the analysis of the isoenzymes of alkaline phosphatase is an aid in diagnosing liver and/or bone disease, especially the high molecular weight isoenzymes that appear in cholestatic liver disease.	2012	3527542
cholera.		1986	3527493
[nursing care in the treatment of parkinson's disease by encephalon-stereotactic surgery].		2012	3527457
common hair disorders.		2012	3527127
contact dermatitis.		2008	3527125
drinking behavior of high risk college men: contradictory preliminary findings.	seventeen high risk and seventeen low risk college-aged men were compared with respect to drinking behavior/problems and certain implicated personality characteristics. the low risk subjects were, surprisingly, found to drink and become intoxicated more frequently than high risk subjects. they also reported significantly higher sensation seeking scores. this latter variable accounted for the greatest amount of variance in both risk status and frequency of drinking. by contrast, high risk subject ...	2012	3526955
oral cancer detection. the importance of routine screening for prolongation of survival.	the incidence of oral cancer has increased in the past ten years. early diagnosis and treatment are essential to long-term survival; however, patients at highest risk visit the dentist infrequently. the reddish, velvety or erythroplakial lesion at the base of the tongue or floor of the mouth is highly suspicious in any patient and requires further evaluation. high-risk patients with less suspicious appearing lesions must be reevaluated on close recall. prognosis improves vastly when the lesion i ...	2012	3526308
preparation of capped rna transcripts using t7 rna polymerase.		1986	3526287
enhanced responses to pressor stimuli by intracerebroventricular infusions of angiotensin ii in conscious rats.	effects of the intracerebroventricular (ivt) infusion of a subpressor dose (3 ng/kg/min) of angiotensin ii (ang ii) on the pressor responses to intravenous (iv) infusions of ang ii and to iv bolus injections of norepinephrine (ne) were studied in conscious rats. this study was undertaken to determine whether activations of the brain renin-angiotensin system alter pressor responsiveness to iv infusions of ang ii and iv injections of ne in the conscious state. pressor responses to iv infusions of ...	1986	3525881
multiple hormone storage by 'polycrine' cells in the pancreas (from a case of nesidioblastosis).	pancreatic tissue from a case of neonatal hypoglycaemia with nesidioblastosis has been studied by routine light and electron microscope techniques and by highly sensitive light and electron microscope immunolocalization methods. a hyperplastic nodule within the pancreas from this case contained enlarged distorted haemorrhagic islets, with a variable rim of exocrine tissue. islet cells in these areas were shown to contain more than one hormone in separate granules. an immunoperoxidase system usin ...	2010	3525469
mechanism and significance of insulin resistance in myotonic dystrophy.	in order to elucidate the mechanism of the glucose intolerance frequently associated with myotonic dystrophy (md), glucose metabolism of 10 patients and 10 controls was investigated using the following tests: successive intravenous stimulation of insulin secretion by glucose and tolbutamide, detection of serum islet cell antibodies, measure of the specific insulin binding on erythrocytes and evaluation in vivo of insulin sensitivity by the euglycaemic glucose clamp method. glucose tolerance was ...	2003	3525363
mechanism and significance of insulin resistance in myotonic dystrophy.	in order to elucidate the mechanism of the glucose intolerance frequently associated with myotonic dystrophy (md), glucose metabolism of 10 patients and 10 controls was investigated using the following tests: successive intravenous stimulation of insulin secretion by glucose and tolbutamide, detection of serum islet cell antibodies, measure of the specific insulin binding on erythrocytes and evaluation in vivo of insulin sensitivity by the euglycaemic glucose clamp method. glucose tolerance was ...	2003	3525363
protein-chemical analysis of pertussis toxin reveals homology between the subunits s2 and s3, between s1 and the a chains of enterotoxins of vibrio cholerae and escherichia coli and identifies s2 as the haptoglobin-binding subunit.	the purified toxin of bordetella pertussis was dissociated in 5 m urea in the presence of immobilized haptoglobin. the toxin was dissociated in free s1, free s5 and the free complexes s2-s4 and s3-s4, with s2-s4 as the only haptoglobin-binding moiety, identifying s2 as the haptoglobin-binding protein. partial nh2-terminal amino acid sequences were obtained from the dissimilar toxin subunits, after separation by sds-polyacrylamide gel electrophoresis followed by electroblotting onto polybrene-coa ...	1986	3525228
oral biopsy technique. the pathologist's perspective.		2012	3524767
midbrain lesions, dopamine and male sexual behavior.	destruction of the medial preoptic area (mpoa) eliminates mating in male rats and this region is believed to play a major role in the control of male sexual behavior. efferents from the mpoa pass through and/or terminate in 4 midbrain regions: the dorsolateral tegmentum (dlt), the central gray, and the a9 and a10 areas. the present study reports the effects of bilateral destruction of each of these midbrain regions on brain catecholamines and sexual behavior in male rats. dlt lesions eliminated ...	1986	3524604
blood glucose control and diabetic complications.	two hypotheses have been advanced to explain the appearance of microvascular complications in diabetic patients with glycemic control. the genetic hypothesis suggests that the development of diabetic complications is genetically determined and independent of diabetic control, whereas the metabolic hypothesis suggests that long-term hyperglycemia causes the subsequent development of small-blood-vessel complications. we review data that either support or reject these hypotheses and suggest a third ...	2012	3524339
mononuclear cell factor modulates the concomitant release of proteoglycan and latent proteinase by human articular cartilage in organ culture.		1986	3524149
an appreciation of dewitt stetten, jr.		2012	3524133
[surgical methods of restoring the palatopharyngeal closure following unsuccessful uranoplasty outcomes].		2012	3523845
selective primary health care. xxiv. malaria.	the eradication of malaria remains an elusive goal in many tropical and subtropical countries, even though methods are available that, if used correctly, will permit control of the disease in most area. these methods include chemotherapy directed against the parasite in the human host and such antivector techniques as a reduction of mosquito breeding sites and an attack on the aquatic and adult stages of mosquitoes. the direction of a malaria control program requires a detailed understanding of ...	1986	3523703
old and new aspects of megakaryocyte development and function.		2012	3523519
isolated hypoaldosteronism and abnormalities in renin, kallikrein, and prostaglandin.	to further define the pathophysiology of the syndrome of acquired isolated hypoaldosteronism, we determined plasma concentrations of active and inactive renin and urinary kallikrein and prostaglandin e2 excretion rates in 11 patients with the syndrome, 12 patients with similar serum creatinine levels, but without hyperkalemia, and in 12 normotensive patients with normal renal function and low plasma renin activities (pra). ten of 11 patients with the syndrome had low baseline pra, and, unlike th ...	2012	3523269
[bibliographic survey. the irvine-gass syndrome].		2012	3522719
isolation and characterization of the vibrio cholerae reca gene.	a 3.6-kilobase psti fragment was isolated from a vibrio cholerae chromosomal dna library and shown to encode reca-like activity in complementation studies with escherichia coli reca mutants. although dna hybridization experiments failed to detect any homology between the e. coli and v. cholerae reca genes, hyperimmune antiserum produced against purified e. coli reca protein recognized epitopes shared by the v. cholerae protein. the v. cholerae chromosomal fragments, when cloned and transferred t ...	1986	3522553
prevalence of bronchial hyperresponsiveness in highly trained athletes.	previous studies indicated that the prevalence of symptomatic asthma is about 4 to 7 percent. no similar studies exist to suggest the prevalence of asthma in highly trained competitive athletes, since asthma is thought to be an uncommon disease in this population. we became concerned, therefore, when a large number of football players developed symptoms consistent with asthma during preparation in california for the rose bowl in december 1981. we studied the team and found 12 percent of the foot ...	2012	3522119
does murcs association represent an actual nonrandom complex of malformations?	the murcs association was first suggested by duncan in 1979 as a distinctive nonrandom association of congenital anomalies involving the mullerian duct, the kidneys and the cervicothoracic spine. two personal cases, highly resembling duncan's description, are reported. in our opinion, they seem to support somehow the hypothesis that murcs association should be considered as an autonomous pathological entity. the great phenotypical variability and the still unknown etiopathogenetic mechanism are ...	2012	3522046
influence of cadaver donor age on renal graft survival.	it has been suggested that kidneys from young and old donors do less well after transplantation. we have studied this problem in a retrospective analysis of all cadaveric transplants performed in our center during the last 10 years. all patients were followed for at least six months. recipients younger than 16 years were excluded from this analysis. thirty-six patients received a kidney from a donor younger than 11 years (group a), 374 received a kidney from a donor aged between 11 and 51 years ...	2012	3521999
more on eponyms used in anesthesiology.		2012	3521395
drug antibody measurement by homogeneous enzyme immunoassay with amperometric detection.		2012	3521389
otosclerosis 1981 to 1985. our four-year review and current perspective.		2012	3521305
correction of the inverted nipple.	a simple procedure for correction of inverted nipples is described. the key to the method is the preparation of 2 deepithelized dermal flaps after supplementing the volume of tissue beneath the nipple, and preventing recurrence of the deformity with slings.	2012	3521233
flow distribution between the endocrine and exocrine parts of the isolated rat pancreas during perfusion in vitro with different glucose concentrations.	previous studies in our laboratory have indicated that pancreatic islet blood flow is stimulated by glucose. in an attempt to evaluate to what extent intrapancreatic control mechanisms are involved in the glucose modulation of islet blood flow the distribution of flow between the endocrine and exocrine parts of the rat pancreas during perfusion in vitro with different glucose concentrations have now been studied. for this purpose pancreatic glands from 29 rats were perfused at a flow rate of 1.5 ...	1986	3521204
[discussion of various pathological cases during the sessions of the wilno medical society headed by prof. jedrzej sniadecki].		2012	3521102
[characteristics of the organization of cell proliferation in plants in relation to the problem of stem cells].	cellular patterns of continual cell proliferation are considered in plants and animals. in plants, the cells, analogous to the animal stem cells, can be formed many times during plant ontogenesis. their functioning as stem cells is determined by their position in the growing organ. this is the reason why a plant can grow for a very long time. there are some common features of cellular patterns of proliferation in plants and animals providing the stability and optimal subordination between cell p ...	2012	3521007
[enterotoxins produced by enterotoxigenic escherichia coli].		1986	3520679
[determining cardiac output by rheographic methods in thoracic surgery].		2013	3520543
the trfb region of broad host range plasmid rk2: the nucleotide sequence reveals incc and key regulatory gene trfb/kora/kord as overlapping genes.	we report the nucleotide sequence of the trfb region of broad host range plasmid rk2. this region encodes the following loci: trfb, identical to kora and kord, which encodes a key transcriptional repressor of certain rk2 operons; incc, which appears to be involved in plasmid maintenance, possibley through post-transcriptional regulation of trfa product levels; the start of korb, which encodes a second transcriptional repressor of operons involved in stable inheritance of rk2. these loci are expr ...	1986	3520485
inspissated bile in a neonate with cystic fibrosis.		2013	3520008
presence of hemagglutinin/protease and other potential virulence factors in o1 and non-o1 vibrio cholerae.		1986	3519790
effect of neutralization of gastric acid on immune responses to an oral b subunit, killed whole-cell cholera vaccine.		1986	3519789
immunocytochemical localization of cathepsin b in rat kidney. ii. electron microscopic study using the protein a-gold technique.	thin sections of lowicryl k4m-embedded materials were labeled with protein a-gold complex. gold particles representing the antigen sites for cathepsin b were exclusively confined to lysosomes of each segment of the nephron. the heaviest labeling was noted in the lysosomes of the s1 segment of the proximal tubules. labeling intensity varied considerably with the individual lysosomes. lysosomes of the other tubular segments, such as the s2 and s3 segments of the proximal tubules, distal convoluted ...	1986	3519753
defective suppression by insulin of leucine-carbon appearance and oxidation in type 1, insulin-dependent diabetes mellitus. evidence for insulin resistance involving glucose and amino acid metabolism.	to determine whether a resistance to insulin in type 1, insulin-dependent diabetes mellitus (iddm) is extended to both glucose and amino acid metabolism, six normal subjects and five patients with iddm, maintained in euglycemia with intravenous insulin administration, were infused with l-[4,5-3h]leucine (leu) and [1-14c]alpha ketoisocaproate (kic). steady-state rates of leucine-carbon appearance derived from protein breakdown (leu + kic ra) and kic (approximately leucine) oxidation were determin ...	2012	3519679
guanidine hydrochloride denaturation studies of mutant forms of staphylococcal nuclease.	several mutant forms of staphylococcal nuclease with one or two defined amino acid substitutions have been purified, and the effects of the altered amino acid sequence on the stability of the folded conformation have been analyzed by guanidine hydrochloride denaturation. two nuc- mutations, which greatly reduced the level of enzyme activity accumulated in e coli colonies carrying a recombinant plasmid with the mutant nuc gene (ie, a nuc- phenotype), both result in protein unfolding at significan ...	1986	3519625
metabolic rhythms in adolescents with diabetes during treatment with porcine or human insulin.	metabolic rhythms were studied over 24 hours in eight adolescent diabetic patients during treatment with porcine insulin and after transfer to human insulin. despite an increase in dose with human insulin no significant changes were found in fasting blood glucose, 24h mean blood glucose, or glycosylated haemoglobin concentrations. significantly higher 24h mean blood lactate concentrations and lower total ketone bodies and glycerol concentrations were observed during treatment with human insulin. ...	1986	3518640
is unilateral electroconvulsive therapy really the treatment of choice in endogenous depression?		2012	3518574
[epidural anesthesia during labor: comparison of 3 combinations of fentanyl-bupivacaine and bupivacaine alone].	the association of bupivacaine and fentanyl appeared as the best method of inducing satisfactory obstetrical analgesia. but the various techniques of drug administration had to be detailed; this justified the present work, a single-blind controlled trial performed on 159 primipara women at term (except one of them), randomized in four groups, after informed consent. in each group, the number of patients, the age and the degree of uterine dilatation at the beginning of the epidural anaesthesia we ...	2012	3518552
hemopoietic marrow function in chronic neutropenia of blacks: cure of aplastic anemia by allogeneic marrow transplantation from a neutropenic sibling donor.	a black patient with severe aplastic anemia is described who underwent successful bone marrow transplantation from a sibling with chronic neutropenia. during an evaluation to identify a suitable donor, it was found that the majority of family members tested had neutropenia, with no familial history of significant infections or related hospitalizations. in vitro hemopoietic culture studies of marrow from the patient's hla-mlc-matched siblings showed normal numbers of pluripotential and committed ...	2012	3518419
protease-induced immunoregulatory activity of platelet factor 4.	intravenous injection of human or mouse serum or platelet material secreted from appropriately stimulated platelets ("releasate") together with antigen alleviates the immunosuppression in sjl/j mice induced by injection of irradiated lymphoma cells or in (cb6)f1 mice induced by injection of concanavalin a. we now report that injection of releasate from 10(6) human platelets restores plaque-forming cells to the unsuppressed number; greater amounts increase responses further. immunoregulatory acti ...	1986	3517862
ige antibody against surface antigens of leishmania promastigotes in american cutaneous leishmaniasis.	as ige-mediated immune mechanisms participate in the host defence against some types of parasites, we evaluated sera from american cutaneous leishmaniasis (acl) patients for the presence of this antibody against leishmania. using monoclonal antibodies against human ige and an immunoperoxidase staining technique, 48% of the patients sera tested were found to contain ige antibody that bound strongly to leishmania promastigotes. a much lower proportion of sera from non-symptomatic subjects from eit ...	1986	3517764
feasibility of same-day identification of members of the family vibrionaceae by the api 20e system.	sixty isolates, comprising nine species of the family vibrionaceae, were tested with the api 20e 5-h same-day procedure (analytab products, plainview, n.y.). included were 27 aeromonas hydrophila isolates, 10 aeromonas sobria isolates, 7 aeromonas caviae isolates, 3 plesiomonas shigelloides isolates, 3 vibrio alginolyticus isolates, 3 vibrio cholerae isolates, 1 vibrio fluvialis isolate, 5 vibrio parahaemolyticus isolates, and 1 vibrio vulnificus isolate. the 5-h profile numbers were specific fo ...	1986	3517061
the effect of insulin and catecholamines on the activities of 3-hydroxy-3-methyl glutaryl coenzyme a reductase and acyl-coenzyme a: cholesterol-o-acyltransferase in isolated rat hepatocytes.	this study was concerned with the effect of insulin and catecholamines on the rate limiting enzymes of cholesterol metabolism in rat hepatocytes. insulin was found to increase the activity of 3-hydroxy-3-methyl glutaryl coenzyme a reductase and to have no effect on the activity of acyl-coenzyme a: cholesterol-o-acyltransferase. noradrenaline and isoprenaline increased the activities of both 3-hydroxy-3-methyl glutaryl coenzyme a reductase and acyl-coenzyme a: cholesterol-o-acyltransferase. the e ...	1986	3516768