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interferences in match kernels.we consider the design of an image representation that embeds and aggregates a set of local descriptors into a single vector. popular representations of this kind include the bag-of-visual-words, the fisher vector and the vlad. when two such image representations are compared with the dot-product, the image-to-image similarity can be interpreted as a match kernel. in match kernels, one has to deal with interference, i.e., with the fact that even if two descriptors are unrelated, their matching s ...201727723578
breast cancer detection in a screening population: comparison of digital mammography, computer-aided detection applied to digital mammography and breast ultrasound.we aimed to compare the detection of breast cancer using full-field digital mammography (ffdm), ffdm with computer-aided detection (ffdm+cad), ultrasound (us), and ffdm+cad plus us (ffdm+cad+us), and to investigate the factors affecting cancer detection.201627721882
hematologic counts as predictors of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.aneurysmal subarachnoid hemorrhage (sah) is associated with high morbidity and mortality, but currently no single clinical method or ancillary test can reliably predict which subset of patients will develop delayed cerebral ischemia (dci). the aim of this study was to find hematologic derangements and clinical factors present during the first 7 days after bleeding that could help identify patients at risk for development of dci.201727718411
predictors of delayed cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage with asymptomatic angiographic vasospasm on admission.risk of delayed cerebral ischemia (dci) in patients with aneurysmal subarachnoid hemorrhage (asah) with asymptomatic angiographic vasospasm on admission is unclear in the literature. the goal of this study is to identify predictors of clinical dci in this group of patients.201727717776
electrophysiological activity of the pharyngoesophageal transition of total laryngectomees.to determine the association of the electrophysiological activity of the pharyngoesophageal transition with tracheoesophageal speech proficiency in total laryngectomees.201727716924
establishment of two data mining models of lung cancer screening based on three gene promoter methylations combined with telomere damage.to identify the significance of a support vector machine (svm) model and a decision tree (dt) model for the diagnosis of lung cancer combined with the detection of fragile histidine triad (fhit), ras association domain family 1 (rassf1a) and cyclin-dependent kinase inhibitor 2a (p16) promoter methylation levels and relative telomere length (rtl) of white blood cells from peripheral blood dna.201727716889
genetic, histochemical and biochemical studies on goat tse cases from cyprus.scrapie and bovine spongiform encephalopathy (bse) are transmissible spongiform encephalopathies (tse's) affecting sheep and goats. susceptibility of goats to scrapie is influenced by polymorphisms of the prion protein gene (prnp) of the host. five polymorphisms are associated with reduced susceptibility to tse's. in the study presented here caprine samples from a scrapie eradication program on cyprus were genotyped and further characterized using biorad tesee rapid test, histological, immunohis ...201627716411
spin-echo echo-planar imaging mr elastography versus gradient-echo mr elastography for assessment of liver stiffness in children and young adults suspected of having liver disease.purpose to compare two-dimensional (2d) gradient-recalled echo (gre) and 2d spin-echo (se) echo-planar imaging (epi) magnetic resonance (mr) elastography for measurement of hepatic stiffness in pediatric and young adult patients suspected of having liver disease. materials and methods in this institutional review board-approved, hipaa-compliant study, 58 patients underwent both 2d gre and 2d se-epi mr elastography at 1.5 t during separate breath holds. liver stiffness (mean of means; in kilopasc ...201727715486
characteristics of infarction after encephaloduroarteriosynangiosis in young patients with moyamoya disease.objective young patients with moyamoya disease can exhibit infarction after revascularization surgery. this analysis of the characteristics of infarction after encephaloduroarteriosynangiosis (edas) in young patients with moyamoya disease was undertaken in an effort to elucidate the infarction mechanism. methods the authors retrospectively collected clinical information and reviewed pre- and postoperative mri studies from cases involving patients younger than 18 years who underwent edas for the ...201727715484
kir repertory in patients with hematopoietic diseases and healthy family members.since the discovery of specific histocompatibility, literature has associated genes involved in the immune response, like the human leucocyte antigen (hla), with a better prognosis in transplantation. however, other non-hla genes may also influence the immune process, such as the genes encoding the immunoglobulin-like receptors of natural killer cells (kirs). the discovery that nk cell kir receptors interact with conservative epitopes (c1, c2, bw4) presented in hla class i molecules that are gen ...201627708784
genomic characteristics behind the spread of bacteremic group a streptococcus type emm89 in finland, 2004-2014.many countries worldwide have reported increasing numbers of emm89 group a streptococcus (gas) infections during last decade. pathogen genetic factors linked to this increase need assessment.201627707808
different perspectives: spatial ability influences where individuals look on a timed spatial test.learning in anatomy can be both spatially and visually complex. pedagogical investigations have begun exploration as to how spatial ability may mitigate learning. emerging hypotheses suggests individuals with higher spatial reasoning may attend to images differently than those who are lacking. to elucidate attentional patterns associated with different spatial ability, eye movements were measured in individuals completing a timed electronic mental rotation test (emrt). the emrt was based on the ...201727706927
electrical and thermal transport properties of the electron-doped cuprate sm2-x ce x cuo4-y system.electrical and thermal transport measurements were performed on thin films of the electron-doped superconductor sm2-x ce x cuo4-y (x  =  0.13  -  0.19) in order to study the evolving nature of the charge carriers from the under-doped to over-doped regime. a temperature versus cerium content (t  -  x) phase diagram has been constructed from the electrical transport measurements, yielding a superconducting region similar to that found for other electron-doped superconductors. thermopower measureme ...201627705951
cobb-1 versus cobb-to-cobb anterior fusion for adolescent idiopathic scoliosis lenke 5c curves: a radiological comparative study.anterior fusion is a well-established procedure for the treatment of lenke 5c adolescent idiopathic scoliosis (ais). this retrospective study aimed to assess preoperative and postoperative radiographic differences between the conventional anterior fusion and anterior short fusions (asf) in lenke 5c ais.201727704285
mini-percutaneous nephrolithotomy for stones in anomalous-kidneys: a prospective study.to evaluate safety and efficacy of minipercutaneous nephrolithotomy (mini-pnl) in management of stones in different types of renal anomalies. patients with stones ≥2 cm or swl-resistant stones in anomalous-kidneys treated by mini-pnl between march 2010 and september 2012 were included prospectively. mini-pnl was done under regional anesthesia in prone position with fluoroscopic guidance through 18 fr sheath using semirigid ureteroscope (8.5/11.5 fr) and pneumatic lithotripter. all patients were ...201727704184
occurrence and timing of complications following traumatic dental injuries: a retrospective study in a dental trauma department.this study explores the pattern of complications occurrence resulting from traumatic dental injuries, the relation of this pattern to the number of years from the time of the injury to its first diagnosis, and other contributing characteristics such as root development and trauma characteristic.201627703612
small hepatocyte-like progenitor cells may be a hedgehog signaling pathway-controlled subgroup of liver stem cells.the present study aimed to investigate the expression levels of components of the hedgehog signaling pathway (hh) during the proliferation of a liver stem cell subgroup, namely small hepatocyte-like progenitor cells (shpcs). retrorsine-treated fisher 344 rats underwent a partial hepatectomy (ph) to induce the proliferation of shpcs, after which reverse transcription-polymerase chain reaction (pcr), quantitative pcr, immunohistochemistry and western blot analysis were performed to analyze the exp ...201627703504
organizing and managing your research: a practical guide for postgraduates renata phelps organizing and managing your research: a practical guide for postgraduates , kath fisher and allan ellis sage edition: first 304 £19.99 1412920643 1412920643 [formula: see text].this is a first edition of a new book designed to help postgraduate students manage and organise their research projects. as a current phd student and supervisor of undergraduate and postgraduate students, i was intrigued to see what this book could offer.200827702011
validation of the applied biosystems rapidfinder shiga toxin-producing e. coli (stec) detection workflow.the applied biosystems™ rapidfinder™ stec detection workflow (thermo fisher scientific) is a complete protocol for the rapid qualitative detection of escherichia coli (e. coli) o157:h7 and the "big 6" non-o157 shiga-like toxin-producing e. coli (stec) serotypes (defined as serogroups: o26, o45, o103, o111, o121, and o145). the rapidfinder stec detection workflow makes use of either the automated preparation of pcr-ready dna using the applied biosystems prepseq™ nucleic acid extraction kit in con ...201627697104
factors affecting outcome in poor grade subarachnoid haemorrhage: an institutional study.poor grade subarachnoid hemorrhage (sah) is usually associated with unfavorable outcomes and optimal management is deemed complicated. most centres follow an expectant management strategy or a less aggressive approach till patients improve to good clinical grades. this approach has been associated with higher mortality and morbidity. however, not all patients with poor clinical condition fare badly. identification and early aggressive management of this select group of patients may lead to favor ...201727695539
resampling-based multiple comparison procedure with application to point-wise testing with functional data.in this paper we describe a coherent multiple testing procedure for correlated test statistics such as are encountered in functional linear models. the procedure makes use of two different p-value combination methods: the fisher combination method and the šidák correction-based method. p-values for fisher's and šidák's test statistics are estimated through resampling to cope with the correlated tests. building upon these two existing combination methods, we propose the smallest p-value as a new ...201527695383
local vs general anaesthesia in the development of neurosensory disturbances after mandibular third molars extraction: a retrospective study of 534 cases.the choice of the anaesthetic modality is one of the primary steps during planning of third molar surgery. the aim of the present study was to compare the risk of developing neurological injures of the inferior alveolar nerve (ian) and lingual nerve (ln) in patients treated for wisdom teeth removal under general anaesthesia (ga) with a group treated under local anaesthesia (la).201627694783
pornography classification: the hidden clues in video space-time.as web technologies and social networks become part of the general public's life, the problem of automatically detecting pornography is into every parent's mind - nobody feels completely safe when their children go online. in this paper, we focus on video-pornography classification, a hard problem in which traditional methods often employ still-image techniques - labeling frames individually prior to a global decision. frame-based approaches, however, ignore significant cogent information brough ...201627693826
dismembered pyeloplasty in infants 6 months old or younger with and without external trans-anastomotic nephrostent: a prospective randomized study.to compare the outcome of dismembered pyeloplasty in infants with and without external nephro-ureteric stent (enus) for treatment of congenital ureteropelvic junction obstruction.201727693478
a randomized study of intraoperative autologous retropubic urethral sling on urinary control after robotic assisted radical prostatectomy.we evaluated whether placement of a retropubic urethral sling fashioned from autologous vas deferens during robotic assisted radical prostatectomy would improve recovery of continence.201727693447
dental esthetics and oral health-related quality of life in young adults.dental esthetics affects how people are perceived by society and how they perceive themselves, and this may also affect their oral health-related quality of life (ohrqol). the aim of this study was to compare the impacts of self-perceived and normatively assessed dental esthetics on the ohrqol of a young adult population.201627692420
a comparative study of patient characteristics, opinions, and outcomes, for patients who leave the emergency department before medical assessment.the emergency department (ed) left-without-being-seen (lwbs) rate is a performance indicator, although there is limited knowledge about why people leave, or whether they seek alternate care. we studied characteristics of ed lwbs patients to determine factors associated with lwbs.201627692013
allopurinol protective effect of renal ischemia by downregulating tnf-α, il-1β, and il-6 response.allopurinol is a well-known antioxidant that protects tissue against ischemia and reperfusion injury, blocking purine catabolism, and possibly reducing tnf-α and other cytokines. it also plays a significant role in reducing the inflammatory processes by inhibiting chemotaxis and other inflammatory mediators. the objective of this study was to define the role of allopurinol regarding kidney ischemic injury particularly as to its effect on inflammatory molecules such as tnf-α, il-1β, and il-6 resp ...201727690698
relationship of a1 segment hypoplasia to anterior communicating artery aneurysm morphology and risk factors for aneurysm formation.objective hypoplasia of the a1 segment of the anterior cerebral artery is frequently observed in patients with anterior communicating artery (acoa) aneurysms. the effect of this anatomical variant on acoa aneurysm morphology is not well understood. methods digital subtraction angiography images were reviewed for 204 patients presenting to the authors' institution with either a ruptured or an unruptured acoa aneurysm. the ratio of the width of the larger a1 segment to the smaller a1 segment was c ...201727689465
reactive-diffusive-advective traveling waves in a family of degenerate nonlinear equations.this paper deals with the analysis of existence of traveling wave solutions (tws) for a diffusion-degenerate (at d(0) = 0) and advection-degenerate (at h'(0) = 0) reaction-diffusion-advection (rda) equation. diffusion is a strictly increasing function and the reaction term generalizes the kinetic part of the fisher-kpp equation. we consider different forms of the convection term h(u): (1)  h'(u) is constant k, (2)  h'(u) = ku with k > 0, and (3) it is a quite general form which guarantees the de ...201727689131
evaluation of microbial reduction in root canals instrumented with reciprocating and rotary systems.this in vitro study aimed to evaluate the efficacy of the disinfection of root canal systems carried out with reciproc(tm) and protaper universal(tm) systems using 1% sodium hypochlorite (naocl).201527688413
ultrasound and mri predictors of surgical bowel resection in pediatric crohn disease.imaging predictors for surgery in children with crohn disease are lacking.201727687769
rehabilitating mussel beds in coffee bay, south africa: towards fostering cooperative small-scale fisheries governance and enabling community upliftment.along the coast of south africa, marine resources play a significant role in supporting livelihoods and contributing to food security in impoverished rural communities. post-apartheid fisheries laws and policies have begun to address traditional fishing rights and development needs, and new management arrangements are being implemented. one such initiative has been the mussel rehabilitation project in coffee bay, which piloted a resource rehabilitation technique at several over-exploited fishing ...201727686731
mobile extracorporeal membrane oxygenation teams: the north american versus the european experience.to evaluate differences in the inclusion of anesthesiologists in mobile extracorporeal membrane oxygenation (ecmo) teams between north american and european centers.201627686513
risk of infection after local field potential recording from externalized deep brain stimulation leads in parkinson's disease.adaptive deep brain stimulation (adbs) controlled by local field potentials (lfps) is considered a promising treatment for advanced parkinson's disease (pd). the clinical research investigating adbs functioning is performed using external deep brain stimulation (dbs) systems that require lfp recording through the temporary externalization of dbs leads. although research examining lfp was first undertaken more than 20 years ago, only a few studies concern lead externalization and lfp recording sa ...201727686508
the efficacy of tissue factor -603a/g and +5466a>g polimorphisms at the development of venous thromboembolism in cancer patients.venous thromboembolism (vte) is one of the most common complications in cancer patients. although factor v leiden (fvl) is the most common genetic defect causing thrombosis, the impact of gene abnormalities on thrombotic tendency in cancer patients remains poorly explored. tissue factor (tf) is a major physiologic initiator of blood coagulation. this is the first study regarding the association of tf gene -603a/g and +5466a>g polymorphisms with vte in malignancy. materials and me-thods: the stud ...201627685527
witnessing entanglement without entanglement witness operators.quantum mechanics predicts the existence of correlations between composite systems that, although puzzling to our physical intuition, enable technologies not accessible in a classical world. notwithstanding, there is still no efficient general method to theoretically quantify and experimentally detect entanglement of many qubits. here we propose to detect entanglement by measuring the statistical response of a quantum system to an arbitrary nonlocal parametric evolution. we witness entanglement ...201627681625
occupational injuries and diseases among commercial fishers in finland 1996-2015.commercial fishing is recognised as one of the most hazardous professions worldwide. in finland, commercial fishing has some special characteristics, including fishing on ice during frozen waters, and pluriactivity of the fisher family to gain additional income. the goal of this study was to describe injury characteristics among commercial fishers in finland during the years 1996-2015. with this information, we wish to promote creation of effective safety campaigns and interventions.201627681217
the backtracking search optimization algorithm for frequency band and time segment selection in motor imagery-based brain-computer interfaces.common spatial pattern (csp) is a powerful algorithm for extracting discriminative brain patterns in motor imagery-based brain-computer interfaces (bcis). however, its performance depends largely on the subject-specific frequency band and time segment. accurate selection of most responsive frequency band and time segment remains a crucial problem. a novel evolutionary algorithm, the backtracking search optimization algorithm is used to find the optimal frequency band and the optimal combination ...201627681162
fisher syndrome with delayed facial weakness and taste impairment: a case report.a 55-year-old man was admitted to our hospital because of acute onset of diplopia and gait disturbance. on admission, ophthalmoplegia, ataxia and areflexia were observed. he was diagnosed with fisher syndrome and given intravenous immunoglobulin therapy from day 6 to day 10 after disease onset. after treatment, ophthalmoplegia and ataxia began to improve. however, he developed taste impairment on day 13 and right hemifacial weakness on day 16 after onset. a blink reflex test revealed right facia ...201627680226
an overlap case of fisher syndrome and pharyngeal-cervical-brachial variant of guillain-barré syndrome associated with urinary retention and constipation.we report a 28-year-old woman with the overlap of fisher syndrome and pharyngeal-cervical-brachial variant of guillain-barré syndrome associated with urinary retention and constipation. she showed total ophthalmoplegia, dysphagia, dysarthria, upper extremity weakness, cerebellar ataxia, slightly diminished superficial sensations in her hands and feet, urinary retention and constipation 14 days after preceding infection. laboratory data showed elevations of antiganglioside antibodies to gt1b, gd1 ...201627680222
[comparison of ultrasound guided femoral and sciatic nerve block versus epidural anaesthesia for orthopaedic surgery in dogs].comparison of ultrasound-guided femoral and sciatic nerve block versus epidural anaesthesia with bupivacaine and morphine for orthopaedic surgery of the pelvic limb in dogs with respect to analgesic effectiveness, clinical utility and side effects.201727677086
poster 373-a immunoglobulin treatment of miller fisher variant of acute demyelinating inflammatory polyneuropathy with underlying chronic inflammatory demyelinating polyneuropathy: a case report. 201627673265
comprehensive analysis of genetic variations in strictly-defined leber congenital amaurosis with whole-exome sequencing in chinese.to make a comprehensive analysis of the potential pathogenic genes related with leber congenital amaurosis (lca) in chinese.201627672588
general anesthesia versus local anesthesia in stereotactic biopsies of brain lesions: a prospective randomized study.stereotactic biopsy of brain lesions with unknown entities is a common neurosurgical procedure to obtain tumor tissue. pathologists can then provide an exact diagnosis on which further therapy, such as resection, radiotherapy, or chemotherapy, can be based. these procedures can be performed under local or general anesthesia. in this prospective study, we aim to show whether stress levels are higher for patients who undergo stereotactic biopsy under local or general anesthesia.201727671885
comparison of prone vs. supine unenhanced ct imaging in patients with clinically suspected ureterolithiasis.to retrospectively evaluate whether prone ct scanning is superior to supine scanning for correct localization of distal urinary calculi in patients with acute flank pain.201727670877
traumatic injury risk and agricultural transitions: a view from the american southeast and beyond.bioarchaeological research has documented a general decline in health with the transition from foraging to farming, primarily with respect to changing patterns of morbidity. less is known about changes in injury risk, an aspect of health more obviously tied to particular landscapes and behaviors associated with different subsistence regimes. the purpose of this research is to evaluate several hypotheses emerging from the ideal free distribution model (fretwell & lucas, ) that predict injury risk ...201727670729
assessment of receiver signal strength sensing for location estimation based on fisher information.currently there is almost ubiquitous availability of wireless signaling for data communications within commercial building complexes resulting in receiver signal strength (rss) observables that are typically sufficient for generating viable location estimates of mobile wireless devices. however, while rss observables are generally plentiful, achieving an accurate estimation of location is difficult due to several factors affecting the electromagnetic coupling between the mobile antenna and the b ...201627669262
report of data on children with non-typhi salmonella gastroenteritis in a three-year period.the purpose of this study was to evaluate the clinical and laboratory data of children with acute gastroenteritis caused by non-typhoid salmonella spp. infections. clinical (demographic data, symptoms and findings) and laboratory data (stool microscopy, rapid antigen tests, culture, multiplex polymerase chain reaction and blood test results) of children with acute gastroenteritis caused by non-typhoid salmonella spp. between january 2010 and october 2012 were evaluated. differences between the g ...201627668899
taxonomy of malagasy nesomyrmex brevicornis species-group using conventional morphology-based approach.here we describe the diversity of the malagasy nesomyrmex brevicornis-group as the final installment of series describing the complete malagasy nesomyrmex fauna. in the current paper introduce the nesomyrmex brevicornis-group, a newly outlined species group. we split this group from one of the four former groups, nesomyrmex madecassus-group (sensu csősz and fisher 2015). the relatively small number of individuals available within the nesomyrmex brevicornis-group relative to the large number of o ...201627667950
implant stability quotients of osteotome bone expansion and conventional drilling technique for 4.1 mm diameter implant at posterior mandible.clinical conclusions in studying the stability and osseointegration of mandibular implants positioned using the bone expansion techniques are conflicting and limited.201727665748
the impact of sleep loss on the facilitation of seizures: a prospective case-crossover study.the relationship between sleep and seizures is intricate. the aim of this study was to assess whether sleep loss is an independent seizure precipitant in a clinical setting.201627665308
the impact of cyp4f2, abcb1, and ggcx polymorphisms on bleeding episodes associated with acenocoumarol in russian patients with atrial fibrillation.oral anticoagulants are commonly used to treat patients with thromboembolic pathology. genetic variations could influence personal response to anticoagulant drugs. acenocoumarol (ac) is a vitamin k antagonist used in anticoagulant therapy and as a prophylaxis measure in europe. in this study, we assessed the effect of cyp4f2 rs2108622, abcb1, and ggcx polymorphisms on the safety profile and regime dosing of ac in patients with nonvalvular atrial fibrillation.201627662649
bioimpedance to screen for abdominal fat in patients with breast cancer treatment-related lymphedema.one of the dreaded complications after the treatment of breast cancer is lymphedema. therapies used in the treatment of breast cancer such as surgery, radiotherapy, hormone therapy and chemotherapy may be adversely affected by obesity.201627662273
pelvic organ prolapse stage and the relationship to genital hiatus and perineal body measurements.this study aimed to describe the relationship between genital hiatus (gh) and perineal body (pb) measurements with increasing pelvic organ prolapse (pop) stage in a large cohort of women referred to urogynecology clinic for pelvic floor disorders.201727661212
distribution of lung blood on modified bilateral glenn shunt evaluated by tc-99m-maa lung perfusion scintigraphy: a retrospective study.the aim of the present study was to determine the distribution of lung blood in a modified bilateral glenn procedure designed in our institute with lung perfusion scintigraphy. sixteen consecutive patients who underwent modified bilateral glenn operation from 2011 to 2014 were enrolled in the study. the control group consisted of 7 patients who underwent bidirectional glenn shunt. radionuclide lung perfusion scintigraphy was performed using tc-99m-macro aggregated albumin (maa) in all patients. ...201627661042
a clinical study on single-visit root canal retreatments on consecutive 173 patients: frequency of periapical complications and clinical success rate.this study assessed the outcome measures of single-visit root canal retreatments and frequency of periapical complications considering preoperative, intraoperative and postoperative factors.201727660159
heavy metal concentration in periwinkle - tympanotomus fuscatus in iko river estuary, nigeria.heavy metals are intrinsic, natural constituents of our environment and are generally present in small amounts in natural aquatic environments. humans may be contaminated by organic and inorganic pollutants associated with aquatic systems by consumption of contaminated aquatic foods from the environment. relevant patents relating to heavy metal concentration in aquatic molluscs were reviewed. gastropods; a promising bio-indicator and bio-monitoring subject, abound in brackish ecosystems in the n ...201627659131
the impact of measurement of respiratory quotient by indirect calorimetry on the achievement of nitrogen balance in patients with severe traumatic brain injury.this study evaluated the impact of ic on the optimization of nutritional support and the achievement of +nb in patients with tbi.201627658944
clinical autoantibody detection by microarray.amidot is a microdot array-based immunoassay that allows simultaneous detection of multiple autoantibodies on a single patient. we evaluated the amidot "systemic autoimmune disease" (sad) panel, which detects antibodies to 17 different antigens.201727658157
the impact of chemotherapy on complications associated with mastectomy and immediate autologous tissue reconstruction.we performed this study to evaluate the impact of chemotherapy on the outcomes associated with immediate autologous tissue reconstruction (iatr) in the treatment of breast cancer. patients were divided into two groups: group 1 received chemotherapy before surgery and group 2 did not receive chemotherapy. records were reviewed to identify demographics, comorbidities, histology, and wound healing complications. groups were compared using kruskal-wallis and fisher exact tests as appropriate. a tota ...201627657587
improved efficiency and reliability of ngs amplicon sequencing data analysis for genetic diagnostic procedures using agsa software.screening for brca mutations in women with familial risk of breast or ovarian cancer is an ideal situation for high-throughput sequencing, providing large amounts of low cost data. however, 454, roche, and ion torrent, thermo fisher, technologies produce homopolymer-associated indel errors, complicating their use in routine diagnostics. we developed software, named agsa, which helps to detect false positive mutations in homopolymeric sequences. seventy-two familial breast cancer cases were analy ...201727656653
outcome analysis of locking plate fixation in proximal humerus fracture.proximal humerus fractures account for approximately 5% of all fractures. stable minimally displaced fractures can be treated nonoperatively but the management of displaced fractures remain controversial with various modalities of treatment available. locking plates provide stable fixation and enable early postoperative mobilization specially in osteoporotic proximal humerus fracture.201627656515
myd88 and functionally related genes are associated with multiple infections in a model population of kenyan village dogs.the purpose of this study was to seek associations between immunity-related molecular markers and endemic infections in a model population of african village dogs from northern kenya with no veterinary care and no selective breeding. a population of village dogs from northern kenya composed of three sub-populations from three different areas (84, 50 and 55 dogs) was studied. canine distemper virus (cdv), hepatozoon canis, microfilariae (acantocheilonema dracunculoides, acantocheilonema reconditu ...201627655108
clinical classification of 103 japanese patients with guillain-barré syndrome.guillain-barré syndrome (gbs) is the commonest cause of flaccid paralysis worldwide. miller fisher syndrome (mfs) is a variant of gbs characterized by ophthalmoplegia and ataxia. together gbs and mfs form a continuum of discrete and overlapping subtypes, the frequency of which remains unknown. we retrospectively analysed the clinical features (antecedent symptoms, pattern of neurological weakness or ataxia, presence of hypersomnolence) of 103 patients at a single hospital in japan. patients were ...201627653863
psychological and neuropsychological assessment of regular hoasca users.hoasca (also called ayahuasca) is a n,n-dimethyltryptamine (dmt) - containing psychedelic brew originally used for magico-religious purposes by amerindian populations of the amazon basin. recently, brazilian syncretic churches have helped spread the ritual use of hoasca to western societies. the aim of this study was to evaluate substance use, and neuropsychological and psychological functioning of regular hoasca users within a religious setting.201627653781
is interleukin 10 (il10) expression in breast cancer a marker of poor prognosis?interleukin 10 (il10) is a poor prognostic marker in several cancers. its role in breast cancer is not well elucidated. the present study is designed to see the expression of il10 in breast cancer tissue and to evaluate its correlation with the established markers of prognosis. sixty female patients who underwent surgery for breast cancer were enrolled for the study. immediately after surgery, 2-5 g of tumour tissue and similar volume of peritumoural normal breast tissue were collected for il10 ...201627651693
colposcopic study of lower genital tract infections in hiv-positive women on antiretroviral therapy.to study the colposcopic findings and prevalence of lower genital tract infections in hiv-positive women on anti-retroviral therapy. to find correlation between colposcopic finding, m rna hpv and cytology of lower genital tract infections in hiv-positive women on anti-retroviral therapy.201627651648
an innovative, no-cost, evidence-based smartphone platform for resident evaluation.timely performance evaluation and feedback are critical to resident development. however, formulating and delivering this information disrupts physician workflow, leading to low participation. this study was designed to determine if a locally developed smartphone platform would integrate regular evaluation into daily processes and thus increase faculty participation in timely resident evaluation.201727651056
[treatment of acute appendicitis: retrospective analysis].acute appendicitis is the most common cause of intra-abdominal emergency surgery worldwide. the approach to its treatment keeps changing. the number of acute appendectomies has been decreasing. many patients are treated conservatively with success. our study compares conservative and surgical treatment of acute appendicitis, including its complications in our department.201727650563
critical behavior of the quasi-two-dimensional semiconducting ferromagnet crsite3.the semiconducting ferromagnet crsite3 is a promising candidate for two-dimensional magnet simply by exfoliating down to single layers. to understand the magnetic behavior in thin-film samples and the possible applications, it is necessary to establish the nature of the magnetism in the bulk. in this work, the critical behavior at the paramagnetic to ferromagnetic phase transition in single-crystalline crsite3 is investigated by bulk magnetization measurements. we have obtained the critical expo ...201627649846
vegan-vegetarian low-protein supplemented diets in pregnant ckd patients: fifteen years of experience.pregnancy in women with advanced ckd becoming increasingly common. however, experience with low-protein diets in ckd patients in pregnancy is still limited. aim of this study is to review the results obtained over the last 15 years with moderately restricted low-protein diets in pregnant ckd women (combining: ckd stages 3-5, proteinuria: nephrotic at any time, or > =1 g/24 at start or referral; nephrotic in previous pregnancy). ckd patients on unrestricted diets were employed for comparison.201627649693
parathyroid ultrasonography and bone metabolic profile of patients on dialysis with hyperparathyroidism.to evaluate the parathyroid ultrasonography and define parameters that can predict poor response to treatment in patients with secondary hyperparathyroidism due to renal failure.201627648407
comparison of effectiveness and cost of patent ductus arteriosus device occlusion versus surgical ligation of patent ductus arteriosus.comparison of effectiveness and cost of transcatheter occlusion of patent ductus arteriosus (pda) with surgical ligation of pda.201727648051
machine learning to predict rapid progression of carotid atherosclerosis in patients with impaired glucose tolerance.prediabetes is a major epidemic and is associated with adverse cardio-cerebrovascular outcomes. early identification of patients who will develop rapid progression of atherosclerosis could be beneficial for improved risk stratification. in this paper, we investigate important factors impacting the prediction, using several machine learning methods, of rapid progression of carotid intima-media thickness in impaired glucose tolerance (igt) participants.201627642290
prognostic factors for facial nerve palsy in a pediatric population: a retrospective study and review.to identify and analyze factors influencing the outcome of facial nerve palsy (fnp) in a pediatric population.201727641905
an immunoassay to rapidly measure acetaminophen protein adducts accurately identifies patients with acute liver injury or failure.a rapid and reliable point-of-care assay to detect acetaminophen protein adducts in the serum of patients with acute liver injury could improve diagnosis and management. acetastat is a competitive immunoassay used to measure acetaminophen protein adducts formed by toxic metabolites in serum samples from patients. we compared the accuracy of acetastat vs high-pressure liquid chromatography with electrochemical detection (hplc-ec; a sensitive and specific quantitative analytic assay) to detect ace ...201727641661
catastrophic antiphospholipid syndrome (caps): descriptive analysis of 500 patients from the international caps registry.to analyze the clinical and immunologic manifestations of patients with catastrophic antiphospholipid syndrome (caps) from the "caps registry".201627639837
what are parents willing to discuss with their pediatrician about firearm safety? a parental survey.to determine if parents are receptive to discussing firearm safety with their pediatrician.201627639529
emergency non-occlusive high capacity bypass surgery for ruptured giant internal carotid artery aneurysms.managing ruptured giant internal carotid artery (ica) aneurysms in an emergency situation is very challenging. by reporting two cases, we discuss the role of the excimer laser-assisted non-occlusive anastomosis (elana) technique as an armamentarium for cerebrovascular surgeons dealing with giant ica aneurysms presenting with subarachnoid hemorrhage (sah).201627637632
results of clipping surgery for aneurysmal subarachnoid hemorrhage in elderly patients aged 90 or older.the number of elderly patients with aneurysmal subarachnoid hemorrhage (sah) is increasing. although advanced age is one of the recognized risk factors for poor outcome, conservative treatment for aneurysmal subarachnoid hemorrhage cannot provide satisfactory outcome in elderly patients. the aim of this study is to assess the outcome in patients aged 90 or older, for whom ruptured aneurysms were treated by clipping.201627637623
reproducibility, interchangeability of measures, time to measure stabilization, and reference values of two tissue oximeters in healthy volunteers.this study aimed to compare two tissue oximeters, the invos 5100c and the equanox 7600, in terms of their reproducibility and the interchangeability of their measures. in a randomized order, three measurements were taken at six different sites on both sides of the body in 53 healthy volunteers. intraclass correlation coefficients (icc) and within-subject standard deviation (sw) were calculated for each device. the iccs were compared using fisher r-to-z transformation and the sw were compared usi ...201627637007
walking out of the curve: thoracolumbar kyphosis in achondroplasia.thoracolumbar kyphosis (tlk) is common in infants with achondroplasia. our goals were to examine the natural history of tlk and identify factors associated with persistent tlk.201627636912
outcomes of sacral neuromodulation in patients with prior surgical treatment of stress urinary incontinence and pelvic organ prolapse.the aim of this study was to evaluate the efficacy of sacral neuromodulation in patients with prior stress urinary incontinence (sui) or pelvic organ prolapse (pop) surgery.201627636222
use of susceptibility-weighted imaging (swi) in the detection of brain hemorrhagic metastases from breast cancer and melanoma.susceptibility-weighted imaging (swi) has significantly increased our sensitivity in detecting hemorrhagic brain lesions. we sought to explore the prevalence of intratumoral hemorrhage as detected by swi in brain metastases from melanoma and breast cancer.201727636126
the necessity of using heparin in the ultratag rbc kit when tagging blood for a nuclear medicine study.the purpose of this research was to evaluate the need to use heparin when preparing an ultratag red blood cell (rbc) kit for a nuclear medicine study.201627634983
application of item response theory to modeling of expanded disability status scale in multiple sclerosis.in this study, we report the development of the first item response theory (irt) model within a pharmacometrics framework to characterize the disease progression in multiple sclerosis (ms), as measured by expanded disability status score (edss). data were collected quarterly from a 96-week phase iii clinical study by a blinder rater, involving 104,206 item-level observations from 1319 patients with relapsing-remitting ms (rrms), treated with placebo or cladribine. observed scores for each edss i ...201727634384
incidence of wound complications in cesarean deliveries following closure with absorbable subcuticular staples versus conventional skin closure techniques.to determine if there is a significant difference in composite wound complications among traditional closure techniques versus absorbable subcuticular staple closure.201627632411
rehabilitation of the atrophic posterior maxilla using splinted short implants or sinus augmentation with standard-length implants: a retrospective cohort study.to retrospectively compare short implants (6 to 8 mm) (short group) to standard-length implants (≥ 11 mm) inserted in combination with a lateral sinus elevation procedure (sinus group), supporting partial fixed prostheses in the atrophic posterior maxilla.201727632276
evaluation and comparison of multiple test methods, including real-time pcr, for legionella detection in clinical specimens.legionella is a gram-negative bacterium that can cause pontiac fever, a mild upper respiratory infection and legionnaire's disease, a more severe illness. we aimed to compare the performance of urine antigen, culture, and polymerase chain reaction (pcr) test methods and to determine if sputum is an acceptable alternative to the use of more invasive bronchoalveolar lavage (bal). data for this study included specimens tested for legionella at public health ontario laboratories from 1st january, 20 ...201627630979
institutional cost of unplanned 30-day readmission following open and endovascular surgery.vascular surgical patients have a high rate of readmission, and the cost of readmission for these patients has not been described. herein, we characterize and compare institutional index hospitalization and 30-day readmission cost following open and endovascular vascular procedures.201627630266
the formation of blood vessel after the administration of the plasmid encoding ang-1 gene in fischer rats.chronic limb ischemia is a serious clinical problem. patients who do not qualify for standard treatment may benefit from novel gene therapies.201727629833
three-dimensional computer-assisted modeling of talus morphology in chinese patients.to provide more accurate reference data for the assessment and treatment of talar injuries by constructing 3-d computer-assisted models of the talus and comparing them with reference data obtained from measurements on cadaver specimens.201627627723
results after implementation of a protocol on the incidence of urinary tract infection in an intensive care unit.to compare the results of urinary tract infection incidence, by means of the rate of indwelling urethral catheter use, and to identify microorganisms in urine cultures and surveillance cultures before and after the implementation of a clinical protocol for intensive care unit patients .201627627125
periapical microsurgery: the effects of locally injected dexamethasone on pain, swelling, bruising, and wound healing.the purpose of this prospective, double-blind, randomized clinical trial was to evaluate the postoperative healing of endodontic periapical microsurgery after local administration of dexamethasone.201627625146
higher cerebrospinal fluid ph may contribute to the development of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.recent investigations have shown that many factors may cause delayed cerebral ischemia (dci) after aneurysmal subarachnoid hemorrhage (sah). to find new potential contributors to dci, this retrospective study compared gas data in the cerebrospinal fluid (csf) between patients with and without dci. the subjects were 61 consecutive patients with sah classified as fisher group iii on admission computed tomography scans, whose aneurysms were obliterated by clipping or coiling within 24 h post-sah. t ...201727623837
immunocap® isac and microtest for multiplex allergen testing in people with difficult to manage allergic disease: a systematic review and cost analysis.allergy is a form of immune-mediated exaggerated sensitivity (hypersensitivity) to a substance that is either inhaled, swallowed, injected or comes into contact with the skin. foreign substances that provoke allergies are called allergens. it has been claimed that multiplex allergen testing may help in diagnosing the cause of symptoms in patients with an unclear cause of allergy or who are allergic to more than one substance.201627623692
magnetic field sensing subject to correlated noise with a ring spin chain.in this paper, we focus on the magnetic field sensing subject to a correlated noise. we use a ring spin chain with only the nearest neighbor interactions as our probe to estimate both the intensity b and the direction θ of the magnetic field when the probe reaches its steady state. we numerically calculate the quantum fisher information (qfi) to characterize the estimation precision. on the one hand, for estimating b, we find that the coupling between spins in the probe plays an important role i ...201627623048
effects of a 28-day dietary co-exposure to melamine and cyanuric acid on the levels of serum micrornas in male and female fisher 344 rats.we showed previously that a 28-day combined dietary exposure to melamine and cyanuric acid (mel&cya) induced kidney lesions in nctr fisher 344 (f344) rats. histopathological changes were significant in females dosed with ≥240 ppm mel&cya and in males dosed with ≥180 ppm mel&cya; however, the nephrotoxicity biomarkers blood urea nitrogen (bun) and serum creatinine (scr) were increased only by ≥240 ppm mel&cya. the serum mirnome has been reported to reflect toxicity of several organs, including th ...201627621052
development and validation of a high-fidelity phonomicrosurgical trainer.to validate the use of a high-fidelity phonomicrosurgical trainer.201727620827
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