Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| working and reference memory of pigs (sus scrofa domesticus) in a holeboard spatial discrimination task: the influence of environmental enrichment. | interest in cognitive research in pigs is increasing, but little is known about the impact of environmental conditions on pigs' cognitive capabilities. the present study investigated the effect of environmental enrichment on cognitive performance of pigs in a holeboard spatial task, in which they had to discriminate four baited buckets out of 16. pigs (n = 32) were either housed in stimulus-poor, barren pens, or in larger pens enriched with rooting substrates. pigs were subjected to 30 holeboard ... | 2013 | 23740471 |
| digestive physiology of the pig symposium: intestinal bile acid sensing is linked to key endocrine and metabolic signaling pathways. | bile acids have historically been considered to mainly function in cholesterol homeostasis and facilitate fat digestion in the gastrointestinal tract. recent discoveries show that bile acids also function as signaling molecules that exert diverse endocrine and metabolic actions by activating g protein-coupled bile acid receptor 1 (gpbar1/g-protein-coupled bile acid receptor 1 or tgr5), a membrane g protein-coupled receptor, and farnesoid x receptor (fxr), a member of the nuclear hormone receptor ... | 2013 | 23729782 |
| insulin affects sperm capacity in pig through nitric oxide. | insulin (ins) has recently been demonstrated to have the ability to induce the capacitation process in pig spermatozoa. in various mammalian species, capacitation has been linked to the nitric oxide (no) signalling; therefore, this study investigated no production in ins-treated pig spermatozoa by fluorescence-activated cell sorting. for the same samples, sperm capacitation was evaluated by chlortetracycline staining, protein tyrosine phosphorylation pattern and acrosomal status. a significant i ... | 2013 | 23728590 |
| deletion of virulence associated genes from attenuated african swine fever virus isolate our t88/3 decreases its ability to protect against challenge with virulent virus. | african swine fever virus (asfv) causes an acute haemorrhagic disease of domestic pigs against which there is no effective vaccine. the attenuated asfv strain our t88/3 has been shown previously to protect vaccinated pigs against challenge with some virulent strains including our t88/1. two genes, dp71l and dp96r were deleted from the our t88/3 genome to create recombinant virus our t88/3δdp2. deletion of these genes from virulent viruses has previously been shown to reduce asfv virulence in dom ... | 2013 | 23725691 |
| comparative genomics of salmonella enterica serovars derby and mbandaka, two prevalent serovars associated with different livestock species in the uk. | despite the frequent isolation of salmonella enterica sub. enterica serovars derby and mbandaka from livestock in the uk and usa little is known about the biological processes maintaining their prevalence. statistics for salmonella isolations from livestock production in the uk show that s. derby is most commonly associated with pigs and turkeys and s. mbandaka with cattle and chickens. here we compare the first sequenced genomes of s. derby and s. mbandaka as a basis for further analysis of the ... | 2013 | 23725633 |
| features of hepatitis e virus infection in humans and animals in japan. | in japan, hepatitis e had long been considered to be a rare liver disease which can be accidentally imported from endemic countries in asia and africa, where the sanitation conditions are suboptimal. however, since the identification of the first autochthonous hepatitis e case and hepatitis e viremic domestic pigs in japan in 2001, our understanding of hepatitis e virus (hev) infection in this country has been changing markedly. this has largely been due to the development of serological and gen ... | 2014 | 23721425 |
| molecular investigation of torque teno sus virus in geographically distinct porcine breeding herds of sichuan, china. | torque teno sus virus (ttsuv), infecting domestic swine and wild boar, is a non-enveloped virus with a circular, single-stranded dna genome. which has been classified into the genera iotatorquevirus (ttsuv1) and kappatorquevirus (ttsuv2) of the family anelloviridae. a molecular study was conducted to detect evidence of a phylogenic relationship between these two porcine ttsuv genogroups from the sera of 244 infected pigs located in 21 subordinate prefectures and/or cities of sichuan. | 2013 | 23705989 |
| experimental evaluation of pharmacokinetic profile and biological effect of a novel paclitaxel microcrystalline balloon coating in the iliofemoral territory of swine. | new paclitaxel coated balloons (pcb) developments have been proposed to maintain therapeutic levels of drug in the tissue while decreasing particle release. in this series of studies, we evaluated the pharmacokinetic profile and biological effects after paclitaxel delivery via novel microcrystalline pcb coating (mcpcb, pax®, balton) in porcine iliofemoral arteries. | 2014 | 23703720 |
| local hemodynamic disturbance accelerates early thrombosis of small-caliber expanded polytetrafluoroethylene grafts. | small-caliber expanded polytetrafluoroethylene (eptfe) grafts cannot be used widely in the clinical situation because of early thrombosis and occlusion. this unsolved and under-recognized problem warrants further investigation. | 2013 | 23703290 |
| classical swine fever. | classical swine fever is a serious and economically important transboundary disease threatening pig production globally. the infection may occur in backyard pigs, feral pig populations and domestic pigs. whereas there are proven control strategies for the latter pig population, control in backyard pigs with poor biosecurity settings or in wild boar populations of high density still poses a problem in some parts of the world. laboratory diagnostic methods, efficacious vaccines and contingency pla ... | 2013 | 23689894 |
| mild therapeutic hypothermia is superior to controlled normothermia for the maintenance of blood pressure and cerebral oxygenation, prevention of organ damage and suppression of oxidative stress after cardiac arrest in a porcine model. | mild therapeutic hypothermia (ht) has been implemented in the management of post cardiac arrest (ca) syndrome after the publication of clinical trials comparing ht with common practice (ie, usually hyperthermia). current evidence on the comparison between therapeutic ht and controlled normothermia (nt) in ca survivors, however, remains insufficient. | 2013 | 23688243 |
| reintroductions and genetic introgression from domestic pigs have shaped the genetic population structure of northwest european wild boar. | population genetic studies focus on natural dispersal and isolation by landscape barriers as the main drivers of genetic population structure. however, anthropogenic factors such as reintroductions, translocations and wild x domestic hybridization may also have strong effects on genetic population structure. in this study we genotyped 351 single nucleotide polymorphism markers evenly spread across the genome in 645 wild boar (sus scrofa) from northwest europe to evaluate determinants of genetic ... | 2013 | 23688182 |
| disposition and excretion of 14c-ahtn (7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene) and 14c-hhcb (1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta-gamma-2-benzopyran) after intravenous administration to sprague-dawley rats and domestic pigs. | 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene (ahtn ) and 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-gamma-2-benzopyran (hhcb) are polycyclic musks widely used as fragrance ingredients in consumer products. because their metabolic fate following systemic exposure is not fully characterized, disposition and excretion of (14)c-ahtn- and (14)c-hhcb-derived radioactivity were studied in sprague-dawley rats and domestic pigs following a single intravenous dose. rats admini ... | 2013 | 23685777 |
| a novel non-vascular system to treat resistant hypertension. | to evaluate in a preclinical model the utility of a monopolar electrode catheter delivering radiofrequency (rf) energy placed into the renal pelvis in order to treat resistant hypertension (rh). | 2013 | 23685301 |
| effects of cognitive enrichment on behavioural and physiological reactions of pigs. | cognitive enrichment, a special form of environmental enrichment, addresses the cognitive abilities of animals in captivity. through cognitive interaction with the environment, the animals regain a certain control over their environment, and essential resources, such as food or water, act as a reward for successful coping. it is assumed that this process has important implications for animal welfare, especially in the intensive housing systems of farm animals. this study investigates the effects ... | 2013 | 23680428 |
| us-guided application of nd:yag laser in porcine pancreatic tissue: an ex vivo study and numerical simulation. | laser ablation (la) with a neodymium-doped yttrium aluminum garnet (nd:yag) laser is a minimally invasive approach able to achieve a high rate of complete tissue necrosis. in a previous study we described the feasibility of eus-guided nd:yag pancreas la performed in vivo in a porcine model. | 2013 | 23680175 |
| crushed rephased orthogonal slice selection (cross) for simultaneous acquisition of two orthogonal proton resonance frequency temperature maps. | to evaluate a novel imaging sequence termed crushed rephased orthogonal slice selection (cross) that uses the available time in long echo time (te) gradient echo (gre) imaging-as employed for proton resonance frequency (prf) shift thermometry-to simultaneously acquire two orthogonal magnetic resonance imaging (mri) temperature maps around the target region. | 2013 | 23677906 |
| structural and functional annotation of the porcine immunome. | the domestic pig is known as an excellent model for human immunology and the two species share many pathogens. susceptibility to infectious disease is one of the major constraints on swine performance, yet the structure and function of genes comprising the pig immunome are not well-characterized. the completion of the pig genome provides the opportunity to annotate the pig immunome, and compare and contrast pig and human immune systems. | 2013 | 23676093 |
| cloning changes the response to obesity of innate immune factors in blood, liver, and adipose tissues in domestic pigs. | the objective of this study was to evaluate the usefulness of cloned pigs as porcine obesity models reflecting obesity-associated changes in innate immune factor gene expression profiles. liver and adipose tissue expression of 43 innate immune genes as well as serum concentrations of six immune factors were analyzed in lean and diet-induced obese cloned domestic pigs and compared to normal domestic pigs (obese and lean). the number of genes affected by obesity was lower in cloned animals than in ... | 2013 | 23668862 |
| immunogenicity and safety of a natural rough mutant of brucella suis as a vaccine for swine. | the objective of the current study was to evaluate the safety, immunogenicity and clearance of the natural rough mutant of brucella suis strain 353-1 (353-1) as a vaccine in domestic swine. in three studies encompassing 105 animals, pigs were inoculated with 353-1 by conjunctival (5 × 10(7) cfu) or im (1-2 × 10(10) cfu) routes. clearance, tissue distribution, and pathology of the vaccine strain were determined by periodic blood culture, collection of tissues at periodic necropsy times after vacc ... | 2013 | 23659743 |
| administration of amiodarone during resuscitation is associated with higher tumor necrosis factor-α levels in the early postarrest period in the swine model of ischemic ventricular fibrillation. | to compare the early postarrest inflammatory cytokine response between animals administered amiodarone (amio) and lidocaine (lido) intra-arrest during resuscitation from ventricular fibrillation (vf). domestic swine (n=32) were placed under general anesthesia and instrumented before spontaneous vf was induced by balloon occlusion of the left anterior descending coronary artery. after 7 min of vf, standard acls resuscitation was performed and animals were randomized to either bolus amio (5 mg/kg, ... | 2013 | 23659671 |
| porcine e. coli: virulence-associated genes, resistance genes and adhesion and probiotic activity tested by a new screening method. | we established an automated screening method to characterize adhesion of escherichia coli to intestinal porcine epithelial cells (ipec-j2) and their probiotic activity against infection by enteropathogenic e. coli (epec). 104 intestinal e. coli isolates from domestic pigs were tested by pcr for the occurrence of virulence-associated genes, genes coding for resistances to antimicrobial agents and metals, and for phylogenetic origin by pcr. adhesion rates and probiotic activity were examined for c ... | 2013 | 23658605 |
| [effect of ulinastatin on improving inflammatory response and myocardial and lung tissue injury after cardiopulmonary resuscitation in pigs]. | to evaluate the effects of ulinastatin (uti) on improving inflammatory response and myocardial and lung tissue injury after cardiopulmonary resuscitation (cpr) in porcine model. | 2013 | 23648163 |
| serological and molecular investigation of the prevalence of aujeszky's disease in feral swine (sus scrofa) in the subregions of the pantanal wetland, brazil. | the feral swine (fs) originated from the domestic pig and is present throughout the brazilian wetland plain (the pantanal). aujeszky's disease (ad) was first serologically confirmed in the state of mato grosso do sul (ms) in 2001; however, there was no viral confirmation. the aim of this study was to investigate antibodies against-suhv-1 in the sera of feral swine in the studied areas, detect suhv-1 through pcr and classify the viral genome. among the 218 animals sampled, 186 were analyzed by el ... | 2013 | 23639473 |
| constitutive expression of cyp3a mrna in bama miniature pig tissues. | the pig, particularly the miniature pig (minipig), is becoming an important animal model due to its physiological and anatomical similarities to humans. bama minipigs (sus scrofa domestica), a chinese natural minipig breed, are a promising animal model. the pig is a useful model for drug metabolism and pharmacological studies due to the similar properties of cytochrome p450 (cyp)3a between pigs and humans. however, a detailed investigation regarding the abundance and expression of cyp3a in porci ... | 2013 | 23618816 |
| primary proteasome inhibition results in cardiac dysfunction. | the proteasome prevents the intracellular accumulation of proteins and its impairment can lead to structural and functional alterations, as noted for the coronary vasculature in a previous study. utilizing the same model, this study was designed to test the hypothesis that chronic proteasome inhibition (psi) also leads to structural and functional changes of the heart. | 2013 | 23616520 |
| angiotensin receptor blockade has protective effects on the poststenotic porcine kidney. | angiotensin-converting enzyme inhibitors/angiotensin ii receptor blockers (arbs) may induce an acute decrease of glomerular filtration rate (gfr) in the stenotic kidney in renal artery stenosis, but most patients tolerate these drugs well. we hypothesized that angiotensin-converting enzyme inhibitors/arbs stabilize stenotic kidney function during prolonged treatment by conferring protective effects. we tested this in control domestic pigs and pigs with renal artery stenosis untreated or treated ... | 2013 | 23615504 |
| protective effects of ranolazine and propranolol, alone or combined, on the structural and functional alterations of cardiomyocyte mitochondria in a pig model of ischemia/reperfusion. | preventing the consequences of ischemia/reperfusion (i/r)-induced lesions in the clinic requires the administration of pharmacological agents prior to restoring coronary vascularization. the aim of this study was to evaluate the effects of ranolazine and propranolol when administered either alone or combined prior to i/r induction in a pig model. thirty domestic pigs were randomly assigned to five groups of six animals including (i) sham animals; (ii) untreated animals with 45-min ischemia and 1 ... | 2014 | 23607936 |
| activation of indoleamine 2,3-dioxygenase by lps in a porcine model. | indoleamine 2,3-dioxygenase (ido) is a rate-limiting enzyme for the degradation of tryptophan (trp) along the kynurenine (kyn) pathway, and its increased activation is associated with immunologic disorders. because the specific role of ido activation is not yet completely clear, the aim of the present study was to establish a pig model of ido activation for further research. the activation of ido in pigs was induced experimentally by lps stimulation in vivo and ex vivo. ido activation was charac ... | 2014 | 23606516 |
| cytochrome b based genetic differentiation of indian wild pig (sus scrofa cristatus) and domestic pig (sus scrofa domestica) and its use in wildlife forensics. | the indian wild pig (sus scrofa cristatus) is a protected species and listed in the indian wildlife (protection) act, 1972. the wild pig is often hunted illegally and sold in market as meat warranting punishment under law. to avoid confusion in identification of these two subspecies during wildlife forensic examinations, we describe genetic differentiation of indian wild and domestic pigs using a molecular technique. analysis of sequence generated from the partial fragment (421bp) of mitochondri ... | 2012 | 23601732 |
| complete genome sequences of classical swine fever virus strains isolated from wild boars in south korea. | classical swine fever is a disease that is devastating the pig industry worldwide. here, we report the complete genome sequences of two classical swine virus strains (yc11wb and pc11wb), isolated from korean wild boars in 2011. both strains belong to subgenotype 2.1b. the complete genome sequences of pc11wb and yc11wb are more similar to that of strain zj0801 (isolated in china) than to that of the sw03 strain isolated from domestic pigs in south korea. | 2013 | 23599291 |
| hepatitis e: a puzzling double-faced disease. | viral hepatitis type e is highly endemic in many developing countries, where large water-borne epidemics caused by viral genotype 1 and - to a lesser degree - by genotype 2 cyclically occur, resulting in high morbidity and mortality, especially among pregnant women. in developed countries, the disease is usually diagnosed in travelers coming back from endemic countries, but an increasing number of sporadic locally acquired hepatitis cases caused by genotype 3 and 4 have recently been reported. t ... | 2013 | 23598800 |
| phylogenetic analyses of novel squamate adenovirus sequences in wild-caught anolis lizards. | adenovirus infection has emerged as a serious threat to the health of captive snakes and lizards (i.e., squamates), but we know relatively little about this virus' range of possible hosts, pathogenicity, modes of transmission, and sources from nature. we report the first case of adenovirus infection in the iguanidae, a diverse family of lizards that is widely-studied and popular in captivity. we report adenovirus infections from two closely-related species of anolis lizards (anoles) that were re ... | 2013 | 23593364 |
| a lumen sizing workhorse guidewire for peripheral vasculature: two functions in one device. | ideally, guidewires used during peripheral vasculature (pv) interventions could serve both as a therapy delivery platform and a diagnostic tool for real-time vessel sizing (2-in-1 function). | 2014 | 23592431 |
| soybean yield and heterodera glycines responses to liquid swine manure in nematode suppressive soil and conducive soil. | the soybean cyst nematode (scn), heterodera glycines, is a major factor limiting soybean yield. experiments were conducted in 2009 and 2010 to determine the effects of liquid swine manure and chemical fertilizer pk on soybean and corn yields, and on scn population in an scn-suppressive field (s-site) and an scn-conducive field (c-site) in minnesota. the experiment was a split-plot design with crop sequences as main plots and fertilizer treatments as subplots. the 2-yr crop sequences were sus-sus ... | 0 | 23589656 |
| focused ultrasound to expel calculi from the kidney: safety and efficacy of a clinical prototype device. | focused ultrasound has the potential to expel small stones or residual stone fragments from the kidney, or move obstructing stones to a nonobstructing location. we evaluated the efficacy and safety of ultrasonic propulsion in a live porcine model. | 2013 | 23583535 |
| antegrade side branch access in branched aortic arch endografts: a porcine feasibility study. | to describe the deployment technique for a single side branch arch endograft in a porcine model and prove the concept of transseptal or transapical antegrade access for catheterization and introduction of the mating stent-graft. | 2013 | 23581770 |
| feasibility of endoscopic transumbilical thoracic sympathectomy in a porcine model. | thoracoscopic sympathectomy is an effective treatment for palmar hyperhidrosis. current methods are associated with risks of chronic neuropathic pain and a visible chest scar. we developed a novel surgical technique for the performance of sympathectomy by embryonic natural orifice transumbilical endoscopic surgery with a flexible endoscope in a porcine model. | 2013 | 23579034 |
| experimental infection of european starlings (sturnus vulgaris) and house sparrows (passer domesticus) with pandemic 2009 h1n1 and swine h1n1 and h3n2 triple reassortant influenza viruses. | european starlings (sturnus vulgaris) and house sparrows (passer domesticus) are common peridomestic passerine birds that are often associated with domestic animal production facilities. this association provides a potential means for pathogen transmission between facilities. we inoculated european starlings and house sparrows with three non-avian influenza virus strains: two swine isolates (h1n1 and h3n2) and one human isolate representing the h1n1 pandemic strain that originated from swine. no ... | 2013 | 23568924 |
| highly porous hydroxyapatite with and without local harvested bone in sinus floor augmentation: a histometric study in pigs. | sinus floor augmentation with autologous bone is an accepted treatment option in dental implantology. in this study, an entirely synthetic, nano-structured, hydroxyapatite-based bone substitute material (sbsm, nanobone(®); artoss, rostock, germany) was supplemented with a mixture of locally harvested bone to enhance osteogenesis. | 2014 | 23566297 |
| multi frequency phase fluorimetry (mfpf) for oxygen partial pressure measurement: ex vivo validation by polarographic clark-type electrode. | measurement of partial pressure of oxygen (po2) at high temporal resolution remains a technological challenge. this study introduces a novel po2 sensing technology based on multi-frequency phase fluorimetry (mfpf). the aim was to validate mfpf against polarographic clark-type electrode (cte) po2 measurements. | 2013 | 23565259 |
| clean technique for prolonged nonsurvival cardiothoracic surgery in swine (sus scrofa). | laboratory animal regulations provide little guidance regarding duration of nonsurvival surgery requiring aseptic technique. we hypothesized that swine would experience no sepsis during nonsurvival cardiothoracic surgery accomplished by using clean technique and lasting 8 h or less. incision sites of 5 male farm pigs (sus scrofa) were shaved and then cleaned with alcohol and povidone-iodine. the surgeon wore sterile gloves, clean scrubs, and hair bonnet; assistants wore clean scrubs and nonsteri ... | 2013 | 23562035 |
| effects of mobilization regimens in donors on outcomes of hematopoietic cell transplantation in miniature swine. | toxicities and complications associated with hematopoietic cell transplantation currently limit this potentially curative therapy for malignant and nonmalignant blood disorders. miniature swine provide a clinically relevant model for studies to improve posttransplantation outcomes. miniature swine recipients of high-dose haploidentical hepatopoietic cell transplantation after reduced-intensity conditioning consisting of low-dose (100 cgy) total-body irradiation, partial t-cell depletion by using ... | 0 | 23561882 |
| prevalence of porcine hokovirus and its co-infection with porcine circovirus 2 in china. | here, we report the frequency of porcine hokovirus (phov) infection and its co-infection with porcine circovirus 2 (pcv2) in china. a total of 485 domestic pig samples were tested for both phov and pcv2, and ns1 gene sequences from 11 phov strains were used for phylogenetic analysis. the prevalence of phov and pcv2 was 51.3 % and 36.3 %, respectively, and co-infection occurred in 20.2 %. phovs from the chinese mainland showed a close relationship to those isolated in hong kong. co-infection with ... | 2013 | 23558802 |
| novel insights into the genetic diversity of balantidium and balantidium-like cyst-forming ciliates. | balantidiasis is considered a neglected zoonotic disease with pigs serving as reservoir hosts. however, balantidium coli has been recorded in many other mammalian species, including primates. here, we evaluated the genetic diversity of b. coli in non-human primates using two gene markers (ssrdna and its1-5.8sdna-its2). we analyzed 49 isolates of ciliates from fecal samples originating from 11 species of captive and wild primates, domestic pigs and wild boar. the phylogenetic trees were computed ... | 2013 | 23556024 |
| pandemic influenza a viruses escape from restriction by human mxa through adaptive mutations in the nucleoprotein. | the interferon-induced dynamin-like mxa gtpase restricts the replication of influenza a viruses. we identified adaptive mutations in the nucleoprotein (np) of pandemic strains a/brevig mission/1/1918 (1918) and a/hamburg/4/2009 (ph1n1) that confer mxa resistance. these resistance-associated amino acids in np differ between the two strains but form a similar discrete surface-exposed cluster in the body domain of np, indicating that mxa resistance evolved independently. the 1918 cluster was conser ... | 2013 | 23555271 |
| cranial nerve threshold for thermal injury induced by mri-guided high-intensity focused ultrasound (mrghifu): preliminary results on an optic nerve model. | future clinical applications of magnetic resonance imaging-guided high-intensity focused ultrasound (mrghifu) are moving toward the management of different intracranial pathologies. we sought to validate the production, safety, and efficacy of thermal injury to cranial nerves generated by mrghifu. in this study, five female domestic pigs underwent a standard bifrontal craniectomy under general anesthesia. treatment was then given using an mrghifu system to induce hyperthermic ablative sonication ... | 2013 | 23549530 |
| spectrophotometric retinal oximetry in pigs. | to assess the validity of spectrophotometric retinal oximetry by comparison to blood gas analysis and intravitreal measurements of partial pressure of oxygen (po(2)). | 2013 | 23532527 |
| successive and conditional discrimination learning in pigs. | we studied the ability of pigs to discriminate tone cues using successive and conditional discrimination tasks. pigs (n = 8) were trained in a successive discrimination go/no-go task (experiment 1) to associate a go-cue with a reward at the end of a runway and a no-go-cue with the absence of reward. latency to reach the goal-box was recorded for each cue-type. learning of a conditional discrimination task was compared between low-birthweight (lbw, n = 5) and normal-birthweight (nbw, n = 6) pigs ... | 2013 | 23525688 |
| hepatitis e virus seroprevalence of domestic pigs in germany determined by a novel in-house and two reference elisas. | autochthonous hepatitis e virus (hev) infections by zoonotic transmission of genotype 3 (gt3) have been reported increasingly from industrialized countries. in this paper the development and validation of an igg elisa for the detection of hev-specific antibodies in domestic pigs is described. comparison of the diagnostic value of escherichia coli-expressed hev-gt3 capsid protein (cp) derivatives revealed a carboxy-terminal derivative as most suitable. validation of the in-house assay using a com ... | 2013 | 23523888 |
| review: influenza virus in pigs. | influenza virus disease still remains one of the major threats to human health, involving a wide range of animal species and pigs play an important role in influenza ecology. pigs were labeled as "mixing vessels" since they are susceptible to infection with avian, human and swine influenza viruses and genetic reassortment between these viruses can occur. after the h1n1 influenza pandemic of 2009 with a swine origin virus, the most recent research in "influenzology" is directed at improving knowl ... | 2013 | 23523121 |
| classical swine fever in the pygmy hog. | the pygmy hog is a rare, small and highly endangered mammal belonging to the suidae family, and it is presently found only in the assam state of india. while investigating the cause of death of pygmy hogs housed at a conservation centre for captive breeding and research at basistha, assam, it was confirmed that they were susceptible to and died as a result of contracting classical swine fever (csf), caused by csf virus (csfv), which is a highly infectious endemic disease of domestic pigs in indi ... | 2012 | 23520745 |
| pig lumbar spine anatomy and imaging-guided lateral lumbar puncture: a new large animal model for intrathecal drug delivery. | intrathecal (it) administration is an important route of drug delivery, and its modelling in a large animal species is of critical value. although domestic swine is the preferred species for preclinical pharmacology, no minimally invasive method has been established to deliver agents into the it space. while a "blind" lumbar puncture (lp) can sample cerebrospinal fluid (csf), it is unreliable for drug delivery in pigs. using computed tomography (ct), we determined the underlying anatomical reaso ... | 2013 | 23518340 |
| phasic contractions in urinary bladder from juvenile versus adult pigs. | alterations in properties of the bladder with maturation are relevant physiologically and pathophysiologically. the aim of this study was to investigate alterations in bladder properties with maturation in juvenile vs. adult pig, focussing on differences between layers of the bladder wall (mucosa vs. detrusor) and the presence and functional contribution of interstitial cells (ics). | 2013 | 23516515 |
| too fresh is unattractive! the attraction of newly emerged nicrophorus vespilloides females to odour bouquets of large cadavers at various stages of decomposition. | the necrophagous burying beetle nicrophorus vespilloides reproduces on small carcasses that are buried underground to serve as food for their offspring. cadavers that are too large to bury have previously been postulated to be important food sources for newly emerged beetles; however, the attractiveness of distinct successive stages of decomposition were not further specified. therefore, we investigated the potential preference of newly emerged n. vespilloides females for odour bouquets of pigle ... | 2013 | 23516497 |
| fatal infection due to haemophilus parasuis in a young wild boar (sus scrofa). | haemophilus parasuis is a recognized pathogen in domestic pigs; the pathogen has been also isolated from healthy wild boar (sus scrofa). in the current report, a case of fatal h. parasuis infection in a wild boar piglet from central spain is described. the affected animal presented severe pneumonic lesions, inflammation in tarsal joints with presence of fibrinous deposits, and epidural hemorrhage in the atlanto-occipital joint. pure growth of h. parasuis was obtained from lungs and tarsal joints ... | 2013 | 23512924 |
| effects of pretreatment hypothermia during resuscitated porcine hemorrhagic shock. | accidental hypothermia increases mortality and morbidity after hemorrhage, but controversial data are available on the effects of therapeutic hypothermia. therefore, we tested the hypothesis whether moderate pretreatment hypothermia would beneficially influence organ dysfunction during long-term, porcine hemorrhage and resuscitation. | 2013 | 23507715 |
| meat from wild boar (sus scrofa l.): a review. | wild boar is a species that is utilised for food and sport hunting throughout the world. recent increases in natural populations and the potential of farming wild boars have stimulated interest in this species as a meat producer. compared to domestic pigs, wild boars present a higher degree of carcass fatness and larger loin areas, more slow-twitch oxidative (i) and fast-twitch oxidative glycolytic (iia) and less fast-twitch glycolytic (iib) muscle fibres, and darker, less tender and leaner meat ... | 2013 | 23501250 |
| are juvenile domestic pigs (sus scrofa domestica) sensitive to the attentive states of humans?--the impact of impulsivity on choice behaviour. | previous studies have shown that apes, dogs and horses seem to be able to attribute attentive states to humans. subjects had to choose between two persons: one who was able to see the animal and one who was not. using a similar paradigm, we tested a species that does not rely strongly on visual cues, the domestic pig (sus scrofa domestica). subjects could choose between two unfamiliar persons, with only one showing attention, in three different conditions (body, head away, body turned - head fro ... | 2013 | 23500190 |
| the phylogenetic status of typical chinese native pigs: analyzed by asian and european pig mitochondrial genome sequences. | china is one of the most diverse countries, which have developed 88 indigenous pig breeds. several studies showed that pigs were independently domesticated in multiple regions of the world. the purpose of this study was to investigate the origin and evolution of chinese pigs using complete mitochondrial genomic sequences (mtdna) from asian and european domestic pigs and wild boars. thirty primer pairs were designed to determine the mtdna sequences of xiang pig, large white, lantang, jinhua and p ... | 2013 | 23497624 |
| the spatial ecology of free-ranging domestic pigs (sus scrofa) in western kenya. | in many parts of the developing world, pigs are kept under low-input systems where they roam freely to scavenge food. these systems allow poor farmers the opportunity to enter into livestock keeping without large capital investments. this, combined with a growing demand for pork, especially in urban areas, has led to an increase in the number of small-holder farmers keeping free range pigs as a commercial enterprise. despite the benefits which pig production can bring to a household, keeping pig ... | 2013 | 23497587 |
| make the most of your samples: bayes factor estimators for high-dimensional models of sequence evolution. | accurate model comparison requires extensive computation times, especially for parameter-rich models of sequence evolution. in the bayesian framework, model selection is typically performed through the evaluation of a bayes factor, the ratio of two marginal likelihoods (one for each model). recently introduced techniques to estimate (log) marginal likelihoods, such as path sampling and stepping-stone sampling, offer increased accuracy over the traditional harmonic mean estimator at an increased ... | 2013 | 23497171 |
| detection of rickettsia parkeri from within piura, peru, and the first reported presence of candidatus rickettsia andeanae in the tick rhipicephalus sanguineus. | domestic farm animals (n=145) were sampled for the presence of ectoparasites in northwestern peru during march, 2008. ninety domestic animals (62%) were positive for the presence of an ectoparasite(s) and produced a total collection of the following: 728 ticks [amblyomma maculatum, anocentor nitens, rhipicephalus (boophilus) microplus, rhipicephalus sanguineus, and otobius megnini], 12 lice (haematopinus suis), and 3 fleas (ctenocephalides felis). a rickettsia genus-specific qpcr assay was perfo ... | 2013 | 23488453 |
| laparoscopic partial nephrectomy using a flexible co2 laser fiber. | laparoscopic partial nephrectomy (lpn) is a challenging surgery that requires precise tissue cutting and meticulous hemostasis under warm ischemia conditions. in this study, we tested the feasibility of performing lpn using co2 laser energy transmitted through a specialized flexible mirror optical fiber. | 2012 | 23484569 |
| [study on hepatocyte apoptosis of domestic pigs experimentally infected with taenia asiatica and taenia saginata]. | to investigate apoptosis in liver tissue of the domestic pigs infected with eggs of taenia asiatica and taenia saginata. | 2012 | 23484276 |
| range of blood lactate values in farm pigs prior to experimental surgery. | in biomedical research the pig is widely used as an animal model for experimental surgery. feasible monitoring tools during anaesthesia are pivotal for successful and reliable research outcome. blood lactate values are a monitoring tool and prognostic indicator during surgery both in humans and animals. lactate levels in pigs might be influenced by various parameters including stressful handling, breed and weight differences. to determine blood lactate levels present prior to experimental surger ... | 2013 | 23479774 |
| molecular detection and genomic characterization of torque teno sus virus 1 and 2 from domestic pigs in central china. | in the present study, torque teno sus viruses (ttsuvs) were detected in tissue and blood samples obtained from domestic pigs in central china, and complete genomes of ttsuvs were characterized. a total of three tissue samples (3/20, 15 %) from post-weaning multisystemic wasting syndrome-affected pigs and 30 blood samples (30/40, 75 %) from healthy pigs were positive for torque teno sus virus 1 (ttsuv1) and/or 2 (ttsuv2). two ttsuv strains (ttv1hn54 and ttv2hn93) comprising 2,794 and 2,875 nucleo ... | 2013 | 23468229 |
| determination of coenzyme q10 tissue status via high-performance liquid chromatography with electrochemical detection in swine tissues (sus scrofa domestica). | swine tissues were used as surrogates for human tissues with coenzyme q10 (coq10) as the primary endogenous quinoid to establish a reliable method for the analysis of total coq10 concentration and redox status using the reduced and oxidized forms of coq9 as internal standards. specimens of frozen swine tissues were disrupted by bead milling using 2-propanol as the homogenization medium supplemented with the internal standards. after hexane extraction, coq10 was analyzed via high-performance liqu ... | 2013 | 23467099 |
| evaluation of the risk of classical swine fever (csf) spread from backyard pigs to other domestic pigs by using the spatial stochastic disease spread model be-fast: the example of bulgaria. | the study presented here is one of the very first aimed at exploring the potential spread of classical swine fever (csf) from backyard pigs to other domestic pigs. specifically, we used a spatial stochastic spread model, called be-fast, to evaluate the potential spread of csf virus (csfv) in bulgaria, which holds a large number of backyards (96% of the total number of pig farms) and is one of the very few countries for which backyard pigs and farm counts are available. the model revealed that, d ... | 2013 | 23465838 |
| a high throughput genotyping approach reveals distinctive autosomal genetic signatures for european and near eastern wild boar. | the lack of a near eastern genetic signature in modern european porcine breeds indicates that, although domestic pigs from the fertile crescent entered europe during the neolithic, they were completely replaced by their european counterparts in a short window of time. whilst the absence of such genetic signature has been convincingly demonstrated at the mitochondrial level, variation at the autosomal genomes of european and near eastern sus scrofa has not been compared yet. herewith, we have exp ... | 2013 | 23460788 |
| in vivo and in situ evaluation of a wireless magnetoelastic sensor array for plastic biliary stent monitoring. | this paper presents the in vivo and in situ evaluation of a system that wirelessly monitors the accumulation of biliary sludge in a plastic biliary stent. the sensing element, located within the stent, is a passive array of magnetoelastic resonators that is queried by a wireless electromagnetic signal. the in vivo and in situ testing uses commercially-available plastic biliary stents, each enhanced with an array of ribbon sensors (formed from metglas™ 2826 mb). the sensor array is approximately ... | 2013 | 23460136 |
| trichinella infections in different host species of an endemic district of serbia. | trichinella infections are endemic in the balkan region of europe. though trichinellosis and agents thereof are serious problems for human health and animal husbandry, only a limited number of trichinella isolates from serbia have been identified at the species level so far. the aim of the present study was the surveillance and monitoring of trichinella in domestic pigs and wild animals from the endemic district of branicevo. investigations performed during the 2009-2010 period revealed trichine ... | 2013 | 23453823 |
| compressive rib fracture: peri-mortem and post-mortem trauma patterns in a pig model. | despite numerous studies on high impact fractures of ribs, little is known about compressive rib injuries. we studied rib fractures from a biomechanical and morphological perspective using 15, 5th ribs of domestic pigs sus scrofa, divided into two groups, desiccated (representing post-mortem trauma) and fresh ribs with intact periosteum (representing peri-mortem trauma). ribs were axially compressed and subjected to four-point bending in an instron 3339 fitted with custom jigs. morphoscopic anal ... | 2013 | 23453778 |
| initial in vivo experience with a novel type of mr-safe pushable coils for mr-guided embolizations. | conventional detachable embolization coils are made from platinum or stainless steel and may thus be a magnetic resonance (mr) safety hazard because of resonant device heating. the objective of this experimental study was to assess the feasibility of mr-guided embolization procedures with a novel type of nonmetallic and, therefore, intrinsically mr-safe pushable coil. | 2013 | 23442773 |
| high prevalence of torque teno sus virus in china and genetic diversity of the 5' non-coding region. | members of the family anelloviridae are emerging circular dna viruses infecting many species of vertebrates including pigs. to date, members of two distinct genera, iotatorquevirus, including torque teno sus virus 1a and torque teno sus virus 1b (ttsuv1a and ttsuv1b), and kappatorquevirus, including torque teno sus virus k2a and torque teno sus virus k2b (ttsuvk2a and ttsuvk2b), have been identified in domestic pigs and wild boars. the goal of this study was to evaluate the prevalence and geneti ... | 2013 | 23435953 |
| bone response to biomimetic implants delivering bmp-2 and vegf: an immunohistochemical study. | this animal study evaluated bone healing around titanium implant surfaces biomimetically coated with bone morphogenic protein-2 (bmp-2) and/or vascular endothelial growth factor (vegf) by examining bone matrix proteins and mineralisation. five different implant surfaces were established: acid-etched surface (ae), biomimetic calcium phosphate surface (cap), bmp-2 loaded cap surface, vegf loaded cap surface and dual bmp-2 + vegf loaded cap surface. the implants were inserted into calvariae of adul ... | 2013 | 23434516 |
| molecular identification of nematode larvae different from those of the trichinella genus detected by muscle digestion. | although larvae of the genus trichinella are the most common parasite species detected in vertebrate muscles using artificial digestion, nematode larvae belonging to other genera are sometimes detected and incorrectly identified as trichinella. however, it is often very difficult to identify these larvae at the species, genus or family level using microscopy because of the absence of specific morphological characters or cuticle damage, and the only means of identification is pcr and sequencing o ... | 2013 | 23433986 |
| lipopolysaccharide-induced inflammation of bronchi and emphysematous changes of pulmonary parenchyma in miniature pigs (sus scrofa domestica). | lipopolysaccharide (lps) is widely used to induce chronic obstructive pulmonary disease (copd) in animal models. rodents are most commonly used to model copd, but their substantial anatomic and physiological differences from humans present a challenge in the research of copd pathogenesis. the authors induced copd in miniature pigs by intratracheal administration of lps solution. they carried out bronchoalveolar lavage (bal) and collected the fluid for analyses of white blood cells, cytokines and ... | 2013 | 23423297 |
| survey of trichinella infections in domestic pigs from northern and eastern henan, china. | the aim of this work was to investigate the current situation of trichinella infections in swine in the cities of anyang and shanqiu in the henan province historically designated as trichinellosis-free. a total of 475 diaphragm muscle samples were collected from 2010 to 2011 and examined by trichinelloscopy and artificial digestion. no trichinella larvae were detected by trichinelloscopy; however, using the digestion method, 3.79% (18/475) of domestic pigs were deemed positive for trichinella. a ... | 2013 | 23422779 |
| shen-fu injection reduces impaired myocardial β-adrenergic receptor signaling after cardiopulmonary resuscitation. | post-resuscitation myocardial dysfunction has been implicated as a major cause of fatal outcome in patients who survive initially successful cardiopulmonary resuscitation (cpr). in our previous study, we found that impaired myocardial β-adrenergic receptor (ar) signaling is a key mechanism in post-resuscitation myocardial dysfunction and shen-fu injection (sfi) can attenuate post-resuscitation myocardial dysfunction. however, whether sfi can prevent impaired post-resuscitation myocardial β-ar si ... | 2013 | 23422192 |
| tamoxifen decreases the myofibroblast count in the healing bile duct tissue of pigs. | the aim of this study was to evaluate the effect of oral tamoxifen treatment on the number of myofibroblasts present during the healing process after experimental bile duct injury. | 0 | 23420165 |
| hepatic and splenic stiffness augmentation assessed with mr elastography in an in vivo porcine portal hypertension model. | to investigate the influence of portal pressure on the shear stiffness of the liver and spleen in a well-controlled in vivo porcine model with magnetic resonance elastography (mre). a significant correlation between portal pressure and tissue stiffness could be used to noninvasively assess increased portal venous pressure (portal hypertension), which is a frequent clinical condition caused by cirrhosis of the liver and is responsible for the development of many lethal complications. | 2013 | 23418135 |
| carbonic anhydrase-related protein xi: structure of the gene in the greater false vampire bat (megaderma lyra) compared with human and domestic pig. | carbonic anhydrase-related protein xi (ca-rp xi) is a member of the α-carbonic anhydrase family (encoded by the gene ca-11), which has lost features of the active site required for enzymatic activity. using pcr, we amplified ca-11 from genomic dna of the bat megaderma lyra. to elucidate the gene structure, we sequenced pcr products and compared their sequences with genomic and mrna sequences known from human and domestic pig. we identified and sequenced eight introns in the bat ca-11. five intro ... | 2013 | 23417223 |
| the foetal pig pineal gland is richly innervated by nerve fibres containing catecholamine-synthesizing enzymes, neuropeptide y (npy) and c-terminal flanking peptide of npy, but it does not secrete melatonin. | innervation of the mammalian pineal gland during prenatal development is poorly recognized. therefore, immunofluorescence studies of the pineals of 70- and 90-day-old foetuses of the domestic pig were performed using antibodies against tyrosine hydroxylase (th), dopamine-β-hydroxylase (dβh), neuropeptide y (npy) and c-terminal flanking peptide of npy (cpon). the investigated glands were supplied by numerous nerve fibres containing th and dβh. the density of these fibres was higher in the distal ... | 2013 | 23408385 |
| species-specific vesicular monoamine transporter 2 (vmat2) expression in mammalian pancreatic beta cells: implications for optimising radioligand-based human beta cell mass (bcm) imaging in animal models. | imaging of beta cell mass (bcm) is a major challenge in diabetes research. the vesicular monoamine transporter 2 (vmat2) is abundantly expressed in human beta cells. radiolabelled analogues of tetrabenazine (tbz; a low-molecular-weight, cell-permeant vmat2-selective ligand) have been employed for pancreatic islet imaging in humans. since reports on tbz-based vmat2 imaging in rodent pancreas have been fraught with confusion, we compared vmat2 gene expression patterns in the mouse, rat, pig and hu ... | 2013 | 23404442 |
| molecular characterization of japanese encephalitis virus strains prevalent in chinese swine herds. | japanese encephalitis virus (jev) is the leading cause of viral encephalitis in asia and domestic pigs serve as the amplifying hosts. in the present study, the full genomic sequences of two jev strains (hen0701 and sh0601) isolated from pigs in china were determined and compared with other 12 jev strains deposited in genbank. these two strains had an 88.8% nucleotide sequence similarity and 97.9% deduced amino acid sequence homology. hen0701 had high nucleotide sequence and high amino acid seque ... | 2013 | 23388434 |
| early detection of acute mesenteric ischemia using diffusion-weighted 3.0-t magnetic resonance imaging in a porcine model. | the aim of this study was to investigate if 3.0-t diffusion-weighted magnetic resonance imaging (mri) can be used for early detection of acute occlusive and nonocclusive mesenteric ischemia. | 2013 | 23385397 |
| determination of organ-specific anemia tolerance. | utilization of anemia tolerance reduces the need for and risks of perioperative transfusion. recent publications indicate that the critical limit for oxygen supply might not be the same for each organ system. therefore, we investigated the effects of acute dilutional anemia on heart, brain, kidneys, liver, small intestine, and skeletal muscle to quantify organ-specific tolerance of different levels of acute anemic hypoxia. we hypothesized that, in some organs, tissue hypoxia occurs before the cr ... | 2013 | 23385097 |
| size-related changes in foot impact mechanics in hoofed mammals. | foot-ground impact is mechanically challenging for all animals, but how do large animals mitigate increased mass during foot impact? we hypothesized that impact force amplitude scales according to isometry in animals of increasing size through allometric scaling of related impact parameters. to test this, we measured limb kinetics and kinematics in 11 species of hoofed mammals ranging from 18-3157 kg body mass. we found impact force amplitude to be maintained proportional to size in hoofed mamma ... | 2013 | 23382967 |
| ischemic post-conditioning and vasodilator therapy during standard cardiopulmonary resuscitation to reduce cardiac and brain injury after prolonged untreated ventricular fibrillation. | we investigated the effects of ischemic postconditioning (ipc) with and without cardioprotective vasodilatory therapy (cvt) at the initiation of cardiopulmonary resuscitation (cpr) on cardio-cerebral function and 48-h survival. | 2013 | 23376583 |
| molecular detection of hepatitis e virus in german domestic pigs. | in industrial countries, hepatitis e virus (hev) transmission to humans is predominantly assumed to be a zoonotic infection. recently, it has been demonstrated that about 50% of domestic pigs in germany carry hev-specific antibodies. however, further investigations concerning the distribution of hev in different age groups of german domestic pigs, phylogenetic analyses and the viral load in the porcine liver are still pending. liver samples of all age groups from herds in a pig-dense region in n ... | 2013 | 23367665 |
| hysteresis in di independent mechanisms in threshold for transition between 1:1 and 2:2 rhythms in pigs. | previous studies have shown hysteresis in transition from 1:1 to 2:2 rhythms in action potential durations (apd) during decreasing and increasing cycle length pacing. as cycle lengths were constant, when alternans of apd occurred, so did of preceding diastolic intervals (dis), which engaged the restitution mechanism, i.e. dependence of apd on preceding di, making it impossible to determine whether the hysteresis originates from the di independent or dependent mechanism. by using pacing with expl ... | 2012 | 23365980 |
| computed tomography-based diagnosis of diffuse compensatory enlargement of coronary arteries using scaling power laws. | glagov's positive remodelling in the early stages of coronary atherosclerosis often results in plaque rupture and acute events. because positive remodelling is generally diffused along the epicardial coronary arterial tree, it is difficult to diagnose non-invasively. hence, the objective of the study is to assess the use of scaling power law for the diagnosis of positive remodelling of coronary arteries based on computed tomography (ct) images. epicardial coronary arterial trees were reconstruct ... | 2013 | 23365197 |
| fluid resuscitation guided by sublingual partial pressure of carbon dioxide during hemorrhagic shock in a porcine model. | to avoid aggressive fluid resuscitation during hemorrhagic shock, fluid resuscitation is best guided by a specific measurement of tissue perfusion. we investigated whether fluid resuscitation guided by sublingual pco2 would reduce the amount of resuscitation fluid without compromising the outcomes of hemorrhagic shock. ten male domestic pigs weighing between 34 and 37 kg were used. forty-five percent of estimated blood volume was removed during an interval of 1 h. the animals were then randomize ... | 2013 | 23364438 |
| high-density dependence but low impact on selected reproduction parameters of brucella suis biovar 2 in wild boar hunting estates from south-western spain. | porcine brucellosis is a disease caused by brucella suis, which is characterized by reproductive disorders in pigs. the number of cases of swine brucellosis has risen in many european countries, likely because of the presence of a wild reservoir of b. suis in wild boar. this study aimed at evaluating factors that may influence the probability of infection with brucella spp. in wild boar and at assessing the impact of a previous contact with brucella spp. on reproductive parameters of wild boar. ... | 2014 | 23347330 |
| research resource: the endometrium database resource (edr). | in order to understand the biology of the endometrium and potentially develop new diagnostic tools and treatments for endometrial diseases, the highly orchestrated gene expression/regulation that occurs within the uterus must first be understood. even though a wealth of information on endometrial gene expression/regulation is available, this information is scattered across several different resources in formats that can be difficult for the average bench scientist to query, integrate, and utiliz ... | 2013 | 23340253 |
| genomic characterization of pseudorabies virus strains isolated in italy. | in this study, we undertook the genomic characterization of 54 pseudorabies virus (prv) strains isolated in italy during 1984-2010. the characterization was based on partial sequencing of the ul44 (gc) and us8 (ge) genes; 44 strains (38 for gene ge and 36 for gc) were isolated on pig farms; 9 originated from dogs and 1 from cattle. these porcine prv strains, which were closely related to those isolated in europe and america in the last 20 years, and the bovine strain bovine/it/2441/1992 belong t ... | 2014 | 23331342 |
| characterization of nuclear localization signal in the n terminus of integrin-linked kinase-associated phosphatase (ilkap) and its essential role in the down-regulation of rsk2 protein signaling. | integrin-linked kinase-associated phosphatase (ilkap) is a serine/threonine (s/t) phosphatase that belongs to the protein phosphatase 2c (pp2c) family. many previous studies have demonstrated that ilkap plays key roles in the regulation of cell survival and apoptosis. researchers have thus far considered ilkap a cytoplasmic protein that negatively regulates integrin signaling by interacting with and phosphorylating integrin-linked kinase 1 (ilk1). in this study, we found that both endogenous and ... | 2013 | 23329845 |
| regions of xy homology in the pig x chromosome and the boundary of the pseudoautosomal region. | sex chromosomes are subject to evolutionary pressures distinct from the remainder of the genome, shaping their structure and sequence content. we are interested in the sex chromosomes of domestic pigs (sus scrofa), how their structure and gene content compares and contrasts with other mammalian species, and the role of sex-linked genes in fertility. this requires an understanding of the xy-homologous sequence on these chromosomes.to this end, we performed microarray-based comparative genomic hyb ... | 2013 | 23320497 |
| a comparison of etanercept vs. infliximab for the treatment of post-arrest myocardial dysfunction in a swine model of ventricular fibrillation. | to compare the effects of two tnf-α antagonists, etanercept and infliximab, on post-cardiac arrest hemodynamics and global left ventricular function (lv) in a swine model following ventricular fibrillation (vf). | 2013 | 23313857 |