Publications

demonstration and partial characterization of antigens of rickettsia rhipicephali that induce cross-reactive cellular and humoral immune responses to rickettsia rickettsii.	the relatively unrelated spotted fever group rickettsia rickettsia rhipicephali conferred on guinea pigs protective immunity against challenge with virulent r. rickettsii. immunity was conferred at all doses of r. rhipicephali used in the study. because of the serologic unrelatedness of these two rickettsiae, determined by the use of microimmunofluorescence and other serological assays, further studies were performed to define the nature of the immune response elicited by r. rhipicephali and the ...	1992	1452343
experimental evidence of ischemic thresholds and functional recovery.	impaired blood flow below certain critical levels and an insufficient supply of energy-rich substrates cause failure of neuronal function, triggering biochemical disturbances that eventually lead to ischemic cell damage.	2005	1440719
pharmaceutical promotions.		2006	1435909
a cluster of tick-borne infections: association with military training and asymptomatic infections due to rickettsia rickettsii.	during the spring of 1989, 86 members of a military unit from the state of maryland, usa, participated in two-week-long training manoeuvres in the states of arkansas (location fc) and virginia (location faph). acute febrile illnesses due to infections with two tick-borne pathogens, rickettsia rickettsii and ehrlichia sp., were confirmed serologically in 2 initial cases who were admitted to the hospital. a seroepidemiological investigation among unit members found an additional 17 of 109 individu ...	1992	1412666
health status of the temporarily homeless population and residents of north west thames region.	to survey the health status of the temporarily homeless population of north west thames region and make comparisons with regional residents.	2006	1392918
[torsion of the colonic epiploic appendages].	operations were carried out on 21 patients with torsion of epiploic appendages of the colon (sigmoid 19, ascending 1, hepatic flexure 1). this pathologic condition has no specific manifestations and occurs under the mask of other emergencies. the suggested symptom of "pain displacement" in combination with other signs allowed the correct diagnosis to be established before the operation in two thirds of patients. patients with torsion of epiploic appendages must be subjected to an emergency opera ...	2006	1388218
specificity of a tumor marker (ca54/61) and its individual epitopes recognized by monoclonal antibodies, ma54 and ma61, in human tumor patients.	the specificity of a tumor marker (ca54/61) and its individual epitopes (ca54 and ca61) recognized by monoclonal antibodies (ma54 and ma61) and expressed by the same tumor marker were studied. serum levels of ca54 and ca61 were compared with that of ca54/61. in lung adenocarcinoma and ovarian carcinoma, the positive rates of ca61 (42% and 68%) were higher than those of ca54 (32% and 32%) and similar to those of ca54/61 (45% and 74%). the serum levels of ca54 and ca61 showed a significant correla ...	1992	1383482
[morbidity with temporary loss of work capacity in the workers of the belmeken-sestrimo hydroelectric cascade].	the present work presents the results from the analysis on the morbidity with temporary disability from cascade "belmeken-sestrimo" (n = 94, men 73, women 21). by means of personnel method are studied the cases of morbidity with temporary disability and defined the basic and enlarged number of indices, analysed in sex, age, length of service, nosological structure and dynamics for a period of 3 years (1987-1989) for the 3 sites of hydroelectric cascade "belmeken-sestrimo", water-power station "m ...	2005	1364540
african tick-bite fever: a new spotted fever group rickettsiosis under an old name.		1992	1357393
dopamine agonists and pituitary tumor shrinkage.	the primary aim of this review has been to clarify the tumor shrinking effects of dopamine agonists on pituitary macroadenomas of different cell types. shrinkage is most dramatic for macroprolactinomas and is due to cell size reduction. seventy-nine percent of 271 definite macroprolactinomas were reduced in size by at least 25%, and 89% shrank to some degree. most shrinkage occurs during the first 3 months of treatment, although in a minority shrinkage is delayed. dopamine agonist resistance dur ...	2006	1352243
susceptibility of rickettsia conorii, r. rickettsii, and coxiella burnetii to pd 127,391, pd 131,628, pefloxacin, ofloxacin, and ciprofloxacin.	plaque formation and dye uptake assays were used to measure the mics of pd 127,391 and pd 131,628 against rickettsia species. the mics of pd 127,391 were 0.25 microgram/ml for rickettsia rickettsii and 0.125 to 0.25 microgram/ml for rickettsia conorii. the mics of pd 131,628 were 0.25 to 0.5 microgram/ml for r. rickettsii and 0.5 microgram/ml for r. conorii. as determined by the shell vial technique, 15 strains of coxiella burnetii were susceptible to pd 127,391 and pd 131,628 (mic, < or = 1 mic ...	1992	1336950
rickettsia rickettsii induces superoxide radical and superoxide dismutase in human endothelial cells.	human endothelial cells infected with rickettsia rickettsii, the etiological agent of rocky mountain spotted fever, undergo striking morphological changes to the endoplasmic reticulum-outer nuclear envelope complex. these changes are accompanied by concurrent accumulation of intracellular peroxides. both of these findings are consistent with the notion that cells undergo some form of oxidative stress. since oxidant injury is often initiated or mediated through oxygen radicals, we examined supero ...	1992	1333449
determination of genome sizes of rickettsia spp. within the spotted fever group, using pulsed-field gel electrophoresis.	the chromosome lengths of six spotted fever group rickettsia species (rickettsia rickettsii, r. conorii, r. rhipicephali, r. sibirica, r. australis, and r. akari) were estimated by pulsed-field gel electrophoresis. the genome size of r. rickettsii was about 2,100 kb, but the chromosome lengths of the five other species were, surprisingly, much lower and ranged between 1,200 and 1,300 kb.	1992	1331027
identification of actin kinase activity in purified fragmin-actin complex.	actin kinase phosphorylates actin of fragmin-actin complex, resulting in the inactivation of the nucleation and capping activities of the complex. fragmin-actin complex was prepared by a new purification procedure. incubation with atp caused inactivation of the purified complex and phosphorylation of actin of fragmin-actin complex. the detailed analysis of the complex by sds-gel electrophoresis showed that actin kinase was co-purified with the fragmin-actin complex. formation of such an associat ...	2003	1326442
[spotted fever: isolation of rickettsia from a skin biopsy sample].	a 2 years old child living in an area of the state of são paulo, known in the past as endemic for rickettsiosis developed clinical evidences of spotted fever after a tick bite. rickettsiae were isolated from guinea pigs inoculated with a skin homogenate. in sera tested by indirect immunofluorescence with rickettsia rickettsii standard antigen, igg specific antibody titers raised from 1:512 in the first sample to 1:2048 in the third one; igm specific antibody titer was 1:128 in the three samples. ...	1992	1307409
[immunotherapeutic approach in tuberculosis: thymus hormones].		2005	1287758
[clinico-immunologic shifts in myocardial infarct].		2005	1274315
[treatment of parkinsonism].		2005	1265907
toxoplasmosis after splenectomy in sickle cell disease. report of two cases with recurrence in one child two years following antitoxoplasmic therapy.		2005	1253508
[laryngeal suspension microsurgery].		2005	1230948
a volumetric assessment of pollen levels in the air of ann arbor, michigan.		2005	1196148
comparative morphology of genital cones of genus ancylostoma dubini, 1843.	male worms of ancylostoma braziliense, a. ceylanicum, a. kusimaense, a. malayanum, a. duodenale, a. caninum, a. tubaeforme, agriostomum vryburgi and cyclodontostomum purvisi have the external appendages beside the anogenital aperture. these anogenital structures are morphologically similar and are assumed to be homologous among the species with three pairs of teeth or more. in hookworms with two pairs of teeth, the anogenital structures are complex. anogenital features can be used as a taxonomic ...	1975	1166351
clinical evaluation of tumor scanning with 169-yb-citrate.	169-yb-citrate was used as the tumor-scanning agent in 360 patients with malignant tumors and in 55 others with benign lesions and the results compared with 67-ga-citrate studies in other series. in malignant tumors, the overall positive detection rate for ytterbium was 65.3%; in benign lesions, the false-positive rate was 29.1%. good results were obtained in the extremities, head and neck, and pelvic area. of all tumors visualized, squamous cell carcinoma was detected most effectively (77.5%). ...	2005	1153741
[the metastic development of breast carcinoma after surgical treatment of primary tumor. iv].		2005	1143694
an analysis of senile changes in the palpebral fissure.	this work was carried out to determine the changes in conformity and in physiological movements of the eyelids with advancing age. some conceptions fostered in the literature are false and should be discarded. others have been corroborated. we conclude that the whole lateral canthus becomes lax and drifts medially with age. therefore, surgical correction should aim at restoring the fixation of the lateral canthus to its youthful position.	2002	1122413
[lymphocyte populations in hbag-positive acute hepatitis].		2005	1087387
dynamic cisternography in normal dogs and in human beings.	cisternography and ventriculography were performed in five normal anesthetized dogs to study the dynamics of tracer dispersal. indium 111-diethylenetriaminepentaacetic acid was injected into lateral ventricles, cisterna magna, thoracic subarachnoid space, and lumbar sac. the patterns of dispersal from each injection site support a nonflow dispersal mechanism with a tendency toward ultimate equilibrium distribution throughout the cerebrospinal fluid. quantitative data in humans complement observa ...	1976	1082560
high resolution polyacrylamide gradient gel electrophoresis.	a method was developed for high resolution electrophoresis of proteins in linear gradient (3 to 30%) polyacrylamide gel rods in a neutral phosphate buffer containing 0.1% sodium dodecyl sulfate. well-defined protein zones were observed and improved resolution was attained especially for low molecular weight proteins in preparations containing a variety of polypeptides, e.g. viruses that are often separated by continuous gel methods. electropherograms of continuous (8%) and gradient (3 to 30%) ge ...	1976	1005359
interaction between coxiella burnetii and guinea pig peritoneal macrophages.	the phagocytosis and subsequent degradation of phase i and ii coxiella burnetii by macrophages obtained from immune and nonimmune guinea pigs were compared. phase i rickettsiae were more resistant to phagocytosis than were phase ii organisms. there was no significant difference in the percentage of phagocytosis of either phase of rickettsiae by macrophages from immune or nonimmune animals. after ingestion, phase i and ii organisms pretreated with normal serum multiplied and destroyed normal macr ...	1976	971955
studies on the pathogenesis of rickettsia rickettsii in the dog: clinical and clinicopathologic changes of experimental infection.	beagle dogs inoculated with the agent of rocky mountain spotted fever, rickettsia rickettsii, developed a clinical syndrome that extended from febrile exanthema to death and appeared to be dose related. infected dogs were anorectic and lethargic and developed cutaneous lesions characteristic of rocky mountain spotted fever, including petechia, ecchymosis, edema, and necrosis. hematologic changes after inoculation included anemia, leukopenia proceeding to leukocytosis, and thrombocytopenia. chang ...	1977	879582
mechanisms of transovarial infection of spotted fever rickettsiae in ticks.		1975	829476
vectors and vertical transmission: an epidemiologic perspective.		1975	829470
study of rickettsioses in slovakia. iii. experimental infection of apodemus flavicollis melch. by rickettsiae of the spotted fever (sf) group isolated in slovakia.	experimental studies of infection of apodemus flavicollis, and for comparison of rickettsiaemia in clethrionomys glareolus and of susceptibility and antibody formation in white mice, with rickettsiae of the sf group isolated in slovakia, gave the following results: the species a. flavicollis reacted by the formation of antibodies on subcutaneous administration of rickettsiae, strain b, in an amount of 10(0.5) eid50/0.25 ml, whereas the white mouse only in an amount of 10(2.5). rickettsiae, strai ...	1976	825571
infection cycle of rickettsia rickettsii in chicken embryo and l-929 cells in culture.	the infection cycle of rickettsia rickettsii, studied in slide chamber cultures of chicken embryo and l-929 cells, was found to be complex and did not conform to a one-step growth cycle. initial uptake kinetics resembled those established for rickettsia prowazekii, but subsequent events showed very marked differences. intracytoplasmic growth commenced exponentially without measurable lag. however, very soon after infection, intracytoplasmic rickettsiae began to escape from the host cell into the ...	1976	825463
prompt confirmation of rocky mountain spotted fever: identification of rickettsiae in skin tissues.	rickettsia rickettsii were identifiable by the immunofluorescence technique in skin specimens obtained by biopsy on days 4 and 8 of illness from patients with rocky mountain spotted fever. the immunofluorescence technique is regarded as a practical means of confirming the diagnosis during the early stages of illness before positive serologic reactions can be obtained.	1976	824374
new assay of protective activity of rocky mountain spotted fever vaccines.	areas under the fever curves of guinea pigs inoculated with rocky mountain spotted fever vaccine over a restricted dose range and infected with a standardized dose of rickettsia rickettsii varied linearly with log10 dose of vaccine. a calculator was programmed to plot fever curves and calculate the vaccine dose that reduced the fever of infected animals by 50%.	1976	823177
effect of vaccination schedule on immune response of macaca mulatta to cell culture-grown rocky mountain spotted fever vaccine.	the effect of vaccination schedule on the immune response of macaca mulatta to formalin-inactivated chicken embryo cell culture (cec)-grown rickettsia rickettsii vaccine was studied. schedules consisted of inoculation on day 1 only, on days 1 and 15, on days 1 and 30, on days 1, 8, and 15, or on days 1, 15, and 45. humoral antibody measured by microagglutination and indirect immunofluorescence and resistance to challenge with 10(4) plaque-forming units of yolk sac-grown r. rickettsii were assess ...	1976	823173
demonstration of rickettsia rickettsii in the rhesus monkey by immune fluorescence microscopy.	indirect immune fluorescence was used to detect rickettsiae in the tissues of a primate inoculated subcutaneously with rickettsia rickettsii. rickettsiae were identified by indirect immuno fluorescence predominantly in skin, skeletal muscle, scrotum, testicles, nares, heart, kidney, liver, brain, spleen, pancreas, and larynx. cell culture assay confirmed the presence of infectious organisms in those specimens.	1976	823168
functional and morphologic changes during experimental rocky mountain spotted fever in guinea pigs.	experimental rocky mountain spotted fever was studied in guinea pigs following intraperitoneal inoculation of 10(7) rickettsia rickettsii. after a 2-day incubation period, animals developed fever, progressive emaciation, and scrotal swelling with necrosis. vasculitis, with increased small vessel permeability for colloidal carbon, was evident in cremaster muscles as early as 1 day after inoculation. inflammatory changes in vessels became progressively more severe as numbers of circulating rickett ...	1976	822237
proteins of typhus and spotted fever group rickettsiae.	purified radioactive rickettsiae were obtained from irradiated and cycloheximide-inhibited l cells, and their proteins were analyzed by polyacrylamide gel electrophoresis. rickettsial species could be distinguished by comparing the relative mobilities of constituent proteins after migration of two differentially labeled preparations in a single gel. distinct differences were observed in gel patterns of rickettsiae from the typhus and spotted fever groups, as well as with different species within ...	1976	820639
rickettsiae belonging to the spotted fever group from ticks in the tribec mountains.	rickettsiae of the spotted (sf) group were found in a selected locality of the tribec mountains in southern slovakia in 1974. the rickettsiae were found in 10.8% of females and 6.1% of males of haemaphysalis inermis and 7.3% of females and 4.8% of males of ixodes ricinus. no significant differences in the incidence were observed during the year. coxiella burneti was found in 1 male and 4 females of h. inermis and 1 male of i. ricinus in ad adjacent locality. antibodies against rickettsiae of the ...	1976	820614
changes in blood serum constituents and hematologic values in macaca mulatta with rocky mountain spotted fever.	forty-seven male macaca mulatta, 3 to 4 kg weight, were inoculated intravenously or subcutaneously with various doses of yolk sac-grown rickettsia rickettsii. thirty-four macaques became febrile and exhibited signs of infection ranging from transient illness with a few days of fever to severe illness with subsequent death. the rash appeared more frequently in the macaques inoculated subcutaneously. febrile macaques that survived had leukocytosis, with concomitant neutrophilia. febrile macaques t ...	1976	820224
pathology of experimental rocky mountain spotted fever in rhesus monkeys.	rhesus monkeys were inoculated intravenously or intraperitoneally with various numbers of rickettsia rickettsii. monkeys that were given more than 10(4) organisms intravenously died on days 3-6 after inoculation, whereas those given less than 10(3) intravenously or more than 10(4) intraperitoneally died on day 7 or later. there was no significant difference in incidence of lesions between the early- and late-death groups. vasculitis and thrombosis occurred most frequently in the nares, pinna of ...	1976	820052
antibody response to rocky mountain spotted fever.	various techniques were compared to determine the most sensitive method for detection of rocky mountain spotted fever antibody. a radiometabolic technique for detection of rocky mountain spotted fever antibody is also described. in infected monkeys, the fluorescent antibody technique yielded the earliest evidence of seroconversion; with some monkeys the microagglutination procedure was equally effective. the fluorescent antibody and microagglutination measurements showed higher titers than those ...	1976	819455
alterations in plasma copper, zinc, amino acids, and seromucoid during rocky moutain spotted fever in guinea pigs.	guinea pigs inoculated with virulent rickettsia rickettsii responded with a significant increase in plasma copper concentration within 1 day, preceding fever and detectable rickettsemia by 2 and 4 days, respectively. a decrease in serum zinc concentration coinciding with peak rickettsemia was detectable on day 5. evidence of altered host nitrogen metabolism during this illness included a doubling of plasma seromucoid concentration and a significant rise in the plasma phenylalanine/tyrosine ratio ...	1976	817295
microimmunofluorescence test for the serological study of rocky mountain spotted fever and typhus.	a microimmunofluorescence test was used to study antibody responses to various spotted fever group and typhus group rickettsiae during rocky mountain spotted fever (rmsf) and epidemic typhus (et). patients with rmsf reacted most strongly to rickettsia rickettsii; those with et reacted predominantly to r. prowazekii. the degree of cross-reaction to other rickettsial strains varied from patient to patient, but a particular pattern of cross-reaction was consistently observed in serial sera from the ...	1976	815267
rocky mountain spotted fever in mississippi: survey for spotted fever antibodies in dogs and for spotted fever group reckettsiae in dog ticks.	during epidemiologic studies of rocky mountain spotted fever in mississippi in 1973, dogs were surveyed for antibodies tp spotted fever group antigens and for tick parasites infected with rickettsiae of the spotted fever group. fifty-three (46%) of 116 serum samples had complement-fixing antibody titers greater than or equal to 1:8 as compared to only one (5%) of 21 samples from a group of dogs obtained from metropolitan chicage. fifty-two per cent of the dogs tested from mississippi had microag ...	1976	814809
early diagnosis of rocky mountain spotted fever. use of primary monocyte culture technique.	diagnosis of rocky mountain spotted fever was made as early as the fourth day of febrile illness in rhesus monkeys (macaca mulatta), with a monocyte culture technique that is easily amenable to use in humans. rickettsia rickettsii were identified by direct immunofluorescent and gimenez staining of cultures of circulating monocytes from four experimentally infected monkeys, even in the presence of a mild or inapparent disease in three. levels of rickettsemia were estimated by the plaque-assay tec ...	1976	814256
evaluation ofprimary blood monocyte and bone marrow cell culture for the isolation of rickettsia rickettsii.	rickettsia rickettsii was isolated from experimentally infected guinea pigs by culture of blood monocytes and bone marrow cells, and from experimentally infected rhesus monkeys by blood monocyte culture. rickettsiae were identified in monocyte-macrophage monolayers stained by giménez or flourescent antibody techniques. a total of 78 culture attempts were made from 20 guinea pigs and 16 monkeys. the success of isolation of r. rickettsii in culture was positively correlated with the numbers of ric ...	1975	812828
indirect hemagglutination test for human antibody to typhus and spotted fever group rickettsiae.	an indirect hemagglutination (iha) test is described that uses glutaraldehyde-stabilized erythrocytes treated with a rickettsial erythrocyte-sensitizing substance obtained from rickettsia typhi or rickettsia rickettsii. the serological reagent was stable for at least 3 months at room temperature and 6 months at 4 c. it exhibited group specificity and no group cross-reactivity. at a minimum dilution of 1:40, acute and early convalescent epidemic and murine typhus antisera showed 86% positive reac ...	1975	811685
rocky mountain spotted fever (tick-borne typhus) in south carolina: an educational program and tick/rickettsial survey in 1973 and 1974.	because the incidence of spotted fever is increasing in south carolina, campaigns were carried out in 1973 and 1974 to provide the public and medical practitioners, through pamphlets and news media, with information about spotted fever and the ticks which transmit the causative agent, rickettsia rickettsii. people were also invited to save and submit live ticks removed from vegetation, animals and humans, for examination by the hemolymph test. a total of 1,186 ticks consisting of 987 dermacentor ...	1975	811127
a review of rocky mountain spotted fever (tick-borne typhus), its agent, and its tick vectors in the united states.		1975	810584
comparison of three rocky mountain spotted fever vaccines.	growth of rocky mountain spotted fever (rmsf) rickettsiae in duck embryo cell (dec) cultures and chicken embryo cell (cec) cultures was evaluated. experimental lots of duck embryo cell- and chicken embryo cell-grown rocky mountain spotted fever vaccines and a commercial lot of yolk sac-grown vaccine were compared for protective efficacy in rhesus monkeys. incidence and magnitude of antibody response, febrile response, and rickettsemia, as well as incidence of fatalities, suggested that both cell ...	1975	810494
preparation of rocky mountain spotted fever vaccine suitable for human immunization.	rocky mountain spotted fever vaccine was produced from rickettsiae grown in chicken embryo cells in roller bottle cultures. the rickettsiae were concentrated and purified by passage through a sucrose gradient and inactivated with formalin. this vaccine satisfactorily passed preinactivation and final container testing and is believed to be superior to the presently available yolk sac vaccine.	1975	809483
rhipicephalus sanguineus: vector of a new spotted fever group rickettsia in the united states.	a rickettsia related to but distinct from the spotted fever agent, rickettsia rickettsii, has been detected in 167 (18.9%) of 884 rhipicephalus sanguineus taken off dogs in central and northern mississippi. the organisms could readily be isolated in male meadow voles (microtus pennsylvanicus), where it produced massive infections in the tissues of tunica vaginalis. it was practically nonpathogenic for male guinea pigs, although inoculation of these animals with infected tunica vaginalis of voles ...	1975	806533
immunological properties of rickettsia rickettsii purified by zonal centrifugation.	the properties of rickettsia rickettsii purified from infected chicken yolk sacs or mouse l cell cultures by sucrose density gradient centrifugation in a zonal rotor were examined in various ways. rickettsiae derived from both l cells and yolk sacs had similar compositions: about 12% nitrogen, 1.5% phosphorus, 5% carbohydrate, and 30% fatty acids. on a dry-weight basis, purified rickettsiae were at least 2,000 times as effective as a commercial spotted fever vaccine in protecting guinea pigs aga ...	1975	806522
myocardial involvement in rocky mountain spotted fever.	rocky mountain spotted fever (rmsf), an acute febrile exanthematous illness caused by rickettsia rickettsii and transmitted by ticks, is endemic in the southern atlantic states. this report is based on the clinical and pathological findings of myocardial involvement in 16 children who died with severe rmsf. all 16 children had myocardial lesions to some degree, but it was not believed that these could be evaluated in terms of cardiac function and death in the face of the usual peripheral vascula ...	1978	580868
[alterations of plasma plasminogen and fibrinogen, serum fibrin degradation products and degree of adp induced platelet aggregation in acute myocardial infarction (author's transl)].		1980	550980
[chronic digestive loss of plasma proteins evaluated with 51cr-albumin in billroth i and ii gastrectomized patients].	the digestive clearance of albumin 51cr was determined in patients submitted to gastrectomy due to peptic ulcer, 6 to 18 months after surgery. patients were of both sexes, with ages varying from 24 to 70 years. reconstruction after resection was according to billroth i and ii techniques (groups b and c). the group of control (group a) presented no digestive illness. each group was represented by 10 individuals. the mean value and respective standard derivation for each group was respectively: gr ...	1980	550789
milk carbohydrates of marsupials. ii. quantitative and qualitative changes in milk carbohydrates during lactation in the tammar wallaby (macropus eugenii).	milk was collected at various stages of lactation from a group of tammar wallabies, m. eugenii, in which parturition had been synchronized. the milk carbohydrate was determined by a phenol-sulfuric acid method which had been modified to give equal colour yields for galactose and glucose. the mean carbohydrate content increased gradually during the first 6 months of lactation to a peak of 13 g hexose/100 ml of milk, but then fell rapidly to much lower values, over the following 2 months. througho ...	2005	549552
the interaction between legalization of abortion and contraception in denmark.	trends in fertility, abortion, and contraceptive practice in denmark were analyzed, using previously compiled official statistics; the conclusion was drawn that easy access to abortion may contribute toward a decline in contraceptive practice depending on the level of contraceptive practice in the population and on the degree of confidence the population has in available contraceptive methods. in october 1973 denmark passed a law permitting women to obtain free abortion on demand. the number of ...	2005	538953
kidney lesions in rocky mountain spotted fever: a light-, immunofluorescence-, and electron-microscopic study.	the essential pathologic lesion in rocky mountain spotted fever (rmsf) is a vasculitis that may involve the kidneys as well as the heart, brain, skin, and subcutaneous tissues. histopathologic information concerning the response of the kidneys in rmsf is rather limited, however. in this study renal tissue from 17 children who died of rmsf was examined by light, electron, and immunofluorescence microscopy. a lymphocytic or mixed inflammation, or both, involving vessels and interstitium of the kid ...	1979	525676
a sporadic case of legionnaires' disease in belgium.		2004	525201
the treatment of acute cholecystitis. a series of 497 consecutive patients.	in a five-year series of 497 consecutive patients with acute cholecystitis an overall mortality of 3.2% was observed. there was no significant difference in mortality between patients undergoing early surgery and those managed initially conservatively. the total incidence of postoperative complications was also similar in the early and delayed surgery groups, although wound complications were slightly more frequent after early surgery. a special risk group was formed by patients with unsuccessfu ...	2004	525185
[our experience in using artificial bands for ligamentoplasty in the knee region (author's transl)].		2004	509254
comparison of individual and cumulative dose-response curves [proceedings].		1979	497601
five-year findings of the hypertension detection and follow-up program. ii. mortality by race-sex and age. hypertension detection and follow-up program cooperative group.	data are reported for four race-sex and three age subgroups of the hypertension detection and follow-up program (hdfp). throughout the hdfp trial, for black men, black women, white men, and white women and for persons aged 30 to 49, 50 to 59, and 60 to 69 years at entry, control of blood pressure was consistently better for stepped care (sc) than referred care (rc) participants. this difference in degree of control was least for white women; it was less for whites than for blacks of the same sex ...	2004	490883
the efficacy of a potassium-rich diet compared to diuretic treatment on the renal elimination of thallium in the rat.		1979	454183
colonic adrenocarcinomas in patients with ureterosigmoidostomies.	two additional cases of adenocarcinoma of the sigmoid colon occurring at the site of ureterosigmoidostomy are reported. the high risk of this complication occurring in patients who have undergone ureterosigmoidostomy is described. the possible shortness of the interval from diversion to development of an adenocarcinoma, especially in those cases involving carcinoma of the bladder, is emphasized. it is strongly recommended that careful follow up of such patients should begin within several years ...	2004	446246
acute renal failure in rocky mountain spotted fever.	review of clinical and pathologic data from ten fatal cases of rocky mountain spotted fever (rmsf) revealed the importance of acute renal failure in the clinical course and of multifocal perivascular interstitial nephritis as the principal pathologic lesion. in nine cases, rickettsia rickettsii were demonstrated by immunofluorescence in the areas of vasculitis. evidence was lacking for the role of disseminated intravascular coagulation, glomerulonephritis, or myoglobinuria in the pathogenesis of ...	1979	434998
[contribution of the section medical pedagogy to the improvement of quality and effectiveness of health care].		2004	425577
[the psychodynamics of schizophrenia. 2. the current interpretation of the deficit theory, psychodynamic concepts outside psychoanalytic studies, theories on interpersonal dynamics, resp. family dynamics].		1978	422098
synthesis of plasma membrane proteins during development of dictyostelium discoideum.		1979	421897
incidence of ruptured chordae tendineae in the mitral valvular prolapse syndrome: an echocardiographic study.	echocardiographic studies were performed in 190 consecutive patients with mitral valvular prolapse. all patients had either midsystolic posterior motion of the mitral valve or holosystolic hammock-like movement of the valve in systole. thirteen patients (7 percent) were noted to have ruptured chordae tendineae. in four patients, a combination of abnormalities was observed. five patients had clinical and bacteriologic evidence of infective endocarditis, two of whom had severe intractable pulmonar ...	1978	421575
radiological evaluation of anal fistulae: a prospective study of fistulograms.	a review of 33 fistulograms in a four-year study is presented. four types of communicating tracts have emerged: single (58%), branched (18%), fistulous abscess (15%) and compound (9%). this classification has formed the basis of selection of operative treatment in all the cases. diminished lumbo-sacral angle was also found in most of the anal fistula cases and this establishes a possible association between the pathology of anal fistula and the low back syndrome.	1977	421419
genetic markers for schizotaxia.	evidence is presented for the occurrence of a locus for schizotaxia on the short arm of chromosome 6. this derives from study of 63 informative members of seven pedigrees in which the proband and a parent (or a sib of parent) suffered with schizophrenia and other kin were either normal or fell within a spectrum of conditions related to schizophrenia. for linkage of hla and schizotaxia a lod score, 2.57, at recombination frequency 0.15 is reported, which gives p = 0.008. this is in contrast to da ...	1976	420900
rocky mountain spotted fever caused by blood transfusion.	transfusion of 500 ml of blood, contributed by a donor three days before the onset of rocky mountain spotted fever and refrigerated for nine days, caused this disease in the recipient. the blood donor died of rocky mountain spotted fever after six days; rickettsia were identified in various tissues by immunofluorescence techniques. the recipient of the blood became mildly ill and recovered fully; specific antibiotic treatment was initiated on the fourth day of illness. diagnosis of rocky mountai ...	1978	418193
[cellular composition of the lymph nodes of monkeys (rhesus macaque) under normal and experimental conditions].	by means of mathematical methods, quantitative and qualitative changes were studied in different structural components of the mesenteric (ileocecal) lymph nodes in normal monkeys (macaca rhesus) and under per os administration of salmonella typhi murium, streptomycin-dependent. cellular composition was calculated in the cortical plateau, cortical (lymphoid) cords and in follicules. average percent of every cell type was determined. vaccine administration, was stated to inhibit cytopoiesis in the ...	1978	415703
listeria monocytogenes meningitis: case report.	a case of listeria monocytogenes septicaemia with meningitis is described. predisposing factors in this case included chronic liver disease, diabetes mellitus and liver malignancy. the infection responded poorly to ampicillin.	1977	415268
is partnership with parents really possible?		1975	415200
comparative electrophoresis of spotted fever group rickettsial proteins.		1978	415197
complement in cystic fibrosis.	complement components c3, c4, and c3a were estimated in 30 patients with cystic fibrosis aged 1 to 21 years (m:f = 16:14) and were compared with results in 40 healthy, age-matched subjects. the influences of the clinical score, sputum microbiology, and the patients' sex were also investigated. in contrast to most previous communications, this paper shows that, compared to the control group, a significant decrease of c3 (p less than 0.001) and c4 (p less than 0.02) was observed whereas c3a levels ...	1978	414916
[auricular fibrillation with ventricular tachycardia. surgical section of a left lateral bundle of kent].	the authors report the case of a man of 22 years, with no previous cardiac history, in whom a wolff-parkinson-white syndrome was discovered during the course of this first episode of atrial fibrillation with a ventricular rate of 300-350/mn; investigation (vecto-cardiogram, intra-cavitory ecg) showed the presence of a short circuit of the kent type, with a high permeability, and localised in the left lateral position; this was confirmed by pericardial cartography. after the surgical division of ...	1977	414674
[comparative precipitation studies between the highly-virulent virus of european swine fever, swine-fever-virus split products and precipitating swine-fever antigens from the organs of swine-fever infected pigs].		1977	414484
in vitro guinea pig leukocyte reactions to rickettsia rickettsii.	the presence of cell-mediated immunity in rocky mountain spotted fever-infected guinea pigs was determined by two in vitro assays: whole blood lymphocyte transformation (lt) and macrophage migration inhibition. increased lt was detected as early as 1 week in guinea pigs infected with rickettsia rickettsii and treated with oxytetracycline and was detected by two weeks in infected but untreated guinea pigs. elevated lt was still detectable at 10 weeks postinfection. guinea pigs vaccinated with kil ...	1977	412792
[isolation of rickettsia of the spotted fever group (sf group) from dermacentor marginatus ticks in tirol, austria].		1977	410728
[seroepidemiological investigations on the prevalence of rickettsial antibodies in man in the federal republic of germany (author's transl)].	1,600 random serum samples from inhabitants of hesse were investigated for rickettsial antibodies by complement fixation test. antibodies were found in 19 samples (1,2%) against rmsf-group antigen with titers between 1:10 and 1:640. these results confirm recent reports on natural foci of such rickettsial infections in the federal republic of germany. antibodies against rickettsia of the typhus-group or coxiella burnetii could not be detected by the complement fixation reaction. none of the sera ...	1977	410727
laboratory-acquired rocky mountain spotted fever. the hazard of aerosol transmission.	nine patients with laboratory-acquired rocky mountain spotted fever were seen during the period 1971 to 1976. investigation of each case revealed either definite or probable exposure to an aerosol containing infectious rickettsiae; in no case was there evidence of parenteral exposure either by accidental self-inoculation or by tick bite. these illnesses are believed to represent infection acquired via the respiratory route. this report emphasizes the aerosol hazard of rickettsia rickettsii in th ...	1977	409947
rickettsiae of the spotted fever group in slovakia.		1977	408981
rocky mountain spotted fever and the avoidance of sulfonamides.		1977	406374
studies of the coagulation and complement systems during experimental rocky mountain spotted fever in rhesus monkeys.	we studied the coagulation and complement systems during rocky mountain spotted fever in macaca mulatta experimentally infected with rickettsia rickettsii. ninety-one percent of monkeys infected intravenously with a high dose (10(6) plaque-forming units [pfu]) and 56% of monkeys infected with low doses (10(-1)-10(2) pfu) of r. rickettsii died after two to four days of illness. with the onset of fever and rickettsemia, animals developed hyperfibrinogenemia, mild thrombocytopenia, prolonged prothr ...	1977	405434
pathogenesis of infection with rickettsia rickettsii in the dog: a disease model for rocky mountain spotted fever.	dogs inoculated with rickettsia rickettsii developed a clinical syndrome ranging in severity from a mild febrile exanthema to death within six days after inoculation. the severity of the disease appeared to be dose-related, and the signs were comparable to r. rickettsii infection in humans on a clinical and hematological basis. dogs were rickettsemic for 10 to 14 days after infection. in most animals the level of rickettsemia was greater than or equal to 10(2.5) guinea pig intraperitoneal 50% in ...	1977	405432
differences in buoyant-density properties of coxiella burnetii and rickettsia rickettsii.	the pronounced change in the buoyant density of coxiella burnetii in cscl gradients that was caused by treatment with formalin or ultraviolet radiation was not observed with rickettsia rickettsii.	1977	403144
rocky mountain spotted fever: occurrence in massachusetts.		1977	402694
identification of rickettsia rickettsii in a guinea pig model by immunofluorescent and electron microscopic techniques.	moribund guinea pigs infected with richettsia rickettsii were examined by necropsy, histology, immunofluorescence, electron microscopy, and serology. untreated animals died at 9 and 10 days after inoculation. animals given saline subcutaneously survived from 1 to 4 days longer. prolonged survival was accompanied by more severe lesions: scrotal necrosis; infarction of ears; and swollen, hemorrhagic footpads, epididymis, and cremaster muscle. histopathologic examination demonstrated that acute, ne ...	1977	402079
a comparison of serologic methods for diagnosis of rocky mountain spotted fever.	sera referred to the north carolina division of health services for rickettsial serology in 1974 were tested by complement fixation (cf), microimmunofluorescence (micro-if), microagglutination (ma) and hemagglutination (ha) for antibodies against rickettsia rickettsii. there was good agreement among micro-if,ma and ha tests in detecting antibody responses to this agent, but the cf test was definitely less sensitive than the others, even in illnesses with classical clinical manifestations of rock ...	1977	401558
alteration in local and systemic immune capacity after exposure to bursts of co.		1979	387409
[theodor billroth (1829-1894), "pope of surgery", on the 150th anniversary of his birth].		2004	375156
[the control of renin secretion: experimental data and clinical implications].		2004	356832
initial clinical evaluation of a new rocky mountain spotted fever vaccine of tissue culture origin.	currently available rocky mountain spotted fever (rmsf) vaccines are relatively ineffective in preventing infections in humans and contain considerable amounts of contaminating egg protein. a new formalin-inactivated vaccine was prepared by sucrose density gradient centrifugation of the sheila smith strain of rickettsia rickettsii grown in chick embryo cell tissue culture. the new product has greater protective immunogenicity in rheusus monkeys and guinea pigs than commercial vaccines. six volun ...	1978	355580