Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| the biotyping of escherichia coli isolated from healthy farm animals. | a total of 2973 escherichia coli, isolated from six different groups of animals, were examined for their ability to ferment adonitol, dulcitol, raffinose, rhamnose and sorbose in solid media. twenty-nine fermentation patterns were recorded although 2443 (82%) of the e. coli belonged to seven of the 32 possible biotypes. ninety-six o-serotypes were identified within the 2973 e. coli. the number of o-serotypes represented in the 15 most common biotypes ranged from three to 15. serotypes o8 and o9 ... | 1982 | 7045219 |
| [model for in vivo study of antibiotics efficacy and level of escherichia coli implantation in the digestive tract (author's transl)]. | 1981 | 7044257 | |
| rat preprorelaxin: complete amino acid sequence derived from cdna analysis. | 1982 | 7044231 | |
| [development of experimental keratoconjunctivitis as affected by the combined action of microbial agents and penicillin]. | 1982 | 7043982 | |
| pulmonary dysfunction in sepsis: is pulmonary edema the culprit? | pulmonary dysfunction is a well-recognized sequela of sepsis, which has been quantitated by calculation of intrapulmonary shunt (qs/qt) and, more recently, by measurement of extravascular lung water (evlw). we sought to demonstrate the relationship between qs/qt and evlw in sepsis. nine pigs were given live e. coli infusions and five control pigs received only crystalloid. pulmonary artery pressure (pap), pulmonary artery wedge pressure (pawp), arterial blood gases (abg), and mixed venous blood ... | 1982 | 7042992 |
| effect of immunising pregnant sows with different escherichia coli vaccines on the antibody levels in the piglet sera. | six groups of pregnant sows were immunised with four different commercial escherichia coli vaccines. five groups were vaccinated parenterally while the other group was vaccinated orally and then parenterally. the colostral antibody titres to e coli o149 k91(b) k88 as measured by indirect haemagglutination were significantly higher in the vaccinated sows than in the controls. oral priming by vaccine feeding as opposed to parenteral administration did not appear to produce an anamnestic response. ... | 1981 | 7041409 |
| gm1 ganglioside enzyme-linked immunosorbent assay for detection of heat-labile enterotoxin produced by human and porcine escherichia coli strains. | human and porcine enterotoxigenic strains of escherichia coli were cultivated in tryptone-yeast extract medium or brain heart infusion broth and tested for production of heat-labile enterotoxin by the gm1 ganglioside enzyme-linked immunosorbent assay (gm1-elisa) and the y1 adrenal cell assay. when testing for enterotoxigenicity by the gm1-elisa technique, homologous antisera for human and porcine heat-labile enterotoxins had to be used to detect enterotoxigenic strains of human and porcine origi ... | 1982 | 7040450 |
| protection against colibacillosis in neonatal piglets by immunization of dams with procholeragenoid. | protection against colibacillosis in neonatal piglets was obtained by immunization of pregnant dams with procholeragenoid. procholeragenoid is a stable high-molecular-weight aggregate of cholera toxin formed during the heating of cholera toxin. procholeragenoid retained approximately 1% of the toxicity of native toxin as determined in the rabbit ileal loop and y-1 adrenal cell assays and 5% of the activity in the rabbit skin assay. immunization of pregnant dams with 50 micrograms of procholerage ... | 1982 | 7040250 |
| dietary manipulation of gastric ph in the prophylaxis of enteric disease in weaned pigs: some field observations. | 1981 | 7039079 | |
| escherichia coli-associated porcine neonatal diarrhea: antibacterial activities of colostrum from genetically susceptible and resistant sows. | antibacterial properties of colostrum from genetically resistant and susceptible sows in a herd in which only the susceptible sows had acquired natural immunity to k88-positive escherichia coli have been investigated. significant differences in antiadhesive and opsonic activities occurred. colostrum from susceptible sows inhibited the binding of 125i-labeled k88 antigen to brush borders significantly better than did the colostrum from resistant dams. colostrum from susceptible dams effected more ... | 1982 | 7035361 |
| effect of pectin on secretion in pig jejunal loops challenged to enteropathogenic e. coli or enterotoxin (lt). a preliminary report. | perorally administered pectin in pigs could reduce the fluid accumulation in intestinal loops challenged to different dilutions of enteropathogenic e. coli strains, no effect was observed to enterotoxin (lt) preparations. pectin seems to interact with the bacterial colonization. the neutralizing effect was most pronounced with low inoculation doses in the loops (10(3) and 10(5)), while high doses (10(9)) permitted the strains to exert their enteropathogenic effect (table i). different batches ga ... | 1981 | 7033924 |
| intramolecular coupling of active sites in the pyruvate dehydrogenase multienzyme complexes from bacterial and mammalian sources. | a simple method was developed for assessing the intramolecular coupling of active sites in the lipoate acetyltransferase (e2) component of the pyruvate dehydrogenase multienzyme complexes from escherichia coli, bacillus stearothermophilus and ox heart and pig heart mitochondria. samples of enzyme complex were prepared in which the pyruvate decarboxylase (e1) component was selectively and partly inhibited by treatment with increasing amounts of a transition-state analogue, thiamin thio-thiazolone ... | 1981 | 7032507 |
| escherichia coli resistant to tetracyclines and to other antibiotics in the faeces of u.k. chickens and pigs in 1980. | a survey conducted in 1980, 9 years after the banning of the use of tetracyclines as feed additives in the u.k., indicated that table chickens and pigs were still a large reservoir of tetracycline-resistant escherichia coli; the incidence of transferable tetracycline resistance was greater in chicken e. coli strains (68%) than in pig e. coli strains (20%). large amounts of sulphonamide-resistant and of furazolidone-resistant e. coli were found in the faeces of chickens; e. coli resistant to both ... | 1981 | 7031130 |
| chemotherapeutic activity of the combination of sulfachloropyridazine and trimethoprim against experimental colibacillosis of chickens and piglets and demonstration of the trimethoprim-induced potentiation of sulfachloropyridazine in vitro and in vivo. | 1981 | 7029707 | |
| [ca antibodies (enterobacteriaceae common antigen) in the sera of domestic animals]. | using the indirect hemagglutination test, antibodies against enterobacteriaceae common antigen (ca) were tested in the sera of 123 horses, 142 cows, 108 sheep, 142 mature pigs and 60 piglets (3-4 weeks of age). anti ca antibody level and antibody titers for somatic antigens (phenol-water extracts) various serogroups of e. coli (0149, 0138, 0115, 078, 09) and s. typhimurium were compared. ca antibodies in titer equal or higher than 1:15 were found to occur in 100% of the examined horses and cows, ... | 1981 | 7029490 |
| malate dehydrogenase: isolation from e. coli and comparison with the eukaryotic mitochondrial and cytoplasmic forms. | escherichia coli malate dehydrogenase has been isolated in homogeneous form by a procedure employing chromatography on deae-cellulose, 5-'amp-sepharose, and sephacryl-200. it is composed of two identical polypeptide chains each of mr = 32 500. like porcine mitochondrial malate dehydrogenase, it is devoid of tryptophan, but otherwise it is not particularly more similar in composition to one of the eukaryotic isozymes than to the other. however, amino-terminal sequence analysis of the first 36 res ... | 1981 | 7028159 |
| bacteriologic study of sow agalactia. | necropsy of 13 agalactic and 11 normally lactating sows at 1 to 2 days after parturition revealed that 7 of the agalactic and 4 of the clinically normal sows had lesions of mastitis. escherichia coli, streptococcus equisimilis, and staphylococcus epidermidis were the predominant organisms isolated. the organisms were isolated as pure and as mixed cultures and all 3 were isolated from normal appearing, as well as mastitic, glands. pure culture isolation of e. coli (44 gland segments) was signific ... | 1981 | 7025714 |
| organic acid proton donors decrease intestinal secretion caused by enterotoxins. | the effects of several weak acids on the secretory actions of cholera toxin and the heat-stable enterotoxin of escherichia coli (st) have been examined in ligated jejunal loops in weanling pigs. ascorbic and acetic acids had no effect, but l-lactic acid reduced the net fluid secretion caused by cholera toxin. glutaric acid and p-aminobenzoic acid blocked net fluid secretion caused by cholera toxin or by st. antisecretory effects were ph dependent for p-aminobenzoic acid in this study and for nic ... | 1981 | 7025660 |
| prevalences of various bioactive escherichia coli strains isolated from clinical materials in tokyo area in 1978. | 1980 | 7024609 | |
| 4'-methylangelicin derivatives: a new group of highly photosensitizing monofunctional furocoumarins. | the photobiological properties of three new angelicin derivatives carrying a methyl-group in 4' position at the furanic ring have been studied. in double-irradiation experiments on e. coli cells, they appeared to behave as monofunctional reactives towards dna, similarly to the other angelicin derivatives previously studied. in short-term experiments such as the studies on macromolecular synthesis in ehrlich ascites cells, in which the assay is performed that after irradiation, before dna repair ... | 1981 | 7023974 |
| a survey of antibiotic resistance of escherichia coli isolated from farm animals in great britain from 1971 to 1977. | a total of 94,827 escherichia coli strains isolated from cattle, sheep, pigs and poultry during the years 1971 to 1977 were tested for resistance to six antibiotics using a disc diffusion technique. the percentage of strains resistant to chloramphenicol (10 microgram), streptomycin (10 microgram), tetracycline (10 microgram), neomycin (10 microgram) and furazolidone (15) were 16.8, 53.9, 42.7, 18 and 10.9 per cent, respectively; 52.2 per cent of strains (1971 and 1972) were resistant to 2 microg ... | 1981 | 7020230 |
| polyserositis and meningitis associated with escherichia coli infection in piglets. | two piglets which had a history of anorexia and weakness were examined pre and postmortem. other piglets in the same herd had died within 24 hours of the onset of similar signs. the two piglets examined had a fibrinous polyserositis. grossly, the pleura, peritoneum and joints were affected and an acute meningitis was noted on microscopic examination of the brains. pure cultures of escherichia coli were recovered from all but one of the organs and exudates cultured. | 1981 | 7018661 |
| synergistic interaction of bactericidal drugs and a factor present in serum ultrafiltrate. | ultrafiltrate of serum of guinea-pig and man contains a factor which interacts synergistically with cephaloridine, kanamycin, and nalidixic acid against escherichia coli. the factor on its own is not bactericidal. gel filtration showed that the main peaks of the fractions with biological activity correspond to a mw of about 200. chemical analysis excluded the presence of carbohydrates, proteins, ribonucleic acid at levels detectable with standard methods. moreover the activity of the factor was ... | 1981 | 7018501 |
| escherichia coli vaccine for prevention of neonatal enteric colibacillosis in pigs. | 1980 | 7018203 | |
| [prophylaxis of colienterotoxemia in swine: duration of oral immunization with virulent pathogens combined with protective diet]. | 1981 | 7017925 | |
| [antibiotic resistance and transmission of r factors from e. coli and salmonella typhimurium, isolated from food samples of animal origin]. | 1981 | 7016497 | |
| the isolation of antibiotic resistant coliforms from meat and sewage. | beef and pig carcases, meat products, frozen chickens, and sewage were examined in 3 separate surveys for antibiotic resistant coliforms. escherichia coli was isolated from 18 of 50 beef carcases; the numbers were low and resistance was found only to tetracycline. e. coli was isolated from 45 to 50 pig carcases; the numbers were high and showed a range of patterns of multiple antibiotic resistance. in meat products, the proportion of e. coli in contaminating organisms was low, and most resistanc ... | 1981 | 7016108 |
| studies on the predisposing role of stress in the e. coli-diarrhoea of pigs. | 1980 | 7013371 | |
| k88-mediated binding of escherichia coli outer membrane fragments to porcine intestinal epithelial cell brush borders. | we have examined the interactions between various radiolabeled membrane fractions obtained from an enterotoxigenic escherichia coli strain and brush borders isolated from porcine intestinal epithelial cells. outer membrane fragments containing the k88 attachment factor bound tightly to brush borders, whereas cytoplasmic membrane vesicles did not. three different types of outer membrane preparations were tested: (i) cellular outer membranes isolated from lysozyme spheroplasts, (ii) medium vesicle ... | 1981 | 7012003 |
| internalization of 125i-insulin by im-9 cultured human lymphocytes: a comparison between a14-monoiodo-pork and biosynthetic human insulin. | human insulin synthesized from a- and b-chains separately produced in escherichia coli from cloned genes was characterized by examining its interaction biochemically and morphologically with im-9 cultured human lymphocytes. biosynthetic human insulin (bhi) behaves similarly to pork insulin with respect both to its binding properties and to the rate and magnitude at which it is internalized by the cells. | 1981 | 7011731 |
| comparison of the biologic activity of biosynthetic human insulin and natural pork insulin in juvenile-onset diabetic subjects assessed by the glucose controlled insulin infusion system. | to assess the biologic activity of biosynthetic human insulin (bhi) synthesized by escherichia coli, six insulin-dependent juvenile-onset diabetic subjects were studied with bhi and natural pork insulin, by means of the glucose controlled insulin infusion system (gciis). first, after an overnight normalization of blood glucose levels, the 24-h insulin requirement was determined while the patients were consuming a diet of 30 kcal/kg. then, the amount of glucose necessary to maintain normal blood ... | 1981 | 7011725 |
| sensitivities of escherichia coli isolated from bovine and porcine enteric infections to antimicrobial antibiotics. | the antibiotic sensitivities of escherichia coli isolated from 91 diarrheal pigs and 98 diarrheal calves were determined to 19 different microbials by the kirby-bauer method. virtually all e coli isolated from pigs and calves were sensitive to amikacin, colistin, gentamicin, and polymyxin b. in vitro minimum inhibitory concentrations for these 4 antibiotics were determined for isolates from both pigs and calves. | 1980 | 7011124 |
| the recovery of sublethally injured escherichia coli from frozen meat. | 1980 | 7007308 | |
| [biochemical investigations on the blood serum of piglets with colibacillosis (edema disease) (author's transl)]. | 1980 | 7006964 | |
| [experiences with the e. coli vaccines ecopig and porcovac]. | 1980 | 7004435 | |
| cephamycin c treatment of induced enterotoxigenic colibacillosis (scours) in calves and piglets. | cephamycin c is a beta-lactam antibiotic that has broad gram-negative activity and is resistant to degradation by beta-lactamases and safe for use in animals. in colostrum-fed calves infected with escherichia coli strain b44, cephamycin c administered by gavage at 31.3 to 1,000 mg per calf (0.75 to 24 mg/kg) twice a day for 6 days starting at 20 h post-inoculation eliminated the diarrhea and reduced the mortality from 90% in infected, nonmedicated calves to 14% in infected, medicated calves (p < ... | 1980 | 6999985 |
| [escherichia coli r live vaccine suicolplex "dessau"]. | immunisation of pregnant sows prior to parturition has long proved to be a good method to forestall coli dysentery in piglets before weaning. inactivated vaccines of the pathogenetically important e. coli serogroups with and without adjuvant so far were primarily used at international level. a vaccine of that kind has become available in the gdr more than eight years ago. its name is coliporc "dessau". a live vaccine has been developed from two r-mutants at the authors' institute. the effectiven ... | 1980 | 6998398 |
| [prospects for production of improved preparations of preventing infectious diseases]. | 1980 | 6998226 | |
| effects of iron on the anti-coli capacity of sow's milk in vitro and in ligated intestinal segments. | the effect of iron on the ability of sow's milk to suppress escherichia coli was examined both in vitro and in ligated intestinal segments of neonatal pigs. sow's milk from day 7 of lactation was diluted with nahco3/kh2po4 and divided into four treatment groups: (1) diluted milk; (2) diluted milk + ferric citrate; (3) diluted milk heated at 100 degrees for 20 minutes, and (4) treatment 3 + ferric citrate. treatment groups were tested for antibacterial activity in vitro after inoculation of 10(4) ... | 1980 | 6997445 |
| persistence and distribution of erysipelothrix rhusiopathiae and bacterial indicator organisms on land used for disposal of piggery effluent. | 1980 | 6997256 | |
| identification of a carbohydrate receptor recognized by uropathogenic escherichia coli. | earlier investigations have shown that pyelonephritic escherichia coli specifically recognize and bind to carbohydrate structures correlated to the p blood group antigens. these findings are confirmed and extended in this study. twenty-two of 23 nonselected e. coli strains from children with acute febrile pyelonephritis failed to agglutinate human erythrocytes lacking the antigens within the p blood group system. only one of 32 faecal isolates exhibited this specific agglutinating property. the ... | 1980 | 6997213 |
| the effects of laboratory animal diets on the potency tests of bacterial vaccines. | comparative studies of the responses elicited by mice fed on pcd and ffg diets to a number of bacterial vaccines have shown a significant reduction in the immune response to tetanus toxoid but not to clostridium septicum toxoid and increased resistance to challenge with e. coli and syngeneic tumour cells but not to pasteurella multocida. these differences cannot readily be explained in terms of differences between the identifiable constituents of the diets and illustrte the dangers of vaccine po ... | 1980 | 6995215 |
| influence of oral antibiotics on resistance and enterotoxigenicity of escherichia coli. | three groups of five piglets were formed and 1390 escherichia coli isolates were obtained during the 45-day period of observation. one of the groups received feed without antibiotic whereas the second received feed containing 100 ppm neomycin and the third feed with 100 ppm neomycin plus 100 ppm tetracycline. rectal swabbings for bacterial isolation were repeated ten times, twice during an adaptation period and eight times during the treatment period. resistance among the isolates to tetracyclin ... | 1980 | 6994861 |
| antibacterial antibodies in swine colostrum. | antibacterial antibody activities were examined in 138 samples of swine colostrum by o-agglutinin test with serotypes of escherichia coli (o-6, 0-45, 0-81, 0-83, 0-115, 0-138, o-139, and o-126), salmonella typhimurium, and salmonella cholerae suis. the mean agglutinin titer of e coli o-83 was the highest; e coli o-115 was next highest. the mean agglutinin titer of s cholerae suis was lowest; s typhimurium was next to lowest. correlation coefficients among these o-agglutinin titers were between 0 ... | 1980 | 6989301 |
| wound infection: a controlled clinical and experimental demonstration of synergy between aerobic (escherichia coli) and anaerobic (bacteroides fragilis) bacteria. | pathogenic synergy between escherichia coli and bacteroides fragilis was suggested by clinical trials and proved to exist in an experimental guinea-pig wound model. this finding is thought to have important theoretical and practical therapeutic implications. | 1980 | 6987938 |
| [usefulness of selected biological tests for detection of enteropathogenicity of escherichia coli strains isolated from children hospitalized for diarrhea]. | 1982 | 6820451 | |
| clindamycin: a review of fifteen years of experience. | clindamycin, the 7(s)-chloro-7-deoxy derivative of lincomycin, has stood the test of time in the treatment of anaerobic infections. clindamycin inhibits protein synthesis by acting on the 50s ribosomal subunits of bacteria. the colitis resulting from the use of clindamycin has been extensively studied and is now easily manageable. although newer antibiotics active against anaerobes are available, clindamycin remains a reliable and well-tested antibiotic for use in anaerobic infections. | 1982 | 6818656 |
| [the protective effect of an edta-sodium-extract-vaccine obtained from swine-pathogenic e. coli in a field trial. 2. communication: immunization of weanling piglets (author's transl)]. | pentavalent edta-sodium-extract vaccines and monovalent edta-sodium-extract vaccines obtained from swine-pathogenic e. coli were used to test their antiepizootic effect in industrial pig farms, 2929 piglets after weaning were included in this field trial, 1309 were immunized partly orally, partly i.m., 1620 piglets received placebos accordingly. by means of oral immunization the pentavalent vaccine was capable of reducing the morbidity of the vaccinated animals significantly. intramuscular immun ... | 1980 | 6775450 |
| bacterial adhesiveness and invasiveness in cell culture monolayer. 2. in vitro invasiveness of 45 strains belonging to the family enterobacteriaceae. | the invasive potential of 45 presumptive enteropathogenic and non-enteropathogenic bacterial strains belonging to the family enterobacteriaceae have been tested using the serény test and hep-2 cell monolayers examined by a combined light optical method. all the presumptive enteropathogenic strains of shigella dysenteriae, s. boydii, s. flexneri, s. sonnei and salmonella typhimurium showed in vitro invasiveness in the hep-2 cell culture test. fourteen presumptive non-enteropathogenic strains of e ... | 1982 | 6762798 |
| effects of epinephrine, clonidine, l-phenylephrine, and morphine on intestinal secretion mediated by escherichia coli heat-stable enterotoxin in pig jejunum. | perfusion of pig jejunum with escherichia coli heat-stable enterotoxin (strain 1261) reversed net absorption of water and electrolytes to net secretion. addition of the alpha-adrenergic agonists clonidine (5 x 10(-7) m) or l-phenylephrine (5 x 10(-6) m), or the opiate agonist morphine (3.6 x 10(-6) m) to the perfusate reduced the secretory response to enterotoxin and stimulated absorption in normal jejunum. epinephrine (5 x 10(-5) m) did not stimulate absorption in controls but reduced chloride ... | 1982 | 6762245 |
| [thymine-dependent mutants of swine-pathogenic edema e. coli of serotype 0139:82b]. | 1982 | 6762019 | |
| small filter membrane bags for the study of antibiotic action in the digestive tract: bioavailability and in situ efficacy of ampicillin in the pig caecum. | bioavailability and activity of ampicillin were evaluated in the pig after preventive and curative doses by using small filter membrane bags containing strains of escherichia coli placed into the caecum. a peak concentration of 720 micrograms ampicillin per ml was obtained in caecal liquor which was effective against e coli k82 and e coli 127 in the bags, in pigs orally administered with 20 mg/kg of the drug. after intramuscular injection of ampicillin with 40 mg/kg, the peak concentration in ca ... | 1982 | 6760305 |
| [harmless bacteria - harmful bacteria: unsolved problems of infectiology]. | 1982 | 6758178 | |
| [secretin production by genetic engineering]. | 1982 | 6754999 | |
| [alpha-neoendorphin]. | 1982 | 6754998 | |
| appearance of enterotoxigenic escherichia coli in piglets with diarrhea in connection with feed changes. | twelve weaned piglet (3-week-old) were divided into three groups according to time of feed change and observed for diarrhea during the time they were 3 to 8 weeks of age. a total of 553 strains of escherichia coli were isolated from rectal fecal samples and examined for heat-labile (lt) and heat-stable (st) enterotoxins, pilus antigens (k88, k99, and 987p), hemolysin (hly), raffinose utilization (raf) and drug resistance. enterotoxins and/or hemolytic e. coli strains appeared in the rectal feces ... | 1982 | 6752665 |
| different pig phenotypes affect adherence of escherichia coli to jejunal brush borders by k88ab, k88ac, or k88ad antigen. | at least five different porcine phenotypes were distinguished with the three serological variants of the k88 antigen in the brush border adhesion test. pigs of one phenotype (a) are susceptible to adherence of all three variants, pigs of three phenotypes are susceptible to only two (b and c) or one (d) of the k88 variants, and pigs of one phenotype (e) are entirely resistant to adhesion of k88 antigen did not interfere with the adhesion of k88ab- or k88ac-positive escherichia coli, whereas in mo ... | 1982 | 6752028 |
| evaluation of immunological methods for detection of bovine growth hormone (bgh) produced in e. coli. | the use of several immunological methods for studies on synthesis of bovine growth hormone (bgh) by e. coli is described here. the elisa procedure was shown to be the least sensitive and unfit for assaying bgh in e. coli extracts. the solid-phase radioimmunoassay (ria) proved to be highly sensitive, but since e. coli extract itself (not containing bgh) interfered with the immunological reaction, its use for measuring bgh was practically limited. the best adequate procedure proved to be radioimmu ... | 1982 | 6749998 |
| classification of trimethoprim-resistant dihydrofolate reductases mediated by r-plasmids using isoelectric focussing. | 1982 | 6749500 | |
| protein loss in piglets infected with different enteropathogenic types of escherichia coli. | 1982 | 6749257 | |
| safety evaluation of thaumatin (talin protein). | thaumatin, the sweet proteinaceous extract of the arils of thaumatococcus daniellii (benth.) has been studied for its subacute toxicity in rats and dogs and its ability to produce anaphylactic antibodies following oral administration to rats and normal human subjects. thaumatin was readily digested prior to absorption in rats and no adverse effects resulted from its continuous administration to rats and dogs at dietary concentrations of 0, 0.3, 1.0 and 3.0% for 13 wk. it was not teratogenic when ... | 1983 | 6686588 |
| [clinical, cytological and microbiological studies of the mma syndrome]. | clinical, cytological, and microbiological investigations were carried out of a total of 793 sows in the course of 10 days after farrowing. it was found that the mma syndrome was manifested in the first days following farrowing with higher temperature, changes in the genital organs with a purulent discharge from the first to the third day, and lesions in the mammary gland with inflammatory processes or decrease in the milk secretion. the cell content of milk of the diseased sows was higher. the ... | 1983 | 6659347 |
| [pharmacological, toxicological, microbiological and pathohistological studies of gentamycin complex ii]. | the acute toxicity was determined of the gentamycin complex ii (gmc-ii) for albino mice, containing gentamycin components in a varying ratio. the ld50 at intraperitoneal application was 347.7 mg/kg body mass, while at oral application it was 5,180 mg (4933 divided by 5439) mg/kg body mass. histopathologically, (mice killed with high doses of gmc-ii, given orally) there were diffuse hyperemia of the liver, parenchymal degeneration of the kidney tubuli epithelium, and edema and emphysema of the lu ... | 1983 | 6623911 |
| pathomorphology and pathogenesis of bacterial meningoventriculitis of neonatal ungulates. | bacterial meningoventriculitis was studied in 26 neonatal ungulates. preceded by a substantial bacteremia, usually due to escherichia coli, the fibrinopurulent inflammation involved leptomeninges, choroid plexuses, and ventricle walls, but largely spared the neuraxial parenchyma. it is proposed that this surface-relatedness results from the transport of bacteria by monocytes of low bactericidal power, migrating by normal pathways to maintain significant surface populations of macrophages. the ne ... | 1984 | 6516179 |
| a note on the use of the spiral plater to study the in vitro effects of amoxycillin, spectinomycin and chloramphenicol on a porcine escherichia coli. | 1981 | 6457824 | |
| direct and indirect effects of endotoxin on mitochondrial function. | 1981 | 6456464 | |
| therapeutic efficacy of a new cephamycin, mt-141, in compromised mice. | the antibacterial activity of mt-141 against escherichia coli and proteus morganii in compromised mice was investigated and compared with that of latamoxef, cefmetazole and cefoxitin. the bactericidal activity of mt-141 in short-term contact with e. coli and p. morganii was markedly enhanced when combined with mouse serum, and the activity of mt-141 was greater than the activities of the three reference drugs. the antibacterial activities of mt-141 in the liver, spleen and kidney of neutropenic ... | 1984 | 6441793 |
| [phospholipase activity of the membrane fraction of phagocytes in relation to its antibacterial property]. | 1984 | 6436567 | |
| f41 antigen among porcine enterotoxigenic escherichia coli strains lacking k88, k99, and 987p pili. | colonial morphological variations among enterotoxigenic escherichia coli which lack k88, k99, and 987p (3p-) were shown to be correlated with expression of several surface antigens, i.e., type 1 pili, f41 pili, and somatic and capsular antigens. such correlations were established by electron microscopy, serology, and hemagglutination of cells derived from these specific colonial types. identification of f41 produced by the 3p- enterotoxigenic e. coli strains was made by immunodiffusion in agaros ... | 1984 | 6420345 |
| [a possible way of improving colibacterin]. | 1984 | 6401093 | |
| escherichia coli originated from diarrhea of suckling piglets in taiwan. ii. serological properties. | 1984 | 6399334 | |
| portal and systemic plasma vip and secretin during intravenous infusion of escherichia coli endotoxin in pigs. | plasma vasoactive intestinal polypeptide (vip) increased significantly in the portal vein, the superior caval vein, the internal jugular vein, and the aorta during an intravenous infusion of e. coli endotoxin in six anesthetized pigs, which all developed a deep shock, with fall in aortic blood pressure and urinary output. plasma vip peaked simultaneously with the most pronounced shock symptoms, and the level in the portal vein was significantly higher than in blood from the other sampling sites. ... | 1984 | 6398505 |
| significance of thermostable enterotoxin produced by porcine enteropathogenic escherichia coli. | 1984 | 6393557 | |
| persistent hyperinsulinemia due to induced euglycemia in awake endotoxic minipigs. | transient hyperinsulinemia has been incriminated as a contributing factor to endotoxin-induced hypoglycemia. however, a recent study using endotoxic minipigs noted an increase in the rate of glucose utilization prior to when hyperinsulinemia was seen. based on this, the "misinformed beta-cell" hypothesis was proposed. if endotoxic pancreatic beta-cells experience an early increase in glucose uptake, they could over-estimate the true glycemic state and release insulin, further contributing to the ... | 1984 | 6391719 |
| does enteropathogenic escherichia coli produce heat-labile enterotoxin, heat-stable enterotoxins a or b, or cholera toxin a subunits? | although most enteropathogenic escherichia coli strains do not produce recognized enterotoxins, we wished to examine whether they produce any factors like heat-stable enterotoxin b or cholera toxin active subunits that might be missed by conventional assay methods. e. coli strains e851 (o142) and e2348 (o127) that had caused diarrhea in volunteers were negative for heat-labile enterotoxin and heat-stable enterotoxin a in chinese hamster ovary cell and suckling mouse assays, failed to cause secre ... | 1984 | 6389354 |
| [changes in the white blood picture and the t- and b-lymphocyte counts in the peripheral blood of pigs after treatment with e. coli endotoxin]. | studied were the changes in the total count of the white blood cells, the leukocyte formula, and the t- and b-lymphocytes of young pigs (2-3 months old) at various intervals following treatment with an e. coli enterotoxin. it was found that there set in an essential drop of the total count of the white blood cells during the first 24 hours after treatment, with a following rising trend. there were also characteristic changes in the ratio between the various types of white blood cells, with a ris ... | 1984 | 6388144 |
| quaternary heterocyclylamino beta-lactams. v. l-640,876 treatment of induced enterotoxigenic colibacillosis (scours) in calves and piglets. | a new semisynthetic cephalosporin antibiotic designated l-640,876, 7-beta-(1-benzylpyridinium-4-yl)amino-3-[( (1-methyl-1h-tetrazol-5-yl)thio] methyl)ceph-3-em-4-carboxylate, was highly active in vitro against 110 enteropathogenic strains of escherichia coli and salmonella species of animal origin. the mic90 was 0.125 microgram/ml for the e. coli strains, 2 micrograms/ml for the s. choleraesuis strains and 4 micrograms/ml for the s. typhimurium strains. in colostrum-fed calves infected with e. c ... | 1983 | 6381448 |
| naloxone therapy in awake endotoxemic yucatan minipigs. | twelve yucatan miniature pigs were fitted with jugular, portal, hepatic vein, and carotid artery catheters, and hepatic artery and portal vein flow cuffs to quantitate portosystemic and transhepatic kinetics. seventy-two hours later they were placed in slings, and following a 3-hr control period were infused with escherichia coli endotoxin at 15 micrograms/kg/hr for 6 hr. eight were controls and 4 received a primed (2 mg/kg) continuous infusion (2 mg/kg/hr) of naloxone 1 hr after initiation of e ... | 1984 | 6379299 |
| attachment of human and pig (k88) enterotoxigenic escherichia coli strains to either human or porcine small intestinal cells. | enterotoxigenic escherichia coli strains pathogenic for humans and enterotoxigenic e. coli strains pathogenic for pigs producing the k88 pili antigen both bound to isolated small intestinal cells from either humans or pigs. neither the k99 enterotoxigenic e. coli (from lambs and calves) nor the rabbit pathogenic strain rdec-1 bound to human or pig small intestinal cells under the same conditions. | 1984 | 6378801 |
| divergent patterns of leucocyte locomotion in experimental post-traumatic osteomyelitis. | leucocyte locomotion (ll) was evaluated in guinea-pigs with experimental post-traumatic osteomyelitis. surgical procedure (fracture of the right femur), the number of micro-organisms applied to the fractured site and the time sequence of investigations were kept constant. after the right femur of guinea-pigs had been fractured, the animals were divided into three groups: in group i the fractured site remained uninfected, while in groups 2 and 3 the fractured sites were infected with either esche ... | 1984 | 6378240 |
| antimicrobial resistance and conjugative r plasmids in escherichia coli strains isolated from animals in peninsular malaysia. | fifteen independent e. coli strains of avian, bovine and porcine origin in peninsular malaysia were tested for antibiotic resistance and conjugative r plasmids. eight (53%) isolates were found to be antibiotic resistant. among them, 37.5% were mono-resistant and 62.5% were resistant to three or more antibiotics, i.e., multi-resistant. all of them were resistant to tc and sensitive to gm and nx. three of the eight antibiotic resistant strains were able to transfer all or part of their resistance ... | 1984 | 6377513 |
| [amino acid composition of the alpha-ketoglutarate dehydrogenase from the breast muscle of the pigeon]. | the amino acid composition of alpha-ketoglutarate dehydrogenase--a component of alpha-ketoglutarate dehydrogenase complex--from the pigeon breast muscle has been determined. a significant similarity of the enzyme amino acid composition isolated from systematically remote species has been revealed by comparison of the data obtained with the literary one concerning the alpha-ketoglutarate dehydrogenase from escherichia coli and pig heart. | 1984 | 6375738 |
| [trends in drug therapy: electolyte transport in the intestines. the pathophysiology and therapy of enterotoxin-caused diarrheas]. | 1984 | 6375654 | |
| the role of dietary antigen in the aetiology of post weaning diarrhoea. | experiments were undertaken to investigate whether a hypersensitivity response to dietary antigen might be a predisposing factor in the aetiology of post weaning diarrhoea. the results indicated that: 1. very small amounts of food given to baby pigs before weaning significantly increased the severity and accelerated the onset of the disease; 2. post weaning diarrhoea was dependent upon the presence within the diet of antigenic material; 3. weaning diets containing little antigenic material had l ... | 1983 | 6375529 |
| dietary regimen, rotavirus, and hemolytic enteropathogenic escherichia coli in weanling diarrhea of pigs. | previously, we induced weanling diarrhea in piglets by infecting them first with rotavirus followed by a hemolytic enteropathogenic escherichia coli. we postulated that rotavirus, by damaging the epithelium of the small intestines, produced an entero-environment which favored the selection and growth of the enteropathogenic e. coli. furthermore, diet might affect the entero-environment and influence the course of the disease. to test this, newly weaned 3-week-old piglets were assigned to one of ... | 1983 | 6375527 |
| [properties of e. coli isolated from pigs]. | a total of 127 strains of escherichia coli were isolated from the small intestine, mesenterial lymph nodes, and parenchymal organs from dead pigs or pigs that were killed for diagnostic purpose as well as from rectal swab samples taken from diseased or clinically normal animals. all were studied with regard to haemolytic properties via biochemical and serologic methods along for sensitivity to antibiotics. it was found that the isolated strains manifested characteristic biochemical behaviour (79 ... | 1984 | 6375116 |
| [immunogenesis of 2 live vaccines against swine colibacillosis]. | comparative testing was carried out on a farm with 2 live vaccines against coli bacteriosis . studied were blood and milk sera taken from test and control pigs and blood sera from pigs born by them. both the test and control groups were clinically followed up with recording the morbidity and mortality indices. it was found that the titer of the k88 antibodies rose after vaccination with the two vaccines and retained its level up to the 30th day after farrowing. the titer of the o antibodies rema ... | 1984 | 6375113 |
| the reaction of pyridoxal phosphate with holoenzymes in the pyridoxamine phosphate form. | 1984 | 6374674 | |
| prevention of colibacillosis in neonatal swine with a 4-pilus e coli bacterin. | of 12 pregnant swine (vaccinates) given a 4-pilus enterotoxigenic e coli (etec) bacterin (k88, k99, 987p, f41), all developed comparable or significantly higher serum and colostral antibody levels than those of 8 pregnant swine (controls) given a 3-pilus etec bacterin (k88, k99, 987p). when piglets were challenged with an etec strain bearing the f41 antigen, those from vaccinates had significantly lower mortality, less scours, less severe clinical signs and better weight gain than those from con ... | 1984 | 6374422 |
| drug resistance and conjugative r plasmids in fecal escherichia coli strains isolated from healthy younger animals (chickens, piglets, calves) and children. | a total of 11,777 escherichia coli strains were isolated from 90 chickens, 103 piglets, 96 calves, and 104 children in 1979 in gunma prefecture and tested for drug resistance and the presence of conjugative r plasmids. the percentages of individuals that excreted drug-resistant strains were: chickens, 100%; piglets, 99%; calves, 100%; and children, 64%. the frequency of isolation of drug-resistant strains among the total isolates was: chickens, 98%; piglets, 93%; calves, 94%; and children, 41%. ... | 1983 | 6374389 |
| enteric diseases in animals caused by escherichia coli: their control and prevention. | 1984 | 6373433 | |
| study of several factors affecting the agglutinating activity of k99-positive escherichia coli strains. | the effect of several factors on escherichia coli k99-plasmid associated agglutination has been studied. the results obtained indicate that escherichia coli 637 (k99+) mediated red blood cell agglutination is unspecific although the agglutination titres for several erythrocyte species are significantly different. the agglutination is highly stable (at least with sheep red blood cells) to changes in temperature (from 4 degrees c to 37 degrees c), to changes in ph (from 5 to 9) and to the presence ... | 1983 | 6371953 |
| relationship of iron administration to susceptibility of newborn pigs to enterotoxic colibacillosis. | to determine whether supplemental iron (fe) administration to newborn pigs reared in concrete pens not only prevents anemia, but renders the pigs more susceptible to escherichia coli-induced diarrheal disease, pigs were given a large or a small dose of fe im or orally before or after challenge exposure with e coli. the controls were challenge-exposed pigs not given fe and pigs not challenge exposed (fe-treated and nontreated groups). although the mortality of the pigs challenge exposed with e co ... | 1984 | 6370051 |
| [dynamics of antibiotic resistance of strains of escherichia coli isolated from feces of weaned piglets (the case of the lwanika- lubumbashi (zaire) farm]. | 1983 | 6369447 | |
| effect of bacterial immunization on experimental reflux nephropathy. | this study was designed to test the hypothesis that young animals with vesicoureteral reflux might be more vulnerable to renal parenchymal infection by bacteria to which they had not been previously exposed. forty-four crossbred male piglets had surgical induction of vesicoureteral reflux at 2 weeks of age and introduction of urinary tract infection at 6 weeks. they were sacrificed at 12 weeks of age. between the ages of 2 and 6 weeks, 22 piglets received subcutaneous injections of formalin-kill ... | 1984 | 6368870 |
| heme-iron and ecology of escherichia coli within the porcine gut. | growth of escherichia coli was followed in sow whey by a turbidometric technique. heme-iron clearly promoted bacterial growth, therefore free heme would be dangerous in small intestine by enhancing bacterial growth: duodenal brush border membrane (bbm) was seen to bind heme-iron, thus abolishing the growth promoting effect of this form of iron. scatchard analysis of heme-binding onto bbm showed that heme became bound by a specific mechanism (kd approximately equal to 10(-7) m) as well as non-spe ... | 1983 | 6368116 |
| role of peripheral pooling in porcine escherichia coli sepsis. | in anesthesized pigs the effects of e. coli (2 x 10(8)/kg) on hemodynamics and red cell distribution were studied. after injection of 99m-tc red cells (15 mci), regional radioactivity was followed during 3 hours. gated bloodpool studies were performed to measure end-diastolic volumes (edv). escherichia coli e. coli was infused in 14 pigs, while 7 animals served as controls. e. coli resulted in an early increase in pulmonary arterial pressure. systemic arterial pressure decreased gradually, while ... | 1984 | 6368039 |
| antisecretory effects of berberine with morphine, clonidine, l-phenylephrine, yohimbine or neostigmine in pig jejunum. | the effects of berberine alone or in combination with morphine, clonidine, l-phenylephrine or yohimbine were compared in escherichia coli heat-stable enterotoxin (st)-exposed ligated jejunal loops in 2 week old pigs. in addition, net water and electrolyte fluxes in normal jejunal loops were measured in the presence of neostigmine, morphine, clonidine, l-phenylephrine or yohimbine alone or in combination with berberine. berberine, morphine, clonidine and l-phenylephrine each reduced the net secre ... | 1983 | 6363101 |
| [passive immunoprophylaxis against coli dysentery of suckling pigs by vaccination of sows with attenuated escherichia coli mutants. 1. clinical and laboratory diagnostic results of the combined use of k88- and k99-antigen-containing strains derived from escherichia coli mutants]. | 1983 | 6362603 | |
| the clinical manifestation and pathogenesis of enteritis associated with rotavirus and enterotoxigenic escherichia coli infections in domestic animals. | rotavirus and enterotoxigenic escherichia coli (etec) are enteropathogens each capable of inducing diarrhoea in some animal species and man. unstressed young animals develop an age-related resistance to infection with either rotavirus or etec which differs for each animal species. the effects of experimental infection of calves, lambs, foals and piglets with rotavirus and etec given either alone or in combination, have been examined. in general, dual infections tended to lengthen the period of a ... | 1983 | 6361857 |