Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| larvicidal, pupicidal, repellent and adulticidal activity of citrus sinensis orange peel extract against anopheles stephensi, aedes aegypti and culex quinquefasciatus (diptera: culicidae). | mosquitoes are the carriers of severe and well-known illnesses such as malaria, arboviral encephalitis, dengue fever, chikunguniya fever, west nile virus and yellow fever. these diseases produce significant morbidity and mortality in humans and livestock around the world. the present study explored the effects of orange peel ethanol extract of citrus sinensis on larvicidal, pupicidal, repellent and adulticidal activity against anopheles stephensi, aedes aegypti and culex quinquefasciatus. the or ... | 2012 | 22797605 |
| investigation of the cry4b-prohibitin interaction in aedes aegypti cells. | bacillus thuringiensis (bt) produces insecticidal toxins active against insects. cry4b, one of the major insecticidal toxins produced by bt subsp. israelensis, is highly toxic to mosquitoes in the genus aedes: the major vectors of dengue, yellow fever, and chikungunya. previous work has shown that cry4b binds to several mid-gut membrane proteins in aedes aegypti larvae including prohibitin, a protein recently identified as a receptor that also mediates entry of dengue virus into aedes cells. thi ... | 2012 | 22767320 |
| electroantennogram, flight orientation and oviposition responses of anopheles stephensi and aedes aegypti to a fatty acid ester-propyl octadecanoate. | studies were carried out to evaluate the role of a c(21)-fatty acid ester; propyl octadecanoate (po) for olfaction-mediated behavioral responses of urban malaria vector, anopheles stephensi and dengue vector, aedes aegypti mosquitoes using electroantennogram (eag), flight orientation and oviposition experiments. dose dependent electrophysiological responses were recorded for po from the antenna of both mosquito species in which 10(-5) g elicited significant eag response. an. stephensi exhibited ... | 2012 | 22750483 |
| larvicidal activity of morinda citrifolia l. (noni) (family: rubiaceae) leaf extract against anopheles stephensi, culex quinquefasciatus, and aedes aegypti. | morinda citrifolia leaf extract was tested for larvicidal activity against three medically important mosquito vectors such as malarial vector anopheles stephensi, dengue vector aedes aegypti, and filarial vector culex quinquefasciatus. the plant material was shade dried at room temperature and powdered coarsely. from the leaf, 1-kg powder was macerated with 3.0 l of hexane, chloroform, acetone, methanol, and water sequentially for a period of 72 h each and filtered. the yield of extracts was hex ... | 2012 | 22740293 |
| isolation of bacillus thuringiensis strains that contain dipteran-specific cry genes from ilha bela (são paulo, brazil) soil samples. | the entomophatogenic bacterium bacillus thuringiensis produces crystal proteins, named cry proteins which are encoded by the cry genes. this bacterium is used on biological control of important economical pests, as well as in the control of disease´s vectors, such as aedes aegypti, a mosquito that transmits the dengue viruses. isolates of this bacterium can be characterized by the content of cry genes and this prediction helps target different insect orders. in this research, we isolated 76 colo ... | 2012 | 22735130 |
| global climate change and its potential impact on disease transmission by salinity-tolerant mosquito vectors in coastal zones. | global climate change can potentially increase the transmission of mosquito vector-borne diseases such as malaria, lymphatic filariasis, and dengue in many parts of the world. these predictions are based on the effects of changing temperature, rainfall, and humidity on mosquito breeding and survival, the more rapid development of ingested pathogens in mosquitoes and the more frequent blood feeds at moderately higher ambient temperatures. an expansion of saline and brackish water bodies (water wi ... | 2012 | 22723781 |
| gene amplification, abc transporters and cytochrome p450s: unraveling the molecular basis of pyrethroid resistance in the dengue vector, aedes aegypti. | pyrethroid insecticides are widely utilized in dengue control. however, the major vector, aedes aegypti, is becoming increasingly resistant to these insecticides and this is impacting on the efficacy of control measures. the near complete transcriptome of two pyrethroid resistant populations from the caribbean was examined to explore the molecular basis of this resistance. | 2012 | 22720108 |
| modeling the transmission dynamics of dengue fever: implications of temperature effects. | the purpose of this study was to investigate the transmission dynamic modeling of dengue fever in subtropical taiwan by the contributing temperature-dependent entomological parameters of aedes aegypti. a vector-host transmission model was used to explore the temperature variation of pre-adult mosquito maturation, oviposition rate, adult mosquito death rate, and virus incubation rate in the mosquito. sensitivity analysis, by transmissible biting rate and the initial mosquito population, was adapt ... | 2012 | 22705874 |
| translational selection of genes coding for perfectly conserved proteins among three mosquito vectors. | the biased usage of synonymous codons affects translational efficiency of genes. we studied codon usage patterns of genes that are perfectly conserved at the amino acid level among three important mosquito vector species: aedes aegypti (vector of dengue virus), anopheles gambiae (vector of malaria) and culex quinquefasciatus (vector of lymphatic filariasis and west nile virus). although these proteins have the same amino acid sequences, non-random usage of synonymous codons is evident among the ... | 2012 | 22705463 |
| the antioxidant role of xanthurenic acid in the aedes aegypti midgut during digestion of a blood meal. | in the midgut of the mosquito aedes aegypti, a vector of dengue and yellow fever, an intense release of heme and iron takes place during the digestion of a blood meal. here, we demonstrated via chromatography, light absorption and mass spectrometry that xanthurenic acid (xa), a product of the oxidative metabolism of tryptophan, is produced in the digestive apparatus after the ingestion of a blood meal and reaches milimolar levels after 24 h, the period of maximal digestive activity. xa formation ... | 2012 | 22701629 |
| insecticidal activity against aedes aegypti of m-pentadecadienyl-phenol isolated from myracrodruon urundeuva seeds. | myracrodruon urundeuva fr. allemao is a common tree in the caatinga that has been widely used for various medical purposes. previous studies showed that the ethanol seed extract of m. urundeuva has potent activity against the larval stage of the dengue vector aedes aegypti. given this potential insecticidal activity, bioguided separation steps were performed in order to isolate the active compound(s). | 2012 | 22689540 |
| impacts of wolbachia infection on predator prey relationships: evaluating survival and horizontal transfer between wmelpop infected aedes aegypti and its predators. | the wmelpop strain of wolbachia is currently being investigated for its potential use as a biological control agent to reduce the ability of aedes aegypti (l.) mosquitoes to transmit dengue viruses. the survival of a potential wmelpop infected ae. aegypti strain for field release is important as a higher susceptibility to predation in the wmelpop strain could result in difficulties in achieving fixation. we investigated immature and adult survival as a function of susceptibility to predation by ... | 2012 | 22679870 |
| structure-activity relationships of eugenol derivatives against aedes aegypti (diptera: culicidae) larvae. | dengue fever is a severe public health problem for several countries. in order to find effective larvicides to aid control programs, the structure-activity relationships of eugenol derivatives against aedes aegypti (diptera: culicidae) larvae were evaluated. additionally, the composition and larvicidal activity of syzygium aromaticum essential oil was assessed. | 2012 | 22674880 |
| efficacy of sunlight-activatable porphyrin formulates on larvae of anopheles gambiae m and s molecular forms and an. arabiensis: a potential novel biolarvicide for integrated malaria vector control. | biolarvicides, such as microbial formulations based on bacillus thuringiensis and b. sphaericus, have been found to be highly effective against mosquito larvae and are currently employed as eco-friendly alternatives to synthetic chemical insecticides for vector control. recently, a porphyrin of natural origin has been suggested as a sunlight-activatable larvicide against the dengue vector aedes aegypti. in order to validate the approach for the control of the malaria vector, we tested the photo- ... | 2012 | 22668835 |
| the dengue situation in africa. | dengue outbreaks and epidemics have been reported in all regions of africa, and it is believed that all four dengue virus serotypes are in circulation. available data suggest that dengue is endemic to 34 african countries and that aedes aegypti mosquitoes--the primary vector for dengue transmission--are known to be present in all but five countries. whether populations in africa are susceptible to dengue at the same rates as in asia and latin america is difficult to determine from the available ... | 0 | 22668445 |
| dengue: an escalating public health problem in latin america. | dengue infection is a significant and escalating public health problem in latin america. its re-emergence and subsequent rise in the region over the past 50 years has largely been caused by a combination of a lack of political will, the radical growth of urban populations, migration flow and insufficient financial resources. its increased incidence has been compounded by climate change, poor sanitation and extreme poverty, which lead to more breeding sites of the mosquito vector aedes aegypti. i ... | 0 | 22668444 |
| using recombinant dna technology for the development of live-attenuated dengue vaccines. | dramatic increases in dengue (den) incidence and disease severity have been reported, in great part due to the geographic expansion of aedes aegypti and aedes albopictus mosquitoes. one result is the expanded co-circulation of all dengue 1-4 serotype viruses (denv) in urban areas worldwide, especially in south and south-east asia, and south america. den disease severity ranges from asymptomatic infections to febrile dengue fevers (df) to life-threatening dengue hemorrhagic fever (dhf) and dengue ... | 2012 | 22664189 |
| assessing the risk for dengue fever based on socioeconomic and environmental variables in a geographical information system environment. | an important option in preventing the spread of dengue fever (df) is to control and monitor its vector (aedes aegypti) as well as to locate and destroy suitable mosquito breeding environments. the aim of the present study was to use a combination of environmental and socioeconomic variables to model areas at risk of df. these variables include clinically confirmed df cases, mosquito counts, population density in inhabited areas, total populations per district, water access, neighbourhood quality ... | 2012 | 22639119 |
| lethal effects of aspergillus niger against mosquitoes vector of filaria, malaria, and dengue: a liquid mycoadulticide. | aspergillus niger is a fungus of the genus aspergillus. it has caused a disease called black mold on certain fruits and vegetables. the culture filtrates released from the a. niger atcc 66566 were grown in czapek dox broth (cdb) then filtered with flash chromatograph and were used for the bioassay after a growth of thirty days. the result demonstrated these mortalities with lc(50), lc(90), and lc(99) values of culex quinquefasciatus 0.76, 3.06, and 4.75, anopheles stephensi 1.43, 3.2, and 3.86, ... | 2012 | 22629156 |
| vertical transmission of dengue virus in aedes aegypti collected in surabaya, indonesia, during 2008-2011. | 2012 | 22627316 | |
| impact of road networks on the distribution of dengue fever cases in trinidad, west indies. | this study examined the impact of road networks on the distribution of dengue fever cases in trinidad, west indies. all confirmed cases of dengue hemorrhagic fever (dhf) observed during 1998 were georeferenced and spatially located on a road map of trinidad using geographic information systems software. a new digital geographic layer representing these cases was created and the distances from these cases to the nearest classified road category (5 classifications based on a functional utility sys ... | 2012 | 22609547 |
| intrinsic features of aedes aegypti genes affect transcriptional responsiveness of mosquito genes to dengue virus infection. | dengue virus infection causes significant morbidity and mortality in humans world-wide. the aedes aegypti mosquito is the major vector that spreads dengue virus to humans. interaction between dengue viruses and a. aegypti is a multi-factorial phenomena that is determined by both virus and mosquito genotypes. although, studies have suggested significant association of mosquito vectorial capacity with population variation of dengue virus, specifications of the vector factors that may influence vec ... | 2012 | 22579482 |
| mosquito bite delivery of dengue virus enhances immunogenicity and pathogenesis in humanized mice. | dengue viruses (denv) are transmitted to humans by the bite of aedes aegypti or aedes albopictus mosquitoes, with millions of infections annually in over 100 countries. the diseases they produce, which occur exclusively in humans, are dengue fever (df) and dengue hemorrhagic fever (dhf). we previously developed a humanized mouse model of df in which mice transplanted with human hematopoietic stem cells produced signs of denv disease after injection with low-passage, wild-type isolates. using the ... | 2012 | 22573866 |
| silica nanoparticle: a potential new insecticide for mosquito vector control. | presently, there is a need for increased efforts to develop newer and effective methods to control mosquito vectors as the existing chemical and biological methods are not as effective as in earlier period owing to different technical and operational reasons. the use of nanomaterial products in various sectors of science including health increased during the last decade. we tested three types of nanosilica, namely lipophilic, hydrophilic and hydrophobic, to assess their larvicidal, pupicidal and ... | 2012 | 22565400 |
| linking oviposition site choice to offspring fitness in aedes aegypti: consequences for targeted larval control of dengue vectors. | current aedes aegypti larval control methods are often insufficient for preventing dengue epidemics. to improve control efficiency and cost-effectiveness, some advocate eliminating or treating only highly productive containers. the population-level outcome of this strategy, however, will depend on details of ae. aegypti oviposition behavior. | 2012 | 22563512 |
| larvicidal activity of pectolinaringenin from clerodendrum phlomidis l. against culex quinquefasciatus say and aedes aegypti l. (diptera: culicidae). | larvicidal activity of 12 fractions and a compound of chloroform extract of clerodendrum phlomidis l. (lamiaceae) was assayed for their toxicity against the early fourth-instar larvae of the filarial vector culex quinquefasciatus say and dengue vector aedes aegypti l. the fractions were tested at 100-, 50-, 25- and 12.5-ppm concentrations. the compound pectolinaringenin was tested at 5-, 2.5-, 1.0- and 0.5-ppm concentrations. among the different fractions, fraction 5 recorded the lowest lc(50) a ... | 2012 | 22562213 |
| chikungunya virus infection, a threat to public health. | many countries in the world have reported human infections by chikungunya virus (chikv) a mosquito-borne togavirus belonging to the genus alpha virus. after half a century of focal out breaks of acute febrile poly arthralgia, the disease had spread unexpectedly in the past decade with large outbreaks in africa around the indian ocean and in bangladesh. in asia, chikv is thought to be transmitted by the same mosquito as dengue, aedes aegypti and aedes albopictus. due to similarities in clinical p ... | 2012 | 22561790 |
| community-based control of aedes aegypti by using mesocyclops in southern vietnam. | we previously reported a new community-based mosquito control strategy that resulted in elimination of aedes aegypti (linn.) in 40 of 46 communes in northern and central vietnam, and with annual recurrent total costs (direct and indirect) of only $0.28-$0.89 international dollars per person. this control strategy was extended to four provinces in southern vietnam in long an and hau giang (2004-2007) and to long an, ben tre, and vinh long (2005-2010). in a total of 14 communes with 124,743 reside ... | 0 | 22556087 |
| oviposition and flight orientation response of aedes aegypti to certain aromatic aryl hydrazono esters. | aedes aegypti is a day-biting, highly anthropophilic mosquito and a potential vector of dengue and chikungunya in india. a. aegypti is a container breeder, generally oviposit in the stored and fresh water bodies, and discarded containers near residential areas that provide suitable habitats for oviposition by gravid females. the diurnal activity and endophilic nature of these mosquitoes have increased the frequency of contact with human being. assured blood meal from human host in an infested ar ... | 2012 | 22552771 |
| the influence of larval density, food stress, and parasitism on the bionomics of the dengue vector aedes aegypti (diptera: culicidae): implications for integrated vector management. | new larval control strategies for integrated vector management of aedes aegypti are in high demand, including the use of biological control agents. exposure of aedes aegypti to parasites, starvation, and overcrowded conditions during larval development reduces the probability of survival to eclosion, can directly affect fitness parameters such as adult size and fecundity, and can affect the size, provisioning, and viability of eggs produced by females. we compared these parameters after exposing ... | 2012 | 22548557 |
| spatial and temporal dynamics of aedes aegypti larval sites in bello, colombia. | counts of immature stages of the mosquito aedes aegypti have been used to calculate several entomological indices of dengue vector abundance. some studies have concluded that these indices can be used as indicators of dengue epidemic risk, while other studies have failed to find a predictive relationship. ecological niche models have been able to predict distributional patterns in space and time, not only of vectors, but also of the diseases that they transmit. in this study, we used landsat 7 e ... | 2012 | 22548535 |
| increasing role of roof gutters as aedes aegypti (diptera: culicidae) breeding sites in guadeloupe (french west indies) and consequences on dengue transmission and vector control. | during the past ten years, the islands of guadeloupe (french west indies) are facing dengue epidemics with increasing numbers of cases and fatal occurrences. the vector aedes aegypti is submitted to intensive control, with little effect on mosquito populations. the hypothesis that important ae. aegypti breeding sites are not controlled is investigated herein. for that purpose, the roof gutters of 123 houses were systematically investigated, and the percentage of gutters positive for ae. aegypti ... | 2012 | 22548085 |
| evaluation of 15 local plant species as larvicidal agents against an indian strain of dengue fever mosquito, aedes aegypti l. (diptera: culicidae). | the adverse effects of chemical insecticides-based intervention measures for the control of mosquito vectors have received wide public apprehension because of several problems like insecticide resistance, resurgence of pest species, environmental pollution, toxic hazards to humans, and non-target organisms. these problems have necessitated the need to explore and develop alternative strategies using eco-friendly, environmentally safe, bio-degradable plant products which are non-toxic to non-targ ... | 2012 | 22536188 |
| variation in aedes aegypti (linnaeus) (diptera, culicidae) infestation in artificial containers in caxias, state of maranhão, brazil. | dengue is a serious public health problem worldwide, with cases reported annually in tropical and subtropical regions. aedes aegypti (linnaeus, 1762), the main vector of dengue, is a domiciliary species with high dispersal and survival capacities and can use various artificial containers as breeding sites. we assessed potential container breeding sites of a. aegypti in the municipality of caxias, maranhão, brazil. | 2012 | 22534987 |
| discriminating lethal concentrations and efficacy of six pyrethroids for control of aedes aegypti in thailand. | establishing baseline insecticide discriminating doses is crucial in accurately determining susceptibility status and changing temporal patterns of physiological response in mosquito populations. pyrethroids are the predominant chemicals used for controlling adult aedes aegypti and ae. albopictus, both vectors of dengue viruses, in thailand. presently, only 2 pyrethroids, permethrin and lambda-cyhalothrin, have published diagnostic dose rates for monitoring ae. aegypti. this study established th ... | 2012 | 22533081 |
| high-throughput pcr assays to monitor wolbachia infection in the dengue mosquito (aedes aegypti) and drosophila simulans. | we have developed and validated two new fluorescence-based pcr assays to detect the wolbachia wmel strain in aedes aegypti and the wri and wau strains in drosophila simulans. the new assays are accurate, informative, and cost-efficient for large-scale wolbachia screening. | 2012 | 22522691 |
| genetic structure and phylogeography of aedes aegypti, the dengue and yellow-fever mosquito vector in bolivia. | between the 16th and 18th centuries, aedes aegypti (diptera: culicidae), a mosquito native to africa, invaded the americas, where it was successively responsible for the emergence of yellow fever (yf) and dengue (den). the species was eradicated from numerous american countries in the mid-20th century, but re-invaded them in the 1970s and 1980s. little is known about the precise identities of ae. aegypti populations which successively thrived in south america, or their relation with the epidemio ... | 2012 | 22522103 |
| high-resolution crystal structure of fkbp12 from aedes aegypti. | dengue is one of the most infectious viral diseases prevalent mainly in tropical countries. the virus is transmitted by aedes species of mosquito, primarily aedes aegypti. dengue remains a challenging drug target for years as the virus eludes the immune responses. currently, no vaccines or antiviral drugs are available for dengue prevention. previous studies suggested that the immunosuppressive drug fk506 shows antimalarial activity, and its molecular target, fk506-binding protein (fkbp), was id ... | 2012 | 22517662 |
| the efficacy of a chitin synthesis inhibitor against field populations of organophosphate-resistant aedes aegypti in brazil. | the mosquito aedes aegypti is the main focus of dengue control campaigns. because of widespread resistance against conventional chemical insecticides, chitin synthesis inhibitors (csis) are considered control alternatives. we evaluated the resistance status of four brazilian ae. aegypti populations to both the organophosphate temephos and the pyrethroid deltamethrin, which are used in brazil to control larvae and adults, respectively. all vector populations exhibited high levels of temephos resi ... | 2012 | 22510835 |
| using bacteria to treat diseases. | mosquito-borne diseases such as malaria and dengue fever result in significant morbidity and mortality in developing countries. vector control is often the most effective strategy to prevent disease transmission and novel methods are required to complement existing insecticide-based strategies. biological control uses natural predators or pathogens to kill mosquitoes or reduce their capacity to transmit disease. bacteria such as wolbachia have been proposed to have the potential to provide effec ... | 2012 | 22500583 |
| dengue vectors and their spatial distribution. | the distribution of dengue vectors, ae. aegypti and ae. albopictus, is affected by climatic factors. in addition, since their life cycles are well adapted to the human environment, environmental changes resulting from human activity such as urbanization exert a great impact on vector distribution. the different responses of ae. aegypti and ae albopictus to various environments result in a difference in spatial distribution along north-south and urban-rural gradients, and between the indoors and ... | 2011 | 22500133 |
| dengue, urbanization and globalization: the unholy trinity of the 21(st) century. | dengue is the most important arboviral disease of humans with over half of the world's population living in areas of risk. the frequency and magnitude of epidemic dengue have increased dramatically in the past 40 years as the viruses and the mosquito vectors have both expanded geographically in the tropical regions of the world. there are many factors that have contributed to this emergence of epidemic dengue, but only three have been the principal drivers: 1) urbanization, 2) globalization and ... | 2011 | 22500131 |
| dispersal of male aedes aegypti in a coastal village in southern mexico. | most aedes aegypti dispersal studies have focused on females because of their central role in dengue virus transmission. only a few mark-release-recapture (mrr) studies provided insights into male ae. aegypti dispersal. to fill this knowledge gap, we conducted five male ae. aegypti mrr experiments in a coastal village in southern mexico. small and large male cohorts were marked with fluorescent dusts, released outside buildings, and recaptures were carried out by using backpack aspirators. recap ... | 0 | 22492152 |
| evidence of polyandry for aedes aegypti in semifield enclosures. | female aedes aegypti are assumed to be primarily monandrous (i.e., mate only once in their lifetime), but true estimates of mating frequency have not been determined outside the laboratory. to assess polyandry in ae. aegypti with first-generation progeny from wild mosquitoes, stable isotope semen-labeled males ((15)n or (13)c) were allowed to mate with unlabeled females in semifield enclosures (22.5 m(3)) in a dengue-endemic area in southern mexico. on average, 14% of females were positive for b ... | 0 | 22492148 |
| comparing statistical models to predict dengue fever notifications. | dengue fever (df) is a serious public health problem in many parts of the world, and, in the absence of a vaccine, disease surveillance and mosquito vector eradication are important in controlling the spread of the disease. df is primarily transmitted by the female aedes aegypti mosquito. we compared two statistical models that can be used in the surveillance and forecast of notifiable infectious diseases, namely, the autoregressive integrated moving average (arima) model and the knorr-held two- ... | 2012 | 22481978 |
| pinpointing p450s associated with pyrethroid metabolism in the dengue vector, aedes aegypti: developing new tools to combat insecticide resistance. | pyrethroids are increasingly used to block the transmission of diseases spread by aedes aegypti such as dengue and yellow fever. however, insecticide resistance poses a serious threat, thus there is an urgent need to identify the genes and proteins associated with pyrethroid resistance in order to produce effective counter measures. in ae. aegypti, overexpression of p450s such as the cyp9j32 gene have been linked with pyrethroid resistance. our aim was to confirm the role of cyp9j32 and other p4 ... | 2012 | 22479665 |
| dengue virus infection of the aedes aegypti salivary gland and chemosensory apparatus induces genes that modulate infection and blood-feeding behavior. | the female aedes aegypti salivary gland plays a pivotal role in bloodmeal acquisition and reproduction, and thereby dengue virus (denv) transmission. it produces numerous immune factors, as well as immune-modulatory, vasodilatory, and anti-coagulant molecules that facilitate blood-feeding. to assess the impact of denv infection on salivary gland physiology and function, we performed a comparative genome-wide microarray analysis of the naïve and denv infection-responsive a. aegypti salivary gland ... | 2012 | 22479185 |
| aedes aegypti saliva enhances dengue virus infection of human keratinocytes by suppressing innate immune responses. | 2012 | 22475758 | |
| detection of chikungunya virus in aedes aegypti during 2011 outbreak in al hodayda, yemen. | in october 2010, the ministry of public health and population reported an outbreak of dengue-like acute febrile illness in al hodayda governorate. by january 2011, a total of 1542 cases had been recorded from 19 of the 26 districts in the governorate with 104 purportedly associated deaths. in response this event, in january 2011 entomological investigations aimed at identifying the primary vector and the epidemic associated etiological agent were carried out. based on the reported cases and the ... | 2012 | 22469818 |
| a community empowerment strategy embedded in a routine dengue vector control programme: a cluster randomised controlled trial. | the non-sustainability of vertically organised dengue vector control programmes led to pleas for changing the emphasis towards community-based strategies. we conducted a cluster randomised controlled trial with 16 intervention and 16 control clusters to test the effectiveness of a community empowerment strategy intertwined with the routine dengue vector control programme in la lisa, havana city, cuba. the intervention included four components on top of routine control: organisation and managemen ... | 2012 | 22465423 |
| aedes aegypti re-emerging in egypt: a review and what should be done? | mosquitoes are main vectors of varieties of pathogenic agents affecting man and animals. there-emergencein aswan and approach of aedesa egypti, the vector of the dengue hemorrhagic fever, yellow fever and chikungunya fever, which are encountered in africa, needs to alert for this public health threat. the presence of dengue and dengue hemorrhagic fever in saudi arabia is another issue. | 2011 | 22435171 |
| biogeography of the two major arbovirus mosquito vectors, aedes aegypti and aedes albopictus (diptera, culicidae), in madagascar. | in the past ten years, the indian ocean region has been the theatre of severe epidemics of chikungunya and dengue. these outbreaks coincided with a high increase in populations of aedes albopictus that outcompete its sister taxon aedes aegypti in most islands sampled. the objective of this work was to update the entomological survey of the two aedes species in the island of madagascar which has to face these arboviroses. | 2012 | 22433186 |
| effect of insecticide resistance on development, longevity and reproduction of field or laboratory selected aedes aegypti populations. | aedes aegypti dispersion is the major reason for the increase in dengue transmission in south america. in brazil, control of this mosquito strongly relies on the use of pyrethroids and organophosphates against adults and larvae, respectively. in consequence, many ae. aegypti field populations are resistant to these compounds. resistance has a significant adaptive value in the presence of insecticide treatment. however some selected mechanisms can influence important biological processes, leading ... | 2012 | 22431967 |
| reciprocal tripartite interactions between the aedes aegypti midgut microbiota, innate immune system and dengue virus influences vector competence. | dengue virus is one of the most important arboviral pathogens and the causative agent of dengue fever, dengue hemorrhagic fever, and dengue shock syndrome. it is transmitted between humans by the mosquitoes aedes aegypti and aedes albopictus, and at least 2.5 billion people are at daily risk of infection. during their lifecycle, mosquitoes are exposed to a variety of microbes, some of which are needed for their successful development into adulthood. however, recent studies have suggested that th ... | 2012 | 22413032 |
| complex phenotypes in mosquitoes and mice associated with neutralization escape of a dengue virus type 1 monoclonal antibody. | denv1-e106 is a monoclonal antibody (mab) with strong neutralizing activity against all five denv-1 genotypes and therapeutic activity in mice. here, we evaluated the potential for denv-1 to escape neutralization by denv1-e106. a single mutation in domain iii of the envelope protein (t329a) emerged, which conferred resistance to denv1-e106. however, the t329a variant virus had differing phenotypes in vitro and in vivo with attenuation in cell culture yet increased infectivity in aedes aegypti mo ... | 2012 | 22406169 |
| mosquitocidal activity of solanum xanthocarpum fruit extract and copepod mesocyclops thermocyclopoides for the control of dengue vector aedes aegypti. | the present study was carried out on solanum xanthocarpum fruit extract and copepods mesocyclops thermocyclopoides, which were assessed for the control of dengue vector, aedes aegypti, under laboratory conditions. the medicinal plants were collected from the outskirts of bharathiar university, coimbatore, tamil nadu, india. the shade-dried fruit materials were extracted by employing the soxhlet apparatus with methanol (organic solvent) 8 h and the extracts were filtered through a buchner funnel ... | 2012 | 22398832 |
| effect of moringa oleifera flower extract on larval trypsin and acetylcholinesterase activities in aedes aegypti. | aedes aegypti control is crucial to reducing dengue fever. aedes aegypti larvae have developed resistance to organophosporous insecticides and the use of natural larvicides may help manage larval resistance by increasing elements in insecticide rotation programs. here, we report on larvicidal activity of moringa oleifera flower extract against a. aegypti l(1), l(2), l(3), and l(4) as well as the effect of flower extract on gut trypsin and whole-larval acetylcholinesterase from l(4.) in addition, ... | 2012 | 22392801 |
| strain variation in the transcriptome of the dengue fever vector, aedes aegypti. | studies of transcriptome dynamics provide a basis for understanding functional elements of the genome and the complexity of gene regulation. the dengue vector mosquito, aedes aegypti, exhibits great adaptability to diverse ecological conditions, is phenotypically polymorphic, and shows variation in vectorial capacity to arboviruses. previous genome sequencing showed richness in repetitive dna and transposable elements that can contribute to genome plasticity. population genetic studies revealed ... | 2012 | 22384387 |
| the relative importance of innate immune priming in wolbachia-mediated dengue interference. | the non-virulent wolbachia strain wmel and the life-shortening strain wmelpop-cla, both originally from drosophila melanogaster, have been stably introduced into the mosquito vector of dengue fever, aedes aegypti. each of these wolbachia strains interferes with viral pathogenicity and/or dissemination in both their natural drosophila host and in their new mosquito host, and it has been suggested that this virus interference may be due to host immune priming by wolbachia. in order to identify asp ... | 2012 | 22383881 |
| evaluation of the human igg antibody response to aedes albopictus saliva as a new specific biomarker of exposure to vector bites. | the spread of aedes albopictus, a vector for re-emergent arbovirus diseases like chikungunya and dengue, points up the need for better control strategies and new tools to evaluate transmission risk. human antibody (ab) responses to mosquito salivary proteins could represent a reliable biomarker for evaluating human-vector contact and the efficacy of control programs. | 2012 | 22363823 |
| insecticide resistance in the dengue vector aedes aegypti from martinique: distribution, mechanisms and relations with environmental factors. | dengue is an important mosquito borne viral disease in martinique island (french west indies). the viruses responsible for dengue are transmitted by aedes aegypti, an indoor day-biting mosquito. the most effective proven method for disease prevention has been by vector control by various chemical or biological means. unfortunately insecticide resistance has already been observed on the island and recently showed to significantly reduce the efficacy of vector control interventions. in this study, ... | 2012 | 22363529 |
| changing domesticity of aedes aegypti in northern peninsular malaysia: reproductive consequences and potential epidemiological implications. | the domestic dengue vector aedes aegypti mosquitoes breed in indoor containers. however, in northern peninsular malaysia, they show equal preference for breeding in both indoor and outdoor habitats. to evaluate the epidemiological implications of this peridomestic adaptation, we examined whether ae. aegypti exhibits decreased survival, gonotrophic activity, and fecundity due to lack of host availability and the changing breeding behavior. | 2012 | 22363516 |
| identifying insecticide resistance genes in mosquito by combining aflp genome scans and 454 pyrosequencing. | aflp-based genome scans are widely used to study the genetics of adaptation and to identify genomic regions potentially under selection. however, this approach usually fails to detect the actual genes or mutations targeted by selection owing to the difficulties of obtaining dna sequences from aflp fragments. here, we combine classical aflp outlier detection with 454 sequencing of aflp fragments to obtain sequences from outlier loci. we applied this approach to the study of resistance to bacillus ... | 2012 | 22348648 |
| climate-based models for understanding and forecasting dengue epidemics. | dengue dynamics are driven by complex interactions between human-hosts, mosquito-vectors and viruses that are influenced by environmental and climatic factors. the objectives of this study were to analyze and model the relationships between climate, aedes aegypti vectors and dengue outbreaks in noumea (new caledonia), and to provide an early warning system. | 2012 | 22348154 |
| genetic mapping a meiotic driver that causes sex ratio distortion in the mosquito aedes aegypti. | an endogenous meiotic driver in the dengue and yellow fever vector mosquito aedes aegypti can cause highly male-biased sex ratio distortion in crosses from suitable genetic backgrounds. we previously selected a strain that carries a strong meiotic drive gene (d) linked with the male-determining allele (m) on chromosome 1 in a. aegypti. here, we performed segregation analysis of the m(d) locus among backcross (bc(1)) progeny from a driver male and drive-sensitive females. assessment of sex ratios ... | 2012 | 22308303 |
| insecticide susceptibility of the dengue vector, aedes aegypti (l.) in metropolitan bangkok. | mosquito larvae were collected from the houses of dengue infected patients in bangkok, thailand from 55 sites (36 out of the 50 districts of metropolitan bangkok). aedes aegypti larvae were tested against temephos using who bioassay techniques. adult mosquitoes were tested for susceptibility to permethrin, deltamethrin, cyfluthrin, malathion and ddt using who diagnostic doses. most of the larvae tested were susceptible to temephos. only few specimens were resistant to temephos. most adult mosqui ... | 2011 | 22299463 |
| physiological and morphological aspects of aedes aegypti developing larvae: effects of the chitin synthesis inhibitor novaluron. | population control of the dengue vector mosquito, aedes aegypti, is difficult due to many reasons, one being the development of resistance to neurotoxic insecticides employed. the biosynthesis of chitin, a major constituent of insect cuticle, is a novel target for population control. novaluron is a benzoylphenylurea (bpu) that acts as a chitin synthesis inhibitor, already used against mosquitoes. however, information regarding bpu effects on immature mosquito stages and physiological parameters ... | 2012 | 22291942 |
| aedes albopictus and the reemergence of dengue. | dengue is a vector-borne disease that is estimated to affect millions of individuals each year in tropical and subtropical areas, and it is reemerging in areas that have been disease-free for relatively long periods of time. in this issue of the journal, peng et al. report on a dengue outbreak in a city in southern china that had been disease-free for more than two decades. the infection, which was due to serotype 1, was introduced by a traveler from south-east asia and transmitted by aedes albo ... | 2012 | 22272602 |
| aedes aegypti egg counting system. | new monitoring methods of dengue vector and evaluation of public policies on dengue control are major concerns for several tropical countries. drawback on monitoring methods base on oviposition surveys are the counting process of mosquito eggs, information store and analysis. here we present a new automated egg counting system for remote aedes aegypti population survey. the system is base on an optical scanning platform, a man-machine interface, and a software for mosquitoes eggs counting. acqui ... | 2011 | 22255902 |
| testing the effectiveness of community-based dengue vector control interventions using semiparametric mixed models. | to evaluate the results obtained though intersectoral coordination and community empowerment in one study carried out during 6 years in playa municipality, cuba. | 2012 | 22239179 |
| genetics and morphology of aedes aegypti (diptera: culicidae) in septic tanks in puerto rico. | dengue viruses, primarily transmitted by the mosquito aedes aegypti (l.), affect an estimated 50-100 million people yearly. traditional approaches to control mosquito population numbers, such as the use of pesticides, have had only limited success. atypical mosquito behavior may be one reason why current vector control efforts have been less efficacious than expected. in puerto rico, for example, adult ae. aegypti have been observed emerging from septic tanks. interestingly, adults emerging from ... | 0 | 22238867 |
| larvicidal efficacy of the citrus limetta peel extracts against indian strains of anopheles stephensi liston and aedes aegypti l. | the extracts from the peels of citrus limetta were prepared using hexane and petroleum ether as the solvents. the larvicidal potential of each extract was assessed against dengue fever vector, aedes aegypti, and malarial vector, anopheles stephensi, by evaluating the toxicity effects on early fourth instars. both the extracts were found effective against both the species. the bioassay with hexane extracts resulted in lc(50) values of 132.45 and 96.15 ppm against a. stephensi and a. aegypti, resp ... | 2012 | 22231268 |
| larvicidal and ovicidal properties of leaf and seed extracts of delonix elata (l.) gamble (family: fabaceae) against malaria (anopheles stephensi liston) and dengue (aedes aegypti linn.) (diptera: culicidae) vector mosquitoes. | mosquito-borne diseases with an economic impact create loss in commercial and labor outputs, particularly in countries with tropical and subtropical climates. mosquito control is facing a threat because of the emergence of resistance to synthetic insecticides. extracts from plants may be alternative sources of mosquito control agents because they constitute a rich source of bioactive compounds that are biodegradable into nontoxic products and potentially suitable for use to control mosquitoes. i ... | 2012 | 22231265 |
| dengue virus infection in renal allograft recipients: a case series during 2010 outbreak. | dengue virus infection is an emerging global threat caused by arbovirus, a virus from flaviridiae family, which is transmitted by mosquitoes, aedes aegypti and aedes albopictus. renal transplant recipients who live in the endemic zones of dengue infection or who travel to an endemic zone could be at risk of this infection. despite multiple epidemics and a high case fatality rate in the southeast asian region, only a few cases of dengue infection in renal transplant recipients have been reported. ... | 2011 | 22212524 |
| [abundance and distribution of aedes aegypti (diptera: culicidae), and dengue dispersion in guasave sinaloa, mexico]. | dengue is an important disease that affects humans, and is transmitted by a. aegypti. during 2006, a total of 477 cases of hemorrhagic dengue, and 1 510 of classic dengue were recorded in sinaloa. due to this high impact, a study on insect abundance and distribution, as well as their relationship with dengue dispersion, was carried out from april 2008 to march 2009 in guasave, sinaloa. the study included a total of six sectors in the city, considering 16 colonies; besides, 96 traps were distribu ... | 2011 | 22208078 |
| novel, meso-substituted cationic porphyrin molecule for photo-mediated larval control of the dengue vector aedes aegypti. | control of the mosquito vector population is the most effective strategy currently available for the prevention of dengue fever and the containment of outbreaks. photo-activated oxidants may represent promising tools for developing effective, safe and ecofriendly novel larvicides. the purpose of this study was to evaluate the potential of the synthetic meso-substituted porphyrin meso-tri(n-methylpyridyl), meso-mono(n-tetradecylpyridyl)porphine (c14) as a photoactivatable larvicide against the de ... | 2011 | 22206031 |
| Population Dynamics of Aedes aegypti and Dengue as Influenced by Weather and Human Behavior in San Juan, Puerto Rico. | Previous studies on the influence of weather on Aedes aegypti dynamics in Puerto Rico suggested that rainfall was a significant driver of immature mosquito populations and dengue incidence, but mostly in the drier areas of the island. We conducted a longitudinal study of Ae. aegypti in two neighborhoods of the metropolitan area of San Juan city, Puerto Rico where rainfall is more uniformly distributed throughout the year. We assessed the impacts of rainfall, temperature, and human activities on ... | 2011 | 22206021 |
| the entomopathogenic fungus beauveria bassiana activate toll and jak-stat pathway-controlled effector genes and anti-dengue activity in aedes aegypti. | here we investigated the effect of beauveria bassiana infection on the survival of aedesaegypti mosquitoes and the modulation of their susceptibility to dengue virus infection. application of b. bassiana caused a reduction in the life span of a. aegypti and hindered dengue virus replication in the mosquito midgut. fungus infection induced the expression a variety anti-microbial and dengue virus restriction factor genes. transient reverse genetic analyses showed that the jak-stat pathway is impli ... | 2011 | 22198333 |
| Constraints on the use of lifespan-shortening Wolbachia to control dengue fever. | Dengue fever, a viral disease spread by the mosquito Aedes aegypti, affects 50-100 million people a year in many tropical countries. Because the virus must incubate within mosquito hosts for two weeks before being able to transmit the infection, shortening the lifespan of mosquitoes may curtail dengue transmission. We developed a continuous time reaction-diffusion model of the spatial spread of Wolbachia through a population of A. aegypti. This model incorporates the lifespan-shortening effects ... | 2011 | 22192469 |
| characterization of bacillus thuringiensis isolates with potential for control of aedes aegypti (linnaeus, 1762) (diptera: culicidae). | aedes aegypti (linnaeus) is the vector of dengue virus in brazil. bioinsecticides based on bacillus thuringiensis have shown satisfactory results in the control of diptera, due to the production of proteins called cry and cyt. the aim of the present study was to select b. thuringiensis isolates carrying the cry and cyt genes, which are efficient in the control of ae. aegypti. a collection of 27 isolates of b. thuringiensis, derived from various regions in brazil, was evaluated using selective bi ... | 2011 | 22178674 |
| comparison of wing geometry data and genetic data for assessing the population structure of aedes aegypti. | aedes aegypti is the most important vector of dengue viruses in tropical and subtropical regions. because vaccines are still under development, dengue prevention depends primarily on vector control. population genetics is a common approach in research involving ae. aegypti. in the context of medical entomology, wing morphometric analysis has been proposed as a strong and low-cost complementary tool for investigating population structure. therefore, we comparatively evaluated the genetic and phen ... | 2012 | 22178147 |
| larvicidal efficacy of adhatoda vasica (l.) nees against the bancroftian filariasis vector culex quinquefasciatus say and dengue vector aedes aegypti l. in in vitro condition. | the larvicidal activities of methanolic fractions from adhatoda vasica leaf extracts were investigated against the bancroftian filariasis vector culex quinquefasciatus and dengue vector aedes aegypti. the results indicated that the mortality rates was high at 100, 150, 200 and 250 ppm of methanol extract of fractions iii with r (f) value 0.67 and methanol extract of fraction v with r (f) value 0.64 of a. vasica against all the larval instars of c. quinquefasciatus and a. aegypti. the result of l ... | 2012 | 22167370 |
| spatial stability of adult aedes aegypti populations. | vector control programs could be more efficient by identifying the location of highly productive sites of aedes aegypti. this study explored if the number of female adults of ae. aegypti in bg-sentinel traps was clustered and if their spatial distribution changed in time in two neighborhoods in san juan, puerto rico. traps were uniformly distributed across each neighborhood (130 m from each other), and samples were taken every 3 weeks. global and local spatial autocorrelations were explored. spa ... | 0 | 22144449 |
| robust heat-inducible gene expression by two endogenous hsp70-derived promoters in transgenic aedes aegypti. | aedes aegypti is an important vector of the viruses that cause dengue fever, dengue haemorrhagic fever and yellow fever. reverse genetic approaches to the study of gene function in this mosquito have been limited by the lack of a robust inducible promoter to allow precise temporal control over a protein-encoding or hairpin rna transgene. likewise, investigations into the molecular and biochemical basis of vector competence would benefit from the ability to activate an antipathogen molecule at sp ... | 2011 | 22142225 |
| Chemical composition and larvicidal activity of essential oil from Mentha spicata (Linn.) against three mosquito species. | Mosquitoes are blood-feeding insects and serve as the most important vectors for spreading human diseases such as malaria, yellow fever, dengue fever, and filariasis. The continued use of synthetic insecticides has resulted in resistance in mosquitoes. Synthetic insecticides are toxic and affect the environment by contaminating soil, water, and air, and then natural products may be an alternative to synthetic insecticides because they are effective, biodegradable, eco-friendly, and safe to envir ... | 2011 | 22139403 |
| larval development of aedes aegypti and aedes albopictus in peri-urban brackish water and its implications for transmission of arboviral diseases. | aedes aegypti (linnaeus) and aedes albopictus skuse mosquitoes transmit serious human arboviral diseases including yellow fever, dengue and chikungunya in many tropical and sub-tropical countries. females of the two species have adapted to undergo preimaginal development in natural or artificial collections of freshwater near human habitations and feed on human blood. while there is an effective vaccine against yellow fever, the control of dengue and chikungunya is mainly dependent on reducing f ... | 2011 | 22132243 |
| dengue-1 virus clade replacement in thailand associated with enhanced mosquito transmission. | dengue viruses (denv) are characterized by extensive genetic diversity and can be organized in multiple, genetically distinct lineages that arise and die out on a regular basis in regions where dengue is endemic. a fundamental question for understanding denv evolution is the relative extent to which stochastic processes (genetic drift) and natural selection acting on fitness differences among lineages contribute to lineage diversity and turnover. here, we used a set of recently collected and arc ... | 2011 | 22130539 |
| assessing the impact of density dependence in field populations of aedes aegypti. | although many laboratory studies of intra-specific competition have been conducted with ae. aegypti, there have been few studies in natural environments and none that examined density dependence in natural containers at normal field densities. additionally, current mathematical models that predict ae. aegypti population dynamics lack empirically-based functions for density-dependence. we performed field experiments in tapachula, mexico, where dengue is a significant public health concern. twenty ... | 2011 | 22129401 |
| programmed autophagy in the fat body of aedes aegypti is required to maintain egg maturation cycles. | autophagy plays a pivotal role by allowing cells to recycle cellular components under conditions of stress, starvation, development and cancer. in this work, we have demonstrated that programmed autophagy in the mosquito fat body plays a critical role in maintaining of developmental switches required for normal progression of gonadotrophic cycles. mosquitoes must feed on vertebrate blood for their egg development, with each gonadotrophic cycle being tightly coupled to a separate blood meal. as a ... | 2011 | 22125592 |
| evaluation of students' knowledge as a contribution to dengue control programs. | this study describes a survey (n=700) carried out in 14 elementary schools in the municipality of caxias, state of maranhão, brazil. the survey was conducted between july and december 2007 in schools from seven neighborhoods on the outskirts of the western part of the municipality, where for the past three years high densities of immature aedes aegypti mosquitoes have been recorded. the students' knowledge of dengue, its vector, and disease prevention was evaluated by targeted questionnaires. th ... | 2011 | 22124817 |
| wolbachia induces reactive oxygen species (ros)-dependent activation of the toll pathway to control dengue virus in the mosquito aedes aegypti. | wolbachia are maternally transmitted symbiotic bacteria that can spread within insect populations because of their unique ability to manipulate host reproduction. when introduced to nonnative mosquito hosts, wolbachia induce resistance to a number of human pathogens, including dengue virus (denv), plasmodium, and filarial nematodes, but the molecular mechanism involved is unclear. in this study, we have deciphered how wolbachia infection affects the aedes aegypti host in inducing resistance to d ... | 2011 | 22123956 |
| wolbachia strain wmel induces cytoplasmic incompatibility and blocks dengue transmission in aedes albopictus. | wolbachia inherited bacteria are able to invade insect populations using cytoplasmic incompatibility and provide new strategies for controlling mosquito-borne tropical diseases, such as dengue. the overreplicating wmelpop strain was recently shown to strongly inhibit the replication of dengue virus when introduced into aedes aegypti mosquitoes, as well as to stimulate chronic immune up-regulation. here we show that stable introduction of the wmel strain of drosophila melanogaster into aedes albo ... | 2011 | 22123944 |
| modeling spatio-temporal risk changes in the incidence of dengue fever in saudi arabia: a geographical information system case study. | the aim of this study was to use geographical information systems to demonstrate the dengue fever (df) risk on a monthly basis in jeddah, saudi arabia with the purpose to provide documentation serving to improve surveillance and monitor the aedes aegypti mosquito vector. getis-ord gi* statistics and a frequency index covering a five-year period (2006-2010) were used to map df and model the risk spatio-temporally. the results show that monthly hotspots were mainly concentrated in central jeddah d ... | 2011 | 22109865 |
| global cross-talk of genes of the mosquito aedes aegypti in response to dengue virus infection. | the mosquito aedes aegypti is the primary vector of dengue virus (denv) infection in humans, and denv is the most important arbovirus across most of the subtropics and tropics worldwide. the early time periods after infection with denv define critical cellular processes that determine ultimate success or failure of the virus to establish infection in the mosquito. | 2011 | 22102922 |
| challenges in estimating insecticide selection pressures from mosquito field data. | insecticide resistance has the potential to compromise the enormous effort put into the control of dengue and malaria vector populations. it is therefore important to quantify the amount of selection acting on resistance alleles, their contributions to fitness in heterozygotes (dominance) and their initial frequencies, as a means to predict the rate of spread of resistance in natural populations. we investigate practical problems of obtaining such estimates, with particular emphasis on mexican p ... | 2011 | 22069506 |
| a novel herbal formulation against dengue vector mosquitoes aedes aegypti and aedes albopictus. | the objective of this study was to develop a herbal formulation to control dengue vector mosquitoes. ponneem, a novel herbal formulation prepared using the oils of neem (azadirachta indica), karanj (pongamia glabra) and their extracts, was tested for larvicidal, ovicidal and oviposition deterrent activities against aedes aegypti and aedes albopictus at 1, 0.5, 0.3 and 0.1 ppm concentrations. cent percent larvicidal and ovicidal activities were observed at 0.1 ppm in the two mosquito species unde ... | 2011 | 22042505 |
| Factors influencing the seasonal abundance of Aedes (Stegomyia) aegypti and the control strategy of dengue and dengue haemorrhagic fever in Thanlyin Township, Yangon City, Myanmar. | From June 2006 to May 2007, mosquito surveys were conducted in Thanlyin Township, Yangon City, Myanmar, to determine factors influencing the abundance of Aedes aegypti (Stegomyia aegypti) during the rainy season. Both the biological and environmental factors were included in this study. Increase in the hatchability of egg, larval survival rate, the shortened larval life-span and increased pupation rates supplemented by rainfall (i.e. continuous flooding of the containers, stimulate the ... | 2011 | 22041749 |
| optimal timing of insecticide fogging to minimize dengue cases: modeling dengue transmission among various seasonalities and transmission intensities. | dengue infection is endemic in many regions throughout the world. while insecticide fogging targeting the vector mosquito aedes aegypti is a major control measure against dengue epidemics, the impact of this method remains controversial. a previous mathematical simulation study indicated that insecticide fogging minimized cases when conducted soon after peak disease prevalence, although the impact was minimal, possibly because seasonality and population immunity were not considered. periodic out ... | 2011 | 22039560 |
| field performance of engineered male mosquitoes. | dengue is the most medically important arthropod-borne viral disease, with 50-100 million cases reported annually worldwide. as no licensed vaccine or dedicated therapy exists for dengue, the most promising strategies to control the disease involve targeting the predominant mosquito vector, aedes aegypti. however, the current methods to do this are inadequate. various approaches involving genetically engineered mosquitoes have been proposed, including the release of transgenic sterile males. how ... | 2011 | 22037376 |
| [knowledge, attitudes and community practice during an outbreak of dengue in a town in colombia, 2010]. | 17 cases of dengue were reported from the town of el playón (7°28'15"-n/73°12'00"-w/altitude 510 masl) during epidemiological study weeks 5-6 and 12-13/2010. the santander department's health secretariat sought outbreak investigation and community knowledge-attitudes-practice (kap) assessment on 16-4-2010 concerning a dengue fever outbreak in the town after an epidemiological surveillance committee had met; this was to strengthen local action regarding aedes aegypti vector promotion-prevention-c ... | 2011 | 22031003 |