Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| a seroepidemiological study of human toxocara infection in the slovak republic. | sera of 908 blood donors, average age 35 years, living in towns and villages of the slovak republic were tested for toxocara canis antibodies using an elisa-igg test. the seroprevalence in the healthy population was estimated at 13.65%. antibodies were predominantly demonstrated in the sera from persons living in rural communities (17.09%) compared to the sera investigated from urban communities (11.82%). women had a significantly higher seropositivity than men. the serological response in 2703 ... | 1993 | 8132974 |
| presence of lipids in the secretory/excretory product from toxocara canis. | the presence of lipids in the secretory/excretory product obtained from toxocara canis has been demonstrated. the fatty acids found were mostly saturated, such as myristic (14:0), palmitic (16:0) and stearic (18:0). in addition, important quantities of oleic and linoleic acids (18:1 and 18:2) and cholesterol were detected. three more fatty acids appearing in low percentages are still to be identified. | 1993 | 8128580 |
| adult toxocara canis encephalitis. | a 48-year-old patient with toxocara canis infection developed severe ataxia, rigor and neuropsychological disturbances. an aetiology was proven by an indirect immunofluorescence test. ct and mri revealed both diffuse and circumscribed white matter lesions. angiography showed multiple occlusion of branches of the middle cerebral artery. anthelminthic treatment was beneficial in the initial stage of the disease, but had no effect on progression of cns symptoms. immunosuppressive therapy with predn ... | 1994 | 8126514 |
| experimental murine toxocariasis histopathological study of chronic renal infection, transplacental transmission and ultrastructural study of egg shell. | histopathological examination of kidney of swiss albino mice, 2 1/2 months after infection with toxocara canis eggs revealed various pictures of pathological affection. there was diffuse mesangioproliferative glomerulonephritis with mesangeal expansion of most of glomeruli. some glomeruli showed severe hyalinosis with marked adhesions to the bowman's capsule. the lumina of glomerular capillaries were markedly obliterated. there was also cystic dilatation of tubules with proteinaceous casts. the ... | 1994 | 8077752 |
| [ascaridiasis zoonoses: visceral larva migrans syndromes]. | the syndrome of visceral larva migrans is a zoonotic disease due to the migration in human of nematodes larval, specially ascarid. since the larvae fail to complete their migrating cycle in humans, the diagnosis of toxocariasis infection remains only serologic. we have been able to demonstrate by the technique of agar diffusion and the western-blotting method that the etiology due to toxocara canis was twice as much frequent as the one due to toxocara cati in the syndrome of visceral and ocular ... | 1994 | 8076198 |
| infectivity of toxocara canis larvae from japanese quails in mice. | two hundred toxocara canis larvae derived from japanese quail liver were given orally to each of 50 8-week-old ddy mice and parasitism of the larvae was examined during 6 hr and 120 days after inoculation. although there were no clinical signs in infected mice, larvae were recovered from the liver (21.5 +/- 16.3 larvae), lung (5.1 +/- 6.0 larvae), kidney (0.7 +/- 1.1 larvae), small intestine (1.0 +/- 2.0 larvae), mesentery (1.6 +/- 3.1 larvae), and brain (7.8 +/- 6.8 larvae). | 1994 | 8075236 |
| [preparation of membrane proteins of trichinella spiralis larva and application of them in detection with elisa]. | membrane proteins of muscle larva of trichinella spiralis (t.s) were isolated by using the non-ionic detergent triton x-114. at least fourteen components in the membrane proteins were separated with sds-page and then silver nitrate stain. the bands of them were located between 99-18kd mw level. the mw of chief bands were 94, 90, 47, 32 and 28kd. the sensitivity and specificity of these proteins were determined with elisa. they didn't cross react with sera of rabbits infected with toxocara canis ... | 1994 | 8070772 |
| intestinal helminth parasite community in wolves (canis lupus) in italy. | from 1987 to 1993, 89 wolves (canis lupus) collected throughout the whole italian range were examined for intestinal helminth parasites. twelve species were found, including 5 nematodes (uncinaria stenocephala, toxocara canis, ancylostoma caninum, trichuris vulpis and toxascaris leonina) and 7 cestodes (echinococcus granulosus, taenia hydatigena, t. multiceps, t. pisiformis, t. ovis, mesocestoides lineatus and dipylidium caninum). no significant differences were detected between sexes. t. canis ... | 1993 | 8065823 |
| [how many patients with visceral toxocariasis in russia?]. | based on the results of numerous seroepidemiological surveys of inhabitants in russia using the toxocara/igg enzyme immune test system and supposing that extremely high antibody titers (1:6400 or higher) are an indicator of manifest visceral toxocariasis, the possible number of patients with this infection was estimated in the russian federation. the absolute number of the patients is roughly 550,000, the relative rate is 380 per 100,000 population. children aged 0-9 years were shown to prevail ... | 1994 | 8015514 |
| [rheumatologic aspects of toxocariasis (visceral larva migrans). apropos of 2 cases]. | visceral larva migrans is a human infection by the larvae of dog ascarids or, more rarely, ascarids of other animal species. it is endemic in france. two cases which respectively manifested as acute oligoarthritis and inflammatory myalgia with increased muscle enzyme levels are reported. manifestations of the minor forms of this infestation are reviewed. | 1993 | 8012340 |
| dusn occurs in europe. | 1994 | 8008358 | |
| cloning and high level expression of gene encoding es antigen from trichinella spiralis muscle larvae. | the partial structure gene encoding es antigen derived from trichinella spiralis (tsp) muscle larvae was cloned, characterized, and expressed in e. coli. the target dna (0.7 kb) was directly obtained from the tsp total rna by using rna pcr technique. based on the analysis with the re digestion, the fragment was cloned into the fusion expression vector pex31c. it was shown that a kind of 37kda fusion protein was expressed in e. coli containing the recombinant plasmid by sds-page electrophoresis. ... | 1994 | 7993968 |
| [frequency of finding helminths eggs in canine stool samples collected in public places in the la plata city, argentina]. | a study was carried out in order to determine the level of contamination with helminth eggs in different sectors of the city of la plata, argentina. a total of 351 fecal pools were collected from streets (328) and parks and public places (23) of this locality. of these fecal pools, 117 (33.3%) contained eggs of at least one helminth species. the overall frequencies found were: uncinaria sp. 16.0%, trichuris vulpis 9.7% and toxocara canis 10.5%. | 1993 | 7993539 |
| epidemiology of human toxocariasis in la réunion. | in la réunion island (indian ocean) a seroepidemiological survey for toxocariasis was carried out among 387 subjects over 15 years old by western blotting using toxocara canis excretory-secretory larval antigens; 92.8% of the sera were positive. statistical study, including logistic regression analysis, showed a significant correlation of western blot results with sex, age, and absence of water supply. the final logistic model demonstrated that only the last 2 factors were significant multiplica ... | 1994 | 7992328 |
| toxocara canis and human health. | 1994 | 7980773 | |
| efficacy of fenbendazole against giardiasis in dogs. | efficacy of fenbendazole at 2 dosages for treating naturally acquired giardiasis in dogs was assessed. giardia cysts were not detected in the feces of 6 of 6 group-1 dogs (as determined by use of the zinc sulfate concentration technique) after fenbendazole treatment (50 mg/kg of body weight, po, q 24 h, for 3 doses). cysts were not detected in the feces of 6 of 6 group-2 dogs after fenbendazole treatment (50 mg/kg of body weight, po, q 8 h, for 3 days). however, cysts were not detected in the fe ... | 1994 | 7978640 |
| influence of soil texture in the recovery of toxocara canis eggs by a flotation method. | in epidemiological surveys, the evaluation of soil contamination by toxocara canis eggs requires a quick and easy method for the isolation of parasite eggs from soil samples. the efficiency of flotation methods is influenced by sample size, soil texture, degree of soil contamination, pretreatment, flotation solutions and time of flotation. this investigation was designed to evaluate the influence of soil texture in the recovery of t. canis eggs with the centrifugal flotation technique of dada (d ... | 1994 | 7975122 |
| [the helminth fauna of red foxes (vulpes vulpes linne 1758) in the administrative district of karlsruhe. 2. nematodes]. | between february 1989 and january 1990 a total of 801 foxes were examined for the presence of nematodes in the stomach and the small intestine and 835 foxes for the presence of trichinella spiralis larvae. the animals came from the german federal administration area of karlsruhe. the following nematodes in order of frequency were found: toxocara canis (30.2%), uncinaria stenocephala (24.3%), toxascaris leonina (2.0%) and ancyclostoma caninum (1.1%). the investigation of the muscles of all animal ... | 1994 | 7956813 |
| toxocara canis (nematoda, ascarididae): ultrastructure of the rachis and the ovarian wall. | the oogonia and oocytes in the ovaries of toxocara canis are joined to a cytoplasmic process called the rachis. the rachis is a much branched cytoplasmic mass without cell components in the germinal zone. at the end of the germinal zone and in the growth zone the cytoplasmic mass is formed into a central axial cylinder, containing small dense granules, lipid drops and glycogen. throughout the growth zone shell granules similar to those present in the oocytes are also present in the rachis. anter ... | 1994 | 7927063 |
| [diagnosis and treatment of eye infections caused by the canine ascaris larva toxocara canis]. | in the years 1990-1993 the authors diagnosed and treated 48 children on account of uveitis probably caused by toxocara canis. this etiology was established in 43 cases based on the characteristic clinical picture and presence of antibodies as determined by the elisa test for toxocara in serum, anterior chamber fluid and vitreous. diagnostic punction of anterior chamber was done in 30 cases (in 18 titres were positive, in 7 higher than in serum), in 3 the level of antibodies were determined in vi ... | 1994 | 7897994 |
| studies on the control of toxocara canis in breeding kennels. | the control of toxocara canis was investigated in naturally infected unweaned puppies. anthelmintic treatments were administered to three litters of pups at 2, 4 and 6 weeks of age. when either a new combination anthelmintic containing febantel, pyrantel embonate and praziquantel or fenbendazole was used, the faecal egg output over the first 7 weeks of life was reduced by more than 80% and worm burdens by over 90%. in contrast, piperazine adipate had no appreciable effect on t. canis egg output, ... | 1994 | 7886923 |
| the behavior and pathogenicity of toxacara canis larvae in mice of different strains. | in the present study the behavior and pathogenicity of second-stage larvae of toxocara canis were examined in different mouse strains with special emphasis on the major histocompatibility complex (mhc). mice of the inbred strains balb, c3h, c57bl, and dba and the outbred strain nmri were infected orally with 1000 second-stage larvae of t. canis. the clinical behavior of the animals; the numbers of larvae detected in the liver, lungs, brain, and musculature; the hematological and serological para ... | 1994 | 7886040 |
| role of small mammals in the epidemiology of toxocariasis. | studies were conducted on the role of small mammals in maintaining toxocariasis foci in urban, rural and montane biotopes. the lowest relative density of small mammals was recorded in the urban locality and the highest in the rural and montane localities. anti-toxocara antibodies were most frequently detected in synanthropic and hemisynanthropic species mus musculus, apodemus agrarius and micromys minutus--32.0, 30.4 and 25.0%, respectively. the highest seropositivity was found in small mammals ... | 1995 | 7885737 |
| toxocara-induced eosinophilic inflammation. airway function and effect of anti-il-5. | the immunoinflammatory response to parasitic nematode infections and allergic diseases have some similarities, the most profound being the increases in eosinophils and serum total ige concentration. whether parasitic infections stimulate or inhibit allergic asthma is a matter of debate. we investigated the effect of toxocara canis (t. canis) infection on airway function in balb/c mice at various days post-infection. within 24 h after infection, the trachea responded hyperreactive to carbachol st ... | 1995 | 7881685 |
| antibody to interleukin 5 prevents blood and tissue eosinophilia but not liver trapping in murine larval toxocariasis. | mice previously sensitized by infective-stage larvae of the canine nematode, toxocara canis, trap large numbers of challenge larvae within the liver; trapped larvae are found within eosinophilic granulomas. to investigate the role of eosinophils in this phenomenon we examined larval trapping in mice depleted of blood and tissue eosinophils by treatment with a monoclonal antibody (moab) (trfk-5) produced against recombinant murine interleukin 5 (rmil-5). control mice received either an isotype-ma ... | 1993 | 7877847 |
| mechanisms of eosinophilia in toxocara canis infected mice: in vitro production of interleukin 5 by lung cells of both normal and congenitally athymic nude mice. | mechanisms of eosinophilia were compared between in vitro bone marrow cell cultures of congenitally athymic (nu/nu) mice and their heterozygous littermates (nu/+). cultures of 5 x 10(4) bone marrow cells using interleukin 3 (il-3), il-5 and granulocyte-macrophage colony-stimulating factor showed that nu/nu and nu/+ mice mimicked each other in eosinophil production both before and after infection with toxocara canis. eosinophil differentiating activity (eda) was detected in media conditioned by s ... | 1993 | 7877846 |
| mr in toxocara canis myelopathy. | we present the case of a 23-year-old woman with cerebrospinal fluid eosinophilia and myelopathy caused by toxocara canis and describe the clinical and thoracic mr findings. an enhancing thoracic spinal cord lesion which was shown on mr resolved after an interval of 140 days with partial resolution of the patient's symptoms. | 1994 | 7863942 |
| [changes in the lungs in mice caused by migration of toxocara canis larvae]. | the influence of t. canis larvae migration on the lung tissue of paratenic host (inbred mice, strain c57bl6/j) was evaluated. first macroscopic manifestation was already observed on day 2 in the time of the highest larval recovery. larvae entering the lung tissue caused numerous small extravasations. their migration from the lungs was manifested from day 6 with an increase in the number and extent of extravasations. the lungs assumed tiger spot appearance (fig. 1). the larval recovery was decrea ... | 1994 | 7863576 |
| workshop summary: parasitic zoonoses--new issues. | 1994 | 7846860 | |
| effect of immunomodulation on the course of experimental toxocariasis in mice. | immunosuppressed groups treated with cortisone showed fulmination of toxocara canis infection in terms of significant increase in brain parasitism, total larval count and significant decrease in the percentage reduction of the total count. suppression of the host inflammatory responses was detected in the liver, lungs, brain and muscles. accelerated transit of larvae through the liver was observed when cortisone was given before infection. whether bcg was given before or after infection, it show ... | 1994 | 7844434 |
| [acute eosinophilic pneumonia and the larva migrans syndrome: apropos of a case in an adult]. | toxocariasis is a frequent disease in children, but the severe clinical manifestations are rare in the literature (diffuse interstitial pneumonia with hypoxaemia and acute severe asthma). the diagnosis is made thanks to the reliability of serological techniques (the elisa test and using antigen excretion-secretion tests of the larvae of toxocara canis). the authors report a case of acute severe eosinophilic pneumonia whose outcome was rapidly favourable following steroid therapy; the existence o ... | 1994 | 7831510 |
| prevalence of toxocara canis ova in public playgrounds in the dublin area of ireland. | a total of nine playground sites in dublin city and county were surveyed from which 228 samples were removed. of these samples, 15% were positive for toxocara canis ova and a mean egg density of 1.4 ova/100 g was calculated. two types of playground sites were identified and that the level of toxocaral contamination was found to be greater in 'neighbourhood playgrounds' than in 'adventure playgrounds'. there was no significant difference in the number of positive samples taken from sites both ins ... | 1994 | 7829844 |
| chronic urticaria and toxocara canis. | 1995 | 7823695 | |
| preferential expression of cd30 by human cd4+ t cells producing th2-type cytokines. | a large panel of human cd4+ t helper (th) cell clones with established th1, th2, or th0 profiles of cytokine secretion were examined for the expression of cd30, a member of the tumor necrosis factor receptor superfamily. th1 clones expressed poor or no cd30 mrna, and showed low or undetectable expression of both membrane and soluble cd30 (scd30) protein, whereas th2 clones showed both cd30 mrna and membrane cd30 and released substantial amounts of scd30. th0 clones exhibited an intermediate patt ... | 1995 | 7821763 |
| epidemiologic approach to human toxocariasis in western france. | toxocara canis is a common parasite in puppies. the danger to human health has not been properly established. we estimated the current incidence of this pathogen in two western districts of france, loire-atlantique and maine et loire. blood samples from 1836 eosino-philic patients were collected and tested by an enzyme-linked immunosorbent assay (elisa) excretory-secretory toxocara antigen test. we obtained positive results in 22% of the cases and highly positive results in 7%. the elisa data se ... | 1994 | 7809006 |
| [effect of environmental conditions on parasitic infection of dogs]. | the following intestinal parasites: dipylidium caninum, taenia hydatigena, trichocephalus vulpis, ancylostoma caninum, uncinaria stenocephala, toxocara canis, toxascaris leonina, ascaris sp. have been found on the basis of coprological investigations of 120 dogs from the wrocłow shelter, 20 dogs from wrocłow flats and 20 dogs from rural area of kielce district. total extensity of infection of rural dogs was 100% and 40-48% in town. these differences, according to the authors, are connected with ... | 1994 | 7801643 |
| devitalization of bacterial and parasitic germs in sewage sludge during aerobic digestion under laboratory conditions. | the survival of 8 bacterial species (pseudomonas sp., salmonella sp., enterobacteriae, streptococcus sp., escherichia coli) was detected in municipal sewage sludge up to 37 hours of mesophilic aerobic digestion under laboratory conditions. the model strain enterococcus faecium ccm 4231 survived almost twice as long as the above-mentioned isolates. similar findings, regarding the viability of the microorganisms studied, were also determined during thermophilic aerobic digestion of municipal sewag ... | 1995 | 7793018 |
| comparison of the efficacies of three heartworm preventives against experimentally induced infections with ancylostoma caninum and toxocara canis in pups. | forty 11- to 12-week-old helminth-naive beagles were categorized by sex and weight and randomly assigned to 4 treatment groups (group 1, ivermectin/pyrantel pamoate; group 2, milbemycin oxime; group 3, untreated control; group 4, diethylcarbamazine/oxibendazole). each pup was inoculated po with approximately 100 infective ancylostoma caninum larvae and 100 larvated toxocara canis eggs on day 0, and repeatedly at 7-day intervals thereafter until day 56. administration of anthelmintics also began ... | 1995 | 7782242 |
| [ocular toxocariasis or retinoblastoma?]. | seroprevalence studies in spain have shown that a high number of the population has been in contact with toxocara canis although no cases of ocular involvement by this helminth have been described. the clinical and age of presentation makes differential diagnosis with retinoblastoma necessary, which is at time difficult, although essential since the treatment and prognosis are very different. | 1995 | 7779878 |
| toxocara canis adult worm antigen induces proliferative response of healthy human peripheral blood mononuclear cells. | the proliferative response of human peripheral blood mononuclear cells (pbmc) from healthy donors to toxocara canis adult worm antigens (tca) was examined. pbmc from all donors examined (n = 7) strongly responded to tca in a dose-dependent fashion after six days of culture, irrespective of their serological reactivity. in contrast, cord blood mononuclear cells did not react to tca. the proliferation of pbmc in response to tca was completely inhibited by anti-hla-dr antibody. purified cd4+ t cell ... | 1995 | 7761111 |
| mechanisms of eosinophilia in balb/c-nu/+ and congenitally athymic balb/c-nu/nu mice infected with toxocara canis. | we studied the mechanism of eosinophilia in balb/c-nu/+ (nu/+) and balb/c-nu/nu (nu/nu) mice infected with toxocara canis. eosinophilia with two peaks on days 11 and 21 of infection was observed in infected nu/+ mice, and with a peak on day 11 in nu/nu mice. interleukin-5 (il-5) mrna was expressed on day 5 of infection in the lung and spleen of nu/+ mice and in the lung of nu/nu mice, but not in the spleen of nu/nu mice. large numbers of eosinophils and lymphocytes infiltrated the lung of both m ... | 1995 | 7751031 |
| [eosinophilic meningo-encephalo-myelitis due to toxocara canis]. | a 21-year-old woman was admitted to our hospital because of frontal headache, low-grade fever and convulsion. the patient had long been in a close contact with a dog. neurologic examination revealed meningeal irritation signs and cerebellar ataxia. slight leukocytosis with an increased rate of eosinophils (23.2%) was present. a lumbar puncture yielded 330 leukocytes/microliters with 30% of eosinophils; protein, 55 mg/dl; and increased igg synthesis, 43.6 mg/day. the antibody titer against toxoca ... | 1994 | 7729097 |
| effect of various doses of infective toxocara canis and toxocara cati eggs on the humoral response and distribution of larvae in mice. | the effect of 5-2,500 infective toxocara canis and 5-1,000 t. cati eggs on the humoral immune response and on the distribution of larvae in the organism was studied in paratenic hosts--inbred c57bl6/j mice. with each dose of t. canis eggs the maximal antibody level was recorded on day 56 post infection and was followed by a moderate decline that lasted until day 154 of the experiment. a correlation between the antibody level and the egg count was observed only with the infective dose of 5-50 egg ... | 1995 | 7724509 |
| [a case of toxocara canis infection]. | 1995 | 7722397 | |
| larval distribution of toxocara canis in balb/c mice at nine weeks and one year post-inoculation. | the migratory route of toxocara canis in the mouse includes two phases: a hepato-pulmonary phase and a myotropic-neurotropic phase. a study was made of the migratory behaviour of larvae one year post-inoculation (p.i.) comparing the results to those obtained at the end of an initial experiment (day 63 p.i). the larval distribution per organ was already definitive at 9 weeks p.i. the total parasitic load showed a reduction when the experiment was prolonged for one year. | 1994 | 7706687 |
| epidemiology of toxocara spp. in stray dogs and cats in dublin, ireland. | a survey was undertaken to study the epidemiology of toxocara spp. in 350 dogs and 181 cats. a prevalence of 82.6% was recorded for toxocara canis and 42% for t. cati. the distribution of parasite burdens in both dogs and cats was overdispersed. the highest parasite prevalence rates and burdens were found in hosts of 12 to 24 weeks of age. no toxocara parasites were found in cats between 0 to 4 weeks old. there was no significant difference in parasite prevalence between male and female dogs or ... | 1994 | 7706682 |
| dirofilaria immitis: detection of parasite-specific antigen by monoclonal antibodies in glomerulonephritis in infected dogs. | for the identification of circulating parasite antigens associated with immune-complex glomerulonephritis in dogs infected with dirofilaria immitis, monoclonal antibodies (mabs) were generated against adult worms. a total of 11 mabs were selected for cloning because of their high productivity and their lack of cross-reactivity with toxocara canis in indirect immunofluorescence tests. the ability of mabs to detect circulating antigens was examined using an antigen-capture enzyme-linked immunosorb ... | 1993 | 7682327 |
| the aba-1 allergen of the nematode ascaris suum: epitope stability, mass spectrometry, and n-terminal sequence comparison with its homologue in toxocara canis. | aba-1 is a major allergen of nematode parasites of the genus ascaris which includes the large roundworms of humans and pigs, a. lumbricoides and a. suum, respectively. the allergen was purified from a. suum by immunoaffinity chromatography for immunochemical examination. the ige antibody repertoire is under mhc control in infected rodents and the ige-binding epitopes were robust to treatment with heat or periodate, and electroblotting on nitrocellulose. this implies that the ige epitopes compris ... | 1993 | 7682160 |
| cross-reactions of sera from toxascaris leonina and ascaris suum infected mice with toxocara canis, toxascaris leonina and ascaris suum antigens. | the elisa method using larval es products and homogenized toxocara canis, toxascaris leonina and ascaris suum adult worms extract, was used to determine the possible cross-reactions in balb/c and c57bl/10 mice inoculated with embryonated eggs or adult worms extract of t. leonina of t. leonina or a. suum in single and multiple doses. when we used sera of mice infected with embryonated eggs of t. leonina against different heterologous ag, no cross-reactions against t. canis es and a. suum es ag we ... | 1995 | 7657459 |
| toxocara canis: ultrastructural aspects of larval moulting in the maturing eggs. | the morphology of the surface of toxocara canis larvae, developing in the eggs to reach infectivity, has been studied for the first time at an electron microscopical level. in most 11-day and some 15-day eggs, the larvae are surrounded by two shed cuticles. the outer first shed cuticle is composed of two layers. the inner second shed cuticle is much thicker than the outer one. the presence of both shed cuticles indicates that the larva has undergone two developmental stages in the maturing egg. ... | 1995 | 7657453 |
| mobility inhibition and nematocidal activity of asarone and related phenylpropanoids on second-stage larvae of toxocara canis. | the in vitro effect of asarone, the nematocidal principle of the rhizome of acorus calamus, on second-stage larvae of toxocara canis is composed of two independent actions: one is a fast acting inhibition of the larval mobility and the other is a slow acting larvicidal action. mobility of the larvae was rapidly inhibited when they were incubated with asarone. dye exclusion assay revealed that larvae were alive at this stage, and their mobility was restored after the first inhibition, suggesting ... | 1995 | 7655436 |
| [familial seroepidemiology of toxocariasis]. | with the objective of defining the intrafamiliar distribution pattern of the infection and illness caused by toxocara sp., 78 infected families (356 people) were studied for 30 months. at the same time 28 families free of infection were studied, as a control group (97 people). the socioeconomic level was analyzed according to a modified graffar index. contac with canine and feline pets, and antecedents of geophagia and onichophagia were found to be risk factors which would facilitate the infecti ... | 1994 | 7654285 |
| occurrence of interleukin-5 production by cd4- cd8- (double-negative) t cells in lungs of both normal and congenitally athymic nude mice infected with toxocara canis. | we studied cells in the lungs of balb/c and balb/c-nu/nu (nude) mice infected with toxocara canis, which produced interleukin-5 (il-5) in in vitro culture with larval excretory-secretory antigen (esag). the proportion of cd4+/cd8+/cd4- cd8- cells in lungs of both balb/c and nude mice was unchanged before and after infection with t. canis. panning and complement-mediated lysis using monoclonal antibody (mab) to cd4 showed that cd4+ cells in the lung from both mice produced il-5. anti-cd4 mab supp ... | 1995 | 7642218 |
| [evaluation of soil sanitation on poznan beaches based on helminth examination]. | it was proved that the soil of recreational areas can be potential source of human geohelminthiosis. the eggs of ascaris lumbricoides and trichocephalus trichiurus as well as of toxocara canis were found on the beaches of poznań lakes. | 1995 | 7638966 |
| the effects of freezing on the viability of toxocara canis and t. cati embryonated eggs. | suspensions of embryonated (l2) toxocara canis and t. cati eggs were maintained under freezing conditions in order to study the impact on their long term viability. the eggs had been removed from the uteri of adult toxocara spp. worms and the suspended in a 0.4% formalin solution before being frozen in 20 ml plastic tubes in the freezer compartment of a domestic refrigerator. assessment of embryonated egg viability over a period of 34 days was conducted by microscopic examination under a high li ... | 1995 | 7636161 |
| evaluation by larval recovery of mebendazole activity in experimental murine toxocariasis. | we have studied the action of mebendazole on experimental murine toxocariasis using different formulations and vehicles. the treatment efficacy was evaluated by larval recovery after digesting several tissues. in the first part of the experiment, the drugs were administered on days 1-3 post infection (p.i.) inclusive (hepato-pulmonary phase of the migration), then the animals were sacrificed by the 1st week p.i. in the second part of the experimental protocol, the treatments were administered on ... | 1995 | 7635636 |
| meiosis and some aspects of cytological mechanisms of chromosomal sex determination in nematode species. | meiotic division in toxascaris leonina, baylisascaris transfuga, hexametra sp., toxocara canis, t. cati, heterakis gallinarum and physaloptera clausa of the class nematoda were studied. chromosomal sex determination type in different taxa is described. the xx-xo type of sex determination predominates in the species examined. a y chromosome occurs only in b. transfuga. a correlation between the number and length of sex chromosomes and autosomes in the different taxa was established. | 1995 | 7635621 |
| optic neuritis in cerebral toxocariasis. | 1995 | 7629546 | |
| an abundant, trans-spliced mrna from toxocara canis infective larvae encodes a 26-kda protein with homology to phosphatidylethanolamine-binding proteins. | a full-length mrna encoding a secreted 26-kda antigen of infective larvae of the ascarid nematode parasite toxocara canis has been identified. this was characterized as a 1,082-base pair clone highly abundant (0.8-1.9%) in cdna prepared from infective stage larvae but absent from cdna from adult male worms. sequence analysis revealed an open reading frame corresponding to a hydrophilic 263-amino acid residue polypeptide with a 20-residue n-terminal signal peptide, indicating that it is secreted. ... | 1995 | 7629180 |
| a study on patients with eosinophilia of suspected parasitic origin. | a study of 53 patients with eosinophilia of suspected parasitic origin was conducted. investigations done for each case included, stool and urine examinations, absolute eosinophilic count and countercurrent immunoelectrophoresis (ciep) using crude antigens of fasciola hepatica, schistosoma mansoni worms, trichinella spiralis and toxocara canis larvae, and hydatid fluid. stool examination revealed six cases with fasciola eggs, two with ascaris lumbricoides and one with s. mansoni eggs. the eosino ... | 1995 | 7602166 |
| epidemiological studies on intestinal helminth parasites of rural and urban red foxes (vulpes vulpes) in the united kingdom. | an epidemiological study of intestinal helminths in 843 foxes (vulpes vulpes) from southern england revealed the presence of 13 parasite species: five nematodes--toxocara canis (prevalence 55.9%), toxascaris leonina (1.5%), uncinaria stenocephala (68.0%), trichuris vulpis (0.5%) and capillaria aerophila (0.2%); four cestodes--taenia pisiformis (13.8%), taenia hydatigena (2.5%), echinococcus granulosus (0.1%) and dipylidium caninum (3.8%); two trematodes--brachylaima recurva (2.9%) and cryptocoty ... | 1995 | 7571336 |
| serological evidence for the presence of toxocariasis in the turkana district of kenya. | 1995 | 7570867 | |
| a study on the prevention of prenatal and galactogenic toxocara canis infections in pups by treatment of infected bitches with ivermectin or doramectin. | investigations were carried out to test the efficacy of a two dose treatment with ivermectin or doramectin on reactivated larvae of toxocara canis in bitches to prevent prenatal and galactogenic infections of their pups. thirty pregnant bitches were treated by subcutaneous injection of ivermectin or doramectin on day 40 and 50 post conception (p.c.) each with a dose of 1 mg/kg body weight. the efficacy of the treatments was determined by faecal examinations and by comparing the number of infecte ... | 1995 | 7550440 |
| idiotypic replica of a toxocara canis excretory/secretory antigen epitope. | this study describes the production, characterization and use of an anti-idiotype serum raised against the monoclonal antibody tc-1 which recognizes a t. canis excretory/secretory antigen (es ag) epitope. anti-idiotypic (anti-id or ab2) antibodies were produced in rabbits using tc-1 f(ab')2 fragments; these anti-id inhibited es ag binding to biotinylated tc-1, and also inhibited a larval microprecipitation assay using tc-1. assays show that the ab2 beta or "internal image" of a t. canis es ag ep ... | 1995 | 7541025 |
| clinical and laboratorial features of visceral toxocariasis in infancy. | forty children with a diagnosis of visceral toxocariasis were evaluated prospectively from february 1982 to june 1989. diagnosis was established by clinical, laboratory and serological (elisa - es toxocara canis antigen) evaluations. a great clinical polymorphism was found in our patients, ranging from unspecific or absent manifestations to an exuberant symptomatology. the laboratory findings were: leukocytosis, eosinophilia and elevation of serum gammaglobulin and isohemagglutinin levels. no si ... | 1994 | 7527930 |
| immune responses to nematode exoantigens: sensitizing antibodies and basophil histamine release. | high levels of ige and eosinophilia are found in both allergy and helminth infections, but allergic symptoms are rare in naturally acquired helminth infections. the interrelation of specific ige antibodies and in vitro basophil histamine release (hr) induced by exoantigens from the larval stages (l2/l3) of the nematodes toxocara canis and ascaris suum was examined in 148 patients visiting an outpatient clinic for parasitic diseases. the antigen sensitivity of the basophils was found to be depend ... | 1994 | 7521141 |
| visceral larva migrans (toxocariasis) in toronto. | a 7-year-old child was admitted to toronto's hospital for sick children in 1976 with symptoms and laboratory findings compatible with visceral larva migrans, a disease usually caused by toxocara canis. this prompted a search for other cases seen at the hospital during the period 1952 through 1978. only 18 cases were discovered that met at least three of six criteria and thus were considered possible or probably cases of the disease. three possible cases of ocular toxocariasis during the same per ... | 1981 | 7459767 |
| [helminths of the common fox (vulpes vulpes l.) from the massif central (france) (author's transl)]. | sixty nine wild foxes originating from auvergne for the period january 1977 to january 1978 have shown intestinal parasites in the proportion of 76,8 per cent. 59,4 per cent are invaded with cestodes; 72,4 per cent with nematodes and none with trematodes. the list of the identified species is following: 1. cestodes. a) adults and fertile forms of: mesocestoides litteratus in 27,5 per cent of the hosts; taenia crassiceps in 15,9 p.c.; t. polyacantha in 27,5 p.c.; echinococcus multilocularis in 7, ... | 1980 | 7458165 |
| veterinary and public health considerations in canine roundworm control: a survey of practicing veterinarians. | we conducted a survey to assess whether current veterinary practices concerning prophylaxis and treatment of canine roundworm (toxocara canis) infection are adequate to prevent the potential public health risks of visceral larva migrans. we administered a standard questionnaire by telephone to 100 small animal practitioners. fifty-four veterinarians included health education for the pet's owner as part of their routine care in a case of canine roundworm infection, and 39 recommended prophylactic ... | 1980 | 7440322 |
| recovery of large numbers of eosinophils from mice infected with toxocara canis. | as a method of recovering large numbers of eosinophils, mice were infected with toxocara canis which in 12 days produced a high peripheral eosinophilia; the mice were then injected intraperitoneally with an extract of t. canis adult or anisakis larval worms. two days after injection of extract, peritoneal exudates were withdrawn, washed, and enumerated; the exudates were observed to be 70--80% eosinophils with a mean total recovery of 1 x 10(8) eosinophils per mouse. | 1980 | 7435785 |
| [intestinal helminths in bangkok stray dogs and their role in public health (author's tranls)]. | feces examination of 107 stray dogs in bangkok, thailand, on intestinal helminths showed the following rates: hookworms 100%, trichuris vulpis 54.2%, toxocara canis 6.5%, gnathostoma spinigerum 2.8%, spirocerca lupi 17.8%, diphyllobothrium mansoni 1.9%, and opisthorchis viverrini 1.9%. out of these species hockworms (especially a. braziliense), t. canis, g. spinigerum, and d. mansoni are important sources of human cutaneous or visceral larva migrans, the latter two being special parasites of the ... | 1980 | 7435002 |
| a paper radioimmunosorbent test (prist) for the detection of larva-specific antibodies to toxocara canis in human sera. | a paper radioimmunosorbent test (prist) was shown to be sensitive and reproducible when used with excretory/secretory antigen of toxocara canis second stage larvae. whatman no. 50 filter paper (5 mm discs) gave the most consistent and clear results with antigen at a concentration of 100 micrograms/ml, and could be stored for up to 3 weeks in vacuo at -70 degrees c. antigen coated discs were incubated with test sera at 1:10 dilution for 3 h at room temperature (21 degrees c), reacted with [125i]a ... | 1980 | 7430660 |
| a survey of canine toxocariasis and toxocaral soil contamination in essex county, new jersey. | toxocara canis eggs were found in the feces of 33 of 246 dogs and in two of 629 soil samples from 32 public parks in essex county, new jersey. stool samples collected from these areas were free of t. canis eggs. the findings suggest that contamination of soil in public parks with t. canis eggs is not an important factor in the transmission of visceral larva migrans in this county. | 1980 | 7425196 |
| human toxocariasis in a rural community. | a questionnaire and serologic survey of a pennsylvania community revealed that 23 (54%) of 43 study participants had antibody titers to toxocara canis (enzyme-linked immunosorbent assay test [elisa]) in the range defined as positive (greater than or equal to 1:32). age-specific seropositivity rates were highest among adults (greater than or equal to 18 years). positive titers ranged from 1:32 to 1:512. seropositivity did not cluster by family, and seropositivity rates were significantly higher t ... | 1980 | 7424857 |
| studies on the incidence of toxocara and toxascaris spp. ova in the environment. 1. a comparison of flotation procedures for recovering toxocara spp. ova from soil. | seven different flotation fluids were assessed for their efficiency in recovering toxocara canis ova from artificially seeded soil samples. using the most efficient (a saturated solution of magnesium sulphate plus 5% potassium iodide) 25 g amounts of 234 environmental soil samples were examined for the presence of toxocara spp. and toxascaris ova. twenty-six samples (11.1%) yielded ova of one or other species. there was no discernible pattern of distribution of positives with relation to the sou ... | 1980 | 7351480 |
| adult toxocara canis in the pancreas and peritoneal cavity of a pup. | 1981 | 7340792 | |
| retinal arterial obstruction in association with presumed toxocara canis neuroretinitis. | 1981 | 7337346 | |
| ocular toxocariasis demonstrated by ultrasound. | a 10-year-old white girl had a painless loss of central vision in the right eye. a white mass partially surrounded by blood was present in the macula of the right eye. ultrasound examination revealed an elevated mass. elisa test for toxocara canis was positive. further history revealed contact with puppies. the elisa test ruled out tumor. | 1981 | 7337343 |
| results of surgery for ocular toxocara canis. | it has been shown that the diagnosis of ocular toxocara canis is highly accurate when the typical clinical findings are associated with a positive elisa titer in the serum of 1:8 or greater. the inflammatory reaction in this disorder can be devastating and not infrequently leads to a tractional detachment of the posterior pole or a rhegmatogenous detachment and/or a progressive cyclitic membrane leading to phthisis bulbi. we have recently performed vitreoretinal surgery on 17 patients with compl ... | 1981 | 7335312 |
| the effect of temperature and antimetabolites on antibody binding to the outer surface of second stage toxocara canis larvae. | in vitro maintained second stage toxocara canis larvae do not bind antiserum raised to their excretions and secretions (es) at 37 degrees c as detected by indirect fluorescence. however, when these larvae were incubated at 2 degrees c under the same conditions intense fluorescence on the whole outer surface was observed. this fluorescence remained as long as the larvae were maintained at 2 degrees c. when these larvae were reincubated at 37 degrees c a gradual loss of fluorescence along their ou ... | 1981 | 7329441 |
| [behavior of toxocara canis werner 1782 (anisakidae) larvae during and following lung migration in the definitive host (beagle)]. | 1981 | 7324639 | |
| the effect of corticosteroid therapy on infection with toxocara canis in dogs. | three, six-month-old dogs were infected with 2,000 eggs of toxocara canis. three weeks after infection 15 immature adult parasites were found in the intestine of the dog which had been treated with high doses of corticosteroids (2 ml of opticortenol s given every four days) while no parasites were found in the intestine of the dog treated with repeated injections of 0.3 ml opticortenol s or in the untreated control dog. the increased susceptibility to infection with t. canis in the dog treated w ... | 1981 | 7324542 |
| ocular toxocariasis presenting as leukocoria in a patient with low elisa titer to toxocara canis. | a 4-year-old white female presented with leukocoria of the right eye. white punctate lesions were observed posterior to the retrolental membrane, which suggested retinoblastoma of some examiners. a full history, physical examination, ultrasonography, and ct scan failed to rule the diagnosis of retinoblastoma in or out. a serum elisa titer was 1:4, which was considered nondiagnostic. examination of the enucleated eye revealed a midsegment of the second stage larva of toxocara canis. the strengths ... | 1981 | 7322480 |
| [high-grade visual acuity impairment caused by parasite-induced uveoretinitis during toxocara canis infection (author's transl)]. | 1981 | 7321470 | |
| immunopathology of ascarid infection of the eye. role of ige antibodies and mast cells. | the roles of ige antiascarid antibodies and mast cells were compared in passively sensitized guinea pigs and animals infected intravitreally with ascarid larvae (toxocara canis, ascaris suum). intravenous ige antibody disappeared from the serum within 48 hours, but induced a hypersensitive state that persisted for 28 days. in systemically immunized animals, the aqueous-serum ige antibody ratio was 1:1,000 or less. passive periocular anaphylactic reactions produced an infiltration of neutrophils ... | 1981 | 7295137 |
| [prenatal and galactogenic infections with toxocara canis werner 1782 (anisakidae) in mice]. | 1981 | 7293559 | |
| [effect of various benzimidazole carbamates on somatic larvae of ancylostoma caninum ercolani 1859 (ancylostomidae) and toxocara canis werner 1782 (anisakidae). 1. studies in white mice]. | 1981 | 7282180 | |
| toxocara canis and lead alter consummatory behavior in mice. | ingestion of palatable and unpalatable solutions was measured in adult mice in which had been administered the common parasite of the dog, toxocara canis alone, or in combination with lead. in addition, response to hot plate and susceptibility to electroconvulsive seizure were also measured. results from the palatability test indicated that either lead or toxocara may alter the mouse's mode of interacting with its environment. however, the two agents in combination interacted in their effects on ... | 1981 | 7272805 |
| [occurrence of toxocara canis and other endoparasites in dogs in west berlin]. | 1981 | 7271732 | |
| comparative anthelmintic efficacy of two schedules of mebendazole treatment in dogs. | two schedules of anthelmintic oral treatment, using mebendazole powder, were compared in 73 dogs naturally infected with common helminth intestinal parasites. mebendazole powder was administered to 26 dogs at doses of 22 mg/kg once daily for 3 days and was compared with the same dose given only daily for 5 days into 23 dogs. the 24 other dogs were kept as controls and received a placebo treatment for 5 days. efficacy results for the 3-day treatment schedule of mebendazole were as follows: toxoca ... | 1981 | 7271006 |
| behavioral effects of lead and toxocara canis in mice. | adult mice were administered the common parasite toxocara canis or lead or both. the parasite clearly altered mouse performance on tests of exploration, activity, learning, and motor coordination; behavioral effects in mice receiving lead alone were less general. consequence of toxocara administration appeared attenuated in animals receiving both agents. parasite larvae were found in the central nervous system in all infected mice. | 1981 | 7268424 |
| [toxocara canis (larva migrans visceralis) from an ophthalmological point of view (author's transl)]. | visceral larva migrans (toxocara canis) is usually a relatively benign disease which is caused by infective second-stage larvae of the common cosmopolitan ascarid of dogs, characterized chiefly by sustained eosinophilia, pulmonary symptoms and hepatomegaly. its severity varies with the number of larvae in the tissue and the immune or allergic state of the infected individual. the most important aspect of the neurotropic larvae perhaps is its potential as a facilitating agent, for instance, for v ... | 1980 | 7253511 |
| antibodies to canine helminth parasites in asthmatic and nonasthmatic children. | we studied the prevalence of ige and igg antibodies to toxocara canis and dirofilaria immitis, helminth parasites of dogs, in asthmatic and nonasthmatic children born and raised in hawaii. the serologic pattern of the two groups was found to differ significantly. of the 80 asthmatic subjects, 45.0% had ige antibody and 17.5% igg-precipitating antibody to one or both parasites. in contrast, of the 96 nonasthmatic children studied 7.5% were positive for ige antibody and 31.3% positive for igg anti ... | 1981 | 7251191 |
| serological response of ascarid-free dogs to toxocara canis infection. | antibodies to toxocara were measured by enzyme-linked immunosorbent assay (elisa) in sera of ascarid-free dogs which had been fed 0, 100 or 10 000 embryonated t. canis eggs. dogs fed 10 000 eggs developed higher titres than those given 100 eggs and larvae failed to complete their migration to the gut. in addition, in dogs given 100 eggs, there was a significant negative correlation between the number of worms in the gut and granulomatous foci in the lung. the data suggest that the elisa is sensi ... | 1981 | 7243347 |
| anthelmintic tests on toxocara canis infection in mice. | one hundred and forty mice were infected orally with 1000 embryonated toxocara canis eggs. groups of 10 mice were then treated with high doses of piperazine, mebendazole, oxfendazole, albendazole, fenbendazole and diethylcarbamazine for four days, either immediately after infection or three weeks after infection. the mice were killed three to six weeks after treatment and the number of larvae in the brains and muscles estimated and compared with those in untreated mice. few larvae were recovered ... | 1981 | 7233781 |
| pica patterns, toxocariasis, and elevated blood lead in children. | blood samples were obtained during a lead screening program from 100 children aged 1-6 years in allegheny county, pennsylvania, to determine whether there was any association between specific forms of pica and infection with toxocara canis, the principal cause of visceral larva migrans in the united states, or elevated blood lead levels. significant associations were found between: 1) feces, soil, or grass pica and toxocara infection; 2) paint or plaster pica and elevated blood lead; and 3) dog ... | 1981 | 7212174 |
| [larva migrans visceralis (toxocara canis) and the central nervous system (author's transl)]. | 1980 | 7207683 | |
| parasitological investigation of children's sandboxes and dog faeces from public areas of housing development in prague. | two hundred sand samples from 50 children's sandboxes and 500 samples of dog faeces collected in 10 prague housing developments were examined for the presence of parasites. eggs of three helminth species were found in 28% of sandboxes and eggs and oocysts of 10 species of parasites were found in 10.4% of dog faeces. toxocara canis occurred in 9 sandboxes and 3.2% of dog faeces, t. cati in 0.2% of dog faeces. the results from housing developments are compared with those from older estates. | 1982 | 7201949 |
| antibody to toxocara canis in the aqueous humor. | the aqueous humor and serum samples of patients with presumed ocular toxocariasis were examined by an enzyme-linked immunosorbent assay (elisa) for antibody to the embryonated egg antigen. using a single dilution (1:8), higher amounts of antibody have been found in the aqueous humor than in the serum samples. antibody was not found in the serum or aqueous humor of patients with retinoblastoma, coats' disease, uveal malignant melanoma, or central retinal artery obstruction. while two patients wit ... | 1981 | 7197150 |
| an investigation of variables in a fecal flotation technique. | several variables in a standard vial fecal gravitational flotation technique were investigated. these were the specific gravity of the sodium nitrate flotation solution, duration of flotation and mesh sizes of strainers. the number of eggs which floated and adhered to a coverslip were counted and estimates of the number of eggs remaining in the strained fecal suspension and in the feces trapped on the strainer were made. eggs from hookworms, trichuris vulpis and toxocara canis in feces from dogs ... | 1980 | 7190861 |