Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [acute pericarditis in childhood. the 9-year experience of a tertiary referral center]. | sixteen children, aged 7 months to 12 years, with acute pericarditis, admitted between 1985 and 1993 to a tertiary referral centre were analyzed retrospectively for their presentation, etiology, work-up, management and prognosis. it was found that most of the presenting signs were not specific and were often related to associated diseases such as respiratory tract infections. in 50% of the cases a cause was not found, the others had viral infections (12.5%), tuberculosis (12.5%), haemophilus inf ... | 1997 | 9235847 |
| prevalence of intestinal nematodes of dogs and cats in the netherlands. | faecal samples from 272 dogs and 236 cats from dutch households were examined for nematode eggs. toxocara eggs were found in 8 dogs (2.9%) and 11 cats (4.7%). toxascaris eggs were found in 1 dog (0.4%) and trichuris eggs in 2 dogs (0.7%). examination of faeces from 56 stray cats revealed toxocara in 12 cases (21%) and toxascaris eggs in 3 cases (5.4%). no hookworm eggs were found. the percentage of positive samples was significantly higher in young animals than in older animals. toxocara eggs we ... | 1997 | 9225423 |
| toxocara canis infection and granulomatous hepatitis. | this report describes possible involvement of toxocara canis in granulomatous hepatitis in three patients who presented with varied clinical features; two were being treated for other diagnoses until toxocara serology became available. despite initial nonspecific therapy, there was clinical improvement in all patients and complete resolution of symptoms and abnormal liver biochemistry in two. t. canis infection should be considered in cases of granulomatous hepatitis. | 1997 | 9219807 |
| toxocara canis (nematoda:ascaridae): the fine structure of the oviduct, oviduct-uterine junction and uterus. | the fine structure of the oviduct, oviduct-uterine junction and uterus of the nematode toxocara canis (werner, 1782) is described. columnar-type epithelioid cells with numerous microvilli at the apical membrane border the oviduct lumen. many electron dense secretory products are present in these cells. the cells lining the oviduct-uterine junction have no microvilli. they are coated with an electron-dense layer and contain numerous membrane-bound dense material containing bodies. externally, the ... | 1997 | 9188174 |
| seroepidemiology of five major zoonotic parasite infections in inhabitants of sidoarjo, east java, indonesia. | we conducted a seroepidemiological survey of zoonotic parasite infection in inhabitants of east java, indonesia. the subjects of the survey were 244 persons selected from visitors to sidoarjo city hospital in east java between may 1992 and october 1993. ninety-seven had diarrhea and the rest came to the hospital for routine check-ups. all serum samples were tested for antibodies against five zoonotic parasites: toxoplasma gondii, entamoeba histolytica, toxocara canis. angiostrongylus cantonensis ... | 1996 | 9185269 |
| [toxocara canis infection. 2 cases of peripheral granuloma in adults]. | we report two cases of toxocariasis peripheral granuloma in adults. | 1997 | 9181135 |
| eosinophilia, parasite burden and lung damage in toxocara canis infection in c57bl/6 mice genetically deficient in il-5. | c57bl/6 mice genetically deficient in interleukin (il)-5 (il-5-/-) and mice with the normal il-5 gene (il-5+/+) were infected with embryonated eggs of toxocara canis. il-5+/+ mice developed a marked eosinophilia in their peripheral bloods and bone marrows after infection. in contrast, the number of eosinophils at these sites actually decreased during the acute phase of infection in il-5-/- mice. a smaller number of eosinophils infiltrated the lung, liver, heart and skeletal muscle of infected il ... | 1997 | 9176103 |
| serological evidence of toxocariasis in patients from spain with a clinical suspicion of visceral larva migrans. | sera from patients with clinical characteristics of toxocariasis were assayed using the elisa method and larval excretory-secretory antigen. four hundred and seven samples of toxocara serology were received at the laboratory of ciudad sanitaria juan canalejo hospital of corunna, spain, from 1984 to 1989. of these, 30 were from adults, 332 from children and 45 from patients of unknown age, resulting in toxocara seroprevalences of 23.3%, 32.8% and 17.7% respectively. the reasons for these serologi ... | 1997 | 9166446 |
| primers for polymerase chain reaction to detect genomic dna of toxocara canis and t. cati. | primers for polymerase chain reaction to amplify genomic dna of both toxocara canis and t. cati were constructed by adapting cloning and sequencing random amplified polymorphic dna. the primers are expected to detect eggs and/or larvae of t. canis and t. cati, both of which are known to cause toxocariasis in humans. | 1997 | 9166443 |
| [toxocara infections in childhood in relation to reactive arthritis]. | reactive arthritis belongs to a group of rheumatoid diseases known as seronegative spondylarthritis or spondarthropathies. of many reactive arthritis-evoking agents, the authors focused on larval toxocarosis. the authors describe a child with high anti-toxocara antibody and circulating antigen titres in combination with acute chlamydia infection, which may have caused reactive arthritis in this immunologically impaired organism. this is evidence of the coincidence of different pathological facto ... | 1997 | 9162457 |
| synthesis and nematocidal activity of aralkyl- and aralkenylamides related to piperamide on second-stage larvae of toxocara canis. | seventy-nine aralkyl- and aralkenylamides related to piperamides were synthesized and their nematocidal activity against second-stage larvae of dog roundworm, toxocara canis, was examined. the activity was greatly dependent on the alkyl chain length and the nature of the amine moiety, but was scarcely affected by the presence or absence of double bond(s) in the chain. the alkyl chain lengths which showed the strongest activity in a series of homologues were m = 11 for the pyrrolidine amides and ... | 1997 | 9145505 |
| [a case of toxocariasis]. | 1996 | 9138799 | |
| human toxocariasis and the visceral larva migrans syndrome: correlative immunopathology. | the surface of t. canis is now recognized as a dynamic structure which turns over quite rapidly and serves as a renewable source of large quantities of antigen(s). the major host responses to these antigens include a marked eosinophilia and hyperglobulinemia. both of these responses are apparently ineffective at ridding the body of infective larvae. both eosinphils and ige antibodies are manifestations of the th2 subset of t helper cells and the cytokines that they secrete. further, there is rea ... | 1997 | 9103667 |
| characterization of eosinophil progenitor cells in feline bone marrow. | to identify eosinophil progenitor cells in feline bone marrow, establishing an assay method to use in studies of eosinophilopoiesis and eosinophilopoietic factors in cats. | 1997 | 9099376 |
| diffuse unilateral subacute neuroretinitis. report of transvitreal surgical removal of a subretinal nematode. | the precise identification of nematodes which cause diffuse unilateral subacute neuroretinitis (dusn) has been unsuccessful. shape and size are useful in the initial stages of identification, but histopathologic examination usually is necessary for accurate classification. intact nematodes recovered from patients with dusn have been mentioned scarcely in the literature. the authors report the first case of dusn in which a viable nematode was removed successfully via a transvitreal surgical appro ... | 1995 | 9097745 |
| t-lymphocyte cytokine mrna expression in cystic echinococcosis. | in the present study we investigated cytokine mrna expression by peripheral blood mononuclear cells (pbmc) from patients with cystic echinococcosis (ce) after stimulation with different antigens. by using reverse transcriptase polymerase chain reaction (rt-pcr) we could demonstrate that restimulation with crude echinococcus granulosus antigen (eg-ag) induced or enhanced th2 cytokine mrna expression, especially il-5 (by using antigen from sheep cyst fluid) in 23 out of 26 investigated ce patients ... | 1997 | 9095287 |
| [acute respiratory insufficiency in parasitic eosinophilic pneumonia]. | we report a case of bilateral eosinophilic pneumonia in a 33 year old man. this case developed rapidly into acute respiratory failure and required artificial ventilation. intravenous corticosteroid therapy produced a rapid improvement in the clinical picture. there was hyper-eosinophilia in both the blood and the alveoli which leads to a search for a parasitic aetiology. the different parasitic serologies were negative except for toxocaracanis. the elisa index was strongly positive at 2,597. tre ... | 1997 | 9082509 |
| [visceral larva migrans in adults with severe pulmonary manifestations]. | toxocariosis, the most frequent cause of visceral larva migrans, is usually a disease of children due to ingestion of eggs from the roundworm of dogs (toxocara canis). clinical expression varies from an symptomatic state to fuminant disorders; hepatomegaly with fever is frequent. severe symptoms (rarely in adults) may occur. | 1997 | 9082413 |
| a trichuris specific diagnostic antigen from culture fluids of trichuris suis adult worms. | trichuris suis is a nematode parasite of swine which can cause serious pathology in infected pigs, such as anorexia, diarrhea, anemia, and death in heavy infections, especially in young animals. infection with trichuris suis is difficult to diagnose because much of the pathology occurs when only larval stages are present, and because of sporadic egg production by adult female worms. we have isolated a 20 kda excretory/secretory (e/s) glycoprotein from culture fluids of adult worms by column chro ... | 1997 | 9066055 |
| a serologic study of human toxocariasis in the canary islands (spain): environmental influences. | the presence of anti-toxocara antibodies in the human population of the canarian archipelago was studied by means of an indirect enzyme-linked immunosorbent assay with excretory/secretory antigen of infective-stage larva. a total of 14,074 were analyzed, resulting in the following distribution and prevalence by location: southern tenerife 6,435 (2.5% positive), northern tenerife 1,710 (6.7% positive), la palma 1,214 (4.5% positive), la gomera 264 (6.8% positive), el hierro 204 (3.9% positive), g ... | 1997 | 9063372 |
| [a case of toxocariasis of the eye]. | a case with toxocariasis of the eye is described. the diagnosis was confirmed serologically. vision acuity improved to 100% as a result of treatment. the authors emphasize that toxocariasis should ruled out in all ocular involvements of obscure etiology. | 1996 | 9045495 |
| pulmonary nodules due to toxocara canis infection in an immunocompetent adult. | infection with toxocara canis is well described in the pediatric literature but is reported less commonly in adults. we report a case of t canis infection manifested as abdominal pain with diarrhea, eosinophilia, and diffuse noncavitating nodules in an immunocompetent adult. | 1997 | 9003832 |
| immunological studies on human larval toxocarosis. | the aim of the study was to characterize the antiparasite humoral response in patients with the syndrome of visceral larval toxocarosis. specific igg, specific ige and total ige immunoglobulins against toxocara canis excretory/secretory antigens (tes) were detected by using elisa technique. antibody response was studied in complete sera as well as in immunoglobulin fractions (igg and ige), isolation of which was performed on protein a sepharose. it was observed that removal of igg from the serum ... | 1996 | 8997532 |
| a helminthological survey of wild red foxes (vulpes vulpes) from the metropolitan area of copenhagen. | sixty-eight red foxes were collected from the metropolitan area of copenhagen and examined for helminth infections. standard faecal flotations for intestinal parasites gave the following results: strongyle eggs (75.0%), capillaria eggs (36.8%), toxocara eggs (23.5%), taenia eggs (1.5%), and coccidia oocysts (2.9%). gastrointestinal helminths were collected from 21 of the 68 foxes with the following specimens found: uncinaria stenocephala (85.7%), toxocara canis (81.0%), taenia spp. (38.1%), meso ... | 1996 | 8960222 |
| eosinophilia, il-5 level and recovery of larvae in il-5 transgenic mice infected with toxocara canis. | eosinophil counts, interleukin 5 (il-5) concentrations in peripheral blood and larval recovery after infection with toxocara canis were compared between il-5 transgenic (tg) and nontransgenic counterparts, c3h/hen mice. in tg mice characterized by a constant high level of peripheral eosinophils, eosinophils in peripheral blood fell to the lowest level on day 4 of a t. canis infection and then returned to the preinfection level on day 14. serum il-5 level fell to the lowest level on day 4 of infe ... | 1996 | 8960212 |
| mri of cervical cord lesions and their resolution in toxocara canis myelopathy. | we report serial mri findings in a 58-year-old man with cervical cord involvement by toxocara canis, in whom antihelminthic chemotherapy yielded improvement of the neurological deficits and cord lesions seen on mri. | 1996 | 8957808 |
| ocular toxocariasis in a 36-year-old patient: a case report. | a 36-year-old female presented wit unilateral papillitis, followed by the development of a posterior pole granuloma. a positive elisa-test for toxocara canis with a titer of 1/200 established the diagnosis. the patient was consecutively treated by pars plana vitrectomy and oral corticosteroids. | 1995 | 8936777 |
| investigations into the prevention of neonatal toxocara canis infections in puppies by application of doramectin to the bitch. | the aim of this investigation was to examine whether the treatment of bitches with doramectin is able to prevent pre-natal and galactogenic infections with toxocara canis in their pups. five experimentally infected beagle bitches were treated subcutaneously with 1 mg doramectin per kg body weight on each of days 40 and 55 of their pregnancy. another infected bitch served as an untreated control. the efficacy of the medication was examined by counting the intestinal stages and somatic larvae in b ... | 1996 | 8919967 |
| experimental congenital toxocariasis: effect on foetal future immune response. | congenital parasitic infections may not lead to any overt clinical effects but could modulate the foetal future immune response to the same parasite depending on whether sensitization or tolerance has occurred in utero. in this study, pregnant female mice were infected with toxocara canis eggs at different gestational age, then the offspring were next challenged with toxocara eggs 6 weeks after birth and their immune response was assessed by estimation of the eosinophilic count and serum ige con ... | 1996 | 8918035 |
| seroprevalence of toxocara infection in middle-class and disadvantaged children in northern spain (gipuzkoa, basque country). | the prevalence of human toxocarosis in disadvantaged socioeconomic population in europe is unknown. in gipuzkoa the seroprevalence in middle-class children 2- to 5-years-old, and 6- to 16-year-olds, was zero (n = 135) and 4.4% (n = 320), respectively. in contrast, among socially and economically disadvantaged children the figures were 37% (n = 27) and 65.7% (n = 64). this high prevalence obliges us to consider toxocarosis as a public health problem. | 1996 | 8905319 |
| free and bound biotin molecules in helminths: a source of artifacts for avidin biotin-based immunoassays. | the avidin-biotin molecular recognition system is widely used in parasite immunology. however, the presence of biotin and/or biotin-containing molecules (bcms) in samples may lead to erroneous results. in the work reported herein we investigated the extent to which biotin and bcms present in helminth extracts may interfere in avidin/biotin-based immunoassays and developed an enzyme-linked immunosorbent assay (elisa) for quantification of these components. in avidin-based elisa using antinematode ... | 1996 | 8875569 |
| diagnostic vitrectomy and chronic uveitis. | from the introduction of vitrectomy, infectious endophthalmitis was one of the indications for this surgical technique. vitrectomy was later found to be a valuable method in both diagnostic and therapeutic evaluation of chronic uveitis. | 1996 | 8871142 |
| seroprevalence of toxocariasis in children and a case of vlm. | an epidemiological study on toxocariasis in children was carried out at our hospital (madrid, spain) in relation with a case of toxocariasis in a child with chronic hypereosinophilia. the study was based on a positive result of the elisa test, using excretory-secretory antigen from toxocara canis. the seroprevalence in children was 1%. | 1995 | 8861856 |
| effect of glucan immunomodulator on the immune response and larval burdens in mice with experimental toxocarosis. | glucan immunomodulator, combined with immunoglobulin and zinc (gi), was tested in mice infected with toxocara canis for its effects on the immune response and parasite recovery. infection with 2 500 t. canis eggs per mouse induced a short-term depression of the proliferative response of t cells to phytohemaglutinin from day 35 to a day 49 post infection (p.i.). gi given in two doses at the start of the experiment markedly stimulated and restored cell proliferation at days 21-63 p.i. infection re ... | 1996 | 8856944 |
| [toxocariasis. a cosmopolitan parasitic zoonosis]. | the infection by toxocara canis transmitted by dogs (30% of them are infected in our countries) and less frequently by cats lead to larva migrans visceral syndrome with neurological manifestations, ophtalmological affection and various cutaneous manifestations observed in 24% of the extra-ocular infections: chronic urticaria often associated with asthmatic manifestations and chronic rhinitis, angio-oedema or local oedema reaching particularly the eyclid, chronic pruritus associated with lesions ... | 1995 | 8851035 |
| antigen induced eosinophilia protects gerbils (meriones unguiculatus) against experimental amebic abscess of the liver. | while the normal human eosinophil is destroyed in vitro by virulent entamoeba histolytica, notwithstanding the presence of antibodies and complement, activated eosinophils promptly destroy the parasite even though succumbing in the process as well. to study the possible in vivo participation of eosinophils in invasive amebiasis, we compared the induction of experimental amebic abscess of the liver (eaal) in gerbils (meriones unguiculatus) previously made eosinophilic (532 +/- 80 eosinophils/mm3) ... | 1995 | 8845666 |
| b cell mitogenic activity of toxocara canis adult worm antigen. | the effect of toxocara (t.) canis antigen (tcag) on lymphocytes was studied in vitro using normal murine spleen cells and human peripheral blood lymphocytes. tcag prepared from adult worms stimulated murine spleen cells to proliferate at concentrations of 1-125 micrograms/ml. the responder cells tcag are b cells, because the response was depleted by the treatment of spleen cells with anti-immunoglobulin (ig) antibody and complement and after separation on a nylon wool column. this response was n ... | 1995 | 8834760 |
| [toxocariasis syndrome as a cause of hypereosinophilia]. | the study described two cases of toxocariasis characterized by the presence of large numbers of large number of eosinophils. the authors emphasized the fact of necessity to make serologic tests in every patient with hypereosinophilia. | 1995 | 8834662 |
| intestinal helminths of the red fox (vulpes vulpes l.) in galicia (northwest spain). | the intestinal helminth fauna of 201 specimens of vulpes vulpes, captured in galicia (northwest spain), was investigated. eight species were found: toxocara canis (23% of host specimens), toxocara cati (0.5%), toxascaris leonina (1%), uncinaria stenocephala (28%), seuratascaris numidica (0.5%), taenia crassiceps (23%), mesocestoides litteratus (2.5%) and dipylidium caninum (0.5%). we discuss possible relationships between human population density and the prevalence of infection of fox by intesti ... | 1995 | 8834508 |
| ocular toxocariasis. | toxocara canis is a preventable cause of intraocular inflammation and visual loss ... caused by the larvae of toxocara canis usually occurring in children and young adults following accidental ingestion of the larvae from infected dogs. treatment of ocular toxocariasis can include a combination of cryopexy and photocoagulation, with vitrectomy surgery utilized in the more serious cases. | 1995 | 8826357 |
| toxocara titres in maternal and cord blood. | fifty-two pairs of maternal and cord blood samples were examined for evidence of toxocara canis antibodies. all the mothers in the study delivered normal babies at term. seventeen (33%) of the mothers had toxocara antibody titres of 1:50 or greater. no igm isotype anti-toxocara antibody was detected in the cord blood samples, evidence that transplacental toxocaral infection had not occurred. in the toxocara antibody-positive group it was found that six of 17 mothers (35%) had previously miscarri ... | 1996 | 8793714 |
| visceral larva migrans. | 1995 | 8772881 | |
| [visceral larva migrans: a mixed form of presentation in an adult. the clinical and laboratory aspects]. | we relate a case of an 18-year-old man, resident of xapuri (state of acre, brazil), with a history of repeated episodes of meningoencephalitis (three in one year), each one was examined by a local doctor. in our service (emílio ribas institute of infectology) we observed a patient with polyjoint aches, radiological and bronchoscopic pulmonary alterations (without clinical features), meningeal and brain stem manifestations--with normal brain computed tomography and cerebrospinal fluid. blood eosi ... | 1996 | 8768588 |
| [chronic urticaria and toxocara canis infection. a case-control study]. | the cause of chronic urticaria remains unknown very often. having noted several cases of chronic urticaria associated with antibodies to toxocara canis, and lacking any other explanation, we set-up a case-control study. | 1996 | 8763746 |
| [intestinal geohelminthosis in man and domestic animals in the riverside sections of the valdivia river basin, chile]. | in march-october 1987 were analyzed 1295 coprological specimens in a sample of the human population who lives in riverside localities in the valdivia river basin, chile. a 23.6% of examined persons presented infection by one or more helminth species. the prevalence of infection by ascaris lumbricoides, trichuris trichiura and trichostrongylidae gen. sp. were 15.5, 12.7 and 0.2%, respectively. the prevalence of human ascariosis and trichuriosis were greater in pre-school and school children. the ... | 1995 | 8762668 |
| [phosphocholine antigens in muscle larvae of trichinella spiralis]. | crude t. spiralis larval antigens often cross-react with antibodies to other parasites (for instance toxocara canis) in the elisa test. the crossreactivity of the sera is probably due to the presence of phosphocholine (pc)-specific antibodies to antigens found in the inner layer of the cuticle, in the haemolymph, genital primordium and glycogen aggregates t. spiralis larvae. the anti-pc response following infection with t. spiralis occurs earlier than the antispecific antigens response. the abov ... | 1996 | 8755146 |
| effect of some parasitic infection on neurotransmitters in the brain of experimentally infected mice before and after treatment. | the effects of some parasitic infection (bilharziasis, toxocariasis and trichinosis) on the brain of experimentally infected mice were investigated. eighty animals were classified into four groups, group i contained five non infected animals as a control group. the other groups each contained twenty-five mice infected with schistosoma mansoni (group ii), toxocara canis (group iii) and trichinella spiralis (group iv). each infected group was divided into two subgroups (a,b). subgroup (a) left unt ... | 1996 | 8754657 |
| eosinophil peroxidase deficiency in new zealand white mice. | eosinophil peroxidase (epo) is one of the granule enzymes in the eosinophil-specific granules and is distinct from myeloperoxidase. here we report that peroxidase activity was absent in eosinophils of new zealand white (nzw) mice. when nzw, new zealand black and their f1 mice were treated with cyclophosphamide followed by toxocara canis infection, the kinetic changes in the number of eosinophils in peripheral blood, determined by counting in hinkelman's diluting fluid, were almost comparable amo ... | 1996 | 8753841 |
| [hepatic toxocariasis]. | 1995 | 8749411 | |
| antigenic cross-reactivity in mice between third-stage larvae of anisakis simplex and other nematodes. | we used elisa and immunoblotting to investigate antigenic cross-reactivity in mice between third-stage larvae of anisakis simplex and five other nematodes: the ascaridoids ascaris suum, toxocara canis and hysterothylacium aduncum, and the nonascaridoids trichinella spiralis and trichuris muris. two sera were raised against each species (including a. simplex, but excluding a. suum), by infection or by immunization with somatic antigens. serum against a. suum was raised by immunization only. the r ... | 1996 | 8740558 |
| parasitic causes of hepatomegaly in children. | three hundred children with hepatomegaly were selected. they were subjected to full clinical and laboratory examinations. also serum samples were examined to detect igg using elisa against sea, chromatography purified hydatid cyst antigen, commercially available toxoplasma antigen, partially purified adult fasciola antigen and second-stage larvae toxocara canis antigen. ifat was used to detect igg against toxoplasma and t. canis. a commercially available ihat kit for leishmaniasis was used. base ... | 1996 | 8721239 |
| toxocara canis infection in preschool age children: risk factors and the cognitive development of preschool children. | risk factors for toxocara canis (t. canis) infection were evaluated in a prospective study of disadvantaged preschool children. in addition, the hypothesis that t. canis exposure is associated with lower intelligence was tested. seropositivity was tested at 2 years, 3 years, and at 4 years 10 months (4-10). intelligence was measured at age 4-10 by the full scale iq of the wechsler preschool and primary scales of intelligence (wppsi). pica and ownership of a dog were unrelated to seropositivity. ... | 1996 | 8709928 |
| some epidemiologic features of canine neosporosis in denmark. | from a serological survey of 98 dogs, the overall prevalence of subclinical neosporosis among dogs in denmark was estimated as 15.3%. from a questionnaire completed at the time of blood sampling in 87 dogs, it was found that exposure to cats could be a risk factor for the infection in dogs (odds ratio 3.46; 95% confidence limit 1.1-11.4). further, it was shown that the antibody response in a pregnant dog increased markedly during gestation, suggesting that the parasite may be reactivated during ... | 1996 | 8686180 |
| diagnostic parasitology. | 1996 | 8681293 | |
| toxocara canis-induced airway eosinophilia and tracheal hyporeactivity in guinea pigs and mice. | guinea pigs and mice infected with the parasitic worms toxocara canis developed airway inflammation and tracheal hyporesponsiveness. preceding inflammatory cell infiltration a brief hyperreactive response occurred in guinea pigs to histaminergic receptor stimulation at 3 days post infection (p.i.) and in mice to acetylcholine receptor stimulation at 1 day p.i. few but large eosinophilic inflammatory foci developed in guinea pigs at 14 days p.i. mice demonstrated progressive multifocal inflammati ... | 1995 | 8666037 |
| pleural effusion and toxocariasis. | the case history is described of a woman who presented with bilateral pleural effusions caused by toxocara canis infestation. the condition responded rapidly to treatment. | 1996 | 8658358 |
| an abundantly expressed mucin-like protein from toxocara canis infective larvae: the precursor of the larval surface coat glycoproteins. | evasion of host immunity by toxocara canis infective larvae is mediated by the nematode surface coat, which is shed in response to binding by host antibody molecules or effector cells. the major constituent of the coat is the tes-120 glycoprotein series. we have isolated a 730-bp cdna from the gene encoding the apoprotein precursor of tes-120. the mrna is absent from t. canis adults but hyperabundant in larvae, making up approximately 10% of total mrna, and is trans-spliced with the nematode 5' ... | 1996 | 8643687 |
| eosinophil chemotactic activity in bronchoalveolar lavage fluid obtained from toxocara canis-infected rats. | we examined eosinophil chemotactic activity (eca) in bronchoalveolar lavage fluid (balf) obtained from rats infected with toxocara canis. for 4 weeks after infection, the number of eosinophils was determined in peripheral blood and balf. eca was assayed using a microchemotaxis chamber. eosinophils in peripheral blood and balf increased markedly after infection, peaking at 12 days and 2 weeks, respectively. eca in balf also increased significantly and peaked 2 weeks after infection. partial chara ... | 1996 | 8605701 |
| incidence of toxoplasma and toxocara antibodies among out-patients in the ophthalmic research institute, egypt. | infection by toxoplasma gondii and toxocara canis is getting much important nowadays. both are soil transmitted infections. the present study was planned to detect the incidence of t. gondii and t. canis antibodies among 100 patients attending the outpatient clinics in research institutes of ophthalmology (rio), whose urine and stool were free from other parasitic stages. patients were classified into two groups, group i; (70 ocular cases) and group ii, (30 non-occular cases). control group (gro ... | 1995 | 8586877 |
| comparative sds-page protein patterns of four ascaridid nematodes. | in order to investigate the degree of homogeneity and heterogeneity of the ascaridid nematodes. toxascaris leonina, parascaris equorum, toxocara canis and t. vitulorum, protein extracts from adult worms of the four nematodes were resolved into a number of bands. comparative analysis of dominant bands showed that 13 bands were common among the four species, but certain unique bands were also found in each species including 4 in t. vitulorum, one in t. leonina, two in t. canis, while p. equorum sh ... | 1995 | 8586870 |
| [identification of toxocara canis larvae in ocular granuloma]. | 1994 | 8560840 | |
| specific igg1 and igg2 antibody responses of dogs to leishmania infantum and other parasites. | sera from dogs naturally infected with leishmania infantum were analysed for the igg subclass specificity of their antibody response by elisa. dogs infected with l. infantum produced both igg1 and igg2 antibodies with igg2 being associated with asymptomatic infections and igg1 being associated with disease (symptomatic dogs, non- or low-responsive to chemotherapy). the differential responses of igg1 and igg2 serum antibodies in asymptomatic and symptomatic dogs may indicate a dichotomous immune ... | 1995 | 8552413 |
| evaluation of mebendazole activity on experimental murine toxocariasis by immune complexes determination. | the mebendazole action on experimental murine toxocariasis, using different formulations and vehicles, was studied by means of the detection of antibodies and immune complexes by elisa. after inoculation with 1000 embryonated toxocara canis eggs, balb/c mice were submitted to the anthelmintic treatment as follows: group 1 (control without treatment); group 2 (mebendazole (mbz), lomper, steve laboratories, barcelona, spain, suspended in 1% sodium carboxymethylcellulose (cmc) at a dose of 100 mg/k ... | 1995 | 8546022 |
| index of suspicion. case 1. toxocara canis and ascaris infection with lead poisoning]. | 1995 | 8539194 | |
| persistence of specific antibody response in different experimental infections of mice with toxocara canis larvae. | anti-toxocara antibody production and persistence were studied in experimental infections of balb/c mice, according to three different schedules: group i (gi)-25 mice infected with 200 t. canis eggs in a single dose; group ii (gii) 25 mice infected with 150 t. canis eggs given in three occasions, 50 in the 1st, 50 in the 5th and 50 in the 8th days; group iii (giii)-25 mice also infected with 150 t. canis eggs, in three 50 eggs portions given in the 1st, 14th and 28th days. a 15 mice control grou ... | 1995 | 8525261 |
| a cdna encoding ribosomal protein l3 from the parasitic nematode toxocara canis. | a cdna encoding the ribosomal (r) protein l3 of the parasitic nematode toxocara canis was isolated from a library constructed from mrna of the infective larval stage. the encoded protein has a high degree of similarity to r-protein l3 from other organisms, including mammals, yeast, plants and bacteria. the mrna encoding r-protein l3 is derived from a single-copy gene, and experimental evidence would suggest that it contains the pan-nematode splice leader sequence at its 5' end and that the gene ... | 1995 | 8522183 |
| the art of parasite survival. | parasites develop and survive in an environment which is often hostile to them. when facing aggressive conditions parasites are able to use various and complex strategies. echinococcus granulosus, toxocara canis, pneumocystis carinii, entamoeba or toxoplasma gondii are able to seclude from the environment when stressed by surrounding (immunologic or non-immunologic) aggressive factors. specific antigens which exert a functional activity during a short period of time appear to be concealed from t ... | 1995 | 8520537 |
| prevalence of toxocara eggs and number of faecal deposits from dogs and cats in sandpits of public parks in japan. | contamination of 13 sandpits in public parks in hyogo prefecture, japan, by toxocara eggs and animal faeces was studied. all 13 sandpits were contaminated with faeces. the mean number of faeces found in 1 m2 of the sandpits was 35, from which the number of faeces in each sandpit was estimated to be 261 to 2205. toxocara eggs were detected in 12 of the 13 sandpits, each examined 4-15 times; the overall prevalence was 92%. the eggs were not always distributed in the same pattern, but in general, e ... | 1993 | 8509622 |
| efficacy of fenbendazole and piperazine against developing stages of toxocara and toxascaris in dogs. | in a series of controlled trials involving 59 naturally infected greyhounds, fenbendazole at a dose rate of 50 mg/kg/day for three consecutive days reduced the overall numbers of third and fourth stage toxocara canis by 94.0 per cent and third stage, fourth stage and immature adult stages of toxascaris leonina by 92.4 per cent. in contrast, piperazine at 100 mg/kg had little or no useful effect against the larval stages of t canis and t leonina and variable efficacy against immature adult t leon ... | 1993 | 8506598 |
| ocular toxocariasis in a patient with repeatedly negative elisa titre to toxocara canis. | 1993 | 8494866 | |
| "covert toxocariasis" in a child treated with low-dose diethylcarbamazine. | a girl aged 2.5 years with "covert toxocariasis" was treated with low-dose diethylcarbamazine because of supposed noticeable disseminated toxocara canis infection without ocular or visceral manifestations. there was marked blood and bone marrow eosinophilia, significant increased toxocara canis antibody (elisa) and immunoglobulins e, g and m, leucocytosis and an increased sedimentation rate. she had no geophagia, but often sucked small stones, probably contaminated with faeces from puppies. symp ... | 1993 | 8453208 |
| isolation of feline eosinophils via peritoneal lavage. | fourteen cats were inoculated orally with 1 of 2 infective doses of toxocara canis to induce eosinophilia. cats were subsequently challenge exposed twice via intraperitoneal injection with 1 of 2 t canis antigen preparations. peritoneal lavage was performed 2 days after antigenic challenge exposure, and eosinophils in the peritoneal lavage fluid were quantified. none of the cats developed clinical signs of disease after infection. all cats developed peripheral eosinophilia after infection. signi ... | 1993 | 8430932 |
| epidemiology of toxocara canis in red foxes (vulpes vulpes) from urban areas of bristol. | a descriptive epidemiological survey was undertaken of the ascarid nematode toxocara canis in 521 red foxes (vulpes vulpes) during the period january 1986 to july 1990. age-prevalence and age-intensity profiles show that worm burdens are significantly higher in cubs than in subadult or adult foxes and higher in subadult than in adult foxes. seasonal variations in worm burdens occur, with the highest prevalences and intensities being found during the spring, when cubs are born, and in the summer ... | 1993 | 8414671 |
| [cerebral immune vasculitis as a complication of larva migrans infection caused by toxocara canis]. | 1993 | 8377723 | |
| [toxocara canis associated with splenic rupture]. | 1993 | 8362150 | |
| [toxocariasis. a rare disease or rarely recognized?]. | 1993 | 8362145 | |
| visceral and ocular larva migrans. | 1993 | 8356352 | |
| parasites of the arctic fox (alopex lagopus) in iceland. | forty-four of 50 arctic foxes (alopex lagopus) in iceland harbored 15 species of intestinal parasites, including protozoa: eimeria sp. or isospora sp. (in 4%); trematoda: cryptocotyle lingua (24%), plagiorchis elegans (4%), brachylaemus sp. (12%), tristriata sp. (10%), and spelotrema sp. (8%); cestoda: mesocestoides canislagopodis (72%), schistocephalus solidus (2%), and diphyllobothrium dendriticum (4%); nematoda: toxascaris leonina (50%), toxocara canis (2%), uncinaria stenocephala (4%), and e ... | 1993 | 8355346 |
| changing chemosusceptibility in the second-stage larvae of toxocara canis by long-term incubation. | second-stage larvae of toxocara canis were maintained in vitro for one year. susceptibility of the larvae to drugs was evaluated by means of minimal larvicidal concentration (mlc) and larval bursting percentage. mlcs of citral and decanoic acid were almost constant throughout all stages of incubation. however, bursting percentage markedly varied within the first 20 weeks of incubation. therefore, while larvae are available for use in the mlc assay at any stage of incubation, those beyond the fir ... | 1993 | 8354860 |
| diagnosis of human toxocariasis by antigen capture enzyme linked immunosorbent assay. | to evaluate an antigen capture enzyme linked immunosorbent assay (elisa) which detects a carbohydrate epitope on the excretory-secretory (es) antigens of toxocara canis in clinical practice. | 1993 | 8331180 |
| toxocara canis: failure to find ige receptors (fc epsilon r) on eosinophils from infected mice suggests that murine eosinophils do not kill helminth larvae by an ige-dependent mechanism. | eosinophils obtained by bronchoalveolar lavage (bal) from the lungs of mice infected with toxocara canis were characterized by flow cytometry with respect to cytophilic antibodies and surface fc receptors. freshly harvested bal eosinophils were negative for sigm, siga, sige, and fc epsilon rii. these eosinophils were positive for sigg1 and fc gamma rii, although not all fc gamma riis contained bound ligand. culturing eosinophils for 24 or 48 hr with exogenous ige and/or il-4 did not induce ige b ... | 1994 | 8299761 |
| ocular toxocariasis in children and youth. | the number of infections with larvae of the toxocara canis worm has been continuously increasing in the polish population, and the diagnosis and treatment of this disease is difficult. the authors describe 81 cases of eye infection in children and youth at the age of 3 to 18 years. the lesions in 94 eyes were observed for 0.5 to 11 years. in all patients the diagnosis was confirmed by elisa test. in the clinical picture various forms of uveitis and granuloma of the eye fundus were found. the tre ... | 1993 | 8299505 |
| prevalence of toxocara eggs in sandpits in tokushima city and its outskirts. | to demonstrate the prevalence of toxocara eggs in sandpits in tokushima prefecture, japan, sand samples were examined. of 46 sandpits surveyed, 29 sandpits (63.3%) had toxocara eggs. sandpits in public parks and playgrounds in residential areas were more contaminated (87.5%) with the eggs than those in kindergartens, schools, and children's centers (36.4%). to examine the seasonal change in the contamination, sand samples obtained from five sandpits were examined monthly from may 1990 to april 1 ... | 1993 | 8286535 |
| [the infection risk for dogs raised helminth-free in conventional conditions in an urban area]. | the present investigations were carried out to clarify whether or not and to what extent helminth-free raised dogs acquire patent and impatent helminth infections when exposed to an urban area contaminated with dog faeces. groups of each 3 bitches at an age of 3, 6 or 9 months were taken out to an urban area (with average dog density of 1.5 per ha) for 3 hours daily on 5 days per week for a period of 3 month. during the whole trial the bitches and puppies born during this period were maintained ... | 1993 | 8284959 |
| effects of pyrantel pamoate on adult and preadult toxocara canis worms: an electron microscope and autoradiography study. | adult as well as preadult toxocara canis isolated from the intestine of a beagle were incubated for 2, 4, and 14 h in medium containing either different concentrations of pyrantel pamoate (23.6, 236, and 2360 micrograms/ml medium) or tritiated pyrantel pamoate (2.36 micrograms/ml medium). these incubations were performed to study the effects of pyrantel pamoate on the morphology of the parasitic nematodes and to obtain information concerning the mode of uptake, the distribution, and the total am ... | 1993 | 8278339 |
| comparable seropositivity for ascariasis and toxocariasis in tropical slum children. | the seropositivities for infection by ascaris lumbricoides and toxocara canis were determined in children (1-15 years old) of a slum area of caracas, venezuela, and the levels that indicate the presence of active infection were defined. in children aged from 1 to 3 years, approximately 10% were positive for either parasite, and this figure increased to about 30% in 4- to 6-year-olds. for toxocariasis, the percentage of positivity remained at this level up to the age of 15 years. whilst the posit ... | 1993 | 8278336 |
| serosurvey of some major zoonotic infections in children and teenagers in bali, indonesia. | one hundred and ninety serum samples, mainly from children and teenagers, from northeast bali were tested for the presence of antibodies against five zoonotic agents: brucella abortus, coxiella burnetii, toxoplasma gondii, toxocara canis and trichinella spiralis. all children were negative for brucellosis and q fever. a high prevalence rate was found for toxocariasis (63.2%) and trichinosis (19.5%). antibody prevalence against t. gondii was found to be rather low (3.1%). to our knowledge, this i ... | 1993 | 8266236 |
| [parasitological fecal studies of equids, dogs, cats and hedgehogs during the years 1984-1991]. | the results of the coproscopical examinations in horses, dogs, cats and hedgehogs between 1984 and 1991 are presented. in 9192 samples from horses 55.5% stages of strongylids, 4.0% of parascaris equorum, 2.2% of anoplocephalids, 1.6% strongyloides westeri, 0.7% of oxyuris equi, 0.6% of eimeria leuckarti, 0.2% of fasciola hepatica and 0.04% of dictyocaulus arnfieldi were found. in 48.0% of the 46 samples from donkeys eggs from strongylids were detected, in 17.4% larvae from dictyocaulus arnfieldi ... | 1993 | 8261912 |
| zoonotic roundworm infections. | the larval stage of several animal parasites can infect humans and produce severe disease. visceral and ocular larval migrans caused by the common dog roundworm, toxocara canis, are two well-recognized clinical syndromes. with the wider availability of serodiagnostic tests for toxocaral infection, other syndromes characterized by neuropsychologic deficits, epilepsy, asthma, abdominal distress, and chronic allergy have been described. treatment with corticosteroids in conjunction with anthelminth ... | 1993 | 8254168 |
| the spectrum of ocular toxocariasis. | ocular toxocariasis is rare and therefore the spectrum of clinical disease is difficult to establish. we present a review of the clinical features and laboratory findings in a group of patients with positive toxocara serology and ocular toxocariasis. the clinical spectrum was diverse and milder disease was commoner than might be supposed from reviews of the literature. eosinophilia was unusual, but featured in two cases of unilateral pars planitis. | 1993 | 8224297 |
| eosinophilic meningoencephalitis due to toxocara canis. | 1993 | 8223820 | |
| nematocidal activity of turmeric: synergistic action of curcuminoids. | a new curcuminoid, cyclocurcumin (iv), was isolated from the nematocidally active fraction of turmeric, the rhizome of curcuma longa, together with three known curcuminoids, curcumin (i), demethoxycurcumin (ii) and bisdemethoxycurcumin (iii). the structure of iv was elucidated on the basis of spectral data and confirmed by the partial synthesis from curcumin (i). although the above curcuminoids were ineffective when they were applied independently, the nematocidal activity increased remarkably w ... | 1993 | 8221978 |
| [toxocara ova in parks and sand-boxes in the city of utrecht]. | an investigation was carried out for the presence of toxocara spp. eggs in public parks and children's sand-boxes in the city of utrecht. the pollution of parks with the eggs of the dog's ascarid toxocara canis is comparable with reports from other european cities. the eggs of toxocara cati were found in small numbers only. interestingly there was no difference between parks with or without formal exclusion of dogs. most sand-boxes are polluted with the eggs of the ascarid of cats t. cati. incid ... | 1993 | 8211920 |
| parasitism of toxocara canis larvae in chickens inoculated with the ascarid eggs. | the distribution of t. canis larvae and pathological changes of the liver caused by them were studied in chickens inoculated orally with 1,500 embryonated eggs during 1 and 50 days after inoculation. the number of larvae recovered varied from 40 to 192 in the liver, 8 to 166 in the muscles, 0 to 4 in the heart, 0 to 2 in the spleen, 0 to 1 in the brain, respectively. small white foci were observed on the surface of the liver since 6 days after inoculation. histopathological examination of the li ... | 1994 | 8204739 |
| toxocara canis infection presenting as eosinophilic ascites and gastroenteritis. | eosinophilic ascites is rarely observed in clinical practice. it may be associated with the serosal type of eosinophilic gastroenteritis, abdominal lymphoma, hypereosinophilic syndrome, or peritoneal dialysis but is uncommonly related to parasitic infections. we report a case of a previously healthy young patient who developed diarrhea and exudative eosinophilic ascites. the final diagnosis was consistent with a parasitic infection due to toxocara canis, while the clinical and radiological findi ... | 1994 | 8200273 |
| [utilization of elisa ige method in diagnosis of toxocariasis in humans]. | in order to improve the immunodiagnosis of toxocariasis, an immunoenzymatic assay (elisa) with excretory-secretory antigens from toxocara canis larvae was developed for the detection of specific immunoglobulin e. titers of ige were lower than those of igg in the same samples, however ige elisa appeared to be more specific. ige elisa might be an interesting complementary method in the diagnosis of toxocariasis. | 1993 | 8189832 |
| intestinal helminths of public health importance in dogs in nairobi. | in a survey of intestinal canine zoonotic helminths in nairobi, 156 dogs were autopsied. of these, 10% were infected with echinococcus granulosus, 88% with ancylostoma caninum, 45% with dipylidium caninum and 3% with toxocara canis. all the infected dogs with e. granulosus originated from around abottoirs in dagoretti. the risk of infection in man with hydatid disease is considered to be high around dagoretti and control measures are recommended. | 1993 | 8187655 |
| elisa seropositivity for toxocara canis antibodies in malaysia, 1989-1991. | the laboratory test results for visceral larva migrans (vlm) using elisa for toxocara canis antibodies employed by the institute for medical research, kuala lumpur, is described. a total of 331 serum samples received from hospitals and general practitioners all over malaysia were tested. the test utilises excretory-secretory antigens obtained from in vitro culture of second stage t. canis larvae. the overall seropositivity rate was 19.6%, the highest positive rate being in indians (35.5%), follo ... | 1993 | 8183143 |
| toxocara canis-induced murine pulmonary inflammation: analysis of cells and proteins in lung tissue and bronchoalveolar lavage fluid. | the pulmonary immuno-inflammatory reaction and its effect on microvascular integrity was studied in toxocara canis infected balb/c mice. the investigation aimed to compare changes in lung histology and composition of bronchoalveolar lavage fluid (balf) caused by t. canis infection with those described to occur in allergic asthma. groups of (non)-infected mice (1000 ova) were investigated until 90 days post infection (p.i.). migration of the larvae through the lungs was followed by a rapidly prog ... | 1994 | 8152829 |
| hepatic visceral larva migrans: evolution of the lesion, diagnosis, and role of high-dose albendazole therapy. | an unusual presentation of hepatic involvement of visceral larva migrans is described. a 45-yr-old male presented with fever, pain in the right upper quadrant, and persistent eosinophilia. ultrasound initially detected a solitary hypoechoic area in the right lobe of the liver which rapidly progressed to multiple lesions with peripheral hyperechoic lesions. aspiration from the lesion revealed charcot-leyden crystals and sheets of eosinophils. serology for toxocara canis was strongly positive. pro ... | 1994 | 8147371 |